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| Product | Description | |
|---|---|---|
| Dimethyl fumarate | Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 624-49-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-17363. |  |
| Dimethyl fumarate | Dimethyl fumarate. Group: Biochemicals. Alternative Names: Fumaric acid dimethyl ester. Grades: Highly Purified. CAS No. 624-49-7. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C6H8O4. US Biological Life Sciences. |  Worldwide |
| Dimethyl Fumarate | White crystals, 98%. CAS No. 624-49-7. Pack Sizes: 100g, 500g. Product ID: FR-1080. M.P. 103-104. Mole weight: 144.13. |  Frinton Laboratories |
| 2- ( ( (5- ( (Dimethylamino) methyl) furan-2-yl) methyl) thio) ethanamine Fumarate (2:1) | 2- ( ( (5- ( (Dimethylamino) methyl) furan-2-yl) methyl) thio) ethanamine (E)-2-Butenedioate is an impurity of Ranitidine (R120000), a histamine H2-receptor antagonist which inhibits gastric acid secretion. Antiulcerative. Group: Biochemicals. Grades: Highly Purified. CAS No. 256948-32-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C20H36N4O2S2 C4H4O4. US Biological Life Sciences. | Worldwide |
| 3-(4-Chlorobenzyl)-1-(dimethylamino)pentan-3-ol Fumarate Salt | 3-(4-Chlorobenzyl)-1-(dimethylamino)pentan-3-ol Fumarate Salt is a useful synthetic intermediate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C14H22ClNO; (C4H4O4), Molecular Weight: 255.781160699999. US Biological Life Sciences. | Worldwide |
| Dimethylaminocarboxymethyl POC Tenofovir Fumarate | One impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Grades: > 95%. Molecular formula: C18H29N6O9P. C4H4O4. Mole weight: 620.51. |  |
| Dimethyl dihydroxyfumarate | Dimethyl dihydroxyfumarate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: methyl (Z)-3,4-dihydroxy-4-methoxy-2-oxo-but-3-enoate;(E)-2,3-Dihydroxy-2-butenedioic acid dimethyl ester;Dimethyl dihydroxyfumarate;Methyl 3,4-dihydroxy-4-methoxy-2-oxobut-3-enoate;Dihydroxyfumaric acid dimethyl ester;Fumaric acid, dihydroxy-, dimethyl. Product Category: Heterocyclic Organic Compound. CAS No. 133-47-1. Molecular formula: C6H8O6. Mole weight: 176.12. Density: 1.434. Product ID: ACM133471. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Oxytocin Receptor Antagonist, MSC1630296 (OT-R Antagonist, 3- (4- (N- (4-chlorophenyl) -N- (2-oxo-2- (2- (2-oxoindolin-3-ylidene) hydrazinyl) ethyl) sulfamoyl) phenyl) -N- (3- (dimethylamino) propyl) propanamide, Fumarate Salt) | A tertiary sulfonamide-based compound that acts as a high-affinity oxytocin (OT) receptor-selective antagonist (Ki = 650 and 670pM in 125I-OVTA-competitive binding assays using human and rat OT-R, respectively), while displaying 65-, 245-, and 23,000-fold reduced affinity, respectively, toward human vassopressin receptors V1a, V2, and V1b. Shown to effectively inhibit OT- (10nM) induced Ca2+ mobilization in hOT-R-expressing HEK293-EBNA cells (IC50 = 14nM) in vitro and OT-stimulated uterine contractions in rats (1.4 -10mg/kg p.o. or 30mg/kg p.o.) in vivo. Product is supplied as a fumarate salt for enhanced aqueous solubility (20 and 10mg/ml, respectively, in water and HBSS). Group: Biochemicals. Grades: Purified. Pack Sizes: 2mg. Molecular Formula: C??H??ClN?O?S.C?H?O?. US Biological Life Sciences. | Worldwide |
| 4-Chloro bupropion fumarate | 4-Chloro bupropion fumarate. Group: Biochemicals. Alternative Names: 1-(3,4-Dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone (2E)-2-butenedioate. Grades: Highly Purified. CAS No. 1193779-36-0. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C17H21Cl2NO5. US Biological Life Sciences. | Worldwide |
| 4-Chloro Bupropion Fumarate | 4-Chloro Bupropion Fumarate is a derivative of Bupropion, which is a selective dopamine uptake inhibitor used in the treatment of depression and smoking cessation. Synonyms: 1-(3,4-Dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone (2E)-2-Butenedioate; 1-(3,4-Dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]-1-propanone (2E)-2-butenedioate (1:1); 1-Propanone, 1-(3,4-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-, (2E)-2-butenedioate (1:1). Grades: 95%. CAS No. 1193779-36-0. Molecular formula: C17H21Cl2NO5. Mole weight: 390.26. | |
| 5-Chloro bupropion fumarate | 5-Chloro bupropion fumarate. Group: Biochemicals. Alternative Names: 1-(3,5-Dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone (2E)-2-butenedioate. Grades: Highly Purified. CAS No. 1193779-50-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C17H21Cl2NO5. US Biological Life Sciences. | Worldwide |
| 5-Chloro Bupropion Fumarate | 5-Chloro Bupropion Fumarate is a derivative of Bupropion, which is a selective dopamine uptake inhibitor used in the treatment of depression and smoking cessation. Synonyms: 1-(3,5-Dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone (2E)-2-Butenedioate; 1-(3,5-Dichlorophenyl)-2-[(2-methyl-2-propanyl)amino]-1-propanone (2E)-2-butenedioate (1:1); 1-Propanone, 1-(3,5-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-, (2E)-2-butenedioate (1:1). Grades: 98%. CAS No. 1193779-50-8. Molecular formula: C17H21Cl2NO5. Mole weight: 390.26. | |
| Atpenin A5 | Antibiotic. Antifungal. Potent and specific mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor. Mitochondrial ATP-sensitive potassium (mK(ATP)) channel activator. Cardioprotective. Modulates mitochondrial ROS generation during cardioprotection.The IC50 value against bovine heart complex II is 3.6nM (which is ~300-fold lower than the IC50 value of carboxin (1.1uM)). It also inhibits fumarate reductase of Ascaris suum (IC50 = 12nM). Inhibition of E. coli succinate dehydrogenase is less potent (IC50 = 5uM). By co-crystallization studies of atpenin A5 and complex II, the binding site of atpenin A5 was found to be the quinone-binding site of complex II. Additionally, atpenin A5 has been shown to have a protective action against ischemia-reperfusion via the activation of mitochondrial KATP channels. Group: Biochemicals. Alternative Names: 3-[(2S,4S,5R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1H)-pyridinone. Grades: Highly Purified. CAS No. 119509-24-9. Pack Sizes: 250ug, 1mg. Molecular Formula: C15H21Cl2NO5. US Biological Life Sciences. | Worldwide |
| Bedaquiline fumarate | Bedaquiline fumarate is an anti-tuberculosis drug which selectively inhibits the mycobacterial energy metabolism and found to be effective against all states of Mycobacterium tuberculosis. It possesses a unique mechanism of action that disrupts the activity of the mycobacterial adenosine triphosphate synthase. It has an excellent in vitro activity against Mycobacterium tuberculosis, including multidrug resistant M tuberculosis, however, its side effect profile limits its use against MDR-TB when no other effective regimen can be provided. Uses: Antitubercular agents. Synonyms: (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol fumarate. Grades: >98%. CAS No. 845533-86-0. Molecular formula: C36H35BrN2O6. Mole weight: 671.58. | |
| dihydroorotate dehydrogenase (quinone) | This Class 2 dihydroorotate dehydrogenase enzyme contains FMN. The enzyme is found in eukaryotes in the mitochondrial membrane, in cyanobacteria, and in some Gram-negative and Gram-positive bacteria associated with the cytoplasmic membrane. The reaction is the only redox reaction in the de-novo biosynthesis of pyrimidine nucleotides. The best quinone electron acceptors for the enzyme from bovine liver are ubiquinone-6 and ubiquinone-7, although simple quinones, such as benzoquinone, can also act as acceptor at lower rates. Methyl-, ethyl-, tert-butyl and benzyl (S)-dihydroorotates are also substrates, but methyl esters of (S)-1-methyl and (S)-3-methyl and (S)-1,3-dimethyldihydroorotates are not. Class 1 dihydroorotate dehydrogenases use either fumarate (EC 1.3.98.1), NAD+ (EC 1.3.1.14) or NADP+ (EC 1.3.1.15) as electron acceptor. Group: Enzymes. Synonyms: dihydroorot. Enzyme Commission Number: EC 1.3.5.2. CAS No. 59088-23-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1386; dihydroorotate dehydrogenase (quinone); EC 1.3.5.2; 59088-23-2; dihydroorotate:ubiquinone oxidoreductase; (S)-dihydroorotate:(acceptor) oxidoreductase; (S)-dihydroorotate:acceptor oxidoreductase; DHOdehase (ambiguous); DHOD (ambiguous); DHODase (ambiguous); DHODH. Cat No: EXWM-1386. |  |
| Diroximel fumarate | Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALKS 8700; BIIB098. CAS No. 1577222-14-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100375. | |
| Fumarprotocetraric acid | Fumarprotocetraric acid is originally isolated from Cetraria islandica. Synonyms: Fumarylprotocetraric acid; NSC-249984; NCGC00095467-02; [(7-carboxy-4-formyl-3,8-dihydroxy-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-9-yl)methyl] hydrogen fumarate. Grades: >95%. CAS No. 489-50-9. Molecular formula: C22H16O12. Mole weight: 472.35. | |
| mono-Methyl fumarate | Monomethyl Fumarate is one of the most bioactive anti-psoriatic fumaric acid ester metabolite. It is potent nicotinic acid receptor agonist. It has also been shown to selectively stimulate of T helper 2 cytokine response. Uses: Fumaric acid monomethyl ester is one of the most bioactive anti-psoriatic fumaric acid ester metabolite. fumaric acid monomethyl ester is potent nicotinic acid receptor agonist. fumaric acid monomethyl ester has also been shown to selectively stimulate of t helper 2 cytokine response. it is also the active metabolite of dimethyl fumarate (d464965), a compound that is used as a treatment for the relapsing forms of multiple sclerosis and psoriasis. Synonyms: (E)-4-methoxy-4-oxobut-2-enoic acid. Grades: > 95 %. CAS No. 2756-87-8. Molecular formula: C5H6O4. Mole weight: 130.10. | |
| Monomethyl fumarate | Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2756-87-8. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-103252. | |
| O-Acetyl Psilocin-d4 Fumarate | O-Acetyl Psilocin-d4 Fumarate. Group: Biochemicals. Alternative Names: 3-[2-(Dimethylamino)ethyl-d4]-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Pyrilamine maleate salt | Pyrilamine maleate salt is a first generation antihistamine and binds with high affinity to G(q/11) protein. It is commonly utilized as a radioligand binding assay for the H1 receptor. It also has anticholinergic properties. It is used in over-the-counter combination products to treat the common cold and menstrual symptoms. It is also the active ingredient of the topical antihistamine creams Anthisan and Neoantergan. It is also found to be a potent inhibitor of CYP2D6 in hepatocytes. It has been listed. Uses: Pyrilamine maleate salt is commonly utilized as a radioligand binding assay for the h1 receptor. it also has anticholinergic properties. it is used in over-the-counter combination products to treat the common cold and menstrual symptoms. Synonyms: N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine fumarate;Diaminide maleate;(Z)-but-2-enedioic acid;N-[(4-Methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl- 1,2-ethanediamine (2Z)-2-Butenedioate;Paraminyl Maleate. Grades: 95%. CAS No. 59-33-6. Molecular formula: C21H27N3O5. Mole weight: 401.46. | |
| Ranitidine Related Compound A | An impurity of Ramipril, an ACE inhibitor that can be used to treat hypertension. Synonyms: 2-(((5-((Dimethylamino)methyl)furan-2-yl)methyl)thio)ethanamine fumarate. CAS No. 91224-69-0. Molecular formula: C14H22N2O5S. Mole weight: 330.40. | |
| Sartorypyrone D | Sartorypyrone D is a fungal metabolite originally isolated from N. fischeri. It inhibits NADH fumarate reductase (NFRD; IC50=1.7 μM in A. suum mitochondria) and NADH oxidase (IC50 = 3 μM in bovine heart mitochondria). Synonyms: 2,2-Dimethyl-3alpha-[(3E,7E)-3,7-dimethyl-9-(2-oxo-4-hydroxy-6-methyl-2H-pyran-3-yl)-3,7-nonadienyl]-4-methylenecyclohexane-1alpha-ol. Grades: >95% by HPLC. CAS No. 1801167-48-5. Molecular formula: C26H38O4. Mole weight: 414.58. | |
| tert-Butyl ethylfumarate | tert-Butyl ethylfumarate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 100922-16-5, 2-Butenedioic acid(2E)-, 1-(1,1-dimethylethyl) 4-ethyl ester, ACMC-20m3yv, TERT-BUTYLETHYLFUMARATE, CTK3J9359, AG-D-06843, 2-Butenedioicacid (2E)-, 1,1-dimethylethyl ethyl ester (9CI); 2-Butenedioic acid (E)-,1,1-dimethylethyl ethyl ester; (E)-tert-Butyl ethyl butenedioate; Fumaric acidtert-butyl ethyl ester; tert-Butyl ethyl fumarate. Product Category: Heterocyclic Organic Compound. CAS No. 100922-16-5. Molecular formula: C10H14O4-2. Mole weight: 198.215760 [g/mol]. Purity: 0.96. IUPACName: 2-tert-butyl-3-ethylbut-2-enedioate. Canonical SMILES: CCC(=C(C(=O)[O-])C(C)(C)C)C(=O)[O-]. Product ID: ACM100922165. Alfa Chemistry ISO 9001:2015 Certified. | |
| trans-1,2-Ethylenedicarboxylic Acid | trans-1,2-Ethylenedicarboxylic Acid. Group: Biochemicals. Alternative Names: (2E)-2-Butenedioic Acid 1,4-Dimethyl Ester; (E)-2-Butenedioic Acid 1,4-Dimethyl Ester; Fumaric Acid Dimethyl Ester; (2E)-2-Butenedioic Acid Dimethyl Ester; (E)-But-2-enedioic Acid Dimethyl Ester; AZL-O 211089; Allomaleic Acid Dimethyl Ester; BG 00012; Boletic Acid Dimethyl Ester; Dimethyl (E)-2-Butenedioate; Dimethyl (E)-Butenedioate; Dimethyl Fumarate; Dimethyl trans-Ethylenedicarboxylate; Methyl Fumarate; NSC 167432; NSC 25942; trans-1,2-Ethylenedicarboxylic Acid Dimethyl Ester; trans-Butenedioic Acid Dimethyl Ester. Grades: Highly Purified. CAS No. 624-49-7. Pack Sizes: 10g. Molecular Formula: C6H8O4, Molecular Weight: 144.13. US Biological Life Sciences. | Worldwide |
| Fumaraldehyde bis(dimethyl acetal) | Fumaraldehyde bis(dimethyl acetal). Uses: Designed for use in research and industrial production. Product Category: Ortho Esters. CAS No. 6068-62-8. Molecular formula: C8H16O4. Mole weight: 176.21. Product ID: ACM6068628. Alfa Chemistry ISO 9001:2015 Certified. Categories: (2E)-1,1,4,4-tetramethoxybut-2-ene. | |
| Fumaric Acid tert-Butyl Ester | Fumaric Acid tert-Butyl Ester is a tert-Butyl ester derivative of Fumaric Acid (F500380). Fumaric Acid tert-Butyl Ester is a reactant used in the preparation of cysteine protease inhibitors based on fumaric acid-derived oligopeptides. It is also used in the preparation of Nε-fumaroylated diketopiperazine of L-Lys used for pulmonary drug delivery. Group: Biochemicals. Alternative Names: (2E)-2-Butenedioic Acid Mono(1,1-dimethylethyl) Ester; (E)-4-tert-Butoxy-4-oxobut-2-enoic Acid. Grades: Highly Purified. CAS No. 135355-96-3. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| Fumaric Acid tert-Butyl Ester | Fumaric Acid tert-Butyl Ester is a tert-butyl ester derivative of Fumaric acid, which is a drug used to treat the autoimmune condition psoriasis. It is also used as a food additive. Synonyms: (2E)-2-Butenedioic Acid Mono(1,1-dimethylethyl) Ester; (E)-4-tert-Butoxy-4-oxobut-2-enoic Acid; Fumaric acid mono-tert-butyl ester; (E)-4-(Tert-butoxy)-4-oxobut-2-enoic acid; 2-Butenedioic acid, mono(1,1-dimethylethyl)ester, (2E)-. Grades: 95%. CAS No. 135355-96-3. Molecular formula: C8H12O4. Mole weight: 172.18. | |
| N- (2-N, N-Dimethylaminoethyl) fumaramic Acid | N- (2-N, N-Dimethylaminoethyl) fumaramic Acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
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