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Daunomycin is an intermediate of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 8-Acetyl-6,10,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 8-Acetyl-6,10,11-trihydroxy-1-methoxytetracene-5,12-dione; 8-Acetyl-5,12-dihydro-6,10,11-trihydroxy-1-methoxynaphthacene-5,12-dione; 5,12-Naphthacenedione, 8-acetyl-6,10,11-trihydroxy-1-methoxy-; Daunorubicin Impurity 5. Grades: ≥95%. CAS No. 20982-41-6. Molecular formula: C21H14O7. Mole weight: 378.33.
Daunomycinone
Daunomycinone. Group: Biochemicals. Alternative Names: (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy- -5,12-naphthacenedione; (+)-Daunomycinone; Daunomycin aglicone; Daunorubicinone. Grades: Highly Purified. CAS No. 21794-55-8. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C21H18O8. US Biological Life Sciences.
Worldwide
Daunomycinone
Daunomycinone (NSC-109351) is a metabolite of daunomycin. Daunomycin is an antibiotic with antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC-109351. CAS No. 21794-55-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114658.
Daunomycinone-d3
The main metabolite of labeled Daunorubicin (DNR). Group: Biochemicals. Alternative Names: (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy- -5,12-naphthacenedione-d3; (+)-Daunomycinone-d3; Daunomycin Aglicone-d3; Daunomycinon-d3; Daunorubicin Aglycone-d3; Daunorubicinone-d3; Leukaemomycinone C-d3; NSC 109351-d3. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Daunomycinone derivative. Used in the preparation of anti-tumor agents. Group: Biochemicals. Alternative Names: (8S-cis) -7, 8, 9, 10-Tetrahydro-6, 8, 10, 11-tetrahydroxy-1-methoxy-8- [ [ (4-methoxyphenyl) diphenylmethoxy] acetyl] -5, 12-naphthacenedione. Grades: Highly Purified. CAS No. 59326-04-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
14-Bromodaunomycinone
Daunomycinone derivatieve. Group: Biochemicals. Alternative Names: (8S,10S)-8-(2-Bromoacetyl)-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione; (8S,cis)-8-(2-Bromoacetyl)-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione. Grades: Highly Purified. CAS No. 29742-69-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
14-O-Acetyldaunomycinone
Protected Daunomycinone, the main metabolite of Daunorubicin (DNR). Group: Biochemicals. Alternative Names: 14-O-Acetyladriamycinone; (8S,10S)-8-[2-(Acetyloxy)acetyl]-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione; (8S,cis)-8-[2-(Acetyloxy)acetyl]-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione. Grades: Highly Purified. CAS No. 29984-41-6. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
4-Demethyl Daunomycinone
4-Demethyl Daunomycinone. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (8S,10S)-8-acetyl-1,6,8,10,11-pentahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione. CAS No. 52744-22-6. Molecular Formula: C20H16O8. Mole Weight: 384.34. Catalog: APB52744226.
4-Demethyl Daunomycinone
A metabolite Daunorubicin. Group: Biochemicals. Alternative Names: (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-1,6,8,10,11-pentahydroxy-5,12-naphthacenedione; (+)-Carminomycinone; 4-Demethoxy-4-hydroxydaunomycinone; 4-O-Demethyldaunomycinone; Carminomycinone. Grades: Highly Purified. CAS No. 52744-22-6. Pack Sizes: 1mg. US Biological Life Sciences.
(2S-?cis) ?-1, ?2, ?3, ?4, ?6, ?11-?Hexahydro-?2, ?4, ?5, ?12-?tetrahydroxy-?7-?methoxy-?6, ?11-?dioxo-2-?Naphthacene carboxyli?c Acid Methyl Ester is an intermediate in synthesizing Bis-anhydro-Daunomycinone Carboxylic Acid (B407000), a Daunomycinone (D193850) derivative. Group: Biochemicals. Grades: Highly Purified. CAS No. 58199-99-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H18O9. US Biological Life Sciences.
Worldwide
4'-epi-Daunorubicin Hydrochloride
4'-epi-Daunorubicin Hydrochloride is an impurity of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxynaphthacene-5,12-dione hydrochloride; (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Hydrochloride; (8S-cis)-4'-Epidaunorubicin Hydrochloride; 4'-epi-Daunomycin Hydrochloride; NSC 249333; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranoside hydrochloride (1:1). Grades: 95%. CAS No. 56390-08-0. Molecular formula: C27H29NO10.HCl. Mole weight: 563.99.
aklaviketone reductase
The enzyme is involved in the synthesis of the aklavinone aglycone, a common precursor for several anthracycline antibiotics including aclacinomycins, daunorubicin and doxorubicin. The enzyme from the Gram-negative bacterium Streptomyces sp. C5 produces daunomycin. Group: Enzymes. Synonyms: dauE (gene name); aknU (gene name). Enzyme Commission Number: EC 1.1.1.362. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0279; aklaviketone reductase; EC 1.1.1.362; dauE (gene name); aknU (gene name). Cat No: EXWM-0279.
Daunorubicin
Daunorubicin (Daunomycin) is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin inhibits DNA and RNA synthesis. Daunorubicin is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin is also an anthracycline antibiotic. Daunorubicin can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-;Daunomycin. Product Category: Inhibitors. CAS No. 20830-81-3. Molecular formula: C27H29NO10. Mole weight: 527.52. Product ID: ACM20830813. Alfa Chemistry ISO 9001:2015 Certified.
Daunorubicin EP Impurity B
Daunorubicinol, a metabolite of Daunorubicin, is an anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Synonyms: 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-((1S)-1-hydroxyethyl)-1-methoxy-, (8S,10S)-; 13-Dihydrodaunorubicin; Duborimycin; Leukaemomycin D; Daunorubicin EP Impurity B (Mixture of Diastereomers); (13S)-13-Dihydrodaunorubicin; (1S,3S)-3,5,12-Trihydroxy-3-[(1S)-1-hydroxyethyl]-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; Daunomycinol; Dihydrodaunomycin; Antibiotic 20-798RP; Daunorubicinol. Grades: >95%. CAS No. 28008-55-1. Molecular formula: C27H31NO10. Mole weight: 529.54.
Daunorubicin hydrochloride
Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor [1] [2] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Daunomycin hydrochloride; RP 13057 hydrochloride; Rubidomycin hydrochloride. CAS No. 23541-50-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13062.
Daunorubicin hydrochloride
Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM. Uses: Adcs cytotoxin. Synonyms: RP 13057 Hydrochloride; Daunomycin; RP13057 Hydrochloride; RP-13057 Hydrochloride; Rubidomycin hydrochloride. Grades: >98%. CAS No. 23541-50-6. Molecular formula: C27H30ClNO10. Mole weight: 563.98.
Daunorubicin Hydrochloride (Mixture of Diastereomers)
Daunorubicin Hydrochloride (Mixture of Diastereomers). Group: Biochemicals. Alternative Names: (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Hydrochloride; (8S-cis)-Daunomycin Hydrochloride; Cerubidine; Daunoblastin; Daunomycin Chlorohydrate; ?NDC 0082-4155; Ondena; RP 13057 Hydrochloride; Rubidomycin Hydrochloride. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Idarubicinone
Idarubicinone is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 4-demethoxy daunomycinone; (7S,9S)-9-acetyl-6,7,9,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione; 4-Demethoxydaunomycinone; Idarubicin aglycone; (+)-4-Demethoxydaunomycinone; 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-, (7S-cis)-; (+)-Idarubicinone; (8S,10S)-7,8,9,10-Tetrahydro-6,8,10,11-tetrahydroxy-8-acetyl-5,12-naphthacenedione. Grades: ≥95%. CAS No. 60660-75-5. Molecular formula: C20H16O7. Mole weight: 368.34.
Zorubicin
Zorubicin is a benzoyl-hydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Synonyms: RP-22050; RP 22050; RP22050; Zorubicine; N'- (1-{ (2S, 4S) -4-[ (3-Amino-2, 3, 6-trideoxy-α -L-lyxo-hexopyranosyl) oxy]-2, 5, 12-trihydroxy-7-methoxy-6, 11-dioxo-1, 2, 3, 4, 6, 11-hexahydro-2-tetracenyl}ethylidene) benzohydrazide; Rubidazone; Benzoic acid hydrazide, 3-hydrazone with daunorubicin; Benzoic acid, (1-(4-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl)ethylidene)hydrazide, (2S-cis)-; Benzoic acid, 2-[1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide; Daunomycin benzoylhydrazone; MCMC 4222; Rubidazon. Grades: ≥95%. CAS No. 54083-22-6. Molecular formula: C34H35N3O10. Mole weight: 645.66.
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