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| Product | Description | |
|---|---|---|
| Folic acid dihydrate | Folic acid dihydrate. Group: Biochemicals. Alternative Names: Pteroylglutamic acid. Grades: Highly Purified. CAS No. 75708-92-8. Pack Sizes: 250g, 500g, 1kg. US Biological Life Sciences. |  Worldwide |
| Folic Acid Dihydrate | Folic Acid Dihydrate is the hydrate form of Folic acid, which is used to treat anemia caused by folate deficiency. Synonyms: (S)-2-(4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid dihydrate; L-Glutamic acid, N-(4-(((2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, hydrate (1:2); N-(4-{[(2-Amino-4-oxo-1,4-dihydro-6-pteridinyl)methyl]amino}benzoyl)-L-glutamic acid dihydrate. Grade: ≥95%. CAS No. 75708-92-8. Molecular formula: C19H19N7O6. Mole weight: 477.43. |  |
| Folic Acid, Dihydrate, 97.0-102.0% USP | Assay: Group: Biochemicals. Grades: USP. CAS No. 75708-92-8. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| DL-Methotrexate Dipotassium Salt Dihydrate | DL-Methotrexate Dipotassium Salt Dihydrate is a racemic form of Methotrexate, which is a folic acid antagonist used as an antineoplastic and antirheumatic. Synonyms: N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-glutamic Acid Dipotassium Salt Dihydrate; DL-Amethopterin; Dipotassium Salt Dihydrate; DL-Methotrexate Dipotassium Salt Dihydrate; NSC 117356 Dipotassium Salt Dihydrate. Molecular formula: C20H24K2N8O7. Mole weight: 566.65. | |
| 10-Formyl-7,8-dihydro Folic Acid | 10-Formyl-7,8-dihydro Folic Acid is an impurity of Folic acid, which is used to treat anemia caused by folate deficiency. Synonyms: N-[4-[[(2-Amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-L-glutamic Acid; N-[p-[N-[(2-Amino-7,8-dihydro-4-hydroxy-6-pteridinyl)methyl]formamido]benzoyl]glutamic Acid; N-(10-formyl-7,8-dihydropteroyl)-L-glutamate; N-Formyl-7,8-dihydrofolic Acid; 10-FDHFA; Folinic Acid Impurity F; L-Glutamic acid, N-[4-[[(2-amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-; 10-Formyldihydrofolate; 10-formyldihydrofolic acid; 10-Formyldihydropteroylglutamate. Grade: ≥95%. CAS No. 28459-40-7. Molecular formula: C20H21N7O7. Mole weight: 471.43. | |
| 10-Formyl-7,8-dihydro Folic Acid Disodium Salt | 10-Formyl-7,8-dihydro Folic Acid Disodium Salt is an impurity of Folic acid, which is used to treat anemia caused by folate deficiency. Synonyms: N-[4-[[(2-Amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-L-glutamic Acid Disodium Salt; N-[p-[N-[(2-Amino-7,8-dihydro-4-hydroxy-6-pteridinyl)methyl]formamido]benzoyl]glutamic Acid Disodium Salt; N-[4-[[(2-Amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-L-glutamic Acid Disodium Salt; N-Formyl-7,8-dihydrofolic Acid Disodium Salt; 10-FDHFA Disodium Salt; Folinic Acid Impurity F Disodium Salt; L-Glutamic acid, N-[4-[[(2-amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-, sodium salt (1:2). Grade: 85%. Molecular formula: C20H19N7Na2O7. Mole weight: 515.39. | |
| 10-Formyl Folic Acid | A Folic acid derivative (or folate) found in daily dietary intake that is often used in cancer risk correlation studies. Group: Biochemicals. Alternative Names: N- [4- [ [ (2-Amino-3, 4-dihydro-4-oxo-6-pteridinyl) methyl] formylamino] benzoyl] -L-glutamic Acid; 10-Formylpteroylglutamic Acid; N10-Formylfolic Acid; N- [p- [N- [ (2-Amino-4-hydroxy-6-pteridinyl) methyl] formamido] benzoyl] -glutamic Acid. CAS No. 134-05-4. Pack Sizes: 50mg, 100mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| 2- [4- [Acetyl [ [2- (acetylamino) -3, 4-dihydro-4-oxo-6-pteridinyl] methyl] amino] phenyl] -4, 5-dihydro-5-oxo-4-oxazolepropanoic Acid | 2- [4- [Acetyl [ [2- (acetylamino) -3, 4-dihydro-4-oxo-6-pteridinyl] methyl] amino] phenyl] -4, 5-dihydro-5-oxo-4-oxazolepropanoic Acid is an intermediate in the synthesis of metabolites of Folic Acid (F680300), a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA. Group: Biochemicals. Grades: Highly Purified. CAS No. 78168-20-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C23H21N7O7. US Biological Life Sciences. | Worldwide |
| 2-Acetamido-6-formylpteridin-4-one | Acetyl-6-formylpterin is an inhibitor of mucosal-associated invariant T (MAIT) cell activation.1 It dose-dependently increases the surface expression of MHC-related 1 (Mr1) in WT3 cells overexpressing Mr1 (WT3-m) following incubation with E. coli but does not activate MAIT cells cocultured with WT3-m cells when used at concentrations ranging from 0.23-15uM. Acetyl-6-formylpterin is also a degradation product of folic acid and a precursor in the synthesis of 2-hydroxy-7,8-dihydrofolate, which is a metabolite of para-aminosalicylic acid (PAS) in M. tuberculosis.2. Group: Biochemicals. Alternative Names: N-(6-Formyl-3,4-dihydro-4-oxo-2-pteridinyl)acetamide; 2-Acetamido-4- hydroxy-6-pteridinecarboxalde hyde; NSC 129965; Ac-6-FP. Grades: Highly Purified. CAS No. 29769-49-1. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C9H7N5O3, Molecular Weight: 233.18. US Biological Life Sciences. | Worldwide |
| 4-(N-[2,4-Diamino-6-pteridinylmethyl]amino)benzoic acid sodium salt | 4-(N-[2,4-Diamino-6-pteridinylmethyl]amino)benzoic acid sodium salt is an intermediate for the synthesis of Aminopterin, a folic acid antagonist. Synonyms: Benzoic acid, 4-[[(2,4-diamino-6-pteridinyl)methyl]amino]-, sodium salt (1:1); Benzoic acid, 4-[[(2,4-diamino-6-pteridinyl)methyl]amino]-, monosodium salt; 4-[(2-Amino-4-imino-3,4-dihydropteridin-6-ylmethyl)amino]benzoic acid sodium salt; Sodium 4-(N-[2,4-diamino-6-pteridinylmethyl]amino)benzoate; Sodium 4-{[(2,4-diamino-6-pteridinyl)methyl]amino}benzoate. Grade: 95%. CAS No. 100929-45-1. Molecular formula: C14H12N7NaO2. Mole weight: 333.28. | |
| 7-Cyanomethotrexate Dimethyl Ester | 7-Cyanomethotrexate Dimethyl Ester is an intermediate of Methotrexate, which is a folic acid antagonist used as an antineoplastic and antirheumatic. Uses: An intermediate in the production of methotrexate metabolites. Synonyms: N-[4-[[(2,4-Diamino-7-cyano-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic Acid Dimethyl Ester; Dimethyl N-(4-{[(2,4-diamino-7-cyano-6-pteridinyl)methyl](methyl)amino}benzoyl)-L-glutamate; L-Glutamic acid, N-[4-[[(2,4-diamino-7-cyano-6-pteridinyl)methyl]methylamino]benzoyl]-, dimethyl ester; (S)-Dimethyl 2-(4-(((4-amino-7-cyano-2-imino-2,3-dihydropteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate. Grade: 98%. CAS No. 112163-39-0. Molecular formula: C23H25N9O5. Mole weight: 507.50. | |
| 7-Hydroxymethotrexate | 7-Hydroxymethotrexate is a major metabolite of Methotrexate (MTX; HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5939-37-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-130569. |  |
| Aminopterin | Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a K i of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Aminofolic acid; APGA. CAS No. 54-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14518. | |
| Dapsone Lactose Adduct | A metabolite of Dapsone, which is a synthetic sulfone compound with antimicrobial and anti-inflammatory properties. Dapsone is primarily used to treat Mycobacterium leprae infections (leprosy) and Pneumocystis jirovecii pneumonia, often as part of combination therapy. Dapsone inhibits dihydropteroate synthase, an enzyme involved in folic acid synthesis, thereby interfering with bacterial growth. Grade: ≥95%. Molecular formula: C24H32N2O12S : C24H32N2O12S. Mole weight: 572.58 : 572.58. | |
| D-Folic Acid | One of the impurities of Folic acid. Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. Synonyms: N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-D-glutamic Acid; (R)-2-(4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)amino)benzamido)pentanedioic Acid. CAS No. 65165-91-5. Molecular formula: C19H19N7O6. Mole weight: 441.40. | |
| Diazaquinomycin A | Diazaquinomycin A is produced by the strain of Streptomyces sp.OM-704-KA333. It has anti-gram-positive bacterial activity and has antagonistic effect with metabolism of folic acid. Synonyms: Antibiotic OM 704A; NSC626554; 2,8-Dihydroxy-3,7-dimethyl-4,6-dipropylpyrido[3,2-g]quinoline-5,10-dione. CAS No. 87614-40-2. Molecular formula: C20H22N2O4. Mole weight: 354.41. | |
| dihydrofolate reductase | The enzyme from animals and some micro-organisms also slowly reduces folate to 5,6,7,8-tetrahydrofolate. Group: Enzymes. Synonyms: tetrahydrofolate dehydrogenase; DHFR; pteridine reductase:dihydrofolate reductase; dihydrofolate reductase:thymidylate synthase; thymidylate synthetase-dihydrofolate reductase; folic acid reductase; folic reductase; dihydrofolic acid reductase; dihydrofolic reductase; 7,8-dihydrofolate reductase; NADPH-dihydrofolate reductase. Enzyme Commission Number: EC 1.5.1.3. CAS No. 9002-3-3. Dihydrofolate Reductase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1511; dihydrofolate reductase; EC 1.5.1.3; 9002-03-3; tetrahydrofolate dehydrogenase; DHFR; pteridine reductase:dihydrofolate reductase; dihydrofolate reductase:thymidylate synthase; thymidylate synthetase-dihydrofolate reductase; folic acid reductase; folic reductase; dihydrofolic acid reductase; dihydrofolic reductase; 7,8-dihydrofolate reductase; NADPH-dihydrofolate reductase. Cat No: EXWM-1511. |  |
| Folic acid | Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. The combined use of enalapril and folic acid, compared with enalapril alone, significantly reduced the risk of first stroke. High folic acid intakes and MTHFR gene variations seem not to be associated with helping women to achieve pregnancy during or after fertility treatment. Uses: Hematopoietic vitamin. Synonyms: n-4-[(2-amido-4-oxo-1,4-dihydro-6-terene)methylamino]benzoyl-l-glutamic acid. Grade: >98%. CAS No. 59-30-3. Molecular formula: C19H19N7O6. Mole weight: 441.40. | |
| Folic Acid | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitesstandards for environmental regulatory methodspharma & vet compounds & metabolitesapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Folipac, Millafol, Folicet, Folic acid,Folic Acid, N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid, Folsan, Folacid, Vitamin Be, Folbal, Foldine, Folsaure, PGA, Folsav, NSC 3073, Acifolic, Liver Lactobacillus casei factor, Pteroyl-L-monoglutamic acid, Aspol, Pteroylmonoglutamic acid, Folacin, Folcidin, Incafolic, Folettes, Folvite, Dosfolat B activ, Pteroyl-L-glutamic acid, Foliamin, Vitamin M, Vitamin Bc, Cytofol, Folovit, Pteroylglutamic acid. |  |
| Folic Acid-d2 | A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate. Group: Biochemicals. Alternative Names: N-[4-[[ (2-Amino-3, 4-dihydro-4-oxo-6-pteridinyl) methyl]amino]benzoyl]-L-glutamic Acid-d2; Acifolic-d2; Aspol-d2; Cytofol-d2; Folacid-d2; Folacin-d2; Folbal-d2; Folcidin-d2; Foldine-d2; Folettes-d2; Foliamin-d2; Folicet-d2; Folipac-d2; Folovit-d2; Folsan-d2; Folsaure-d2; Folsav-d2; Folvite-d2; Incafolic-d2; Millafol-d2; Pteroyl-L-monoglutamic Acid-d2; Pteroylglutamic Acid-d2; Pteroylmonoglutamic Acid-d2; Vitamin Bc-d2; Vitamin Be-d2; Vitamin M-d2; NSC 3073-d2. Grades: Highly Purified. CAS No. 69022-87-3. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Folic Acid-[d2] | Folic Acid-[d2] is the labelled analogue of Folic acid. Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. Uses: A vitamin needed to synthesize dna, conduct dna repair and methylate dna, it also acts as a cofactor in biological reactions involving folate. Synonyms: Folic Acid D2; N-(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)(2H2)methyl]amino}benzoyl)-L-glutamic acid. CAS No. 69022-87-3. Molecular formula: C19H17D2N7O6. Mole weight: 443.41. | |
| Folic Acid-d4 (N-[4-[[ (2-Amino-1, 4-dihydro-4-oxo-6-pteridinyl) methyl]amino]benzoyl-2, 3, 5, 6-d4]-L-. glutamic Acid) | A labeled vitamers of folic acid used as internal standards in stable isotope dilution assays. Group: Biochemicals. Alternative Names: N-[4-[[ (2-Amino-1, 4-dihydro-4-oxo-6-pteridinyl) methyl]amino]benzoyl-2, 3, 5, 6-d4]-L-glutamic Acid. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Folic Acid EP Impurity C | Folic Acid EP Impurity C is the isomer of Folic acid, which is used to treat anemia caused by folate deficiency. Uses: The 7-isomer of pteroylglutamic acid. Synonyms: Isofolic acid; N-[4-[[(2-Amino-1,4-dihydro-4-oxo-7-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid; N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)amino)methyl)benzoyl)glutamic acid. Grade: ≥95%. CAS No. 47707-78-8. Molecular formula: C19H19N7O6. Mole weight: 441.40. | |
| Folic Acid EP Impurity E | One of the impurities of Folic acid. Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. Synonyms: 6-Pterinyl Folic Acid; N-[4-[Bis[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid. Grade: 95%. CAS No. 1391068-26-0. Molecular formula: C26H24N12O7. Mole weight: 616.55. | |
| Folic acid hydrate EP Impurity G | One of the impurities of Folic acid. Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. Synonyms: (S)-2-(4-((2-Amino-7-methyl-4-oxo-1,4-dihydropteridin-6-yl)amino)benzamido)pentanedioic acid; N-[4-[(2-Amino-3,4-dihydro-7-methyl-4-oxo-6-pteridinyl)amino]benzoyl]-L-glutamic acid. Grade: 95%. CAS No. 2734707-85-6. Molecular formula: C19H19N7O6. Mole weight: 441.40. | |
| Folic Acid Hydrate EP Impurity H | One of the impurities of Folic acid. Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate. Synonyms: N-[4-[[N-[4-[[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]benzoyl]-L-γ-glutamyl]amino]benzoyl]-L-glutamic Acid. CAS No. 2366274-27-1. Molecular formula: C31H31N9O10. Mole weight: 689.64. | |
| Folic Acid (Vitamin B9, Pteroylglutamic acid, Folacin, PteGlu) USP | A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate. Group: Biochemicals. Alternative Names: PteGlu; ; N-[4-[[ (2-Amino-3, 4-dihydro-4-oxo-6-pteridinyl) methyl]amino]benzoyl]-L-glutamic Acid; Acifolic; Aspol; Cytofol; Folacid; Folacin; Folbal; Folcidin; Foldine; Folettes; Foliamin; Folicet; Folipac; Folovit; Folsan; Folsaure; Folsav; Folvite; Incafolic; Millafol; Pteroyl-L-monoglutamic Acid; Pteroylglutamic Acid; Pteroylmonoglutamic Acid; Vitamin Bc; Vitamin Be; Vitamin M; NSC 3073. Grades: USP. CAS No. 59-30-3. Pack Sizes: 10g, 25g, 100g, 250g, 500g. Molecular Formula: C??H??N?O?, Molecular Weight: 441.4. US Biological Life Sciences. | Worldwide |
| Folinic acid | Folinic acid is an adjuvant used in cancer chemotherapy involving the drug methotrexate. It is a 5-formyl derivative of tetrahydrofolic acid and readily converted to other reduced folic acid derivatives, thus, has vitamin activity that is equivalent to that of folic acid. Since it does not require the action of dihydrofolate reductase for its conversion, its function as a vitamin is unaffected by inhibition of this enzyme by drugs such as methotrexate. Synonyms: leucovorin. Grade: >98%. CAS No. 58-05-9. Molecular formula: C20H23N7O7. Mole weight: 473.44. | |
| Folinic acid calcium salt | Folinic acid calcium salt offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. Calcium folinate is also used in mutagenisis and cancer research. Applications: A compound that reduces the effect of folic acid antagonists. Group: Coenzymes. Synonyms: Leucovorin calcium salt; Citrovorum factor calcium salt; Calcium folinate. CAS No. 1492-18-8. Purity: ≥98%. Mole weight: 511.5. Appearance: Powder. Form: Solid. Leucovorin calcium salt; Citrovorum factor calcium salt; Calcium folinate; Folinic acid calcium salt; 1492-18-8. Cat No: COEC-033. | |
| Methopterine | Methopterine is a Folic acid analogue. Methopterine is effective in the treatment of ectopic pregnancy. Group: Biochemicals. Alternative Names: N- [4- [ [ (2-Amino-3, 4-dihydro-4-oxo-6-pteridinyl) methyl] methylamino] benzoyl] -L-glutamic Acid; N- [p- [ [ (2-Amino-3, 4-dihydro-4-oxo-6-pteridinyl) methyl] methylamino] benzoyl] - L-glutamic Acid; N- [p- [ [ (2-Amino-4-hydroxy-6-pteridinyl) methyl] methylamino] benzoyl] glutamic Acid; N- [4- [ [ (2-Amino-1, 4-dihydro-4-oxo-6-pteridinyl) methyl] methylamino] benzoyl] -L-glutamic Acid; 10-Methylfolic Acid; N10-Methyl Folic Acid; 10-Methylpteroylglutamic Acid; Methopterin; Methopterine; N10-Methylpteroylglutamic Acid; NSC 107144. Grades: Highly Purified. CAS No. 2410-93-7. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Methopterine-d3 | Labeled Methopterine. Methopterine is a Folic acid analogue. Methopterine is effective in the treatment of ectopic pregnancy. Group: Biochemicals. Alternative Names: N-[4-[[ (2-Amino-3, 4-dihydro-4-oxo-6-pteridinyl) methyl]methylamino-d3]benzoyl]-L-glutamic Acid; N-[p-[[ (2-Amino-3, 4-dihydro-4-oxo-6-pteridinyl) methyl]methylamino-d3]benzoyl]- L-glutamic acid; N-[p-[[ (2-Amino-4-hydroxy-6-pteridinyl) methyl]methylamino-d3]benzoyl]glutamic Acid; N-[4-[[ (2-Amino-1, 4-dihydro-4-oxo-6-pteridinyl) methyl]methylamino-d3]benzoyl]-L-glutamic Acid; 10-Methylfolic Acid-d3; N10-Methyl Folic Acid-d3; 10-(Methyl-d3)pteroylglutamic Acid; Methopterin-d3; Methopterine-d3; N10-(Methyl-d3)pteroylglutamic Acid; NSC 107144-d3. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Methotrexate | Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Amethopterin; CL14377; WR19039. CAS No. 59-05-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14519. | |
| Methotrexate disodium | Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia)[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Amethopterin disodium; CL14377 disodium; WR19039 disodium. CAS No. 7413-34-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14519A. | |
| N10- (Trifluoroacetyl) pteroic acid | N10-Trifluoroacetylpteroic acid is a derivative of Pteroic acid, both of which are used as reagents to synthesize target ligands, like Folic acid, that have the ability to deliver chemotherapeutic agents specifically to cancer cells. Group: Biochemicals. Alternative Names: 4-[[ (2-Amino-3, 4-dihydro-4-oxo-6-pteridinyl) methyl] (2, 2, 2-trifluoroacetyl) amino]benzoic Acid; 4-[[ (2-Amino-1, 4-dihydro-4-oxo-6-pteridinyl) methyl] (trifluoroacetyl) amino]benzoic Acid. Grades: Highly Purified. CAS No. 37793-53-6. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C??H??F?N?O?, Molecular Weight: 408.29. US Biological Life Sciences. | Worldwide |
| N-Acetyl Folic Acid-d4 | Intermediate in the production of labeled Folic Acid. Group: Biochemicals. Alternative Names: N- [4- [ [ [2- (Acetylamino) -1, 4-dihydro-4-oxo-6-pteridinyl] methyl] amino] benzoyl-2, 3, 5, 6-d4] -L-glutamic Acid. Grades: Highly Purified. CAS No. 461426-36-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Pyrimethamine | Pyrimethamine is a medication used for protozoal infections. It could interfere with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase. Synonyms: Pirimecidan; Pirimetamin; RP 4753; RP4753; RP-4753. Grade: >98%. CAS No. 58-14-0. Molecular formula: C12H13ClN4. Mole weight: 248.71. | |
| Pyrimethamine | Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic - folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pirimecidan; Pirimetamin; RP 4753. CAS No. 58-14-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-18062. | |
| Sulfacetamide-[13C6] | Sulfacetamide-[13C6] is the labelled analogue of Sulfacetamide. Sulfacetamide is a sulfonamide antibiotic as a dihydropteroate Synthase inhibitor. It is a competitive inhibitor of bacterial para-aminobenzoic acid, which is required for bacterial synthesis of folic acid. Sulfacetamide is used for the treatment of skin infections and urinary tract infections. It is also used to treat acne and seborrheic dermatitis. Synonyms: Sulfacetamide-13C6; N-Acetyl-4-aminobenzene-13C6-sulfonamide; N-[(4-aminophenyl)sulfonyl]acetamide-13C6; 4-(Acetylaminosulfonyl)aniline-13C6; Acetocid-13C6; Acetosulfamine-13C6; Formosulfacetamide-13C6; N-(p-Aminophenylsulfonyl)acetamide-13C6; N-Sulfanilyacetamide-13C6. Grade: >98%. Molecular formula: C2[13C]6H10N2O3S. Mole weight: 220.20. | |
| Sulfadimidine-[13C6] | Sulfadimidine-[13C6] is the labelled analogue of Sulfadimidine, which is a sulfonamide antibacterial. It competitively inhibits dihydropteroate synthase and interferes with folic acid synthesis. Synonyms: Sulfadimidine-13C6; 4-Amino-N-(4,6-dimethylpyrimidin-2-yl)-benzene-13C6-sulfonamide; 4-Amino-N-(4,6-Dimethyl-2-pyrimidinyl)benzenesulfonamide-13C6; Azolmetazin-13C6; Sulfamezathine-13C6; Diazil-13C6. Grade: 95% by HPLC; 98% atom 13C. CAS No. 77643-91-5. Molecular formula: C6[13C]6H14N4O2S. Mole weight: 284.29. | |
| Sulfadoxine-[d3] | Sulfadoxine-[d3] is the labelled analogue of Sulfadoxine, which is an antibacterial. It competitively inhibits dihydropteroate synthase and interferes with folic acid synthesis. Synonyms: Sulfadoxine-D3; 4-Amino-N-(5-methoxy-6-methoxy-D3-pyrimidin-4-yl)-benzenesulfonamide; 4-Amino-N-[5-methoxy-6-(methoxy-d3)-4-pyrimidinyl]benzenesulfonamide. Grade: 95% by HPLC; 98% atom D. CAS No. 1262770-70-6. Molecular formula: C12H11D3N4O4S. Mole weight: 313.35. | |
| Sulfamethazine | Sulfamethazine is a sulfonamide antibacterial agent that competitively inhibits dihydrospteric acid synthase, blocks the synthesis of folic acid and inhibits growth and proliferation. It can be used to treat pasteurosis, mastitis, urinary tract infections caused by sensitive bacteria in livestock, and can also be used for swine atrophic rhinitis, streptococcal disease, swine toxoplasmosis and coccidiosis. Uses: Anti-infective agents. Synonyms: HSDB 4157; HSDB-4157; HSDB4157; Sulfadimidine; Intradine; Kelametazine; 4-Amino-N-(4,6-Dimethyl-2-pyrimidinyl)benzenesulfonamide; Azolmetazin; Diazil. Grade: >98%. CAS No. 57-68-1. Molecular formula: C12H14N4O2S. Mole weight: 278.33. | |
| Sulfamonomethoxine | Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate. Uses: Scientific research. Group: Signaling pathways. CAS No. 1220-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0946. | |
| Sulfamonomethoxine sodium | Sulfamonomethoxine sodium is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 38006-08-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W097570. | |
| Trimethoprim | Trimethoprim is a bacteriostatic antibiotic used mainly in the prophylaxis and treatment of urinary tract infections. It caused induction of DnaK, DnaJ, GroEL, ClpB, and IbpA/B Hsps. It binds to dihydrofolate reductase and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). Uses: Anti-infective agents, urinary; antimalarials; antimetabolites; folic acid antagonists. Synonyms: Trimpex; Proloprim. Grade: >98%. CAS No. 738-70-5. Molecular formula: C14H18N4O3. Mole weight: 290.32. | |
| Trimetrexate glucuronate | Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-898 glucuronate. CAS No. 82952-64-5. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-103396. | |
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