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| Product | Description | |
|---|---|---|
| Fibrinogen Binding Inhibitor Peptide | Fibrinogen Binding Inhibitor Peptide is a dodecapeptide (HHLGGAKQAGDV, H12), which is a fibrinogen γ-chain carboxy-terminal sequence (γ400-411). Fibrinogen Binding Inhibitor Peptide is a specific binding site of the ligand for activated glycoprotein (GP) IIb/IIIa. Uses: Scientific research. Group: Peptides. CAS No. 89105-94-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1507. |  |
| Fibrinogen Binding Inhibitor Peptide | Fibrinogen Binding Inhibitor Peptide is an effective inhibitor of the binding of fibrinogen, fibronectin and von Willebrand factor to thrombin- or ADP-stimulated platelets. It is also a synthetic dodecapeptide that represents the specific platelet receptor recognition site for the human fibrinogen G-chain (residues 400-411). Synonyms: H-His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val-OH; L-histidyl-L-histidyl-L-leucyl-glycyl-glycyl-L-alanyl-L-lysyl-L-glutaminyl-L-alanyl-glycyl-L-alpha-aspartyl-L-valine; fibrinogen-γ fragment 400-411. Grades: ≥95%. CAS No. 89105-94-2. Molecular formula: C50H80N18O16. Mole weight: 1189.28. |  |
| Fibrinogen-Binding Peptide | Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin [1]. Uses: Scientific research. Group: Peptides. CAS No. 137235-80-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1741. | |
| Fibrinogen-Binding Peptide | Fibrinogen-Binding Peptide (designed by the anti-complementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. It binds to fibrinogen and inhibits platelet adhesion to fibrinogen and platelet aggregation, as well as platelet adhesion to hyalonectin. Synonyms: H-EHIPA-OH; L-alpha-glutamyl-L-histidyl-L-isoleucyl-L-prolyl-L-alanine; N-(1-(N-(N-L-alpha-glutamyl-L-histidyl)-L-isoleucyl)-L-prolyl)-L-Alanine; EHIPA. Grades: ≥95%. CAS No. 137235-80-4. Molecular formula: C25H39N7O8. Mole weight: 565.62. | |
| Fibrinogen-Binding Peptide butyl acetate | Fibrinogen-Binding Peptide (designed by the anti-complementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. It binds to fibrinogen and inhibits platelet adhesion to fibrinogen and platelet aggregation, as well as platelet adhesion to vitronectin. Synonyms: Fibrinogen-Binding Peptide (fb-acetate); H-Glu-His-Ile-Pro-Ala-OH butyl acetate; EHIPA butyl acetate; L-alpha-glutamyl-L-histidyl-L-isoleucyl-L-prolyl-L-alanine butyl acetate. Grades: ≥95%. Molecular formula: C31H51N7O10. Mole weight: 681.80. | |
| Fibrinogen (Bovine) | Fibrinogen (Bovine) is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9001-32-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-125864. | |
| 1-[1, 1-Dimethylethoxy) ?carbonyl]?-?4-piperidinepropanoic Acid Methyl Ester | 1-[1, 1-Dimethylethoxy) ?carbonyl]?-?4-piperidinepropanoic Acid Methyl Ester is used to prepare arginylglycylaspartic acid derivatives as fibrinogen receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 162504-75-8. Pack Sizes: 100mg, 500 mg. Molecular Formula: C14H25NO4, Molecular Weight: 271.35. US Biological Life Sciences. |  Worldwide |
| Arg-Gly-Asp-Cys acetate | Arg-Gly-Asp-Cys, a fibronectin binding motif to cell adhesion molecules, inhibits platelet aggregation and fibrinogen binding. Synonyms: L-arginyl-glycyl-L-alpha-aspartyl-L-cysteine; RGDC peptide. Molecular formula: C17H31N7O9S. Mole weight: 509.54. | |
| Arg-Gly-Asp-Ser | Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. It inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor. It promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. It also blocks the attachment of certain pathogens to cells. Uses: Platelet aggregation inhibitors. Synonyms: Arg Gly Asp Ser; RGDS peptide; Fibronectin Inhibitor. Grades: >98%. CAS No. 91037-65-9. Molecular formula: C15H27N7O8. Mole weight: 433.42. | |
| Arg-Gly-Asp-Ser acetate | Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. It inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor. It promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. It also blocks the attachment of certain pathogens to cells. Molecular formula: C17H31N7O10. Mole weight: 493.47. | |
| Arg-Gly-Glu-Ser | Arg-Gly-Glu-Ser, a RGD-related peptide, is a control for the RGDS ihibitory activity on fibrinogen binding to activated platelets. Synonyms: H-Arg-Gly-Glu-Ser-OH; L-arginyl-glycyl-L-alpha-glutamyl-L-serine; (4S) -4-[[2-[[ (2S) -2-amino-5- (diaminomethylideneamino) pentanoyl]amino]acetyl]amino]-5-[[ (1S) -1-carboxy-2-hydroxyethyl]amino]-5-oxopentanoic acid; RGES. Molecular formula: C16H29N7O8. Mole weight: 447.45. | |
| atrolysin F | A 64 kDa hemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that digests the γ chain of fibrinogen. Immunologically distinct from EC 3.4.24.1, atrolysin A. Group: Enzymes. Synonyms: Crotalus atrox metalloendopeptidase; hemorrhagic toxin f; Crotalus atrox metalloendopeptidase f. Enzyme Commission Number: EC 3.4.24.45. CAS No. 172306-52-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4327; atrolysin F; EC 3.4.24.45; 172306-52-4; Crotalus atrox metalloendopeptidase; hemorrhagic toxin f; Crotalus atrox metalloendopeptidase f. Cat No: EXWM-4327. |  |
| atroxase | A nonhemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that cleaves fibrinogen. In peptidase family M12 (astacin family). Group: Enzymes. Enzyme Commission Number: EC 3.4.24.43. CAS No. 181186-94-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4325; atroxase; EC 3.4.24.43; 181186-94-7. Cat No: EXWM-4325. | |
| β-(5-Bromo-2-thienyl)-L-alanine | β-(5-Bromo-2-thienyl)-L-alanine is used as a building block to synthesize fibrinogen receptor antagonists. Synonyms: H-Ala{2-Thienyl(5-Br)}-OH; H-Thi(2)(5-Br)-OH; L-2-(5-Bromothienyl)alanine; (S)-2-Amino-3-(5-bromothiophen-2-yl)propanoic acid; 3-(5-Bromothiophen-2-Yl)-L-Alanine; 3-(5-Bromo-2-thienyl)alanine; beta-(5-Bromo-2-thienyl)-L-alanine; L-α-(5-Bromothienyl)alanine; L-Thi(5-Br)-OH. Grades: ≥ 99% (HPLC). CAS No. 154593-58-5. Molecular formula: C7H8BrNO2S. Mole weight: 250.11. | |
| Cilengitide TFA salt | Cilengitide TFA salt, is a cyclic Arg-Gly-Asp acid pentapeptide that induces anoikis in angiogenic blood vessels and brain tumor, selectively and potently blocks the ligation of theαvβ3 andαvβ5 integrins to provisional matrix proteins such as vitronectin, fibronectin, fibrinogen, von Willebrand factor, osteopontin, and others. Synonyms: Cilengitide trifluoroacetate. Grades: >98%. CAS No. 199807-35-7. Molecular formula: C29H41F3N8O9. Mole weight: 702.68. | |
| Coagulation Factor Calibrator Plasma | The Coagulation Factor Calibrator Plasma is a lyophilized reference plasma intended for use in the calibration of Antigen assays for factor II, factor VII, factor X, factor XI, factor XIII, Protein C, Protein S, Antithrombin III, von Willebrand Factor and fibrinogen by ELISA. It is prepared from a pool of normal citrated human plasma collected from a minimum of 20 donors, buffered with HEPES and stabilizers and lyophilized. Group: Biologicals. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| Fibrin (Bovine) | Fibrinogen has been used in studies of haemostatic therapy in surgical and massive trauma patients. These studies have shown that fibrinogen may prove to be more superior in stopping blood loss when compared to using fresh frozen plasma (FFP). Group: Biochemicals. Alternative Names: Factor I. Grades: Molecular Biology Grade. CAS No. 9001-31-4. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Fibrinopeptide A, human | Fibrinopeptide A, human, located at the NH2-termini of the Aα chain, is a short peptide with 16 residues cleaved from fibrinogen by thrombin. Synonyms: Human fibrinopeptide A; H-Ala-Asp-Ser-Gly-Glu-Gly-Asp-Phe-Leu-Ala-Glu-Gly-Gly-Gly-Val-Arg-OH; L-alanyl-L-alpha-aspartyl-L-seryl-glycyl-L-alpha-glutamyl-glycyl-L-alpha-aspartyl-L-phenylalanyl-L-leucyl-L-alanyl-L-alpha-glutamyl-glycyl-glycyl-glycyl-L-valyl-L-arginine. Grades: ≥95%. CAS No. 25422-31-5. Molecular formula: C63H97N19O26. Mole weight: 1536.56. | |
| Fibrinopeptide A, human TFA | Fibrinopeptide A, human TFA is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH 2 -termini of the Aα chain [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Human fibrinopeptide A TFA. CAS No. 61533-47-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1538A. | |
| [Glu1]-Fibrinopeptide B | [Glu1]-Fibrinopeptide B is derived from fibrinopeptide B amino acid residues 1-14. Human fibrinopeptide B (hFpB), a thrombin-derived proteolytic cleavage product of the fibrinogen B beta-chain, to stimulate neutrophils (PMN), monocytes, and fibroblasts. Uses: Scientific research. Group: Peptides. CAS No. 103213-49-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0308. | |
| GPRP | GPRP is an inhibitor of fibrin polymerization. It binds to fibrinogen (Ki = 400 mM). Synonyms: Gly-pro-arg-pro; L-Proline,glycyl-L-prolyl-L-arginyl-; (S)-1-((S)-2-((S)-1-(2-aminoacetyl)pyrrolidine-2-carboxamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxylic acid. CAS No. 67869-62-9. Molecular formula: C18H31N7O5. Mole weight: 425.48. | |
| GR 144053 trihydrochloride | GR 144053 trihydrochloride is a potent and selective orally bioactive platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist (IC50 = 37 nM). GR 144053 potently inhibits thrombus formation in vivo. Synonyms: GR 144053; GR-144053; GR144053; GR 144053 trihydrochloride. 4-[4-[4-(Aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineacetic acid trihydrochloride. Grades: ≥99% by HPLC. CAS No. 1215333-48-4. Molecular formula: C18H27N5O2.3HCl. Mole weight: 454.83. | |
| H-Arg-Gly-Asp-Cys-OH | H-Arg-Gly-Asp-Cys-OH, a fibronectin binding motif to cell adhesion molecules, inhibits platelet aggregation and fibrinogen binding. Synonyms: RGDC; H-RGDC-OH; L-arginyl-glycyl-L-alpha-aspartyl-L-cysteine; (6S,12S,15R)-1,6-diamino-12-(carboxymethyl)-1-imino-15-(mercaptomethyl)-7,10,13-trioxo-2,8,11,14-tetraazahexadecan-16-oic acid. Grades: 95%. CAS No. 109292-46-8. Molecular formula: C15H27N7O7S. Mole weight: 449.48. | |
| H-Arg-Gly-Glu-Ser-OH | H-Arg-Gly-Glu-Ser-OH is a RGD-related peptide, which is a control of RGDS to inhibit the binding activity of fibrinogen and activated platelet. Synonyms: RGES; H-RGES-OH; L-arginyl-glycyl-L-alpha-glutamyl-L-serine; L-Serine, N-(N-(N-L-arginylglycyl)-L-alpha-glutamyl)-; rgespeptide. Grades: 95%. CAS No. 93674-97-6. Molecular formula: C16H29N7O8. Mole weight: 447.44. | |
| H-Arg-Gly-Glu-Ser-OH.TFA | H-Arg-Gly-Glu-Ser-OH.TFA is a RGD-related peptide, which is a control of RGDS to inhibit the binding activity of fibrinogen and activated platelet. Synonyms: RGES.TFA; H-RGES-OH.TFA; L-arginyl-glycyl-L-alpha-glutamyl-L-serine trifluoroacetic acid. Grades: >98%. Molecular formula: C16H29N7O8.C2HF3O2. Mole weight: 561.47. | |
| Heparin Sodium | Heparin sodium is an anticoagulant, is a kind of mucosaccharide, is extracted from the intestinal mucosa of pigs, cattle, sheep sodium salt glucosamine sulfate, in the human body is secreted by mast cells and naturally exists in the blood. Heparin sodium Chemicalbook can prevent platelet aggregation and destruction, inhibit the transformation of fibrinogen into fibrin monomer, inhibit the formation of thrombin and counter the already formed thrombin, prevent the transformation of prothrombin into thrombin and antithrombin. Synonyms: SODIUM HEPARIN;SODIUM HEPARINATE;REVIPARIN SODIUM;PORCINE HEPARIN SODIUM;BOVINE HEPARIN SODIUM;HEP, NA, BOVINE;HEP, NA, PORCINE;HEPARIN PORCINE SODIUM SALT. CAS No. 9041-8-1. Product ID: PAP-0071. Molecular formula: (C12H16NS2Na3)20. Category: Cardiovascular. Product Keywords: Cardiovascular Series; Heparin Sodium; PAP-0071; Cardiovascular; (C12H16NS2Na3)20; 9041-08-1. Standard: CP. Chemical Name: SODIUM HEPARIN;SODIUM HEPARINATE;REVIPARIN SODIUM;PORCINE HEPARIN SODIUM;BOVINE HEPARIN SODIUM;HEP, NA, BOVINE;HEP, NA, PORCINE;HEPARIN PORCINE SODIUM SALT. Grade: Pharmaceutical Grade. Solubility: H2O: 50 mg/mL, clear, faintly yellow. Storage: 2-8°C. Melting Point: >181°C (dec.). Product Description: Heparin sodium is an anticoagulant, is a kind of mucosaccharide, is extracted from the intestinal mucosa of pigs, cattle, sheep sodium salt glucosamine sulfate, in the human body is secreted by ma |  |
| H-Gly-His-Arg-Pro-NH2 | The fibrin central E region contains two sets of polymeric knobs A and B, which are hidden in fibrinogen but are exposed after thrombin cleavage of fibrinopeptide A (FpA) and fibrinopeptide B (FpB) from the N-terminus of the Aα- and Bβ-chains, respectively. The location of the binding holes and possible models for knob-hole interactions can be known by X-ray crystallographic studies using synthetic peptide analogs of knobs A and B. When fibrinogen fragment D and dual D are crystallized in the presence of two peptide analogs, the knob A peptide mimic H-Gly-Pro-Arg-Pro-NH2 (GPRP-amide) interacts with residues γ364Asp, γ330Asp, γ329Gln, and γ340His found in hole a to form H bonds, the knob B peptide mimic H-Gly-His-Arg-Pro-NH2 (GHRP-amide) interacts with Bβ397Glu, Bβ398Asp, and Bβ432Asp in hole b. Synonyms: GHRP amide; H-GHRP-NH2; glycyl-L-histidyl-L-arginyl-L-prolinamide; Glycyl-L-histidyl-N5-(diaminomethylene)-L-ornithyl-L-prolinamide; (S)-1-((S)-2-((S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxamide. Grades: ≥95%. CAS No. 209623-54-1. Molecular formula: C19H32N10O4. Mole weight: 464.53. | |
| horrilysin | A 56 kDa hemorrhagic endopeptidase from the venom of the timber rattlesnake (Crotalus horridus horridus) that cleaves basement membrane, hide powder and fibrinogen. Group: Enzymes. Synonyms: Crotalus horridus metalloendopeptidase; hemorrhagic proteinase IV; Crotalus horridus horridus venom hemorrhagic proteinase. Enzyme Commission Number: EC 3.4.24.47. CAS No. 84056-81-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4329; horrilysin; EC 3.4.24.47; 84056-81-5; Crotalus horridus metalloendopeptidase; hemorrhagic proteinase IV; Crotalus horridus horridus venom hemorrhagic proteinase. Cat No: EXWM-4329. | |
| Human α-Thrombin | Human α-thrombin is a multifunctional serine protease that plays a pivotal role in the coagulation pathway. Human α-thrombin cleaves fibrinogen and converts it into fibrin. Human α-thrombin can stimulate platelet activation and stabilize fibrin polymers [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.4.21.5; Human Alpha Thrombin. CAS No. 9002-4-4. Pack Sizes: 50 U; 100 U. Product ID: HY-114164A. | |
| kallikrein 8 | The enzyme is activated by removal of an N-terminal prepropeptide. The highest amidolytic activity is observed using Boc-Val-Pro-Arg?7-amido-4-methylcoumarin, which is a substrate of α-thrombin. Substrates lacking basic amino acids in the P1 position are not cleaved. The enzyme degrades casein, fibronectin, gelatin, collagen type IV, fibrinogen, and high-molecular-mass kininogen and is associated with diseases such as ovarian cancer and Alzheimer's disease. Belongs in peptidase family S1A. Group: Enzymes. Synonyms: KLK8; PRSS19; human kallikrein 8; hK8; mK8; ovasin; tumor-associated differentially expressed gene 14; TADG-14; NP; neuropsin. Enzyme Commission Number: EC 3.4.21.118. CAS No. 171715-15-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4113; kallikrein 8; EC 3.4.21.118; 171715-15-4; KLK8; PRSS19; human kallikrein 8; hK8; mK8; ovasin; tumor-associated differentially expressed gene 14; TADG-14; NP; neuropsin. Cat No: EXWM-4113. | |
| Leukadherin-1 (aMb2 Agonist II, CD11b Agonist II, LA1, Mac-1 Agonist II, CR3 Agonist II, CD11b/CD18 Agonist, 4-(5-((3-Benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl)furan-2-yl)-benzoic Acid) | A furanyl thiazolidinone compound that binds CD11b aA/aI domain in a reversible manner and stabilizes aA in a high-affinity binding conformation toward known CD11b/CD18 (aMB2; CR3; Mac-1) ligands, fibrinogen, ICAM-1, and iC3B. Reported to be superior to IMB-10 in enhancing Mac-1-mediated cell adhesion (EC50=4 vs. >50uM on fibrinogen surface). Effectively suppresses leukocyte recruitment in various inflammatory disease models involving mice, rats, and zebrafish embryos in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| mucrolysin | A 94 kDa hemorrhagic and fibrinogenolytic endopeptidase from the Chinese habu snake (Trimeresurus mucrosquamatus) venom. In peptidase family M12 (astacin family). Group: Enzymes. Synonyms: Trimeresurus metalloendopeptidase A; mucrotoxin A. Enzyme Commission Number: EC 3.4.24.54. CAS No. 85898-38-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4336; mucrolysin; EC 3.4.24.54; 85898-38-0; Trimeresurus metalloendopeptidase A; mucrotoxin A. Cat No: EXWM-4336. | |
| Nafamostat | Nafamostat is a broad spectrum serine protease inhibitor and kallikrein inhibitor. It inhibits blood coagulation and used as an anticoagulant. It is also a possible complement inhibitor. It is mainly used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin. It is formulated with HCl salt due to its basic tendencies. Uses: Nafamostat inhibits blood coagulation and used as an anticoagulant. it is also a possible complement inhibitor. it is mainly used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin. Synonyms: FUT-175; FUT 175; FUT175; 6-Amidino-2-naphthyl 4-guanidinobenzoate;(6-carbamimidoylnaphthalen-2-yl) 4-(diaminomethylideneamino)benzoate; Benzoic acid,4-[(aminoiminomethyl)amino]-, 6-(aminoiminomethyl)-2-naphthalenyl ester. Grades: 95%. CAS No. 81525-10-2. Molecular formula: C19H17N5O2. Mole weight: 347.37. | |
| Nafamostat mesilate | Nafamostat Mesylate is a synthetic serine protease inhibitor and an anticoagulant. It is a fast-acting proteolytic inhibitor and used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: 6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate; Nafamostat mesylate; nafamostat mesilate; FUT-175; FUT 175; FUT175. Grades: >98%. CAS No. 82956-11-4. Molecular formula: C21H25N5O8S2. Mole weight: 539.58. | |
| Native Bovine Thrombin | Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. Thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects. Applications: Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of ...Ia; E thrombin; β-thrombin; γ-thrombin. Enzyme Commission Number: EC 3.4.21.5. CAS No. 9002-4-4. Thrombin. Activity: 600-2,000 NIH units/mg protein (biuret) or > 2,000 NIH units/mg protein (E1%/280 = 19.5); > 125 NIH units/mg protein (biuret). Form: Type I, Lyophilized from saline sodium Citrate buffer, pH 6.5; Type II, buffered aqueous solution, In 0.05 M phosphate buffer, pH 7.0. Source: Bovine plasma. Species: Bovine. thrombin; 9002-04-4; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Cat No: NATE-0698. | |
| Native Human Thrombin | Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. Lyophilized powder containing sucrose, sodium chloride and tris. thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects. Group: Enzymes. Synonyms: thrombin; 9002-04-4; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thromb. Enzyme Commission Number: EC 3.4.21.5. CAS No. 9002-4-4. Thrombin. Activity: 600-2,000 NIH units/mg protein (biuret) or > 2,000 NIH units/mg protein (E1%/280 = 19.5); > 125 NIH units/mg protein (biuret). Form: lyophilized powder. Source: Human plasma. Species: Human. thrombin; 9002-04-4; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Cat No: NATE-0699. | |
| Native Porcine Thrombin | Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. Applications: Diagnostic controls, calibrators & standards; immunoassays; testing/assay validation; life science; manufacturing; coagulation/anemia. Group: Enzymes. Synonyms: thrombin; alpha Subunit Thrombin. Thrombin. Mole weight: 362 kDa. Activity: > 1,000 NIH U/mg. Stability: 2 years. Storage: Store at -20°C. Form: Liquid in 0.05 M sodium Citrate, 0.2 M NaCl, 0.1% PEG-8,000, pH 6.5. Source: Porcine Plasma. Species: Porcine. thrombin; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin; alpha Subunit Thrombin. Cat No: NATE-0970. | |
| Native Rabbit Thrombin | Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. The nih assay procedure uses 0.2 ml diluted plasma (1:1 with saline) as a substrate and 0.1 ml of thrombin sample (stabilized in a 1% buffered albumin solution) based on a modification of the method of biggs. only clotting times in the range of 15-25 seconds are used for determining thrombin concentrations. activity is expressed in nih units obtained by direct comparison to a nih thrombin reference standard. Group: Enzymes. Synonyms: thrombin; 9002-04-4; EC 3.4.21. Enzyme Commission Number: EC 3.4.21.5. CAS No. 9002-4-4. Thrombin. Activity: 600-2,000 NIH units/mg protein (biuret) or > 2,000 NIH units/mg protein (E1%/280 = 19.5); > 125 NIH units/mg protein (biuret). Source: Rabbit plasma. Species: Rabbit. thrombin; 9002-04-4; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Cat No: NATE-0700. | |
| Native Rat Thrombin | Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. Thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects. Applications: Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. thrombin has been used in a study to investigate activation of equine platelet-rich plasma. Group: Enzymes. Synonyms: thrombin; 9002-04-4; EC 3.4.21.5; fibrin. Enzyme Commission Number: EC 3.4.21.5. CAS No. 9002-4-4. Thrombin. Activity: 600-2,000 NIH units/mg protein (biuret) or > 2,000 NIH units/mg protein (E1%/280 = 19.5); > 125 NIH units/mg protein (biuret). Form: lyophilized powder. Source: Rat plasma. Species: Rat. thrombin; 9002-04-4; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Cat No: NATE-0701. | |
| Native Serratia sp. Serrapeptase | Serrapeptase is a protein decomposition enzymes produced by bacteria serratia. Can decompose slow bradykinin, fibrin and fibrinogen. Applications: 1. as pharmaceutical raw materials manufacturing injection, oral agents, executive standard: ybh clinic? used for anti-inflammation, eliminate swelling. promote the dissolution of sputum, thick liquid to drain. promote the migration of antibiotics to lesion. 2. plant and animal protein hydrolysate powder (hap, hvp) production applications the flora and fauna of macromolecular protein hydrolysis into small molecular peptides or amino acids, to facilitate the effective absorption and utilization of protein. 3. the application of baki...y used in beer production, proteins can be ruled out "cold cloudy" phenomenon 7. application of textile industry processing of wool, and improve quality 8. application of leather industry made from the hair removal agent. 9. application of feed industry to improve protein utilization and lower costs. Group: Enzymes. Synonyms: Serratiopeptidase; Serratia E-15 protease; serralysin; serrapeptase; serratiapeptase; serratia peptidase; serratio peptidase; serrapeptidase. CAS No. 70851-98-8. Serrapeptase. Source: Serratia sp. Serratiopeptidase; Serratia E-15 protease; serralysin; serrapeptase; serratiapeptase; serratia peptidase; serratio peptidase; serrapeptidase. Cat No: PHAM-381. | |
| N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt | N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt is a chromogenic substrate for plasmin determination, serine protease activity and fibrinogen decomposition determination. Synonyms: N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt; Tos-GPK-pNA; Tos-Gly-Pro-Lys-pNA acetate; N-[(4-methylphenyl)sulfonyl]glycyl-L-prolyl-N-(4-nitrophenyl)-L-lysinamide, monoacetate. Grades: ≥98% by TLC. CAS No. 88793-79-7. Molecular formula: C28H38N6O9S. Mole weight: 634.7. | |
| Q-Peptide | This sequence belongs to the integrin motif of the Ang1 and Ang2 fibrinogen-like (fbg-lk) domain and has been found conserved in mice, rats, humans, and other species. Synonyms: Angiopoietin-1 (312-318) (bovine); L-Serine, L-glutaminyl-L-histidyl-L-arginyl-L-α-glutamyl-L-α-aspartylglycyl-; H-Gln-His-Arg-Glu-Asp-Gly-Ser-OH. Grades: ≥95%. CAS No. 1361235-89-3. Molecular formula: C31H49N13O14. Mole weight: 827.81. | |
| ruberlysin | A 25 kDa hemorrhagic endopeptidase from the venom of the red rattlesnake (Crotalus ruber ruber) that cleaves fibrinogen. In peptidase family M12 (astacin family). Group: Enzymes. Synonyms: Crotalus ruber metalloendopeptidase II; hemorrhagic toxin II. Enzyme Commission Number: EC 3.4.24.48. CAS No. 846020-01-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4330; ruberlysin; EC 3.4.24.48; 846020-01-7; Crotalus ruber metalloendopeptidase II; hemorrhagic toxin II. Cat No: EXWM-4330. | |
| stratum corneum chymotryptic enzyme | This enzyme has wide substrate specificity, being able to degrade heat-denatured bovine casein and the α-chain of native human fibrinogen. It cleaves the B chain of bovine insulin at Leu6?Cya7, Tyr16?Leu17, Phe25?Tyr26 and Tyr26?Thr27. It is thought to play a role in the desquamation (skin-shedding) of the outer layer of skin, the stratum corneum, by degrading intercellular cohesive structures. Belongs in peptidase family S1A. Group: Enzymes. Synonyms: kallikrein 7; SCCE; KLK7; PRSS6; hK7. Enzyme Commission Number: EC 3.4.21.117. CAS No. 155215-90-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4112; stratum corneum chymotryptic enzyme; EC 3.4.21.117; 155215-90-0; kallikrein 7; SCCE; KLK7; PRSS6; hK7. Cat No: EXWM-4112. | |
| Tetrafibricin | Tetrafibricin is a fibrinogen antagonist produced by Str. neyagawaensis NR0577. Tetrafibricin has a strong inhibitory effect on the binding of fibrinogen to the GP IIb/IIIa receptor with an IC50 of 46 nmol/L, and an IC50 of 46 mol/L for the inhibition of HeLa cell toxicity. Synonyms: 11,15,17,19,23,25,27,29,33,37-Decahydroxy-12-methyl-13-oxo-40-amino-2,4,6,8,20,30,34-tetracontaheptaenoic acid; 2,4,6,8,20,30,34-Tetracontaheptaenoic acid, 40-amino-11,15,17,19,23,25,27,29,33,37-decahydroxy-12-methyl-13-oxo-. CAS No. 151705-56-5. Molecular formula: C41H67NO13. Mole weight: 781.97. | |
| thrombin | Formed from prothrombin. More selective than trypsin and plasmin. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Enzyme Commission Number: EC 3.4.21.5. CAS No. 9002-4-4. Thrombin. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4143; thrombin; EC 3.4.21.5; 9002-04-4; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Cat No: EXWM-4143. | |
| Thrombin from Human, Recombinant | Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. Thrombin is the final coagulation protease in regard to hemostasis, promoting both pr ocoagulant and anticoagulant effects. Applications: Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. thrombin has been used in a study to assess in vitro hemostatic properties of french lyophilized plasma. Group: Enzymes. Synonyms: thrombin; EC 3.4.21.5; fibrinogenase; thrombas. Enzyme Commission Number: EC 3.4.21.5. CAS No. 9002-4-4. Purity: > 95% (SDS-PAGE). Thrombin. Storage: -70°C. Form: aqueous solution; supplied as a solution in 20 mM MES, pH 6.0, 500 mM choline chloride. Source: HEK 293 cells. Species: Human. thrombin; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Cat No: NATE-0702. | |
| Thrombin, Pig blood | Thrombin, Pig blood is a key enzyme in the coagulation cascade, responsible for converting fibrinogen into fibrin. Thrombin, Pig blood activates platelet activation, endothelial cell function, and inflammatory responses by binding to PAR-1 and PAR-4 , which triggers G protein-coupled signaling pathways. Thrombin, Pig blood holds promise for research in coagulation and inflammation fields [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9002-4-4. Pack Sizes: 100 KU. Product ID: HY-114164C. | |
| Tirofiban | Tirofiban (L700462) is a selective and reversible platelet integrin receptor ( Gp IIb/IIIa ) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L700462; MK383. CAS No. 144494-65-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17369B. | |
| Tirofiban-butyl-d9, Hydrochloride (N-(Butyl-d9-sulfonyl)-O-[4-(4-piperidynyl)butyl]-L-tyrosine, Hydrochloride) | Labeled Tirofiban, a specific nonpeptide platelet fibrinogen receptor (GPIIb/IIIa) antagonist. An antithrombotic used in the treatment of unstable angina. Group: Biochemicals. Alternative Names: N-(Butyl-d9-sulfonyl)-O-[4-(4-piperidynyl)butyl]-L-tyrosine, Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Tirofiban, Hydrochloride Hydrate (N-(Butylsulfonyl)-O-[4-(4-piperidynyl)butyl]-L-tyrosine, Hydrochloride Hydrate) | A specific nonpeptide platelet fibrinogen receptor (GPIIb/IIIa) antagonist. An antithrombotic used in the treatment of unstable angina. Group: Biochemicals. Alternative Names: N-(Butylsulfonyl)-O-[4-(4-piperidynyl)butyl]-L-tyrosine, Hydrochloride Hydrate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Tirofiban hydrochloride monohydrate | Tirofiban (L700462) hydrochloride monohydrate is a selective and reversible platelet integrin receptor ( Gp IIb/IIIa ) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban hydrochloride monohydrate induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban hydrochloride monohydrate can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L700462 hydrochloride monohydrate; MK383 hydrochloride monohydrate. CAS No. 150915-40-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17369. | |
| Tirofiban Hydrochloride Monohydrate | Tirofiban is a specific nonpeptide platelet fibrinogen receptor (GPIIb/IIIa) antagonist. Tirofiban is an antithrombotic used in the treatment of unstable angina. Uses: The treatment of unstable angina. Synonyms: N-(Butylsulfonyl)-4-(4-(4-piperidyl)butoxy)-L-phenylalanine monohydrochloride monohydrate; Aggrastat; L 700462; L700462; L-700,462; MK-383; MK 383; MK383; Tirofiban; Tirofiban hydrochloride monohydrate. Grades: >98%. CAS No. 150915-40-5. Molecular formula: C22H39ClN2O6S. Mole weight: 495.07. | |
| venombin A | A somewhat thrombin-like enzyme from venoms of snakes of the viper/rattlesnake group. Species variants of the enzyme include ancrod from Agkistrodon rhodostoma (Malayan pit viper) (formerly EC 3.4.21.28), batroxobin from Bothrops atrox (South American pit viper) (formerly EC 3.4.21.29) and crotalase from Crotalus adamanteus (Eastern diamondback rattlesnake) (formerly EC 3.4.21.30). In peptidase family S1 (trypsin family). Does not require activation by Ca2+. Group: Enzymes. Synonyms: α-fibrinogenase; habutobin; zinc metalloproteinase Cbfib1.1; zinc metalloproteinase Cbfib1.2; zinc metalloproteinase Cbfib2; ancrod; (see also Comments). Enzyme Commission Number: EC 3.4.21.74. CAS No. 146240-35-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4166; venombin A; EC 3.4.21.74; 146240-35-9; α-fibrinogenase; habutobin; zinc metalloproteinase Cbfib1.1; zinc metalloproteinase Cbfib1.2; zinc metalloproteinase Cbfib2; ancrod; (see also Comments). Cat No: EXWM-4166. | |
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