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D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC 50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Erythrosphingosine; erythro-C18-Sphingosine; trans-4-Sphingenine. CAS No. 123-78-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101047.
D-erythro-Sphingosine is a natural isomer of sphingosine and acts as an inhibitor of protein kinase C and calmodulin-dependent enzymes with no effects on protein kinase A or myosin light chain kinase. It may stimulate mast cells by activation of protein kinase C. Synonyms: Sphingosine (d18:1); sphingosine; D-Sphingosine; 4-Sphingenine; 2S, 3R(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol; (2S,3R,4E)-2-amino-1,3-octadec-4-enediolsphing-4-enine. Grade: >99%. CAS No. 123-78-4. Molecular formula: C18H37NO2. Mole weight: 299.49.
D-erythro-Sphingosine-13C2,D2
D-erythro-Sphingosine-13C2,D2. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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D-Erythro-Sphingosine 1-Phosphate
D-Erythro-Sphingosine 1-Phosphate. Group: Biochemicals. Grades: Highly Purified. CAS No. 26993-30-6. Pack Sizes: 1mg, 2mg. US Biological Life Sciences.
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D-erythro-Sphingosine-1-Phosphate-13C2,D2
A labeled putative lipid second messenger; found to inhibit cellular mobility of melanoma cells at very low concentrati. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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D-erythro-Sphingosine-1-Phosphate (SPN-1-P)
A putative lipid second messenger; found to inhibit cellular mobility of melanoma cells at very low concentrati. Group: Biochemicals. Alternative Names: SPN-1-P. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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D-erythro-Sphingosine-d7
D-erythro-Sphingosine-d 7 is the deuterium labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Erythrosphingosine-d7; erythro-C18-Sphingosine-d7; trans-4-Sphingenine-d7. CAS No. 1246304-34-6. Pack Sizes: 500 μg. Product ID: HY-101047S.
D-erythro-Sphingosine hydrochloride
D-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specific TRPM3 activator. D-erythro-Sphingosine also induces retinoblastoma protein dephosphorylation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Erythrosphingosine hydrochloride; erythro-C18-Sphingosine hydrochloride; trans-4-Sphingenine hydrochloride. CAS No. 2673-72-5. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W089922.
Caged SPP provides a method to elevate intracellular level of SPP upon ultraviolet irradiation and thus can be utilized as a new tool in studies of SPP-mediated intracellular events. Group: Biochemicals. Alternative Names: Caged SPP. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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N-Biotinyl D-erythro-Sphingosine
A biotinylated substrate conjugate used for performing ELISA on water-soluble ligands. Group: Biochemicals. Alternative Names: (3aS,4S,6aR)-. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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N-Biotinyl D-erythro-Sphingosine-1-phosphate
A biotinylated substrate conjugate used for performing ELISA on water-soluble ligands. Used for ceramide phosphate sphingosine synthesis. Group: Biochemicals. Alternative Names: (3aS,4S,6aR)-. Grades: Highly Purified. CAS No. 1093733-24-4. Pack Sizes: 5mg. US Biological Life Sciences.
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N-Biotinyl D-erythro-Sphingosine-1-phosphate
N-Biotinyl D-erythro-Sphingosine-1-phosphate. Uses: A biotinylated substrate conjugate used for performing elisa on water-soluble ligands. used for ceramide phosphate sphingosine synthesis. Synonyms: (3aS,4S,6aR)-. Grade: 95%. CAS No. 1093733-24-4. Molecular formula: C28H52N3O7PS. Mole weight: 605.77.
N-Boc-1-pivaloyl D-erythro-sphingosine
N-Boc-1-pivaloyl D-erythro-sphingosine. Group: Biochemicals. Grades: Highly Purified. CAS No. 342649-71-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C28H53NO5. US Biological Life Sciences.
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N-Boc-1-pivaloyl D-erythro-sphingosine
N-Boc-1-pivaloyl D-erythro-sphingosine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CTK8E7759, 342649-71-2, N-Boc-1-pivaloyl-D-erythro-sphingosine. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 342649-71-2. Molecular formula: C28H53NO5. Mole weight: 483.72. Purity: 0.96. IUPACName: [(2R,3S)-3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]octadec-4-enyl] 2,2-dimethylpropanoate. Canonical SMILES: CCCCCCCCCCCCCC=CC(C(COC(=O)C(C)(C)C)NC(=O)OC(C)(C)C)O. Product ID: ACM342649712. Alfa Chemistry ISO 9001:2015 Certified.
N-(NBD-aminohexanoyl) D-erythro-sphingosine
N-(NBD-aminohexanoyl) D-erythro-sphingosine. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanamide; N- [ (7-Nitrobenz-2-oxa-1, 3-diazol-4-yl) aminocaproyl] sphingosine; NBD-C 6Cer. Grades: Highly Purified. CAS No. 94885-02-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C30H49N5O6. US Biological Life Sciences.
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Sphingosine (D-erythro-Sphingosine)
Selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes; natural isomer of sphingosine. Group: Biochemicals. Alternative Names: (2S,3R,4E)-2-Aminooctadec-4-ene-1,3-diol; trans-D-erythro-2-Amino-4-octadecene-1,3-diol; 4-Sphingenine; D-erythro-Sphingosine. Grades: Highly Purified. CAS No. 123-78-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??NO?, Molecular Weight: 299.49. US Biological Life Sciences.
The biomedical product, 18:0(2R-OH) Sulfo GalCer Ammonium salt, is a potent agent in the fight against cancer. Specifically designed as an activator in immunotherapy, this mighty compound provides a means to target and treat a range of cancers including melanoma, leukemia, and lymphoma. With a molecular conformation that allows for binding to natural killer T cells, clinical research has demonstrated a positive immune response against cancer cells. Synonyms: 3-O-sulfo-D-galactosyl-β-1,1'-N-[2''(R)-hydroxystearoyl]-D-erythro-sphingosine (ammonium salt); Ammonium (2S,3R,4E)-3-hydroxy-2-{[(2R)-2-hydroxyoctadecanoyl]amino}-4-octadecen-1-yl 3-O-sulfonato-β-D-threo-hexopyranoside; Octadecanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-[[(3-O-sulfo-β-D-galactopyranosyl)oxy]methyl]-3-heptadecen-1-yl]-, ammonium salt (1:1), (2R)-. Grade: >99%. CAS No. 2260670-26-4. Molecular formula: C42H84N2O12S. Mole weight: 841.19.
18:0(2S-OH) Sulfo GalCer Ammonium salt, a synthetic compound employed in biomedical research, has the capacity to serve as a potent therapeutic agent for the treatment of various malignancies- specifically leukemia and lymphoma. Boasting versatile therapeutic potential, it has been shown to exhibit anti-inflammatory properties, and has exciting potential for the treatment of autoimmune diseases like multiple sclerosis. With its staggering attributes as a sulfo glycolipid, this intriguing compound holds tremendous promise and warrants thorough exploration in the realm of drug development. Synonyms: 3-O-sulfo-D-galactosyl-β-1,1'-N-[2''(S)-hydroxystearoyl]-D-erythro-sphingosine (ammonium salt); Ammonium (2S,3R,4E)-3-hydroxy-2-{[(2S)-2-hydroxyoctadecanoyl]amino}-4-octadecen-1-yl 3-O-sulfonato-β-D-threo-hexopyranoside; Octadecanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-[[(3-O-sulfo-β-D-galactopyranosyl)oxy]methyl]-3-heptadecen-1-yl]-, ammonium salt (1:1), (2S)-. Grade: >99%. CAS No. 2260670-28-6. Molecular formula: C42H84N2O12S. Mole weight: 841.19.
b-D-Galactopyranoside,(2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: O-Galactosylsphingosine; Psychosine from bovine brain; Galactosylsphingosine; D-GALACTOSYL-B1-1 SPHINGOSN; LYSO-CEREBROSIDE; PSYCHOSIN; PSYCHOSINE; LYSO-CERAMIDEGALACTOSIDE; D-galactosyl-ß1-1-D-erythro-sphingosine; 1-B-D-GALACTOSYLSPHINOGOSINE. Product Category: Heterocyclic Organic Compound. Appearance: White powder. CAS No. 2238-90-6. Molecular formula: C24H47NO7. Mole weight: 461.63. Purity: 0.96. IUPACName: (2R,3R,4S,5R,6R)-2-[(E)-2-amino-3-hydroxyoctadec-4-enoxy]-6-(hydroxymethyl)oxane-3,4,5-triol. Density: 1.14 g/cm³. Product ID: ACM2238906. Alfa Chemistry ISO 9001:2015 Certified.
b-D-Galactosylsphingosine
It is a cationic lysosphingolipid that has neuroprotective effects against quisqualate. Synonyms: D-galactosyl-β1-1'-D-erythro-sphingosine; Galactosyl(β) Sphingosine (d18:1); Psychosine1-β-galactosyl-sphing-4-enine; Psychosine; (2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl β-D-Galactopyranoside; Galactosylsphingosine; erythro-Psychosine; (E)-DL-erythro-2-Amino-3-hydroxy-4-octadecenyl β-D-Galactopyranoside; Sphingosine galactoside; 1-beta-D-galactosphingosine. Grade: >99%. CAS No. 2238-90-6. Molecular formula: C24H47NO7. Mole weight: 461.63.
Biotin S1P
Sphingosine 1-phosphate biotin is a S1P analog with natural erythro stereochemistry labeled at the terminus of the alkyl chain with biotin. Biotin S1P is produced by the phosphorylation of biotinyl sphingosine by recombinant human sphingosine kinase 1 and 2 (hSK1 and hSK2). Synonyms: omega-biotinyl D-erythro-sphingosine-1-phosphate; (2S,3R,4E)-2-Azaniumyl-3-hydroxy-18-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)octadec-4-en-1-yl hydrogen phosphate. Grade: >99%. CAS No. 799812-63-8. Molecular formula: C28H53N4O7PS. Mole weight: 620.78.
It is a modified lipid containing an omega-terminal azide. In the presence of a coppery(Cu)-containing catalyst, the terminal azide group can be used for highly specific binding reactions with alkyne-containing reagents, known as ''click chemistry''. Synonyms: D-Galactosyl-β-1,1'-N-(6''-azidohexanoyl)-D-erythro-sphingosine; C6(6-azido) Galactosyl(β) Ceramide; 6-Azido-N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]hexanamide. Grade: >99%. CAS No. 2260670-20-8. Molecular formula: C30H56N4O8. Mole weight: 600.79.
C6(6-azido) GluCer
It is a modified lipid containing an omega-terminal azide. In the presence of a coppery(Cu)-containing catalyst, the terminal azide group can be used for highly specific binding reactions with alkyne-containing reagents, known as ''click chemistry''. Synonyms: D-Gluctosyl-β-1,1'-N-(6''-azidohexanoyl)-D-erythro-sphingosine; C6(6-azido) Gluctosyl(β) Ceramide; 6-Azido-N-[(1S,2R,3E)-1-[(β-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]hexanamide. Grade: >99%. CAS No. 2260670-21-9. Molecular formula: C30H56N4O8. Mole weight: 600.79.
C6(6-azido) LacCer
It is a modified lipid containing an omega-terminal azide. In the presence of a coppery(Cu)-containing catalyst, the terminal azide group can be used for highly specific binding reactions with alkyne-containing reagents, known as ''click chemistry''. Synonyms: D-Lactosyl-β-1,1'-N-(6''-azidohexanoyl)-D-erythro-sphingosine; C6(6-azido) Lactosyl(β) Ceramide; 6-Azido-N-[(1S,2R,3E)-1-[[(4-O-β-D-galactopyranosyl-β-D-glucopyranosyl)oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]hexanamide. Grade: >99%. CAS No. 2260670-19-5. Molecular formula: C36H66N4O13. Mole weight: 762.93.
D-Erythro-c8 ceramine
D-Erythro-c8 ceramine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-OCTYLSPHINGOSINE;D-ERYTHRO-CERAMINE C8;C-8 CERAMINE;2-OCTYLAMINO-4-OCTADECEN-1,3-DIOL;D-erythro-Sphingosine, N-Octyl-;N-Octylsphinegosine;N-Octyl-D-sphingosine. Product Category: Heterocyclic Organic Compound. CAS No. 170926-06-4. Molecular formula: C26H53NO2. Mole weight: 411.7. Product ID: ACM170926064. Alfa Chemistry ISO 9001:2015 Certified.
erythro-ω-Amino Sphingosine Biotinamide
Biotin Sphingosine is a derivative of sphingosine. It contains a biotin moiety linked to the ω-terminal of its fatty-acid chain. Biotin Sphingosine plays a key role in identifying sphingosine interaction with acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A). It is used in an assay for sphingosine kinase activity using biotinylated sphingosine and streptavidin-coated membranes. Synonyms: omega-biotinyl D-erythro-sphingosine; Biotin Sphingosine; (3aS,4S,6aR)-N-[(14E,16R,17S)-17-Amino-16,18-dihydroxy-14-octadecen-1-yl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide. Grade: >99%. CAS No. 752987-57-8. Molecular formula: C28H52N4O4S. Mole weight: 540.80.
Sphingosine-1-phosphate (d17:1)
Sphingosine-1-phosphate d17:1 (D-erythro-Sphingosine-C17-1-phosphate) is a derivative of ceramide. Sphingosine-1-phosphate d17:1 can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-erythro-Sphingosine-C17-1-phosphate. CAS No. 474923-27-8. Pack Sizes: 1 mg. Product ID: HY-141630.