Diacylglycerol Suppliers USA
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Product | Description | |
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1,2-Dilauroyl-sn-glycerol Quick inquiry Where to buy Suppliers range | 1,2-Dilauroyl-sn-glycerol is a saturated diacylglycerol (DAG) with lauric acid. DAGs are commonly used as emulsifiers in pharmaceutical manufacturing and food industry. DAGs act as second messenger signaling lipid and activate PKC. Synonyms: Dodecanoic acid, 1,1'-[(1S)-1-(hydroxymethyl)-1,2-ethanediyl] ester; Dodecanoic acid, (1S)-1-(hydroxymethyl)-1,2-ethanediyl ester; Dodecanoic acid, 1-(hydroxymethyl)-1,2-ethanediyl ester, (S)-; sn-1,2-Dilauroylglycerol; (S)-3-hydroxypropane-1,2-diyl didodecanoate. Grades: >99%. CAS No. 60562-15-4. Molecular formula: C27H52O5. Mole weight: 456.70. | |
1,2-Dilinoleoylglycerol-d5 Quick inquiry Where to buy Suppliers range | 1,2-Dilinoleoylglycerol-d5 is labelled 1,2-Dilinoleoylglycerol (D460605) which is a diacylglycerol from palm oil deodorizer distillate. It can be used as an Immunostimulant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C39H63D5O5, Molecular Weight: 621.99. US Biological Life Sciences. | Worldwide |
1,2-Dimyristoyl-sn-glycerol-3-(5?-diphosphocytidine) Dipotassium Salt Quick inquiry Where to buy Suppliers range | 1,2-Dimyristoyl-sn-glycerol-3-(5?-diphosphocytidine) is a derivative of 1,2-Dimyristoyl-sn-glycerol (D479825) which is a saturated diacylglycerol (DAG). 1,2-Dimyristoyl-sn-glycerol is a possible weak second messenger for the activation of the PKC. Group: Biochemicals. Grades: Highly Purified. CAS No. 138879-82-0. Pack Sizes: 500ug, 1mg. Molecular Formula: C40H71K2N3O15P2, Molecular Weight: 974.15. US Biological Life Sciences. | Worldwide |
1,3-Dioleoyl-rac-glycerol Quick inquiry Where to buy Suppliers range | 1,3-Dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at the sn-1 and sn-3 positions. It activates protein kinase C (PKC) by approximately 30% when used at a concentration of 50 μM. It was used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents. Synonyms: 2-Hydroxy-1,3-propanediyl dioleate; Glycerol 1,3-dioleate; 1,3-Diolein. Grades: ≥98%. CAS No. 2465-32-9. Molecular formula: C39H72O5. Mole weight: 620.99. | |
1,3-Dipalmitoyl-rac-glycerol Quick inquiry Where to buy Suppliers range | 1,3-Dipalmitoyl-rac-glycerol is a diacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions. It activates protein kinase C α (PKCα) in vitro (Ka = 3.8 μM). 1,3-Dipalmitoyl-rac-glycerol (0.25-2 μM) inhibits apoptosis and production of reactive oxygen species (ROS) and pro-inflammatory mediators induced by oxygen-glucose deprivation and reperfusion (OGD/R) in SH-SY5Y neuroblastoma cells. An acyl acceptor for the unspecific bifunctional wax ester synthase/acyl-CoA:Diacylglycerol acyltransferase. Synonyms: 1,3-Dipalmitin; Dipalmitin; 1,3-Dipalmitoyl-glycerol; Glyceryl 1,3-dipalmitate. Grades: ≥98%. CAS No. 502-52-3. Molecular formula: C35H68O5. Mole weight: 568.91. | |
1-Oleoyl lysophosphatidic acid Quick inquiry Where to buy Suppliers range | 1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase. Synonyms: 1-Oleoyl-sn-glycerol 3-phosphate; Oleoyl LPA; 18:1 LPA; 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate; LysoPA(18:1). Grades: ≥95%. CAS No. 65528-98-5. Molecular formula: C21H41O7P. Mole weight: 436.50. | |
1-Palmito-2-stearin Quick inquiry Where to buy Suppliers range | 1-Palmito-2-stearin is a diacylglycerol used to increase the activity of the ARF1 GTPase-activating protein on membrane-bound ARF1GTP. Group: Biochemicals. Grades: Highly Purified. CAS No. 20296-26-8. Pack Sizes: 10mg, 100mg. Molecular Formula: C37H72O5. US Biological Life Sciences. | Worldwide |
1-Palmito-2-stearin-d5 Quick inquiry Where to buy Suppliers range | 1-Palmito-2-stearin-d5 is labelled 1-Palmito-2-stearin (P144980) which is a diacylglycerol used to increase the activity of the ARF1 GTPase-activating protein on membrane-bound ARF1GTP. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C37H67D5O5, Molecular Weight: 602. US Biological Life Sciences. | Worldwide |
1-Palmitoyl-2-oleoyl-rac-glycerol-d5 Quick inquiry Where to buy Suppliers range | 1-Palmitoyl-2-oleoyl-rac-glycerol-d5 is labelled 1-Palmitoyl-2-oleoyl-rac-glycerol (P160950) which is a monounsaturated diacylglycerol used to increase the activity of the ARF1 GTPase-activating protein on membrane-bound ARF1GTP. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C37H65D5O5, Molecular Weight: 599.98. US Biological Life Sciences. | Worldwide |
1-Palmitoyl-d9-2-Palmitoyl-sn-glycerol Quick inquiry Where to buy Suppliers range | 1-Palmitoyl-d9-2-palmitoyl-sn-glycerol is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycerol by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that contains palmitic acid at the sn-1 and sn-2 positions. It activates protein kinase C (PKC) by 15% when used at a concentration of 25 μM. Synonyms: 1,2-Dipalmitoyl-sn-glycerol-d9; DG(16:0-d9/16:0/0:0). Grades: ≥99% atom D. CAS No. 1872379-48-0. Molecular formula: C35H59D9O5. Mole weight: 578. | |
1-Stearo-2-linolein Quick inquiry Where to buy Suppliers range | 1-Stearo-2-linolein is used in the study of the influence of platelet-derived growth factor (PDGF) on diacylglycerol phosphorylation in Swiss 3T3 cells. It is also a possible protein kinase C activator. Group: Biochemicals. Grades: Highly Purified. CAS No. 27095-10-9. Pack Sizes: 10mg, 100mg. Molecular Formula: C39H72O5, Molecular Weight: 620.99. US Biological Life Sciences. | Worldwide |
1-Stearo-2-linolein-d5 Quick inquiry Where to buy Suppliers range | 1-Stearo-2-linolein-d5 is labelled 1-Stearo-2-linolein (S686465) which is used in the study of the influence of platelet-derived growth factor (PDGF) on diacylglycerol phosphorylation in Swiss 3T3 cells. It is also a possible protein kinase C activator. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C39H67D5O5, Molecular Weight: 626.02. US Biological Life Sciences. | Worldwide |
1-Stearo-3-linolein Quick inquiry Where to buy Suppliers range | 1-Stearo-3-linolein is a diacylglycerol from soybean oil deodoriser distillate. Group: Biochemicals. Grades: Highly Purified. CAS No. 126301-96-0. Pack Sizes: 10mg, 100mg. Molecular Formula: C39H72O5, Molecular Weight: 620.99. US Biological Life Sciences. | Worldwide |
1-Stearo-3-linolein-d5 Quick inquiry Where to buy Suppliers range | 1-Stearo-3-linolein-d5 is labelled 1-Stearo-3-linolein (S686455) which is a diacylglycerol from soybean oil deodoriser distillate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C39H67D5O5, Molecular Weight: 626.02. US Biological Life Sciences. | Worldwide |
1-Stearoyl-2-linoleoyl-sn-glycerol Quick inquiry Where to buy Suppliers range | 1-Stearoyl-2-linoleoyl-sn-glycerol is used in the study of the influence of platelet-derived growth factor (PDGF) on diacylglycerol phosphorylation in Swiss 3T3 cells. It is also a possible protein kinase C activator. Group: Biochemicals. Grades: Highly Purified. CAS No. 34487-26-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C39H72O5, Molecular Weight: 620.99. US Biological Life Sciences. | Worldwide |
1-tert-Butyl 3-Methyl 5-Hydroxypiperidine-1,3-dicarboxylate Quick inquiry Where to buy Suppliers range | 1-tert-Butyl 3-Methyl 5-Hydroxypiperidine-1,3-dicarboxylate is an intermediate used in the synthesis of heterocyclyl aminopyrazine derivatives for use as CHK-1 inhibitors. It is also used to prepare pyrrolidinyl imidazopyridinyl piperidinyl methanone derivatives and analogs for use as diacylglycerol acyltransferase 2 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1095010-47-1. Pack Sizes: 50mg, 250mg. Molecular Formula: C12H21NO5, Molecular Weight: 259.3. US Biological Life Sciences. | Worldwide |
2- (2, 3-Diazidopropoxy) tetrahydro-2H-pyran Quick inquiry Where to buy Suppliers range | 2- (2, 3-diazidopropoxy) tetrahydro-2H-pyran is an intermediate in the synthesis of diacylglycerol analogs as potential second-messenger antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 52438-81-0. Pack Sizes: 25mg, 100mg. Molecular Formula: C8H14N6O2. US Biological Life Sciences. | Worldwide |
2- (2, 3-Dibromopropoxy) tetrahydro-2H-pyran Quick inquiry Where to buy Suppliers range | 2- (2, 3-Dibromopropoxy) tetrahydro-2H-pyran is an intermediate in the synthesis of diacylglycerol analogs as potential second-messenger antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 52393-58-5. Pack Sizes: 25mg, 100mg. Molecular Formula: C8H14Br2O2. US Biological Life Sciences. | Worldwide |
2,3-Diaminopropyl Tetrahydropyranyl Ether Quick inquiry Where to buy Suppliers range | 2,3-Diaminopropyl Tetrahydropyranyl Ether is an intermediate in the synthesis of diacylglycerol analogs as potential second-messenger antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 101857-33-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C8H18N2O2. US Biological Life Sciences. | Worldwide |
2-Bromopropionyl Chloride Quick inquiry Where to buy Suppliers range | 2-Bromopropionyl chloride is a reagent that is used in the preparation of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase 1. Group: Biochemicals. Grades: Highly Purified. CAS No. 7148-74-5. Pack Sizes: 1g, 10g. Molecular Formula: C3H4BrClO, Molecular Weight: 171.42. US Biological Life Sciences. | Worldwide |
4(1H)-Quinazolinone,3-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo- Quick inquiry Where to buy Suppliers range | 4(1H)-Quinazolinone,3-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-. Group: Heterocyclic Organic Compound. Alternative Names: diacylglycerol kinase inhibitor ii, MLS000069510, D5794_SIGMA, STO500, CID657356, HSCI1_000348, R 59949, NCGC00018133-01, SMR000058550, R59949, R-59949, R 59 949, C058544, 120166-69-0, 3-(2-(4-(Bis(4-fluorophenyl)methylene)-1-piperdinyl)ethyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone, 3-[2-[4-(bis(4-Fluorophenyl)methylene)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone, 3-{2-[4-[bis-(4-Fluorophenyl)methylene]-1-piperidinyl]ethyl}-2,3-dihydro-2-thioxo-4(1H)quinazolinone, 4(1H)-Quinazolinone, 3-(2-(4-(bis(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-2,3-dihydro-2-thioxo-. Grades: >98%. CAS No. 120166-69-0. Molecular formula: C28H25F2N3OS. Mole weight: 489.58. IUPAC Name: 3-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one. Exact Mass: 489.16900. Boiling Point: 637.1ºC at 760mmHg. Flash Point: 339.1ºC. Density: 1.36g/cm3. SMILES: C1CN (CCC1=C (C2=CC=C (C=C2)F)C3=CC=C (C=C3)F)CCN4C (=O)C5=CC=CC=C5NC4=S. InChIKey: ZCNBZFRECRPCKU-UHFFFAOYSA-N. H-Bond Donor: 1. H-Bond Acceptor: 4. Safty Description: S26-S36. Hazard statements: Xi. | |
ABT-046 Quick inquiry Where to buy Suppliers range | ABT-046 is a potent, selective, and orally bioavailable Diacylglycerol acyltransferase 1 (DGAT-1 ) inhibitor (IC50=8 nM). Synonyms: ABT-046; ABT 046; ABT046. Grades: >98%. CAS No. 1031336-60-3. Molecular formula: C20H22N4O2. Mole weight: 350.41. | |
AZD 3988 Quick inquiry Where to buy Suppliers range | AZD 3988 is a selective and potent diacylglycerol O-acyltransferase (DGAT) enzyme inhibitor with IC50 value of 0.6 nM. It is selective for DGAT-1 over DGAT-2, cytochrome P450 enzymes and Kv11.1 (hERG). It suppresses adipose tissue TAG synthesis and triacylglyceride (TAG) plasma excursion in rats. It reduces body weight of diet-induced obese rats and may be used as a potential treatment for diabetes and other metabolic diseases. It is orally bioavailable and cell permeable. Synonyms: AZD 3988; AZD-3988; AZD3988; trans-4- [- [ [ [5- [ (3, 4-Difluorophenyl) amino] -1, 3, 4-oxadiazol-2-yl] carbonyl] amino] phenyl] cyclohexaneacetic acid. Grades: ≥98% by HPLC. CAS No. 892489-52-0. Molecular formula: C23H22F2N4O4. Mole weight: 456.44. | |
Cochlioquinone A (Luteoleersin) Quick inquiry Where to buy Suppliers range | Cochlioquinone A is the major component of a bioactive pigment isolated from Bipolaris leersia. Cochlioquinone A has been recently shown to be an antagonist of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1). It is anti-angiogenic and exhibits inhibitory activity against diacylglycerol acyltransferase and NADH-ubiquinone reductase. Group: Biochemicals. Alternative Names: Luteoleersin. Grades: Highly Purified. CAS No. 32450-25-2. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
Cochlioquinone B Quick inquiry Where to buy Suppliers range | It is the minor component of a bioactive pigment isolated from Bipolaris cynodontis and Cochliobolus miyabeanus. It is an NADH-ubiquinone reductase inhibitor. It is also a phytotoxic agent inhibiting root growth. It is closely related to cochlioquinone A which inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. It is an antagonist of the human chemokine receptor, CCR5, in HIV-1. Synonyms: 20-De(acetyloxy)-11-deoxy-20-oxo-cochlioquinone A; 9-(1, 3-Dimethyl-2-oxopentyl)-1, 2, 3, 4aα, 5, 6, 6a, 12, 12aα, 12b-decahydro-3β-(1-hydroxy-1-methylethyl)-6aβ, 12bβ-dimethyl-pyrano[3, 2-a]xanthene-8, 11-dione Stereoisomer; (3R,4aR,6aR,12aR,12bR)-9-[(1S,3S)-1,3-Dimethyl-2-oxopentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethylpyrano[3,2-a]xanthene-8,11-dione. Grades: >99% by HPLC. CAS No. 32450-26-3. Molecular formula: C28H40O6. Mole weight: 472.61. | |
Cochlioquinone B Quick inquiry Where to buy Suppliers range | Cochlioquinone B, the minor component of a bioactive pigment isolated from Bipolaris leersia, is an NADH-ubiquinone reductase inhibitor and a phytotoxic agent inhibiting root growth. It is closely related to Cochlioquinone A that inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. Cochlioquinones have been recently shown to be antagonists of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1). Group: Biochemicals. Grades: Highly Purified. CAS No. 32450-26-3. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
DGAT1-IN-1 Quick inquiry Where to buy Suppliers range | Imidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparation. Synonyms: DGAT1-IN-1; DGAT1 IN 1. Grades: >98%. CAS No. 1449779-49-0. Molecular formula: C30H28F3N3O4. Mole weight: 551.56. | |
Dimyristin Quick inquiry Where to buy Suppliers range | Dimyristin is a diacylglycerol. Synonyms: 3-hydroxypropane-1,2-diyl ditetradecanoate; 1,2-Dimyristoyl-rac-glycerol; 1,2-Dimyristin; Glycerol dimyristate; D-alpha,beta-Dimyristin. Grades: >95% by HPLC. CAS No. 53563-63-6. Molecular formula: C31H60O5. Mole weight: 512.80. | |
Dioctanoylglycol Quick inquiry Where to buy Suppliers range | Dioctanoylglycol has been found to be a diacylglycerol kinase (DGK) inhibitor. Synonyms: Dioctanoyl ethylene glycol; 2-Octanoyloxyethyl octanoate. Grades: ≥95% by HPLC. CAS No. 627-86-1. Molecular formula: C18H34O4. Mole weight: 314.46. | |
Ethyl Isobutyrylacetate Quick inquiry Where to buy Suppliers range | Ethyl Isobutyrylacetate is used in the synthesis of piperazine derivatives as possible multireceptor atypical antipsychotics, affecting dopamine and serotonin receptor properties. Also used in the synthesis of pyrazinecarboxamide DGAT1 (diacylglycerol acyltransferase 1) inhibitors used in the treatment of obesity. Group: Biochemicals. Alternative Names: 3-Oxo-4-methylpentanoic Acid Ethyl Ester; 4-Methyl-3-oxo-pentanoic Acid Ethyl Ester; 4-Methyl-3-oxovaleric Acid Ethyl Ester; Ethyl 2-isobutyrylacetate; Ethyl 3-Isopropyl-3-oxopropanoate; Ethyl 3-oxo-4-methylpentanoate; Ethyl 3-Oxo-4-methylvalerate; Ethyl 4-Methyl-3-oxopentanoate; Ethyl 4-Methyl-3-oxovalerate; Ethyl Isobutyrylacetate; Isobutyrylacetic Acid Ethyl Ester; NSC 62029; γ,γ-Dimethylacetoacetic Acid Ethyl Ester; Ethyl 4-Methyl-3-oxopentanoate. Grades: Highly Purified. CAS No. 7152-15-0. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
Glycerol-d5 1,3-Dipalmitate Quick inquiry Where to buy Suppliers range | A glycidol fatty acid esters in edible oils. An acyl acceptor for the unspecific bifunctional wax ester synthase/acyl-CoA:Diacylglycerol acyltransferase. Group: Biochemicals. Alternative Names: 1,3-Dipalmitin-d5; 1,3-Dipalmitoylglycerin-d5; 1,3-Dipalmitoylglycerol-d5; Glycerol-d5 1,3-Dihexadecanoate; Hexadecanoic-d5 Acid 2-Hydroxy-1,3-propanediyl Ester. Grades: Highly Purified. CAS No. 65615-82-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Glyceryl Monostearate Quick inquiry Where to buy Suppliers range | While the names glyceryl monostearate and mono- and diglycerides are used for a variety of esters of long-chain fatty acids, the esters fall into two distinct grades: 40-55 percent monoglycerides The PhEur describes glyceryl monostearate 40-55 as a mixture of monoacylglycerols, mostly monostearoylglycerol, together with quantities of di- and triacylglycerols. It contains 40-55% of monoacylglycerols, 30-45% of diacylglycerols, and 5-15% of triacylglycerols. Uses: Used for research and manufacturing. Group: Emulsifier Excipients. Alternative Names: Capmul GMS-50; Cutina GMS; 2, 3-dihydroxypropyl octadecanoate; Geleol; glycerine monostearate; glycerin monostearate; glycerol monostearate; glyceroli monostearas; glycerol stearate; glyceryl stearate; GMS; HallStar GMS; Imwitor 191; Imwitor 900; Kessco GMS; Lipo GMS; monoester with 1, 2, 3-propanetriol; monostearin; Myvaplex 600P; Myvatex; 1, 2, 3-propanetriol octadecanoate; Protachem GMS-450; Rita GMS; stearic acid, monoester with glycerol; stearic monoglyceride; Stepan GMS; Tegin; Tegin 503; Tegin 515; Tegin 4100; Tegin M; Unimate GMS. Grades: Pharmceutical Excipients. CAS No. 31566-31-1. Product ID: PE-0518. | |
Hexadecyl methyl glycerol Quick inquiry Where to buy Suppliers range | Hexadecyl methyl glycerol is a synthetic diacylglycerol with a hexadecyl chain at the sn-1 position and a methyl group at the sn-2 position. It inhibits protein kinase C (PKC) activity in human neutrophils. Synonyms: 1-O-hexadecyl-2-O-methyl-sn-glycerol. Grades: ≥98%. CAS No. 96960-92-8. Molecular formula: C20H42O3. Mole weight: 330.6. | |
JTP 103237 Quick inquiry Where to buy Suppliers range | JTP 103237 is a potent and selective monoacyglycerol acyltransferase 2 (MGAT2) inhibitor (IC50 = 20-40 nM), exhibiting >7000-fold selectivity for human MOGAT2 over human DGAT2. In a high sucrose very low fat (HSVLF) diet induced fatty liver model, JTP-103237 reduced hepatic triglyceride content and hepatic MGAT activity, suppressed not only triglyceride (TG) and diacylglycerol (DG) synthesis, but also fatty acid (FA) synthesis (de novo lipogenesis). Synonyms: 7-[4,6-Bis(1,1-dimethylethyl)-2-pyrimidinyl]-5,6,7,8-tetrahydro-3-[4-(trifluoromethoxy)phenyl]-1,2,4-triazolo[4,3-a]pyrazine. Grades: ≥98% by HPLC. CAS No. 1883864-16-1. Molecular formula: C24H29F3N6O. Mole weight: 474.52. | |
LCQ-908 Quick inquiry Where to buy Suppliers range | LCQ-908 is a new generation of diacylglycerol acyltransferase 1 (DGAT1) inhibitor as anti-obesity and anti-diabetic agents. It is now in phase II clinical trials. Synonyms: Pradigastat; LCQ-908; LCQ 908; LCQ908. Grades: >98%. CAS No. 956136-95-1. Molecular formula: C25H24F3N3O2. Mole weight: 455.47. | |
N-[ (Phenylmethoxy) carbonyl]-L-serine Methyl Ester Quick inquiry Where to buy Suppliers range | N-[ (Phenylmethoxy) carbonyl]-L-serine Methyl Ester is used to inhibit the activity of Mycobacterium tuberculosis in studies. Also used in the synthesis of pyrazinecarboxamide-based compounds acting as inhibitors of diacylglycerol acetyltransferases regarding treatment of obesity. Group: Biochemicals. Alternative Names: N-Benzyl-N-carboxyserine Methyl Ester; N-Benzyl-N-carboxy-L-serine Methyl Ester; (2S) -2-[ (Benzyloxycarbonyl) amino]-3-hydroxypropionic Acid Methyl Ester; (2S) -2-[ (Benzyloxycarbonyl) amino]-3-hydroxypropionic Acid Methyl Ester; (Benzyloxycarbonyl)-L-serine Methyl Ester; Methyl (2S) -2-[ (Benzyloxycarbonyl) amino]-3-hydroxypropanoate; Methyl (S) -2- ( (Benzyloxycarbonyl) amino) -3-hydroxypropanoate; Methyl N-(Benzyloxycarbonyl)-L-serinate; N-(Benzyloxycarbonyl)-L-serine Methyl Ester; N- (Benzyloxycarbonyl) serine Methyl Ester; N-Carbobenzoxy-L-serine Methyl Ester. Grades: Highly Purified. CAS No. 1676-81-9. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
O-7460 Quick inquiry Where to buy Suppliers range | O-7460 is a selective inhibitor of 2-arachidonoyl glycerol (2-AG) biosynthesis via diacylglycerol lipase (DAGL). O-7460 dose-dependently inhibited the intake of a high-fat diet and reduced body weight in mice. Synonyms: [1-[fluoro(methyl)phosphoryl]oxy-3-propan-2-yloxypropan-2-yl] (Z)-octadec-9-enoate. Grades: ≥95%. CAS No. 1572051-31-0. Molecular formula: C25H48FO5P. Mole weight: 478.6. | |
Orlistat Quick inquiry Where to buy Suppliers range | Hypolipemic cell permeable and irreversible pancreatic, gastric and carboxylester lipase inhibitor. Anti-obesity and antihypercholesterolem ic compound. Antitumor compound by inhibition of the thioesterase domain of fatty acid synthase (FASN). Anti-proliferative. Causes cell cycle arrest at G1 phase. Apoptosis inducer through caspase-3 activation. Sn-1-selective-diacylglycerol lipases alpha (DAGLalpha) inhibitor. Targets serine hydrolases in the nervous system, such as diacylglycerol lipase (DAGL), which is responsible for the conversion of DAG to 2-AG. Partially inhibits the hydrolysis of triglycerides and lowers the absorption of dietary fat, promoting weight loss. Promotes the sensitivity to TRAIL in cancer cells by ROS-mediated pathways. Source:Synthetic. Originally isolated from Streptomyces sp. Group: Biochemicals. Grades: Highly Purified. CAS No. 96829-58-2. Pack Sizes: 50mg, 250mg. Molecular Formula: C29H53NO5. US Biological Life Sciences. | Worldwide |
PF 06424439 Quick inquiry Where to buy Suppliers range | PF 06424439 is a potent, selective and orally bioavailable Diacylglycerol Acyltransferase 2 ( DGAT2) inhibitor with DGAT2 IC50 ± SEM (nM) (human/rat/dog) 14 ± 1/38 ± 4/16 ± 1, which exhibits no significant activity at MGAT1-3 or DGAT1. It reduces triglyderide synthesis in human hepatocytes in vitro, and reduces plasma triglyceride and cholesterol levels in a rat dyslipidemia model. Synonyms: [(3R)-1-[2-[1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl]-3H-imidazo[4,5-b]pyridin-5-yl]-3-piperidinyl]-1-pyrrolidinylmethanone methanesulfonate; PF-06424439; PF06424439; PF 06424439; PF-6424439; PF-6424439; PF 6424439. Grades: ≥98% by HPLC. CAS No. 1469284-79-4. Molecular formula: C22H26ClN7O.CH4O3S. Mole weight: 536.05. | |
POPC Quick inquiry Where to buy Suppliers range | POPC is phosphatidylcholine, a diacylglycerol and phospholipid. Its full name is 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine. BOC Sciences provides high-quality POPC for your projects. Uses: Giant popc liposomes have been used to study the effect of non-ionic detergent on liposomes. Synonyms: 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC; 1,2-POPC; POPC (16:0/18:1 PC). Grades: ≥ 98%. CAS No. 26853-31-6. Molecular formula: C42H82NO8P. Mole weight: 760.08. | |
Putative protein product of HMFN1045 (253-264) Quick inquiry Where to buy Suppliers range | Diacylglycerol O-acyltransferase 2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-139. | |
R 59-022 Quick inquiry Where to buy Suppliers range | R 59-022 is a diacylglycerol (DAG) kinase inhibitor (IC50 = 2.8 μM) without affecting phosphodiesterase or phosphatidylinositol kinase, and potentiates the activity of protein kinase C by inhibiting diacylglycerol metabolism. R 59-022 also blocks vascular contraction induced by the thromboxane analog U-46619. At 10 μM, R 59-022 induces apoptosis in glioblastoma cells without being toxic to non-cancerous cells. Uses: Enzyme inhibitors. Synonyms: R59022; R-59022; R 59022; 6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one; Diacylglycerol Kinase Inhibitor I. Grades: ≥98% by HPLC. CAS No. 93076-89-2. Molecular formula: C27H26FN3OS. Mole weight: 459.58. | |
R-59-949 Quick inquiry Where to buy Suppliers range | R-59-949 is an inhibitor of diacylglycerol kinase α (DGK-α) expressed in vascular smooth muscle cells. It inhibits inducible nitric oxide production in vascular smooth muscle cells through decreasing transplasmalemmal L-arginine uptake. Synonyms: Diacylglycerol Kinase Inhibitor II; DKGI-II; R 59949; R 59 949. Grades: ≥98%. CAS No. 120166-69-0. Molecular formula: C28H25F2N3OS. Mole weight: 489.6. | |
(R)-KT109 Quick inquiry Where to buy Suppliers range | (R)-KT109 is the R isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109. Synonyms: (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[(2R)-2-(phenylmethyl)-1-piperidinyl]-methanone. Grades: ≥98%. CAS No. 2055172-60-4. Molecular formula: C27H26N4O. Mole weight: 422.52. | |
RO31-8220 Quick inquiry Where to buy Suppliers range | Ro 31-8220 is a PKC-inhibitor, which inhibits stimulated fluid pinocytosis of human PMNs induced by the PKC-activators phorbol myristate acetate or diacylglycerols by 95%. Ro-31-8220 showed the apoptotic effect on HL-60 cells, which was mediated by a well-characterized transduction process of apoptotic signals. Moreover, the ability of Ro-31-8220 to induce apoptotic activation was completely inhibited by the over-expression of the apoptotic suppressor gene, Bcl-2, in the cells. Uses: Enzyme inhibitors. Synonyms: RO31-8220; RO 31-8220; RO-31-8220; RO318220. Grades: 0.98. CAS No. 125314-64-9. Molecular formula: C25H23N5O2S. Mole weight: 457.552. | |
(S)-KT109 Quick inquiry Where to buy Suppliers range | (S)-KT109 is the S isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109. Synonyms: (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[(2S)-2-(phenylmethyl)-1-piperidinyl]-methanone; [(2S)-2-benzylpiperidin-1-yl]-[4-(4-phenylphenyl)triazol-1-yl]methanone. Grades: ≥98%. CAS No. 2055172-61-5. Molecular formula: C27H26N4O. Mole weight: 422.52. | |
T863 Quick inquiry Where to buy Suppliers range | T-863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. It causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice. Synonyms: DGAT-1 inhibitor; DGAT 1 inhibitor; T863; T-863; T 863. Grades: >98%. CAS No. 701232-20-4. Molecular formula: C22H26N4O3. Mole weight: 394.47. | |
URB602 Quick inquiry Where to buy Suppliers range | URB602, a cell-permeable N-biphenyl carbamate compound, is a selective inhibitor of monoglycerol lipase (MGL). The IC50 = 28 μM and Km = 20 μM. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 μM or other lipid metabolizing enzymes such as diacylglycerol lipase or COX-2. Synonyms: cyclohexyl [1,1'-biphenyl]-3-ylcarbamate; URB602; URB-602; URB 602. CAS No. 565460-15-3. Molecular formula: C19H21NO2. Mole weight: 295.38. |