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Nα-Boc-D-histidine is an N-Boc-protected form of D-Histidine. D-Histidine is the unnatural, biologically inactive isomer of L-Histidine. D-histidine is known to inhibit cell division, and is also used by certain types of bacteria (such as Escherichia coli) as a source of L-Histidine. Synonyms: Boc-D-His-OH; 2-[(tert-Butoxycarbonyl)amino]-3-(1H-imidazol-4-yl)propanoic acid; N-(tert-Butoxycarbonyl)-D-histidine; NAlpha-Boc-D-histidine; BOC-D-HISTIDINE; N(a)-Boc-D-histidine. Grades: ≥ 97%. CAS No. 50654-94-9. Molecular formula: C11H17N3O4. Mole weight: 255.29.
Synonyms: benzoyl-D-histidine; D-Histidine, N-benzoyl-. Grades: >95% by HPLC. CAS No. 127063-22-3. Molecular formula: C13H13N3O3. Mole weight: 259.26.
N-Boc-1-(phenylmethyl)-D-histidine
N-Boc-1-(phenylmethyl)-D-histidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: D-Histidine,N-[(1,1-dimethylethoxy)carbonyl]-1-(phenylmethyl)-;N-BOC-1-PHENYLMETHYL-D-HISTIDINE;N-[(1,1-Dimethylethoxy)carbonyl]-1-phenylmethyl-D-histidine. Product Category: Heterocyclic Organic Compound. CAS No. 65717-64-8. Molecular formula: C18H23N3O4. Mole weight: 345.39. Product ID: ACM65717648. Alfa Chemistry ISO 9001:2015 Certified.
Nim-Trityl-D-histidine
Nim-Trityl-D-histidine is used as a reagent in solid-phase synthesis and screening of peptides as catalysts for asymmetric induction of desymmetrization of bis(phenol)s. Synonyms: D-His(Trt)-OH; (2R)-2-amino-3-(1-tritylimidazol-4-yl)propanoic acid; Nim-Trityl-D-histidine; D-Histidine,1-(triphenylmethyl); H-D-His(Trt)-OH. Grades: ≥ 99% (HPLC). CAS No. 199119-46-5. Molecular formula: C25H23N3O2. Mole weight: 397.48.
Standard building block for introduction of D-histidine amino-acid residues by Boc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Boc-D-His-OH, N-α-t.-Boc-D-histidine. Product Category: Amino Acids. CAS No. 50654-94-9. Mole weight: 255.27. Product ID: ACM50654949. Alfa Chemistry ISO 9001:2015 Certified.
(Des-Gly10,D-His2,D-Leu6,Pro-NHEt9)-LHRH is an impurity of Leuprolide, which is a synthetic nonapeptide analog of gonadotropin-releasing hormone used as an antineoplastic agent, a gonadotropin-releasing hormone agonist, and an anti-estrogen. Synonyms: (D-His2)-Leuprolide; 2-D-Histidine-6-D-leucine-9-(N-ethyl-L-prolinamide)-1-9-luteinizing Hormone-releasing Factor (swine); Leuprolide Acetate EP Impurity B; L-pyroglutamyl-D-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamide; H-Pyr-D-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt; 5-Oxo-L-prolyl-D-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide. Grades: 95%. CAS No. 112642-11-2. Molecular formula: C59H84N16O12. Mole weight: 1209.40.
(Des-Gly10,D-His2,D-Ser4,D-Leu6,Pro-NHEt9)-LHRH
(Des-Gly10,D-His2,D-Ser4,D-Leu6,Pro-NHEt9)-LHRH is the impurity F of the Leuprorelin. Synonyms: (D-His2,D-Ser4)-Leuprolide; Pyr-D-His-Trp-D-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt; Leuprolide Acetate EP Impurity F; Leuprorelin EP Impurity F; L-Prolinamide, 5-oxo-L-prolyl-D-histidyl-L-tryptophyl-D-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-; [2-D-Histidine,4-D-serine]leuprorelin; (S)-N-Ethyl-1-(((S)-5-oxopyrrolidine-2-carbonyl)-D-histidyl-L-tryptophyl-D-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)pyrrolidine-2-carboxamide. Grades: ≥95%. CAS No. 1872435-00-1. Molecular formula: C59H84N16O12. Mole weight: 1209.42.
(D-His2,D-Ser(tBu)6,Azagly10)-LHRH
(D-His2,D-Ser(tBu)6,Azagly10)-LHRH is the impurity G of the Goserelin. Synonyms: (D-His2)-Goserelin; Pyr-D-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2; L-pyroglutamyl-D-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-N'-carbamoyl-L-prolinehydrazide; Goserelin EP Impurity G; Goserelin Impurity 7; [2-D-Histidine]goserelin; (2S)-N-[(2R,5S,8S,11S,14R,17S,20S)-25-Amino-20-({(2S)-2-[(2-carbamoylhydrazino)carbonyl]-1-pyrrolidinyl}carbonyl)-11-(4-hydroxybenzyl)-8-(hydroxymethyl)-1-(1H-imidazol-5-yl)-25-imino-5-(1H-indol-3-ylmethyl)-17-isobutyl-14-{[(2-methyl-2-propanyl)oxy]methyl}-3,6,9,12,15,18-hexaoxo-4,7,10,13,16,19,24-heptaazapentacosan-2-yl]-5-oxo-2-pyrrolidinecarboxamide. Grades: ≥95%. CAS No. 1926163-37-2. Molecular formula: C59H84N18O14. Mole weight: 1269.41.
D-Histidine methyl ester is a protected form of D-Histidine. D-Histidine is the unnatural, biologically inactive isomer of L-Histidine. D-histidine is known to inhibit cell division, and is also used by certain types of bacteria (such as Escherichia coli) as a source of L-Histidine. Synonyms: D-Histidine methyl ester dihydrochloride; (R)-methyl 2-amino-3-(1H-imidazol-4-yl)propanoate dihydrochloride; H-D-His-OMe 2HCl; D-HISTIDINE METHYLESTER DIHYDROCHLORIDE; H-D-His-OMe 2HCl; methyl (2R)-2-amino-3-(1H-imidazol-5-yl)propanoate dihydrochloride; H D His OMe 2HCl. Grades: ≥ 98% (HPLC). CAS No. 4467-54-3. Molecular formula: C7H11N3O2·2HCl. Mole weight: 242.11.
D-His-OMe·2HCl
D-His-OMe·2HCl. Group: Biochemicals. Alternative Names: D-Histidine methyl ester dihydrochloride. Grades: Highly Purified. CAS No. 4467-54-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C7H11N3O2·2HCl. US Biological Life Sciences.
Worldwide
Fmoc-D-His(Clt)-OH
Building block for introduction of D-histidine by Fmoc SPPS. The Clt group is more stable to acid than Trt and its use avoids the formation of partially protected histidine peptides during the preparation of protected fragments. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-D-His(Clt)-OH, N-α-Fmoc-N-im-2-chlorotrityl-D-histidine. Product Category: Amino Acids. CAS No. 1272755-56-2. Molecular formula: C40H32ClN3O4. Mole weight: 654.15. IUPACName: (2R)-3-[1-[(2-chlorophenyl)-diphenylmethyl]imidazol-4-yl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid. Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=C(N=C4)CC(C(=O)O)NC(=O)OCC5C6=CC=CC=C6C7=CC=CC=C57. Product ID: ACM1272755562. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-D-His(Trt)-OH
Standard building block of introduction of D-histidine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-N(im)-trityl-D-histidine. Product Category: Amino Acids. CAS No. 135610-90-1. Molecular formula: C40H33N3O4. Mole weight: 619.71. Canonical SMILES: OC(=O)[C@@H](Cc1cn(cn1)C(c2ccccc2)(c3ccccc3)c4ccccc4)NC(=O)OCC5c6ccccc6-c7ccccc57. Product ID: ACM135610901. Alfa Chemistry ISO 9001:2015 Certified. Categories: (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanoic acid.
An acetate salt obtained by combining histrelin with acetic acid. The amount of acetic acid present can vary and a variable amount of water may be present. Histrelin acetate is used as a subcutaneous hydrogel implant for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty. Synonyms: 1-9-Luteinizing hormone-releasing factor (swine), 6-[1-(phenylmethyl)-D-histidine]-9-(N-ethyl-L-prolinamide)-, acetate (1:x); 1-9-Luteinizing hormone-releasing factor (swine), 6-[1-(phenylmethyl)-D-histidine]-9-(N-ethyl-L-prolinamide)-, acetate (salt); Supprelin; H-Pyr-His-Trp-Ser-Tyr-D-His(1-Bn)-Leu-Arg-Pro-NHEt.xCH3CO2H; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-L-proline ethylamide acetic acid. Grades: >98%. CAS No. 220810-26-4. Molecular formula: C66H86N18O12.xC2H4O2. Mole weight: 1323.50 (free base).
2-Amino-3-(3H-imidazol-4-yl)-propionic acid ethyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (R)-1-ETHOXYCARBONYL-2-(3H-IMIDAZOL-4-YL)-ETHYLAMINE HCL;2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPIONIC ACID ETHYL ESTER. Product Category: Heterocyclic Organic Compound. CAS No. 184295-36-1. Molecular formula: C8H13N3O2. Mole weight: 183.21. Product ID: ACM184295361. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ethyl D-histidinate.