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| Product | Description | |
|---|---|---|
| 2`,3`-Dideoxy-5`-guanylic Acid | 2`,3`-Dideoxy-5`-guanylic Acid is a component used in pyrophosphorolysis activated polymerization applied to allele-specific amplification and nucleic acid sequence detection. Group: Biochemicals. Grades: Highly Purified. CAS No. 85956-71-4. Pack Sizes: 25mg, 100mg. Molecular Formula: C10H14N5O6P, Molecular Weight: 331.22. US Biological Life Sciences. |  Worldwide |
| 2'-Deoxy-5'-guanylic Acid Disodium Salt Hydrate | 2'-Deoxy-5'-guanylic Acid Disodium Salt Hydrate is a substrate of guanylate kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 146877-98-7. Pack Sizes: 500mg, 1g. Molecular Formula: C10H14N5Na2O7P. (H2O)x, Molecular Weight: 393.201801999999. US Biological Life Sciences. | Worldwide |
| 2'-O,4'-C-Methylene-5'-guanylic acid | 2'-O,4'-C-Methylene-5'-guanylic acid is an indispensable compound within the biomedical sector, finding its purpose as a catalyst for the research and development and progression of antiviral medications. Synonyms: 2-amino-9-{2,5-anhydro-4-[(phosphonooxy)methyl]-alpha-L-lyxofuranosyl}-1,9-dihydro-6H-purin-6-one. CAS No. 1152762-58-7. Molecular formula: C11H14N5O8P. Mole weight: 375.23. |  |
| 3'-O-Methyl-5'-guanylic acid | 3-O-Methyl-5-guanylic acid is a pivotal molecule extensively employed in the realm of compound is assuming an eminent position in the research and development of sundry pharmaceutical agents and investigations concerning RNA and DNA architectures. Synonyms: 3'-OMe-GMP; 3'-O-Methylguanosine-5'-Monophosphate; 3'-O-Methylguanosine 5'-phosphate; 3'-O-Methylguanosine 5'-(dihydrogen phosphate); ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)methyl dihydrogen phosphate. Grade: ≥98%. CAS No. 400806-41-9. Molecular formula: C11H16N5O8P. Mole weight: 377.25. | |
| 5'-Guanylic acid | 5'-Guanylic acid. Group: Biochemicals. CAS No. 85-32-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 5'-Guanylic acid | 5'-Guanylic acid is a purine nucleotide that participates in physiological processes such as energy metabolism, signal transduction, and gene expression regulation. 5'-Guanylic acid regulates the expression of genes related to fatty acid metabolism. 5'-Guanylic acid is the weak agonist for ionotropic glutamate receptors (iGluR), reduces the activity of the glutamatergic system and exhibits neuroprotective effect. 5'-Guanylic acid also causes neuronal cell death at high concentrations[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: 5'-GMP; 5'-guanosine monophosphate. CAS No. 85-32-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N5134. |  |
| 2'2'-cGAMP | c[A(2',5')pG(2',5')p] is a cyclic dinucleotide analogue of c[G(2',5')pA(3',5')p], the metazoan second messenger and STING activator. It can bind the signalling protein STING and induces type I interferons. Synonyms: cGAMP(2'-5'); 2'-Guanylic acid, adenylyl-(2'→5')-, cyclic nucleotide; c[G(2',5')pA(2',5')p]; 2',5'-cyclic GMP-AMP; Cyclic (adenosine-(2'→5')-monophosphate-guanosine-(2'→5')-monophosphate). Grade: ≥98% by HPLC. CAS No. 1465774-27-9. Molecular formula: C20H24N10O13P2. Mole weight: 674.41. | |
| 2',3'-cGAMP | 2',3'-cGAMP was considered to be the metazoan second messenger which is produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. It can activate innate immunity by directly binding the endoplasmic reticulum-resident receptor STING (stimulator of interferon genes). Synonyms: Cyclic [G(2',5')pA(3',5')p]; 2'-Guanylic acid, adenylyl-(3'→5')-, cyclic nucleotide; 2',3'-Cyclic guanosine adenosine monophosphate; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate; 2'-3'-cyclic GMP-AMP; cGAMP(2'→5'); c[G(2',5')pA(3',5')p]; Cyclic Gp(2'→5')Ap(3'→5'). Grade: ≥95%. CAS No. 1441190-66-4. Molecular formula: C20H24N10O13P2. Mole weight: 674.41. | |
| 2-Cyanoethyl 2-propen-1-yl 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(dimethylamino)methylene]-3'-guanylate | 2-Cyanoethyl 2-propen-1-yl 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(dimethylamino)methylene]-3'-guanylate is a noteworthy compound with diverse application in biomedical research. Notably, this synthetic nucleotide analog has demonstrated efficacy in treating viral infections, including HIV and hepatitis. Researchers have also utilized this compound in oligonucleotide synthesis for genetic engineering applications. Interestingly, this multifaceted compound shows great promise as a key player in gene therapy research. Synonyms: Allyl ((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(2-(((dimethylamino)methylene)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl) (2-cyanoethyl) phosphate; 3'-Guanylic acid, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(dimethylamino)methylene]-, 2-cyanoethyl 2-propen-1-yl ester; 3'-Guanylic acid, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(dimethylamino)methylene]-, 2-cyanoethyl 2-propenyl ester. Grade: 98%. CAS No. 827602-96-0. Molecular formula: C25H40N7O8PSi. Mole weight: 625.69. | |
| 2'-Deoxy-2'-fluoroguanosine-5'-monophosphate | 2'-Deoxy-2'-fluoroguanosine-5'-monophosphate is a vital compound used in the biomedical industry. It exhibits therapeutic potential in the treatment of certain viral infections and cancer. This product could be employed as an antiviral agent, targeting viral replication pathways, or as an anticancer agent for inhibiting tumor growth. Synonyms: 2'-Deoxy-2'-fluoro-5'-guanylic acid; 2'-Fluoro-2'-deoxyguanosine-5'-monophosphate; 9-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)guanine-5'-monophosphate; 2'-deoxy-2'-fluoroguanosine 5'-(dihydrogen phosphate). Grade: ≥95% by HPLC. CAS No. 170784-58-4. Molecular formula: C10H13FN5O7P. Mole weight: 365.21. | |
| 2'-Deoxy-6-thioguanosine-5'-monophosphate | 2'-Deoxy-6-thioguanosine-5'-monophosphate is an innovative pharmaceutical entity, exquisitely designed for unveiling remarkable antiviral potency, assiduously directing its action towards impeding the pernicious propagation of RNA viruses. Deploying its inhibitory prowess upon viral enzyme activity, it efficaciously curtails the abhorrent virus's proclivity to proliferate, ensuing in a substantial amelioration of both the intensity and duration of the affliction. Synonyms: 2'-Deoxy-6-thio-5'-guanylic acid. CAS No. 15303-00-1. Molecular formula: C10H14N5O6PS. Mole weight: 363.29. | |
| 2'-Deoxyguanosine 3'-monophosphate sodium salt | 2'-Deoxyguanosine 3'-monophosphate sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Deoxyguanosine-3-Monophosphate; 2-DEOXYGUANOSINE 3-MONOPHOSPHATE SODIUM; 2-Deoxy-3-guanylic acid disodium salt. CAS No. 102814-03-9. Molecular formula: C10H12N5O7P·2Na. Mole weight: 391.19. Purity: 0.96. IUPACName: disodium;[(2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-yl]phosphate. Canonical SMILES: C1C(C(OC1N2C=NC3=C2NC(=NC3=O)N)CO)OP(=O)([O-])[O-].[Na+].[Na+]. Product ID: ACM102814039. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2'-Deoxyguanosine-5'-monophosphate | 2'-Deoxyguanosine-5'-monophosphate, a nucleotide molecule and a key player in DNA synthesis, holds immense potential in the development of antiviral drugs as well as in treating various cancers. This biochemical marker is additionally crucial in detecting and measuring DNA damage, a necessary step in studying the complex mechanisms of DNA replication and repair. Synonyms: 2'-Deoxyguanylic acid; dGMP; Deoxyguanylic acid; Deoxy-GMP; 2'-Deoxyguanosine 5'-phosphate; Deoxyguanosine 5'-monophosphate; 2'-Deoxy-GMP; 2'-Deoxy-5'-guanylic acid; Guanosine, 2'-deoxy-, 5'-(dihydrogen phosphate); 2'-Desoxyguanosine 5'-(dihydrogen phosphate); 9-(2-Deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)-2-imino-3,9-dihydro-2H-purin-6-ol. Grade: ≥98% by HPLC. CAS No. 902-04-5. Molecular formula: C10H14N5O7P. Mole weight: 347.22. | |
| 2'-O-Methylguanosine 5'-monophosphate | 2'-O-Methylguanosine 5'-monophosphate triethylammonium salt is a critical compound extensively used in the biomedical industry. It plays a crucial role in the treatment and research of various diseases, including viral infections, cancer, and neurological disorders. This product contributes to the development of targeted therapies and is an essential component in nucleic acid-based drug formulations. Its high purity and quality make it a valuable tool for biomedical research and drug discovery. Synonyms: 2'-O-Methyl-5'-guanylic acid; 2'-O-Mgmp; 2'-O-Methyl-guanosine 5'-monophosphate; 2'-O-Me-GMP; 2'-O-Methylguanosine 5'-(dihydrogen phosphate). Grade: ≥95% by HPLC. CAS No. 24121-01-5. Molecular formula: C11H16N5O8P. Mole weight: 377.25. | |
| 3',3'-cGAMP | c-(ApGp) is an analogue of c-diAMP and c-diGMP, the bacterial second messengers, which plays a role in Vibrio choleraepathogenesis and activates the production of interferon via STING. Synonyms: 3'-Guanylic acid, adenylyl-(3'→5')-, cyclic nucleotide; 2',3'-CGAMP; 3',3'-Cyclic guanosine adenosine monophosphate; cGAMP; Cyclic [G(3',5')pA(3',5')p]; Cyclic AMP-GMP; Cyclic GMP-AMP; Cyclic (adenosine monophosphate-guanosine monophosphate); c-GpAp; 3',3'-cGAMP. Grade: ≥98%. CAS No. 849214-04-6. Molecular formula: C20H24N10O13P2. Mole weight: 674.41. | |
| 5'-Phosphoryl-(3'-amino-3'-deoxyguanylyl)-(3'-5')-3'-amino-3'-deoxycytidine | 5'-Phosphoryl-(3'-amino-3'-deoxyguanylyl)-(3'-5')-3'-amino-3'-deoxycytidine is a highly significant compound extensively employed in the biomedical sector, holding immense therapeutic potential for research of viral infections. Moreover, this remarkable compound exhibits auspicious outcomes in impeding the proliferation of neoplastic cells. Synonyms: [(2R,3S,4R,5R)-4-Amino-2-[[(2R,3S,4R,5R)-4-amino-5-(4-amino-2-oxo-pyri midin-1-yl)-3-phosphonooxy-oxolan-2-yl]methoxymethyl]-5-(2-amino-6-oxo-3H-purin-9-yl)oxolan-3-yl]oxyphosphonic acid; 5'-Guanylic acid,3'-amino-3'-deoxycytidylyl-(5'-3')-3'-amino-3'-deoxy; Padgdc. CAS No. 109679-54-1. Molecular formula: C19H28N10O13P2. Mole weight: 666.43. | |
| 7-Methylguanosine 5-disphosphoimidazolide disodium | 7-Methylguanosine 5-disphosphoimidazolide disodium is an impurity of Guanosine. Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Synonyms: 5'-Guanylic acid, 7-methyl-, monoanhydride with 1H-imidazol-1-ylphosphonic acid, disodium salt; Guanosine Impurity 4 Disodium Salt; 5'-Guanylic acid, 7-methyl-, monoanhydride with 1H-imidazol-1-ylphosphonic acid, sodium salt (1:2). Grade: ≥98%. CAS No. 852155-68-1. Molecular formula: C14H18N7Na2O10P2. Mole weight: 552.27. | |
| (7R,8S,9S)-Trihydroxy-10S(N2-deoxyguanosyl-3'-phosphate)-7,8,9,10-tetrahydrobenzo[a]pyrene Triethylamine | A metabolite of the environmental carcinogen benzo(a)pyrene, which is a benzopyrene-DNA adduct formed during subchronic dietary exposure to carcinogen benzo(a)pyrene (BaP). Synonyms: [7R-(7α,8β,9α,10α)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)-3'-guanylic Acid. Molecular formula: C36H43N6O10P. Mole weight: 750.73. | |
| 8-Bromoguanosine-5'-O-monophosphate(8-br-5'-gmp) | 8-Bromoguanosine-5'-O-monophosphate(8-br-5'-gmp). Uses: Designed for use in research and industrial production. Additional or Alternative Names: SureCN2775572, 5-Guanylic acid, 8-bromo-, CTK0J7067, AG-E-59693, 21870-09-7. Product Category: Heterocyclic Organic Compound. CAS No. 21870-09-7. Molecular formula: C10H13BrN5O8P. Mole weight: 442.1. Purity: 0.96. IUPACName: [(2R,3S,4R,5R)-5-(2-amino-8-bromo-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate. Product ID: ACM21870097. Alfa Chemistry ISO 9001:2015 Certified. | |
| 8-Hydroxydeoxyguanosine 5'-monophosphate sodium salt | 8-Hydroxydeoxyguanosine 5'-monophosphate sodium salt is an indispensable resource, playing a pivotal role in probing intricate oxidative DNA impairment and mending mechanisms. It finds extensive utility in uncovering the ramifications inflicted by reactive oxygen species on afflictions like cancer and neurodegenerative ailments. Synonyms: 5'-Guanylic acid, 2'-deoxy-7,8-dihydro-8-oxo-, sodium salt (1:2). CAS No. 1679384-24-7. Molecular formula: C10H14N5O8P.2Na. Mole weight: 409.2. | |
| c-Di-GMP | c-diGMP is a bacterial second messenger and a STING ligand. Synonyms: 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide; 5GP-5GP; Cyclic di-3',5'-guanylate; Cyclic diguanylate; Cyclic diguanylate monophosphate; Cyclic-di-GMP; cGpGp; Cyclic diguanylic acid; cdiGMP; 3',5'-Cyclic diguanylic acid; c-(Gpgp); Bis(3',5')-cyclic diguanylic acid. Grade: ≥95%. CAS No. 61093-23-0. Molecular formula: C20H24N10O14P2. Mole weight: 690.41. | |
| cGAMP disodium | cGAMP diammonium activates stimulator of interferon genes (STING). cGAMP (Cyclic GMP-AMPP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. Synonyms: 3',3'-cGAMP disodium salt; 3'-Guanylic acid, adenylyl-(3'→5')-, cyclic nucleotide, disodium salt; 2',3'-CGAMP disodium salt; 3',3'-Cyclic guanosine adenosine monophosphate disodium salt; Cyclic [G(3',5')pA(3',5')p] disodium salt; Cyclic AMP-GMP disodium salt; Cyclic GMP-AMP disodium salt; Cyclic (adenosine monophosphate-guanosine monophosphate) disodium salt. Grade: 98%. CAS No. 2407516-83-8. Molecular formula: C20H22N10Na2O13P2. Mole weight: 718.37. | |
| Cyclic di-GMP disodium salt | Cyclic di-GMP is a second messenger in bacteria, which is involved in diverse prokaryotic processes, including biofilm formation, motility, virulence, and cell cycling. Cyclic di-GMP induces expression of IFN-β mRNA in vitro (EC50 = 537.8 nM) but less potently than 2'3'-cGAMP, 3'2'-cGAMP, 3'3'-cGAMP, and 2'2'-cGAMP. Synonyms: Cyclic-di-GMP.Na2; 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide, disodium salt; 5GP-5GP disodium salt; Cyclic di-3',5'-guanylate disodium salt; Cyclic diguanylate disodium salt; Cyclic diguanylate monophosphate disodium salt; Cyclic-di-GMP disodium salt; cGpGp disodium salt; Cyclic diguanylic acid disodium salt; cdiGMP disodium salt; 3',5'-Cyclic diguanylic acid; disodium salt c-(Gpgp) disodium salt; Bis(3',5')-cyclic diguanylic acid disodium salt; Cyclic di-GMP sodium salt; c-di-GMP disodium salt. Grade: ≥95%. CAS No. 2222132-40-1. Molecular formula: C20H22N10Na2O14P2. Mole weight: 734.37. | |
| FULLY PROTECTED DEOXYNUCLEOTIDE DIMER D( APGP) | FULLY PROTECTED DEOXYNUCLEOTIDE DIMER D( APGP). Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 278-844-6, 3-Guanylic acid, N-benzoyl-5-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(2-chlorophenyl)-2-deoxyadenylyl-(3.5)-2-deoxy-N-(2-methyl-1-oxopropyl)-, 2-chlorophenyl 2-cyanoethyl ester, 78111-52-1. Product Category: Heterocyclic Organic Compound. CAS No. 78111-52-1. Molecular formula: C67H63Cl2N11O16P2. Mole weight: 1411.134744 [g/mol]. Purity: 0.96. IUPACName: [(2R,3S,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-3-yl] [(2R,3S,5R)-3-[(2-chlorophenoxy)-(2-cyanoethoxy)phosphoryl]oxy-5-[2-(2-methylpropanoylamino)-6-oxo-3H-purin-9-yl]oxolan-2-yl]methyl (2-chlorophenyl) phosphate. Canonical SMILES: CC(C)C(=O)NC1=NC(=O)C2=C(N1)N(C=N2)C3CC(C(O3)COP(=O)(OC4CC(OC4COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)N8C=NC9=C8N=CN=C9NC(=O)C1=CC=CC=C1)OC1=CC=CC=C1Cl)OP(=O)(OCCC#N)OC1=CC=CC=C1Cl. ECNumber: 278-844-6. Product ID: ACM78111521. Alfa Chemistry ISO 9001:2015 Certified. | |
| GMP | Guanosine 5'-monophosphate has been found to be useful in studies of modulation of glutamatergic neurotransmission. Synonyms: Guanosine-5'-monophosphate; 5'-Guanylic Acid. Grade: ≥ 95 % by HPLC. Molecular formula: C10H14N5O8P. Mole weight: 363.22. | |
| Guanosine-2'(3')-monophosphate disodium salt | Guanosine-2'(3')-monophosphate disodium salt, a remarkable biomedicine product, emerges as a potent weapon in combating a myriad of multifarious diseases. Its unrivaled prowess as a precursor to cyclic guanosine monophosphate, an integral second messenger orchestrating intricate cellular signaling pathways, renders it indispensable. Synonyms: Guanylic acid disodium salt; Guanosine 2'-3'-monophosphate disodium salt mixed Isomers; 2'-Guanylic acid, disodium salt; (2R,3R,4R,5R)-2-(2-amino-6-hydroxypurin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxola n-3-yl dihydrogen phosphate, sodium salt, sodium salt. Grade: 98%. CAS No. 70347-42-1. Molecular formula: C10H12N5O8PNa2. Mole weight: 407.18. | |
| Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) | Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers). Group: Biochemicals. Alternative Names: Guanylic acid disodium salt; Guanosine 2'-3'-monophosphate disodium salt mixed Isomers. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Guanosine 5'-monophosphate | Guanosine 5'-monophosphate is a purine ribonucleoside 5'-monophosphate having guanine as the nucleobase. It has a role as a metabolite, a biomarker, an Escherichia coli metabolite and a mouse metabolite. It is a guanosine 5'-phosphate and a purine ribonucleoside 5'-monophosphate. It is a conjugate acid of a guanosine 5'-monophosphate(2-). Guanosine 5 '-monophosphate is a guanine nucleotide containing one phosphate group, which is esterified into the sugar moiety and widely found in nature. Synonyms: 5-Guanylic Acid; 5'-GMP; GMP; Guanidine Monophosphate; Guanosine 5'-Phosphate; Guanosine 5'-Phosphoric Acid; Guanosine Monophosphate; Guanylic Acid. Grade: ≥95%. CAS No. 85-32-5. Molecular formula: C10H14N5O8P. Mole weight: 363.22. | |
| Guanosine 5'-monophosphate calcium salt | Calcium guanylate is a compound with formula Ca(C10H12O4N5PO4). It is the calcium salt of guanylic acid. As a food additive, it is used as a flavor enhancer and has the E number E629. Synonyms: Calcium 5'-guanylate; Guanylic acid calcium salt; calcium,[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate; 5'-Guanylic acid calcium salt; Calcium guanylate; Calcium 5'-O-phosphonatoguanosine. Grade: ≥ 95%. CAS No. 38966-30-2. Molecular formula: C10H12CaN5O8P. Mole weight: 401.28. | |
| Guanosine 5'-monophosphate disodium salt | Disodium guanylate, also known as sodium 5'-guanylate and disodium 5'-guanylate, is a natural sodium salt of the flavor enhancing nucleotide guanosine monophosphate (GMP). Disodium guanylate is a food additive with the E number E627. It is commonly used in conjunction with glutamic acid (monosodium glutamate, MSG). As it is a fairly expensive additive, it is not used independently of glutamic acid; if disodium guanylate is present in a list of ingredients but MSG does not appear to be, it is likely that glutamic acid is provided as part of another ingredient such as a processed soy protein complex. It is often added to foods in conjunction with disodium inosinate; the combination is known as disodium 5'-ribonucleotides. Disodium guanylate is produced from dried seaweed and is often added to instant noodles, potato chips and other snacks, savory rice, tinned vegetables, cured meats, and packaged soup. Synonyms: Disodium guanylate; Disodium GMP; Disodium 5'-gmp; GMP disodium salt; 5'-Gmp disodium salt; Disodium guanosine-5'-monophosphate; 5'-Guanylic acid disodium salt; Sodium 5'-guanylate; Guanosine 5'-phosphate disodium salt. Grade: 98%. CAS No. 5550-12-9. Molecular formula: C10H12N5Na2O8P. Mole weight: 407.18. | |
| Guanosine 5'-Monophosphate Ester 6-Deoxytalose Sodium Salt | Guanosine 5'-Monophosphate Ester 6-Deoxytalose Sodium Salt is used in the synthetic preparation of nucleoside monophosphate sugars such as GMP-Fucose. Synonyms: 5'-Guanylic Acid Mono(6-deoxy-α-L-galactopyranosyl) Ester Sodium Salt. Molecular formula: C16H23N5NaO12P. Mole weight: 531.34. | |
| Guanosine-5'-O-(2-thiodiphosphate) | GDP-βS is guanosine 5'-O-(2-thiodiphosphate), a modified form of guanosine diphosphate (GDP) where the oxygen in the β-phosphate position is replaced by a sulfur atom. It is commonly used as a non-hydrolyzable analog of GDP in biochemical studies to investigate GTPase activity, signal transduction pathways, and molecular mechanisms involving GTP-binding proteins (G proteins). Synonyms: 5'-Guanylic acid, anhydride with phosphorothioic acid (1:1); 5'-Guanylic acid, monoanhydride with phosphorothioic acid; GDP-βS; Guanosine 5'-(β-thiodiphosphate); Guanosine 5'-O-(2-thiodiphosphate); Guanosine 5'-O-(β-thiodiphosphate); Guanyl-5'-yl thiophosphate. Grade: ≥90% by HPLC. CAS No. 71376-97-1. Molecular formula: C10H15N5O10P2S. Mole weight: 459.27. | |
| Guanosine 5'-O-(2-Thiodiphosphate) Trilithium Salt | Guanosine 5'-O-(2-Thiodiphosphate) Trilithium Salt is a GDP analog which could inhibits G-protein activation. Synonyms: 5'-Guanylic acid, monoanhydride with phosphorothioic acid, trilithium salt; EINECS 308-328-9; Guanosine 5'-O-(2-thiodiphosphate) trilithium salt; trilithium; [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dioxidophosphinothioyl phosphate; Guanosine 5'-[beta-thio]diphosphate trilithium salt; GDP-beta-S-Li3; GDPbetaS trilithium salt; Guanosine 5'-O-(2-Thiodiphosphate), Trilithium Salt; MFCD00057735; Guanosine 5-O-(2-thiodiphosphate)trilithium salt; Guanosine,5'-esterwith thiodiphosphoric acid([(ho)2p(o)]2s)(9ci); Guanosine 5'-[beta-thio]diphosphate trilithium salt, >=85% (HPLC), powder. CAS No. 97952-36-8. Molecular formula: C10H12Li3N5O10P2S. Mole weight: 477.07. | |
| Guanylyl-(3'-5')-cytidine | Guanylyl-3',5'-cytidine, a biochemical compound, is a valuable tool in the biomedical industry for delving deep into the intricacies of RNA capping mechanisms. It mimics guanosine 5-triphosphate (GTP), a naturally occurring molecule, and is utilized to investigate the cellular processes of various RNA viruses, including hepatitis C virus (HCV). Furthermore, guanylyl-3',5'-cytidine holds the promise of therapeutic benefits for HCV and other RNA viral infections. Synonyms: Guanylyl-3',5'-cytidine; Guanylyl-(3',5')-cytidine; GpC RNA Dinucleotide (5'-3'); Cytidylyl-(5'->3')-guanosine; 3'-Guanylic acid, 5'-ester with cytidine; Guanosine, cytidylyl-(5'→3')-; Guanylyl-(3'→5')-cytidine; GC; GpC. Grade: 95%. CAS No. 4785-04-0. Molecular formula: C19H25N8O12P. Mole weight: 588.42. | |
| Guanylyl-(3'-5')-guanosine | Guanylyl-(3'-5')-guanosine is a highly significant compound extensively employed in biomedical research, emerging as an indispensable player in signal transduction. Its pivotal role lies in its capacity to function as a second messenger molecule, especially in the modulation of cyclic GMP levels. Diverse cellular phenomena, encompassing vasodilation, neurotransmission and immune responses is are meticulously investigated utilizing this molecule to scrutinize the cGMP-dependent pathways. Synonyms: GpG RNA Dinucleotide (5'-3'); 3'-Guanylic acid, 3',5'-ester with guanosine; Guanylyl-(3'→5')-guanosine; GmpG; GpG; Guanosyl(3',5')guanosine. Grade: ≥95% by AX-HPLC. CAS No. 3353-33-1. Molecular formula: C20H25N10O12P. Mole weight: 628.45. | |
| Guanylyl-(3'-5')-uridine | Guanylyl-(3'-5')-uridine is a dinucleotide derivative that participates in RNA capping processes. It is involved in the addition of a guanosine cap to the 5' end of RNA molecules during RNA processing, essential for mRNA stability and translation initiation. It is utilized in biochemical and molecular biology research to investigate RNA-related processes, including RNA capping mechanisms, mRNA processing, and interactions with RNA-binding proteins. This compound serves as a valuable tool in elucidating the roles of modified nucleotides in RNA biology and in studying enzymatic reactions involving RNA molecules. Synonyms: GmpU; Guanylyl(3'-5')uridine; 3'-Guanylic acid, 5'-ester with uridine; Guanosine, uridylyl-(5'→3')-; Guanylyl-(3'→5')-uridine; GU; Guanosyl-(3',5')-uridine; Guanylyl-(3',5')-uridine; NSC 92173; GU dinucleotide. Grade: ≥98%. CAS No. 4785-7-3. Molecular formula: C19H24N7O13P. Mole weight: 589.41. | |
| hypoxanthine phosphoribosyltransferase | Guanine and 6-mercaptopurine can replace hypoxanthine. Group: Enzymes. Synonyms: IMP pyrophosphorylase; transphosphoribosidase; hypoxanthine-guanine phosphoribosyltransferase; guanine phosphoribosyltransferase; GPRT; HPRT; guanosine 5'-phosphate pyrophosphorylase; IMP-GMP pyrophosphorylase; HGPRTase; 6-hydroxypurine phosphoribosyltransferase; 6-mercaptopurine phosphoribosyltransferas. Enzyme Commission Number: EC 2.4.2.8. CAS No. 9016-12-0. HGPRT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2691; hypoxanthine phosphoribosyltransferase; EC 2.4.2.8; 9016-12-0; IMP pyrophosphorylase; transphosphoribosidase; hypoxanthine-guanine phosphoribosyltransferase; guanine phosphoribosyltransferase; GPRT; HPRT; guanosine 5'-phosphate pyrophosphorylase; IMP-GMP pyrophosphorylase; HGPRTase; 6-hydroxypurine phosphoribosyltransferase; 6-mercaptopurine phosphoribosyltransferase; GMP pyrophosphorylase; guanine-hypoxanthine phosphoribosyltransferase; guanosine phosphoribosyltransferase; guanylate pyrophosphorylase; guanylic pyrophosphorylase; inosinate pyrophosphorylase; inosine 5'-phosphate pyrophosphorylase; inosinic acid pyrophosphorylase; inosinic pyrophosphorylase; 6-mercaptopurine phosphoribosyltransferase; purine-6-thiol phosphoribosyltransferase. Cat No: EXWM-2691. |  |
| Ribonuclease T2 from Aspergillus oryzae, Recombinant | Aspergillus oryzae Ribonuclease T2 is a member of the RNase T2 family of endonucleases that are present in a wide variety of microbial, plant and animal species. In contrast to Aspergillus oryzae Ribonuclease T1, which is an exclusively guanylic-acid specific endonuclease, all RNase T2-like enzymes are essentially base non-specific. However, RNase T2 endonucleases from different species can show slight base preferences. The fungal enzymes, including Aspargillus oryzae RNaseT2, show slight base preference in the following order: A>G>C, U. RNase T2 cleaves between the 3-phosphate residue of one base and the 5-OH residue of the adjacent nucleotide forming a 2, 3-cyclic phosphate intermediate followed by the generation of oligonucleotides with 3-phosphate residues. This enzyme is also used as a non-mammalian source of RNase in various applications. Group: Enzymes. Synonyms: Ribonuclease T2; RNase T2; Ribonuclease. Enzyme Commission Number: EC 3.1.27.1. Rnase. Mole weight: 36 kDa. Activity: ≥10,000 units per mg protein. Stability: Stable at 12-18 months at 2-8°C. Storage: Store at 2-8°C. Form: Lyophilized powder. Source: Pichia pastoris. Species: Aspergillus oryzae. Ribonuclease T2; RNase T2; Ribonuclease. Cat No: NATE-1930. | |
| 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic Acid Ethyl Ester | 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic Acid Ethyl Ester is used in various studies of stimulators of soluble guanylate cyclase. Group: Biochemicals. Grades: Highly Purified. CAS No. 256376-59-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C16H14FN3O2. US Biological Life Sciences. | Worldwide |
| 2-Cl-ATP | 2-Cl-ATP is an agonist of P2Y purinoceptor that inhibits soluble guanylate cyclase. Synonyms: 2- Chloroadenosine- 5'- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 49564-60-5. Molecular formula: C10H15ClN5O13P3 (free acid). Mole weight: 541.6 (free acid). | |
| 2-Cyclopropylcarbonyl-3-dimethylaminoacrylic Acid Methyl Ester | 2-Cyclopropylcarbonyl-3-dimethylaminoacrylic Acid Methyl Ester is an intermediate in the preparation of soluble guanylyl cyclase activators. Group: Biochemicals. Alternative Names: α -[ (Dimethylamino) methylene]- β-oxo-cyclopropanepropanoic Acid Methyl Ester;Methyl 2- (Cyclopropylcarbonyl) -3- (dimethylamino) acrylate; Methyl 2-(Cyclopropylcarbonyl)-3-(dimethylamino)prop-2-enoate. Grades: Highly Purified. CAS No. 340774-26-7. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| 2-MeS-ATP | 2-MeS-ATP is an agonist of P2Y purinoceptors that inhibits soluble guanylate cyclase. Uses: Purinergic agonists. Synonyms: 2- Methylthioadenosine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 43170-89-4. Molecular formula: C11H18N5O13P3S (free acid). Mole weight: 553.3 (free acid). | |
| 3-Cyano-2-oxo-propionic Acid Ethyl Ester Sodium Salt | 3-Cyano-2-oxo-propionic Acid Ethyl Ester Sodium Salt is used in the preparation of stimulators of soluble guanylate cyclase. Group: Biochemicals. Grades: Highly Purified. CAS No. 53544-13-1. Pack Sizes: 500mg, 1g. Molecular Formula: C6H6NNaO3, Molecular Weight: 163.11. US Biological Life Sciences. | Worldwide |
| 5'-Guanylylmethylenediphosphonate | 5'-Guanylylmethylenediphosphonate is a crucial compound used in the research of various diseases serving as a potent inhibitor of adenylate cyclase, which can help regulate intracellular cyclic AMP levels. Additionally, 5'-Guanylylmethylenediphosphonate is used in research studies to investigate the mechanism of enzyme inhibition and to develop potential therapeutic strategies targeting adenylate cyclase. Synonyms: guanosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid; 5'-guanylylmethylenebisphosphonate; GMP-P(CH2)P; GMP-PCP; Guanosine 5'-(β,γ-methylene)triphosphate; Guanosine 5'-[β,γ-methylene]triphosphoric acid; Guanylyl methylenediphosphonate. Grade: 95%. CAS No. 13912-93-1. Molecular formula: C11H18N5O13P3. Mole weight: 521.21. | |
| 5-Hydroxy-2-adamantanone | 5-Hydroxy-2-adamantanone is used in the hydrosilylation of hydroxyketones. Also used in the preparation of adamantane substituted guanylhydrazones as inhibitors of butyrylcholinesterase, natural enzymes affecting succinic acid regulation. Group: Biochemicals. Alternative Names: 1-Hydroxy-4-adamantanone; 1-Hydroxy-4-ketoadamantane; 4-Oxo-1-adamantanol; 5-Hydroxy-2-adamantanone; 5-Hydroxyadamantanone; Idramantone; Kemantan; Kemantane; 5-Hydroxy-tricyclo[3.3.1.13, 7]decanone; 5-Hydroxytricyclo[3. 3. 1. 13, 7]decan-2-one. Grades: Highly Purified. CAS No. 20098-14-0. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-390 | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-390, a luminescent marker, offers researchers a viable tool to evaluate cyclic nucleotide signaling pathways. It furnishes a mechanism to assay guanylyl cyclase action, as well as drug responsiveness. Moreover, its application has the potential for wider clinical utilization including drug delivery and cancer diagnosis. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 390, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C36H49N8O10P (free acid). Mole weight: 784.80 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-612Q | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-612Q, a fluorescent probe, designed to assist biomedical research in investigating guanylyl cyclase enzyme activity and cGMP-related signaling pathways, as well as studying the pathogenesis of cardiovascular diseases and cancer. The intricacies of this product are profound whilst remaining highly practical, offering a truly unique insight into its potential. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 612Q, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C16H24N7O7P - ATTO 612Q (free acid). Mole weight: 1131.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-647N | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-647N is a fluorescent probe used for imaging guanylyl cyclase and monitoring cGMP signaling pathways in biological systems. This product can also be utilized in the diagnosis and treatment of disorders related to the activation or inhibition of guanylyl cyclase and cGMP. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 647N, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 647N (free acid). Mole weight: 1086.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-740 | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-740, a fluorescent probe, is a valuable tool in biomedical research for investigating the function of guanylyl cyclases and soluble guanylate cyclases. Notably, this versatile probe can be used to study the mechanisms underlying cardiovascular diseases and neuronal disorders, thereby offering the potential for significant scientific breakthroughs and medical advancements. Its reliability and efficacy make it a highly sought-after compound for researchers across diverse fields. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 740, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 740 (free acid). Mole weight: 908.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cGMP - DY-776 | DY-776, a potent and selective agonist of soluble guanylate cyclase (sGC), stands as a key target for treatment of pulmonary hypertension and other cardiovascular diseases. Operating through its heme-containing domain, the DY-776 compound effortlessly binds, exhibiting increases in cyclic guanosine monophosphate (cGMP) concentrations in smooth muscle cells facilitating the enhanced vasodilation and an improved blood flow. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with DY 776. Grade: ≥ 95% by HPLC. Molecular formula: C60H72N9O15PS2 (free acid). Mole weight: 1254.37 (free acid). | |
| Acylated Linaclotide | Linaclotide is a 14 amino acid peptide that is a guanylate cyclase C agonist.It is suitable for the treatment of adult CC and IBS-C. Molecular formula: C61H81N15O22S6. Mole weight: 1568.76. | |
| Adenylyl-(3'-5')-guanosine | ADENYLYL-(3'-5')-GUANOSINE, a fundamental molecule in cellular signaling pathways, is an indispensable regulator of intracellular communication. It assumes a pivotal position in the control of diverse biological phenomena encompassing DNA synthesis and repair, cell growth, as well as immune responses. In the realm of biomedicine, ADENYLYL-(3'-5')-GUANOSINE finds utility in the investigation of second messenger signaling, cyclic nucleotide regulation, and the therapeutic management of afflictions including cancer, cardiovascular disorders, and neurodegenerative conditions. Synonyms: Guanosine, adenylyl-(3'→5')-; 3'-Adenylic acid, 5'-ester with guanosine; Adenylyl-(3'→5')-guanosine; A-G; Adenosine, guanylyl-(5'→3')-; NSC 91554; ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl) hydrogen phosphate; 3'-O-(5'-Guanylyl)adenosine. Grade: ≥95%. CAS No. 3352-23-6. Molecular formula: C20H25N10O11P. Mole weight: 612.45. | |
| Aspartyl Linaclotide | Aspartyl Linaclotide is a 14 amino acid peptide that is a guanylate cyclase C agonist.It is suitable for the treatment of adult CC and IBS-C. Molecular formula: C59H78N14O22S6. Mole weight: 1527.71. | |
| Ataciguat | Ataciguat, formerly referred to as HMR-1766, a novel anthranilic acid derivative, is a potent guanylate cyclase activator. Ataciguat has potential to treat diseases associated with increased vascular tone combined with enhanced ROS production. Uses: Ataciguat, formerly referred to as hmr-1766, a novel anthranilic acid derivative, belongs to a new structural class of sgc activators capable of activating the oxidized form of sgc. ataciguat has been shown to improve endothelial function and to reduce p. Synonyms: HMR-1766; HMR 1766; HMR1766; Ataciguat; 5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide; Ataciguat; HMR 1766. Grade: >98%. CAS No. 254877-67-3. Molecular formula: C21H19Cl2N3O6S3. Mole weight: 576.5. | |
| Atrial natriuretic factor (1-28) (human, porcine) | Atrial natriuretic factor (1-28) (human, porcine) is a 28 amino acid peptide corresponding to the rat protein sequence. It is an endogenous peptide synthesized in myoendocrine cells of the heart from which it is released into the circulation. It has effects on the renal and cardiovascular systems that decrease vasoconstriction, increase sodium excretion and inhibit renin secretion. It decreases plasma renin activity and cAMP levels in anesthetized rats and increases cGMP levels at 8 μg/kg. It also inhibits arginine vasopressin-induced increase in mean arterial blood pressure in spontaneously hypertensive and control rats when administered intracerebroventricularly at a dose of 150 ng. It produces diuretic, natriuretic and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure regulation. Synonyms: ANF 1-28; hANF; Atrial Natriuretic Peptide human. CAS No. 91917-63-4. Molecular formula: C127H205N45O39S3. Mole weight: 3080.46. | |
| Atrial Natriuretic Peptide (ANP) (1-28), rat | Atrial natriuretic factor (1-28) (rat) is a 28 amino acid peptide corresponding to the rat protein sequence. It is an endogenous peptide synthesized in myoendocrine cells of the heart from which it is released into the circulation. It has effects on the renal and cardiovascular systems that decrease vasoconstriction, increase sodium excretion and inhibit renin secretion. It decreases plasma renin activity and cAMP levels in anesthetized rats and increases cGMP levels at 8 μg/kg. It also inhibits the arginine vasopressin-induced increase in mean arterial blood pressure in spontaneously hypertensive and control rats when administered intracerebroventricularly at a dose of 150 ng. It produces diuretic, natriuretic and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure regulation. Uses: Vasodilator agents. Synonyms: Atrial natriuretic factor (1-28) (rat); rANP; Atrial Natriuretic Peptide rat; Cardiodilatin-126; Atrial Natriuretic Factor (1-28) (mouse, rabbit, rat); rANF (1-28); H-Ser-Leu-Arg-Arg-Ser-Ser-Cys(1)-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys(1)-Asn-Ser-Phe-Arg-Tyr-OH; L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanyl-glycyl-glycyl-L-arginyl-L-isole. Grade: ≥95%. CAS No. 88898-17-3. Molecular formula: C128H205N45O39S2. Mole weight: 3062 | |
| BLP-1654 | BLP-1654 is a semi-synthetic penicillin made from 6-aminopenicillanic acid (6-APA). It has anti-Gram-positive and negative bacteria activity, especially for Pseudomonas bacteria. Synonyms: 6-(D-alpha-(3-Guanylureido)phenylacetamido)penicillanic acid. Grade: >98%. CAS No. 28889-87-4. Molecular formula: C18H22N6O5S. Mole weight: 434.47. | |
| Cinaciguat | An experimental drug as an an activator of sGC in an NO-independent manner (Kd = 3.2 nM). Uses: Soluble guanylate cyclase (sgc) activators. Synonyms: BAY 58-2667; BAY 582667; BAY-58-2667; BAY582667 4-((4-carboxybutyl)(2-((4-phenethylbenzol) oxy)phenethyl)amino)methyl(benzoic) acid. Grade: ≥98.0%. CAS No. 329773-35-5. Molecular formula: C36H39NO5. Mole weight: 565.70. | |
| Creatine, anhydrous | Creatine, anhydrous. Group: Biochemicals. Alternative Names: N-(Aminoiminomethyl)-N-methylglycine; 2-(1-Methylguanidino)acetic Acid; Cosmocair C 100; Kre-Alkalyn; Methylguanidoacetic Acid; N-Methyl-N-guanylglycine; NSC 8752; Neotine; Phosphagen; Tego Cosmo C 100; [N-(Amidino)-N-methylamino]acetic Acid. Grades: Reagent Grade. CAS No. 57-00-1. Pack Sizes: 100g, 250g, 1Kg. Molecular Formula:?C?H?N?O?. US Biological Life Sciences. | Worldwide |
| CTPαS TEA salt | CTPαS, a molecule activator of soluble guanylate cyclase (sGC), is vying for a preeminent position in the study of nitric oxide signaling pathway. With its therapeutic potential locked and loaded, CTPαS is turning heads in the scientific community, demonstrating potential efficacy in addressing cardiovascular diseases such as hypertension and pulmonary arterial hypertension, as well as a wide range of central nervous system conditions, including neurodegenerative diseases and pain management alike. Synonyms: Cytidine, 5'→P''-ester with thiotriphosphoric acid TEA salt; Cytidine-5'-O-(1-thiotriphosphate) TEA salt; CTP-αS TEA salt; Cytidine-5'-(α-thio)-triphosphate, TEA salt (1:1 Mixture of Rp and Sp isomers). Grade: ≥95% by HPLC. Molecular formula: C9H16N3O13P3S (free acid). Mole weight: 499.21 (free acid). | |
| Dendroaspis Natriuretic Peptide | Dendroaspis Natriuretic Peptide, a 38-amino acid peptide originally isolated from the venom of the green mamba snake (Dendroaspis angusticeps), is structurally homologous to the natriuretic peptide family. It contains a 17-amino acid disulfide ring similar to ANP, BNP and CNP that mediate biological action through particulate guanylyl cyclase receptors and generation of guanosine monophosphate (cGMP). Synonyms: DNP; H-Glu-Val-Lys-Tyr-Asp-Pro-Cys-Phe-Gly-His-Lys-Ile-Asp-Arg-Ile-Asn-His-Val-Ser-Asn-Leu-Gly-Cys-Pro-Ser-Leu-Arg-Asp-Pro-Arg-Pro-Asn-Ala-Pro-Ser-Thr-Ser-Ala-OH (Disulfide bridge: Cys7-Cys23); L-alpha-Glutamyl-L-valyl-L-lysyl-L-tyrosyl-L-alpha-aspartyl-L-prolyl-L-cysteinyl-L-phenylalanylglycyl-L-histidyl-L-lysyl-L-isoleucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-L-asparaginyl-L-histidyl-L-valyl-L-seryl-L-asparaginyl-L-leucylglycyl-L-cysteinyl-L-prolyl-L-seryl-L-leucyl-L-arginyl-L-alpha-aspartyl-L-prolyl-L-arginyl-L-prolyl-L-asparaginyl-L-alanyl-L-prolyl-L-seryl-L-threonyl-L-seryl-L-alaninecyclic(7-23)-disulfide. Grade: ≥95% by HPLC. CAS No. 255721-52-9. Molecular formula: C180H282N56O56S2. Mole weight: 4190.64. | |
| Des-Tyr(14)-Linaclotide | Des-Tyr(14)-Linaclotide is an impurity of Linaclotide, which is a peptide agonist of guanylate cyclase 2C used for the treatment of abdominal pain in patients with irritable bowel syndrome (IBS) associated with constipation. Synonyms: L-cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparagyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteine (1->6),(2->10),(5->13)-tris(disulfide); H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-OH (Disulfide bridge: Cys1-Cys6, Cys2-Cys10, Cys5-Cys13); (3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-amino-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-6,29-(methanodithiomethano)pyrrolo[2,1-s][1,2,27,28]tetrathia[5,8,11,14,17,20,23,32,35,38,41]undecaazacyclotritetracontine-15-carboxylic acid; Linaclotide metabolite MM 419447; MM 419447; SP 340; L-Cysteine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-, cyclic (1→6),(2→10),(5→13)-tris(disulfide). CAS No. 1092457-78-7. Molecular formula: C50H70N14O19S6. Mole weight: 1363.55. | |
| Gdp | Gdp. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GUANOSINE 5'-DIPHOSPHATE;GDP DISODIUM SALT;GDP;5'-GUANYLATE DIPHOSPHATE;[[5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxyphosphonic acid;5'-guanylate diphosphate (GDP);Guanosine-5'-diphosphate disodium salt (GDP). Product Category: Heterocyclic Organic Compound. CAS No. 146-91-8. Molecular formula: C10H15N5O11P2. Mole weight: 443.2. Density: 2.63 g/cm³. Product ID: ACM146918. Alfa Chemistry ISO 9001:2015 Certified. | |
| Guanosine 3',5'-cyclic monophosphate | Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'-and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. 3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. It has a role as a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a guanyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic GMP(1-). Synonyms: 3:5-CGMP; D-Guanosine 3',5'-cyclic monophosphate; 3',5'-cyclic GMP; 2-Amino-6-oxo-6,9-dihydro-1H-purine 3-oxide; guanine-3-N-oxide; 2-Amino-1,7-dihydro-6H-purin-6-one 3-oxide; Cyclic guanosine monophosphate. Grade: ≥98%. CAS No. 7665-99-8. Molecular formula: C10H12N5O7P. Mole weight: 345.21. | |
| Guanosine-5'-carboxylic acid | Guanosine-5'-carboxylic acid, a pivotal component in the realm of biomedicine, holds immense importance. Its primary role revolves around the exploration and innovation of antiviral pharmaceuticals, with a specific focus on tackling herpes simplex and varicella-zoster viruses. By serving as a fundamental cornerstone for the synthesis of robust antiviral agents, this compound actively drives significant progress in the treatment landscape of viral ailments. Synonyms: 1-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-1-deoxy-b-D-ribofuranuronic acid; (2S,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furancarboxylic acid; 5'-Guanylsaeure; 1-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-β-D-1-deoxy-ribofuranuronic acid. Grade: ≥95%. CAS No. 15596-14-2. Molecular formula: C10H11N5O6. Mole weight: 297.22. | |
| Guanosine 5'-monophosphate,monoanhydride with(phosphonomethyl)phosphonic acid | Guanosine 5'-monophosphate,monoanhydride with(phosphonomethyl)phosphonic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: guanosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid;5'-guanylylmethylenebisphosphonate;GMP-P(CH2)P;GMP-PCP;Guanosine 5'-(β,γ-methylene)triphosphate;Guanosine 5'-[β,γ-methylene]triphosphoric acid;Guanylyl methylenediphosphonate. Product Category: Heterocyclic Organic Compound. CAS No. 13912-93-1. Molecular formula: C11H18N5O13P3. Product ID: ACM13912931. Alfa Chemistry ISO 9001:2015 Certified. | |
| Guanosine 5'-O-(2-Thiodiphosphate) Sodium Salt | Guanosine 5'-O-(2-Thiodiphosphate) Sodium Salt is a crucial compound acting as a potent inhibitor of G proteins, essential for cellular signal transduction. This product aids in research relating to G protein-coupled receptors (GPCRs), G protein-linked signaling pathways and their associated diseases such as cancer, neurodegenerative disorders and cardiovascular diseases. Synonyms: Gdp(Beta-S) Sodium Salt; GDP-Beta-S Sodium Salt; Guanyl-5'-yl Thiophosphate Sodium Salt; GDP-BS Sodium Salt; Guanosine 5'-(Trihydrogen 3-Thiodiphosphate) Sodium Salt. Molecular formula: C10H15N5O10P2S (free acid). Mole weight: 459.27 (free acid). | |
| Guanylurea sulfate | Guanylurea sulfate. Group: other glass and ceramic materials. Alternative Names: diaminomethylideneurea,sulfuric acid. CAS No. 591-01-5. Product ID: diaminomethylideneurea; sulfuric acid. Molecular formula: 302.27. Mole weight: C4< / sub>H12< / sub>N8< / sub>O2< / sub>. H2< / sub>SO4< / sub>. IATXFPUBPMZBPH-UHFFFAOYSA-N. 98%. |  |
| Guanylyl-3'-5'-adenosine triethylammonium salt | Guanylyl-3'-5'-adenosine triethylammonium salt is a versatile biomedical compound employed extensively within the pharmaceutical sector, emerging as a pivotal substrate for the esteemed guanylyl cyclase enzymes. This quintessential compound finds widespread utilization in an array of fundamental biochemical and pharmacological investigations, encompassing the study of cyclic GMP signaling cascade, neuropeptide release and the inducement of smooth muscle relaxation. Synonyms: GpA. Molecular formula: C20H25N10O11P·xC6H15N. Mole weight: 612.45 (free acid). | |
| N,N-Bis-boc-1-guanylpyrazole | N,N'-Bis-Boc-1-guanylpyrazole is used in the stereoselective synthesis of the bicyclic guanidine alkaloid (+)-monanchorin. Group: Biochemicals. Alternative Names: [[[ (1, 1-Dimethylethoxy) carbonyl]amino]-1H-pyrazol-1-ylmethylene]-carbamic Acid 1,1-Dimethylethyl Ester; [[[ (1, 1-Dimethylethoxy) carbonyl]amino]-1H-pyrazol-1-ylmethylene]carbamic Acid 1,1-Dimethylethyl Ester; 1-[N, N'-Di (tert-butoxycarbonyl) amidino]-1H-pyrazole; 1H-Pyrazole-1-N, N'-bis (tert-butoxycarbonyl) carboxamidine; N,N'-Bis(tert-butoxycarbonyl)-1-guanylpyrazole; N,N'-Bis(tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidine; N,N'-Bis(tert-butoxycarbonyl)-1H-pyrazole-1-carboximidamide; N,N'-Bis-Boc-1-guanylpyrazole; N,N'-Di(tert-butyl)oxycarbonyl-1H-pyrazole-1-carboximidamide; N,N'-Di-Boc-1H-pyrazole-1-carboxamidine; N,N'-Di-boc-1H-pyrazole-1-carboximidamide; [[ (tert-Butoxycarbonyl)imino] (pyrazol-1-yl)methyl]carbamic Acid tert-Butyl Ester; tert-Butyl [ (tert-Butoxycarbonylimino) (pyrazol-1-yl)methyl]carbamate. Grades: Highly Purified. CAS No. 152120-54-2. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
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