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1-Alkyl-2-acylglycerol can act as acceptor; this activity was previously listed separately. Group: Enzymes. Synonyms: phosphorylcholine-glyceride transferase; alkylacylglycerol cholinephosphotransferase; 1-alkyl-2-acetylglycerol cholinephosphotransferase; cholinephosphotransferase; CPT; alkylacylglycerol choline phosphotransferase; diacylgl. Enzyme Commission Number: EC 2.7.8.2. CAS No. 9026-13-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3319; diacylglycerol cholinephosphotransferase; EC 2.7.8.2; 9026-13-5; phosphorylcholine-glyceride transferase; alkylacylglycerol cholinephosphotransferase; 1-alkyl-2-acetylglycerol cholinephosphotransferase; cholinephosphotransferase; CPT; alkylacylglycerol choline phosphotransferase; diacylglycerol choline phosphotransferase; 1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase; CDP-choline diglyceride phosphotransferase; cytidine diphosphocholine glyceride transferase; cytidine diphosphorylcholine diglyceride transferase; phosphocholine diacylglyceroltransferase; sn-1,2-diacylglycerol cholinephosphotransferase; 1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase; CDP choline:1,2-diacylglycerol cholinephosphotransferase; CDP-choline:1,2-diacylglycerol cholinephosphotransferase. Cat No: EXWM-3319.
diacylglycerol diphosphate phosphatase
The bifunctional enzyme catalyses the dephosphorylation of diacylglycerol diphosphate to phosphatidate and the subsequent dephosphorylation of phosphatidate to diacylglycerol (cf. phosphatidate phosphatase (EC 3.1.3.4)). It regulates intracellular levels of diacylglycerol diphosphate and phosphatidate, phospholipid molecules believed to play a signalling role in stress response. The phosphatase activity of the bifunctional enzyme is Mg2+-independent and N-ethylmaleimide-insensitive and is distinct from the Mg2+-dependent and N-ethylmaleimide-sensitive enzyme EC 3.1.3.4 (phosphatidate phosphatase).The diacylglycerol pyrophosphate phosphatase activity in Saccharomyces cerevisiae is induced by zinc depletion, by inositol supplementation, and when cells enter the stationary phase. Group: Enzymes. Synonyms: DGPP phosphatase; DGPP phosphohydrolase; DPP1; DPPL1; DPPL2; PAP2; pyrophosphate phosphatase. Enzyme Commission Number: EC 3.1.3.81. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3687; diacylglycerol diphosphate phosphatase; EC 3.1.3.81; DGPP phosphatase; DGPP phosphohydrolase; DPP1; DPPL1; DPPL2; PAP2; pyrophosphate phosphatase. Cat No: EXWM-3687.
diacylglycerol kinase (ATP)
Involved in synthesis of membrane phospholipids and the neutral lipid triacylglycerol. Activity is stimulated by certain phospholipids. In plants and animals the product 1,2-diacyl-sn-glycerol 3-phosphate is an important second messenger. cf. EC 2.7.1.174, diacylglycerol kinase (CTP). Group: Enzymes. Synonyms: diglyceride kinase (ambiguous); 1,2-diacylglycerol kinase (phosphorylating) (ambiguous); 1,2-diacylglycerol kinase (ambiguous); sn-1,2-diacylglycerol kinase (ambiguous); DG kinase (ambiguous); DGK (ambiguous); ATP:diacylglycerol phosphotransferase; arachidonoyl-specific diacylglycerol kinase; diacylglycerol:ATP kinase; ATP:1,2-diacylglycerol 3-phosphotransferase; diacylgly. Enzyme Commission Number: EC 2.7.1.107. CAS No. 60382-71-0. DAGK. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2953; diacylglycerol kinase (ATP); EC 2.7.1.107; 60382-71-0; diglyceride kinase (ambiguous); 1,2-diacylglycerol kinase (phosphorylating) (ambiguous); 1,2-diacylglycerol kinase (ambiguous); sn-1,2-diacylglycerol kinase (ambiguous); DG kinase (ambiguous); DGK (ambiguous); ATP:diacylglycerol phosphotransferase; arachidonoyl-specific diacylglycerol kinase; diacylglycerol:ATP kinase; ATP:1,2-diacylglycerol 3-phosphotransferase; diacylglycerol kinase (ATP dependent). Cat No: EXWM-2953.
diacylglycerol kinase (CTP)
Requires Ca2+ or Mg2+ for activity. Involved in synthesis of membrane phospholipids and the neutral lipid triacylglycerol. Unlike the diacylglycerol kinases from bacteria, plants, and animals [cf. EC 2.7.1.107, diacylglycerol kinase (ATP)], the enzyme from Saccharomyces cerevisiae utilizes CTP. The enzyme can also use dCTP, but not ATP, GTP or UTP. Group: Enzymes. Synonyms: DAG kinase; CTP-dependent diacylglycerol kinase; diglyceride kinase (ambiguous); DGK1 (gene name); diacylglycerol kinase (CTP dependent). Enzyme Commission Number: EC 2.7.1.174. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3005; diacylglycerol kinase (CTP); EC 2.7.1.174; DAG kinase; CTP-dependent diacylglycerol kinase; diglyceride kinase (ambiguous); DGK1 (gene name); diacylglycerol kinase (CTP dependent). Cat No: EXWM-3005.
diacylglycerol O-acyltransferase
Palmitoyl-CoA and other long-chain acyl-CoAs can act as donors. Group: Enzymes. Synonyms: diglyceride acyltransferase; 1,2-diacylglycerol acyltransferase; diacylglycerol acyltransferase; diglyceride O-acyltransferase; palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase; acyl-CoA:1,2-diacylglycerol O-acyltransferase. Enzyme Commission Number: EC 2.3.1.20. CAS No. 9029-98-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2144; diacylglycerol O-acyltransferase; EC 2.3.1.20; 9029-98-5; diglyceride acyltransferase; 1,2-diacylglycerol acyltransferase; diacylglycerol acyltransferase; diglyceride O-acyltransferase; palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase; acyl-CoA:1,2-diacylglycerol O-acyltransferase. Cat No: EXWM-2144.
diacylglycerol-sterol O-acyltransferase
Cholesterol, sitosterol, campesterol and diacylglycerol can act as acceptors. Transfers a number of long-chain fatty acyl groups. Group: Enzymes. Synonyms: 1,2-diacyl-sn-glycerol:sterol acyl transferase. Enzyme Commission Number: EC 2.3.1.73. CAS No. 79586-23-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2253; diacylglycerol-sterol O-acyltransferase; EC 2.3.1.73; 79586-23-5; 1,2-diacyl-sn-glycerol:sterol acyl transferase. Cat No: EXWM-2253.
1,2-diacylglycerol 3-α-glucosyltransferase
The enzyme from the bacterium Acholeplasma laidlawii, which lacks a cell wall, produces the major non-bilayer lipid in the organism. The enzyme from the bacterium Agrobacterium tumefaciens acts under phosphate deprivation, generating glycolipids as surrogates for phospholipids. The enzyme belongs to the GT4 family of configuration-retaining glycosyltransferases. Many diacylglycerols with long-chain acyl groups can act as acceptors. cf. EC 2.4.1.336, monoglucosyldiacylglycerol synthase. Group: Enzymes. Synonyms: mgs (gene name); UDP-glucose:diacylglycerol glucosyltransferase; UDP-glucose:1,2-diacylglycerol glucosyltransferase; uridine diphosphoglucose-diacylglycerol glucosyltransferas. Enzyme Commission Number: EC 2.4.1.337. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2575; 1,2-diacylglycerol 3-α-glucosyltransferase; EC 2.4.1.337; mgs (gene name); UDP-glucose:diacylglycerol glucosyltransferase; UDP-glucose:1,2-diacylglycerol glucosyltransferase; uridine diphosphoglucose-diacylglycerol glucosyltransferase; UDP-glucose-diacylglycerol glucosyltransferase; UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase; UDP-glucose:1,2-diacyl-sn-glycerol 3-D-glucosyltransferase; 1,2-diacylglycerol 3-glucosyltransferase (ambiguous). Cat No: EXWM-2575.
CDP-diacylglycerol diphosphatase
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is CDP-diacylglycerol phosphatidylhydrolase. Other names in common use include cytidine diphosphodiacylglycerol pyrophosphatase, and CDP diacylglycerol hydrolase. This enzyme participates in glycerophospholipid metabolism. Group: Enzymes. Synonyms: cytidine diphosphodiacylglycerol pyrophosphatase; CDP diacylglycerol hydrolase. Enzyme Commission Number: EC 3.6.1.26. CAS No. 62213-20-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4610; CDP-diacylglycerol diphosphatase; EC 3.6.1.26; 62213-20-1; cytidine diphosphodiacylglycerol pyrophosphatase; CDP diacylglycerol hydrolase. Cat No: EXWM-4610.
The enzyme catalyses the committed step in the biosynthesis of acidic phospholipids known by the common names phophatidylglycerols and cardiolipins. Group: Enzymes. Synonyms: glycerophosphate phosphatidyltransferase; 3-phosphatidyl-1'-glycerol-3'-phosphate synthase; CDP. Enzyme Commission Number: EC 2.7.8.5. CAS No. 9068-49-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3343; CDP-diacylglycerol-glycerol-3-phosphate 1-phosphatidyltransferase; EC 2.7.8.5; 9068-49-9; glycerophosphate phosphatidyltransferase; 3-phosphatidyl-1'-glycerol-3'-phosphate synthase; CDPdiacylglycerol:glycerol-3-phosphate phosphatidyltransferase; cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDP-diglyceride):sn-glycerol-3-phosphate phosphatidyltransferase; phosphatidylglycerophosphate synthase; phosphatidylglycerolphosphate synthase; PGP synthase; CDP-diacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase; CDP-diacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase; glycerol phosphate phosphatidyltransferase; glycerol 3-phosphate phosphatidyltransferase; phosphatidylglycerol phosphate synthase; phosphatidylglycerol phosphate synthetase; phosphatidylglycerophosphate synthetase; sn-glycerol-3-phosphate phosphatidyltransferase. Cat No: EXWM-3
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. This enzyme participates in glycerophospholipid metabolism and phosphatidylinositol signaling system. Group: Enzymes. Synonyms: CDP-diglyceride-inositol phosphatidyltransferase; phosphatidylinositol synthase; CDP-diacylglycerol-inositol phosphatidyltransferase; CDP-diglyceride:inositol transferase; cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol 3-phosph. Enzyme Commission Number: EC 2.7.8.11. CAS No. 9027-1-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3311; CDP-diacylglycerol-inositol 3-phosphatidyltransferase; EC 2.7.8.11; 9027-01-4; CDP-diglyceride-inositol phosphatidyltransferase; phosphatidylinositol synthase; CDP-diacylglycerol-inositol phosphatidyltransferase; CDP-diglyceride:inositol transferase; cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol 3-phosphatidyltransferase; CDP-DG:inositol transferase; cytidine diphosphodiglyceride-inositol phosphatidyltransferase; CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase; CDP-diglyceride-inositol transferase; cytidine diphosphoglyceride-inositol phosphatidyltransferase; cytidine diphosphoglyceride-inositol transferase. Cat No: EXWM-3311.
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. This enzyme participates in glycine, serine and threonine metabolism and glycerophospholipid metabolism. Group: Enzymes. Synonyms: phosphatidylserine synthase; CDPdiglyceride-serine O-phosphatidyltransferase; PS synthase; cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase; phosphatidylserine synthetase; CDP-di. Enzyme Commission Number: EC 2.7.8.8. CAS No. 9068-48-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3346; CDP-diacylglycerol-serine O-phosphatidyltransferase; EC 2.7.8.8; 9068-48-8; phosphatidylserine synthase; CDPdiglyceride-serine O-phosphatidyltransferase; PS synthase; cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase; phosphatidylserine synthetase; CDP-diacylglycerol-L-serine O-phosphatidyltransferase; cytidine diphosphoglyceride-serine O-phosphatidyltransferase; CDP-diglyceride-L-serine phosphatidyltransferase; CDP-diglyceride:serine phosphatidyltransferase; cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase; CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase. Cat No: EXWM-3346.
digalactosyldiacylglycerol synthase
Requires Mg2+. Diacylglycerol cannot serve as an acceptor molecule for galactosylation as in the reaction catalysed by EC 2.4.1.46, monogalactosyldiacylglyerol synthase. When phosphate is limiting, phospholipids in plant membranes are reduced but these are replaced, at least in part, by the glycolipids digalactosyldiacylglycerol (DGDG) and sulfoquinovosyldiacylglycerol. While both DGD1 and DGD2 are increased under phosphate-limiting conditions, DGD2 does not contribute significantly under optimal growth conditions. DGD2 is responsible for the synthesis of DGDG molecular species that are rich in C16 fatty acids at sn-1 of diacylglycerol whereas DGD1 leads to molecular specie...tose:MGDG galactosyltransferase; UDP-galactose:3-(β-D-galactosyl)-1,2-diacyl-sn-glycerol 6-α-galactosyltransferase. Enzyme Commission Number: EC 2.4.1.241. CAS No. 69913-00-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2470; digalactosyldiacylglycerol synthase; EC 2.4.1.241; 69913-00-4; DGD1; DGD2; DGDG synthase (ambiguous); UDP-galactose-dependent DGDG synthase; UDP-galactose-dependent digalactosyldiacylglycerol synthase; UDP-galactose:MGDG galactosyltransferase; UDP-galactose:3-(β-D-galactosyl)-1,2-diacyl-sn-glycerol 6-α-galactosyltransferase. Cat No: EXWM-2470.
diglucosyl diacylglycerol synthase (1,2-linking)
The enzyme from Acholeplasma laidlawii requires Mg2+. Group: Enzymes. Synonyms: monoglucosyl diacylglycerol (1?2) glucosyltransferase; MGlcDAG (1?2) glucosyltransferase; DGlcDAG synthase (ambiguous); UDP-glucose:1,2-diacyl-3-O-(α-D-glucopyranosyl)-sn-glycerol (1?2) glucosyltransferase; diglucosyl diacylglycerol synthase. Enzyme Commission Number: EC 2.4.1.208. CAS No. 168680-19-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2435; diglucosyl diacylglycerol synthase (1,2-linking); EC 2.4.1.208; 168680-19-1; monoglucosyl diacylglycerol (1?2) glucosyltransferase; MGlcDAG (1?2) glucosyltransferase; DGlcDAG synthase (ambiguous); UDP-glucose:1,2-diacyl-3-O-(α-D-glucopyranosyl)-sn-glycerol (1?2) glucosyltransferase; diglucosyl diacylglycerol synthase. Cat No: EXWM-2435.
diglucosyl diacylglycerol synthase (1,6-linking)
The enzyme is found in several bacterial species. The enzyme from Bacillus subtilis is specific for glucose. The enzyme from Mycoplasma genitalium can incoporate galactose with similar efficiency, but forms mainly 1,2-diacyl-diglucopyranosyl-sn-glycerol in vivo. The enzyme from Staphylococcus aureus can also form glucosyl-glycero-3-phospho-(1'-sn-glycerol). Group: Enzymes. Synonyms: monoglucosyl diacylglycerol (1?6) glucosyltransferase; MGlcDAG (1?6) glucosyltransferase; DGlcDAG synthase (ambiguous); UGT106B1; ypfP (gene name). Enzyme Commission Number: EC 2.4.1.315. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2551; diglucosyl diacylglycerol synthase (1,6-linking); EC 2.4.1.315; monoglucosyl diacylglycerol (1?6) glucosyltransferase; MGlcDAG (1?6) glucosyltransferase; DGlcDAG synthase (ambiguous); UGT106B1; ypfP (gene name). Cat No: EXWM-2551.
glycosylphosphatidylinositol diacylglycerol-lyase
This enzyme is also active when O-4 of the glucosamine is substituted by carrying the oligosaccharide that can link a protein to the structure. It therefore cleaves proteins from the lipid part of the glycosylphostphatidylinositol (GPI) anchors. In some cases, the long-chain acyl group at the sn-1 position of glycerol is replaced by an alkyl or alk-1-enyl group. In other cases, the diacylglycerol is replaced by ceramide (see Lip-1.4 and Lip-1.5 for definition). The only characterized enzyme with this specificity is from Trypanosoma brucei, where the acyl groups are myristoyl, but the function of the trypanosome enzyme is unknown. Substitution on O-2 of the inositol b...No. 129070-68-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5351; glycosylphosphatidylinositol diacylglycerol-lyase; EC 4.6.1.14; 129070-68-4; (glycosyl)phosphatidylinositol-specific phospholipase C; GPI-PLC; GPI-specific phospholipase C; VSG-lipase; glycosyl inositol phospholipid anchor-hydrolyzing enzyme; glycosylphosphatidylinositol-phospholipase C; glycosylphosphatidylinositol-specific phospholipase C; variant-surface-glycoprotein phospholipase C; 6-(α-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming). Cat No: EXWM-5351.
monogalactosyldiacylglycerol synthase
This enzyme adds only one galactosyl group to the diacylglycerol; EC 2.4.1.241, digalactosyldiacylglycerol synthase, adds a galactosyl group to the product of the above reaction. There are three isoforms in Arabidopsis that can be divided into two types, A-type (MGD1) and B-type (MGD2 and MGD3). MGD1 is the isoform responsible for the bulk of monogalactosyldiacylglycerol (MGDG) synthesis in Arabidopsis. Group: Enzymes. Synonyms: uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase; UDP-galactose:diacylglycerol galactosyltransferase; MGDG synthase; UDP galactose-1,2-diacylglycerol galactosyltransferase; UDP-gal. Enzyme Commission Number: EC 2.4.1.46. CAS No. 37277-55-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2592; monogalactosyldiacylglycerol synthase; EC 2.4.1.46; 37277-55-7; uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase; UDP-galactose:diacylglycerol galactosyltransferase; MGDG synthase; UDP galactose-1,2-diacylglycerol galactosyltransferase; UDP-galactose-diacylglyceride galactosyltransferase; UDP-galactose:1,2-diacylglycerol 3-β-D-galactosyltransferase; 1β-MGDG; 1,2-diacylglycerol 3-β-galactosyltransferase; UDP-galactose:1,2-diacyl-sn-glycerol 3-β-D-galactosyltransferase. Cat No: EXWM-2592.
monoglucosyldiacylglycerol synthase
The enzymes from cyanobacteria are involved in the biosynthesis of galactolipids found in their photosynthetic membranes. The enzyme belongs to the GT2 family of configuration-inverting glycosyltranferases. cf. EC 2.4.1.337, 1,2-diacylglycerol 3-α-glucosyltransferase. Group: Enzymes. Synonyms: mgdA (gene name). Enzyme Commission Number: EC 2.4.1.336. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2574; monoglucosyldiacylglycerol synthase; EC 2.4.1.336; mgdA (gene name). Cat No: EXWM-2574.
Native Escherichia coli Diacylglycerol Kinase
Diacylglycerol kinase (DGK or DAGK) is a family of enzymes that catalyzes the conversion of diacylglycerol (DAG) to phosphatidic acid (PA) utilizing ATP as a source of the phosphate. In non-stimulated cells, DGK activity is low allowing DAG to be used for glycerophospholipid biosynthesis but on receptor activation of the phosphoinositide pathway, DGK activity increases driving the conversion of DAG to PA. As both lipids are thought to function as bioactive lipid signaling molecules with distinct cellular targets, DGK therefore occupies an important position, effectively serving as a switch by terminating the signalling of one lipid while simultaneously activating signa...n of dgka and plsb genes of phospholipid synthesis by multiple stress responses in escherichia coli. diacylglycerol kinase from escherichia coli has also been used in a study to identify an alcohol binding site in the first cysteine-rich domain of protein kinase cdelta. Group: Enzymes. Synonyms: Diacylglycerol Kinase; DGK; DAGK; EC 2.7.1.107; Diacylglycerol kinase (ATP); sn-1,2-Diacylglycerol kinase. Enzyme Commission Number: EC 2.7.1.107. CAS No. 60382-71-0. DAGK. Mole weight: mol wt 13.7 kDa. Stability: -70°C. Form: suspension. Source: E. coli. Diacylglycerol Kinase; DGK; DAGK; EC 2.7.1.107; Diacylglycerol kinase (ATP); sn-1,2-Diacylglycerol kinase. Cat No: NATE-0181.
phosphatidylinositol diacylglycerol-lyase
This enzyme is bacterial. Activity is also found in animals, but this activity is due to the presence of EC 3.1.4.11, phosphoinositide phospholipase C. Group: Enzymes. Synonyms: monophosphatidylinositol phosphodiesterase; phosphatidylinositol phospholipase C; 1-phosphatidylinositol phosphodiesterase; 1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming); 1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming). Enzyme Commission Number: EC 4.6.1.13. CAS No. 37288-19-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5350; phosphatidylinositol diacylglycerol-lyase; EC 4.6.1.13; 37288-19-0; monophosphatidylinositol phosphodiesterase; phosphatidylinositol phospholipase C; 1-phosphatidylinositol phosphodiesterase; 1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming); 1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming). Cat No: EXWM-5350.
phospholipid:diacylglycerol acyltransferase
This enzyme differs from EC 2.3.1.20, diacylglycerol O-acyltransferase, by synthesising triacylglycerol using an acyl-CoA-independent mechanism. The specificity of the enzyme for the acyl group in the phospholipid varies with species, e.g., the enzyme from castor bean (Ricinus communis) preferentially incorporates vernoloyl (12,13-epoxyoctadec-9-enoyl) groups into triacylglycerol, whereas that from the hawk's beard (Crepis palaestina) incorporates both ricinoleoyl (12-hydroxyoctadec-9-enoyl) and vernoloyl groups. The enzyme from the yeast Saccharomyces cerevisiae specifically transfers acyl groups from the sn-2 position of the phospholipid to diacylglycerol, thus forming an sn-1-lysophospholipid. Group: Enzymes. Synonyms: PDAT. Enzyme Commission Number: EC 2.3.1.158. CAS No. 288587-47-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2097; phospholipid:diacylglycerol acyltransferase; EC 2.3.1.158; 288587-47-3; PDAT. Cat No: EXWM-2097.
1,2-Dilaurin
1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981). Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (Rac)-1,2-Didodecanoylglycerol. CAS No. 17598-94-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W127391.
1,2-Dilauroyl-sn-glycerol
1,2-Dilauroyl-sn-glycerol is a saturated diacylglycerol (DAG) with lauric acid. DAGs are commonly used as emulsifiers in pharmaceutical manufacturing and food industry. DAGs act as second messenger signaling lipid and activate PKC. Synonyms: Dodecanoic acid, 1,1'-[(1S)-1-(hydroxymethyl)-1,2-ethanediyl] ester; Dodecanoic acid, (1S)-1-(hydroxymethyl)-1,2-ethanediyl ester; Dodecanoic acid, 1-(hydroxymethyl)-1,2-ethanediyl ester, (S)-; sn-1,2-Dilauroylglycerol; (S)-3-hydroxypropane-1,2-diyl didodecanoate. Grades: >99%. CAS No. 60562-15-4. Molecular formula: C27H52O5. Mole weight: 456.70.
1,2-Dilinoleoylglycerol-d5
1,2-Dilinoleoylglycerol-d5 is labelled 1,2-Dilinoleoylglycerol (D460605) which is a diacylglycerol from palm oil deodorizer distillate. It can be used as an Immunostimulant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C39H63D5O5, Molecular Weight: 621.99. US Biological Life Sciences.
Worldwide
1,2-Dilinoleoyl-sn-glycerol
1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (HY-N0729) (18:2) side chains attached at both the sn-1 and sn-2 positions. It has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes. 1,2-Dilinoleoyl-sn-glycerol is upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy. Uses: Scientific research. Group: Signaling pathways. CAS No. 24529-89-3. Pack Sizes: 5 mg (16.21 mM * 500 μL in Acetonitrile); 10 mg (16.21 mM * 1 mL in Acetonitrile). Product ID: HY-117168.
1,2-Dimyristoyl-sn-glycerol
1,2-Dimyristoyl-sn-glycerol is a saturated diacylglycerol and a weak second messenger for the activation of PKC [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 60562-16-5. Pack Sizes: 100 mg. Product ID: HY-128468.
1,2-Dimyristoyl-sn-glycerol-3-(5?-diphosphocytidine) Dipotassium Salt
1,2-Dimyristoyl-sn-glycerol-3-(5?-diphosphocytidine) is a derivative of 1,2-Dimyristoyl-sn-glycerol (D479825) which is a saturated diacylglycerol (DAG). 1,2-Dimyristoyl-sn-glycerol is a possible weak second messenger for the activation of the PKC. Group: Biochemicals. Grades: Highly Purified. CAS No. 138879-82-0. Pack Sizes: 500ug, 1mg. Molecular Formula: C40H71K2N3O15P2, Molecular Weight: 974.15. US Biological Life Sciences.
Worldwide
1,2-Dioleoyl-sn-glycerol
ALN29882 is a glycerolipid located on the plasma membrane. It consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 18:1 DG has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. It is also used as a substrate in the DGAT-1 enzyme assay to evaluate compounds as potential inhibitors of DGAT-1. Suitable for lipoprotein overlay screening assays with the recombinant protein His-AtROP6. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: sn-1,2-Dioleoylglycerol. CAS No. 24529-88-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-141572.
1,3-Dioleoyl-rac-glycerol
1,3-Dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at the sn-1 and sn-3 positions. It activates protein kinase C (PKC) by approximately 30% when used at a concentration of 50 μM. It was used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents. Synonyms: 2-Hydroxy-1,3-propanediyl dioleate; Glycerol 1,3-dioleate; 1,3-Diolein. Grades: ≥98%. CAS No. 2465-32-9. Molecular formula: C39H72O5. Mole weight: 620.99.
1,3-Dipalmitoyl-rac-glycerol
1,3-Dipalmitoyl-rac-glycerol is a diacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions. It activates protein kinase C α (PKCα) in vitro (Ka = 3.8 μM). 1,3-Dipalmitoyl-rac-glycerol (0.25-2 μM) inhibits apoptosis and production of reactive oxygen species (ROS) and pro-inflammatory mediators induced by oxygen-glucose deprivation and reperfusion (OGD/R) in SH-SY5Y neuroblastoma cells. An acyl acceptor for the unspecific bifunctional wax ester synthase/acyl-CoA:Diacylglycerol acyltransferase. Synonyms: 1,3-Dipalmitin; Dipalmitin; 1,3-Dipalmitoyl-glycerol; Glyceryl 1,3-dipalmitate. Grades: ≥98%. CAS No. 502-52-3. Molecular formula: C35H68O5. Mole weight: 568.91.
16:0-18:1 DG
1-palmitoyl-2-oleoyl-sn-glycerol In biochemical signaling, diacylglycerol (DAG) functions as a second messenger signaling lipid and is a product of the hydrolysis of the phospholipid PIP2(phosphatidylinositol bisphosphate) by the enzyme phospholipase C (PLC) (a membrane-bound enzyme) that, through the same reaction, produces inositol trisphosphate (IP3). Group: Neutral lipids. Alternative Names: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol DG(16:0/18:1(9Z)/0:0). CAS No. 29541-66-0. Molecular formula: C37H70O5. Mole weight: 594.949. Purity: >99%. Catalog: ACM29541660.
18:0-22:6 DG
1-stearoyl-2-docosahexaenoyl-sn-glycerol In biochemical signaling, diacylglycerol (DAG) functions as a second messenger signaling lipid and is a product of the hydrolysis of the phospholipid PIP2(phosphatidylinositol bisphosphate) by the enzyme phospholipase C (PLC) (a membrane-bound enzyme) that, through the same reaction, produces inositol trisphosphate (IP3). Group: Neutral lipids. Alternative Names: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol DG(18:0/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z)/0:0). CAS No. 65886-80-8. Molecular formula: C43H72O5. Mole weight: 669.029. Purity: >99%. Catalog: ACM65886808.
A number of acyl-CoAs can act as acyl donor; maximum activity is obtained with linoleoyl-CoA. Not identical with EC 2.3.1.20 diacylglycerol O-acyltransferase. Group: Enzymes. Synonyms: 1-hexadecyl-2-acetylglycerol acyltransferase. Enzyme Commission Number: EC 2.3.1.125. CAS No. 114704-90-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2062; 1-alkyl-2-acetylglycerol O-acyltransferase; EC 2.3.1.125; 114704-90-4; 1-hexadecyl-2-acetylglycerol acyltransferase. Cat No: EXWM-2062.
1-Oleoyl-2-acetyl-sn-glycerol
1-Oleoyl-2-acetyl-sn glycerol is a synthetic, cell permeable diacylglycerol analog. 1-Oleoyl-2-acetyl-sn glycerol activates calcium-dependent protein kinase C (PKC) and induces the superoxide-production. Uses: Scientific research. Group: Signaling pathways. CAS No. 86390-77-4. Pack Sizes: 5 mg (25.09 mM * 500 μL in Acetonitrile); 10 mg (25.09 mM * 1 mL in Acetonitrile); 25 mg (25.09 mM * 2.5 mL in Acetonitrile). Product ID: HY-131648.
1-Oleoyl lysophosphatidic acid
1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase. Synonyms: 1-Oleoyl-sn-glycerol 3-phosphate; Oleoyl LPA; 18:1 LPA; 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate; LysoPA(18:1). Grades: ≥95%. CAS No. 65528-98-5. Molecular formula: C21H41O7P. Mole weight: 436.50.
1-Palmito-2-stearin
1-Palmito-2-stearin is a diacylglycerol used to increase the activity of the ARF1 GTPase-activating protein on membrane-bound ARF1GTP. Group: Biochemicals. Grades: Highly Purified. CAS No. 20296-26-8. Pack Sizes: 10mg, 100mg. Molecular Formula: C37H72O5. US Biological Life Sciences.
Worldwide
1-Palmito-2-stearin-d5
1-Palmito-2-stearin-d5 is labelled 1-Palmito-2-stearin (P144980) which is a diacylglycerol used to increase the activity of the ARF1 GTPase-activating protein on membrane-bound ARF1GTP. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C37H67D5O5, Molecular Weight: 602. US Biological Life Sciences.
Worldwide
1-Palmitoyl-2-oleoyl-rac-glycerol-d5
1-Palmitoyl-2-oleoyl-rac-glycerol-d5 is labelled 1-Palmitoyl-2-oleoyl-rac-glycerol (P160950) which is a monounsaturated diacylglycerol used to increase the activity of the ARF1 GTPase-activating protein on membrane-bound ARF1GTP. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C37H65D5O5, Molecular Weight: 599.98. US Biological Life Sciences.
Worldwide
1-Palmitoyl-d9-2-Palmitoyl-sn-glycerol
1-Palmitoyl-d9-2-palmitoyl-sn-glycerol is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycerol by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that contains palmitic acid at the sn-1 and sn-2 positions. It activates protein kinase C (PKC) by 15% when used at a concentration of 25 μM. Synonyms: 1,2-Dipalmitoyl-sn-glycerol-d9; DG(16:0-d9/16:0/0:0). Grades: ≥99% atom D. CAS No. 1872379-48-0. Molecular formula: C35H59D9O5. Mole weight: 578.
1-Stearo-2-linolein
1-Stearo-2-linolein is used in the study of the influence of platelet-derived growth factor (PDGF) on diacylglycerol phosphorylation in Swiss 3T3 cells. It is also a possible protein kinase C activator. Group: Biochemicals. Grades: Highly Purified. CAS No. 27095-10-9. Pack Sizes: 10mg, 100mg. Molecular Formula: C39H72O5, Molecular Weight: 620.99. US Biological Life Sciences.
Worldwide
1-Stearo-2-linolein-d5
1-Stearo-2-linolein-d5 is labelled 1-Stearo-2-linolein (S686465) which is used in the study of the influence of platelet-derived growth factor (PDGF) on diacylglycerol phosphorylation in Swiss 3T3 cells. It is also a possible protein kinase C activator. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C39H67D5O5, Molecular Weight: 626.02. US Biological Life Sciences.
Worldwide
1-Stearo-3-linolein
1-Stearo-3-linolein is a diacylglycerol from soybean oil deodoriser distillate. Group: Biochemicals. Grades: Highly Purified. CAS No. 126301-96-0. Pack Sizes: 10mg, 100mg. Molecular Formula: C39H72O5, Molecular Weight: 620.99. US Biological Life Sciences.
Worldwide
1-Stearo-3-linolein-d5
1-Stearo-3-linolein-d5 is labelled 1-Stearo-3-linolein (S686455) which is a diacylglycerol from soybean oil deodoriser distillate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C39H67D5O5, Molecular Weight: 626.02. US Biological Life Sciences.
Worldwide
1-Stearoyl-2-linoleoyl-sn-glycerol
1-Stearoyl-2-linoleoyl-sn-glycerol is used in the study of the influence of platelet-derived growth factor (PDGF) on diacylglycerol phosphorylation in Swiss 3T3 cells. It is also a possible protein kinase C activator. Group: Biochemicals. Grades: Highly Purified. CAS No. 34487-26-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C39H72O5, Molecular Weight: 620.99. US Biological Life Sciences.
1-tert-Butyl 3-Methyl 5-Hydroxypiperidine-1,3-dicarboxylate is an intermediate used in the synthesis of heterocyclyl aminopyrazine derivatives for use as CHK-1 inhibitors. It is also used to prepare pyrrolidinyl imidazopyridinyl piperidinyl methanone derivatives and analogs for use as diacylglycerol acyltransferase 2 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1095010-47-1. Pack Sizes: 50mg, 250mg. Molecular Formula: C12H21NO5, Molecular Weight: 259.3. US Biological Life Sciences.
Worldwide
2- (2, 3-Diazidopropoxy) tetrahydro-2H-pyran
2- (2, 3-diazidopropoxy) tetrahydro-2H-pyran is an intermediate in the synthesis of diacylglycerol analogs as potential second-messenger antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 52438-81-0. Pack Sizes: 25mg, 100mg. Molecular Formula: C8H14N6O2. US Biological Life Sciences.
Worldwide
2- (2, 3-Dibromopropoxy) tetrahydro-2H-pyran
2- (2, 3-Dibromopropoxy) tetrahydro-2H-pyran is an intermediate in the synthesis of diacylglycerol analogs as potential second-messenger antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 52393-58-5. Pack Sizes: 25mg, 100mg. Molecular Formula: C8H14Br2O2. US Biological Life Sciences.
Worldwide
2,3-Diaminopropyl Tetrahydropyranyl Ether
2,3-Diaminopropyl Tetrahydropyranyl Ether is an intermediate in the synthesis of diacylglycerol analogs as potential second-messenger antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 101857-33-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C8H18N2O2. US Biological Life Sciences.
Worldwide
2-Bromopropionyl Chloride
2-Bromopropionyl chloride is a reagent that is used in the preparation of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase 1. Group: Biochemicals. Grades: Highly Purified. CAS No. 7148-74-5. Pack Sizes: 1g, 10g. Molecular Formula: C3H4BrClO, Molecular Weight: 171.42. US Biological Life Sciences.
ABT-046 is a potent, selective, and orally bioavailable Diacylglycerol acyltransferase 1 (DGAT-1 ) inhibitor (IC50=8 nM). Synonyms: ABT-046; ABT 046; ABT046. Grades: >98%. CAS No. 1031336-60-3. Molecular formula: C20H22N4O2. Mole weight: 350.41.
acyloxyacyl hydrolase
The substrate is lipid A on the reducing end of the toxic lipopolysaccharide (LPS) of Salmonella typhimurium and related organisms. It consists of diglucosamine, β-D-GlcN-(1? 6)-D-GlcN, attached by glycosylation on O-6 of its non-reducing residue, phosphorylated on O-4 of this residue and on O-1 of its potentially reducing residue. Both residues carry 3-(acyloxy)acyl groups on N-2 and O-3. The enzyme from human leucocytes detoxifies the lipid by hydrolysing the secondary acyl groups from O-3 of the 3-hydroxyacyl groups on the disaccharide (LPS). It also possesses a wide range of phospholipase and acyltransferase activities [e.g. EC 3.1.1.4 (phospholipase A2), EC 3.1.1.5 (lysophospholipase), EC 3.1.1.32 (phospholipase A1) and EC 3.1.1.52 (phosphatidylinositol deacylase)], hydrolysing diacylglycerol and phosphatidyl compounds, but not triacylglycerols. It has a preference for saturated C12-C16 acyl groups. Group: Enzymes. Enzyme Commission Number: EC 3.1.1.77. CAS No. 110277-64-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3505; acyloxyacyl hydrolase; EC 3.1.1.77; 110277-64-0. Cat No: EXWM-3505.
Alkaline Lipase for detergent
Lipase is a kind of enzyme preparation produced by aspergillus submerged fermentation. It is also a kind of modified enzyme preparation after DNA recombination. The main activated composition lipase can hydrolyze grease into dihydroxypropyl ester/ diacylglycerol/ glycerin/free fatty acid. Applications: Lipase can effectively reduce hydrophobicity of grease and fat and remove dirt. at 20°c lipase can improve washing effcet lipase can decompose butter dirt or fat dirt on fibre. Group: Enzymes. Synonyms: Alkaline Lipase; for detergent; Lipase; reduce hydrophobicity of grease; Detergent Enzymes; Detergents; Alkaline Lipase for detergent; DETE-2624. CAS No. 9001-62-1. Alkaline Lipase. Appearance: powder or liquid. Source: Aspergillus. Alkaline Lipase; for detergent; Lipase; reduce hydrophobicity of grease; Detergent Enzymes; Detergents; Alkaline Lipase for detergent; DETE-2624. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: DETE-2624.
AZD 3988
AZD 3988 is a selective and potent diacylglycerol O-acyltransferase (DGAT) enzyme inhibitor with IC50 value of 0.6 nM. It is selective for DGAT-1 over DGAT-2, cytochrome P450 enzymes and Kv11.1 (hERG). It suppresses adipose tissue TAG synthesis and triacylglyceride (TAG) plasma excursion in rats. It reduces body weight of diet-induced obese rats and may be used as a potential treatment for diabetes and other metabolic diseases. It is orally bioavailable and cell permeable. Synonyms: AZD 3988; AZD-3988; AZD3988; trans-4- [- [ [ [5- [ (3, 4-Difluorophenyl) amino] -1, 3, 4-oxadiazol-2-yl] carbonyl] amino] phenyl] cyclohexaneacetic acid. Grades: ≥98% by HPLC. CAS No. 892489-52-0. Molecular formula: C23H22F2N4O4. Mole weight: 456.44.
Chemically modified Pseudomonas species Lipoprotein Lipase
Enzyme that hydrolyzes triglycerides into three free fatty acids and glycerol. Take advantage of the enhanced liquid stability of this enzyme. Rely on the proven diagnostic quality of this product. Applications: Use lipoprotein lipase in diagnostic tests for the determination of triglycerides together with glycerol kinase and glycerol-3-phosphate dehydrogenase. Group: Enzymes. Synonyms: Lipoprotein lipase; LPL; Clearing factor lipase; Diacylglycerol lipase; Diglyceride lipase. LPL. Mole weight: 47 kD. Activity: >10 U/mg lyophilizate. Stability: At +2 to +8°C within specification range for 12 months. Store dry. Appearance: Brownish lyophilizate. Source: Pseudomonas species. Lipoprotein lipase; LPL; EC 3.1.1.34; Clearing factor lipase; Diacylglycerol lipase; Diglyceride lipase. Cat No: DIA-282.
Choline tosylate
Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG) [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Choline p-toluenesulfonate. CAS No. 55357-38-5. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W100403.
Cochlioquinone A (Luteoleersin)
Cochlioquinone A is the major component of a bioactive pigment isolated from Bipolaris leersia. Cochlioquinone A has been recently shown to be an antagonist of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1). It is anti-angiogenic and exhibits inhibitory activity against diacylglycerol acyltransferase and NADH-ubiquinone reductase. Group: Biochemicals. Alternative Names: Luteoleersin. Grades: Highly Purified. CAS No. 32450-25-2. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Cochlioquinone B
Cochlioquinone B, the minor component of a bioactive pigment isolated from Bipolaris leersia, is an NADH-ubiquinone reductase inhibitor and a phytotoxic agent inhibiting root growth. It is closely related to Cochlioquinone A that inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. Cochlioquinones have been recently shown to be antagonists of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1). Group: Biochemicals. Grades: Highly Purified. CAS No. 32450-26-3. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Cochlioquinone B
It is the minor component of a bioactive pigment isolated from Bipolaris cynodontis and Cochliobolus miyabeanus. It is an NADH-ubiquinone reductase inhibitor. It is also a phytotoxic agent inhibiting root growth. It is closely related to cochlioquinone A which inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. It is an antagonist of the human chemokine receptor, CCR5, in HIV-1. Synonyms: 20-De(acetyloxy)-11-deoxy-20-oxo-cochlioquinone A; 9-(1, 3-Dimethyl-2-oxopentyl)-1, 2, 3, 4aα, 5, 6, 6a, 12, 12aα, 12b-decahydro-3β-(1-hydroxy-1-methylethyl)-6aβ, 12bβ-dimethyl-pyrano[3, 2-a]xanthene-8, 11-dione Stereoisomer; (3R,4aR,6aR,12aR,12bR)-9-[(1S,3S)-1,3-Dimethyl-2-oxopentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethylpyrano[3,2-a]xanthene-8,11-dione. Grades: >99% by HPLC. CAS No. 32450-26-3. Molecular formula: C28H40O6. Mole weight: 472.61.
DGAT1-IN-1
Imidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparation. Synonyms: DGAT1-IN-1; DGAT1 IN 1. Grades: >98%. CAS No. 1449779-49-0. Molecular formula: C30H28F3N3O4. Mole weight: 551.56.
Dimyristin
Dimyristin is a diacylglycerol. Synonyms: 3-hydroxypropane-1,2-diyl ditetradecanoate; 1,2-Dimyristoyl-rac-glycerol; 1,2-Dimyristin; Glycerol dimyristate; D-alpha,beta-Dimyristin. Grades: >95% by HPLC. CAS No. 53563-63-6. Molecular formula: C31H60O5. Mole weight: 512.80.
Dioctanoylglycol
Dioctanoylglycol (Ethylene glycol dicaprylate), a diacylglycerol analog, is a diacylglycerol kinase (DGK) inhibitor ( K i of 58 μM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ethylene glycol dicaprylate; Ethylene glycol dioctanoate; Ethylenedioctanoate. CAS No. 627-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100960.
Dioctanoylglycol
Dioctanoylglycol has been found to be a diacylglycerol kinase (DGK) inhibitor. Synonyms: Dioctanoyl ethylene glycol; 2-Octanoyloxyethyl octanoate. Grades: ≥95% by HPLC. CAS No. 627-86-1. Molecular formula: C18H34O4. Mole weight: 314.46.
Dipalmitin
Dipalmitin is an active product that can be extracted from root tuber of Typhonium giganteum Engl. Dipalmitin is a diacylglycerol that contains the saturated 16-carbon fatty acid Palmitic acid (HY-N0830) at two positions [1]. Uses: Scientific research. Group: Natural products. CAS No. 26657-95-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N7399.
Eicosapentaenoic acid methyl ester
Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis) [1]. Uses: Scientific research. Group: Natural products. CAS No. 2734-47-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011311.
ethanolaminephosphotransferase
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. This enzyme participates in 3 metabolic pathways: aminophosphonate metabolism, glycerophospholipid metabolism, and ether lipid metabolism. Group: Enzymes. Synonyms: EPT; diacylglycerol ethanolaminephosphotransferase; CDPethanolamine diglyceride phosphotransferase; phosphorylethanolamine-glyceride transferase; CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase. Enzyme Commission Number: EC 2.7.8.1. CAS No. 9026-19-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3309; ethanolaminephosphotransferase; EC 2.7.8.1; 9026-19-1; EPT; diacylglycerol ethanolaminephosphotransferase; CDPethanolamine diglyceride phosphotransferase; phosphorylethanolamine-glyceride transferase; CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase. Cat No: EXWM-3309.
Ethyl Isobutyrylacetate
Ethyl Isobutyrylacetate is used in the synthesis of piperazine derivatives as possible multireceptor atypical antipsychotics, affecting dopamine and serotonin receptor properties. Also used in the synthesis of pyrazinecarboxamide DGAT1 (diacylglycerol acyltransferase 1) inhibitors used in the treatment of obesity. Group: Biochemicals. Alternative Names: 3-Oxo-4-methylpentanoic Acid Ethyl Ester; 4-Methyl-3-oxo-pentanoic Acid Ethyl Ester; 4-Methyl-3-oxovaleric Acid Ethyl Ester; Ethyl 2-isobutyrylacetate; Ethyl 3-Isopropyl-3-oxopropanoate; Ethyl 3-oxo-4-methylpentanoate; Ethyl 3-Oxo-4-methylvalerate; Ethyl 4-Methyl-3-oxopentanoate; Ethyl 4-Methyl-3-oxovalerate; Ethyl Isobutyrylacetate; Isobutyrylacetic Acid Ethyl Ester; NSC 62029; γ,γ-Dimethylacetoacetic Acid Ethyl Ester; Ethyl 4-Methyl-3-oxopentanoate. Grades: Highly Purified. CAS No. 7152-15-0. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Glycerol-d5 1,3-Dipalmitate
A glycidol fatty acid esters in edible oils. An acyl acceptor for the unspecific bifunctional wax ester synthase/acyl-CoA:Diacylglycerol acyltransferase. Group: Biochemicals. Alternative Names: 1,3-Dipalmitin-d5; 1,3-Dipalmitoylglycerin-d5; 1,3-Dipalmitoylglycerol-d5; Glycerol-d5 1,3-Dihexadecanoate; Hexadecanoic-d5 Acid 2-Hydroxy-1,3-propanediyl Ester. Grades: Highly Purified. CAS No. 65615-82-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Glyceryl Monostearate
While the names glyceryl monostearate and mono- and diglycerides are used for a variety of esters of long-chain fatty acids, the esters fall into two distinct grades: 40-55 percent monoglycerides The PhEur describes glyceryl monostearate 40-55 as a mixture of monoacylglycerols, mostly monostearoylglycerol, together with quantities of di- and triacylglycerols. It contains 40-55% of monoacylglycerols, 30-45% of diacylglycerols, and 5-15% of triacylglycerols. Synonyms: Capmul GMS-50; Cutina GMS; 2, 3-dihydroxypropyl octadecanoate; Geleol; glycerine monostearate; glycerin monostearate; glycerol monostearate; glyceroli monostearas; glycerol stearate; glyceryl stearate; GMS; HallStar GMS; Imwitor 191; Imwitor 900; Kessco GMS; Lipo GMS; monoester with 1, 2, 3-propanetriol; monostearin; Myvaplex 600P; Myvatex; 1, 2, 3-propanetriol octadecanoate; Protachem GMS-450; Ri. CAS No. 31566-31-1. Product ID: PE-0518. Molecular formula: C21H42O4. Mole weight: 358.6. Category: Emollient; Emulsifying Agents; Solubilizing Agents; Stabilizing Agents; Sustained-release Agents; Tablet and Capsule Lubricant. Product Keywords: Emulsifier Excipients; Solubilizer Excipients; PE-0518; Glyceryl Monostearate; Emollient; Emulsifying Agents; Solubilizing Agents; Stabilizing Agents; Sustained-release Agents; Tablet and Capsule Lubricant; C21H42O4; 31566-31-1. UNII: NA. Chemical Name: Octadecanoic acid, monoester with 1, 2, 3-propanetriol. Gra
glycosylphosphatidylinositol phospholipase D
This enzyme is also active when O-4 of the glucosamine is substituted by carrying the oligosaccharide that can link a protein to the structure. It therefore cleaves proteins from the lipid part of the glycosylphosphatidylinositol (GPI) anchors, but does so by hydrolysis, whereas glycosylphosphatidylinositol diacylglycerol-lyase (EC 4.6.1.14) does so by elimination. It acts on plasma membranes only after solubilization of the substrate with detergents or solvents, but it may act on intracellular membranes. Group: Enzymes. Synonyms: GPI-PLD; glycoprotein phospholipase D; phosphatidylinositol phospholipase D; phosphatidylinositol-specific phospholipase D. Enzyme Commission Number: EC 3.1.4.50. CAS No. 113756-14-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3733; glycosylphosphatidylinositol phospholipase D; EC 3.1.4.50; 113756-14-2; GPI-PLD; glycoprotein phospholipase D; phosphatidylinositol phospholipase D; phosphatidylinositol-specific phospholipase D. Cat No: EXWM-3733.
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