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| Product | Description | |
|---|---|---|
| Clear Glue, 1 gal | Notes: This multipurpose school glue goes on clear and dries clear for perfect projects every time. Safe, nontoxic, and washable. Storage Code: Green; general chemical storage. Product ID: 865445. -- SOLD FOR EDUCATIONAL USE ONLY -- |  |
| Hot Melt Glue | Hot Melt Glue. Group: Polymers. |  |
| Ti3C2 MXene glue | Ti3C2 MXene glue. Uses: Flexible electronic devices (sensors, capacitors), flexible batteries, etc. it can be used to deposit and load other materials to make composite materials and separation membranes for seawater separation. Group: Mxenes materials. CAS No. 12363-89-2. | |
| White Glue, 1 gal | Storage Code: Green; general chemical storage. Notes: Multi-purpose glue for school or office; effective on wood, paper, fabric, leather, ceramics, and other surfaces. Product ID: 865442. -- SOLD FOR EDUCATIONAL USE ONLY -- | |
| 2-Chloroacetamide | 2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79-07-2. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-W010629. |  |
| 3-Aminopropyltriethoxysilane | 3-Aminopropyltriethoxysilane (APTES) acts as a strong glue to immobilize biomolecules such as antibodies and enzymes to silicon and silicon derivatives such as silicon nitride (Si 3 N 4 )) on. 3-Aminopropyltriethoxysilane also acts as a spacer, providing biomolecules with more spatial freedom during immobilization for higher specific activity. 3-Aminopropyltriethoxysilane can form a more stable, sensitive, and highly biocompatible bioanalytical platform by immobilizing biomolecules onto some solid materials, electrode materials, nanomaterials, and nanocomposites [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: γ-Aminopropyltriethoxysilane; APTES. CAS No. 919-30-2. Pack Sizes: 10 g; 50 g; 100 g. Product ID: HY-D0175. | |
| 3-Methyl-1-butanethiol | colourless liquid with odour of onion or glue. Group: Self-assembly materials. CAS No. 541-31-1. Product ID: 3-methylbutane-1-thiol. Molecular formula: 104.22g/mol. Mole weight: C5H12S. CC(C)CCS. InChI=1S/C5H12S/c1-5(2)3-4-6/h5-6H, 3-4H2, 1-2H3. GIJGXNFNUUFEGH-UHFFFAOYSA-N. | |
| ALV2 | ALV2 is a potent and selective Helios molecular glue degrader. ALV2 binds CRBN, with an IC 50 of 0.57 μM. Helios is the zinc-finger transcription factor that can maintain a stable T reg cell phenotype in the inflammatory tumor microenvironment [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2438124-95-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137206. | |
| CDK2 degrader 1 | CDK2 degrader 1 (Compound 3) is a selective CDK2 molecular glue degrader with a Dmax (CDK2) of > 80% and a Ki (CRBN) > 1 ?M. CDK2 degrader 1 binds to cereblon to induce ubiquitination and subsequent proteasomal degradation of the CDK2. CDK2 degrader 1 is used in the research of a wide range of cancers[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3036604-59-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-163814. | |
| Cemsidomide | Cemsidomide (CFT7455) is a ubiquitin ligase pathway Ikaros / Aiolos degrader with molecular glue activity [1]. Cemsidomide has a GI 50 of 0.05 nM for NCIH929.1 cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CFT7455. CAS No. 2504235-67-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144841. | |
| C.I. Acid blue 72 | C.I. Acid blue 72. Uses: It is used for dyeing silk and acrylic, and can also be used for direct dyeing and discharge printing of leather, paper, hemp and glue. it can also be used as a colorant for paints and inks. Group: Dyes (technical grade). Alternative Names: Acid Blue EGL. CAS No. 12219-17-9. Catalog: AP12219179. |  |
| CR8 | CR8 is a potent and selective inhibitor of CDK. CR8 is a more potent pyridyl analogue of roscovitine. In comparison to roscovirtine, the compound gains in potency toward CK1, which is involved in amyloid-β formation. The R-CR8 enantiomer is slightly more potent than S. CR8 is around 30 times more potent at cellular assay then roscovitine. (R)?-CR8 induces apoptosis and has neuroprotective effect. (R)-CR8 acts as a molecular glue degrader that depletes cyclin K. Synonyms: (R)-CR8; CR 8; CR-8. Grades: 98%. CAS No. 294646-77-8. Molecular formula: C24H29N7O. Mole weight: 431.544. |  |
| DEG-77 | DEG-77, is a IKZF2 and CK1? targeted molecular glue, with DC50s of 15.3 nM and 10 nM, respectively. DEG-77 possesses suitable pharmacokinetic properties, solubility, and selectivity for in vivo studies (t1/2=8h). DEG-77 can be used for acute myeloid leukemia (AML) study[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3032265-06-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157334. | |
| Dextrin | Dextrin is used as a thickening agent in pharmaceuticals, water-soluble glue in envelope adhesives and crispness enhancers in food processing. CAS No. 9004-53-9. Molecular formula: (C6H12O6)x. | |
| Direct Blue 86 | Direct Blue 86 (Solvent Blue 38) is a myelin-sheath stain , commonly utilized in microscopy to detect demyelination in the central nervous system. Direct Blue 86 also is a dye with various applications including as a commercial dye in the printing of cotton and mucilage glue fabrics [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Solvent Blue 38. CAS No. 1330-38-7. Pack Sizes: 100 mg; 500 mg. Product ID: HY-D0953. | |
| dWIZ-1 | dWIZ-1 is a potent WIZ molecular glue degrader. dWIZ-1 recruitments WIZ(ZF7) to cereblon (CRBN) induces WIZ degradation. dWIZ-1 has the potential for the research of sickle cell disease (SCD)[1]. Uses: Scientific research. Group: Signaling pathways. Product ID: HY-159098. | |
| Eragidomide | Eragidomide (CC-90009) is a first-in-class GSPT1-selective cereblon (CRBN) E3 ligase modulator, acts as a molecular glue. Eragidomide coopts the CRL4CRBN to selectively target GSPT1 for ubiquitination and proteasomal degradation[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-90009. CAS No. 1860875-51-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-130800. | |
| Europium atomic absorption standard solution | Europium atomic absorption standard solution. Uses: There are only a few commercial uses for europium. europium oxide, (eu2o3), a compoundof europium, is added to infra-sensitive phosphors to enhance the red colors on tvand computer-monitor picture tubes. it is also added to fluorescent light tubes to increasetheir efficiency, as well as to some materials to make lasers. since it is a good neutron absorber,it is part of nuclear reactor control rods. europium is an additive to the glue used on postagestamps, thus making it possible for the electronic sorting machines in u.s. postal offices to"read" the stamps. Group: Reference-calibration standards. | |
| FPFT-2216 | FPFT-2216, a molecular glue compound, degrades phosphodiesterase 6D (PDE6D), zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3), and casein kinase 1? (CK1?). FPFT-2216 can be used for the research of cancer and inflammatory disease[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2367619-87-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145319. | |
| HbF inducer 2 | HbF inducer 3 (Compound dWIZ-2) is an orally active molecular glue, which degrades the WIZ transcription factor (DC50=13 nM in primary human erythroid precursor cell) and induces the expression of fetal hemoglobin (HbF) (EC50=100 nM). HbF inducer 3 exhibits good pharmacokinetic characteristics in cynomolgus monkeys[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2654011-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159099. | |
| Hexanes, mixed isomers | Hexanes, mixed isomers. Uses: The laboratory uses hexane mixed isomers to extract oil and grease contaminants from water and soil for analysis. as a non-polar solvent, it is used in chromatography. it plays an important role in the preparation of glue for footwear, leather goods and roofing. it is also used in reactions involving strong bases, such as the preparation of grignard reagents. also involved in the preparation of organolithium compound, butyllithium. Additional or Alternative Names: Isohexane, 2-Methyl pentane, iso-Hexane. Product Category: Solvents. CAS No. 92112-69-1. Molecular formula: C6H14. Mole weight: 86.18. IUPACName: hexane. Canonical SMILES: CCCCCC. Density: 0.675 g/cm3. ECNumber: 295-570-2. Product ID: ACM92112691-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| HQ461 | HQ461 is a Molecular-glue degrader. HQ461 acts by promoting an interaction between CDK12 and DDB1-CUL4-RBX1 E3 ubiquitin ligase, leading to polyubiquitination and degradation of CDK12-interacting protein Cyclin K (CCNK). Degradation of CCNK mediated by HQ461 compromised CDK12 function, leading to reduced phosphorylation of a CDK12 substrate, downregulation of DNA damage response genes, and cell death. Structure-activity relationship analysis of HQ461 revealed the importance of a 5-methylthiazol-2-amine pharmacophore and resulted in an HQ461 derivate with improved potency. Uses: Designed for use in research and industrial production. Additional or Alternative Names: HQ461; HQ-461; HQ 461. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1226443-41-9. Molecular formula: C15H15N5OS2. Mole weight: 345.44. Purity: >98%. IUPACName: 2-(2-((6-methylpyridin-2-yl)amino)thiazol-4-yl)-N-(5-methylthiazol-2-yl)acetamide. Canonical SMILES: CC1C=CC=C(NC2=NC(CC(=O)NC3=NC=C(C)S3)=CS2)N=1. Product ID: ACM1226443419. Alfa Chemistry ISO 9001:2015 Certified. Categories: HQ-6. | |
| HQ461 | HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation. HQ461-mediated degradation of cyclin K impairs CDK12 function, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226443-41-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144981. | |
| Indisulam | Indisulam is a carbonic anhydrase inibitor. It is a molecular glue that degrades mRNA splicing factor RBM39. Uses: Antineoplastic agents. Synonyms: E7070; E 7070; E-7070; ER35744; ER 35744; ER-35744; D04522; Indisulam. Grades: ≥98% (HPLC). CAS No. 165668-41-7. Molecular formula: C14H12ClN3O4S2. Mole weight: 385.84. | |
| Isoamyl Mercaptan | colourless liquid with odour of onion or glue. Group: Self assembly and contact printing materials. CAS No. 541-31-1. Product ID: 3-methylbutane-1-thiol. Molecular formula: 104.22g/mol. Mole weight: C5H12S. CC(C)CCS. InChI=1S/C5H12S/c1-5(2)3-4-6/h5-6H, 3-4H2, 1-2H3. GIJGXNFNUUFEGH-UHFFFAOYSA-N. | |
| Keratinase, Recombinant | Keratinase is a particular class of extracellular proteolytic inducible enzyme with the capability of degrading insoluble keratin substrates. It is important for hydrolyzing hair, feather, and collagen in sewage system during waste water treatment. It is also useful in food industry, animal feed preparation etc. Insoluble feather keratin from poultry industry may be converted by enzymatic hydrolysis to glues, feedstuffs, fertilizers, films or used for the production of rare amino acids serine, cysteine and proline. Applications: Keratinase was used for enzymatic treatment of elementary body (eb), gag molecules, and cells in the study of the role glycosaminoglycans (gags) in the invasion of host cells by chlamydia pneumoniae strains. Group: Enzymes. Synonyms: Keratinase; KerA; Keratinase from Bacillus licheniformis; Keratinolytic protease; EC 3.4.21. Enzyme Commission Number: EC 3.4.21. Keratinase. Mole weight: ~39 kDa. Activity: 300 - 1000 units/mg. Storage: Store at -20°C. Form: Lyophilized powder. Source: E. coli BL21. Keratinase; KerA; Keratinase from Bacillus licheniformis; Keratinolytic protease; EC 3.4.21. Cat No: NATE-0853. |  |
| KT-333 | KT-333 is a molecular glues that degrades STAT3 protein. KT-333 mediates the selective degradation of STAT3 through the ubiquitin-proteasome system by binding to STAT3 protein and E3 ubiquitin ligase von Hippel-Lindau protein (VHL). KT-333 has strong selectivity for STAT3 protein degradation and good antitumor activity. KT-333 can be used in the study of hematologic malignancies such as large granular lymphocytic leukemia (LGL-L), peripheral T-cell lymphoma (PTCL), and cutaneous T-cell lymphoma (CTCL) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2502186-79-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-156730. | |
| Lenalidomide | Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-5013. CAS No. 191732-72-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-A0003. | |
| Lenalidomide hemihydrate | Lenalidomide hemihydrate (CC-5013 hemihydrate), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hemihydrate is an orally active immunomodulator. Lenalidomide hemihydrate (CC-5013 hemihydrate) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate (CC-5013 hemihydrate) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-5013 hemihydrate. CAS No. 847871-99-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-A0003B. | |
| Lenalidomide (Standard) | Lenalidomide (Standard) is the analytical standard of Lenalidomide. This product is intended for research and analytical applications. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191732-72-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0003R. | |
| MC-VC-PABC-amide-PEG1-CH2-CC-885 | MC-VC-PABC-amide-PEG1-CH2-CC-885 (compound I-1) is a neoDegrader-Linker conjugate, consists of the GSPT1 degrader/molecular glue CC-885 (HY-101488) and a linker. MC-VC-PABC-amide-PEG1-CH2-CC-885 can be conjugated to the antibody DAR3.7 that specifically targets CD56 to synthesize Antibody-Drug Conjugates (ADCs)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2722697-82-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145448. | |
| Mezigdomide | Mezigdomide (CC-92480), a cereblon E3 ubiquitin ligase modulating agent (CELMoD), acts as a molecular glue. Mezigdomide shows high affinity to cereblon, resulting in potent antimyeloma activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-92480. CAS No. 2259648-80-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129395. | |
| MYC degrader 1 | MYC degrader 1 (compound A80.2HCl) is an orally available MYC molecular glues degrader with anti-tumor activity. MYC degrader 1 restores pRB1 protein activity and re-establishes sensitivity of MYC overexpressing cancer cells to CDK4/6 inhibitors[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2946670-96-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-162318. | |
| Native Bacillus licheniformis Keratinase (feed grade) | Keratinase is a particular class of extracellular proteolytic inducible enzyme with the capability of degrading insoluble keratin substrates. It is important for hydrolyzing hair, feather, and collagen in sewage system during waste water treatment. It is also useful in food industry, animal feed preparation etc. Insoluble feather keratin from poultry industry may be converted by enzymatic hydrolysis to glues, feedstuffs, fertilizers, films or used for the production of rare amino acids serine, cysteine and proline. Group: Enzymes. Synonyms: KerA; Keratinolytic protease; EC 3.4.21. Enzyme Commission Number: EC 3.4.21. Keratinase. Form: Powder. Source: Bacillus licheniformis. Keratinase; KerA; Keratinase from Bacillus licheniformis; Keratinolytic protease; EC 3.4.21. Cat No: FEED-0001. | |
| NST-628 | NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation. NST-628 also binds RAF and prevents the formation of BRAF-CRAF and BRAF-ARAF heterodimers, effectively inhibiting the RAS-MAPK pathway. NST-628 inhibits RAS- and RAF-driven cancers and demonstrated potent inhibition in mutant KRAS, NRAS, BRAF class II/III, and NF1-mutant tumors[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3002056-30-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-158115. | |
| NVP-DKY709 | NVP-DKY709 is an orally active and selective IKZF2 molecular glue degrader with the Dmax and DC50 of 53% and 4 nM, respectively. In addition, NVP-DKY709 can degrade IKZF4 (DC50: 13 nM) and SALL4 (DC50: 2 nM). NVP-DKY709 exerts anti-tumor activity by binding with CRBN to change conformation and recruit and degrade IKZF2[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2291360-73-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-144998. | |
| PLX-3618 | PLX-3618 is a molecular glue, that degrades BRD4 with DC50 of 12.2 nM. PLX-3618 promotes polyubiquitination and subsequent proteasomal degradation of BRD4 by recruiting of the E3 ligase substrate receptor, DCAF11. PLX-3618 inhibits the proliferation of various cancer cells, induces apoptosis in AML cells. PLX-3618 exhibits antitumor activity against AML in mouse models[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2851986-76-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161779. | |
| Pomalidomide | Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-4047. CAS No. 19171-19-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-10984. | |
| Propolis Extract | Propolis Extract. Group: Others. Purity: Flavonoids 12%, 30%. Appearance: Brown powder. Source: Propolis or bee glue is a resinous mixture that honey bees collect from tree buds, sap flows, or other botanical sources. Propolis Extract. Cat No: EXTC-125. | |
| (R)-CR8 | Molecular glue; brings about ubiquination and degradation of cyclin K. Synonyms: (R)-CR8; (R)-CR-8; (R)-CR 8; CR8; CR-8; CR 8; CR8 CDK inhibitor; CR8 CDK inhibitor HCl; CR8 CDK inhibitor hydrochloride; (R)-CR8 trihydrochloride. Grades: ≥99% (HPLC). CAS No. 1786438-30-9. Molecular formula: C24H29N7O.3HCl. Mole weight: 540.92. | |
| (R)-CR8 | (R)-CR8, a second-generation analog of Roscovitine, is a potent CDK1/2/5/7/9 inhibitor. (R)-CR8 inhibits CDK1/cyclin B (IC50=0.09 ?M), CDK2/cyclin A (0.072 ?M), CDK2/cyclin E (0.041 ?M), CDK5/p25 (0.11 ?M), CDK7/cyclin H (1.1 ?M), CDK9/cyclin T (0.18 ?M) and CK1?/? (0.4 ?M). (R)-CR8 induces apoptosis and has neuroprotective effect[1][2]. (R)-CR8 acts as a molecular glue degrader that depletes cyclin K[3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CR8, (R)-Isomer. CAS No. 294646-77-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18340. (R)?-?CR8 | |
| Schisandrin C | Schisandrin C (Schizandrin-C) is a phytochemical lignan isolated from Schizandra chinensis. Schisandrin C has diverse biological activities, including anticancer, anti-inflammatory and antioxidant effects. Schisandrin C is a molecular glue. Schisandrin C can be used for cancer, alzheimer's disease, and liver diseases research. Schisandrin C induces cell apoptosis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cycloocta(1,2-f:3,4-f)bis(1,3)benzodioxole6,7,8,9-tetrahydro-1,13-dimethoxy-7. Product Category: Inhibitors. Appearance: Powder. CAS No. 61301-33-5. Molecular formula: C22H24O6. Mole weight: 384.42. Purity: 0.98. IUPACName: 3,22-Dimethoxy-12,13-dimethyl-5,7,18,20-tetraoxapentacyclo[13.7.0.02,10.04,8.017,21]docosa-1(22),2,4(8),9,15,17(21)-hexaene. Canonical SMILES: CC1CC2=CC3=C(C(=C2C4=C(C5=C(C=C4CC1C)OCO5)OC)OC)OCO3. Density: 1.232 g/ml. Product ID: ACM61301335. Alfa Chemistry ISO 9001:2015 Certified. | |
| SJ3149 | SJ3149 is a selective and potent molecular glue degrader of CK1? protein with broad antiproliferative activity. SJ3149 can be used in cancer research[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026986-17-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-160444. | |
| SJ6986 | SJ6986 is a potent, selective and orally active GSPT1/2 Molecular Glue degrader, with a DC50 of 2.1 nM (Dmax 99%) for GSPT1[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2765625-93-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132199. | |
| Thalidomide | Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a K d of ?250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide can work as molecular glue to potentiate substrate. Uses: Scientific research. Group: Signaling pathways. CAS No. 50-35-1. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-14658. | |
| Urea formaldehyde | Slow-release nitrogen fertilizer for turf grass. Urea formaldehyde is a textile-finish resin of formaldehyde type for treatment of e.g., cotton and rayon materials; in wood-glue industry. Group: Polymers. CAS No. 9011-5-6. Pack Sizes: 25 kg/DRUMS. Product ID: formaldehyde; urea. Molecular formula: 90.08g/mol. Mole weight: C2H6N2O2. C=O.C(=O)(N)N. InChI=1S/CH4N2O.CH2O/c2-1(3)4; 1-2/h(H4, 2, 3, 4); 1H2. ODGAOXROABLFNM-UHFFFAOYSA-N. | |
| VAV1 degrader-3 | VAV1 degrader-3 (Example 185) is an orally active VAV1 molecular glue degrader (DC50: 7 nM). VAV1 degrader-3 reduces immune cell activation, immune cell proliferation and the production of various cytokines. VAV1 degrader-3 can be used for research of inflammatory or autoimmune disorder. VAV1 degrader-3 inhibits disease progression in experimntal autoimmune encephalomyelitis (EAE) mouse model, Collagen-induced arthritis (CIA) mouse model, etc.[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3050683-38-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-168625. | |
| WBC100 | WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc molecule glue degrader. WBC100 is a c-Myc degrader and targets ubiquitin E3 ligase CHIP mediated 26S proteasome pathway. WBC100 is used for c-Myc overexpressing tumors research[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 14-D-Valine-TPL. CAS No. 2095780-08-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145898. | |
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