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2,3-di-O-acetyl-6-O-tert-butyldimethylsilyl-gamma-cyclodextrin is a modified cyclodextrin used in enhancing the solubility and stability of drugs, improving their bioavailability. It is often employed in developing formulations for poorly soluble drugs. Synonyms: Octakis-(2,3-di-O-acetyl-6-O-tert-butyldimethylsilyl)-γ-cyclodextrin. Molecular formula: C12H224O56SI8. Mole weight: 2313.18.
2,3-di-O-benzyl-6-O-tert-butyldimethylsilyl-gamma-cyclodextrin is a modified cyclodextrin used in the formation of complex structures for the delivery of various drugs. Specifically, it assists in improving the solubility and bioavailability of poorly soluble pharmaceuticals. Synonyms: Octakis-(2,3-di-O-benzyl-6-O-tert-butyldimethylsilyl)-γ-cyclodextrin. Molecular formula: C208H288O40SI8. Mole weight: 4475.79.
2,3-di-O-methyl-6-O-tert-butyldimethylsilyl-gamma-cyclodextrin is primarily utilized as a chiral selective medium in pharmaceutical research. It aids in the separation of drug stereoisomers, thereby optimizing therapeutic effectiveness and minimizing side effects. Synonyms: Octakis-(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-γ-cyclodextrin. Molecular formula: C112H224O40SI8. Mole weight: 3258.25.
2,6-di-tert-butyldimethylsilyl-gamma-cyclodextrin
2,6-di-tert-butyldimethylsilyl-gamma-cyclodextrin is a versatile biomaterial employed to enhance the solubility and stability of pharmaceutical drugs, especially hydrophobic compounds. This advanced cyclodextrin derivative shows immense potential in the drug development of various diseases by improving drug delivery, prolonging drug release, and increasing drug efficacy. Synonyms: Octakis-(2,6-di-O-tert-butyldimethylsilyl)-γ-cyclodextrin. Molecular formula: C144H304O40Si16. Mole weight: 3125.30.
3,6-di-tert-butylmethylsilyl-gamma-cyclodextrin
3,6-di-tert-butylmethylsilyl-gamma-cyclodextrin is a cutting-edge biomolecule employed in the targeted delivery of drugs, particularly in research on various diseases. With enhanced stability and solubility, it enables efficient encapsulation and controlled release of pharmaceuticals. Synonyms: Octakis-(3,6-di-O-tert-butyldimethylsilyl)-γ-cyclodextrin. Molecular formula: C144H304O40SI16. Mole weight: 4738.47.
6-Mono-tert-butyldimethylsilyl-gamma-cyclodextrin
6-Mono-tert-butyldimethylsilyl-gamma-cyclodextrin, an immensely versatile compound, finds its application in drug delivery systems and pharmaceutical research. Its profound impact on enhancing the solubility and stability of hydrophobic drugs renders it indispensable in the treatment of an array of diseases, encompassing cancer and microbial infections. Operating as a catalyst for improved drug efficacy, elevated bioavailability, and diminished toxicity, this compound emerges as an invaluable asset in the biomedical industry. Molecular formula: C54H94O40SI. Mole weight: 1542.27.
N-Alpha-(9-fluorenylmethyloxycarbonyl)-gamma-tert-butyl-L-glutamol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-alpha-(9-Fluorenylmethyloxycarbonyl)-gamma-tert-butyl-L-glutamol;Fmoc-Glutamol(OBut). Product Category: Heterocyclic Organic Compound. CAS No. 153815-59-9. Molecular formula: C24H29NO5. Mole weight: 411.49. Product ID: ACM153815599. Alfa Chemistry ISO 9001:2015 Certified.
N-Formyl gamma-carboxyglutamic acid gamma,gamma-di-tert-butyl 3-ethyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(Formylamino)-1,1,3-propanetricarboxylic Acid 1,1-Bis(1,1-dimethylethyl) 3-Ethyl Ester. Product Category: Heterocyclic Organic Compound. CAS No. 75117-30-5. Molecular formula: C17H29NO7. Mole weight: 359.41. Purity: 0.96. IUPACName: 1-O,1-O-ditert-butyl 3-O-ethyl 3-formamidopropane-1,1,3-tricarboxylate. Product ID: ACM75117305. Alfa Chemistry ISO 9001:2015 Certified.
1-Methyl-3,3-diphenylpropylamine
1-Methyl-3,3-diphenylpropylamine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-METHYL-3,3-DIPHENYLPROPYLAMINE;RARECHEM AN KC 0196;Benzenepropanamine, N-(1,1-dimethylethyl)-alpha-methyl-gamma-phenyl-;Bicor;N-(tert-Butyl)-4,4-diphenyl-2-butanamine;N-tert-Butyl-1-methyl-3,3-diphenylpropylamine;Propylamine, N-tert-butyl-1-methyl-3,3-. Product Category: Heterocyclic Organic Compound. CAS No. 15793-40-5. Molecular formula: C16H19N. Mole weight: 225.33. Product ID: ACM15793405. Alfa Chemistry ISO 9001:2015 Certified.
2-Methylpropene-[1,1-d2]
2-Methylpropene-[1,1-d2]. Synonyms: 2-Methylpropene-1,1-D2; Isobutene-d2; 2-Methylpropene-d2; 2-methylprop-1-ene-d2; 2-Methyl-1-propene-d2; 1,1-Dimethylethylene-d2; Isopropylidenemethylene-d2; Methylpropene-d2; gamma-Butylene-d2. Grade: 98%; 98% atom D. CAS No. 1560-59-4. Molecular formula: C4H6D2. Mole weight: 58.12.
2-Methylpropene-[d3]
2-Methylpropene-[d3]. Synonyms: 2-Methyl-D3-propene; Isobutene-d3; 2-Methylpropene-d3; 2-methylprop-1-ene-d3; 2-Methyl-1-propene-d3; 1,1-Dimethylethylene-d3; Isopropylidenemethylene-d3; Methylpropene-d3; gamma-Butylene-d3. Grade: 98%; 99% atom D. CAS No. 110597-10-9. Molecular formula: C4H5D3. Mole weight: 59.13.
5-Azido-6-O-(tert-butyldimethylsilyl)-2,3-O-isopropylidene L-gulono-1,4-lactone is a multifaceted compound acting as a precursor in pharmaceutical drug research and development. Furthermore, it serves as a pivotal asset in the pursuit of groundbreaking drug discovery endeavors, targeting meticulously defined diseases or pathways. Synonyms: 5-Azido-5-deoxy-6-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-D-mannonic acid gamma-lactone. CAS No. 118464-49-6. Molecular formula: C15H27N3O5Si. Mole weight: 357.48.
5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-D-ribono-1,4-lactone, a paramount intermediary chemical constituent, has been widely exploited in synthesizing ribonucleoside analogues that aim to curb viral maladies, inclusive of hepatitis C and HIV. Furthermore, its application extends to the production of sundry carbohydrates, nucleotides, and nucleosides that exhibit efficacious anti-carcinogenic and antiviral characteristics. Synonyms: 5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-D-ribono-1,4-lactone; 5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-D-ribonic acid gamma-lactone; 5-o-t-Butyldimethylsilyl-2,3-o-isopropylidine-D-ribonolactone; 2-O,3-O-Isopropylidene-5-O-(tert-butyldimethylsilyl)-D-ribonic acid gamma-lactone; 5-O-[(1,1-Dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-D-ribonic acid γ-lactone. Grade: ≥96%. CAS No. 75467-36-6. Molecular formula: C14H26O5Si. Mole weight: 302.44.
5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-L-lyxono-1,4-lactone is a highly complex chemical compound employed in the fabrication of biologically active molecules. Employed extensively in the pharmaceutical domain, the compound serves as an instrumental ingredient for synthesizing medicaments to combat a plethora of maladies, ranging from common viral infections to life-threatening cancerous growths. It stands apart due to its unique molecular form and serves as a chiral foundational block, allowing drug discovery and development to progress forward in a more comprehensive manner. Synonyms: (3aR,6S,6aR)-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxol-4-one; 5-O-[(tert-Butyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-L-lyxonic acid gamma-lactone; (3aR,6S,6aR)-6-({[Dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one; L-Lyxonic acid, 5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-, γ-lactone. Grade: 95%. CAS No. 1044813-00-4. Molecular formula: C14H26O5Si. Mole weight: 302.44.
Beta-t-butyl-D-alanine
Beta-t-butyl-D-alanine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Methyl-D-leucine, 88319-43-1, 3-tert-butyl-D-alanine, Methyl1-aminomethyl-cyclohexanecarboxylate, (2R)-2-amino-4,4-dimethylpentanoic acid, (R)-3-Amino-4,4-dimethyl-pentanoic acid, (R)-2-AMINO-4,4-DIMETHYL-PENTANOIC ACID, AmbotzHAA8620, H-D-NPTGLY-OH, AC1OCTS7, BETA-TBU-D-ALA-OH, H-D-ALA(TBU)-OH, H-D-NEOPENTYLGLY-OH, D-GAMMA-METHYLLEUCINE, H-BETA-TBU-D-ALA-OH, H-GAMMA-ME-D-LEU-OH, BETA-T-BUTYL-D-ALANINE, CTK8F5211, BETA-TERT-BUTYL-D-ALANINE, MolPort-008-268-123. Product Category: Heterocyclic Organic Compound. CAS No. 88319-43-1. Molecular formula: C7H15NO2. Mole weight: 145.2. Purity: 0.96. IUPACName: (2R)-2-amino-4,4-dimethylpentanoic acid. Density: 1.023g/cm³. Product ID: ACM88319431. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-D-Glu(OtBu)-Wang Resin. Group: Fmoc-amino acid-wang resins. Alternative Names: N-Fmoc-D-glutamic acid gamma-t-butyl ester Wang resin. Pack Sizes: 5g, 25g.
Fmoc-Gla(OtBu)2-OH
Fmoc-Gla(OtBu)2-OH is a building block for the introduction of γ-carboxyglutamic acid (Gla). γ-Carboxylation of glutamic acid is a rare post-translational modification that occurs in blood coagulation factors and in some snake and cone snail venoms. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Gla(OtBu)2-OH, Fmoc-γ-carboxy-Glu(OtBu) 2-OH, Fmoc-gamma-carboxy-L-glutamic acid gamma,gamma-di-t-butyl ester. Product Category: Amino Acids. CAS No. 111662-64-7. Molecular formula: C29H35NO8. Mole weight: 525.59. Purity: Peak Area by HPLC ≥95%. Product ID: ACM111662647-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Glu(OtBu)-Wang Resin
Fmoc-Glu(OtBu)-Wang Resin. Group: Fmoc-amino acid-wang resins. Alternative Names: N-Fmoc-L-glutamic acid gamma-t-butyl ester Wang resin. Pack Sizes: 5g, 25g.
Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: L-Glutamic acid gamma-t-butyl ester 2-chlorotrityl resin. Pack Sizes: 5g, 25g.
Lanolin
Lanolin is a pale yellow-colored, unctuous, waxy substance with a faint, characteristic odor. Melted lanolin is a clear or almost clear, yellow liquid. Synonyms: Adeps lanae; cera lanae; E913; lanolina; lanolin anhydrous; Protalan anhydrous; purified lanolin; refined wool fat. CAS No. 8006-54-0. Product ID: PE-0533. Category: Emulsifying Agents; Ointment Base. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0533; Lanolin; Emulsifying Agents; Ointment Base; ; 8006-54-0. UNII: 7EV65EAW6H. Chemical Name: Anhydrous lanolin. Grade: Pharmceutical Excipients. Administration route: Ophthalmic, otic, topical, and vaginal. Dosage Form: Ophthalmic, otic, topical, and vaginal preparations. Stability and Storage Conditions: Lanolin may gradually undergo autoxidation during storage. To inhibit this process, the inclusion of butylated hydroxytoluene is permitted as an antioxidant. Exposure to excessive or prolonged heating may cause anhydrous lanolin to darken in color and develop a strong rancidlike odor. However, lanolin may be sterilized by dry heat at 150°C. Ophthalmic ointments containing lanolin may be sterilized by filtration or by exposure to gamma irradiation. Lanolin should be stored in a well-filled, well-closed container protected from light, in a cool, dry place. Normal storage life is 2 years. Source and Preparation: Lanolin is a naturally occurring wax-like material obtained from the wool of s
Proteasome inhibitor i. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CARBOBENZOXY-L-ISOLEUCYL-GAMMA-T-BUTYL-L-GLUTAMYL-L-ALANYL-L-LEUCINAL;BENZYLOXYCARBONYL-L-ISOLEUCYL-[(2S)-2-AMINO-4-(T-BUTYLOXYCARBONYL)BUTANOYL]-L-ALANYL-L-LEUCINAL;PROTEASOME INHIBITOR I;PROTEASOME INHIBITOR I (ALDEHYDE);PROTEASOME INHIBITOR PSI;PSI;N-. Product Category: Heterocyclic Organic Compound. CAS No. 158442-41-2. Molecular formula: C32H50N4O8. Mole weight: 618.76. Purity: >90 %. Product ID: ACM158442412. Alfa Chemistry ISO 9001:2015 Certified.
Trimethyl-[4-[4-(methylcarbamoyloxy)phenyl]butan-2-yl]azanium iodide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ammonium, (4-(4-(methylcarbamoyloxy)phenyl)-sec-butyl)trimethyl-, iodide, Carbamic acid, methyl-, 4-(3-(trimethylammonio)butyl)phenyl ester, iodide, AMMONIUM, (4-(4-HYDROXYPHENYL)-sec-BUTYL)TRIMETHYL-, IODIDE, METHYLCARBAMATE, Carbamic acid, N-methyl-, 4-(gamma-dimethylamino-n-butyl)phenyl ester, methiodide, 64046-04-4, AC1L2G8Q, LS-18403, N,N,N-trimethyl-4-{4-[(methylcarbamoyl)oxy]phenyl}butan-2-aminium iodide, trimethyl-[4-[4-(methylcarbamoyloxy)phenyl]butan-2-yl]azanium iodide. Product Category: Heterocyclic Organic Compound. CAS No. 64046-04-4. Molecular formula: C15H25IN2O2. Mole weight: 392.276 g/mol. Purity: 0.96. IUPACName: trimethyl-[4-[4-(methylcarbamoyloxy)phenyl]butan-2-yl]azanium;iodide. Canonical SMILES: CC(CCC1=CC=C(C=C1)OC(=O)NC)[N+](C)(C)C.[I-]. Product ID: ACM64046044. Alfa Chemistry ISO 9001:2015 Certified.
Trypanothione
Trypanothione is utilized as a substrate by trypanothione reductase, a unique enzyme found in trypanosomes and leishmanias (Km = 51 μM). Synonyms: Oxidized trypanothione; N(1),N(8)-Bis(gamma-glu-hemi-cys-gly)sperimidine; L-γ-Glutamyl-L-cysteinyl-N-[3-[[4-[[N-(N-L-γ-glutamyl-L-cysteinyl)glycyl]amino]butyl]amino]propyl]-glycinamide Cyclic (2→3)-disulfide; TS2. CAS No. 96304-42-6. Molecular formula: C27H47N9O10S2. Mole weight: 721.85.
Z-Ile-Leu-aldehyde ia a cell-permeable and reversible inhibitor that inhibits γ-secretase and Notch signaling. It induces apoptosis of murine MOPC315.BM myeloma cells with high Notch activity in vitro. It has potent anti-MM activity and reduces osteolytic lesions in vivo. Uses: Gamma secretase inhibitors and modulators. Synonyms: Z-IL-CHO; GSI-XII; Z-Ile-Leu-al; Z Ile Leu al; Z IL CHO; Gamma-secretase inhibitor XII; [(1S,2S)-1-((S)-1-Formyl-3-methyl-butylcarbamoyl)-2-methyl-butyl]-carbamic acid benzyl ester; Benzyl ((2S,3S)-3-methyl-1-(((S)-4-methyl-1-oxopentan-2-yl)amino)-1-oxopentan-2-yl)carbamate; N-benzyloxycarbonyl-L-isoleucyl-L-leucinal. Grade: ≥95%. CAS No. 161710-10-7. Molecular formula: C20H30N2O4. Mole weight: 362.46.
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