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| Product | Description | |
|---|---|---|
| HIV Protease Mutant, Recombinant | HIV-1 protease is a retroviral aspartyl protease (retropepsin) that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV protease cleaves newly synthesized polyproteins at the appropriate places to create the mature protein components of an infectious HIV virion. Without effective HIV protease, HIV virions remain uninfectious. Thus, mutation of HIV protease's active site or inhibition of its activity disrupts HIVs ability to replicate and infect additional cells, making HIV protease inhibition the subject of considerable pharmaceutical research. Group: Enzymes. Synonyms: human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease; HIV-1 retropepsin; HIV Protease Mutant; EC 3.4.23.16. Enzyme Commission Number: EC 3.4.23.16. CAS No. 144114-21-6. HIV Protease. Mole weight: mol wt ~10.8 kDa. Storage: -70°C. Form: Supplied as a solution in 0.5M Sodium Acetate, pH 4.7with 50mM Tris-HCL, 1M NaCL, 1mM EDTA, 5mM DTT and 15% glycerol. Source: E. coli. human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease; HIV-1 retropepsin; HIV Protease Mutant; EC 3.4.23.16. Pack: 100 unit vial containing > 100ug protein. Cat No: NATE-0344. |  |
| Hiv protease substrate ii | Heterocyclic Organic Compound. Alternative Names: SUC-LYS-ASP-SER-SER-LEU-TYR-PRO-ALA-LEU-THR-PHE-ASP-LYS;SUC-LYS-ASP-SER-SER-LEU-TYR-PRO-ALA-LEU-THR-PHE-ASP-LYS-OH;N-SUCCINYL-LYS-ASP-SER-SER-LEU-TYR-PRO-ALA-LEU-THR-PHE-ASP-LYS;HIV PROTEASE SUBSTRATE II;HIV SUBSTRATE II;N-succinyl-lys-asp-ser-ser-leu-ty. CAS No. 120944-74-3. Molecular formula: C72H107N15O24. Mole weight: 1566.71. Catalog: ACM120944743. |  |
| HIV Protease Substrate VI | HIV Protease Substrate VI is a sensitive chromogenic substrate for both HIV-1 and HIV-2 proteases. Synonyms: H-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2; L-arginyl-L-valyl-L-norleucyl-4-nitro-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide; L-Norleucinamide, L-arginyl-L-valyl-L-norleucyl-4-nitro-L-phenylalanyl-L-α-glutamyl-L-alanyl-. Grades: ≥95%. CAS No. 130877-92-8. Molecular formula: C40H66N12O11. Mole weight: 891.04. |  |
| Anthranilyl-HIV Protease Substrate | Anthranilyl-HIV Protease Substrate is a hexapeptide FRET substrate derived from the p24/p15 cleavage site of the gag-pol polyprotein of the virus (excitation at 280 nm, emission at >435 nm). Synonyms: Abz-TI-Nle-F(4-NO2)-QR-NH2; (2-aminobenzoyl)-L-threonyl-L-isoleucyl-L-norleucyl-4-nitro-L-phenylalanyl-L-glutaminyl-L-argininamide; H-2Abz-Thr-Ile-Nle-Phe(4-NO2)-Gln-Arg-NH2; L-Argininamide, N-(2-aminobenzoyl)-L-threonyl-L-isoleucyl-L-norleucyl-4-nitro-L-phenylalanyl-L-glutaminyl-. Grades: 95%. CAS No. 133233-38-2. Molecular formula: C43H65N13O11. Mole weight: 940.06. | |
| HIV-1 Protease, Recombinant | HIV-1 protease is a retroviral aspartyl protease (retropepsin) that is essential for the life-cycle of HIV. HIV protease cleaves newly synthesized viral polyproteins at the appropriate places into functional protein products as mature protein components of an infectious HIV virion. The mutation of HIV protease's active site or inhibition of its activity disrupts HIVs ability to replicate and infect additional cells. Group: Enzymes. Synonyms: HIV-1 retropepsin; HIV-1 Protease (PR); cd05482. Enzyme Commission Number: EC 3.4.23.-. Purity: > 90%. Mole weight: 38.4 kDa (1-99 aa + N-terminal GST and C-terminal Poly-his tags). It runs at ~31 kDa during SEC and SDS-PAGE analyses. Activity: > 1mU/mg. Stability: Stable for at least 6 months as supplied. It can be further diluted to 0.5-1 mg/ml with 50 mM Sodium acetate, 100 mM NaCl, 5 mM DTT, 5 mM EDTA, pH 5.0 containing 10% glycerol, and stored at -80°C in aliquots. Do not keep the enzyme at 4°C or -20°C for extended time. Avoid repeated freezing and thawing cycles. Storage: Store at -80°C. Form: Liquid. Source: E. coli. HIV-1 retropepsin; HIV-1 Protease (PR); cd05482; HIV1 protease. Cat No: NATE-1662. | |
| HIV-2 Protease, Recombinant | HIV-2 Protease, an aspartyl protease (retropepsin), is essential for the life-cycle of HIV-2 sub-type virus. It is expressed in the infected cells as a part of Gag-Pol polyprotein from which it is auto-catalytically released after formation of an immature viral particle. The enzyme subsequently cleaves the other parts of viral polyproteins resulting in the maturation of the virus. In HIV-infected patients, the enzyme is subjected to intensive mutagenesis and mutants resistant to applied medicines are produced as a result of the selection pressure. The mutation of HIV protease's active site or inhibition of its activity disrupts HIVs ability to replicate and infect additional ce...epsin; HIV-2 Protease (PR2); cd05482. Enzyme Commission Number: EC 3.4.23.-. Purity: > 85%. Mole weight: 38.3 kDa (1-99 aa + N-terminal GST and C-terminal Poly-his tags). It runs at ~31.5 kDa during SEC and SDS-PAGE analyses. Stability: Stable for at least 6 months as supplied. It can be further diluted to 0.5-1 mg/ml with 50 mM Sodium acetate, 100 mM NaCl, 5 mM DTT, 5 mM EDTA, pH 5.0 containing 10% glycerol, and stored at -80°C in aliquots. Do not keep the enzyme at 4°C or -20°C for extended time. Avoid repeated freezing and thawing cycles. Storage: Store at -80°C. Form: Liquid. Source: E. coli. HIV-2 retropepsin; HIV-2 Protease (PR2); cd05482; HIV2 protease. Cat No: NATE-1661. | |
| rec HIV-1 Protease (affinity purified) (expressed in E. coli) | rec HIV-1 Protease (affinity purified) (expressed in E. coli) is a crystallizable grade material suitable for co-complexing with inhibitor screens. | |
| rec HIV-1 Protease (expressed in E. coli) | rec HIV-1 Protease (expressed in E. coli), the purified material used for kinetic studies, is a protease dimer belonging to the aspartyl protease family with only 99 amino acid residues, the smallest of the retroviral proteases. The availability of this protease provides a practical way to design specific HIV-1 protease inhibitors as effective drugs for the control of AIDS. | |
| 1,2,3-Tri-O-benzoyl-4,6-O-benzylidene-b-D-galactopyranose | 1,2,3-Tri-O-benzoyl-4,6-O-benzylidene-b-D-galactopyranose is a carbohydrate derivative of high complexity and versatility. Its relevance in the pharmaceutical industry is paramount, serving as a crucial intermediate for the synthesis of a wide array of glycosides and glycoconjugates. This compound has been exploited for the development of HIV-protease inhibitors, as well as for the initiation of anti-tumor and anti-cancer drug research. Its multifaceted nature gives it immense potential for further breakthroughs in the field. Molecular formula: C34H28O9. Mole weight: 580.58. | |
| 1,3-Benzodioxole-5-sulfonyl Chloride | 1,3-Benzodioxole-5-sulfonyl Chloride is a reagent that is used in the preparation of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryloxazolidinone-5-carboxamides as novel P2 ligands. Group: Biochemicals. Grades: Highly Purified. CAS No. 115010-10-1. Pack Sizes: 1g, 10g. Molecular Formula: C7H5ClO4S, Molecular Weight: 220.63. US Biological Life Sciences. |  Worldwide |
| 1-[[[[(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione | 1-[[[[(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione is an impurity of TMC114, a bis-THF-derived compound that acts as an HIV-aspartyl protease inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 253265-98-4. Pack Sizes: 5mg, 50mg. Molecular Formula: C11H13NO7, Molecular Weight: 271.22. US Biological Life Sciences. | Worldwide |
| 1-[[[[(3S,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione | 1-[[[[(3S,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione is an impurity of TMC114, a bis-THF-derived compound that acts as an HIV-aspartyl protease inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 799241-85-3. Pack Sizes: 10mg, 100mg. Molecular Formula: C11H13NO7, Molecular Weight: 271.22. US Biological Life Sciences. | Worldwide |
| 1-[[[[(3S,3aS,6aS)-Hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione | 1-[[[[(3S,3aS,6aS)-Hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione is an impurity of TMC114, a bis-THF-derived compound that acts as an HIV-aspartyl protease inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 799241-85-3. Pack Sizes: 5mg, 50mg. Molecular Formula: C11H13NO7, Molecular Weight: 271.22. US Biological Life Sciences. | Worldwide |
| 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate | 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate is an impurity of the selective HIV protease inhibitor Ritonavir. Group: Biochemicals. Alternative Names: Thiazol-5-ylmethyl N-[(2S,3S,5S)-5-Acetamido-3-hydroxy-1,6-diphenylhexan-2-yl Carbamate; Ritonavir USP Impurity A; N-[ (1S, 2S, 4S) -4- (Acetylamino) -2-hydroxy-5-phenyl-1- (phenylmethyl) pentyl]carbamic Acid 5-Thiazolylmethyl Ester. Grades: Highly Purified. CAS No. 1010808-43-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 1-epi-Darunavir | Stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. Group: Biochemicals. Alternative Names: [ (1R, 2R) -3-[[ (4-Aminophenyl) sulfonyl] (2-methylpropyl) amino]-2-hydroxy-1- (phenyl-methyl) propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| [(1R)-1-(2R)-Oxiranyl-2-(phenylthio)ethyl]-carbamic Acid Phenylmethyl Ester | [(1R)-1-(2R)-Oxiranyl-2-(phenylthio)ethyl]-carbamic Acid Phenylmethyl Ester is used in the preparation of HIV protease inhibitor streptolysin, antibacterial Streptococcus. Group: Biochemicals. Grades: Highly Purified. CAS No. 159878-03-2. Pack Sizes: 1mg, 10mg. Molecular Formula: C18H19NO3S, Molecular Weight: 329.41. US Biological Life Sciences. | Worldwide |
| [(1R)-1-(2S)-Oxiranyl-2-(phenylthio)ethyl]-carbamic Acid Phenylmethyl Ester | [(1R)-1-(2S)-Oxiranyl-2-(phenylthio)ethyl]-carbamic Acid Phenylmethyl Ester is used in the preparation of HIV protease inhibitor streptolysin, antibacterial Streptococcus. Group: Biochemicals. Grades: Highly Purified. CAS No. 163462-16-6. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C18H19NO3S, Molecular Weight: 329.41. US Biological Life Sciences. | Worldwide |
| (1R,2S)-Darunavir | 1R,2S)-Darunavir is a diastereomer of Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. Group: Biochemicals. Grades: Highly Purified. CAS No. 1402142-63-5. Pack Sizes: 500ug, 5mg. Molecular Formula: C27H37N3O7S, Molecular Weight: 547.66. US Biological Life Sciences. | Worldwide |
| [ (1S, 2R) -1-Benzyl-2-hydroxy-3- [isobutyl- [ (4-aminophenyl) sulfonyl] amino] propyl] carbamic Acid tert-Butyl Ester | Darunavir intermediate, a potent inhibitor of HIV-1 protease. Group: Biochemicals. Alternative Names: [ (1S, 2R) -3-[[ (4-Aminophenyl) sulfonyl] (2-methylpropyl) amino]-2-hydroxy-1- (phenylmethyl) propyl]carbamic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 183004-94-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| {[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-(4-nitro-benzenesulfonyl)-amino]-propyl}-carbamic Acid, tert-butyl Ester | A intermediate in the synthesis of Amprenavir, a selective HIV protease inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| [ (1S, 2R) -1-Benzyl-2-hydroxy-3- [isobutyl-d9- [ (4-nitrophenyl) sulfonyl] amino] propyl] carbamic Acid tert-Butyl Ester | An intermediate in the synthesis of labeled Amprenavir, a selective HIV protease inhibitor. Group: Biochemicals. Alternative Names: N-[ (1S, 2R) -2-Hydroxy-3-[ (2-methylpropyl-d9) [ (4-nitrophenyl) sulfonyl]amino]-1- (phenylmethyl) propyl]carbamic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| [ (1S, 2R) -3-[[ (4-Nitrophenyl) sulfonyl] (2-methylpropyl) amino]-2-hydroxy-1-phenylmethyl) propyl]carbamic Acid, (3S)-Tetrahydro-3-furan-d4-yl Ester | A labeled intermediate in the synthesis of Amprenavir, a selective HIV protease inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| [ (1S, 2R) -3-[[ (4-Nitrophenyl) sulfonyl] (2-methylpropyl) amino]-2-hydroxy-1-phenylmethyl) propyl]carbamic Acid, (3S)-Tetrahydro-3-furanyl Ester | A intermediate in the synthesis of Amprenavir, a selective HIV protease inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 20(21)-Dehydrolucidenic Acid A | 20(21)-Dehydrolucidenic acid A is a triterpenoid isolated from the fruiting body of the fungus Ganoderma sinense. 20(21)-Dehydrolucidenic acid A has weak anti-HIV-1 protease activity. Group: Inhibitors. Alternative Names: Dehydrolucidenic acid A. CAS No. 852936-69-7. Molecular formula: C27H36O6. Mole weight: 456.57. Appearance: Solid. Purity: 0.98. IUPACName: 4-[(7S,10S,13R,14R,17R)-7-hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]pent-4-enoic acid. Canonical SMILES: C[C@]12CCC (=O)C (C1C[C@@H] (C3=C2C (=O)C[C@]4 ([C@]3 (C (=O)C[C@@H]4C (=C)CCC (=O)O)C)C)O) (C)C. Catalog: ACM852936697. | |
| 2- [ (2S, 3S) -3- [ (4R) -4- (1, 1-Dimethylethyl) -2, 5-dioxo-1-imidazolidinyl] -2-hydroxy-4-phenylbutyl] -2- [ [4- (2-pyridinyl) phenyl] methyl] hydrazide N-(Methoxycarbonyl)-3-methyl-L-valine. ((Atazanavir Cyclization product (western half) | 2- [ (2S, 3S) -3- [ (4R) -4- (1, 1-Dimethylethyl) -2, 5-dioxo-1-imidazolidinyl] -2-hydroxy-4-phenylbutyl] -2- [ [4- (2-pyridinyl) phenyl] methyl] hydrazide N-(Methoxycarbonyl)-3-methyl-L-valine, is an impurity of the drug Atazanavir (A790051), a novel azapeptide HIV protease inhibitor (PI). Antiviral. Group: Biochemicals. Grades: Highly Purified. CAS No. 1292296-13-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C37H48N6O6, Molecular Weight: 672.81. US Biological Life Sciences. | Worldwide |
| 2,3,5-Tri-O-benzyl-b-D-xylofuranose | 2,3,5-Tri-O-benzyl-b-D-xylofuranose, a critical organic synthesis intermediate, is characterized by its multifarious pharmacological activities. In addition to displaying potent antitumor properties, it also exhibits exceptional potential in diabetes treatment. Notably, it functions as an HIV-1 proteases inhibitor, positioning it as a promising therapeutic agent in the realm of viral infections. Molecular formula: C26H28O5. Mole weight: 420.50. | |
| 2,3-Dideoxy-4,5-O-(1-methylethylidene)-3-(nitromethyl)-L-threo-pentonic Acid Ethyl Ester | 2,3-Dideoxy-4,5-O-(1-methylethylidene)-3-(nitromethyl)-L-threo-pentonic Acid Ethyl Ester is an impurity in the synthesis of Darunavir (D193500). Darunavir is a second generation HIV-1-protease inhibitor, which is structurally similar to Amprenavir (A634400). Group: Biochemicals. Grades: Highly Purified. CAS No. 501921-23-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C11H19NO6, Molecular Weight: 261.27. US Biological Life Sciences. | Worldwide |
| 2,4-Phenoxy Lopinavir-d8 Impurity | 2,4-Phenoxy Lopinavir-d8 Impurity is the isotope labelled analog of 2,4-Phenoxy Lopinavir Impurity. 2,4-Phenoxy Lopinavir Impurity is a metabolite of Lopinavir (L469480); a selective HIV protease inhibitor and antiviral. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C37H40D8N4O5, Molecular Weight: 636.85. US Biological Life Sciences. | Worldwide |
| 2,4-Phenoxy Lopinavir Impurity | 2,4-Phenoxy Lopinavir Impurity is a metabolite of Lopinavir (L469480); a selective HIV protease inhibitor and antiviral. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C37H48N4O5, Molecular Weight: 628.799999999999. US Biological Life Sciences. | Worldwide |
| 2-(Acetylamino)-2-deoxy-3-O-benzoyl-4,6-O-benzylidene-D-galactopyranose Trichloroacetimidate | 2-(Acetylamino)-2-deoxy-3-O-benzoyl-4,6-O-benzylidene-D-galactopyranose Trichloroacetimidate is a valuable intermediate extensively used in the synthesis of novel drugs. It plays a crucial role in the biomedical industry by serving as a key building block for the development of antiviral agents, protease inhibitors, and drugs targeting carbohydrate-binding proteins. Additionally, this compound finds applications in research of various diseases such as HIV/AIDS, hepatitis, and cancer. Synonyms: 2-(Acetylamino)-2-deoxy-3-O-benzoyl-4,6-O-benzylidene-D-galactopyranose Trichloroacetimidate; [(4aR,7R,8R,8aR)-7-acetamido-2-phenyl-6-(2,2,2-trichloroethanimidoyl)oxy-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] benzoate; DTXSID10746907; 2-Acetamido-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-1-O-(2,2,2-trichloroethanimidoyl)-D-galactopyranose. CAS No. 390400-47-2. Molecular formula: C24H23Cl3N2O7. Mole weight: 557.81. | |
| 2-Amino-N-[1-benzyl-3-(3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydropropyl]-succinamide | Labeled Saquinavir derivative useful in immunoassay for HIV protease inhibitors. Group: Biochemicals. Alternative Names: (2S) -2-Amino-N1- [ (1S, 2R) -3- [ (3S, 4aS, 8aS) -3- [ [ (1, 1-dimethylethyl) amino] carbonyl] octahydro-2 (1H) -isoquinolinyl] -2-hydroxy-1- (phenylmethyl) propyl] -butanediamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-Benzyl-1,3-propanediol | 2-Benzyl-1,3-propanediol is used as a reagent in the asymmetric synthesis of pseudosymmetric sulfoximine inhibitors against HIV-1 protease. Also used as a reagent in the synthesis of N-(3-acyloxy-2-benzylpropyl)-N'-(4-hydroxy-3-methoxybenzyl)thiourea derivatives as potent vanilloid receptor agonists and analgesics. Group: Biochemicals. Grades: Highly Purified. CAS No. 2612-30-8. Pack Sizes: 250mg, 1g. Molecular Formula: C10H14O2, Molecular Weight: 166.22. US Biological Life Sciences. | Worldwide |
| 2-(Benzyloxy)-1-propanol | 2-(Benzyloxy)-1-propanol is used to prepare amino diol HIV-protease inhibitors. It is also used to synthesize diphenyl-substituted amino alcohols as protease inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 70448-03-2. Pack Sizes: 100mg, 1g. Molecular Formula: C10H14O2, Molecular Weight: 166.22. US Biological Life Sciences. | Worldwide |
| 2-Chloro-5-(chloromethyl)thiazole | 2-Chloro-5-(chloromethyl)thiazole is a useful synthetic intermediate used in the synthesis of Ritonavir (R535000); a second generation anti-AIDS drug and a selective HIV protease inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 105827-91-6. Pack Sizes: 5g, 10g. Molecular Formula: C4H3Cl2NS. US Biological Life Sciences. | Worldwide |
| 2-Desisopropyl-2-ethyl Ritonavir | 2-Desisopropyl-2-ethyl Ritonavir is an impurity of the selective HIV protease inhibitor Ritonavir. Group: Biochemicals. Alternative Names: (5S,8S,10S,11S)-1-(2-Ethyl-4-thiazolyl)-10-hydroxy-2-methyl-5-(1-methylethyl)-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic Acid 5-Thiazolylmethyl Ester; Ritonavir USP Impurity F; [5S-(5R*,8R*,10R*,11R*)]-1-(2-Ethyl-4-thiazolyl)-10-hydroxy-2-methyl-5-(1-methylethyl)-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic Acid 5-Thiazolylmethyl Ester. Grades: Highly Purified. CAS No. 165315-26-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (2E)-3-(2-Thiazolyl)-2-propenoic Acid | (2E)-3-(2-Thiazolyl)-2-propenoic Acid is a useful synthetic intermediate. It is used as an intermediate for HIV-1 protease inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 144163-52-0. Pack Sizes: 1g, 10g. Molecular Formula: C6H5NO2S, Molecular Weight: 155.169999999999. US Biological Life Sciences. | Worldwide |
| (2E)-3-(2-Thiazolyl)-2-propenoic Acid-13C3 | (2E)-3-(2-Thiazolyl)-2-propenoic Acid-13C3 is labelled (2E)-3-(2-Thiazolyl)-2-propenoic Acid (T344285) which is used as an intermediate for HIV-1 protease inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C313C3H5NO2S, Molecular Weight: 158.15. US Biological Life Sciences. | Worldwide |
| 2-epi-Darunavir | 2-epi-Darunavir is a stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. Group: Biochemicals. Grades: Highly Purified. CAS No. 850141-19-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C27H37N3O7S. US Biological Life Sciences. | Worldwide |
| 2-Methyl-1,3-benzoxazole-6-carboxylic Acid | 2-Methyl-1,3-benzoxazole-6-carboxylic Acid is used in the synthesis of orexin 1 receptor antagonists, used in the treatment of obesity. Also used in the synthesis of novel benzoxazole amides as novel enhancers of HIV-1 protease inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 13452-14-7. Pack Sizes: 100mg, 500 mg. Molecular Formula: C9H7NO3. US Biological Life Sciences. | Worldwide |
| 2-Methylallylamine | 2-Methylallylamine is an intermediate used in the synthesis of urea-containing FK506 binding protein inhibitors. It is also used to prepare benzothiazepine dioxides with HIV-1 protease inhibitory activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 2878-14-0. Pack Sizes: 1g, 2.5g. Molecular Formula: C4H9N, Molecular Weight: 71.12. US Biological Life Sciences. | Worldwide |
| 2-Oxopiperidine-4-carboxylic Acid | 2-Oxopiperidine-4-carboxylic Acid can be synthesized from 2-Hydroxyisonicitonic Acid (H942895), a compound used in the synthesis of selective inhibitors of neuropeptide Y Y5 inhibiting food intake. 2-Hydroxyisonicitonic Acid is also used in the optimization of p-subsite residues of HIV protease inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 24537-50-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C6H9NO3, Molecular Weight: 143.139999999999. US Biological Life Sciences. | Worldwide |
| 2-propyl isonicotinonitrile | Derivatives of 2-propyl isonicotinonitrile as HIV-1 protease inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 33744-19-3. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H10N2, Molecular Weight: 146.19. US Biological Life Sciences. | Worldwide |
| (2R, 3R) -1-Chloro-2-hydroxy-3-[ (benzyloxycarbonyl) amino]-4- (phenylthio) butane | (2R, 3R) -1-Chloro-2-hydroxy-3-[ (benzyloxycarbonyl) amino]-4- (phenylthio) butane is used in the preparation of HIV protease inhibitor streptolysin, antibacterial Streptococcus. Group: Biochemicals. Grades: Highly Purified. CAS No. 194086-27-6. Pack Sizes: 5mg, 50mg. Molecular Formula: C18H20ClNO3S, Molecular Weight: 365.87. US Biological Life Sciences. | Worldwide |
| (2R, 3S) -1-Chloro-2-hydroxy-3-[ (benzyloxycarbonyl) amino]-4- (phenylthio) butane | (2R, 3S) -1-Chloro-2-hydroxy-3-[ (benzyloxycarbonyl) amino]-4- (phenylthio) butane is used in the preparation of HIV protease inhibitor streptolysin, antibacterial Streptococcus. Group: Biochemicals. Grades: Highly Purified. CAS No. 220365-46-8. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C18H20ClNO3S, Molecular Weight: 365.87. US Biological Life Sciences. | Worldwide |
| (2R,4R,5S)-Lopinavir | (2R,4R,5S)-Lopinavir is a diastereomer of Lopinavir (L469480); a selective HIV protease inhibitor and antiviral. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C37H48N4O5, Molecular Weight: 628.799999999999. US Biological Life Sciences. | Worldwide |
| (2R,4S,5S)-Lopinavir | (2R,4S,5S)-Lopinavir (Lopinavir EP Impurity P) is a diastereomer of Lopinavir (L469480); a selective HIV protease inhibitor and antiviral. Group: Biochemicals. Grades: Highly Purified. CAS No. 1217628-64-2. Pack Sizes: 1mg. Molecular Formula: C37H48N4O5, Molecular Weight: 628.799999999999. US Biological Life Sciences. | Worldwide |
| (2S,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane | (2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane is an intermediate in the synthesis of Atazanavir, a novel azapeptide HIV protease inhibitor used as an antiviral agent. Synonyms: threo-N-Boc-D-phenylalanine epoxide; 2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate; (2S,3R)-3-phenylproline; trans-3-phenyl-l-proline; tert-butyl [(2R,3S)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate; (2S)-[1'(R)-Boc-amino-2'-phenylethyl]oxirane; trans-3-phenyl-(S)-proline. Grades: ≥ 95%. CAS No. 156474-22-5. Molecular formula: C15H21NO3. Mole weight: 263.33. | |
| (2S, 3S) -1-Chloro-2-hydroxy-3-[ (benzyloxycarbonyl) amino]-4- (phenylthio) butane | (2S, 3S) -1-Chloro-2-hydroxy-3-[ (benzyloxycarbonyl) amino]-4- (phenylthio) butane is used in the preparation of HIV protease inhibitor streptolysin, antibacterial Streptococcus. Group: Biochemicals. Grades: Highly Purified. CAS No. 220365-47-9. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C18H20ClNO3S, Molecular Weight: 365.87. US Biological Life Sciences. | Worldwide |
| (2S, 3S) -3-Amino-4-phenyl-1- ( (E) -1- (4- (pyridin-2-yl) benzyl) -2- (4- (pyridin-2-yl) benzylidene) hydrazinyl) butan-2-ol | (2S, 3S) -3-Amino-4-phenyl-1- ( (E) -1- (4- (pyridin-2-yl) benzyl) -2- (4- (pyridin-2-yl) benzylidene) hydrazinyl) butan-2-ol is an impurity of Atazanavir (A790051), a novel azapeptide HIV protease inhibitor (PI). Antiviral. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C34H33N5O, Molecular Weight: 527.66. US Biological Life Sciences. | Worldwide |
| (2S,4R,5S)-Lopinavir | (2S,4R,5S)-Lopinavir (Lopinavir EP Impurity N) is a diastereomer of Lopinavir (L469480); a selective HIV protease inhibitor and antiviral. Group: Biochemicals. Grades: Highly Purified. CAS No. 1798014-18-2. Pack Sizes: 1mg, 10mg. Molecular Formula: C37H48N4O5, Molecular Weight: 628.799999999999. US Biological Life Sciences. | Worldwide |
| 2-Thiocresol | 2-Thiocresol performs a fungicidal and inhibitory activity against Histoplasma capsulatum. Reagent for molecular modeling and preparation of 4-hydroxy-5,6-dihydropyrones as inhibitors of HIV protease. Group: Biochemicals. Grades: Highly Purified. CAS No. 137-06-4. Pack Sizes: 5g, 25g. Molecular Formula: C7H8S, Molecular Weight: 124.2. US Biological Life Sciences. | Worldwide |
| 2- (Trimethylstannyl) pyridine | 2- (Trimethylstannyl) pyridine is a useful synthetic intermediate. It is used to prepare L-mannonic acid derivatives as HIV-1 protease inhibitors. It is also used to synthesize aryl indole NK1 receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 13737-05-8. Pack Sizes: 1g, 10g. Molecular Formula: C8H13NSn, Molecular Weight: 241.91. US Biological Life Sciences. | Worldwide |
| 3-Amino-2-bromobenzoic Acid | 3-Amino-2-bromobenzoic Acid acts as HIV protease inhibitor. 3-Amino-2-bromobenzoic Acid is a derivative of Benzoic Acid (B203900). Benzoic Acid is used in the synthesis of selective human A3 adenosine receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 168899-61-4. Pack Sizes: 1g, 2.5g. Molecular Formula: C7H6BrNO2, Molecular Weight: 216.03. US Biological Life Sciences. | Worldwide |
| 3-(Hydroxymethyl)phenylboronic acid | Reactant involved in: Copper-mediated trifluoromethylation Copper-catalyzed transformations from arylboronic acids in water Mitsunobu, Suzuki, and amidation reactions with hydroxyphenylamino bromopyrazinecarboxylateReactant involved in the synthesis of biologically active molecules including: Mycobacterium tuberculosis H37Rv chorismate mutase inhibitors via Suzuki coupling reactions HIV protease inhibitors with antiviral activity against drug-resistant viruses Pyrrole derivatives for use as PDE4B inhibitors. Synonyms: 3-Boronobenzyl alcohol; 3-hydroxymethylbenzeneboronic acid; 3-hydroxymethylboronic acid; RARECHEM AH PB 0189; 3-HydroMethylphenylboronicacid; KS-000000LJ; m-(Hydroxymethyl)phenyl boronic acid. Grades: 97%. CAS No. 87199-15-3. Molecular formula: C7H9BO3. Mole weight: 151.96. | |
| (3R,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ol | (3R,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ol is an intermediate in the preparation of HIV-1 Protease Inhibitor. It is an isomeric impurity of Bisfuranol. Synonyms: (3aalpha,6aalpha)-Hexahydrofuro[2,3-b]furan-3alpha-ol. Grades: > 95%. CAS No. 252873-00-0. Molecular formula: C6H10O3. Mole weight: 130.14. | |
| (3R,4R)-3,4-Difluoro-1-(phenylmethyl)-L-proline methyl ester | (3R,4R)-3,4-Difluoro-1-(phenylmethyl)-L-proline methyl ester is an active metabolic intermediate in the synthesis of antiviral drugs. It is majorly used in the production of HIV protease inhibitors that effectively combat the symptoms and progression of HIV and AIDS. CAS No. 1701465-43-1. Molecular formula: C13H15F2NO2. Mole weight: 255.26. | |
| (3S, 4aS, 8aS) -2- [ (2R, 3S) -3-tert-Butyl oxycarbonyl amin o-2- hydroxy-4-phenyl butyl ] -N- (1, 1-di methyl ethyl ) dec a hydro-3-isoquinolinecarboxamid e | Intermediate in the preparation of HIV-1 protease inhibitors. Group: Biochemicals. Alternative Names: N- [ (1S, 2R) -3- [ (3S, 4aS, 8aS) -3- [ [ (1, 1-Dimethylethyl) amino] carbonyl] octahydro-2 (1H) -isoquinolinyl] -2-hydroxy-1- (phenylmethyl) propyl] -carbamic Acid 1,1-Dimethylethyl Ester; [3S-[2(1R*, 2S*), 3α, 4a β,8a β ] ] -3- [3- [ [ (1, 1-Dimethylethyl) amino] carbonyl] octahydro-2 (1H) -isoquinolinyl] -2-hydroxy-1- (phenylmethyl) propyl] -carbamic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 142580-65-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| (3S,4R)-3-(Hydroxymethyl)-3,4-pyrrolidinediol | (3S,4R)-3-(Hydroxymethyl)-3,4-pyrrolidinediol is a salient intermediate integral to bioactive compound construction. In particular, the production of HIV protease inhibitors can leverage this compound, thereby forging a pathway toward effective HIV infection treatment. Synonyms: isoDAB; (3S,4R)-3-(hydroxymethyl)-3,4-Pyrrolidinediol. CAS No. 1241760-33-7. Molecular formula: C5H11NO3. Mole weight: 133.15. | |
| 3-Tert-Butyldimethylsilyl-2-propyn-1-ol | 3-Tert-Butyldimethylsilyl-2-propyn-1-ol, a widely used chemical compound in organic synthesis, serves as a safeguarding agent for alcohols, impeding undesired chemical reactions. It displays versatility in various applications ranging from stable protecting group synthesis to the development of potent drugs such as Atazanavir, a prominent HIV protease inhibitor. The compound's multifunctional competence and adaptability make it an indispensable component of organic synthesis. Synonyms: 3-(tert-butyldimethylsilyl)-2-propyn-1-ol. Grades: 95%. CAS No. 120789-51-7. Molecular formula: C9H18OSi. Mole weight: 170.32. | |
| 4,5-Dehydro(pyrimidin-2(1H)-one) Lopinavir | 4,5-Dehydro(pyrimidin-2(1H)-one) Lopinavir is an impurity of Lopinavir, a selective HIV protease inhibitor and antiviral. Synonyms: (S)-N-((2S,4S,5S)-5-(2-(2,6-Dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxo-2,3-dihydropyrimidin-1(6H)-yl)butanamide; Lopinavir Impurity. Grades: > 95%. Molecular formula: C37H46N4O5. Mole weight: 626.78. | |
| 4-Bromobenzoyl Chloride | 4-Bromobenzoyl Chloride is used in the synthesis HIV-1 protease inhibitors. Also used in the synthesis of oxazoles and cyclohexanone derivatives as analgesic and antimicrobial agents. Group: Biochemicals. Alternative Names: p-Bromobenzoyl Chloride; 4-Bromo-1-benzenecarbonyl Chloride; 4-Bromobenzoyl Chloride; NSC 7091; p-Bromobenzoyl Chloride. Grades: Highly Purified. CAS No. 586-75-4. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| 4-Dehydroxy-5-hydroxy Ritonavir | 4-Dehydroxy-5-Hydroxy Ritonavir is an impurity of the selective HIV protease inhibitor Ritonavir. Group: Biochemicals. Alternative Names: (3S,5S,6S,9S)-5-Hydroxy-12-methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic Acid 5-Thiazolylmethyl Ester; Ritonavir Impurity I;(5S,8S,9S,11S)-9-Hydroxy-2-methyl-5-(1-methylethyl)-1-[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic Acid 5-Thiazolylmethyl Ester. Grades: Highly Purified. CAS No. 202816-62-4. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 4-Hydroxycoumarin | 4-Hydroxycoumarin, a coumarin derivative, is one of the most versatile heterocyclic scaffolds and is frequently applied in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin derivatives are employed as the anticoagulant, antibacterial, antifungal, antiviral, antitumor, antiprotozoal, insecticidal, antimycobacterial, antimutagenic, antioxidant, anti-inflammatory agents, HIV protease inhibitors and tyrosine kinase inhibitors. Group: Inhibitors. Alternative Names: Coumarinol. CAS No. 1076-38-6. Molecular formula: C9H6O3. Mole weight: 162.14. Appearance: Beige powder. Purity: 0.98. IUPACName: 4-Hydroxychromen-2-one. Canonical SMILES: C1=CC=C2C(=C1)C(=CC(=O)O2)O. Density: 1.1734 g/cm³. Catalog: ACM1076386. | |
| 4-Hydroxycoumarin | 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 1076-38-6. Pack Sizes: 10 mM * 1 mL; 50 g. Product ID: HY-N6856. |  |
| 4-Hydroxycoumarin (Standard) | 4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin. This product is intended for research and analytical applications. 4-Hydroxycoumarin is an orally active coumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 1076-38-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N6856R. | |
| Acetylpepstatin | Acetylpepstatin is an aspartyl protease inhibitor that is effective against HIV-1 and HIV-2 protease. Synonyms: Acetyl pepstatin; Acetyl-pepstatin. Grades: 95%. CAS No. 28575-34-0. Molecular formula: C31H57N5O9. Mole weight: 643.81. | |
| Acetyl Pepstatin | Acetyl Pepstatin is a high affinity HIV-1 protease inhibitor and aspartic protease inhibitor. It inhibits HIV-1 protease with Ki value of 20 nM at pH 4.7 and HIV-2 protease with Ki value of 5 nM at pH 4.7. It is used as an antiviral agent. Synonyms: Ac-Pepstatin; [1S-[1R*,2R*,4[R*[R*(R*)]]]]-1-(2-Methylpropyl)-4-oxobutyl]-N-acetyl-L-valyl-N-[4-[[2-[[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]amino]-1-methyl-2-oxoethyl]amino]-2-hydroxy-L-valinamide; Pepsin Inhibitor S-PI-D (8CI); N-Acetyl-L-valyl-L-valyl-(3S,4S)-4-amino-3-hydroxy-6- methylheptanoyl-N-[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]-L-alaninamide; Pepsidin C; S-PI; (4S,7S,8S,10S,19S)-8-carbamoyl-11,19-dihydroxy-10,18-diisobutyl-4-isopropyl-7,15-dimethyl-2,5,13,16-tetraoxo-3,9,14,17-tetraazahenicosan-21-oic acid. Grades: >98%. CAS No. 11076-29-2. Molecular formula: C31H57N5O9. Mole weight: 643.81. | |
| Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 | Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 is an HIV-1 protease inhibitor whose sequence is derived from the cleavage site of the viral gag-pol poly-protein. Electron density studies have shown that this inhibitor binds to the active site of the HIV-1 protease. Synonyms: MVT-101; N-acetyl-Thr-Ile-Nle-psi(CH2-NH)-Nle-Gln-Arg-amide; N-acetyl-threonyl-isoleucyl-norleucyl-psi(CH2-NH)-norleucyl-glutaminyl-argininamide; N-{(2S)-2-[(N-Acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-L-argininamide; L-Argininamide, N-[(2S)-2-[[(2S,3S)-2-[[(2S,3R)-2-(acetylamino)-3-hydroxy-1-oxobutyl]amino]-3-methyl-1-oxopentyl]amino]hexyl]-L-norleucyl-L-glutaminyl-. Grades: 95%. CAS No. 128657-47-6. Molecular formula: C35H67N11O8. Mole weight: 769.98. | |
| Amidosulfonic Acid | Amidosulfonic acid is mainly a precursor to sweet-tasting compounds. It has been used in the design of many types of therapeutic agents such as antibiotics, nucleoside/nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anti-cancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), anti-epileptic drugs, and weight loss drugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 5329-14-6. Pack Sizes: 1g, 10g. Molecular Formula: H3NO3S. US Biological Life Sciences. | Worldwide |
| Amprenavir | Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 1.09 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-478. CAS No. 161814-49-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17430. | |
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