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Human growthhormone is a single-chain polypeptide hormone required for the growth of tissues. Synonyms: cb311; crecormon; humatrope; ly137998; norditropin; sj0011; OVINE SOMATOTROPIN; SOMATOTROPIN. Grades: 95%. CAS No. 12629-01-5. Molecular formula: C990H1529N263O299S7. Mole weight: 22124.12.
GROWTHHORMONE RELEASING FACTOR 1-29*AMI DE, BOVINE
Compared with known standards, rec Human GrowthHormone (expressed in E. coli) is fully active in biological assays. Endotoxin level <0.1 ng per μg hGH. Synonyms: rec hGH. Grades: ≥95%.
1,2,3,4,5,6-Hexabromocyclohexane
1,2,3,4,5,6-Hexabromocyclohexane is a potent inhibitor of JAK2 tyrosine kinase autophosphorylation. It inhibits JAK2 activation, and reduces growthhormone-mediated JAK2 autophosphorylation. Synonyms: Benzene Hexabromide; JAK2 Inhibitor II. Grades: >98%. CAS No. 1837-91-8. Molecular formula: C6H6Br6. Mole weight: 557.54.
15 β-OH Gibberellin A3 Methyl Ester
15 β-OH Gibberellin A3 Methyl Ester is an intermediate in synthesizing 15 β-OH Gibberellin A3 (G377485), which is a hormone that is found in plants which promotes the growth and elongation of cells. Gibberellic Acid acts as a plant growth regulator on account of its physiological and morphological effects in extremely low concentrations. Group: Biochemicals. Grades: Highly Purified. CAS No. 105593-24-6. Pack Sizes: 500ug, 1mg. Molecular Formula: C20H24O7. US Biological Life Sciences.
Worldwide
1,6-Anhydro-b-D-galactopyranose
1,6-Anhydro-b-D-galactopyranose is a reducing sugar often used in biomedical research. As a gibberellin biosynthesis inhibitor, it is commonly utilized in the study of plant growth regulation and hormone synthesis. Additionally, it aids in the analysis of and insight into the carbohydrate structure-function relationships in bacteria and fungi. Synonyms: 6,8-Dioxa-bicylo[3,2,1]octonae-2,3,4-triol; D-Galactosan. CAS No. 644-76-8. Molecular formula: C6H10O5. Mole weight: 162.14.
17α-Hydroxyprogesterone
17α-Hydroxyprogesterone is a steroid hormone. 17α-Hydroxyprogesterone induces ovarian growth and yolk production in female crabs and increases blood pressure in sheep. 17α-Hydroxyprogesterone is mainly used in research related to crustacean reproduction and animal hypertension [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 17-Hydroxyprogesterone; 17-OHP. CAS No. 68-96-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B0891.
1- (Cyclopropylmethyl) piperazine
1- (Cyclopropylmethyl) piperazine is a compound involved in the preparation of N-substituted piperazinopyridyl steroid derivatives as abiraterone analogs that inhibit growth and induce pro-apoptosis in human hormone-independent prostate cancer cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 57184-25-5. Pack Sizes: 250mg, 1g. Molecular Formula: C8H16N2, Molecular Weight: 140.229999999999. US Biological Life Sciences.
2-((4-(tert-Butoxycarbonyl)-3-fluorophenyl)amino)-2-methylpropanoic Acid is an intermediate in the synthesis of Enzalutamide Carboxylic Acid (E559800). Enzalutamide Carboxylic Acid is used as hormone therapies to prevent androgen-fuled growth of castrate-resistant prostate cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C15H20FNO4. US Biological Life Sciences.
2 β,7-Dihydroxy-1-methyl-8-methylene-4b β-gibb-4-ene-1α,10 β-dicarboxylic Acid is a derivative of Gibberellic Acid (G377450), a hormone that is found in plants which promotes the growth and elongation of cells. Gibberellic acid acts as a plant growth regulator on account of its physiological and morphological effects in extremely low concentrations. Group: Biochemicals. Grades: Highly Purified. CAS No. 19123-84-3. Pack Sizes: 25mg, 100mg. Molecular Formula: C19H24O6. US Biological Life Sciences.
(2E)-5-(tert-Butyloxycarbonylamino)-5-methylhex-2-enoic Acid is used in the preparation of C-terminal sulfonamide analogs of NN703 as growthhormone secretagogues. Group: Biochemicals. Grades: Highly Purified. CAS No. 181646-42-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C12H21NO4. US Biological Life Sciences.
Used in the preparation of novel isoxazole carboxamides as growthhormones. Group: Biochemicals. Grades: Highly Purified. CAS No. 24248-21-3. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
3,3',5,5'-Tetraiodo-L-thyronine sodium salt
3,3',5,5'-Tetraiodo-L-thyronine sodium saltm is the sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous hormone produced by the thyroid gland. In peripheral tissues, levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine (T3). T3 enters the cell and binds to nuclear thyroid hormone receptors, the activated hormone-receptor complex in turn triggers gene expression and produces proteins required in the regulation of cellular respiration, thermogenesis, cellular growth and differentiation, and the metabolism of proteins, carbohydrates and lipids. T3 also exhibits cardiostimulatory effects. Synonyms: L-Thyroxine NaLevothyroxine sodium; Levothyroxine sodium; L-Thyroxine sodium; Euthyrox; Unithroid; Levoxyl; eltroxin; Novothyrox; Levaxin; Letter; levothroid; Sodium levothyroxine; Sodium thyroxinate; L-Thyroxine sodium salt; Sodium L-thyroxine; synthroid; Laevoxin; Thyroxevan; Oroxine; Thyroxin sodium; sodium;(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate. Grades: ≥ 98% (HPLC). CAS No. 25416-65-3. Molecular formula: C15H10I4NNaO4. Mole weight: 798.85.
3-(Boc-amino)-3-methyl-1-butanol
3-(Boc-amino)-3-methyl-1-butanol is an intermediate used in the synthesis of (2E)-5-(tert-Butyloxycarbonylamino)-5-methylhex-2-enoic Acid (B809765), which is used in the preparation of C-terminal sulfonamide analogs of NN703 as growthhormone secretagogues. Group: Biochemicals. Grades: Highly Purified. CAS No. 167216-22-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C10H21NO3, Molecular Weight: 203.28. US Biological Life Sciences.
Worldwide
3-Indoleacetic acid
3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Indole-3-acetic acid; 3-IAA. CAS No. 87-51-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-18569.
3-Indoleacetic acid sodium
3-Indoleacetic acid (Indole-3-acetic acid) sodium is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Indole-3-acetic acid sodium; 3-IAA sodium. CAS No. 6505-45-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-18569A.
3-((tert-Butoxycarbonyl)amino)-3-methylbutanoic Acid is an intermediate used in the synthesis of (2E)-5-(tert-Butyloxycarbonylamino)-5-methylhex-2-enoic Acid (B809765), which is used in the preparation of C-terminal sulfonamide analogs of NN703 as growthhormone secretagogues. Group: Biochemicals. Grades: Highly Purified. CAS No. 129765-95-3. Pack Sizes: 250mg, 1g. Molecular Formula: C10H19NO4, Molecular Weight: 217.26. US Biological Life Sciences.
Worldwide
Abarelix
Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Synonyms: Plenaxis, PPI-149; PPI 149; PPI149; R-3827; R 3827; R3827. Grades: 98%. CAS No. 183552-38-7. Molecular formula: C72H95ClN14O14. Mole weight: 1416.09.
Abscisic acid
Abscisic acid ((S)-(+)-Abscisic acid), an orally active phytohormone in fruits and vegetables, is an endogenously produced mammalian hormone. Abscisic acid is a growth inhibitor and can regulate many aspects of plant growth and development. Abscisic acid inhibits proton pump ( H + -ATPase ) and leads to the plasma membrane depolarization in a Ca 2+ -dependent manner. Abscisic acid, a LANCL2 natural ligand, is a potent insulin-sensitizing compound and has the potential for pre-diabetes, type 2 diabetes and metabolic syndrome [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (S)?-(+)?-Abscisic acid; ABA. CAS No. 21293-29-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-100560.
(+)-Abscisic acid
Abscisic acid is a plant hormone, which is involved in many plant developmental processes, modulating ion homeostasis and metabolism, and inhibiting germination and seedling growth. Uses: Plant growth regulators. Synonyms: (S)-(+)-Abscisic acid. Grades: ≥98% by HPLC. CAS No. 21293-29-8. Molecular formula: C15H20O4. Mole weight: 264.32.
Abscisic Acid Methyl Ester
Abscisic Acid Methyl Ester is an intermediate in the synthesis of Abscisic Aldehyde (A110005) which is an intermediate in the biosynthesis of the plant hormone Abscisic Acid (A110000). It is also the biosynthetic precursor of phytohormone Abscisic Acid (ABA), which regulates stress responses and controls numerous aspects of plant growth and development. Group: Biochemicals. Grades: Highly Purified. CAS No. 60102-39-8. Pack Sizes: 5mg, 10mg. Molecular Formula: C16H22O4. US Biological Life Sciences.
Worldwide
Ac-Octreotide
Ac-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growthhormone, glucagon, and insulin than somatostatin. Synonyms: Ac-D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); N-Acetyl-Phe-Octreotide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-; N-Acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2?7)-disulfide; D-Phe(Ac)-Octreotide; Ac-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7). Grades: ≥95%. CAS No. 83795-61-3. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28.
Alexamorelin Met 1
Alexamorelin Met 1 is a metabolite of Alexamorelin. The heptapeptide Ala-His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2 (Alexamorelin) is a synthetic molecule that inhibits the secretagogue binding of growthhormone in vitro. Synonyms: (D-Mrp)-Ala-Trp-(D-Phe); d-Mrp-AW-d-Phe. Grades: ≥95%. Molecular formula: C35H38N6O5. Mole weight: 622.73.
All-trans Retinol
Vitamin A is a group of unsaturated nutritional organic compounds, which includes retinol, retinal, retinoic acid, several provitamin A carotenoids, and beta-carotene. Vitamin A is important for growth and development, for the maintenance of the immune system and good vision. Vitamin A is needed by the retina of the eye in the form of retinal, which combines with protein opsin to form rhodopsin, the light-absorbing molecule necessary for both low-light (scotopic vision) and color vision. Vitamin A also functions in a very different role as retinoic acid (an irreversibly oxidized form of retinol), which is an important hormone-like growth factor for epithelial and other cells. Uses: Vitamin a is indicated only for prevention or treatment of vitamin a deficiency states. Synonyms: Vitamin A; Vitamin A1; (all-e)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol; 2,4,6,8-Nonatetraen-1-ol, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-; 21 CFR 182,5930; 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,4,6,8-nonate. Grades: >98%. CAS No. 68-26-8. Molecular formula: C20H30O. Mole weight: 286.46.
Used in the preparation of 2,4-diaminopyrimidine growthhormone secretagogue receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 885428-60-4. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Anamorelin
Anamorelin, also known as RC-1291 or ONO-7643, is the orally bioavailable, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growthhormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growthhormone-releasing effects of grhelin. Synonyms: RC 1291; RC-1291; RC1291; ONO 7643; ONO-7643; ONO7643. CAS No. 249921-19-5. Molecular formula: C31H42N6O3. Mole weight: 546.7.
Anamorelin Dihydrochloride
Anamorelin is a novel non-peptidic ghrelin mimetic and growthhormone secratogogue. Group: Biochemicals. Grades: Highly Purified. CAS No. 1469995-93-4. Pack Sizes: 10mg, 25mg. Molecular Formula: C31H44Cl2N6O3. US Biological Life Sciences.
Worldwide
Anamorelin Fumarate
Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growthhormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growthhormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite. Synonyms: RC-1291 Fumarate; ONO-7643 Fumarate; RC1291 Fumarate; ONO7643 Fumarate; RC 1291 Fumarate; ONO 7643 Fumarate. Grades: >98%. CAS No. 339539-92-3. Molecular formula: C35H46N6O7. Mole weight: 662.78.
Anamorelin HCl
Anamorelin, also known as RC-1291 or ONO-7643, is the orally bioavailable, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growthhormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growthhormone-releasing effects of grhelin. Uses: For research used only. Synonyms: RC 1291; RC1291; RC-1291; RC 1291 HCl; ONO-7643; ONO7643; ONO 7643; Anamorelin hydrochloride. Grades: 98%. CAS No. 861998-00-7. Molecular formula: C31H43ClN6O3. Mole weight: 583.174.
AOD9604
AOD 9604 is a modified fragment of human growthhormone (hGH) that is originally developed as an anti-obesity drug. AOD 9604 is formulated as the injection for weight loss, muscle building and so on. Synonyms: L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-alpha-glutamyl-glycyl-L-seryl-L-cysteinyl-glycyl-L-phenylalanine (7->14)-disulfide; AOD 9604; LAT 8881; L-Phenylalanine, L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-α-glutamylglycyl-L-seryl-L-cysteinylglycyl-, cyclic (7?14)-disulfide. CAS No. 221231-10-3. Molecular formula: C78H123N23O23S2. Mole weight: 1815.08.
AOD9604 acetate
AOD9604 acetate is a modified fragment of human growthhormone (hGH) that was originally developed as an anti-obesity drug. AOD9604 is formulated as the injection for weight loss, muscle building and so on. Synonyms: AOD-9604 acetate; AOD 9604 acetate; H-Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe-OH.CH3CO2H (Disulfide bridge: Cys7-Cys14); L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-alpha-glutamyl-glycyl-L-seryl-L-cysteinyl-glycyl-L-phenylalanine (7->14)-disulfide acetic acid; LAT 8881 acetate. Grades: ≥95%. Molecular formula: C80H127N23O25S2. Mole weight: 1875.15.
Bisindolylmaleimide I hydrochloride
Bisindolylmaleimide I hydrochloride (BMI) is a water soluble form of Bisindolylmaleimide I. It is a staurosporine inspired molecule, which has been shown to display equally potent inhibition. BIM I is a highly selective, cell-permeable, and reversible PKC inhibitor with Ki of 14 nM that is structurally similar to the poorly selective PKC inhibitor staurosporine. This compound has been used to selectively probe for PKC-mediated pathways for transduction of hormone, cytokine, and growth factor signals. It can inhibit PKC (protein kinase C) within intact platelets and T cells, Fas-mediated apoptosis, and T cell-mediated autoimmune diseases. Synonyms: BIM I; GF109203X; Gö 6850. Grades: ≥98%. CAS No. 176504-36-2. Molecular formula: C25H24N4O2·HCl. Mole weight: 449.
BMS-317180
BMS-317180 is a potent, and orally effective growthhormone secretagogue (GHS) that shows an excellent safety profile in preclinical studies. Synonyms: BMS317180; BMS 317180; (S)-2-(5-(1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl)-1H-tetrazol-1-yl)ethyl (4-hydroxybutyl)carbamate. Grades: >98%. CAS No. 295337-71-2. Molecular formula: C26H30N5O2P. Mole weight: 463.54.
Burosumab
Burosumab is a human monoclonal antibody targeting the phosphaturic hormone fibroblast growth factor 23 (FGF23). Burosumab is currently in a phase III clinical trial for the treatment of patients with X-linked hypophosphatemia. Uses: The potential treatment of x-linked hypophosphatemia. Synonyms: KRN-23; KRN 23; KRN23. CAS No. 1610833-03-8.
Buserelin-NHNH2 trifluoroacetate salt
Buserelin, sold under the brand name Suprefact among others, is a medication which is used primarily in the treatment of prostate cancer and endometriosis. Buserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that is at least 20 times more potent than GNRH. It is a long-acting agent that, after an initial increase in sex hormone levels by about 95% in both sexes, decreases the level of circulating gonadotropins and sex hormones. Buserelin can reduce tumor growth in a DMBA-induced rat model of mammary cancer. The medication is one of only two medically used GnRH analogues that are available as nasal sprays, the other being nafarelin. Buserelin is available as a generic medication. Grades: ≥95%. Molecular formula: C58H83N17O13·xCF3COOH. Mole weight: 1226.39.
Capromorelin tartrate
Capromorelin, also known as CP-424,391, is a growthhormone secretagogue and ghrelin mimetic ( hGHS-R1a K(I)=7 nM, rat pituicyte EC(50)=3 nM). Initial studies have shown the drug to directly raise insulin growth factor 1 (IGF-1) and growthhormone levels. Capromorelin showed enhanced intestinal absorption in rodent models and exhibited superior pharmacokinetic properties, including high bioavailabilities in two animal species [F(rat)=65%, F(dog)=44%]. This short-duration GHS was orally active in canine models and was selected as a development candidate for the treatment of musculoskeletal frailty in elderly adults. Group: Others. Alternative Names: CP-424,391; CP 424,391; CP424,391; CP-424391; CP 424391; CP424391; CP-424,391-18; Capromorelin tartrate. CAS No. 193273-69-7. Molecular formula: C32H41N5O10. Mole weight: 655.71. Appearance: Solid powder. Purity: >98%. IUPACName: 2-amino-N-((R)-1-((R)-3a-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)-3-(benzyloxy)-1-oxopropan-2-yl)-2-methylpropanamide (2R,3R)-2,3-dihydroxysuccinate. Canonical SMILES: CC (C) (N)C (N[C@@H] (C (N (C[C@]12CC3=CC=CC=C3)CCC1=NN (C)C2=O)=O)COCC4=CC=CC=C4)=O. O[C@H] ([C@H] (C (O)=O)O)C (O)=O. Catalog: ACM193273697.
Capromorelin Tartrate
Capromorelin Tartrate is an orally active, potent growthhormone secretagogue receptor (GHSR) agonist, with K i of 7 nM for hGHS-R1a. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 424391-18. CAS No. 193273-69-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15243.
Capromorelin Tartrate
Capromorelin Tartrate is the Tartrate salt of Capromorelin, also known as CP-424,391, which is an orally active, potent growthhormone secretagogue receptor (GHSR) agonist, with Ki of 7 nM for hGHS-R1a. Synonyms: N-[(2R)-1-[(3aR)-3a-benzyl-2-methyl-3-oxo-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]-1-oxo-3-phenylmethoxypropan-2-yl]-2-amino-2-methylpropanamide;(2R,3R)-2,3-dihydroxybutanedioic acid; Capromorelin (Tartrate); Capromorelin tartrate [USAN]; 4150VMF5EP. CAS No. 193273-69-7. Molecular formula: C32H41N5O10. Mole weight: 655.7.
CG200745
CG200745 is a novel hydroxamate-based pan-histone deacetylase inhibitor (HDACI). Like other inhibitors, CG200745 has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. CG200745 inhibited deacetylation of histone H3 and tubulin as much as vorinostat and belinostat did. CG200745 also inhibited growth of prostate cancer cells, increased sub-G1 population, and activated caspase-9, -3 and -8 in LNCaP, DU145 and PC3 cells. These results indicate that CG200745 induces apoptosis. The preclinical results show that combination treatment with docetaxel and new HDACI, CG200745, potentiated anti-tumor effect in hormone-refractory prostate cancer (HRPC) cells via activation of apoptosis. Synonyms: Ivaltinostat; CG-200745; CG-2; (E)-N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalen-1-yloxy)methyl)oct-2-enediamide. CAS No. 936221-33-9. Molecular formula: C24H33N3O4. Mole weight: 427.55.
Cimdelirsen
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense molecule designed to reduce growthhormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growthhormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients. Synonyms: ISIS 766720; ISIS-766720; ISIS766720; IONIS-GHR-LRx; all-P-ambo-5'-O-(28-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-16,16-bis{[3-({6-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]hex-yl}amino)-3-oxopropoxy]methyl}-1-hydroxy-1,10,14,21-tetraoxo-2,18-dioxa-9,15,22-triaza-1λ5-phosphaoctacosan-1-yl)-2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidylyl-(3'?5')-2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidylyl-(3'?5')-2'-O-(2-methoxyethyl)adenylyl-(3'?5')-2'-O-(2-methoxyethyl)-5-methylcytidylyl-(3'?5')-2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidylyl-(3'?5')-P-thiothymidylyl-(3'?5')-P-thiothymidylyl-(3'?5')-P-thiothymidylyl-(3'?5')-2'-deoxy-P-thioguanylyl-(3'?5')-2'-deoxy-P-thioguanylyl-(3'?5')-2'-deoxy-P-thioguanylyl-(3'?5')-P-thiothymidylyl-(3'?5')-2'-deoxy-P-thioguanylyl-(3'?5')-2'-deoxy-P-thioadenylyl-(3'?5')-2'-deoxy-P-thioadenylyl-(3'?5')-2'-O-(2-methoxyethyl)-5-methyluridylyl-(3'?5')-2'-O-(2-methoxyethyl)adenylyl-(3'?5')-2'-O-(2-methoxyethyl)-P-thioguanylyl-(3'?5')-2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidylyl-(3'?5')-2'-O-(2-methoxyethyl)adenosine. CAS No. 2131025-82-4.
(+)-cis,trans-Abscisic acid
The natural isomer of the abscission-accelerating plant hormone. (+)-Abscisic acid is a plant hormone and growth regulator involved in several physiological mechanisms including seed dormancy, leaf abscission, stomatal movement, and plant stress responses such as drought. Abscisic acid has been used in a study to learn about expression analysis of four peroxiredoxin genes from Tamarix hispida. Group: Biochemicals. Alternative Names: S-ABA, (2-cis, 4-trans,1S)-5-(1-Hydroxy-2,6,6-trimethyl) -4-oxo-2-cyclohexen-1-yl-3-methyl-2,4-pentadienoic Acid, Dormin; (S-(Z,E)])-5-(1-Hydroxy-2,6,6-trimethyl)-4-oxo-2-cyclohexen-1-yl-3- methyl-2,4-pentadienoic acid; (+)-(S)-Abscisic acid; (+)-(cis,trans)-Abscisic acid. Grades: Reagent Grade. CAS No. 21293-29-8. Pack Sizes: 250mg, 1g, 5g. Molecular Formula: C15H20O4. US Biological Life Sciences.
Worldwide
CJC1295 With DAC
CJC1295 is a synthetic analogue of growthhormone-releasing hormone. Grades: 98%. CAS No. 446262-90-4. Molecular formula: C165H269N47O46. Mole weight: 3647.19.
CJC1295 Without DAC
CJC-1295 is a 30-amino acid peptide and a growthhormone releasing hormone (GHRH) analog. It prolongs stimulation of growthhormone (GH) and insulin-like growth factor I secretion. It also extends the half-life and bioavailability of growth-hormone-releasing hormone 1-29. Synonyms: CJC 1295; CJC1295; L-tyrosyl-D-alanyl-L-alpha-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-glutaminyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-alanyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-isoleucyl-L-leucyl-L-seryl-L-argininamide. Grades: >98%. CAS No. 863288-34-0. Molecular formula: C152H252N44O42. Mole weight: 3367.9.
Coronatine
Coronatine is a plant growth regulator that mimicks the jasmonic acid-isoleucine conjugate (JA-Ile), targets the jasmonic acid receptor COI1, activates the jasmonic acid signaling pathway, thereby inhibiting salicylic acid (SA)-dependent defense responses. Coronatine antagonizes the stomatal closure, induces plant cell necrosis and chlorosis, interfers with plant hormone balance, thereby promoting pathogen infection [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 62251-96-1. Pack Sizes: 1 mg. Product ID: HY-N11420.
Cortistatin 14, human, rat
Cortistatin 14 is an endogenous neuropeptide similar to somatostatin-14 in structure and function. It is mainly expressed in the cortex and hippocampus. It shows potency at all somatostatin receptors, but prevents somatostatin-14 binding. It binds to the growthhormone secretagog receptor (GHS-R1a). It displays sleep-modulating and neuronal depressant properties in vivo. Synonyms: CST-14, human, rat; Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys (Disulfide bridge: Cys2-Cys13); Corticostatin-14; L-prolyl-L-cysteinyl-L-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-seryl-L-cysteinyl-L-lysine (2->13)-disulfide; N2-{[(4R, 7S, 10S, 13S, 16S, 19S, 22S, 25S, 28S, 31S, 34S, 37R)-19, 34-Bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13, 25, 28-tribenzyl-16-(1-hydroxyethyl)-7, 10-bis(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6, 9, 12, 15, 18, 21, 24, 27, 30, 33, 36-undecaoxo-37-(L-prolylamino)-1, 2-dithia-5, 8, 11, 14, 17, 20, 23, 26, 29, 32, 35-undecaazacyclooctatriacontan-4-yl]carbonyl}-L-lysine. Grades: ≥95%. CAS No. 193829-96-8. Molecular formula: C81H113N19O19S2. Mole weight: 1721.01.
Cyclic somatostatin diacetate
Cyclic somatostatin diacetate is a growthhormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. It's an experimental diabetes drug. Synonyms: Somatostatin (sheep), diacetate (salt); H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH.2CH3CO2H (Disulfide bridge: Cys3-Cys14); L-alanyl-glycyl-L-cysteinyl-L-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine (3->14)-disulfide diacetic acid; Somatostatin diacetate. Grades: ≥95%. CAS No. 73977-20-5. Molecular formula: C76H104N18O19S2.2C2H4O2. Mole weight: 1757.99.
Cyclosomatostatin
Cyclosomatostatin is a non-selective somatostatin (sst) receptor antagonist. It blocks the effects of CRF-induced suppression of gastric empyting and sst on airway β-adrenergic function. It also prevents growthhormone, insulin, glucagon release and modulation of ACh release. It acts as a sst receptor agonist in human neuroblastoma cell line SH-SY5Y. Uses: Hormone antagonists. Synonyms: Cyclo(7-aminoheptanonyl-Phe-D-Trp-Lys-Thr[Bzl]); Cyclo[7-aminoheptanoyl-L-phenylalanyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-L-threonyl]. CAS No. 84211-54-1. Molecular formula: C44H57N7O6. Mole weight: 779.98.
D-allo-Thr(6)-Octreotide
D-allo-Thr(6)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growthhormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-allo-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); D-Phe-Cys-Phe-D-Trp-Lys-D-allo-Thr-Cys-Thr-ol (Disulfide Bridge between Cys2-Cys7); Octreotide EP impurity-A; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-allo-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide. CAS No. 1546983-12-3. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
D-Cys(2)-Octreotide
D-Cys(2)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growthhormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-D-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide Impurity-6; H-D-Phe-D-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2?7)-disulfide; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide. CAS No. 108102-47-2. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
D-Cys(7)-Octreotide
D-Cys(7)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growthhormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-D-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide. CAS No. 1211530-36-7. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
Des-D-Phe(1)-Octreotide
Des-D-Phe(1)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growthhormone, glucagon, and insulin than somatostatin. Synonyms: L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys1-Cys6); Octreotide Impurity-F; H-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys1-Cys6); L-Cysteinamide, L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (1?6)-disulfide. Molecular formula: C40H57N9O9S2. Mole weight: 872.07.
Des-D-Trp(4)-Octreotide
Des-D-Trp(4)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growthhormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys6); Octreotide Impurity-G; H-D-Phe-Cys-Phe-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys6); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?6)-disulfide. Molecular formula: C38H56N8O9S2. Mole weight: 833.03.
Des-Lys(5)-Octreotide
Des-Lys(5)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growthhormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys6); Octreotide Impurity-H; H-D-Phe-Cys-Phe-D-Trp-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys6); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?6)-disulfide. Molecular formula: C43H54N8O9S2. Mole weight: 891.07.
[Des-octanoyl]-Ghrelin (human)
[Des-octanoyl]-Ghrelin (human) is the major circulating isoform of ghrelin that does not bind to the ghrelin receptor (GHS-R1a), nor induce growthhormone release. It exhibits negative inotropic effects in papillary muscle and cardioprotective activity. It also displays an inhibitory effect on cell proliferation in breast and prostate cancer cell lines. Synonyms: UNII-XEW3CUX2ZE; XEW3CUX2ZE. CAS No. 313951-59-6. Molecular formula: C141H235N47O41. Mole weight: 3244.51.
(Des-octanoyl)-Ghrelin (human) trifluoroacetate salt
Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growthhormone (GH) secretagogue receptor (GHS-R). Synonyms: glycyl-L-seryl-L-seryl-L-phenylalanyl-L-leucyl-L-seryl-L-prolyl-L-α-glutamyl-L-histidyl-L-glutaminyl-L-arginyl-L-valyl-L-glutaminyl-L-glutaminyl-L-arginyl-L-lysyl-L-α-glutamyl-L-seryl-L-lysyl-L-lysyl-L-prolyl-L-prolyl-L-alanyl-L-lysyl-L-leucyl-L-glutaminyl-L-prolyl-L-arginine trifluoroacetate salt. Grades: ≥95%. Molecular formula: C141H235N47O41·xCF3COOH. Mole weight: 3244.67.
[Des-octanoyl]-Ghrelin (rat)
[Des-octanoyl]-Ghrelin (rat) is the major circulating isoform of ghrelin that does not bind to the ghrelin receptor (GHS-R1a), nor induce growthhormone release. Synonyms: Des-acyl ghrelin (rat). CAS No. 307950-60-3. Molecular formula: C139H231N45O41. Mole weight: 3188.63.
Des-Threoninol-Octreotide
Des-Threoninol-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growthhormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystine (Disulfide Bridge between Cys2-Cys7); Octreotide impurity-11; H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-OH (Disulfide bridge: Cys2-Cys7); L-Cysteine, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-, cyclic (2?7)-disulfide; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteine cyclic (2?7)-disulfide. CAS No. 160841-00-9. Molecular formula: C45H57N9O9S2. Mole weight: 932.13.
Dimethyl 3-Methylglutaconate
Dimethyl 3-Methylglutaconate are shown to induce oxidative damage on striatum and the liver in rats. Also used in the preparation of insect growth regulators with juvenile hormone activity. Group: Biochemicals. Alternative Names: 3-Methyl-2-pentenedioic Acid Dimethyl Ester; 3-Methyl-glutaconic Acid Dimethyl Ester ; Dimethyl 3-Methylglutaconate; Dimethyl β-Methylglutaconate. Grades: Highly Purified. CAS No. 52313-87-8. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
[D-Lys3]-GHRP-6
[D-Lys3]-GHRP-6 is an antagonist at the ghrelin receptor (GHS-R1a) (IC50 = 0.9 μM), and a GHRP-6 antagonist. Synonyms: [D-Lys3]-GrowthHormone Releasing Peptide-6. CAS No. 136054-22-3. Molecular formula: C49H63N13O6. Mole weight: 930.12.
D-Phe(3)-Octreotide
D-Phe(3)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growthhormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-D-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); D-Phe-Cys-D-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide Bridge between Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-D-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide; D-phenylalanyl-L-cysteinyl-D-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7)-disulfide. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
D-Thr(6)-Octreotide
D-Thr(6)-0ctreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growthhormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide impurity-10; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-; H-D-Phe-Cys-Phe-D-Trp-Lys-D-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide. CAS No. 87759-89-5. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
elongation factor 2 kinase
Requires Ca2+ and calmodulin for activity. The enzyme can also be phosphorylated by the catalytic subunit of EC 2.7.11.11, cAMP-dependent protein kinase. Elongation factor 2 is phosphorylated in several cell types in response to various growth factors, hormones and other stimuli that raise intracellular Ca2+. Group: Enzymes. Synonyms: Ca/CaM-kinase III; calmodulin-dependent protein kinase III; CaM kinase III; eEF2 kinase; eEF2K; EF2K; STK19. Enzyme Commission Number: EC 2.7.11.20. CAS No. 116283-83-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3140; elongation factor 2 kinase; EC 2.7.11.20; 116283-83-1; Ca/CaM-kinase III; calmodulin-dependent protein kinase III; CaM kinase III; eEF2 kinase; eEF2K; EF2K; STK19. Cat No: EXWM-3140.
EM574
Shows strong gastrointestinal motor stimulating (GMS) activity. Motilin receptor agonist. Stimulates smooth muscle cell contraction. Stimulates cholinergic neurons in a non-vagal pathway. Enhances gastrointestinal contractile activity and accelerates gastric emptying. Shows orexigenic activity with affinity for the growth-hormone secretagogue receptor (GHS-R, ghrelin receptor). Group: Biochemicals. Grades: Highly Purified. CAS No. 110480-13-2. Pack Sizes: 250ug, 1mg. Molecular Formula: C39H69NO12. US Biological Life Sciences.
Worldwide
Enfumafungin
Enfumafungin is a triterpene glycoside and hemiacetal isolated from a fermentation of Hormonema sp. Enfumafungin is an antifungal agent that acts on fungal cell walls as an inhibitor of (1,3)-beta-D-glucan synthase. It is specific for yeast and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis. Synonyms: 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 14-(acetyloxy)-8-[(1R)-1,2-dimethylpropyl]-15-(β-D-glucopyranosyloxy)-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-4-hydroxy-1,6a,8,10a-tetramethyl-, (1S, 4aR, 6aS, 7R, 8R, 10aR, 10bR, 12aS, 14R, 15R)-. Grades: ≥98%. CAS No. 260979-95-1. Molecular formula: C38H60O12. Mole weight: 708.88.
Enzalutamide Carboxylic Acid
Enzalutamide Carboxylic Acid is a metabolite of Enzalutamide. Enzalutamide Carboxylic Acid is used as hormone therapies to prevent androgen-fuled growth of castrate-resistant prostate cancer. Synonyms: 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-benzoic Acid. CAS No. 1242137-15-0. Molecular formula: C20H13F4N3O3S. Mole weight: 451.4.
Epibrassinolide
Epibrassinolide (24-Epibrassinolide) is a ubiquitously occurring plant growthhormone which shows great potential to alleviate heavy metals and pesticide stress in plants [1]. Epibrassinolide is a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 24-Epibrassinolide; B1105; BP55. CAS No. 78821-43-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0848.
Ethynyl estradiol 17-acetate-3-(2,3,4-tri-O-acetyl-b-D-glucuronide) methyl ester, a prominent biomedical compound, exhibits remarkable efficacy in combatting hormone-responsive cancers. Its multifaceted mechanism inhibits tumor growth and curtails metastasis, thereby proving invaluable in the therapeutic management of breast, ovarian, and endometrial cancers. CAS No. 242130-33-2. Molecular formula: C35H42O12. Mole weight: 654.70.
EX1314
BMS-604992 is a selective and orally active growthhormone secretagogue receptor (GHSR) agonist with high-affinity binding (Ki = 2.3 nM) and strong functional activity (EC50 = 0.4 nM). It stimulates feeding in rodents. Synonyms: BMS-604992; Carbamic acid, (2-amino-2-oxoethyl)methyl-, (3-((1S)-1-((2-amino-2-methyl-1-oxopropyl)amino)-2-(phenylmethoxy)ethyl)-1,2,4-triazolo(4,3-a)pyridin-5-yl)methyl ester, monohydrochloride; (3-{(1S)-2-(Benzyloxy)-1-[(2-methylalanyl)amino]ethyl}[1, 2, 4]triazolo[4, 3-a]pyridin-5-yl)methyl (2-amino-2-oxoethyl)methylcarbamate hydrochloride (1:1). Grades: 98%. CAS No. 674343-47-6. Molecular formula: C24H32ClN7O5. Mole weight: 534.01.
Fmoc-Dab(Boc)-OH
Fmoc-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize somatostatin analogs that inhibit neointima formation induced by balloon injury in rats without altering growthhormone release [1]. Uses: Scientific research. Group: Peptides. CAS No. 125238-99-5. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W008024.
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