Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| 1-(2,6-Difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxypyridazine-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione | 1-(2,6-Difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxypyridazine-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione is an impurity of Relugolix, which is an orally administered gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of several hormone-responsive conditions, including uterine fibroids, advanced prostate cancer, and endometriosis. Synonyms: Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-6-(4-nitrophenyl)-; 1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; Relugolix Impurity 9. Grade: ≥95%. CAS No. 1589503-96-7. Molecular formula: C27H22F2N6O5S. Mole weight: 580.56. |  |
| 2-[ (Methylamino) methyl]pyridine | 2-[ (Methylamino) methyl]pyridine is used as a reagent in the preparation and structure activity relationship of imidazolopyrimidones as gonadotropin-releasing hormone (GnRH) receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 21035-59-6. Pack Sizes: 500mg, 1g. Molecular Formula: C7H10N2, Molecular Weight: 122.17. US Biological Life Sciences. |  Worldwide |
| [5-Phenylalanine]-LH-RH Acetate Hydrate (1:x:x) | It is a gonadotropin-releasing hormone (GnRH) analog. Synonyms: [5-Phenylalanine]-luteinizing hormone releasing hormone, acetate (salt), hydrate (1:x:x); [Phe5]-LH-RH, acetate (salt), hydrate (1:x:x); Phe5-LH-releasing hormone, acetate (salt), hydrate (1:x:x); Luteinizing hormone-releasing factor (swine), 5-L-phenylalanine-, acetate (salt), hydrate; Luteinizing hormone-releasing factor (pig), 5-L-phenylalanine-, acetate (salt), hydrate (1:x:x). CAS No. 78308-49-3. Molecular formula: C55H75N17O12.xC2H4O2.xH2O. Mole weight: 1166.31 (free base). | |
| Abarelix | Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Synonyms: Plenaxis, PPI-149; PPI 149; PPI149; R-3827; R 3827; R3827. Grade: 98%. CAS No. 183552-38-7. Molecular formula: C72H95ClN14O14. Mole weight: 1416.09. | |
| Alarelin | Alarelin is a synthetic analog of Gonadotropin-releasing hormone (GnRH) used primarily for its effects on the reproductive system. It acts as a GnRH agonist, initially stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. Alarelin is used in the treatment of conditions such as endometriosis, uterine fibroids, and prostate cancer, as well as in assisted reproductive technologies. Synonyms: 1-9-Luteinizing hormone-releasing factor (swine), 6-D-alanine-9-(N-ethyl-L-prolinamide)-; Luteinizing hormone-releasing factor (pig), 6-D-alanine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-; AY 25205; Dalarelin; Dalareline; L 4513; LHRH-A2; LRH-A2; Luteinizing hormone-releasing hormone analog 2; Surfagon; TAP 127; Wy 18481; H-Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline ethylamide; (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH; Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt; LHRH-A; 6-D-Ala-10-D-gly-LHRH-ethylamide; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline ethylamide. Grade: 95%. CAS No. 52435-06-0. Molecular formula: C56H78N16O12. Mole weight: 1167.32. | |
| [betaAla-D-Cit]-Cetrorelix | An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-beta-Ala-DCit-Leu-Arg-Pro-DAla-NH2; [β-Ala-D-Cit]-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-β-Ala-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-beta-alanyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; betaAla-DCit-Cetrorelix; betaAla-D-Cit-Cetrorelix. Grade: ≥95%. Molecular formula: C73H97ClN18O15. Mole weight: 1502.14. | |
| [betaAla-Leu]-Cetrorelix | An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-beta-Ala-Leu-Arg-Pro-DAla-NH2; [β-Ala-Leu]-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-β-Ala-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-beta-alanyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; betaAla-Leu-Cetrorelix. Grade: ≥95%. Molecular formula: C73H97ClN18O15. Mole weight: 1502.14. | |
| Cetrorelix Acetate | Cetrorelix Acetate is the acetate salt of cetrorelix, which is a potent and synthetic peptide antagonist of gonadotropin-releasing hormone (GnRH) receptor antagonist with IC50 value of 1.21 nM. It binds to radioligand murine LTK- cells with Kd value of 0.2 nM. It inhibits the activation of hGnRHR and a downstream luciferase reporter gene in murine LTK- cells by the GnRHR agonist [D-Trp6]GnRH. It suppresses production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland. It prevents ovulation during in vitro fertilization. It causes prepubertal reduction in bone density, bone strength and bone modeling. It was used as a therapeutic agent for the treatment of blood cancers such as multiple myeloma (MM). It is also used to treat hormone-sensitive cancers of the breast and prostate. It also has antidepressant and anxiolytic activity in vivo. Uses: Fertility agents, female. Synonyms: D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (1:x); D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (salt); Cetrotid; C. Grade: >98%. CAS No. 145672-81-7. Molecular formula: C70H92ClN17O14.xC2H4O2. Mole weight: 1431.06 (free base) | |
| Cetrorelix Acetate | Cetrorelix Acetate (SB-75 acetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC 50 of 1.21 nM [1]. Uses: Scientific research. Group: Peptides. Alternative Names: SB-75 acetate. CAS No. 145672-81-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0009A. |  |
| Cetrorelix diacetate | Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist. Under the trade name Cetrotide, It is indicated for the inhibition of premature LH surges in women undergoing controlled ovarian stimulation. Synonyms: D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, diacetate (salt); Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2.CH3CO2H; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate salt. Grade: ≥95%. CAS No. 130143-01-0. Molecular formula: C74H100ClN17O18. Mole weight: 1551.16. | |
| DCOIT | DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor ( GnRHR )-mediated synthesis of follicle-stimulating hormone and luteinizing hormone in the brain. DCOIT interferes with G protein-coupled receptors, MAPK and Ca 2+ signaling cascades [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Kathon 930. CAS No. 64359-81-5. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-W041308. | |
| Degarelix | Degarelix acetate (FE 200486) is a decapeptide that shows high affinity/selectivity to human gonadotropin-releasing hormone (GnRH) receptor (IC 50 = 3 nM). Degarelix acetate Degarelix acetate (FE 200486) is used for the research of prostate cancer [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: FE 200486 free base. CAS No. 214766-78-6. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16168A. | |
| Degarelix | Degarelix acetate is a reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist. Degarelix reduces the secretion of luteinizing hormone (LH) and testosterone via blocking GnRHR. Degarelix can be used for the treatment of prostate cancer. Synonyms: Degarelix; Firmagon; FE-200486; FE 200486; FE200486; ASP-3550; ASP 3550; ASP3550; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Phe(4-S-dihydroorotamido)-D-Phe(4-ureido)-Leu-Lys(iPr)-Pro-D-Ala-NH2. Grade: >98%. CAS No. 214766-78-6. Molecular formula: C82H103ClN18O16. Mole weight: 1632.286. | |
| Degarelix | Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. Alternative Names: Firmagon. Uglypeptide1. SX0XJI3A11. CAS No. 214766-78-6. Product ID: API214766786. Molecular formula: C82H103ClN18O16. Mole weight: 1632.3. EINECS: 807-277-4. SMILES: CC(C)CC(C(=O)NC(CCCCNC(C)C)C(=O)N1CCCC1C(=O)NC(C)C(=O)N)NC(=O)C(CC2=CC=C(C=C2)NC(=O)N)NC(=O)C(CC3=CC=C(C=C3)NC(=O)C4CC(=O)NC(=O)N4)NC(=O)C(CO)NC(=O)C(CC5=CN=CC=C5)NC(=O)C(CC6=CC=C(C=C6)Cl)NC(=O)C(CC7=CC8=CC=CC=C8C=C7)NC(=O)C. Appearance: White to off-white amorphous powder. Category: Anti-Tumor APIs. |  |
| Degarelix acetate | Degarelix is a synthetic gonadotropin-releasing hormone receptor (GNRHR) antagonist. It decreases tumor volume of Dunning R3327H prostate tumor flank implants in rats when administered at a dose of 1 mg/kg per month. Formulations containing degarelix have been used in the treatment of advanced prostate cancer. Synonyms: Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Phe(4-S-dihydroorotamido)-D-Phe(4-ureido)-Leu-Lys(iPr)-Pro-D-Ala-NH2.CH3CO2H; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-4-((S)-dihydroorotamido)-L-phenylalanyl-4-ureido-D-phenylalanyl-L-leucyl-N6-isopropyl-L-lysyl-L-prolyl-D-alaninamide acetic acid; D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-L-phenylalanyl-4-[(aminocarbonyl)amino]-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-, acetate (1:1); FE 200486; Gonax. Grade: ≥98%. CAS No. 934016-19-0. Molecular formula: C82H103ClN18O16.C2H4O2. Mole weight: 1692.31. | |
| [Des-Ac-D-2Nal]-Cetrorelix | An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-Arg-Pro-DAla-NH2; Des-Ac-D2NalCetrorelix; D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; 4-Chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; Des-Ac-D2Nal-Cetrorelix; [Des-Ac-D-2Nal]1-Cetrorelix. Grade: ≥95%. Molecular formula: C55H79ClN16O12. Mole weight: 1191.79. | |
| [Des-D-Ala-NH2]-Cetrorelix | An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-Arg-Pro; Des-DAla-NH2-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-OH; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-proline; [Des-D-Ala-NH2]10-Cetrorelix; Des-D-Ala-Cetrorelix; 1-9 Acid Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Proline. Grade: ≥95%. CAS No. 2901757-75-1. Molecular formula: C67H86ClN15O14. Mole weight: 1360.97. | |
| Des-Ser4-Alarelin | Des-Ser4-Alarelin is a modified analog of Alarelin, a synthetic version of Gonadotropin-releasing hormone (GnRH). This modification involves the deletion of the serine residue at the 4th position, which can influence its biological activity and pharmacological properties. Synonyms: Glp-His-Trp-Tyr-DAla-Leu-Arg-Pro-NHEt; H-Pyr-His-Trp-Tyr-D-Ala-Leu-Arg-Pro-NHEt; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline ethylamide; Glp-HWY-DAla-LRP-NHEt; 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide; Glp-HWYaLRP-NHEt. Grade: ≥95%. Molecular formula: C53H73N15O10. Mole weight: 1080.26. | |
| Di-Arg-Alarelin | Di-Arg-Alarelin is a modified form of Alarelin. Alarelin is a synthetic analog of Gonadotropin-releasing hormone (GnRH) used primarily for its effects on the reproductive system. It acts as a GnRH agonist, initially stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. Alarelin is used in the treatment of conditions such as endometriosis, uterine fibroids, and prostate cancer, as well as in assisted reproductive technologies. Synonyms: Glp-His-Trp-Ser-Tyr-DAla-Leu-Arg-Arg-Pro-NHEt; H-Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Arg-Pro-NHEt; Glp-HWSY-DAla-LRRP-NHEt; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-arginyl-L-proline ethylamide; 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-arginyl-N-ethyl-L-Prolinamide; (+Arg8)-Alarelin; Glp-HWSYaLRRP-NHEt. Grade: ≥95%. Molecular formula: C62H90N20O13. Mole weight: 1323.53. | |
| Di-Ser4-Cetrorelix | An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Ser-Tyr-DCit-Leu-Arg-Pro-DAla-NH2; [Di-Ser]4-Cetrorelix; [Di-Ser4]-Cetrorelix; Di-Ser(4)-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide. Grade: ≥95%. Molecular formula: C73H97ClN18O16. Mole weight: 1518.14. | |
| D-Leu7-Cetrorelix | An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-DLeu-Arg-Pro-DAla-NH2; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-D-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-D-leucyl-L-arginyl-L-prolyl-D-alaninamide; [D-Leu]7-Cetrorelix; [D-Leu7]-Cetrorelix; D-Leu(7)-Cetrorelix. Grade: ≥95%. CAS No. 3031679-81-6. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06. | |
| D-Tyr5-Cetrorelix | An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-DTyr-DCit-Leu-Arg-Pro-DAla-NH2; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-D-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-D-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; [D-Tyr]5-Cetrorelix; [D-Tyr5]-Cetrorelix; D-Tyr(5)-Cetrorelix. Grade: ≥95%. CAS No. 3031679-86-1. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06. | |
| Elagolix | Elagolix is a Gonadotropin-Releasing Hormone (GnRH) Antagonist. Elagolix inhibits gonadatropin releasing hormone (GnRH) receptors in the pituitary gland and ultimately reduces circulating sex hormone levels. To date, elagolix has been studied in over 20 clinical trials totaling more than 1,000 subjects. A Phase 2a trial of elagolix for the treatment of uterine fibroids is also ongoing. Endometriosis can be a debilitating disease that affects millions of women around the world and the exploration of new treatments could offer other options for women with this disease. Synonyms: Elagolix, Elagolix sodium, NBI-56418; NBI 56418; NBI56418. CAS No. 834153-87-6. Molecular formula: C32H30F5N3O5. Mole weight: 631.6. | |
| Elagolix sodium | Elagolix is a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist with KD of 54 pM. It is in phase III clinical trials for the treatment of endometriosis and uterine leiomyoma. Elagolix was also under investigation for the treatment of prostate cancer and benign prostatic hyperplasia, but development for these indications was ultimately not pursued. Uses: Endometriosis; uterine leiomyoma. Synonyms: Sodium (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate; NBI56418; NBI-56418; NBI 56418. Grade: 98%. CAS No. 832720-36-2. Molecular formula: C32H29F5N3NaO5. Mole weight: 653.58. | |
| Elagolix sodium | Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (K D = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NBI-56418 sodium. CAS No. 832720-36-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14369. | |
| Elagolix Sodium | Elagolix is a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist with KD of 54 pM. It is in phase III clinical trials for the treatment of endometriosis and uterine leiomyoma. Elagolix was also under investigation for the treatment of prostate cancer and benign prostatic hyperplasia, but development for these indications was ultimately not pursued. Alternative Names: Elagolix sodium salt. Orlissa. Elagolix sodium [USAN]. CAS No. 832720-36-2. Product ID: API832720362. Molecular formula: C32H29F5N3NaO5. Mole weight: 653.6. EINECS: 692-765-8. SMILES: CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)CC(C3=CC=CC=C3)NCCCC(=O)[O-])C4=C(C(=CC=C4)OC)F.[Na+]. Category: APIs for Endometriosis. | |
| Ganirelix acetate | Ganirelix acetate (Ganirest) is an injectable competitive gonadotropin-releasing hormone (GnRH) antagonist. Ganirelix acetate directly competes against the endogenous molecule for receptor binding, and causes a rapid reduction in estradiol levels. Ganirelix acetate can be used for researching ovarian hyperstimulation syndrome (OHSS) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ganirest. CAS No. 129311-55-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-109532. | |
| Gly-Ser-Trp-Tyr-Arg | Gly-Ser-Trp-Tyr-Arg is a sequence of amino acids that can be found in the peptide gonadotropin-releasing hormone (GnRH). GnRH is a hormone that controls reproduction by stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Synonyms: mut4-FITC. | |
| GnRH II trifluoroacetate salt | GnRH II is a peptide that is encoded by the GNRH2 gene in humans. It acts as an agonist of the GnRH receptor (GnRHR). Synonyms: Gonadotropin-releasing Hormone II; ?LHRH II; 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-histidylglycyl-L-tryptophyl-L-tyrosyl-L-prolyl-glycinamide, trifluoroacetate salt. Grade: ≥95%. Molecular formula: C60H69N17O13·xCF3COOH. Mole weight: 1236.30. | |
| Goserelin acetate | Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin acetate can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: ICI-118630 acetate. CAS No. 145781-92-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13673A. | |
| Goserelin Acetate | Goserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that binds to the GNRH receptor. Synonyms: Fertilan; Zoladex; Glp-His-Trp-Ser-Tyr-[D-Ser(tBu)]-Leu-Arg-Pro-Azagly-NH2. CAS No. 145781-92-6. Molecular formula: C61H88N18O16. Mole weight: 1329.46. | |
| H-Gly-Leu-Asp-Trp-Trp-Ser-Leu-OH | Gly-Leu-Asp-Trp-Trp-Ser-Leu is part of the sequence of the decapeptide gonadotropin-releasing hormone (GnRH). GnRH is a hormone that regulates reproduction by stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Molecular formula: C43H57N9O11. Mole weight: 875.96. | |
| Nafarelin | Nafarelin is a synthetic gonadotropin-releasing hormone (GnRH) agonist that stimulates secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Synonyms: H-Pyr-His-Trp-Ser-Tyr-D-2Nal-Leu-Arg-Pro-Gly-NH2. CAS No. 76932-56-4. Molecular formula: C66H83N17O13. Mole weight: 1322.45. | |
| (+Pro5)-Alarelin | (+Pro5)-Alarelin is a modified form of Alarelin, a synthetic analog of Gonadotropin-releasing hormone (GnRH). This modification involves the introduction of a proline residue at the 5th position, which can alter its biological activity and pharmacological properties. Synonyms: Glp-His-Trp-Ser-Pro-Tyr-DAla-Leu-Arg-Pro-NHEt; H-Pyr-His-Trp-Ser-Pro-Tyr-D-Ala-Leu-Arg-Pro-NHEt; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-prolyl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline ethylamide; Glp-HWSPY-DAla-LRP-NHEt; Glp-HWYaLRP-NHEt. Grade: ≥95%. Molecular formula: C61H85N17O13. Mole weight: 1264.46. | |
| Relugolix | Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. CAS No. 737789-87-6. Product ID: API737789876. Molecular formula: C29H27F2N7O5S. | |
| Relugolix | Relugolix (TAK-385) is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. Relugolix possesses high affinity and potent antagonistic activity for human receptor (binding IC 50 =0.33 nM) and monkey receptor ( IC 50 =0.32 nM) compared with TAK-013 (HY-100209) [1]. Relugolix is used for the study of sex-hormone-dependent diseases, such as including endometriosis, uterine fibroids and prostate cancer et al [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-385. CAS No. 737789-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16474. | |
| RFRP-1(human) | RFRP-1(human) is a gonadotropin-inhibitory hormone (GnIH) homolog. RFRP-1(human) targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes and potently inhibits gonadotropin. RFRP-1(human) is a potent Neuropeptide FF (NPFF) receptor agonist with EC50s of 0.0011 nM and 29 nM for NPFF2 and NPFF1 , respectively [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 311309-25-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1428. | |
| Triptorelin Acetate | Triptorelin is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Alternative Names: pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 acetate. Decapeptyl (TN). CAS No. 140194-24-7. Product ID: API140194247. Molecular formula: C66H86N18O15. Mole weight: 1371.5. EINECS: 689-180-5. SMILES: CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CO)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CN=CN7)NC(=O)C8CCC(=O)N8.CC(=O)O. Appearance: Solid Powder. Category: Anti-Tumor APIs. | |
| Zebrafish Kisspeptin-1 | Zebrafish Kisspeptin-1 is the core sequence of the neuropeptide kisspeptin-1, which participate in the regulation of gonadotropin-releasing hormone (GnRH) release, and regulates the reproductive system [1]. Uses: Scientific research. Group: Peptides. CAS No. 1071873-79-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10419. | |
Our database is helping our users find suppliers everyday.
