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| Product | Description | |
|---|---|---|
| Glucagon (1-29), bovine, human | Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis [1]. Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Glucagon. CAS No. 16941-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0082. |  |
| Glucagon (1-29), bovine, human hydrochloride | Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis [1]. Glucagon (1-29), bovine, human, porcine hydrochloride activates HNF4α and increases HNF4α phosphorylation [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Glucagon hydrochloride. CAS No. 28270-04-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0082A. | |
| Glucagon (19-29) (human, rat, porcine) | Glucagon is an endogenous short peptide. Synonyms: Miniglucagon (human, rat, porcine). Grades: >95%. CAS No. 64790-15-4. Molecular formula: C61H89N15O18S. Mole weight: 1352.5. |  |
| Glucagon-like peptide 1 (1-37), human | Glucagon-like peptide 1 (1-37) is a pancreatic hormone synthesized by post-translational processing of proglucagon. It decreases plasma glucose level in high-fat-fed mice when administered at 25 nmol/kg. Glucagon-like peptide 1 (1-37) exhibits no effect on food intake in rats and does not enhance pancreatic insulin secretion. However it induces insulin expression in intestinal epithelial cells, which can restore glucose homeostasis when implanted into diabetic mice. Synonyms: HuGLP-1; GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat); Preproglucagon (92-128) (human, bovine, guinea pig, mouse, rat); H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH; L-histidyl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-histidyl-L-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl-glycyl-L-arginyl-glycine. Grades: ≥95%. CAS No. 87805-34-3. Molecular formula: C186H275N51O59. Mole weight: 4169.48. | |
| Glucagon-Like Peptide 1 Receptor Agonist | A nonpeptidic quinoxaline compound that acts as a GLP-1R agonist and an allosteric modulator of GLP-1 binding. Shown to induce GLP-1R-mediated cAMP production in BHK plasma membrane preparations (EC50=101nM) and potentiate glucose-dependent insulin release in pancreatic islets derived from wild-type, but not GLP-1R -/-, mice. Unlike GLP-1, its biological activity is not inhibited by orthosteric antagonists such as Exendin. Group: Biochemicals. Alternative Names: 6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-, 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline (DMB); Compound 2; GLP-1R Agonist. Grades: Highly Purified. CAS No. 281209-71-0. Pack Sizes: 5mg. Molecular Formula: C??H??Cl?N?O?S, Molecular Weight: 348.3. US Biological Life Sciences. |  Worldwide |
| Glucagon-Like Peptide 1 Receptor Agonist II (4- (3- (benzyloxy) phenyl) -2- (ethylsulfinyl) -6- (trifluoromethyl) pyrimidine, Glucagon-Like Peptide 1 Receptor Agonist II, Compound B) | A pyrimidine small molecule that acts as a GLP-1 allosteric agonist that induces cAMP signaling in HEK293 cells expressing the GLP-1 receptor with EC50 = 0.66uM and 99% efficacy (similar data with rat GLP-1 receptor), does not compete with radiolabelled GLP-1 in receptor binding assays, and is not active in cells expressing the GLP-2, GIP, PTH, or glucagon receptors. In rodent islets, insulin secretion increases in a dose-dependent and glucose-dependent manner, either alone or in an additive fashion when combined with the endogenous GLP-1 peptide. In vivo, this molecule exhibits insulinotropic effects when dosed at 10mg/kg in SD rats undergoing an IVGTT and a hyperglycemic clamp. It is also shown to increase insulin secretion in perifusion assays involving normal and diabetic human islets ex vivo, at concentrations between 1 and 10uM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Glucagon-Like Peptide (GLP) II, human | Glucagon-Like Peptide (GLP) II, human, a 33-amino acid Peptide derived from proglucagon C-terminal, is mainly produced by intestinal L cells. GLP II stimulates intestinal mucosal growth and reduces intestinal epithelial cell apoptosis. Synonyms: Glucagon-like peptide 2; H-His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-OH; L-histidyl-L-alanyl-L-alpha-aspartyl-glycyl-L-seryl-L-phenylalanyl-L-seryl-L-alpha-aspartyl-L-alpha-glutamyl-L-methionyl-L-asparagyl-L-threonyl-L-isoleucyl-L-leucyl-L-alpha-aspartyl-L-asparagyl-L-leucyl-L-alanyl-L-alanyl-L-arginyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-asparagyl-L-tryptophyl-L-leucyl-L-isoleucyl-L-glutaminyl-L-threonyl-L-lysyl-L-isoleucyl-L-threonyl-L-aspartic acid; [Ala19]Glucagon-Like Peptide II, rat; GLP-2 (1-33) (human); Glucagon-Like Peptide-2 (1-33). Grades: 95%. CAS No. 89750-15-2. Molecular formula: C165H254N44O55S. Mole weight: 3766.11. | |
| Glucagon-like peptide i fragment 7-36*amide human | Heterocyclic Organic Compound. Alternative Names: PREPROGLUCAGON (98-127) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT;PREPROGLUCAGON 78-107 AMIDE;PREPROGLUCAGON (78-107) AMIDE (HUMAN);PROGLUCAGON (78-107) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT;glucago. CAS No. 107444-51-9. Molecular formula: C149H226N40O45. Mole weight: 3297.67. Appearance: White powder. Purity: 0.96. IUPACName: 9,9-dimethyl-1-(sulfinylamino)decane. Canonical SMILES: CCC (C)C (C (=O)NC (C)C (=O)NC (CC1=CNC2=CC=CC=C21)C (=O)NC (CC (C)C)C (=O)NC (C (C)C)C (=O)NC (CCCCN)C (=O)NCC (=O)NC (CCCNC (=N)N)C (=O)N)NC (=O)C (CC3=CC=CC=C3)NC (=O)C (CCC (=O)O)NC (=O)C (CCCCN)NC (=O)C (C)NC (=O)C (C)NC (=O)C (CCC (=O)N)NC (=O)CNC (=O)C (CCC (=O)O)NC (=O)C (CC (C)C)NC (=O)C (CC4=CC=C (C=C4)O)NC (=O)C (CO)NC (=O)C (CO)NC (=O)C (C (C)C)NC (=O)C (CC (=O)O)NC (=O)C (CO)NC (=O)C (C (C)O)NC (=O)C (CC5=CC=CC=C5)NC (=O)C (C (C)O)NC (=O)CNC (=O)C (CCC (=O)O)NC (=O)C (C)NC (=O)C (CC6=CNC=N6)N. Density: 1.47. Catalog: ACM107444519. |  |
| Glucagon receptor antagonist-2 | Glucagon receptor antagonist-2 is a highly potent glucagon receptor antagonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 202917-18-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-50158. | |
| Glucagon Receptor Antagonist I | Glucagon receptor antagonist I is a potent and competitive antagonist of the glucagon receptor (GCGR) with an IC50 value of 181 nM. Synonyms: GCGR Antagonist I; hGCGR Antagonist; N-[3-cyano-6-(1,1-dimethylpropyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-2-ethyl-butanamide. Grades: ≥99%. CAS No. 438618-32-7. Molecular formula: C20H30N2OS. Mole weight: 346.5. | |
| Glucagon receptor antagonists 1 | Glucagon receptor antagonists-1 is a highly potent glucagon receptor antagonist, which is activated by glucagon and is a member of the class B G-protein coupled family of receptors. Uses: Glucagon receptor antagonist. Synonyms: glucagon receptor antagonists 1; 1-(4-(2-(Benzyloxy)-4-fluorophenyl)-2,6-diisopropyl-5-(prop-1-en-1-yl)pyridin-3-yl)ethanol; 1-[4-(4-fluoro-2-phenylmethoxyphenyl)-2,6-di(propan-2-yl)-5-[(E)-prop-1-enyl]pyridin-3-yl]ethanol. Grades: ≥95%. CAS No. 503559-84-0. Molecular formula: C29H34FNO2. Mole weight: 447.59. | |
| glucagon receptor antagonists-2 | glucagon receptor antagonists-2 is a highly potent antagonist of glucagon receptor. Synonyms: glucagon receptor antagonists 2; (6E)-3-fluoro-6-[3-[(1R)-1-hydroxyethyl]-2,6-di(propan-2-yl)-5-propyl-1H-pyridin-4-ylidene]cyclohexa-2,4-dien-1-one3-Pyridinemethanol, 4-(4-fluoro-2-hydroxyphenyl)-a-methyl-2,6-bis(1-methylethyl)-5-propyl-, (aR)-. CAS No. 202917-18-8. Molecular formula: C22H30FNO2. Mole weight: 359.48. | |
| glucagon receptor antagonists-3 | glucagon receptor antagonists-3 is a highly potent antagonist of glucagon receptor. Synonyms: glucagon receptor antagonists 3; 3-Pyridinemethanol, 4-(4-fluoro-2-hydroxyphenyl)-a-methyl-2,6-bis(1-methylethyl)-5-propyl-, (aR,4R)-rel- (9CI);(aphlaR,4R)-4-(4-Fluoro-2-hydroxyphenyl)-alpha-methyl-2,6-bis(1-methylethyl)-5-propyl-3-pyridinemethanol. CAS No. 202917-17-7. Molecular formula: C22H30FNO2. Mole weight: 359.48. | |
| glucagon receptor antagonists-4 | glucagon receptor antagonists-4 is a potent glucagon receptor antagonist with great oral bioavailability in vivo. Synonyms: PF-06291874; PF 06291874; PF06291874; PF-6291874; PF 6291874; PF6291874; glucagon receptor antagonists 4; β-Alanine, N-[4-[(1S)?-1-[3,?5-dimethyl-4-[4-(trifluoromethyl)?-1H-pyrazol-1-yl]?phenoxy]?butyl]?benzoyl]?-. CAS No. 1393124-08-7. Molecular formula: C26H28F3N3O4. Mole weight: 503.51. | |
| Glucagon (swine) | Glucagon, a peptide compound, is effective in increasing the glucose concentration in bloodstream and could be released by pancreatic α cells. Synonyms: Glucagonum; Glucagone; HG-Factor; His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr; Glucagon-like-immunoreactivity; Glucaton. Grades: 98%. CAS No. 16941-32-5. Molecular formula: C153H225N43O49S. Mole weight: 3482.75. | |
| 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) | 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2; L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-argininamide; 7-36-Glucagon-like peptide 1 (Octodon degus), 8-glycine-36-L-argininamide-; Albiglutide; [Gly8,Arg36]-GLP 1 (7-36) amide (Octodon degus). Grades: ≥95%. CAS No. 224638-84-0. Molecular formula: C148H224N40O45. Mole weight: 3283.61. | |
| 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) TFA | 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) TFA is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2.TFA; L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-argininamide trifluoroacetic acid; 7-36-Glucagon-like peptide 1 (Octodon degus), 8-glycine-36-L-argininamide-, trifluoroacetate; Albiglutide TFA; [Gly8,Arg36]-GLP 1 (7-36) amide (Octodon degus) TFA. Grades: ≥95%. Molecular formula: C150H225F3N40O47. Mole weight: 3397.63. | |
| (Asp28)-Glucagon (1-29) (human, rat, porcine) | (Asp28)-Glucagon (1-29) (human, rat, porcine) is a deamidation product of glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asp-Thr-OH; L-Histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-α-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-α-aspartyl-L-threonine. Grades: ≥95%. CAS No. 1037751-81-7. Molecular formula: C153H224N42O50S. Mole weight: 3483.78. | |
| (Aspartimide15)-Glucagon trifluoroacetate salt | (Aspartimide15)-Glucagon trifluoroacetate salt is an impurity of glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Aspartimide-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH. Molecular formula: C153H223N43O48S.C2HF3O2. Mole weight: 3578.75. | |
| (Aspartimide21)-Glucagon trifluoroacetate salt | (Aspartimide21)-Glucagon trifluoroacetate salt is an impurity of glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Aspartimide-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH. Molecular formula: C153H223N43O48S.C2HF3O2. Mole weight: 3578.75. | |
| (β-Ala29)-Glucagon trifluoroacetate salt | (β-Ala29)-Glucagon trifluoroacetate salt is an impurity of glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-β-Ala-OH. Molecular formula: C152H223N43O48S.C2HF3O2. Mole weight: 3566.74. | |
| Biotinyl-Glucagon (1-29) (human, rat, porcine) | Synonyms: Biotinyl-Glucagon (1-29), human, bovine, porcine; Biotinyl-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH. Grades: ≥95% by HPLC. CAS No. 1802086-28-7. Molecular formula: C163H239N45O51S2. Mole weight: 3709.03. | |
| Dasiglucagon acetate | Dasiglucagon acetate is a glucagon analog for diabetic hypoglycemic treatment, which has a higher absorption rate and longer plasma elimination half-life than conventional reconstituted glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Aib-Ala-Arg-Ala-Glu-Glu-Phe-Val-Lys-Trp-Leu-Glu-Ser-Thr-OH.CH3CO2H; L-histidyl-L-seryl-L-glutaminyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-alpha-methyl-alanyl-L-alanyl-L-arginyl-L-alanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-phenylalanyl-L-valyl-L-lysyl-L-tryptophyl-L-leucyl-L-alpha-glutamyl-L-seryl-L-threonine acetic acid. Grades: ≥95%. Molecular formula: C154H226N38O52. Mole weight: 3441.67. | |
| des-His1-[Glu9]-Glucagon (1-29) amide | A glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes) that displays no agonist activity. It binds to glucagon receptors to stimulate breakdown of inositol phospholipids by phospholipase C. It was shown to potentiate glucose-stimulated pancreatic insulin release in vitro. It blocks added glucagon-induced hyperglycemia in normal rabbits without affecting glycogenolysis in vivo. Also blocks endogenous glucagon-induced hyperglycemia in streptozocin diabetic rats. Synonyms: (Des-His1,Glu9)-Glucagon (1-29) amide (human, rat, porcine); H-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Glu-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2; L-seryl-L-glutaminyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparagyl-L-threoninamide. Grades: ≥95%. CAS No. 110084-95-2. Molecular formula: C148H221N41O47S. Mole weight: 3358.68. | |
| [Des-His1,Glu9]-Glucagon (1-29) amide trifluoroacetate salt | [Des-His1,Glu9]-Glucagon (1-29) amide is a peptide glucagon receptor antagonist (pA2 = 7.25 for glucagon binding to isolated rat liver membranes). It binds to glucagon receptors in a magnesium- and GTP-independent manner to stimulate breakdown of inositol phospholipids by phospholipase C, but has no effect on adenylate cyclase activity, in hepatocytes. In vivo, [Des-His1,Glu9]-glucagon (1-29) amide prevents glucagon-induced hyperglycemia in rabbits and decreases blood glucose in rats with diabetes induced by streptozotocin. Grades: ≥95%. Molecular formula: C148H221N41O47S·xCF3COOH. Mole weight: 3358.65. | |
| (Des-His1)-Glucagon trifluoroacetate salt | (Des-His1)-Glucagon trifluoroacetate salt is an impurity of glucagon. Synonyms: Glucagon (2-29) TFA; H-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH TFA; L-seryl-L-glutaminyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparagyl-L-threonine trifluoroacetate salt. Grades: ≥95%. Molecular formula: C147H218N40O48S.C2HF3O2. Mole weight: 3459.62. | |
| (Des-Thr5)-Glucagon | Synonyms: H-His-Ser-Gln-Gly-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH; L-Histidyl-L-seryl-L-glutaminylglycyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-α-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine. Grades: ≥95%. CAS No. 1802078-27-8. Molecular formula: C149H218N42O47S. Mole weight: 3381.64. | |
| (Des-Thr7)-Glucagon | Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH; L-Histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-α-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine. Grades: ≥95%. CAS No. 1802078-28-9. Molecular formula: C149H218N42O47S. Mole weight: 3381.64. | |
| (Glu20)-Glucagon (1-29) (human, rat, porcine) | (Glu20)-Glucagon (1-29) (human, rat, porcine) is a deamidation product of glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Glu-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH. Grades: ≥95%. CAS No. 2022956-46-1. Molecular formula: C153H224N42O50S. Mole weight: 3483.78. | |
| (Glu24)-Glucagon (1-29) (human, rat, porcine) | (Glu24)-Glucagon (1-29) (human, rat, porcine) is a deamidation product of glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Glu-Trp-Leu-Met-Asn-Thr-OH. Grades: ≥95%. CAS No. 308356-99-2. Molecular formula: C153H224N42O50S. Mole weight: 3483.78. | |
| (Glu3)-Glucagon (1-29) (human, rat, porcine) | (Glu3)-Glucagon (1-29) (human, rat, porcine) is a deamidation product of glucagon. Synonyms: H-His-Ser-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH. Grades: ≥95%. CAS No. 108997-34-8. Molecular formula: C153H224N42O50S. Mole weight: 3483.78. | |
| (Met(O)27)-Glucagon (1-29) (human, rat, porcine) | (Met(O)27)-Glucagon (1-29) (human, rat, porcine) shows the same maximum glucose mobilizing activity as native glucagon in rat liver cells, but its activity is lower. This suggests that methionine plays a crucial role in the binding of glucagon to its liver receptor. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met(O)-Asn-Thr-OH; L-histidyl-L-seryl-L-glutaminyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-S-oxo-L-methionyl-L-asparagyl-L-threonine; 27-Met-sulfoxide-glucagon; glucagon, Met-sulfoxide(27)-; glucagon, methionine sulfoxide(27)-. Grades: ≥95%. CAS No. 75217-63-9. Molecular formula: C153H225N43O50S. Mole weight: 3498.75. | |
| 2-Ethoxypyridin-4-ylboronic Acid | 2-Ethoxypyridin-4-ylboronic Acid is patented as a reagent to prepare spiro-imidazolone derivatives as glucagon receptor antagonists for treatment of diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1072946-58-7. Pack Sizes: 500mg, 1g. Molecular Formula: C7H10BNO3, Molecular Weight: 166.97. US Biological Life Sciences. | Worldwide |
| 4-[4-(4-Fluorophenyl)-2-[4-(methylthio)phenyl]-1H-imidazol-5-yl]pyridine | Potential inhibitor of glucagon receptors, also used in the synthesis of p38 MAP kinase inhibitors. Group: Biochemicals. Alternative Names: 4-[5-(4-Fluorophenyl)-2-[4-(methylthio)phenyl]-1H-imidazol-4-yl]pyridine. Grades: Highly Purified. CAS No. 152121-44-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 4-Bromo-2,6-xylidine | 4-Bromo-2,6-xylidine, is an organic building block used for the synthesis of various pharmaceutical compounds. It can be used for the synthesis of potent glucagon receptor antagonist for the treatment of diabetes mellitus. Group: Biochemicals. Alternative Names: 4-Bromo-2,6-dimethylbenzenamine; 2,6-Dimethyl-4-bromoaniline; 4-Bromo-2,6-dimethylaniline; 4-Bromo-2,6-dimethylbenzenamine; 4-Bromo-2,6-dimethylphenylamine; NSC 227944. Grades: Highly Purified. CAS No. 24596-19-8. Pack Sizes: 10g, 25g. US Biological Life Sciences. | Worldwide |
| 4-Oxocyclohexane carboxylic Acid | 4-Oxocyclohexane carboxylic Acid is used in the preparation of Indomethacin (I641000) analogues used in the treatment of prostate cancer. In addition it is used in the synthesis of β-alanine derivatives as glucagon receptor antagonists. Group: Biochemicals. Alternative Names: 4-Ketocyclohexane carboxylic Acid; 4-Ketocyclohexyl carboxyl ic Acid; 4-Oxo-1-cyclohexanecarboxylic Acid; 4-Oxocyclohexane carboxylic Acid; Cyclohexanone-4-carboxylic Acid. Grades: Highly Purified. CAS No. 874-61-3. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| AC 187 | AC 187 is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels and increases food intake in vivo. Synonyms: Ac-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2; N-acetyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide; AC187; salmon calcitonin (8-32) reduced; acetyl-(Asn30,Tyr32)sCT(8-37); AC-187. Grades: >98%. CAS No. 151804-77-2. Molecular formula: C127H205N37O40. Mole weight: 2890.25. | |
| AC 187 acetate | AC 187 acetate is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels, and increases food intake in vivo. Synonyms: Ac-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2.CH3CO2H; N-acetyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide acetic acid. Grades: ≥95%. Molecular formula: C129H209N37O42. Mole weight: 2950.26. | |
| Ac-Octreotide | Ac-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: Ac-D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); N-Acetyl-Phe-Octreotide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-; N-Acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2?7)-disulfide; D-Phe(Ac)-Octreotide; Ac-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7). Grades: ≥95%. CAS No. 83795-61-3. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28. | |
| Adenosine Receptor Agonist, NECA ( (2S, 3S, 4R, 5R) -5- (6-amino-9H-purin-9-yl) -N-ethyl-3, 4-di hydroxytetra hydrofuran-2-carboxamide ) | A cell-permeable adenosine analog that acts a potent non-selective agonist of adenosine receptors (Ki = 14nM, 20nM, 2.4uM and 6.2nM for A1, A2A, A2B, A3, respectively). Increases intracellular cAMP production (EC50 = 3.1uM in A2B expressing CHO cells). Shown to increase glucagon release in a dose-dependent manner and inhibit insulin release at low concentrations. Although at higher concentration some insulin release is observed. Also, displays a wide range adenosine-dependent effects, such as blocking platelet aggregation and inhibiting DNA synthesis. When administered at reperfusion, it is shown reduce infarction and block the formation of the mitochondrial permeability transition pore by activating p70S6 kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 35920-39-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Adomeglivant | Adomeglivant has been found to be a glucagon receptor antagonist that could probably be effective for both type-I and type-II diabetes mellitus. Synonyms: Adomeglivant; LY-2409021; Adomeglivant [USAN]; UNII-74Z5ZL2KVG; LY2409021; LY 2409021; 3- [ [4- [ (1S) -1- [4- (4-tert-butylphenyl) -3, 5-dimethylphenoxy] -4, 4, 4-trifluorobutyl] benzoyl] amino] propanoic acid. Grades: 98%. CAS No. 1488363-78-5. Molecular formula: C32H36F3NO4. Mole weight: 555.64. | |
| Albiglutide | Albiglutide is a glucagon-like peptide-1 (GLP-1) agonist approved for the treatment of type 2 diabetes. Uses: Incretins; antidiabetic. Synonyms: Eperzan; Tanzeum. CAS No. 782500-75-8. Molecular formula: C3232H5032N864O979S41. Mole weight: 72971.45. | |
| Amylin (IAPP), feline | Amylin (IAPP), feline is a regulatory polypeptide consisting of 37 amino acids that inhibits the secretion of insulin and glucagon. Synonyms: Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Ile-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Ala-Ile-Leu-Ser-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bridge: Cys2-Cys7). Grades: ≥95%. Molecular formula: C165H270N52O54S2. Mole weight: 3910.45. | |
| Amylin (rat) | Amylin (rat), islet Amyloid Polypeptide (IAPP), is a glucoregulatory peptide from rat pancreatic cells. It inhibits glucagon secretion, delays gastric emptying and acts as a satiety agent. It is used to study the regulation of satiety and obesity. It binds to heteromeric complexes of human calcitonin receptor 2 (CTR2) with receptor activity-modifying protein (RAMP) 1 or 3. It also binds to mouse α-thyroid-stimulating hormone thyrotroph (α-TSH) cells and rat nucleus accumbens membrane preparations. It inhibits insulin-induced, but not basal, glycogen synthesis in hepatocytes isolated from fasted rats in vitro. It does not form fibrils and is not cytotoxic unlike human amylin. It is active in vivo. Synonyms: Amylin, amide, rat; Amylin (mouse, rat); IAPP (mouse, rat); Islet amyloid polypeptide (mouse, rat); H-Lys-Cys(1)-Asn-Thr-Ala-Thr-Cys(1)-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2; L-lysyl-L-cysteinyl-L-asparagyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-arginyl-L-seryl-L-seryl-L-asparagyl-L-asparagyl-L-leucyl-glycyl-L-prolyl-L-valyl-L-leucyl-L-prolyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide (2->7)-disulfide. Grades: ≥98%. CAS No. 124447-81-0. Molecular formula: C167H272N52O53S2. Mole weight: 3920.43. | |
| APD597 (JNJ-38431055) | APD597, also known as JNJ-38431055, is a potent and selective GPR119 agonist, which is potential useful for the treatment of type 2 diabetes. GPR119 agonists mediate a unique nutrient-dependent dual elevation of both insulin and glucagon like peptide 1/glucose-dependent insulinotropic peptide levels in vivo. Synonyms: APD597; APD-597; APD 597; JNJ-38431055; JNJ 38431055; JNJ38431055. Grades: 98%. CAS No. 897732-93-3. Molecular formula: C21H29N5O6S. Mole weight: 479.55. | |
| AR 231453 | AR231453 is a potent and selective small molecule agonist of GPR119 that enhances glucose-dependent insulin secretion and glucagon-like peptide 1 (GLP-1) release. It is Antidiabetic agent. Synonyms: AR231453; AR-231453; AR 231453; AR-231,453; AR231,453; AR231,453. Grades: >98%. CAS No. 733750-99-7. Molecular formula: C21H24FN7O5S. Mole weight: 505.52. | |
| Arachidonyl serotonin | Arachidonyl serotonin is a dual target agent of transient receptor potential vanilloid-type I (TRPV1) antagonist and fatty acid amide hydrolase (FAAH) inhibitor, which is responsible for inactivation of anandamide and other endogenous cannabinoids. Its IC50 values are 37-40 nM and 5.6 μM for TRPV1 and FAAH respectively. It inhibits the FAAH activity isolated from mouse neuroblastoma cells with an IC50 value of 12 μM. It is a very tight binding, competitive inhibitor of FAAH. It does not inhibit cPLA2 and is essentially devoid of cannabimimetic activity. It was shown to be present in the ileum and jejunum of the gastrointestinal tract and modulate glucagon-like peptide-1 (GLP-1) secretion. It displays strong analgesic activity against both acute and chronic peripheral pain in rodents. Synonyms: AA-5HT; AA5HT; AA 5HT; N-arachidonoyl-serotonin; Arachidonoyl serotonin; N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide; AA-5HT; AA5HT; N-arachidonoyl-serotonin; N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-eicosatetraenamide; (5Z,8Z,11Z,14Z)-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)icosa-5,8,11,14-tetraenamide. CAS No. 187947-37-1. Molecular formula: C30H42N2O2. Mole weight: 462.67. | |
| BAY-27-9955 | BAY-27-9955 is a specific glucagon receptor antagonist. Synonyms: 1-[2-(4-fluorophenyl)-4,6-di(propan-2-yl)-3-propylphenyl]ethanol; BAY-27-9955; BAY-27-9955; BAY-27-9955; BAY-279955; BAY-279955; BAY-279955; (+)-3,5-diisopropyl-2-(1-hydroxyethyl)-6-propyl-4'-fluoro-1,1'-biphenyl. Grades: >98%. CAS No. 202855-56-9. Molecular formula: C23H31FO. Mole weight: 342.49. | |
| Beinaglutide | Beinaglutide is a recombinant human GLP-1 (rhGLP-1) approved as a novel drug for diabetes treatment. Beinaglutide also has promising effect on obesity. Synonyms: Benaglutide; Glucagon like peptide-i (7-36); BEM-014; H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-OH. CAS No. 123475-27-4. Molecular formula: C149H225N39O46. Mole weight: 3298.61. | |
| BETP | BETP is a positive allosteric modulator and partial agonist of the glucagon-like peptide 1 (GLP-1) receptor, displaying no effect on GLP-2, GIP, PTH or glucagon receptors. BETP promotes oxyntomodulin binding to GLP-1 receptor. It potentiates oxyntomodulin-mediated GLP-1 receptor signaling in vitro and insulin secretion in vivo. Synonyms: 2-(Ethylsulfinyl)-4-[3-(phenylmethoxy)phenyl]-6-(trifluoromethyl)pyrimidine. Grades: ≥98% by HPLC. CAS No. 1371569-69-5. Molecular formula: C20H17F3N2O2S. Mole weight: 406.42. | |
| Boc5 | Boc5, a non-peptide glucagon-like peptide-1 (GLP-1R) receptor agonist. Synonyms: 1,3-Bis[[4-(Tert-Butoxy-Carbonylamino)Benzoyl]Amino]-2,4-Bis[3-Methoxy-4-(Thiophene-2-Carbonyloxy)-Phenyl]Cyclobutane-1,3-Dicarboxylic Acid. Grades: ≥98% by HPLC. CAS No. 917569-14-3. Molecular formula: C54H52N4O16S2. Mole weight: 1077.1. | |
| Bofanglutide | Bofanglutide (GZR18) is an analog of glucagon-like peptide-1 (GLP-1), which exhibits agonistic activity for GLP-1 receptor , with an EC 50 of 0.677 nM. GZR18 ameliorates type 2 diabetes [1]. Uses: Scientific research. Group: Peptides. Alternative Names: GZR18. CAS No. 2668298-70-0. Pack Sizes: 1 mg. Product ID: HY-P10269. | |
| BPI-3016 | BPI-3016 is an analogue of human glucagon-like peptide 1 (hGLP-1) that has a long effect on type 2 diabetes mellitus. In vitro, BPI-3016 exhibited an affinity to GLP receptors and promotes cAMP production. In vivo, the half-life of BPI-3016 was 95h after single dosing in pharmacokinetic studies in diabetic cynomolgus monkey models. Uses: The treatment of type 2 diabetes. Synonyms: BPI-3016; BPI 3016; BPI3016. | |
| Cotadutide | Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC 50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D) [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: MEDI0382. CAS No. 1686108-82-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2231. | |
| Cotadutide | Cotadutide (MEDI 0382) is a subcutaneous GLP-1 and glucagon receptor dual agonist that can be used to treat type 2 diabetes. Synonyms: MEDI 0382. CAS No. 1686108-82-6. Molecular formula: C167H252N42O55. Mole weight: 3728.03. | |
| Cyclamic acid | Cyclamic acid (Cyclamate) is a commonly used sweetener. Cyclamic acid sodium is toxic to osteoblasts and can inhibit cell proliferation, induce apoptosis and reduce cell mineralization. Cyclamic acid sodium causes focal necrosis of bladder organs in rats in vitro, which can promote bladder cancer, but some studies have shown that low doses of Cyclamic acid sodium have no carcinogenic effect. In addition, Cyclamic acid sodium has no effect on insulin and glucagon secretion induced by arginine [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cyclohexylsulfamic acid; Cyclamate. CAS No. 100-88-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0541. | |
| Cyclosomatostatin | Cyclosomatostatin is a non-selective somatostatin (sst) receptor antagonist. It blocks the effects of CRF-induced suppression of gastric empyting and sst on airway β-adrenergic function. It also prevents growth hormone, insulin, glucagon release and modulation of ACh release. It acts as a sst receptor agonist in human neuroblastoma cell line SH-SY5Y. Uses: Hormone antagonists. Synonyms: Cyclo(7-aminoheptanonyl-Phe-D-Trp-Lys-Thr[Bzl]); Cyclo[7-aminoheptanoyl-L-phenylalanyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-L-threonyl]. CAS No. 84211-54-1. Molecular formula: C44H57N7O6. Mole weight: 779.98. | |
| D-allo-Thr(6)-Octreotide | D-allo-Thr(6)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-allo-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); D-Phe-Cys-Phe-D-Trp-Lys-D-allo-Thr-Cys-Thr-ol (Disulfide Bridge between Cys2-Cys7); Octreotide EP impurity-A; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-allo-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide. CAS No. 1546983-12-3. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25. | |
| Danuglipron | Danuglipron (PF-06882961) is an orally active glucagon-like peptide-1 receptor (GLP-1R) agonist. Danuglipron has the potential for type 2 diabetes research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-06882961. CAS No. 2230198-02-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125824. | |
| Danuglipron free base | Danuglipron, also known as PF-06882961 is a potent, orally bioavailable agonist of the glucagon-like peptide-1 receptor agonist (GLP-1R). WO 2019148044 (2019). Group: Agonists. Alternative Names: Danuglipron; PF-06882961; PF 06882961; PF06882961; Danuglipron free base. CAS No. 2230198-02-2. Molecular formula: C31H30FN5O4. Mole weight: 555.61. Appearance: Solid powder. Purity: >98%. IUPACName: (S)-2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl)piperidin-1-yl)methyl)-1-(oxetan-2-ylmethyl)-1H-benzo[d]imidazole-6-carboxylic acid. Canonical SMILES: OC (C1=CC=C (N=C (CN2CCC (C3=NC (OCC4=CC=C (C#N) C=C4F) =CC=C3) CC2) N5C[C@H]6OCC6) C5=C1) =O. Catalog: ACM2230198022. | |
| Dapiglutide | Dapiglutide (ZP7570) is a long-acting glucagon-like peptide-1 receptor 1R (GLP-1R)/Glucagon-like peptide-2 receptor (GLP-2R) dual agonist. Dapiglutide alleviates intestinal dysfunction in a mouse short bowel model and has anti-obesity effects [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: ZP7570. CAS No. 2296814-85-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3291. | |
| D-Cys(2)-Octreotide | D-Cys(2)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-D-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide Impurity-6; H-D-Phe-D-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2?7)-disulfide; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide. CAS No. 108102-47-2. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25. | |
| D-Cys(7)-Octreotide | D-Cys(7)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-D-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide. CAS No. 1211530-36-7. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25. | |
| Des-D-Phe(1)-Octreotide | Des-D-Phe(1)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys1-Cys6); Octreotide Impurity-F; H-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys1-Cys6); L-Cysteinamide, L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (1?6)-disulfide. Molecular formula: C40H57N9O9S2. Mole weight: 872.07. | |
| Des-D-Trp(4)-Octreotide | Des-D-Trp(4)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys6); Octreotide Impurity-G; H-D-Phe-Cys-Phe-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys6); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?6)-disulfide. Molecular formula: C38H56N8O9S2. Mole weight: 833.03. | |
| Des-Glu(3)-Semaglutide | Des-Glu(3)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: L-Histidyl-2-methylalanylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-His-Aib-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Des-Glu(9)-Semaglutide. Molecular formula: C182H284N44O56. Mole weight: 3984.53. | |
| Des-Lys(5)-Octreotide | Des-Lys(5)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys6); Octreotide Impurity-H; H-D-Phe-Cys-Phe-D-Trp-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys6); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?6)-disulfide. Molecular formula: C43H54N8O9S2. Mole weight: 891.07. | |
| Des-Threoninol-Octreotide | Des-Threoninol-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystine (Disulfide Bridge between Cys2-Cys7); Octreotide impurity-11; H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-OH (Disulfide bridge: Cys2-Cys7); L-Cysteine, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-, cyclic (2?7)-disulfide; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteine cyclic (2?7)-disulfide. CAS No. 160841-00-9. Molecular formula: C45H57N9O9S2. Mole weight: 932.13. | |
| Dimethyl DL-glutamate hydrochloride | Dimethyl DL-glutamate is a cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes. It also potentiates the insulinotropic potential of glyburide and glucagon-like peptide Dimethyl DL-glutamate is used as a cell-permeable form of glutamate in studies of glutamate action in β-cells. Synonyms: Glutamic acid dimethyl ester; Dimethyl 2-aminopentanedioate; Dimethyl 2-aminopentanedioate hydrochloride; H-DL-Glu(OMe)-OMe.HCl; H-DL-Glu(Ome)-Ome. Grades: ≥ 98% (HPLC). CAS No. 13515-99-6. Molecular formula: C7H13NO4·HCl. Mole weight: 211.6. | |
| Dipeptidyl peptidase IV | Dipeptidyl peptidase IV (DPP-IV) is a protease that inactivates insulin stimulating hormones such as glucagon-like peptide 1 (GLP-1) and glucose-dependent insulin-like polypeptide (GIP). Dipeptidyl peptidase IV can be used as a binding protein and ligand for various extracellular molecules. Dipeptidyl peptidase IV can be used in diabetes research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DPP-IV. CAS No. 54249-88-6. Pack Sizes: 10 mU. Product ID: HY-E70397. | |
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