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| Product | Description | |
|---|---|---|
| Elvitegravir | A novel inhibitor of human immunodeficiency virus type 1 integrase. Group: Biochemicals. Alternative Names: 6-[(3-Chloro-2-fluorophenyl)methyl]-1,4-dihydro-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-3-quinolinecarboxylic Acid; GS 9137; JTK 303. Grades: Highly Purified. CAS No. 697761-98-1. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Elvitegravir | Elvitegravir (GS-9137; JTK-303; D06677) is an HIV integrase inhibitor for HIV-1 IIIB , HIV-2 EHO and HIV-2 ROD with IC 50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9137; JTK-303; D06677. CAS No. 697761-98-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14740. |  |
| Elvitegravir | Elvitegravir is an HIV-1 integrase strand transfer inhibitor (INSTI) for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively. Uses: Anti-retroviral agents. Synonyms: GS-9137; GS 9137; GS9137; JTK-303; JTK 303; JTK303; EVG; D06677; D 06677; D-06677. Grades: ≥98%. CAS No. 697761-98-1. Molecular formula: C23H23ClFNO5. Mole weight: 447.88. |  |
| Elvitegravir, 7-Desmethoxy-7-fluoro | Elvitegravir derivative. Group: Biochemicals. Alternative Names: 6-(3-Chloro-2-fluorobenzyl)-7-fluoro-1-[(S)-1-hydroxymethyl-2-methylpropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; 6-[(3-Chloro-2-fluorophenyl)methyl]-7-fluoro-1,4-dihydro-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-4-oxo-3-quinolinecarboxylic Acid. Grades: Highly Purified. CAS No. 869893-92-5. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Elvitegravir-d6 (Major) | A novel labeled inhibitor of human immunodeficiency virus type 1 integrase. Group: Biochemicals. Alternative Names: 6-[(3-Chloro-2-fluorophenyl)methyl]-1,4-dihydro-1-[(1S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-3-quinolinecarboxylic Acid. Grades: Highly Purified. CAS No. 1131640-69-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-Chloro-3-fluoro Elvitegravir | 2-Chloro-3-fluoro Elvitegravir is an impurity of Elvitegravir (E509000), which is a novel inhibitor of human immunodeficiency virus type 1 integrase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C23H23ClFNO5, Molecular Weight: 447.88. US Biological Life Sciences. | Worldwide |
| para-Hydroxy Elvitegravir (Elvitegravir M1) | Synonyms: p-Hydroxy elvitegravir; Elvitegravir (m1); 870648-10-5; UNII-7H5PG477IY; 7H5PG477IY; para-Hydroxy Elvitegravir (Elvitegravir M1); 3-Quinolinecarboxylic acid, 6-((3-chloro-2-fluoro-4-hydroxyphenyl)methyl)-1,4-dihydro-1-((1S)-1-(hydroxymethyl)-2-methylpropyl)-7-methoxy-4-oxo-; 6-[(3-chloro-2-fluoro-4-hydroxyphenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxoquinoline-3-carboxylic acid; SCHEMBL4360750; DTXSID50870376; Q27268282. Grades: > 95%. CAS No. 870648-10-5. Molecular formula: C23H23ClFNO6. Mole weight: 463.89. | |
| D-Valinol | D-Valinol (CAS# 4276-09-9) is used as a reagent in the synthesis of the HIV type 1 integrase inhibitor Elvitegravir (E509000). D-Valinol is also used in the preparation of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer's disease. Synonyms: H-D-Val-ol; (R)-(-)-2-Amino-3-methyl-1-butanol. Grades: ≥ 99 % (GC). CAS No. 4276-9-9. Molecular formula: C5H13NO. Mole weight: 103.2. | |
| GS-7340 fumarate | Tenofovir alafenamide fumarate, also known as Tenofovir alafenamide hemifumarate; TAF, GS-7340, is a nucleotide reverse transcriptase inhibitor and a novel prodrug of tenofovir. It is under development by Gilead Sciences for use in the treatment of HIV infection. Closely related to the commonly used reverse-transcriptase inhibitor tenofovir disoproxil fumarate (Viread), Tenofovir alafenamide has greater antiviral activity and better distribution into lymphoid tissues than that agent. Gilead has announced a phase 3 clinical trial evaluating a single-tablet regimen combining GS-7340 with cobicistat, emtricitabine and elvitegravir and plans to coformulate the drug with cobicistat, emtricitabine and the protease inhibitor darunavir. In a 48 week study comparing Elvitegravir / cobicistat / emtricitabine / tenofovir disoproxil fumarate to elvitegravir / cobicistat / emtricitabine / tenofovir alafenamide fumarate, the results showed the prodrug to be non inferior to the established agent, but at much lower dosages and with lower incidence of adverse side effects such as impaired kidney function. Synonyms: GS-7340 fumarate; GS 7340 fumarate; GS7340 fumarate; (S)-isopropyl 2- ( ( (S)- ( ( ( (R)-1- (6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) (phenoxy)phosphoryl)amino)propanoate fumarate; TAF; GS734; GS-734; GS 7340; Tenofovir alafenamide fumarate; trade name: Genvoya. Grades: >98%. CAS No. 379270-38-9. Molecular formula: C25H33N6O9P. Mole weight: 592.54. | |
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