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| Product | Description | |
|---|---|---|
| 2,3-Dimethyl-5-Vinylpyrazine | An derivative of Pyrazine.Pyrazine is a heterocyclic aromatic organic compound. Grades: > 95%. CAS No. 160818-30-4. Molecular formula: C8H10N2. Mole weight: 134.18. |  |
| 2,5-Dibromo-3,6-dimethylpyrazine | Heterocyclic Organic Compound. Alternative Names: AGN-PC-002RKL, ZINC30678583, Pyrazine, 2,5-dibromo-3,6-dimethyl-, 2,5-DIBROMO-3,6-DIMETHYLPYRAZINE, 121594-49-8. CAS No. 121594-49-8. Molecular formula: C6H6Br2N2. Mole weight: 265.933240 [g/mol]. Purity: 0.96. IUPACName: 2,5-dibromo-3,6-dimethylpyrazine. Canonical SMILES: CC1=C(N=C(C(=N1)Br)C)Br. Catalog: ACM121594498. |  |
| 2,5-Dimethylpyrazine | 2,5-Dimethylpyrazine. CAS No. 123-32-0. Pack Sizes: 100, 500 g in glass bottle. Product ID: CDC10-0167. Molecular formula: C6H8N2. Category: Flavoring Chemical Agents. Product Keywords: Cosmetic Ingredients; Flavoring Chemical Agents; 2,5-Dimethylpyrazine; CDC10-0167; 123-32-0; C6H8N2; 204-618-3; MFCD00006147; 123-32-0. Grade: Fragrance grade. Purity: ≥98%, FG. Color: Clear colorless to pale yellow. EC Number: 204-618-3. Physical State: Liquid. Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly). Quality Level: 400. Storage: Inert atmosphere,Room Temperature. Application: flavors and fragrances. Boiling Point: 155 °C (lit.). Melting Point: 15°C. Density: 0.99 g/mL at 25 °C (lit.). Product Description: 2,5-Dimethylpyrazine is a pyrazine compound that is mainly formed in food products such as cooked rice or roasted peanuts due to the Maillard reaction between sugars and proteins during cooking or roasting process. |  |
| 2,5-Dimethylpyrazine | 2,5-Dimethylpyrazine is used as a reagent in the synthesis of bone-targeted proteasome inhibitors for multiple myeloma (MM). 2,5-Dimethylpyrazine is also used in the preparation of 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340); a degredation product of Clavulanic Acid (C563750) which is a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. CAS No. 123-32-0. Pack Sizes: 5g, 25g. Molecular Formula: C6H8N2. US Biological Life Sciences. |  Worldwide |
| 2,5-Pyrazinedipropanoic Acid Dimethyl Ester | 2,5-Pyrazinedipropanoic Acid Dimethyl Ester is used in the study of pharmacological effect an chemical composition of the organic acid of Radix ranunculus ternati which has an anti-tuberculosis effect. Group: Biochemicals. Grades: Highly Purified. CAS No. 77479-01-7. Pack Sizes: 250mg, 1g. Molecular Formula: C12H16N2O4, Molecular Weight: 252.27. US Biological Life Sciences. | Worldwide |
| 2,6-Dimethyl pyrazine | 2,6-Dimethyl pyrazine. Group: Biochemicals. Grades: Highly Purified. CAS No. 108-50-9. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C6H8N2. US Biological Life Sciences. | Worldwide |
| 2-Amino-3- (dimethylamino) pyrazine | 2-Amino-3- (dimethylamino) pyrazine. Group: Biochemicals. Grades: Highly Purified. CAS No. 89488-74-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C6H10N4, Molecular Weight: 138.169999999999. US Biological Life Sciences. | Worldwide |
| 2-ethyl-3,5-dimethylpyrazine | Synonyms: Pyrazine, 2-ethyl-3,5-dimethyl-; 2,6-Dimethyl-3-ethylpyrazine; 3,5-Dimethyl-2-ethylpyrazine; 3-Ethyl-2,6-dimethylpyrazine. Grades: 95%. CAS No. 13925-07-0. Molecular formula: C8H12N2. Mole weight: 136.19. | |
| 2-Ethyl-3,6-dimethylpyrazine | 2-Ethyl-3,6-dimethylpyrazine, a flavoring constituent prevalently utilized in the food domain, exudes a roasted, nutty relish, and is frequently detected in baked items, meaty comestibles, and piquant munchies. Furthermore, its potential as an antioxidizing and anti-inflammatory agent in treating sundry diseases has captivated scientific examination. Synonyms: Pyrazine, 3-ethyl-2,5-dimethyl-; 2,5-dimethyl-3-ethylpyrazine. Grades: 98%. CAS No. 13360-65-1. Molecular formula: C8H12N2. Mole weight: 136.19. | |
| 2-Ethyl-d5-3,5-dimethylpyrazine | Isotope-labeled Flavours & Fragrances2H Labeled Compounds. CAS No. 1082581-96-1. Molecular formula: C8D5H7N2. Mole weight: 136.2. IUPACName: 3,5-dimethyl-2-(1,1,2,2,2-pentadeuterioethyl)pyrazine. Catalog: ACM1082581961. | |
| 2-Pyrazinecarboxamide,N-(1,1-dimethylethyl)- | Heterocyclic Organic Compound. Alternative Names: N-T-BUTYL PYRAZINE CARBOXAMIDE. CAS No. 121885-10-7. Molecular formula: C9H13 N3 O. Mole weight: 179.22. Purity: 0.96. IUPACName: N-tert-butylpyrazine-2-carboxamide. Canonical SMILES: CC(C)(C)NC(=O)C1=NC=CN=C1. Density: 1.081 g/cm³. Catalog: ACM121885107. | |
| 3,5-Dimethyl-2-ethylpyrazine (2-Ethyl-3,5-dimethyl-pyrazine) | 3,5-Dimethyl-2-ethylpyrazine (2-Ethyl-3,5-dimethyl-pyrazine). Group: Biochemicals. Alternative Names: 2-Ethyl-3,5-dimethyl-pyrazine. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 3,5-Dimethyl-2-ethylpyrazine-d6 (2-Ethyl-3,5-dimethyl-pyrazine-d6) | 3,5-Dimethyl-2-ethylpyrazine-d6 (2-Ethyl-3,5-dimethyl-pyrazine-d6). Group: Biochemicals. Alternative Names: 2-Ethyl-3,5-dimethyl-pyrazine-d6. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| 3-Amino-5,6-dimethyl-pyrazinemethanamine | Heterocyclic Organic Compound. Alternative Names: 2-Pyrazinemethanamine,3-amino-5,6-dimethyl-, 113238-60-1, ACMC-1BV4D, AGN-PC-001QOB, SureCN7329723, CTK4A8163, AG-D-32927, Pyrazinemethanamine, 3-amino-5,6-dimethyl-, Pyrazinemethanamine,3-amino-5,6-dimethyl- (9CI). CAS No. 113238-60-1. Molecular formula: C7H12N4. Mole weight: 152.196980 [g/mol]. Purity: 0.96. IUPACName: 3-(aminomethyl)-5,6-dimethylpyrazin-2-amine. Catalog: ACM113238601. | |
| 3-Amino-6-[4-[[2-(dimethylamino)-1-methylethyl]sulfonyl]phenyl]-N-phenyl-2-pyrazinecarboxamide | Heterocyclic Organic Compound. Alternative Names: 3-amino-6-(4-((1-(dimethylamino)propan-2-yl)sulfonyl)-phenyl)-N-phenylpyrazine-2-carboxamide; 2-Pyridinecarbonitrile,3-amino-6-(3,4-dimethoxyphenyl). CAS No. 1286238-55-8. Molecular formula: C22H25N5O3S. Mole weight: 439.530600 [g/mol]. Purity: 0.96. IUPACName: 3-amino-6-[4-[1-(dimethylamino)propan-2-ylsulfonyl]phenyl]-N-phenylpyrazine-2-carboxamide. Catalog: ACM1286238558. | |
| 5-Bromo-2,3-dimethylpyrazine | Pyrazines. CAS No. 111454-68-3. Molecular formula: C6H7BrN2. Mole weight: 187. Appearance: Colourless Oil. Purity: 0.97. Catalog: ACM111454683. | |
| Dimethyl-2,3 Pyrazine | Dimethyl-2,3 Pyrazine. CAS No. 5910-89-4. FEMA No. 3271. Kosher: Y. VIGON Item # 504547. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| Dimethyl-2,5 Pyrazine | Dimethyl-2,5 Pyrazine. CAS No. 123-32-0. FEMA No. 3272. Kosher: Y. VIGON Item # 500807. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Dimethyl-2,6 Pyrazine | Dimethyl-2,6 Pyrazine. CAS No. 108-50-9. FEMA No. 3273. Kosher: Y. VIGON Item # 504546. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Furo[3,4-b]pyrazine-1(2H)-carboxylic acid, hexahydro-, 1,1-dimethylethyl ester, (4aR,7aS)-rel- | Furo[3,4-b]pyrazine-1(2H)-carboxylic acid, hexahydro-, 1,1-dimethylethyl ester, (4aR,7aS)-rel-. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1314393-75-3. Molecular Formula: C11H20N2O3. Mole Weight: 228.29. Catalog: APB1314393753. |  |
| 2-Chloro-6-[(1Z)-2-ethoxyethenyl]pyrazine | Heterocyclic Organic Compound. Alternative Names: 2-chloro-6,8-dimethyl-quinoline-3-carbaldehyde. CAS No. 1207852-61-6. Molecular formula: C8H9ClN2O. Mole weight: 184.623. Purity: 0.96. IUPACName: 2-Chloro-6-[(Z)-2-ethoxyvinyl]pyrazine. Catalog: ACM1207852616. | |
| Aminoacetaldehyde dimethyl acetal | Aminoacetaldehyde dimethyl acetal (CAS# 22483-09-6) is a versatile building block used for the synthesis of various pharmaceutical compounds. It can be used for the preparation a series of novel pyrazolo[1,5-a]pyrazine derivatives. Synonyms: Ethanamine, 2,2-dimethoxy-; Ethylamine, 2,2-dimethoxy-; 1-Amino-2,2-dimethoxyethane; 1-Amino-2,2-dimethyloxyethane; 2,2-Dimethoxyethan-1-amine; 2,2-Dimethoxyethylamine; 2-Aminoacetaldehyde dimethyl acetal; Aminoacetaldehyde dimethylacetal; DEA; Glycinal dimethyl acetal; N-(2,2-Dimethoxyethyl)amine; NSC 73701. Grades: 95%. CAS No. 22483-09-6. Molecular formula: C4H11NO2. Mole weight: 105.14. | |
| Biapenem Dimer B | Biapenem Dimer B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,2'S,3R,3'R)-2,2'-((2R,3S,7R,8S)-1,6-bis((6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-yl)thio)-2,7-dimethyl-5,10-dioxo-2,3,5,7,8,10-hexahydrodipyrrolo[1,2-a:1',2'-d]pyrazine-3,8-diyl)bis(3-hydroxybutanoate). Molecular Formula: C30H36N8O8S2. Mole Weight: 700.79. Catalog: APB03868. | |
| CCT244747 | CCT244747 is a novel potent, highly selective, orally active ATP-competitive CHK1 inhibitor with potential anticancer activity. CCT244747 inhibited cellular CHK1 activity (IC(50) 29-170 nmol/L), significantly enhanced the cytotoxicity of several anticancer drugs, and abrogated drug-induced S and G(2) arrest in multiple tumor cell lines. CCT244747 represents the first structural disclosure of a highly selective, orally active CHK1 inhibitor and warrants further evaluation alone or combined with genotoxic anticancer therapies. Synonyms: CCT-244747; CCT 244747; 3-{[(2R)-1-(Dimethylamino)-2-propanyl]oxy}-5-{[4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)-2-pyridinyl]amino}-2-pyrazinecarbonitrile; 3-[(1R)-2-(Dimethylamino)-1-methylethoxy]-5-[[4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)-2-pyridinyl]amino]-2-pyrazinecarbonitrile; (R)-3-((1-(dimethylamino)propan-2-yl)oxy)-5-((4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)pyridin-2-yl)amino)pyrazine-2-carbonitrile. Grades: ≥98%. CAS No. 1404095-34-6. Molecular formula: C20H24N8O2. Mole weight: 408.46. | |
| Coenzyme A S-Pyrazinecarboxylate Trisodium Salt | Coenzyme A S-Pyrazinecarboxylate is a derivative of Coenzyme A; a cofactor in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase. Synonyms: S- (2- (3- ( (2R) -4- ( ( ( ( ( ( (2R, 3S, 4R, 5R) -5- (6-Amino-9H-purin-9-yl) -4-hydroxy-3- (phosphonooxy) tetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) oxy) (hydroxy) phosphoryl) oxy) -2-hydroxy-3, 3-dimethylbutanamido) propanamido) ethyl) Pyrazine-2-carbothioate Trisodium Salt. Molecular formula: C26H35N9Na3O17P3S. Mole weight: 939.56. | |
| Deoxybrevianamide e | Deoxybrevianamide E, an indole alkaloid, is a biosynthetic precursor for advanced metabolites isolated from the marine-derived Aspergillus sp. Group: Heterocyclic organic compound. Alternative Names: L-Prolyl-2-(1,1-diMethylallyl)-L-tryptophan anhydride. CAS No. 34610-68-9. Molecular formula: C21H25N3O2. Mole weight: 351.4. Appearance: Oily solid. Purity: 95%+. IUPACName: (3S,8aS)-3-[[2-(2-Methylbut-3-en-2-yl)-1H-indol-3-yl]methyl]-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione. Canonical SMILES: CC (C) (C=C)C1=C (C2=CC=CC=C2N1)CC3C (=O)N4CCCC4C (=O)N3. Catalog: ACM34610689. | |
| Deoxybrevianamide E | An alkaloidal diketopiperazine derived from tryptophan and proline, isolated from aspergillus and penicillium species. Synonyms: L-Prolyl-2-(1,1-dimethylallyl)-L-tryptophan anhydride; (3S,8aS)-3-[[2-(1,1-Dimethyl-2-propen-1-yl)-1H-indol-3-yl]methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione; Prolyl-2- (1, 1-dimethylallyl) tryptophyldiketopiperazine; (3S-trans)-3-[[2-(1,1-Dimethyl-2-propenyl)-1H-indol-3-yl]methyl]hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione; Desoxybrevianamide E; cyclo-2-(1,1-dimethylallyl)-L-tryptophyl-L-proline; cyclo-L-prolyl-2-(1,1-dimethylallyl)-L-tryptophan. Grades: >99% by HPLC. CAS No. 34610-68-9. Molecular formula: C21H25N3O2. Mole weight: 351.44. | |
| Ethyl Isobutyrylacetate | Ethyl Isobutyrylacetate is used in the synthesis of piperazine derivatives as possible multireceptor atypical antipsychotics, affecting dopamine and serotonin receptor properties. Also used in the synthesis of pyrazinecarboxamide DGAT1 (diacylglycerol acyltransferase 1) inhibitors used in the treatment of obesity. Group: Biochemicals. Alternative Names: 3-Oxo-4-methylpentanoic Acid Ethyl Ester; 4-Methyl-3-oxo-pentanoic Acid Ethyl Ester; 4-Methyl-3-oxovaleric Acid Ethyl Ester; Ethyl 2-isobutyrylacetate; Ethyl 3-Isopropyl-3-oxopropanoate; Ethyl 3-oxo-4-methylpentanoate; Ethyl 3-Oxo-4-methylvalerate; Ethyl 4-Methyl-3-oxopentanoate; Ethyl 4-Methyl-3-oxovalerate; Ethyl Isobutyrylacetate; Isobutyrylacetic Acid Ethyl Ester; NSC 62029; γ,γ-Dimethylacetoacetic Acid Ethyl Ester; Ethyl 4-Methyl-3-oxopentanoate. Grades: Highly Purified. CAS No. 7152-15-0. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| JTP 103237 | JTP 103237 is a potent and selective monoacyglycerol acyltransferase 2 (MGAT2) inhibitor (IC50 = 20-40 nM), exhibiting >7000-fold selectivity for human MOGAT2 over human DGAT2. In a high sucrose very low fat (HSVLF) diet induced fatty liver model, JTP-103237 reduced hepatic triglyceride content and hepatic MGAT activity, suppressed not only triglyceride (TG) and diacylglycerol (DG) synthesis, but also fatty acid (FA) synthesis (de novo lipogenesis). Synonyms: 7-[4,6-Bis(1,1-dimethylethyl)-2-pyrimidinyl]-5,6,7,8-tetrahydro-3-[4-(trifluoromethoxy)phenyl]-1,2,4-triazolo[4,3-a]pyrazine. Grades: ≥98% by HPLC. CAS No. 1883864-16-1. Molecular formula: C24H29F3N6O. Mole weight: 474.52. | |
| Methyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl] Propionate | An derivative of Pyrazine.Pyrazine is a heterocyclic aromatic organic compound. Synonyms: Dimethyl 3,3'-(pyrazine-2,5-diyl)dipropanoate; 77479-01-7; methyl 3-[5-(3-methoxy-3-oxopropyl)pyrazin-2-yl]propanoate; Methyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl]propionate; DTXSID10345691; CAVDNRICPLKYEH-UHFFFAOYSA-N; AKOS015999873; Propanoic acid, 3-[5-(3-methoxy-3-oxopropyl)-2-pyrazinyl]-, methyl ester; AM806624; 2,5-Pyrazinedipropanoic Acid Dimethyl Ester; CS-0455630; Dimethyl3,3'-(pyrazine-2,5-diyl)dipropanoate; Dimethyl 3,3'-(pyrazine-2,5-diyl)dipropionate; A865224. Grades: > 95%. CAS No. 77479-01-7. Molecular formula: C12H16N2O4. Mole weight: 252.27. | |
| N-(5-Nitropyridin-2-yl)acetamide | Heterocyclic Organic Compound. Alternative Names: FEMA NUMBER 3272; 2,4-DIMETHOXYTOLUENE; 2,5-Dimethyl; 2,5-dimethyl-pyrazin; 2,5-Dimethylprazin; 5-diMethyl pyrazine; FEMA 3272; KETINE; GLYCOLINE; 2,5-Dimethylpiazine; 2,5-Dimethylpyrazine. CAS No. 123-32-412. Molecular formula: C7H7N3O3. Mole weight: 181.1488. Appearance: clear colorless to pale yellow liquid. Purity: 0.96. IUPACName: 2,5-Dimethyl pyrazine. Density: 0.99. Catalog: ACM12332412. | |
| Octahydro-2H-pyrazino[1,2-a]pyrazine-2-carboxylic acid tert-butyl ester | Octahydro-2H-pyrazino[1,2-a]pyrazine-2-carboxylic acid tert-butyl ester. Group: Biochemicals. Alternative Names: Octahydro-2H-pyrazino[1,2-a]pyrazine-2-carboxylic acid 1,1-dimethylethyl ester. Grades: Highly Purified. CAS No. 1159825-34-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C12H23N3O2. US Biological Life Sciences. | Worldwide |
| TC-E 5005 | TC-E 5005 is a potent and selective PDE10A inhibitor (IC50 = 7.28, 239, 779, 919, 3100 and 3700 nM at PDE10A, 2A, 11A, 5A, 7B and 3A respectively, and >5000 nM at PDE1B, 4A, 6, 8A and 9A). TC-E 5005 reverses MK 801-induced hyperactivity and stereotypy in vivo. It also inhibits adrenergic and neurogenic smooth muscle contractions in the human prostate. Synonyms: TC-E 5005; TC E-5005; TC E 5005; TC-E-5005; TCE5005; 2-Methoxy-6,7-dimethyl-9-propyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine. Grades: ≥99% by HPLC. CAS No. 959705-64-7. Molecular formula: C15H18N4O. Mole weight: 270.33. | |
| tert-Butyl 3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate | tert-Butyl 3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: 5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-carboxylic Acid 1,1-Dimethylethyl Ester; 7-tert-Butoxycarbonyl-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine. CAS No. 877402-43-2. Molecular formula: C11H15F3N4O2. Mole weight: 292.26. | |
| tert-Butyl 6-formyl-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-2-carboxylate | Heterocyclic Organic Compound. Alternative Names: 1174068-79-1, tert-Butyl 6-formyl-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate, tert-Butyl 6-formyl-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-2-carboxylate, CTK8B7039, ANW-56216, AKOS015949359, PB26915, RP07677, AK-30871, KB-260833, FT-0684664, Y7169, tert-butyl 6-formyl-1H,3H,4H-pyrrolo[1,2-a]pyrazine-2-carboxylate, PYRROLO[1,2-A]PYRAZINE-2(1H)-CARBOXYLIC ACID, 6-FORMYL-3,4-DIHYDRO-, 1,1-DIMETHYLETHYL ESTER. CAS No. 1174068-79-1. Molecular formula: C13H18N2O3. Mole weight: 250.296. Purity: 0.96. IUPACName: tert-butyl 6-formyl-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-2-carboxylate. Canonical SMILES: CC(C)(C)OC(=O)N1CCN2C(=CC=C2C=O)C1. Catalog: ACM1174068791. | |
| tert-Butyl 8-Oxo-3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate | tert-Butyl 8-Oxo-3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: 5,6-Dihydro-8-oxo-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-carboxylic Acid 1,1-Dimethylethyl Ester. CAS No. 877402-44-3. Molecular formula: C11H13F3N4O3. Mole weight: 306.24. | |
| 1,5,6-Trimethyl-1,2-dihydro-3H-pyrazolo[3,4-b]pyrazin-3-one | Heterocyclic Organic Compound. Alternative Names: 101554-46-5, (6R,7S)-6,7-DIMETHYL-6,7-DIHYDROPTERIDIN-4(1H)-ONE, ACMC-20m4lj, 4(1H)-Pteridinone,6,7-dihydro-6,7-dimethyl-, (6R-cis)- (9CI). CAS No. 101554-46-5. Molecular formula: C8H10N4O. Mole weight: 178.191200 [g/mol]. Purity: 0.96. IUPACName: 6,7-dimethyl-6,7-dihydro-1H-pteridin-4-one. Catalog: ACM101554465. | |
| 1-(7-Bromo-4-methyl-3,4-dihydropyrido[2,3-b]-pyrazin-1(2h)-yl)-2,2-dimethylpropan-1-one | 1-(7-Bromo-4-methyl-3,4-dihydropyrido[2,3-b]-pyrazin-1(2h)-yl)-2,2-dimethylpropan-1-one. Group: Biochemicals. Grades: Highly Purified. CAS No. 1142192-65-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C13H18BrN3O, Molecular Weight: 312.209999999999. US Biological Life Sciences. | Worldwide |
| 2-Amino-1-(3-((4-chlorophenyl)amino)-2-(4-fluorophenyl)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)ethanone | 2-Amino-1-(3-((4-chlorophenyl)amino)-2-(4-fluorophenyl)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)ethanone also known as GNF 179 is used in the imaging of plasmodium parasites for next generation antimalarial drug discovery. Group: Biochemicals. Grades: Highly Purified. CAS No. 1261114-01-5. Pack Sizes: 5mg, 10mg. Molecular Formula: C22H23ClFN5O, Molecular Weight: 427.9. US Biological Life Sciences. | Worldwide |
| (2S) -2-Cyclohexyl-N- (2-pyrazinylcarbonyl) glycyl-3-methyl-L-valine | (2S) -2-Cyclohexyl-N- (2-pyrazinylcarbonyl) glycyl-3-methyl-L-valine. Group: Biochemicals. Alternative Names: (2S) -2-Cyclohexyl-N- (pyrazinylcarbonyl) glycyl-3-methyl-L-valine; (S) -2-[ (S) -2-Cyclohexyl-2-[ (pyrazinyl-2-carbonyl) amino]acetylamino]-3, 3-dimethylbutyric acid. Grades: Highly Purified. CAS No. 402958-96-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C19H28N4O4. US Biological Life Sciences. | Worldwide |
| 3,5-Dimethylpyrazinol | 3,5-Dimethylpyrazinol. Group: Biochemicals. Alternative Names: 3,5-Dimethyl-2(1H)-pyrazinone. Grades: Highly Purified. CAS No. 60187-00-0. Pack Sizes: 250mg. Molecular Formula: C6H8N2O, Molecular Weight: 124.14. US Biological Life Sciences. | Worldwide |
| 3-(Dimethylamino)-1-(2-pyrazinyl)-2-propen-1-one | Heterocyclic Organic Compound. Alternative Names: (2E)-3-(dimethylamino)-1-(pyrazin-2-yl)prop-2-en-1-one, 111781-53-4, 3-(Dimethylamino)-1-(pyrazin-2-yl)prop-2-en-1-one, AC1NYBEK, AC1Q3VVG, SureCN4262480, dimethylaminopyrazinylpropenone, MolPort-002-867-061, MolPort-019-747-074, SBB089275, ZINC06176740, AKOS005070361, PB17286, RP10768, AK-56054, FT-0680329, 3-DIMETHYLAMINO-1-PYRAZIN-2-YL-PROPENONE, 3W-0873, I05-1907, (2E)-3-(dimethylamino)-1-pyrazin-2-ylprop-2-en-1-one. CAS No. 111781-53-4. Molecular formula: C9H11N3O. Mole weight: 177.21. Purity: 0.96. IUPACName: (E)-3-(dimethylamino)-1-pyrazin-2-ylprop-2-en-1-one. Canonical SMILES: CN(C)C=CC(=O)C1=NC=CN=C1. Catalog: ACM111781534. | |
| 3-Isobutyl-1-methyl-d3-2-pyrazinone | Heterocyclic Organic Compound. CAS No. 1219805-28-3. Molecular formula: 169.24. Mole weight: 401.454503;g/mol. Purity: 99 atom % D. IUPACName: ethyl5-[2-[1-(3-fluorophenyl)imidazol-2-yl]sulfanylacetyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate. Canonical SMILES: CCOC (=O)C1=C (NC (=C1C)C (=O)CSC2=NC=CN2C3=CC (=CC=C3)F)C. Catalog: ACM1219805283. | |
| 3-(Pyrazin-2-yl)benzoic acid | 3-(Pyrazin-2-yl)benzoic acid. Group: Carboxylic acid nitrogen-containing mixed mof ligand-binary mixed ligand. Alternative Names: Benzoic acid, 3-Pyrazinyl-; 3-(3,6-Dimethylpyrazin-2-yl)benzoic acid. CAS No. 856905-13-0. Product ID: 3-pyrazin-2-ylbenzoic acid. Molecular formula: 200.19. Mole weight: C11H8N2O2. InChI=1S/C11H8N2O2/c14-11 (15)9-3-1-2-8 (6-9)10-7-12-4-5-13-10/h1-7H, (H, 14, 15). FQEYELBTYMODMC-UHFFFAOYSA-N. 95%+. |  |
| Brevicompanine B | A diketopiperazine-related metabolite produced by penicillium brevicompactum and aspergillus species. It has obvious plant growth regulation activity, but is devoid of antifungal or antimicrobial activity. It is active against Plasmodium falciparum. Synonyms: (3R,5aS,10bR,11aS)-10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione. Grades: >99% by HPLC. CAS No. 215121-47-4. Molecular formula: C22H29N3O2. Mole weight: 367.48. | |
| CCT196969 | This active molecular is a novel , paradox-breaking pan-RAF inhibitor with anti-SRC activity and it blocked growth of BRAF-mutant and NRAS-mutant melanoma cells, inhibiting MEK -ERK. CCT196969 also prevented growth of xenografts derived from patient tumours with resistance to BRAF and MEK inhibitors. Uses: Effective in drug-resistant braf mutant melanoma. Synonyms: CCT196969; CCT-196969; CCT 196969. N-[4-[(3,4-Dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-fluorophenyl]-N'-[3-(1,1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]urea. Grades: 98%. CAS No. 1163719-56-9. Molecular formula: C27H24FN7O3. Mole weight: 513.52. | |
| CCT239065 | CCT239065 is a mutant protein kinase inhibitor that inhibits signaling downstream of V600EBRAF in cancer cells, blocking DNA synthesis, and inhibiting proliferation. Group: Biochemicals. Alternative Names: N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-(methylthio)phenyl]-N'-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-urea. Grades: Highly Purified. CAS No. 1163719-51-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Chaetocin | It is produced by the strain of Chaetomium minutum. It has the activity of anti-gram-positive bacteria and negative bacteria. Synonyms: Caetocin; Chetocin; 3,11a-Epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole, bimol. deriv.; (+)-Chaetocin; (+)-Chaetocin A; Chaetocin A; [3S-[3α, 5aβ, 10bβ(3'R*, 5'aS*, 10'bS*, 11'aR*), 11aα]]-2, 2', 3, 3', 5a, 5'a, 6, 6'-Octahydro-3, 3'-bis(hydroxymethyl)-2, 2'-dimethyl-[10b, 10'b(11H, 11'H)-Bi-3, 11a-epidithio-11aH-pyrazino[1', 2':1, 5]pyrrolo[2, 3-b]indole]-1, 1', 4, 4'-tetrone; NSC-745363. Grades: >99% by HPLC. CAS No. 28097-03-2. Molecular formula: C30H28N6O6S4. Mole weight: 696.84. | |
| Chetomin | It is produced by the strain of Chaetomium cochloides , Ch.globosum, Ch.fuunienlum, Ch.elatun, Ch.spirale and Verticillium cinnabarium. Chetomin is a natural metabolite produced by several species of the genus chaetomium. It is an epidithiodioxopiperazine and is an inhibitor of hypoxia-inducible factor (HIF). It inhibits interaction of HIF1α and HIF2α with transcriptional co-activators p300 and cAMP response element binding (CREB) protein (CBP). It decreases tumor growth by attenuating hypoxia-inducible transcription and disrupting the ability of tumors to adapt to hypoxia. It also suppresses the proliferation of LPS-induced mouse spleen lymphocytes. It may be used as an antibacterial agent and is used in antitumor research. It also may be useful in radiotherapeutic. Synonyms: CTM; NSC-289491; NSC 289491; NSC289491; Chaetomin; (3S,5aR,10bS,11aS)-2,3,5a,6,10b,11-Hexahydro-3-(hydroxymethyl)-10b-[(1S,4S)-3-[[4-(hydroxymethyl)-5,7-dimethyl-6,8-dioxo-2,3-dithia-5,7-diazabicyclo[2.2.2]oct-1-yl]methyl]-1H-indol-1-yl]-2-methyl-3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione. Grades: ≥98% by HPLC. CAS No. 1403-36-7. Molecular formula: C31H30N6O6S4. Mole weight: 710.87. | |
| Des [N- [ (1S) -1- [2- (cyclopropylamino) -2-oxoacetyl] butyl] carboxamido] 1-tert-Butyloxycarbonyl Telaprevir | Intermediate in the preparation of Telaprevir. Group: Biochemicals. Alternative Names: (1S, 3aR, 6aS) -2-[ (2S) -2-[[ (2S) -2-Cyclohexyl-2-[ (2-pyrazinylcarbonyl) amino]acetyl]amino]-3, 3-dimethyl-1-oxobutyl]octahydro-cyclopenta[c]pyrrole-1-carboxylic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 926276-19-9. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| GDC-0853 | GDC-0853 is a Bruton's tyrosine kinase (BTK) inhibitor originated by Genentech. GDC-0853 can inhibit the activity of BTK and prevent the activation of the B-cell antigen receptor (BCR) signaling pathway. This leads to the inhibition of the growth of malignant B-cells that overexpress BTK. Phase III clinical trials for the treatment of Multiple sclerosis and Phase II clinical trials for the treatment of Chronic urticaria and Systemic lupus erythematosus are on-going. Uses: Rheumatoid arthritis; autoimmune disorders. Synonyms: Fenebrutinib; RG 7845; RG7845; GDC0853; RG-7845; GDC 0853; (S)-2-(3'-(hydroxymethyl)-1-methyl-5-((5-(2-methyl-4-(oxetan-3-yl)piperazin-1-yl)pyridin-2-yl)amino)-6-oxo-1,6-dihydro-[3,4'-bipyridin]-2'-yl)-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one. Grades: 98%. CAS No. 1434048-34-6. Molecular formula: C37H44N8O4. Mole weight: 664.81. | |
| Gypsetin | It is produced by the strain of Nannizzia gypsea var. incurvata IFO 9228. It can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with IC50 of 18 μmol/L, and its action is competitive with oleoyl-COA substrate, Ki value is 5.5 μmol/L. It also inhibits [14C] oleic acid from forming cholesterol esters with IC50 of 0.65 μmol/L. Synonyms: Gypsetine; (-)-Gypsetin; 8a, 16a-Dihydroxy-5a, 13a-bis (1, 1-dimethylallyl)- (1)-benzazolidine- (3''', 2''': 4'', 5'')azolidino- (1'', 2'': 4', 5') (1, 4)perhydrodiazin- (1', 2': 1, 5)azolidino- (2, 3-b)- (1)-benzazolidine-7, 15-dione; Pyrazino(1'', 2'':1, 5;4'', 5'':1', 5')dipyrrolo(2, 3-b:2', 3'-b')diindole-7, 15(5H, 7aH)-dione, 5a, 13a-bis(1, 1-dimethyl-2-propenyl)-5a, 8, 8a, 13, 13a, 15a, 16, 16a-octahydro-8a, 16a-dihydroxy-, (5aalpha, 7aalpha, 8abeta, 13abeta, 15aalpha, 16aalpha)-. CAS No. 155114-38-8. Molecular formula: C32H36N4O4. Mole weight: 540.66. | |
| JJH260 | JJH260 is an inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). JJH260 was shown to found members of an evolutionarily conserved class of transmembrane threonine hydrolases involved in bioactive lipid metabolism. Synonyms: 7-(4-(dimethylamino)benzoyl)-1,3-dioxohexahydroimidazo[1,5-a]pyrazin-2(3H)-yl 4-(4-chlorophenethyl)piperidine-1-carboxylate. Grades: ≥90%. CAS No. 1831135-30-8. Molecular formula: C29H34ClN5O5. Mole weight: 568.1. | |
| Leptosin I | It is produced by the strain of I Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.13 μg/mL. Synonyms: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (5alpha,6S,6'S,15alpha)-; (+)-Leptosin I; 22bH-18, 22a-(Iminomethano)-10b, 23a-methano-10bH, 23aH-indolo[2'', 3'':2', 3'][1, 2, 3, 4, 6]tetrathiazocino[6'', 5'':1', 5']pyrrolo[3', 4':6, 7]pyrazino[2''', 1''':2, 3][1, 3]oxazepino[4, 5-b]indole-1, 4, 17, 25(18H)-tetrone, 2, 3, 5a, 6, 15, 15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2, 26-dimethyl-18-(1-methylethyl)-, (3a, 5ab, 10ba, 10cS*, 15ab, 18b, 22ab, 22ba, 23aa, 24S*)-(+)-; Leptosine I. CAS No. 160472-96-8. Molecular formula: C32H32N6O7S4. Mole weight: 740.89. | |
| Leptosin J | It is produced by the strain of J Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.25 μg/mL. Synonyms: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (2alpha,5alpha,6S,6'S,15alpha)-; 22bH-18, 22a-(Iminomethano)-10b, 23a-methano-10bH, 23aH-indolo[2'', 3'':2', 3'][1, 2, 3, 4, 6]tetrathiazocino[6'', 5'':1', 5']pyrrolo[3', 4':6, 7]pyrazino[2''', 1''':2, 3][1, 3]oxazepino[4, 5-b]indole-1, 4, 17, 25(18H)-tetrone, 2, 3, 5a, 6, 15, 15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2, 26-dimethyl-18-(1-methylethyl)-, (3a, 5aa, 10bb, 10cR*, 15aa, 18a, 22aa, 22bb, 23ab, 24R*)-(+)-; Leptosine J. CAS No. 160550-15-2. Molecular formula: C32H32N6O7S4. Mole weight: 740.89. | |
| LEQ-506 | an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Uses: Solid tumors. Synonyms: (R)-2-(5-(4-(6-benzyl-4,5-dimethylpyridazin-3-yl)-2-methylpiperazin-1-yl)pyrazin-2-yl)propan-2-ol. Grades: > 95%. CAS No. 1204975-42-7. Molecular formula: C25H32N6O. Mole weight: 432.57. | |
| LGK974 | LGK974 is a selective and orally bioavailable Porcupine inhibitor under development for the treatment of cancers that are driven by the Wnt pathway in a Wnt ligand-dependent manner. LGK974 was shown to induce tumor regression in a Wnt-driven murine tumor model. Synonyms: LGK-974; WNT-974; 2-(2',3-Dimethyl-[2,4'-bipyridin]-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide; 2-[5-methyl-6-(2-methylpyridin-4-yl)pyridin-3-yl]-N-(5-pyrazin-2-ylpyridin-2-yl)acetamide. Grades: >98%. CAS No. 1243244-14-5. Molecular formula: C23H20N6O. Mole weight: 396.454. | |
| LGK974 (LGK-974, WNT-974, LGK 974, NVP-LGK974) | LGK974 is a highly potent inhibitor of Porcupine (PORCN), a Wnt-specific acyltransferase. LGK974 is orally bioavailable and inhibits WNT signaling in vitro and in vivo. It is reported to exhibit anti-tumor properties without increasing cytotoxicity. Group: Biochemicals. Alternative Names: 2-[5-methyl-6-(2-methylpyridin-4-yl)pyridin-3-yl]-N-(5-pyrazin-2-ylpyridin-2-yl)acetamide; LGK-974; WNT-974; LGK 974; NVP-LGK974; 2,3-Dimethyl-N-[5-(2-pyrazinyl)-2-pyridinyl]-[2,4-bipyridine]-5-acetamide; 2-(2,3-Dimethyl-[2,4-bipyridin]-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide. Grades: Highly Purified. CAS No. 1243244-14-5. Pack Sizes: 1mg, 5mg, 25mg, 100mg. Molecular Formula: C??H??N?O, Molecular Weight: 396.44. US Biological Life Sciences. | Worldwide |
| LIMK1 inhibitor BMS 4 | LIMK1 inhibitor BMS 4 is a potent LIM kinase 1 (LIMK1; IC50 = 22nM) inhibitor devoid of any cytotoxic side effects. Synonyms: 1-ethyl-3-[5-[6-(4-methoxy-2,6-dimethylphenyl)-2-pyrazin-2-ylpyrimidin-4-yl]-1,3-thiazol-2-yl]urea. Grades: 99%. CAS No. 905298-84-2. Molecular formula: C23H23N7O2S. Mole weight: 461.54. | |
| Nα-Boc-Nδ-pyrazinylcarbonyl-L-ornithine | Synonyms: Boc-L-Orn(pyrazinylcarbonyl)-OH; L-Ornithine, N2-[(1,1-dimethylethoxy)carbonyl]-N5-(pyrazinylcarbonyl)-(9CI). Grades: ≥ 99% (HPLC). CAS No. 201046-36-8. Molecular formula: C15H22N4O5. Mole weight: 338.36. | |
| N-Boc-N-desmethyl Zopiclone | Zopiclone intermediate. Group: Biochemicals. Alternative Names: 1-tert-Butyl 4-[6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl]piperazine-1,4-dicarboxylate; 1,4-Piperazinedicarboxylic Acid 1-[6-(5-Chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl] 4-(1,1-Dimethylethyl) Ester. Grades: Highly Purified. CAS No. 1076199-62-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| N-Boc-N-desmethyl Zopiclone-d8 | Labeled Zopiclone intermediate. Group: Biochemicals. Alternative Names: 1-tert-Butyl 4-[6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl]piperazine-1,4-dicarboxylate-d8; 1,4-Piperazinedicarboxylic Acid 1-[6-(5-Chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl] 4-(1,1-Dimethylethyl) Ester-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Pyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid,6-(6-benzofuranyl)-1,2,3,4,6,7,12,12a-octahydro-1,4-dioxo-,1,1-dimethylethyl ester,(3s,6r,1 | Heterocyclic Organic Compound. CAS No. 1053613-80-1. Molecular formula: C29H29N3O5. Mole weight: 499.55766;g/mol. Purity: 0.96. Canonical SMILES: CC (C) (C)OC (=O)CCC1C (=O)N2C (CC3=C (C2C4=CC5=C (C=C4)C=CO5)NC6=CC=CC=C36)C (=O)N1. Catalog: ACM1053613801. | |
| Roquefortine C | A potent tremorgenic mycotoxin originally isolated from penicillium roqueforti. It is a penicillium commercially used to ripen blue-veined cheese. Synonyms: Roquefortine; NSC 292134; (3E,5aS,10bR,11aS)-10b-(1,1-Dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(1H-imidazol-5-ylmethylene)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione; (-)-Roquefortine C; Roquefortin. Grades: >99% by HPLC. CAS No. 58735-64-1. Molecular formula: C22H23N5O2. Mole weight: 389.45. | |
| (R)-Telaprevir | (R)-Telaprevir is an enantiomer of Telaprevir , an inhibitor of the hepatitis C virus NS3-4A protease. Group: Biochemicals. Alternative Names: (1S, 3aR, 6aS) -2- [ (2S) -2- [ [ (2S) -2-cyclohexyl-2- [ (2-pyrazinylcarbonyl) amino] acetyl] amino] -3, 3-dimethyl-1-oxobutyl] -N- [ (1R) -1- [2- (cyclopropylamino) -2-oxoacetyl] butyl] octahydrocyclopenta [c] pyrrole-1-carboxamide. Grades: Purified. CAS No. 923270-50-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Sitagliptin Impurity 18 | Sitagliptin Impurity 18 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin N-Boc Impurity; (R)-tert-Butyl (4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate; N-[ (1R) -3-[5, 6-Dihydro-3- (trifluoromethyl) -1, 2, 4-triazolo[4, 3-a]pyrazin-7 (8H) -yl]-3-oxo-1-[ (2, 4, 5-trifluorophenyl) methyl]propyl]carbamic Acid 1,1-Dimethylethyl Ester. Grades: >95%. CAS No. 486460-23-5. Molecular formula: C21H23F6N5O3. Mole weight: 507.43. | |
| UMB-32 | UMB-32 is an inhibitor of the BET bromodomain BRD4 (Kd = 550 nM; IC50 = 637 nM) and the bromodomain-containing transcription factor TAF1 (Kd = 560 nM) and TAF1L (Kd = 1.3 μM). Synonyms: N-Tert-Butyl-2-[4-(3,5-Dimethyl-1,2-Oxazol-4-Yl)phenyl]imidazo[1,2-A]pyrazin-3-Amine. Grades: ≥98%. CAS No. 1635437-39-6. Molecular formula: C21H23N5O. Mole weight: 361.4. | |
| Varioxepine A | Varioxepine A is a fungal metabolite produced by the strain of P. variotii. It is active against the plant pathogenic fungus F. graminearum (MIC = 4 μg/ml). Synonyms: Varioxepine A; 1623451-72-8; (16aR)3R,4-dihydro-4,4-dimethyl-10-(1-methylethyl)-7S-(phenylmethyl)-3,5aS-epoxy-2H,5aH,7H-[1,4]dioxepino[2,3-e]oxepino[2,3-d]pyrazino[1,2-a]pyrimidin-8(9H)-one; (1S, 3S, 15R, 18R)-3-benzyl-19, 19-dimethyl-6-propan-2-yl-10, 16, 20, 21-tetraoxa-2, 5, 8-triazapentacyclo[16.2.1.01, 15.02, 7.09, 15]henicosa-6, 8, 11, 13-tetraen-4-one; HY-N10256; CS-0371780. Grades: >95% by HPLC. CAS No. 1623451-72-8. Molecular formula: C26H29N3O5. Mole weight: 463.52. | |
| Verrucofortine | A diketopiperazine alkaloid derived from tryptophan and leucine. It is a fungal metabolite isolated from penicillium verrucosum. It exhibits no apparent toxicity in mice even at high doses in vivo. Synonyms: Fructigenine B; Verrucosine; Verrucozine; (-)-Verrucofortine; (3S-(3alpha,5aalpha,10balpha,11abeta))-6-Acetyl-10b-(1,1-dimethyl-2-propenyl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino(1',2':1,5)pyrrolo(2,3-b)indole-1,4-(3H,5aH)-dione; (3S,5aR,10bR,11aS)-6-acetyl-10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione. Grades: >99% by HPLC. CAS No. 113706-21-1. Molecular formula: C24H31N3O3. Mole weight: 409.52. | |
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