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Cyclosporin U is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Ciclosporin Impurity D; 1,11-Anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-L-leucine]; [Leu11]Ciclosporin A; Ciclosporin U; Ciclosporin EP Impurity D; 11-L-Leucine-Cyclosporin A; Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-L-leucyl); 11-L-Leucinecyclosporin A; Cyclosporine EP Impurity D; Cyclo[[(E)-(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl]-L-2-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl]. Grade: 95%. CAS No. 108027-45-8. Molecular formula: C61H109N11O12. Mole weight: 1188.61.
Cyclosporin U
Cyclosporin U. Uses: For analytical and research use. Group: Impurity standards. CAS No. 108027-45-8. Molecular formula: C61H109N11O12. Mole weight: 1188.61. Catalog: APB108027458.
10-[(2S)-2-Aminobutanoic acid]cyclosporin A
Cyclosporin Impurity 5 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Ciclosporin Impurity F; 1,11-Anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-(2S)-2-aminobutanoyl-N-methyl-L-leucine]; [Abu10]ciclosporin A; Cyclosporin Impurity 5; Cyclosporin A, 10-[(2S)-2-aminobutanoic acid]-; [Abu5]cyclosporin; cyclo[Abu-Sar-N(Me)Leu-Abu-N(Me)Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)]; cyclo[(N-(((2S)-2-aminobutyryl)-sarcosyl-N-methyl-L-leucyl)-(2S)-2-aminobutyryl)-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-(4R)-4-[(E)-but-2-enyl]-4-methyl-L-threonyl]; (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-21,30-Diethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3-isopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone; Ciclosporin EP Impurity F; [Abu10]cyclosporine A; Cyclosporine Abu-5 Impurity. Grade: ≥95%. CAS No. 437611-17-1. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine]cyclosporin a
6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine]cyclosporin a. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine] Cyclosporin A, 121584-52-9. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 121584-52-9. Molecular formula: C62H109N11O14. Mole weight: 1232.59. Purity: 0.96. IUPACName: [(3R,14S)-5-(dimethylamino)-3,15-dimethyl-14-[[(2S)-4-methyl-2-(methylamino)pentanoyl]amino]-1,6,13-trioxohexadecan-4-yl] acetate. Canonical SMILES: CC(C)CC(C(=O)NC(C(C)C)C(=O)CCCCCCC(=O)C(C(C(C)CC=O)OC(=O)C)N(C)C)NC. Product ID: ACM121584529. Alfa Chemistry ISO 9001:2015 Certified.
6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine] Cyclosporin A
6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine] Cyclosporin A is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (2S,5R,8S,11S,14S,17S,20S,26S,29S,32S)-8,11,26,32-Tetraisobutyl-20-ethyl-14,29-diisopropyl-2,5,7,10,13,16,22,25,31-nonamethyl-17-[(1R,2R)-1-acetoxy-2-methyl-4-oxobutyl]-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-3,6,9,12,15,18,21,24,27,30,33-undecaone; Cyclosporine EP Impurity A; Cyclosporin A, 6-[(3R,4R)-3-(acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine]-; Acetyl Cyclosporin A aldehyde. Grade: 98%. CAS No. 121584-52-9. Molecular formula: C62H109N11O14. Mole weight: 1232.59.
6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine] Cyclosporin A
Intermediate for the preparation of Cyclosporin derivatives for the treatment of immune disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 121584-52-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Cyclosporin A, 9-(4-hydroxy-N-methyl-L-leucine)-
Cyclosporin A, 9-(4-hydroxy-N-methyl-L-leucine)- is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporin Impurity 19. CAS No. 107335-26-2. Molecular formula: C62H111N11O13. Mole weight: 1218.63.
Cyclosporin a sulfate
Cyclosporin a sulfate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cyclosporin A Hydrogen Sulfate (ester). Product Category: Heterocyclic Organic Compound. CAS No. 121673-00-5. Molecular formula: C62H111N11O15S. Mole weight: 1282.67. Purity: 0.96. Product ID: ACM121673005. Alfa Chemistry ISO 9001:2015 Certified.
Cyclosporin A sulfate
Cyclosporin A sulfate. Group: Biochemicals. Alternative Names: Cyclosporin A hydrogen sulfate (ester). Grades: Highly Purified. CAS No. 121673-00-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C62H111N11O15S. US Biological Life Sciences.
Worldwide
Cyclosporin A Sulfate
Cyclosporin A Sulfate is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Uses: A metabolite of cyclosporin a. Synonyms: Cyclosporin A Hydrogen Sulfate (ester); Cyclosporine Sulfate; (1R,2R,4E)-1-[(2S,5S,11S,14S,17S,20S,23R,26S,29S,32S)-5-Ethyl-11,17,26,29-tetraisobutyl-14,32-diisopropyl-1,7,10,16,20,23,25,28,31-nonamethyl-3,6,9,12,15,18,21,24,27,30,33-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2-yl]-2-methyl-4-hexen-1-yl hydrogen sulfate. Grade: 95%. CAS No. 121673-00-5. Molecular formula: C62H111N11O15S. Mole weight: 1282.67.
Cyclosporine Impurity 1
Cyclosporine Impurity 1 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (4S,5R)-5-((R,E)-hex-4-en-2-yl)-3-methyl-2-oxo-N-((4S,7S,10R,13S,16S,19S,22S,28S)-4,7,16,22-tetraisobutyl-19-isopropyl-8,10,13,17,23,26-hexamethyl-3,6,9,12,15,18,21,24,27-nonaoxo-2,5,8,11,14,17,20,23,26-nonaazatriacontan-28-yl)oxazolidine-4-carboxamide. Grade: ≥95%. Molecular formula: C57H101N11O12. Mole weight: 1132.50.
Cyclosporine Impurity 3 Sodium Salt
Cyclosporine Impurity 3 Sodium Salt is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Grade: ≥90% by HPLC. Molecular formula: C7H14NO3Na. Mole weight: 183.18.
Cyclosporine Resolution Mixture
This material is an approximate 100:1 (w/w) mixture of cyclosporine and cyclosporine U (USP).
Cyclosporine Resolution Mixture
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Cyclosporin Impurity 10
Cyclosporin Impurity 10 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Molecular formula: C62H109N11O11. Mole weight: 1184.62.
Cyclosporin Impurity 11
Cyclosporin Impurity 11 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-33-((R,E)-2-methylhex-4-en-1-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone. Molecular formula: C63H113N11O11. Mole weight: 1200.66.
Cyclosporin Impurity 12
Cyclosporin Impurity 12 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Grade: ≥95%. CAS No. 1907654-63-0. Molecular formula: C58H103N11O12. Mole weight: 1146.53.
Cyclosporin Impurity 13
Cyclosporin Impurity 13 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Molecular formula: C25H29NO5. Mole weight: 423.51.
Cyclosporin Impurity 14
Cyclosporin Impurity 14 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 4-Oxazolidinecarboxylic acid, 3-methyl-5-(1-methyl-3-pentenyl)-2-oxo-, [4S-[4α,5β(1S*,3E)]]-; (4S,5R)-3-Methyl-5-((E)-(R)-1-methyl-pent-3-enyl)-2-oxo-oxazolidine-4-carboxylic acid; (4S,5R)-3-N-methyl-5-[((1R,3E)-1-methyl-3-penten)-1-yl]oxazolidin-2-one-4-carboxylic acid. CAS No. 81135-41-3. Molecular formula: C11H17NO4. Mole weight: 227.26.
Cyclosporin Impurity 2
Cyclosporin Impurity 2 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (2S,3R,4R,E)-3,8-dihydroxy-4-methyl-2-(methylamino)oct-6-enoic acid. Grade: ≥90% by HPLC. Molecular formula: C10H19NO4. Mole weight: 217.26.
Cyclosporin Impurity 3 Sodium Salt
Cyclosporin Impurity 3 Sodium Salt is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 4-hydroxy-4-methyl-2-(methylamino)pentanoic acid, sodium salt (1:1). Grade: ≥95%. Molecular formula: C7H14NNaO3. Mole weight: 183.18.
Cyclosporin Impurity 4
Cyclosporin Impurity 4 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 4-(2E)-2-Buten-1-yl-2,4,5-trideoxy-2-(methylamino)-L-xylonic acid; (2S,3R,4R,E)-3-Hydroxy-4-methyl-2-(methylamino)oct-6-enoic acid; 6-Octenoic acid, 3-hydroxy-4-methyl-2-(methylamino)-, (2S,3R,4R,6E). Grade: ≥90% by HPLC. CAS No. 59865-23-5. Molecular formula: C10H19NO3. Mole weight: 201.26.
Cyclosporin Impurity 6
Cyclosporin Impurity 6 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Grade: ≥90% by HPLC. CAS No. 1357559-31-3. Molecular formula: C8H15BF3N2K. Mole weight: 246.13.
Cyclosporin Impurity 7
Cyclosporin Impurity 7 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporin A, 6-[(2S,3R,4R,6E)-3-(acetyloxy)-8-bromo-4-methyl-2-(methylamino)-6-octenoic acid]-; (3R,4R)-N-Methyl-3-acetoxy-5-[(E)-3-bromo-1-propenyl]-cyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-); (1R,2R,E)-6-Bromo-1-((2S,5S,11S,14S,17S,20S,23R,26S,29S,32S)-5-ethyl-11,17,26,29-tetraisobutyl-14,32-diisopropyl-1,7,10,16,20,23,25,28,31-nonamethyl-3,6,9,12,15,18,21,24,27,30,33-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2-yl)-2-methylhex-4-en-1-yl acetate. Grade: ≥95%. CAS No. 138957-22-9. Molecular formula: C64H112BrN11O13. Mole weight: 1323.57.
Cyclosporin Impurity 8
Cyclosporin Impurity 8 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (E)-Trimethyl(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-en-1-yl)silane; 1-(Trimethylsilyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-1-propene; 1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-[(2E)-3-(trimethylsilyl)-2-propen-1-yl]-; Trimethyl[(1E)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-propen-1-yl]silane. Grade: ≥95%. CAS No. 79309-68-5. Molecular formula: C12H25BO2Si. Mole weight: 240.23.
Cyclosporin Impurity 9
Cyclosporin Impurity 9 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Molecular formula: C62H111N11O12. Mole weight: 1202.64.
Cyclosporin L Related Compound 1
Cyclosporin L Related Compound 1 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (E)-(R)-2-Methyl-hex-4-enoic acid. Grade: ≥90% by HPLC. CAS No. 93553-73-2. Molecular formula: C7H12O2. Mole weight: 128.17.
Cyclosporin L Related Compound 2
Cyclosporin L Related Compound 2 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (R,E)-2-methylhex-4-en-1-ol; (E)-(R)-2-Methyl-hex-4-en-1-ol; (2R,4E)-2-Methyl-4-hexen-1-ol; 4-Hexen-1-ol, 2-methyl-, (2R,4E)-. Grade: ≥90% by HPLC. CAS No. 104372-56-7. Molecular formula: C7H14O. Mole weight: 114.18.
Cyclosporin L Related Compound 3
Cyclosporin L Related Compound 3 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (E)-(2R,3S,4R)-2-Amino-3-hydroxy-4-methyl-oct-6-enoic acid; (2R,3S,4R,6E)-2-amino-3-hydroxy-4-methyl-6-octenoic acid; 2-Amino-4-[(2E)-2-buten-1-yl]-2,4,5-trideoxy-L-arabinonic acid; L-Arabinonic acid, 2-amino-4-[(2E)-2-buten-1-yl]-2,4,5-trideoxy-. Grade: ≥90% by HPLC. CAS No. 174292-85-4. Molecular formula: C9H17NO3. Mole weight: 187.24.
Des(N-Methyl-leucyl), Leucyl Cyclosporin A seco(MeGly-MeLeu) Carboxylic Acid
Des(N-Methyl-leucyl), Leucyl Cyclosporin A seco(MeGly-MeLeu) Carboxylic Acid is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine. Molecular formula: C63H113N11O14. Mole weight: 1248.64.
Des(N-Methyl-leucyl), N-tert Butyloxycarbonyl-leucyl Cyclosporin A seco(MeGly-MeLeu) Carboxylic Acid
Des(N-Methyl-leucyl), N-tertButyloxycarbonyl-leucyl Cyclosporin A seco(MeGly-MeLeu) Carboxylic Acid is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine. Molecular formula: C68H121N11O16. Mole weight: 1348.75.
Des(N-Methyl-leucyl), N-tert Butyloxycarbonyl-leucyl Cyclosporin A seco(MeGly-MeLeu) Methyl Ester
Des(N-Methyl-leucyl), N-tertButyloxycarbonyl-leucyl Cyclosporin A seco(MeGly-MeLeu) Methyl Ester is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester. Molecular formula: C69H123N11O16. Mole weight: 1362.78.
Iso Cyclosporin H Trifluoroacetic Acid Salt
Iso Cyclosporin H is an impurity of Cyclosporin H (C988920). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C62H111N11O12; x(C2HF3O2). US Biological Life Sciences.
Worldwide
Iso Cyclosporin H Trifluoroacetic Acid Salt
Iso Cyclosporin H Trifluoroacetic Acid Salt is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-D-valine (11→1)-Lactone Trifluoroacetic Acid Salt; 10-(N-Methyl-D-valine)isocyclosporin A Trifluoroacetic Acid Salt; Cyclosporine Impurity 19 Trifluoroacetic Acid Salt; D-Valine, (2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-, (11→1)-lactone, Trifluoroacetic Acid Salt; Isocyclosporin H Trifluoroacetic Acid Salt. Grade: ≥90% by HPLC. Molecular formula: C62H111N11O12.C2HF3O2. Mole weight: 1316.63.
(1,11-seco)-Cyclosporin A Oxazolidinone Methylamide
(1,11-seco)-Cyclosporin A Oxazolidinone Methylamide, is an impurity of Cyclosporin A (C988900), which is an immunosuppressant drug widely used in organ transplantation to prevent rejection. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C65H114N12O14, Molecular Weight: 1234.60799999999. US Biological Life Sciences.
1,3-Dimethyl-5-(2-methyl-4-hexenylidene)-2-thioxo-4-imidazolidinone is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 4-Imidazolidinone, 1,3-dimethyl-5-(2-methyl-4-hexen-1-ylidene)-2-thioxo-; 1,3-Dimethyl-5-(2-methyl-4-hexen-1-ylidene)-2-thioxo-4-imidazolidinone; 4-Imidazolidinone, 1,3-dimethyl-5-(2-methyl-4-hexenylidene)-2-thioxo-. CAS No. 59865-22-4. Molecular formula: C12H18N2OS. Mole weight: 238.35.
[2R-[2α(S*),3β,5β]]-5-Ethyltetrahydro-3-methyl-α-(methylamino)-2-furanacetic Acid is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 2-Furanacetic acid, 5-ethyltetrahydro-3-methyl-α-(methylamino)-, [2R-[2α(S*),3β,5β]]-. CAS No. 127605-69-0. Molecular formula: C10H19NO3. Mole weight: 201.26.
An impurity of cyclosporin. Cyclosporin is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Molecular formula: C62H111N11O12. Mole weight: 1202.64.
4-[2-(Dimethylamino)ethoxy]benzaldehyde
4-[2-(Dimethylamino)ethoxy]benzaldehyde is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: p-[2-(Dimethylamino)ethoxy]benzaldehyde; 4-(N,N-dimethylaminoethoxy)benzaldehyde; 4-(2-dimethylamino-1-ethoxy)benzaldehyde; Benzaldehyde, 4-[2-(dimethylamino)ethoxy]-. Grade: ≥95%. CAS No. 15182-92-0. Molecular formula: C11H15NO2. Mole weight: 193.24.
9-(N-Methyl-L-valine)cyclosporin A
9-(N-methyl-L-valine)cyclosporin A is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane, cyclic peptide deriv.; N-Methyl-valyl-4-cyclosporin A; N-Methyl-Val-4-CsA; SDZ 220-384; cyclo[Abu-Sar-N(Me)Val-Val-N(Me)Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)]; cyclo[((2S)-2-aminobutyryl)-sarcosyl-N-methyl-L-valyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-(4R)-4-[(E)-but-2-enyl]-4-methyl-L-threonyl]; Cyclosporin A, 9-(N-methyl-L-valine)-. CAS No. 156047-28-8. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Acetoxy Cyclosporin A Acetate
Intermediate in the preparation of Cyclosporin A. Group: Biochemicals. Alternative Names: 6-[(3R,4R,6E)-3,8-Bis(acetyloxy)-6,7-didehydro-N,4-dimethyl-L-2-aminooctanoic acid]cyclosporin A. Grades: Highly Purified. CAS No. 138957-23-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Alisporivir
Alisporivir, also known as DEB-025, a non-immunosuppressive cyclosporine A derivative, is acyclophil ininhibitor molecule with potent anti-hepatitis C virus (HCV) activity. Treatment with alisporivir alone or combined with PEGylated IFNalpha2a reduced the viral load in patients with chronic HCV infection. Synonyms: cyclo[Abu-N(Me)D-Ala-Xaa-Val-N(Me)Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)]; (3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-diethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,27,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21,24-tri(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone; alisporivir; DEBIO-025; MeAla(3)EtVal(4)-cyclosporin; UNIL 025; UNIL-025; UNIL025. Grade: 98.15%. CAS No. 254435-95-5. Molecular formula: C63H113N11O12. Mole weight: 1216.64.
Cilastatin Ammonium Salt
Cilastatin Ammonium Salt is the ammonium salt of Cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Synonyms: (2Z)-7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid Ammonium Salt; MK-791 Ammonium Salt. Grade: > 95%. CAS No. 877674-82-3. Molecular formula: C16H29N3O5S. Mole weight: 375.48.
Cilastatin sodium
Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Synonyms: L 642957; MK 791; L642957; MK791; L-642957; MK-791; [R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt; (2Z)?-7-[[(2R)?-2-Amino-2-carboxyethyl]?thio]?-2-[[[(1S)?-2,?2-dimethylcyclopropyl]?carbonyl]?amino]?-2-heptenoic Acid Sodium Salt; sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate. Grade: 98%. CAS No. 81129-83-1. Molecular formula: C16H25N2NaO5S. Mole weight: 380.43.
Cyclosporin
Cyclosporin is a cyclic decapeptide that could be isolated form the soil fungi Tolypocladium inflatum. Cyclosporin is an immunosuppressant thought to bind to cyclophilin in T-lymphocytes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79217-60-0. Pack Sizes: 25 mg; 50 mg. Product ID: HY-100731.
Cyclosporin
It is produced by the strain of Polypocladiurn inflatum. It has a strong immunosuppressive action, but also has anti-inflammatory and weak antifungal effects. The mechanism of immunosuppression is the combination of cyclosporin A and cyclosporin-binding protein in T cells, which inhibits the activity of Calcineurin, and then impedes the transposition of intracellular transcription factors into the nucleus, and inhibits the interleukin-2 transcription, resulting in immunosuppression. It is mainly used for kidney transplantation, bone marrow and heart transplantation, and is one of the most important immunosuppressive agents in clinical application. Uses: Enzyme inhibitors. Synonyms: Cyclosporins. Grade: >98%. CAS No. 79217-60-0.
Cyclosporin A
Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM[3]. Cyclosporin A also inhibits CD11a/CD18 adhesion[8]. Uses: Scientific research. Group: Natural products. Alternative Names: Cyclosporine A; Ciclosporin A; CsA. CAS No. 59865-13-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0579.
Cyclosporin A
Potent immunosuppressant (same as FK-506 and rapamycin). Forms a complex with cyclophilin. Inhibits the activity of the calcium/calmodulin-dependent protein phos- phatase 2B (PP2B; calcineurin). Prevents the dephosphorylation of nuclear factor of activated T cells (NFAT) transcription factor, leading to disruption of T cell activation. Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 (IL-2). Prevents rejection of transplanted organs. Anti-inflammatory compound in the treatment of several inflammatory skin diseases (e.g. atopic dermatitis) and with potential anti-rheumatic activity (rheumatoid arthritis). Antibacterial. Antifungal. Antiparasitic. Apoptosis inhibitor. Inhibits the mitochondrial permeability transition pore (MPTP) from opening, thus inhibiting cytochrome c release. NF-kappaB suppressor by induction of unfolded protein response (UPR). Anti-cancer compound. Apoptosis and autophagy inducer. Inhibits n Group: Biochemicals. Alternative Names: Antibiotic S 7481F1; Ciclosporin A; CsA; Cyclosporine; NSC 290193; Ramihyphin A; Sandimmun; Sandimmune; Neoral; Optimmune; Restasis; OL 27-400. Grades: Highly Purified. CAS No. 59865-13-3. Pack Sizes: 5g, 10g. US Biological Life Sciences.
Worldwide
Cyclosporin A-13C2,d4 Acetate
Labeled Cyclosporin A derivative. An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity. Group: Biochemicals. Alternative Names: Cyclosporine-13C2,d4 Acetate; Ciclosporin-13C2,d4 Acetate; Atopica-13C2,d4 Acetate; Sandimmun(e)-13C2,d4 Acetate; Neoral-13C2,d4 Acetate; Optimmune-13C2,d4 Acetate; Restasis-13C2,d4 Acetate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-13C2,d4 (Major).
An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Group: Biochemicals. Alternative Names: Cyclosporine-13C2,d4; Ciclosporin-13C2,d4; Atopica-13C2,d4; Sandimmun(e)-13C2,d4; Neoral-13C2,d4; Optimmune-13C2,d4; Restasis-13C2,d4. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Cyclosporin A 8-N-MeAla
Cyclosporin A 8-N-MeAla. Uses: For analytical and research use. Group: Impurity standards. CAS No. 108466-41-7. Molecular formula: C63H113N11O12. Mole weight: 1216.66. Catalog: APB108466417.
Cyclosporin A Acetate
A non-immunosuppressive analog. Group: Biochemicals. Alternative Names: 6-[(2S,3R,4R,6E)-3-(Acetyloxy)-4-methyl-2-(methylamino)-6-octenoic acid] Cyclosporin A; B 3-243; O-Acetyl-C91-cyclosporin A; O-Acetylcyclosporin A; SDZ 33-243. Grades: Highly Purified. CAS No. 83602-41-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-d4 Acetate (Major)
A non-immunosuppressive analog. Group: Biochemicals. Alternative Names: 6-[(2S,3R,4R,6E)-3-(Acetyloxy)-4-methyl-2-(methylamino)-6-octenoic-d4 acid] Cyclosporin A; B 3-243-d4; O-Acetyl-C91-cyclosporin A-d4; O-Acetylcyclosporin A-d4; SDZ 33-243-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-d4 (Major)
An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Group: Biochemicals. Alternative Names: Cyclosporine-d4; Ciclosporin-d4; Atopica-d4; Sandimmun(e)-d4; Neoral-d4; Optimmune-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-Derivative 1
Cyclosporin A-Derivative 1 is a metabolite of cyclosporine A. Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin phosphatase. Synonyms: Leu-Val-Leu-Ala-D-Ala-Leu-Leu-Val-Aaa-Abu-Sar.BF4; (7S,10S,13S,16S,19S,22R,25S,28S,31S,34S)-10-[(1R,2R,4E)-1-Acetoxy-2-methyl-4-hexen-1-yl]-7-ethyl-16,19,28-triisobutyl-13,31-diisopropyl-N,5,11,14,17,20,22,25,29,36-decamethyl-3,6,9,12,15,18,21,24,27,3 0,33-undecaoxo-2-oxa-5,8,11,14,17,20,23,26,29,32-decaazaheptatriacontan-34-aminium tetrafluoroborate. Grade: ≥98%. CAS No. 1487360-85-9. Molecular formula: C65H118BF4N11O14. Mole weight: 1364.50.
Cyclosporin A-Derivative 1 Free base
Cyclosporin A-Derivative 1 Free base is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporin A open ring; N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester; Cyclosporin A-Derivative 1 (Free base); Cyclosporin A seco(MeGly-MeLeu) Methyl Ester; Leu-Val-Leu-Ala-{d-Ala}-Leu-Leu-Val-{Aaa}-{Abu}-{Sar}; LVLA-{d-Ala}-LLV-{Aaa}-{Abu}-{Sar}. Grade: ≥95%. CAS No. 286852-20-8. Molecular formula: C65H117N11O14. Mole weight: 1276.69.
Cyclosporin A-Derivative 2
Cyclosporin A-Derivative 2 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: L-Valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester; Des(N-Methyl-leucyl) Cyclosporin A seco(MeGly-MeLeu) Methyl Ester; Glycine, L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester. Grade: ≥95%. CAS No. 156047-45-9. Molecular formula: C58H104N10O13. Mole weight: 1149.51.
Cyclosporin AM 1
A cyclosporine metabolite specifically inhibits growth of renal cells in culture. Group: Biochemicals. Alternative Names: 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin A; Cyclosporin A Metabolite 17; Cyclosporin Metabolite 17; M 17; OL 17. Grades: Highly Purified. CAS No. 89270-28-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin AM 3
Cyclosporin AM 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153049-50-4. Molecular formula: C62H111N11O13. Mole weight: 1218.63. Catalog: APB153049504.
Cyclosporin AM 4N
Cyclosporin AM 4N is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 9-L-Leucinecyclosporin A; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane Cyclic Peptide Deriv; AM 4N; Cyclosporin A Metabolite 21; M 21; OL 21; [Leu4]cyclosporin. Grade: ≥90% by HPLC. CAS No. 89270-23-5. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin AM 4N Acetate
Cyclosporin AM 4N Acetate is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: O-Acetyl-9-L-leucinecyclosporin A; O-Acetyl-cyclosporin A Metabolite 21. Grade: ≥95%. Molecular formula: C63H111N11O13. Mole weight: 1230.62.
Cyclosporin AM 7
Cyclosporin AM 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132362-39-1. Molecular formula: C61H109N11O13. Mole weight: 1204.61. Catalog: APB132362391.
Cyclosporin AM 9
Cyclosporin AM 9 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (4-Hydroxy-N-methyl-L-leucine)cyclosporine; 3-(4-Hydroxy-N-methyl-L-leucine)cyclosporin A; Cyclosporin A Metabolite 1; AM 9 (Peptide); OL 1; Cyclosporine metabolite M1; Cyclosporin metabolite AM9; Cyclosporine metabolite AM9; Cyclosporin A metabolite M1; (gamma-OH)MeLeu-9-cyclosporin; (gamma-OH)MeLeu-9-cyclosporine; (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-4-hydroxy-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-). Grade: ≥90% by HPLC. CAS No. 89270-25-7. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
Cyclosporin A (Standard)
Cyclosporin A (Standard) is the analytical standard of Cyclosporin A. This product is intended for research and analytical applications. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM [3]. Cyclosporin A also inhibits CD11a/CD18 adhesion [8]. Uses: Scientific research. Group: Natural products. CAS No. 59865-13-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0579R.
Cyclosporin B
An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Group: Biochemicals. Alternative Names: Ala2-cyclosporine; Antibiotic S 7481F2. Grades: Highly Purified. CAS No. 63775-95-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cyclosporin B
Cyclosporin B is a group of nonpolar cyclic oligopeptides with immunosuppressive activity. Cyclosporin B is used for the prevention of graft rejection in organ transplantation [1]. Uses: Scientific research. Group: Peptides. CAS No. 63775-95-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1973.
Cyclosporin B
Cyclosporin B is a minor analogue of the cyclosporin complex produced by Trichoderma. An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Synonyms: 7-L-Alaninecyclosporine A. Grade: ≥90% by HPLC. CAS No. 63775-95-1. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin C
?95% (HPLC), from Acremonium luzulae. Group: Fluorescence/luminescence spectroscopypharmaceutical toxicology. Alternative Names: 7-L-Threonine-cyclosporin A, Cyclosporin C, Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl], 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane, cyclic peptide deriv.,Ciclosporin C.
Cyclosporin C
A group of nonpolar cyclic oligopeptides with immunosupppressant activity. Group: Biochemicals. Alternative Names: Thr2-cyclosporine. Grades: Highly Purified. CAS No. 59787-61-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cyclosporin C
Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal , antiviral, and immunosuppressant properties. Cyclosporin C is active against isolates of B. cinerea , A. niger , and Alternaria , Mucor , and Penicillium species (MICs=0.1-5 μg/ml). Uses: Scientific research. Group: Signaling pathways. CAS No. 59787-61-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6027.
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