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An important intermediate in corticosteroid biogenesis. Group: Biochemicals. Alternative Names: 5-Cholestene-3B,20a-diol. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC 50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 20α-Hydroxycholesterol. CAS No. 516-72-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12316.
20(S)-Hydroxycholesterol
20(S)-Hydroxycholesterol. Group: Biochemicals. Grades: Purified. CAS No. 516-72-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
20(S)-Hydroxycholesterol
20(S)-Hydroxycholesterol is an allosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein. 20(S)-Hydroxycholesterol induces Smo accumulation in primary cilia, and also exhibits osteogenic activity and activates the liver X receptor (LXR). Synonyms: 20-hydroxycholesterol; 20alpha-Hydroxycholesterol; (20S)-20-Hydroxycholesterol; cholest-5-en-3beta,20-diol; 20S-Cholest-5-ene-3beta,20-diol; 20α-hydroxycholesterol. Grades: >99%. CAS No. 516-72-3. Molecular formula: C27H46O2. Mole weight: 402.65.
20(S)-Hydroxycholesterol (Standard)
20(S)-Hydroxycholesterol (Standard) is the analytical standard of 20(S)-Hydroxycholesterol. This product is intended for research and analytical applications. 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC 50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 20α-Hydroxycholesterol (Standard). CAS No. 516-72-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12316R.
22-Hydroxycholest-4-en-3-one
22-Hydroxycholest-4-en-3-one was found in brain of Cyp46a1-/- mouse, indicating that this oxysterol promoted dopaminergic neurogenesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 60881-76-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C27H44O2, Molecular Weight: 400.64. US Biological Life Sciences.
Worldwide
22(R)-Hydroxycholesterol
22(R)-Hydroxycholesterol (Narthesterol) is an endogenous LXR agonist. 22(R)-Hydroxycholesterol (Narthesterol) can be used for tangier disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Narthesterol. CAS No. 17954-98-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-116969.
(22S)-22-Hydroxycholest-5-en-3 β-yl Acetate
(22S)-22-Hydroxycholest-5-en-3 β-yl Acetate is an intermediate in the synthesis of 22S-metabolite of Cholesterol (C432501). Group: Biochemicals. Grades: Highly Purified. CAS No. 54604-57-8. Pack Sizes: 5mg, 50mg. Molecular Formula: C29H48O3. US Biological Life Sciences.
Worldwide
24-Hydroxycholest-4-en-3-one
24-Hydroxycholest-4-en-3-one was found in brain of Cyp46a1-/- mouse, indicating that this oxysterol promoted dopaminergic neurogenesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 61092-05-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C27H44O2, Molecular Weight: 400.64. US Biological Life Sciences.
Worldwide
24-Hydroxycholesterol
24-Hydroxycholesterol, also known as 24-OH-Chol, a natural sterol, is the main cholesterol elimination product of the brain. 24-Hydroxycholesterol is a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR, and a potent activator of the transcription factors LXR. 24-Hydroxycholesterol acts as a neurotoxin to SH-SY5Y human neuroblastoma cells which showed corresponding morphological changes: the cells became round, lost adhesion to the petri-dish, and neurite outgrowth degenerated. Synonyms: (3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-5-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; 24-hydroxycholesterol; 24S-hydroxycholesterol; cerebrosterol; cholest-5-ene-3,24-diol. CAS No. 30271-38-6. Molecular formula: C27H46O2. Mole weight: 402.65.
24-Hydroxycholesterol
24-Hydroxycholesterol is a natural sterol, which serves as a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR , and a potent activator of the transcription factors LXR. Uses: Scientific research. Group: Natural products. CAS No. 30271-38-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg. Product ID: HY-N2370.
24-hydroxycholesterol 7α-hydroxylase
A P450 heme-thiolate protein that is found in liver microsomes and in ciliary non-pigmented epithelium. The enzyme is specific for (24S)-cholest-5-ene-3β,24-diol, which is formed mostly in the brain by EC 1.14.14.25, cholesterol 24-hydroxylase. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: 24-hydroxycholesterol 7α-monooxygenase; CYP39A1; CYP39A1 oxysterol 7α-hydroxylase. Enzyme Commission Number: EC 1.14.14.26. CAS No. 288309-90-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0923; 24-hydroxycholesterol 7α-hydroxylase; EC 1.14.14.26; 288309-90-0; 24-hydroxycholesterol 7α-monooxygenase; CYP39A1; CYP39A1 oxysterol 7α-hydroxylase. Cat No: EXWM-0923.
24(R)-hydroxycholesterol
24(S)-Hydroxy cholesterol is a side-chain substituted oxysterol that is generated from the action of CYP46 on cholesterol found in the brain and plays an important role in cholesterol homeostasis. 24(R)-hydroxy Cholesterol is a synthetic enantiomer of 24(S)-hydroxy cholesterol that activates LXRα and LXRβ nuclear receptors with slightly reduced potency. Synonyms: (24R)-cholest-5-ene-3beta,24-diol; (3beta,24R)-Cholest-5-ene-3,24-diol. Grades: ≥98%. CAS No. 27460-26-0. Molecular formula: C27H46O2. Mole weight: 402.65.
24(R)-Hydroxycholesterol
24(R)-Hydroxycholesterol (24R-OHC) is a key intermediate of Tacalcitol (HY-32337) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 24R-OHC; 24R-HC; 24(R)-Cerebrosterol. CAS No. 27460-26-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-16940A.
24(S)-Hydroxycholesterol
24(S)-Hydroxycholesterol (24S-OHC), the major brain cholesterol metabolite, plays an important role to maintain homeostasis of cholesterol in the brain. 24(S)-Hydroxycholesterol (24S-OHC) is one of the most efficient endogenous LXR agonist known and is present in the brain and in the circulation at relatively high levels. 24(S)-Hydroxycholesterol (24S-OHC) is a very potent, direct, and selective positive allosteric modulator of NMDARs with a mechanism that does not overlapthat of other allosteric modulators [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 24S-OHC; 24S-HC; Cerebrosterol. CAS No. 474-73-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-16940.
24(S)-Hydroxycholesterol
(3β,24S)-Cholest-5-ene-3,24-diol is used as a biomarker in the analysis of disease. Synonyms: Cerebrosterol; Cholest-5-ene-3,24-diol; 24S-hydroxycholesterol; cholest-5-en-3beta,24S-diol; (24S)-cholest-5-ene-3beta,24-diol. Grades: > 95%. CAS No. 474-73-7. Molecular formula: C27H46O2. Mole weight: 402.65.
25/26-hydroxycholesterol 7α-hydroxylase
A P-450 (heme-thiolate) protein. Unlike EC 1.14.14.26, 24-hydroxycholesterol 7α-monooxygenase, which is specific for its oxysterol substrate, this enzyme can also metabolize the oxysterols 24,25-epoxycholesterol, 22-hydroxycholesterol and 24-hydroxycholesterol, but to a lesser extent. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: 25-hydroxycholesterol 7α-monooxygenase; CYP7B1; CYP7B1 oxysterol 7α-hydroxylase; 27-hydroxycholesterol 7-monooxygenase; 27-hydroxycholesterol 7α-hydroxylase; cholest-5-ene-3β,25-diol,NADPH:oxygen oxidoreductase (7α-hydroxylating); 25-hydroxycholesterol 7α-hydroxylase. Enzyme Commission Number: EC 1.14.14.29. CAS No. 149316-80-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0926; 25/26-hydroxycholesterol 7α-hydroxylase; EC 1.14.14.29; 149316-80-3; 25-hydroxycholesterol 7α-monooxygenase; CYP7B1; CYP7B1 oxysterol 7α-hydroxylase; 27-hydroxycholesterol 7-monooxygenase; 27-hydroxycholesterol 7α-hydroxylase; cholest-5-ene-3β,25-diol,NADPH:oxygen oxidoreductase (7α-hydroxylating); 25-hydroxycholesterol 7α-hydroxylase. Cat No: EXWM-0926.
25-Hydroxycholest-4-en-3-one
25-Hydroxycholest-4-en-3-one is a key regulatory oxysterol in the liver. Group: Biochemicals. Grades: Highly Purified. CAS No. 19897-08-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C27H44O2, Molecular Weight: 400.64. US Biological Life Sciences.
Worldwide
25-Hydroxycholest-5-en-3beta-yl acetate
25-Hydroxycholest-5-en-3beta-yl acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 25-Hydroxycholesterol 3-acetate, MolPort-001-785-908, NSC226103, CID313018, 10525-22-1. Product Category: Heterocyclic Organic Compound. CAS No. 10525-22-1. Molecular formula: C29H48O3. Mole weight: 444.69 g/mol. Purity: 0.96. IUPACName: [17-(6-hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate. Canonical SMILES: CC(CCCC(C)(C)O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC(=O)C)C)C. Density: 1.04g/cm³. ECNumber: 234-080-5. Product ID: ACM10525221. Alfa Chemistry ISO 9001:2015 Certified. Categories: EINECS 234-080-5.
25 hydroxycholesterol
25 hydroxycholesterol. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2140-46-7. Molecular Formula: C27H46O2. Mole Weight: 402.66. Catalog: APB2140467.
25-Hydroxycholesterol
25-Hydroxycholesterol (25-OHC) is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC 50 ?65 nM) and selective suppressor of IgA production by B cells. Uses: Scientific research. Group: Natural products. Alternative Names: 25-OHC. CAS No. 2140-46-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113134.
25-Hydroxycholesterol-d6
25-Hydroxycholesterol-d 6 (25-OHC-d 6 ) is the deuterium labeled 25-Hydroxycholesterol. 25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50?65 nM) and selective suppressor of IgA production by B cells[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: 25-OHC-d6. CAS No. 88247-69-2. Pack Sizes: 1 mg. Product ID: HY-113134S.
27 hydroxycholesterol. Uses: For analytical and research use. Group: Impurity standards. CAS No. 20380-11-4. Molecular Formula: C27H46O2. Mole Weight: 402.66. Catalog: APB20380114.
27-Hydroxycholesterol
27-Hydroxycholesterol (27-OHC) is a selective estrogen receptor modulator and an agonist of the liver X receptor. Uses: Scientific research. Group: Natural products. Alternative Names: 27-OHC. CAS No. 20380-11-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-N2371.
27-Hydroxycholesterol
27-Hydroxycholesterol, a desmosterol metabolite found in the brain , activates LXRα (EC50= 85 nM)and LXRβ (EC50= 71 nM) in vitro. 27-HC is also an estrogen receptor partial agonist. It suppresses β-estradiol-mediated breast cancer cell proliferation in vitro. Synonyms: cholest-(25R)-5-ene-3β,27-diol; (25R)-Cholest-5-ene-3β,26-diol; 27-OHC; 5,25R-Cholesten-3beta,26-diol; (25R)-26-Hydroxycholesterol. Grades: >99%. CAS No. 20380-11-4. Molecular formula: C27H46O2. Mole weight: 402.65.
(3α,5 β, 6α, 7α)-6-Bromo-3-[(ethoxycarbonyl)oxy]-7-hydroxycholan-24-oic Acid Methyl Ester is an intermediate in the synthesis of α-Muricholic Acid (M732750), an bile acid metabolite found in urine. Group: Biochemicals. Grades: Highly Purified. CAS No. 125112-74-5. Pack Sizes: 10mg. US Biological Life Sciences.
(3α,5 β,6 β,7α)-3-[(Ethoxycarbonyl)oxy]-6-(formyloxy)-7-hydroxycholan-24-oic Acid Methyl Ester is an intermediate in the synthesis of α-Muricholic Acid (M732750), an bile acid metabolite found in urine. Group: Biochemicals. Grades: Highly Purified. CAS No. 125112-77-8. Pack Sizes: 5mg. US Biological Life Sciences.
(3α,5 β,7α)-3-[(Ethoxycarbonyl)oxy]-7-hydroxycholan-24-oic Acid Methyl Ester is an intermediate in the synthesis of α-Muricholic Acid (M732750), an bile acid metabolite found in urine. Group: Biochemicals. Grades: Highly Purified. CAS No. 61252-49-1. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
3α-hydroxycholanate dehydrogenase (NAD+)
Also acts on other 3α-hydroxysteroids with an acidic side-chain. cf. EC 1.1.1.392, 3α-hydroxycholanate dehydrogenase (NADP+). Group: Enzymes. Synonyms: α-hydroxy-cholanate dehydrogenase; lithocholate:NAD+ oxidoreductase; 3α-hydroxycholanate dehydrogenase. Enzyme Commission Number: EC 1.1.1.52. CAS No. 9028-57-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0337; 3α-hydroxycholanate dehydrogenase (NAD+); EC 1.1.1.52; 9028-57-3; α-hydroxy-cholanate dehydrogenase; lithocholate:NAD+ oxidoreductase; 3α-hydroxycholanate dehydrogenase. Cat No: EXWM-0337.
3α-hydroxycholanate dehydrogenase (NADP+)
This bacterial enzyme is involved in the modification of secondary bile acids to form 3β-bile acids (also known as iso-bile acids) via a 3-oxo intermediate. The enzyme catalyses a reversible reaction in vitro. Also acts on related bile acids. cf. EC 1.1.1.52, 3α-hydroxycholanate dehydrogenase (NAD+). Group: Enzymes. Synonyms: α-hydroxy-cholanate dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.1.1.392. CAS No. 9028-57-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0312; 3α-hydroxycholanate dehydrogenase (NADP+); EC 1.1.1.392; 9028-57-3; α-hydroxy-cholanate dehydrogenase (ambiguous). Cat No: EXWM-0312.
3 β,5α,6 β-Trihydroxycholestane
Cholesterol analog. Useful for treatment of hyperlipemia, arteriosclerosis, diabetes, obesity. Group: Biochemicals. Alternative Names: (3 β,5α,6 β)-Cholestane-3,5,6-triol; 3 β-Hydroxycholestane-5α,6 β-diol; 5α,6 β-Dihydroxycholestanol; Cholesta-3 β,5α,6 β-triol; Cholestane-3 β,5α,6 β-triol; NSC 124751; NSC 18178. Grades: Highly Purified. CAS No. 1253-84-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
3 β,5α,6 β-Trihydroxycholestane-d7
Labeled Cholesterol analog. Useful for treatment of hyperlipemia, arteriosclerosis, diabetes, obesity. Group: Biochemicals. Alternative Names: (3 β,5α,6 β)-Cholestane-3,5,6-triol-d7; 3 β-Hydroxycholestane-5α,6 β-diol-d7; 5α,6 β-Dihydroxycholestanol-d7; Cholesta-3 β,5α,6 β-triol-d7; Cholestane-3 β,5α,6 β-triol-d7; NSC 124751-d7; NSC 18178-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
3 β-Hydroxychol-5-enoic Acid Methyl Ester
3 β-Hydroxychol-5-enoic Acid Methyl Ester is a derivative of 5-Cholenic acid-3 β-ol, an selective inhibition of cyclic AMP-dependent protein kinase. 3 β-Hydroxychol-5-enoic Acid Methyl Ester is a reactant used in the preparation of cholenoic acid based bile acids present in human biological fluids. Group: Biochemicals. Alternative Names: L 601920-0; Methyl 3 β-hydroxychol-5-en-24-oate; Methyl 3 β-hydroxychol-5-enoate; Methyl Δ5-3 β-Hydroxycholanoate; Methyl-3 β-hydroxycholenate; NSC 84140. Grades: Highly Purified. CAS No. 20231-57-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
3β-hydroxycholanate 3-dehydrogenase (NAD+)
This bacterial enzyme is involved, along with EC 1.1.1.52, 3α-hydroxycholanate dehydrogenase (NAD+), or EC 1.1.1.392, 3α-hydroxycholanate dehydrogenase (NADP+), in the modification of secondary bile acids to form 3β-bile acids (also known as iso-bile acids). The enzyme catalyses the reaction in the reduction direction in vivo. Also acts on related 3-oxo bile acids. cf. EC 1.1.1.393, 3β-hydroxycholanate 3-dehydrogenase (NADP+). Group: Enzymes. Synonyms: 3β-hydroxysteroid dehydrogenase. Enzyme Commission Number: EC 1.1.1.391. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0311; 3β-hydroxycholanate 3-dehydrogenase (NAD+); EC 1.1.1.391; 3β-hydroxysteroid dehydrogenase. Cat No: EXWM-0311.
3β-hydroxycholanate 3-dehydrogenase (NADP+)
This bacterial enzyme is involved, along with EC 1.1.1.52, 3α-hydroxycholanate dehydrogenase (NAD+), or EC 1.1.1.392, 3α-hydroxycholanate dehydrogenase (NADP+), in the modification of secondary bile acids to form 3β-bile acids (also known as iso-bile acids). The enzyme catalyses the reaction in the reduction direction in vivo. Also acts on related 3-oxo bile acids. cf. EC 1.1.1.391, 3β-hydroxycholanate 3-dehydrogenase (NAD+). Group: Enzymes. Synonyms: 3β-hydroxysteroid dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.1.1.393. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0313; 3β-hydroxycholanate 3-dehydrogenase (NADP+); EC 1.1.1.393; 3β-hydroxysteroid dehydrogenase (ambiguous). Cat No: EXWM-0313.
4β-Hydroxycholesterol
4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation [1]. Uses: Scientific research. Group: Natural products. CAS No. 17320-10-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-124265.
4β-Hydroxycholesterol-d7
4β-Hydroxycholesterol-d 7 is the deuterium labeled 4β-Hydroxy Cholesterol[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1246302-80-6. Pack Sizes: 1 mg. Product ID: HY-124265S.
Solubility:Chloroform, Dichloromethane. Group: Biochemicals. Alternative Names: 7a-Hydroxycholesterol-25,26,26,26,27,27,27-d7. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
7α,12α-Dihydroxycholest-4-en-3-one
A metabolite of Hydroxycholesterol and Hydroxysitosterol. Group: Biochemicals. Alternative Names: (7α,12α)-7,12-Dihydroxycholest-4-en-3-one; Cholest-4-ene-7α,12α-diol-3-one. Grades: Highly Purified. CAS No. 1254-03-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
7α,27-Dihydroxycholesterol
7α,27-Dihydroxycholesterol is an oxysterol characterized by its oxidized side chains and is produced through the hydroxylation of 27-Hydroxycholesterol (27-OHC); it serves as a metabolite of interest in lipidomic analyses of various pathological conditions, including neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome, and diabetes. Notably, levels of 7α,27-di-OHC decrease following lipopolysaccharide activation, and it also functions as a ligand for Epstein-Barr virus-induced gene 2 (EBI2). Additionally, 7α,27-di-OHC exists as a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC). Uses: Scientific research. Group: Signaling pathways. CAS No. 4725-24-0. Pack Sizes: 1 mg. Product ID: HY-W414548.
7α-hydroxycholest-4-en-3-one 12α-hydroxylase
A P-450 heme-thiolate protein. Requires EC 1.6.2.4, NADPH-hemoprotein reductase and cytochrome b5 for maximal activity. This enzyme is important in bile acid biosynthesis, being responsible for the balance between the formation of cholic acid and chenodeoxycholic acid. Group: Enzymes. Synonyms: 7α-hydroxy-4-cholesten-3-one 12α-monooxygenase; CYP12; sterol 12α-hydroxylase (ambiguous); HCO 12α-hydroxylase. Enzyme Commission Number: EC 1.14.18.8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0970; 7α-hydroxycholest-4-en-3-one 12α-hydroxylase; EC 1.14.18.8; 7α-hydroxy-4-cholesten-3-one 12α-monooxygenase; CYP12; sterol 12α-hydroxylase (ambiguous); HCO 12α-hydroxylase. Cat No: EXWM-0970.
7Alpha-hydroxycholestanol
7Alpha-hydroxycholestanol. Uses: Designed for use in research and industrial production. Product Category: Steroidal Compounds. CAS No. 7554-76-9. Molecular formula: C27H48O2. Mole weight: 404.67. Purity: 0.95. Product ID: ACM7554769. Alfa Chemistry ISO 9001:2015 Certified.
7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 566-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N7264.
7α-Hydroxycholesterol-d7
7α-Hydroxycholesterol-d 7 is the deuterium labeled 7α-Hydroxycholesterol. 7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 349553-94-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-N7264S.
7β-Hydroxycholesterol
7β-Hydroxycholesterol is an oxysterol that derived by the oxidation of cholesterol. 7β-hydroxycholesterol can induce cellular oxidative stress, apoptosis, and necrosis, resulting in cytotoxicity. 7β-hydroxycholesterol has antitumor activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 566-27-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-113341.
7Beta-hydroxycholesterol-25,26,26,26-27,27,27-d7
7Beta-hydroxycholesterol-25,26,26,26-27,27,27-d7. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7BETA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7;7β-Hydroxycholesterol-25,26,26,26-27,27,27-D7;(3,7)-Cholest-5-ene-3,7-diol-d7;5-Cholestene-3,7-diol-d7;7-Hydroxy Cholesterol-d7;7-Hydroxycholest-5-en-3-ol-d7;Cholest-5-ene-3,7-diol-d7. Product Category: Heterocyclic Organic Compound. CAS No. 349553-97-5. Molecular formula: C26H37D7O2. Mole weight: 395.67. Purity: 98 atom % D. Product ID: ACM349553975. Alfa Chemistry ISO 9001:2015 Certified.
A synthetic analog of calcitiol (the hormonal form of vitamin D3). Group: Biochemicals. Alternative Names: 1-alpha-hydroxycholecalcifero l, 1-alpha-Hydroxyvitamin D, Alfarol, Alpha D3, Etalpha. Grades: Highly Purified. CAS No. 41294-56-8. Pack Sizes: 1mg. US Biological Life Sciences.
(1,1-Dimethylethyl)[[(3 β,25R)-ergosta-5,24(28)-dien-3-yl]oxy]dimethyl Silane is an intermediate in the synthesis of Ostreasterol which is a marine steroid, and also a derivative compound of hydroxycholesterol (H918040), which functions as the main cholesterol elimination product of the brain and was found to be increased in serum of Alzheimer patients. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C34H60OSi. US Biological Life Sciences.
Worldwide
19-Carboxy cholesterol
19-Carboxy cholesterol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3β)-3-Hydroxycholest-5-en-19-oic Acid. Product Category: Heterocyclic Organic Compound. Appearance: White to Off-White Solid. CAS No. 26319-96-0. Molecular formula: C27H44O3. Mole weight: 416.64. Purity: 0.96. IUPACName: 2-[(3S,8S,9S,10S,13R,14S,17R)-3-hydroxy-13-methyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-10-yl]acetic acid. Canonical SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)CC(=O)O)C. Product ID: ACM26319960. Alfa Chemistry ISO 9001:2015 Certified.
19-Carboxy Cholesterol
Cholesterol derivative. A new C-19-functionalized cholesterol. Group: Biochemicals. Alternative Names: (3 β)-3-Hydroxycholest-5-en-19-oic Acid. Grades: Highly Purified. CAS No. 26319-96-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
19-Hydroxy Cholesteryl 3-Acetate
A C-19 functionalized cholesterol derivative and popular substrate for steroid biotransformations. Group: Biochemicals. Alternative Names: (3 β)-Cholest-5-ene-3,19-diol 3-Acetate; 3 β-Acetoxycholest-5-en-19-ol; 19-Hydroxycholesterol 3-Acetate; 19-Hydroxycholesterol Acetate; NSC 123342. Grades: Highly Purified. CAS No. 750-59-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
1-epi-Calcitriol
1-epi-Calcitriol. Group: Biochemicals. Alternative Names: (1b,3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol; 1-Epicalcitriol; 1b, 25-Di hydroxycholecalcife rol. Grades: Highly Purified. CAS No. 66791-71-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C27H44O3. US Biological Life Sciences.
Worldwide
22-alpha-Hydroxy Cholesterol
22α-Hydroxy Cholesterol is the 22R-metabolite of Cholesterol. 22-Hydroxycholesterol inhibits chemokine receptor activity. Synonyms: (3β,22R)-Cholest-5-ene-3,22-diol; (20S,22R)-Cholest-5-ene-3β,22-diol; (22R)-22-Hydroxycholesterol; (22R)-Cholest-5-ene-3β,22-diol; (22R)-Hydroxycholesterol; 22α-Hydroxycholesterol; Cholest-5-ene-3β,22(R)-diol; Narthesterol. Grades: > 95%. CAS No. 17954-98-2. Molecular formula: C27H46O2. Mole weight: 402.67.
22b-Hydroxy cholesterol
22b-Hydroxy cholesterol. Group: Biochemicals. Alternative Names: (3b,22S)-Cholest-5-ene-3,22-diol; (20S,22S)-Cholest-5-ene-3b,22-diol; (22S)-22-Hydroxycholesterol. Grades: Highly Purified. CAS No. 22348-64-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C27H46O2. US Biological Life Sciences.
Worldwide
22(S)-Hydroxy cholesterol
22(S)-Hydroxy cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). Synonyms: cholest-5-ene-3β,22(S)-diol; 22(S)-Hydroxycholesterol; 5-cholestene-3β,22-diol; 22-hydroxycholest-5-en-3-ol; 22β-Hydroxy Cholesterol; (3β,22S)-Cholest-5-ene-3,22-diol; (20S,22S)-Cholest-5-ene-3β,22-diol; (22S)-22-Hydroxycholesterol; (22S)-Cholest-5-ene-3β,22-diol; (22β)-Hydroxycholesterol; Narthesterol. Grades: ≥95%. CAS No. 22348-64-7. Molecular formula: C27H46O2. Mole weight: 402.65.
25-Hydroxy Cholesterol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3β)-Cholest-5-ene-3,25-diol. Appearance: White to Off-White Solid. CAS No. 2140-46-7. Molecular formula: C27H46O2. Mole weight: 402.65. Product ID: ACM2140467. Alfa Chemistry ISO 9001:2015 Certified. Categories: 25-Hydroxycholesterol.
25-Hydroxy-Cholesterol
25-hydroxycholesterol is an inhibitor of human immunodeficiency virus replication in vitro. It induces apoptosis in human monocytic cell lines as well as in CEM cells associated with negative regulation of c-Myc. Synonyms: (3β)-Cholest-5-ene-3,25-diol; Cholest-5-ene-3β,25-diol; 25-Hydroxy-5-cholestene-3β-ol; 5-Cholesten-3β,25-diol. Grades: >98%. CAS No. 2140-46-7. Molecular formula: C27H46O2. Mole weight: 402.65.
25-Hydroxyprovitamin D3
25-Hydroxyprovitamin D3 is a derivative of vitamin D3 and an impurity of calcifediol. Calcifediol is a prehormone produced in the liver from vitamin D3. Synonyms: Calcifediol EP Impurity B; 25-Hydroxy-7-dehydrocholesterol; cholesta-5,7-diene-3β,25-diol; 7-Dehydro-25-hydroxycholesterol. CAS No. 22145-68-2. Molecular formula: C27H44O2. Mole weight: 400.645.
25-Hydroxy Vitamin D3 3,3-Aminopropyl Ether
Vitamin D3 analog. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),[1] is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.[2] At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days.[3] Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation.[4][5]. Group: Biochemicals. Alternative Names: ( ε R, 1R, 3aS, 4E, 7aR) -4- [ (2Z) -2- [ (5S) -5- (3-Aminopropoxy) -2- methyl enecyclohexylidene] ethylidene] octahydro- α , α , ε , 7a-tetra methyl -1H-indene-1-pentanol; (3 β,5Z,7E)-3-(3-Aminopropoxy)-9,10-secocholesta-5,7,10(19)-trien-25-ol; 3-O-(2-Aminoethyl)-25-hydroxyvitamin D3. Grades: Highly Purified. CAS No. 163018-26-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
25-Hydroxyvitamin D3 3-Hemisuccinate
25-Hydroxyvitamin D3 3-Hemisuccinate is a conjugate of 5-Hydroxyvitamin D3 (C125700), the principal circulating form of vitamin D3, formed in the liver by hydroxylation at C-25. Calcium regulator. Also used in the preparation and synthesis of antisera to be used in the immunoassay of 25-Hydroxyvitamin D3. Group: Biochemicals. Alternative Names: (3 β,5Z,7E)-3-(Hydrogen Butanedioate)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol; 25-Hydroxycholecalciferol-3-hemisuccinate; Calcidiol 3-Hemisuccinate. Grades: Highly Purified. CAS No. 69511-19-9. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
25-Hydroxyvitamin D3 3-Hemisuccinate
25-Hydroxyvitamin D3 3-Hemisuccinate is a conjugate of 5-Hydroxyvitamin D3. Synonyms: (3β,5Z,7E)- 3-(Hydrogen Butanedioate)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol; 25-Hydroxycholecalciferol-3-hemisuccinate; Calcidiol 3-Hemisuccinate. CAS No. 69511-19-9. Molecular formula: C31H48O5. Mole weight: 500.71.
25-Hydroxyvitamin D3 3-Hemisuccinate-13C4
25-Hydroxyvitamin D3 3-Hemisuccinate-13C4. Group: Biochemicals. Alternative Names: (3 β,5Z,7E)-3-(Hydrogen Butanedioate)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol-13C4; 25-Hydroxycholecalciferol-3-hemisuccinate-13C4; Calcidiol 3-Hemisuccinate-13C4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C2713C4H48O5, Molecular Weight: 504.68. US Biological Life Sciences.
Worldwide
25-Hydroxy Vitamin D3 3-Sulfate Sodium Salt
25-Hydroxyvitamin D3 3-Sulfate is a metabolite of 24,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days. Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation. Group: Biochemicals. Alternative Names: (3 β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol 3-(Hydrogen Sulfate) Sodium Salt; 25-Hydroxyvitamin D3 3-Sulfate Sodium Salt; 25-Hydroxyvitamin D3 3 β-Sulfate Sodium Salt; Calcifediol 3-Sulfate Sodium Salt. Grades: Purified. Pack Sizes: 2.5mg. Molecular Formula: C??H??NaO?S, Molecular Weight: 502.68. US Biological Life Sciences.
Worldwide
25-Hydroxyvitamin D3 (Calcifediol)
A metabolite of Vitamin D. The principal circulating form of vitamin D3, formed in the liver by hydroxylation at C-25. Calcium regulator. Group: Biochemicals. Alternative Names: (3 β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol; 25-hydroxycholecalcifero l; 25-Hydroxyvitamin D; 25-Hydroxyvitamin D3; Calcidiol; Didrogyl; Hidroferol; Ro 8-8892. Grades: Highly Purified. CAS No. 19356-17-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C??H??O?, Molecular Weight: 400.64. US Biological Life Sciences.
Worldwide
25-Hydroxyvitamin D3 Monohydrate
25-Hydroxyvitamin D3 Monohydrate. Group: Biochemicals. Alternative Names: 9,10-Secocholesta-5,7,10(19)-triene-3,25-diol, monohydrate;25-Hydroxycholecalciferol monohydrate; Calcifediol monohydrate. Grades: Highly Purified. CAS No. 63283-36-3. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
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