Hemoglobin Suppliers USA
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Product | Description | |
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Hemoglobin Quick inquiry Where to buy Suppliers range | Hemoglobin. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS008650. Format: Neat. Product Type: Other. Shipping: Room Temperature. | |
Bovine Hemoglobin Powder Quick inquiry Where to buy Suppliers range | Bovine Hemoglobin Powder. | CA, FL & NJ |
2,2-Dimethylbutanoic Acid Quick inquiry Where to buy Suppliers range | 2,2-Dimethylbutyrate (DMB) is a potential treatment for thalassemia and hemoglobinopathies. Group: Biochemicals. Grades: Highly Purified. CAS No. 595-37-9. Pack Sizes: 10g, 25g. Molecular Formula: C6H12O2, Molecular Weight: 116.16. US Biological Life Sciences. | Worldwide |
(2Z)?-2-?(4-Ethenyl-?1,?5-?dihydro-?3-?methyl-?5-?oxo-?2H-?pyrrol-?2-?ylidene)?acetamide Quick inquiry Where to buy Suppliers range | (2Z)-2-(4-Ethenyl-1,5-dihydro-3-methyl-5-oxo-2H-pyrrol-2-ylidene)acetamide is a Bilirubin (B385300) oxidation end product that results from the oxidative degradation of heme and hemoglobin. It is hypothesized to be associated with diseases such as subarachnoid hemorrhage induced cerebral vasospasm, in addition to altering potassium channel activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 1634653-34-1. Pack Sizes: 500ug, 5mg. Molecular Formula: C9H10N2O2, Molecular Weight: 178.19. US Biological Life Sciences. | Worldwide |
Biliverdine Quick inquiry Where to buy Suppliers range | Biliverdineis a precursor of Bilirubin. Biliverdine is formed in the body from hemoglobin. The bile of amphibia and of birds contains Biliverdine only. Group: Biochemicals. Alternative Names: 3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetrametyl-1,19-dioxo-21H-biline-8,12-dipropanoic Acid; Biliverdin; Biliverdin IXα; Dehydrobilirubin; NSC 62793; Oocyan; Protobiliverdin IXα; Uteroverdine; α-Biliverdin. Grades: Highly Purified. CAS No. 114-25-0. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
Cucurbitacin D Quick inquiry Where to buy Suppliers range | Source from rhizomes of Hemsleya amabilis Diels. It might be a new therapeutic option for the treatment of endometrial and ovarian cancers, also may be a potential therapeutic agent for β-hemoglobinopathies, including sickle cell anemia and β-thalassemia. And it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells. Uses: Antitumor, resistance to chemical carcinogens, protect liver. Synonyms: 17-[(3E)-1,5-Dihydroxy-1,5-dimethyl-2-oxohex-3-en-1-yl]-2,16-dihydroxy-4,4,9,14-tetramethylestr-5-ene-3,11-dione. Grades: >98%. CAS No. 3877-86-9. Molecular formula: C30H44O7. Mole weight: 516.67. | |
Eculizumab Quick inquiry Where to buy Suppliers range | Eculizumab is a recombinant human IgG2/4κ monoclonal antibody used for the treatment of paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS). Eculizumab acts as a terminal complement inhibitor that binds to the terminal complement component 5, or C5 and suppresses the complement cascade. Uses: The treatment of pnh and ahus. Synonyms: Soliris. CAS No. 219685-50-4. | |
Efaproxiral Quick inquiry Where to buy Suppliers range | Allosteric modifier of hemoglobin (HB). Binds in the central water cavity of the Hb molecule causing a conformational change such that bound oxygen is released more readily. Antineoplastic adjunct (radiosensitizer). Group: Biochemicals. Alternative Names: 2-[4-[2-[(3,5-Dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methylpropanoic Acid; RSR 13. Grades: Highly Purified. CAS No. 131179-95-8. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
Efaproxiral Quick inquiry Where to buy Suppliers range | synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance. One use for efaproxiral is to increase the efficacy of certain chemotherapy drugs which have reduced efficacy against hypoxic tumours, and can thus be made more effective by increased offloading of oxygen into the tumour tissues. However, no benefit was seen for efaproxiral in phase III clinical trials. Synonyms: RSR13; RSR-13; RSR 13; Efaproxyn; NSC722758; (24 (35di methyl anilino) carbonyl methyl phenoxyl2 methyl proprionic acid sodium salt. CAS No. 131179-95-8. Molecular formula: C20H23NO4. Mole weight: 341.4. | |
Efaproxiral Sodium Quick inquiry Where to buy Suppliers range | Efaproxiral, a synthetic allosteric modi?er of hemoglobinoxygen binding af?nity, has been shown to bind reversibly to hemoglobin, stabilizing the deoxyhemoglobin tetramer conformation to reduce its af?nity for oxygen. Synonyms: Efaproxiral sodium; 170787-99-2; RSR13 SODIUM; Sodium 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanoate; Efaproxiral (sodium); Efaproxiral sodium [USAN]; RSR-13 SODIUM; 3L83QP52XI; 170787-99-2 (sodium); Efaproxyn; Efaproxiral sodium (USAN); Sodium 2-[4-[2-[(3,5-dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methylpropanoate; Propanoic acid, 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methyl-, monosodium salt; Efaproxiral Sodium. Grades: >98%. CAS No. 170787-99-2. Molecular formula: C20H23NO4.Na. Mole weight: 363.38. | |
GBT-440 Quick inquiry Where to buy Suppliers range | GBT-440 is a substituted benzaldehyde compound that can modulate sickle hemoglobin (HbS) for treatment of disorders. Uses: Hematologic agents. Synonyms: Voxelotor, GBT-440, GBT 440, GBT440, GTx-011, GTx011, GTx 011; 2-hydroxy-6-[[2-(2-propan-2-ylpyrazol-3-yl)pyridin-3-yl]methoxy]benzaldehyde; Hemoglobin Modulators-1. Grades: >98%. CAS No. 1446321-46-5. Molecular formula: C19H19N3O3. Mole weight: 337.37. | |
Guaiac gum Quick inquiry Where to buy Suppliers range | Gum guaiac is a tree resin and crude source of 2,5-di-(4-hydroxy-3-methoxyphenyl)-3,4-dimethylfuran (α-guaiaconic acid).[3] The phenolic α-guaiaconic acid acts as a colorimetric peroxidase substrate.[1][2][4] When reacted with an organic or inorganic oxidizing agent, the α-guaiaconic acid is oxidized to a blue-colored quinone. The guaiac reaction has been used to detect trace amounts of heme from hemoglobin in the presence of peroxide. The Nobles test can be performed using 67% (w/v) gum guaiac diluted in 96% ethanol to analyze the level of extracellular oxidase production [5]. Group: Biochemicals. Grades: Highly Purified. CAS No. 9000-29-7. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences. | Worldwide |
HBD-26 Quick inquiry Where to buy Suppliers range | HBD-26 is isolated from Homo sapiens with antibacterial activity. Synonyms: Hemoglobin subunit delta-26. | |
HBD-27 Quick inquiry Where to buy Suppliers range | HBD-27 is isolated from Homo sapiens with antibacterial activity. Synonyms: Hemoglobin subunit delta-27. | |
HBD-28 Quick inquiry Where to buy Suppliers range | HBD-28 is isolated from Homo sapiens with antibacterial activity. Synonyms: Hemoglobin subunit delta-28. | |
Hemopressin (human, mouse) acetate Quick inquiry Where to buy Suppliers range | Hemopressin (human, mouse) acetate, derived from the α1-chain of hemoglobin and originally isolated from rat brain homogenates, is a bioactive endogenous peptide substrate for endopeptidase 24.15, neurolysin and ACE (Ki = 27.76, 3.43 and 1.87 μM, respectively). It acts as a selective CB1 receptor inverse agonist with antinociceptive and hypotensive activity. Synonyms: H-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH.CH3CO2H; L-prolyl-L-valyl-L-asparagyl-L-phenylalanyl-L-lysyl-L-leucyl-L-leucyl-L-seryl-L-histidine acetic acid. Grades: ≥95%. Molecular formula: C52H83N13O14. Mole weight: 1114.29. | |
Hemorphin-7 Quick inquiry Where to buy Suppliers range | Hemorphin-7, a hemorphin peptide with antinociceptive and antihypertensive effects, is an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides activates opioid receptors and inhibiting angiotensin-converting enzyme (ACE). The much lower affinity of hemorphin- 7 for μ-receptors as compared to other opioid peptides may be compensated by its much higher plasma concentration, resulting in biological effects of comparable magnitude. Synonyms: H-Tyr-Pro-Trp-Thr-Gln-Arg-Phe-OH; L-tyrosyl-L-prolyl-L-tryptophyl-L-threonyl-L-glutaminyl-L-arginyl-L-phenylalanine; L-Phenylalanine, N-(N2-(N2-(N-(N-(1-L-tyrosyl-L-prolyl)-L-tryptophyl)-L-threonyl)-L-glutaminyl)-L-arginyl)-. Grades: ≥97%. CAS No. 152685-85-3. Molecular formula: C49H64N12O11. Mole weight: 997.11. | |
Hemorphin-7 Quick inquiry Where to buy Suppliers range | Hemorphin-7 is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides exhibits antinociceptive and antihypertensive activities, activating opioid receptors and inhibiting angiotensin-converting enzyme (ACE). Uses: Peptide Inhibitors. CAS No. 152685-85-3. Product ID: R1414. | |
Hydroxyurea Quick inquiry Where to buy Suppliers range | Hydroxyurea is used as an inhibitor of DNA synthesis. As an anti-neoplastic, hydroxyurea inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide. Group: Biochemicals. Alternative Names: Carbamohydroxamic acid; N-Carbamoyl hydroxylamine; N-Hydroxyurea; Biosupressin; Carbamohydroxamic Acid; Carbamoyl Oxime; Cytodrox; Droxia; HU; Hidrix; Hydrea; Hydreia; Hydroxycarbamide; Hydroxycarbamine; N- (Aminocarbonyl) hydroxylamine; Hydroxylurea; Hydura; Hydurea; Litaler; Litalir; N-Carbamoyl hydroxylamine; NCI C04831; NSC 32065; Oxyurea; SK 22591; SQ 1089. Grades: Molecular Biology Grade. CAS No. 127-07-1. Pack Sizes: 10g, 25g, 100g, 250g, 500g. Molecular Formula: CH4N2O2, Molecular Weight: 76.06. US Biological Life Sciences. | Worldwide |
Hydroxy Urea-13C,15N2 Quick inquiry Where to buy Suppliers range | Labeled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide. Group: Biochemicals. Alternative Names: N-Hydroxyurea-13C,15N2; Biosupressin-13C,15N2; Carbamohydroxamic Acid-13C,15N2; Carbamoyl Oxime-13C,15N2; Cytodrox-13C,15N2; Droxia-13C,15N2; Hydrea-13C,15N2; Hydreia-13C,15N2; Hydroxycarbamide-13C,15N2; Hydroxycarbamine-13C,15N2; N- (Aminocarbonyl) hydroxylamine-13C, 15N2; Hydroxylurea-13C,15N2; Hydura-13C,15N2; Litaler-13C,15N2; N-Carbamoylhydroxylamine-13C,15N2; NSC 32065-13C,15N2; Oxyurea-13C,15N2; SK 22591-13C,15N2; SQ 1089-13C,15N2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Iron Quick inquiry Where to buy Suppliers range | Iron. Uses: Smelting of iron from its ore occurs in a blast furnace where carbon (coke) and limestoneare heated with the ore that results in the iron in the ore being reduced and converted tomolten iron, called "pig iron." Melted pig iron still contains some carbon and silicon as wellas some other impurities as it collects in the bottom of the furnace with molten slag floatingatop the iron. Both are tapped and drained off. This process can be continuous since moreingredients can be added as the iron and slag are removed from the bottom of the furnace.This form of iron is not very useful for manufacturing products, given that it is brittle andnot very strong.One of the major advances in the technology of iron smelting was the development of theBessemer process by Henry Bessemer (1813-1898). In this process, compressed air or oxygenis forced through molten pig iron to oxidize (burn out) the carbon and other impurities. Steelis then produced in a forced oxygen furnace, where carbon is dissolved in the iron at very hightemperatures. Variations of hardness and other characteristics of steel can be achieved with theaddition of alloys and by annealing, quench hardening, and tempering the steel.Powder metallurgy (sintering) is the process whereby powdered iron or other metals arecombined together at high pressure without high heat to fit molded forms. This process is usedto produce homogenous (uniform throughout) metal parts.One of the most useful characteristics of iron is its natural magnetism, which it loses athigh temperatures. Magnetism can also be introduced into iron products by electrical induction. Magnets of all sizes and shapes are used in motors, atom smashers, CT scanners, and TV and computer screens, toname a few uses. Super magnets can be formed by addingother elements (see cobalt) tohigh-quality iron.Iron is an important element making up hemoglobinin the blood, which carriesoxygen to the cells of ourbodies. It is also very important as a trace element inthe diet, assisting with theoxidation of foods to produce energy. We need about10 to 18 milligrams of ironeach day, as a trace mineral.Iron is found in liver andmeat products, eggs, shellfish, green leafy vegetables,peas, beans, and whole graincereals. Iron deficiency maycause anemia (low red bloodcell | |
L-Threonine methyl ester hydrochloride Quick inquiry Where to buy Suppliers range | L-Threonine methyl ester is a protected form of L-Threonine. L-Threonine is an essential amino acid that is commonly used as a feed and food additive. L-Threonine is produced in mass quantities by mutant Escherichia coli strains for research and food nutrition purposes. L-Threonine can be naturally found in fish and poultry, and is incorporated in some important proteins in the human body (such as hemoglobin and insulin). Synonyms: L-Thr-OMe HCl; methyl(2S,3R)-2-amino-3-hydroxybutanoate hydrochloride; L-Threonine methyl ester hydrochloride. Grades: ≥ 98% (HPLC). CAS No. 39994-75-7. Molecular formula: C5H11NO3·HCl. Mole weight: 169.60. | |
L-Threonine tert-butyl ester hydrochloride Quick inquiry Where to buy Suppliers range | L-Threonine tert-butyl ester is a protected form of L-Threonine. L-Threonine is an essential amino acid that is commonly used as a feed and food additive. L-Threonine is produced in mass quantities by mutant Escherichia coli strains for research and food nutrition purposes. L-Threonine can be naturally found in fish and poultry, and is incorporated in some important proteins in the human body (such as hemoglobin and insulin). Synonyms: L-Thr-OtBu HCl; (2S,3R)-tert-Butyl 2-amino-3-hydroxybutanoate hydrochloride; tert-butyl 2-amino-3-hydroxybutanoate hydrochloride. Grades: ≥ 99.9% (assay). CAS No. 69320-90-7. Molecular formula: C8H17NO3·HCl. Mole weight: 211.69. | |
MK-8617 Quick inquiry Where to buy Suppliers range | MK-8617 is a potent and selective pan-inhibitor of Hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) (PHD1: IC50 = 1.0 nM; PHD2: IC50 =1.0nM; PHD3: IC50 = 14nM) commonly used for the treatment of Anemia, a disease caused by inadequate red blood cells (RBCs) or hemoglobin (Hb). Synonyms: MK-8617; MK 8617; MK8617; UNII-39RRC0G27V; 39RRC0G27V; SCHEMBL3407165; AKOS030622836; N-[bis(4-methoxyphenyl)methyl]-6-oxo-2-pyridazin-3-yl-1H-pyrimidine-5-carboxamide. Grades: 99.39 %. CAS No. 1187990-87-9. Molecular formula: C24H21N5O4. Mole weight: 443.45. | |
myo-Inositol-d6 Trispyrophosphate Hexasodium Salt Quick inquiry Where to buy Suppliers range | Labeled myo-Inositol Trispyrophosphate hexasodium. A novel membrane-permeant allosteric effector of hemoglobin (Hb), enhances the regulated oxygen release capacity of red blood cells, thus counteracting the effects of hypoxia in diseases such as cancer and cardiovascular ailments. Group: Biochemicals. Alternative Names: ITTP-d6 Hexasodium Salt; myo-Inositol-d6 Cyclic 1,2:3,4:5,6-Tris(dihydrogen pyrophosphate)) Hexasodium Salt; myo-Inositol-d6 Cyclic 1,2:3,4:5,6-Tris(P,P'-dihydrogen diphosphate) Hexasodium Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
myo-Inositol Trispyrophosphate Hexasodium Salt Quick inquiry Where to buy Suppliers range | A novel membrane-permeant allosteric effector of hemoglobin (Hb), enhances the regulated oxygen release capacity of red blood cells, thus counteracting the effects of hypoxia in diseases such as cancer and cardiovascular ailments. Group: Biochemicals. Alternative Names: ITTP Hexasodium Salt; myo-Inositol Cyclic 1,2:3,4:5,6-Tris(dihydrogen pyrophosphate)) Hexasodium Salt; myo-Inositol Cyclic 1,2:3,4:5,6-Tris(P,P'-dihydrogen diphosphate) Hexasodium Salt. Grades: Highly Purified. CAS No. 23103-35-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Rhodamine B hydrazide Quick inquiry Where to buy Suppliers range | Rhodamine B hydrazide is a water-soluble fluorescent probe used for the detection of copper, peroxynitrite, nitric oxide, hydrogen peroxide, glucose, diacetyl, and hemoglobin. Synonyms: 2-amino-3',6'-bis(diethylamino)-spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one. Grades: ≥98%. CAS No. 74317-53-6. Molecular formula: C28H32N4O2. Mole weight: 456.6. | |
RN 1 dihydrochloride Quick inquiry Where to buy Suppliers range | RN 1 is a potent lysine specific demethylase 1 (LSD1) inhibitor (IC50 = 70 nM), which exhibits selectivity for LSD1 over MAO-A and MAO-B (IC50= 0.51 and 2.79 μM for MAO-A and MAO-B, respectively). It blocks long-term but not short-term memory in mice following intraperitoneal administration. RN-1 also induces cytotoxicity in ovarian cancer cell lines and induces fetal hemoglobin synthesis while reducing disease pathology in sickle cell mice. Synonyms: RN 1 dihydrochloride; RN-1 dihydrochloride; RN1 dihydrochloride; 1- (4-methyl-1-piperazinyl) -2-[[ (1R*, 2S*) -2-[4-phenylmethoxy) phenyl]cyclopropyl]amino]ethanone dihydrochloride; RN-1, monohydrochloride; RN-1 2HCl. Grades: ≥97% by HPLC. CAS No. 1781835-13-9. Molecular formula: C23H29N3O2.2HCl. Mole weight: 452.42. | |
Valorphin Quick inquiry Where to buy Suppliers range | Valorphin is an endogenous hemoglobin β-chain (33-39) fragment. Valorphin has opioid analgesic activity, binds to rat mu-opioid receptor, with an IC50 of 14 nM. Synonyms: H-Val-Val-Tyr-Pro-Trp-Thr-Gln-OH. Grades: 95%. CAS No. 144313-54-2. Molecular formula: C44H61N9O11. Mole weight: 892.01. | |
Valorphin TFA Quick inquiry Where to buy Suppliers range | Valorphin TFA is an endogenous hemoglobin β-chain (33-39) fragment. It has opioid analgesic activity, and binds to rat mu-opioid receptor, with an IC50 of 14 nM. Synonyms: H-Val-Val-Tyr-Pro-Trp-Thr-Gln-OH.TFA; L-valyl-L-valyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-threonyl-L-glutamine trifluoroacetic acid. Grades: ≥95%. Molecular formula: C46H62F3N9O13. Mole weight: 1006.03. | |
VZHE-039 Quick inquiry Where to buy Suppliers range | VZHE-039 is a structurally-enhanced allosteric hemoglobin effector. Study in vitro showed that VZHE-039 inhibited sickling of SS erythrocytes in a dose-dependent manner. The result of in vivo studies showed that AUCtrap increased supra-proportionally with dose after I.P. administration; the limited sampling schedule suggested an I.P. bioavailability of >20%. VZHE-039 is promisingly to be a novel anti-sickling drug. Uses: Potential anti-sickling drug. Synonyms: VZHE-039; VZHE039. |