Hydroxysteroid Suppliers USA
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Product | Description | |
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17b-Hydroxysteroid Dehydrogenase Type-3 Inhibitor (17b-HSD3 Inhibitor, 5-(3-Bromo-4-hydroxybenzylidene)-3-(4-methoxyphenyl)-2-thioxothiazolidin-4-one) Quick inquiry Where to buy Suppliers range | A cell-permeable benzylidine-thioxothiazolidinone compound that blocks the steroidogenesis of testosterone by directly inhibiting 17b-HSD3- (17b-hydroxysteroid dehydrogenase type 3) catalyzed, NADPH-dependent, reduction of delta4-dione C17 ketone in a delta4-dione- (4-androstene-3,17-dione) competitive, highly potent (IC50=0.6, 6.0, and 40nM, respectively, against momoset, human, and mouse 17b-HSD3 activity in testes homogenate), and selective manner, displaying no activity against 17b-HSD1 and 17b-HSD2 activity. Poor pharmacokinetic properties limit its use to culture treatments and cell-free assays only. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
3Alpha-hydroxysteroid dehydrogenase Quick inquiry Where to buy Suppliers range | ammonium sulfate suspension. Group: Main Products. Alternative Names: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE;3ALPHA-HYDROXYSTEROID: NAD[P]+ OXIDOREDUCTASE;EC 1.1.1.50;EC: 1.1.1.50;3alpha-hydroxysteroid dehydrogenase F. pseu. test. ~9 U/mg;3alpha-Hydroxysteroid Dehydrogenase from Pseudomonas testosteroni;Dehydrogenase, 3alpha-hydroxy steroid;HYDROXYSTEROID OXIDOREDUCTASE. Grades: ≥50units/mg protein. CAS No. 9028-56-2. Mole weight: 0. | |
Inactive hydroxysteroid dehydrogenase-like protein 1 (20-27) Quick inquiry Where to buy Suppliers range | Inactive hydroxysteroid dehydrogenase-like protein 1. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-210. | |
11beta-Hydroxyprogesterone Quick inquiry Where to buy Suppliers range | 11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase and can confer mineralocorticoid activity on corticosterone in the rat in vivo. 11beta-Hydroxyprogesterone also activates human mineralocorticoid receptor in COS-7 cells with anED50of 10 nM. Synonyms: (8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one; 11OHP compound; Duralutin; Gesterol; Hy-Gestrone; Hylutin; Hyprogest; Pergestron; pregn-4-ene-11 beta-ol-3,20-dione; Pro-Depo; Prodrox; 11β-Hydroxyprogesterone. CAS No. 600-57-7. Molecular formula: C21H30O3. Mole weight: 330.46. | |
11-Dehydrocorticosterone (17-α, β Mixture) Quick inquiry Where to buy Suppliers range | 11-Dehydrocorticosterone (α, β mixture) is a precursor to corticosterone (C695700), converted by 11 β-hydroxysteroid dehydrogenase type 1 (11 β-HSD1) which plays a role in glucocorticoid-induced insulin resistance. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C21H28O4. US Biological Life Sciences. | Worldwide |
1H-Indazole-6-boronic Acid Quick inquiry Where to buy Suppliers range | It is commonly used in the preparation of reactants such as dicyclic hydroxybenzophenone derivatives as hydroxysteroid dehydrogenase inhibitors. Synonyms: 6-Indazolyboronic acid; 1H-Indazol-6-yl-6-boronic acid; (1H-indazol-6-yl)boronic acid; Indazole-6-boronic acid; Boronic acid, 1H-indazol-6-yl-; MFCD04972419; J-500188; (2H-indazol-6-yl)boronic acid; AMBA00083; CTK5G0023. Grades: > 97 % (HPLC). CAS No. 885068-10-0. Molecular formula: C7H7BN2O2. Mole weight: 161.95. | |
2,3-Difluoropyridine Quick inquiry Where to buy Suppliers range | 2,3-Difluoropyridine is an intermediate used in the preparation of 2,7-diazaspiro[4.5]decan-1-one derivatives as 11- β hydroxysteroid dehydrogenase type 1 inhibitors and mineralocorticoid receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 1513-66-2. Pack Sizes: 10g, 25g. Molecular Formula: C5H3F2N. US Biological Life Sciences. | Worldwide |
2,4-Bis(4-methyl-1-piperazinyl)-3H-1,5-benzodiazepine Quick inquiry Where to buy Suppliers range | Non-steroidal inhibitor of fungal 17 β-hydroxysteroid dehydrogenase. Group: Biochemicals. Grades: Highly Purified. CAS No. 733811-07-9. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
2- (9-Bromononyloxy) tetrahydropyran Quick inquiry Where to buy Suppliers range | 2- (9-Bromononyloxy) tetrahydropyran is a useful synthetic intermediate. It is used to prepare estradiol-adenosine hybrid compounds designed to inhibit type 1 17 β-hydroxysteroid dehydrogenase. It can be also used to prepare biphenylsulfonates as S1P1 receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 55695-90-4. Pack Sizes: 1g, 10g. Molecular Formula: C14H27BrO2, Molecular Weight: 307.27. US Biological Life Sciences. | Worldwide |
2-(Azetidin-1-yl)ethanol Quick inquiry Where to buy Suppliers range | 2-(Azetidin-1-yl)ethanol is used to prepare novel proline and morpholine derivatives as inhibitors of 11- β-hydroxysteroid dehydrogenase type 1 (11- β-hsd-1) for treatment of diabetes and obesity. It is also used in the synthesis of antitumor dibenzonaphthyridine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 67896-18-8. Pack Sizes: 100mg, 1g. Molecular Formula: C5H11NO, Molecular Weight: 101.15. US Biological Life Sciences. | Worldwide |
2-Bromo-5-chlorotoluene Quick inquiry Where to buy Suppliers range | 2-Bromo-5-chlorotoluene is a reagent used in the synthesis of morpholylureas as a new class of potent and selective inhibitors of the type 5 17- β-hydroxysteroid dehrydogenase (AKR1C3) (1). 2-Bromo-5-chlorotoluene is also used as a reagent in the synthesis of a series of aminopiperidines as novel iNOS inhibitors (2). Group: Biochemicals. Grades: Highly Purified. CAS No. 14495-51-3. Pack Sizes: 1g, 10g. Molecular Formula: C7H6BrCl, Molecular Weight: 205.48. US Biological Life Sciences. | Worldwide |
2-Fluoro-3-Methoxyphenylboronic acid Quick inquiry Where to buy Suppliers range | 2-Fluoro-3-methoxyphenylboronic acid was used as the reactant to participate in the regional selective suzuki coupling, the preparation of 17 hydroxysteroid dehydrogenase type 1 inhibitors, and the preparation of boron esters. Synonyms: 2-fluoro-3-methoxybenzeneboronic acid; Boronic acid, (2-fluoro-3-methoxyphenyl)-; MFCD02094728; 2-fluoro-3-methoxy-phenyl-boronic acid; AK-34813; BC000799. Grades: 98 % (HPLC). CAS No. 352303-67-4. Molecular formula: C7H8BFO3. Mole weight: 169.95. | |
2-(Methylthio)imidazole Quick inquiry Where to buy Suppliers range | 2-(Methylthio)imidazole is used as a reagent in the synthesis of 4-Methyl-5-phenyl-(1,2,4)-triazoles as selective inhibitors of 11 β-hydroxysteroid dehydrogenase type I (11 β-HSD1). Group: Biochemicals. Grades: Highly Purified. CAS No. 7666-4-8. Pack Sizes: 500mg, 5g. Molecular Formula: C4H6N2S, Molecular Weight: 114.17. US Biological Life Sciences. | Worldwide |
3-Amino-3-methylbutanoic Acid, 90% Quick inquiry Where to buy Suppliers range | 3-Amino-3-methylbutanoic Acid acts as a reagent in the preparation of arylsulfonyl methylbutanamides of cycloalkylamines, particularly adamantylamines, as selective inhibitors of human and murine 11 β-hydroxysteroid dehydrogenase type 1. Synthesis of acetylcholine and carbamoylcholine analogs as a functionally selective α4 β2 nicotinic acetylcholine receptor agonist. Phenamide preparation by coupling reaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 625-05-8. Pack Sizes: 250mg, 1g. Molecular Formula: C5H11NO2. US Biological Life Sciences. | Worldwide |
3-Bicyclo[3.2.1]octanone Quick inquiry Where to buy Suppliers range | 3-Bicyclo[3.2.1]octanone is used as a reactant in the synthesis of polycyclic acid derivatives as selective inhibitors of human 11 β-hydroxysteroid dehydrogenase type 1 (11 β-HSD-1). Group: Biochemicals. Grades: Highly Purified. CAS No. 14252-05-2. Pack Sizes: 250mg, 2.5g. Molecular Formula: C8H12O, Molecular Weight: 124.18. US Biological Life Sciences. | Worldwide |
3-Bromobenzoic Acid Methyl Ester-d4 Quick inquiry Where to buy Suppliers range | 3-Bromobenzoic Acid Methyl Ester-d4, is the labeled analogue of 3-Bromobenzoic Acid Methyl Ester (B680250), an halogenated benzoate derivative used as a reagent in organic synthesis. 3-Bromobenzoic Acid Methyl Ester is used in the synthesis of a novel series of tetra hydrodibenzazocine as inhibitors of 17 β-hydroxysteroid dehydrogenase type 3. Group: Biochemicals. Grades: Highly Purified. CAS No. 1643575-37-4. Pack Sizes: 100mg, 500mg. Molecular Formula: , Molecular Weight: US Biological Life Sciences. | Worldwide |
5α-Cholestan-3 β-ol Quick inquiry Where to buy Suppliers range | 5α-Cholestan-3 β-ol is a carbon stanol formed from biohydrogenation of Cholesterol (C432501) in the gut. Studies have also examined the conversion of 5α-Cholestan-3 β-ol catalyzed by 3- β-hydroxysteroid dehydrogenase of rat liver. Group: Biochemicals. Alternative Names: (3 β,5α)-Cholestan-3-ol; 3 β-Hydroxy-5α-cholestane; 3 β-Hydroxycholestane; 5α(H)-Cholestan-3 β-ol; 5α-Cholestanol; 5α-Dihydrocholesterol; Cholestan-3 β-ol; Cholestanol; Dihydrocholesterin; Dihydrocholesterol; Dihydrolathosterol; Lathostanol; NSC 18188; Zymostanol; β-Cholestanol. Grades: Highly Purified. CAS No. 80-97-7. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
7α,12α-Dihydroxy-5 β-cholestan-3-one Quick inquiry Where to buy Suppliers range | Substrate for 3α-Hydroxysteroid Dehydrogenase in primary bile acid biosynthesis. Group: Biochemicals. Alternative Names: (5 β, 7α, 12α)-7, 12-Dihydroxy-cholestan-3-one. Grades: Highly Purified. CAS No. 547-97-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
AKR1C1 Inhibitor, 5-PBSA Quick inquiry Where to buy Suppliers range | A cell-permeable salicylic acid compound that acts as a highly potent, active-site directed and substrate competitive AKR1C1 inhibitor (Ki=4nM) with moderate to excellent selectivity over AKR1C2, AKR1C3 and AKR1C4 (Ki=0.087, 4.2 and 18.2uM, respectively). Shown to inhibit the metabolism of progesterone by AKR1C1 (IC50=460nM in AKR1C1 overexpressing BAECs).CAS No.4906-68-7. Group: Biochemicals. Alternative Names: Aldo-Keto Reductase family 1 member C1 Inhibitor, 5-PBSA, 3-Bromo-5-phenylsalicylic acid, 20α-Hydroxysteroid Dehydrogenase Inhibitor, 5-PBSA. Grades: Highly Purified. CAS No. 4906-68-7. Pack Sizes: 25mg. Molecular Formula: C??H?BrO?. US Biological Life Sciences. | Worldwide |
AKR1C3 Inhibitor (3- (4- (Trifluoromethyl) phenylamino) benzoic Acid) Quick inquiry Where to buy Suppliers range | A cell-permeable 3-phenyl-aminobenzoate compound that acts as a potent, competitive, reversible, active-site targeting inhibitor of aldo-keto reductase 1C3 (AKR1C3; type 5 17b-hydroxysteroid dehydrogenase) (IC50 = 60nM) with excellent selectivity over other closely related human AKR isoforms (IC50 = 22.7, 15.4, 62.7, >50, and >50uM for and AKR1C1, AKR1C2, AKR1C4, AKR1B1 and AKR1B10, respectively. Exhibits a weak inhibitory effect on cyclooxygenase 1 and 2 (IC50 = 100uM). Shown to efficiently block the AKR1C3-mediated production of testosterone in LNCaP-AKR1C3 cells (~10uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Antibiotic 0231A Quick inquiry Where to buy Suppliers range | It is a 3-α-hydroxysteroid dehydrogenase inhibitor produced by the strain of Strptomyces sp. HKI 0231. It can inhibit 3-α-hydroxysteroid dehydrogenase with IC50 of 10.5 μg/mL. It has weak antimicrobial and antifungal activity (MIC is less than 100 μg/mL). Synonyms: 0231A; Benz[cd]isoindolo[2,1-a]indol-1(8H)-one, 8,8,9-trimethoxy-5-methyl-. CAS No. 357924-11-9. Molecular formula: C22H19NO4. Mole weight: 361.39. | |
Antibiotic 0231B Quick inquiry Where to buy Suppliers range | It is a 3-α-hydroxysteroid dehydrogenase inhibitor produced by the strain of Strptomyces sp. HKI 0231. It can inhibit 3-α-hydroxysteroid dehydrogenase with IC50 of 2.5 μg/mL. It has weak antimicrobial and antifungal activity (MIC is less than 100 μg/mL). Synonyms: 0231B; Benz[cd]isoindolo[2,1-a]indol-1(8H)-one, 8,9-dimethoxy-5-methyl-. CAS No. 357924-12-0. Molecular formula: C21H17NO3. Mole weight: 331.36. | |
ASP-9521 Quick inquiry Where to buy Suppliers range | ASP9521 is a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3). ASP9521 has demonstrated anti-tumour activity in in vitro and in vivo preclinical models. ASP9521 inhibited conversion of androstenedione (AD) into testosterone (T) by recombinant human or cynomolgus monkey AKR1C3 in a concentration-dependent manner. Synonyms: ASP9521; ASP-9521; ASP 9521. AKR1C3 inhibitor ; 17HSD5 inhibitor;4-(2-Hydroxy-2-methylpropyl)piperidino(5-methoxy-1H-indole-2-yl)methanone; 1-[1-[(5-Methoxy-1H-indol-2-yl)carbonyl]piperidin-4-yl]-2-methylpropan-2-ol. Grades: 98%. CAS No. 1126084-37-4. Molecular formula: C19H26N2O3. Mole weight: 330.428. | |
AZD4017 Quick inquiry Where to buy Suppliers range | AZD4017 is a potent, selective, and orally bioavailable 11β-HSD1 inhibitor (11β-hydroxysteroid dehydrogenase type 1 inhibitor). Inhibition of 11β-HSD1 is an attractive mechanism for the treatment of obesity and other elements of the metabolic syndrome. Synonyms: AZD-4017; AZD 4017; (S)-2-(1-(5-(Cyclohexylcarbamoyl)-6-(propylthio)pyridin-2-yl)piperidin-3-yl)acetic acid. Grades: 96%. CAS No. 1024033-43-9. Molecular formula: C22H33N3O3S. Mole weight: 419.58. | |
AZD8329 Quick inquiry Where to buy Suppliers range | AZD8329 is a potent, selective 11β-HSD1 inhibitor (11β-hydroxysteroid dehydrogenase type 1 inhibitor) with reduced acyl glucuronide liability. AZD8329 demonstrates to have improved technical profile in terms of both solubility and pharmacokinetics. The extent of acyl glucuronidation was reduced through structural optimization of both the carboxylic acid and amide substituents, coupled with a reduction in lipophilicity leading to an overall increase in metabolic stability. Synonyms: AZD-8329; AZD 8329; 4-(4-((1r,3r,5r,7r)-adamantan-2-ylcarbamoyl)-5-(tert-butyl)-1H-pyrazol-1-yl)benzoic acid. Grades: 98%. CAS No. 1048668-70-7. Molecular formula: C25H31N3O3. Mole weight: 421.54. | |
BVT-14225 Quick inquiry Where to buy Suppliers range | BVT-14225 is a highly selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor(IC50 = 52 nM), which is 1,000 fold lower than that for 11β-HSD2. Synonyms: 2-[2-[(3-chloro-2-methylphenyl)sulfonylamino]-1,3-thiazol-4-yl]-N,N-diethylacetamide; BVT-14225; BVT 14225; BVT14225. CAS No. 376638-65-2. Molecular formula: C16H20ClN3O3S2. Mole weight: 401.93. | |
BVT 2733 Quick inquiry Where to buy Suppliers range | BVT 2733 is a non-steroidal small molecule as a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC = 96 ± 14 nM). Synonyms: BVT-2733; BVT 2733; BVT2733; 3-chloro-2-methyl-N-(4-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)thiazol-2-yl)benzenesulfonamide; Piperazine, 1-((2-(((3-chloro-2-methylphenyl)sulfonyl)amino)-4-thiazolyl)acetyl)-4-methyl-. Grades: 98%. CAS No. 376640-41-4. Molecular formula: C17H21ClN4O3S2. Mole weight: 428.95. | |
BVT 2733 hydrochloride Quick inquiry Where to buy Suppliers range | BVT 2733 hydrochloride is a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1. Synonyms: BVT 2733 hydrochloride; BVT2733 hydrochloride; BVT-2733 hydrochloride; 3-chloro-2-methyl-N-[4-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl]benzenesulfonamide hydrochloride. Grades: 99%. CAS No. 376641-65-5. Molecular formula: C17H21ClN4O3S2.HCl. Mole weight: 465.42. | |
Carbenoxolone disodium Quick inquiry Where to buy Suppliers range | The sodium salt form of Carbenoxolone, which has been found to be an anti-inflammatory glucocorticoid and could inhibit 11β-hydroxysteroid dehydrogenase. Uses: Anti-ulcer agents. Synonyms: (3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid disodium. Grades: ≥98% by HPLC. CAS No. 7421-40-1. Molecular formula: C34H48Na2O7. Mole weight: 614.72. | |
Epostane Quick inquiry Where to buy Suppliers range | 3 β-Hydroxysteroid dehydrogenase inhibitor; a derivative of trilostane. Interceptive. Group: Biochemicals. Alternative Names: (4α,5α,17 β)-4,5-Epoxy-3,17-dihydroxy-4,17-dimethylandrost-2-ene-2-carbonitrile; Win 32729. Grades: Highly Purified. CAS No. 80471-63-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
MK0916 Quick inquiry Where to buy Suppliers range | MK0916 is an 11β-hydroxysteroid dehydrogenase type 1 inhibitor. It is used for patients with type 2 diabetes mellitus and metabolic syndrome and obesity-related disorders. It produces mechanism-based activation of the hypothalamic-pituitary-adrenal axis and results in mean increases in adrenal androgen levels that remains within the normal range. Uses: Mk0916 is used for patients with type 2 diabetes mellitus and metabolic syndrome and obesity-related disorders. Synonyms: MK 0916; MK-0916; 3-((1s,3s)-1-(4-chlorophenyl)-3-fluorocyclobutyl)-4,5-dicyclopropyl-4H-1,2,4-triazole. Grades: 98%. CAS No. 633317-53-0. Molecular formula: C18H19ClFN3. Mole weight: 331.82. | |
N- (3, 3-Diethoxypropyl) acetamide Quick inquiry Where to buy Suppliers range | N- (3, 3-Diethoxypropyl) acetamide is an intermediate used in the preparation of piperidine and homopiperidine derivatives as inhibitors of 17 β-hydroxysteroid dehydrogenase type 3 (17 β-HSD3). Group: Biochemicals. Grades: Highly Purified. CAS No. 581814-43-9. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
PF 915275 Quick inquiry Where to buy Suppliers range | PF-915275 is a selective and potent and inhibitor of human 11β-hydroxysteroid dehydrogenase type 1(11βHSD1) inhibitor with Ki 2.3 nM. It has good preclinical pharmacokinetic properties. It inhibits the conversion of prednisone to prednisolone in human hepatocytes in vitro and has antidiabetic activity in vivo. It maintains potency in our cellular assay against human 11βHSD1 and is selective against human 11βHSD2 in vitro. It displays only weak affinity for the rodent choline transporter (Ki = 9.6 μM) and the hamster melatonin MT3 receptor (Ki = 9.6 μM) in the Cerep Bioprint screening panel. It has good in vitro pharmacokinetic properties. It has low clearance and high permeability. It has an excellent pharmacokinetic profile characterized by low clearance, long half-life and good oral bioavailability. Uses: Pf-915275 inhibits the conversion of prednisone to prednisolone in human hepatocytes in vitro and has antidiabetic activity in vivo. it has an excellent pharmacokinetic profile characterized by low clearance, long half-life and good oral bioavailability. Synonyms: PF-915275; PF 915275; PF915275; N-(6-Amino-2-pyridinyl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide;N-(6-aminopyridin-2-yl)-4-(4-cyanophenyl)benzenesulfonamide;[1,1'-Bip;4'-cyanobiphenyl-4-sulfonic acid (6-aminopyridin-2-yl)amide. Grades: >98 %. CAS No. 857290-04-1. Molecular formula: C18H14N4O2S. Mole weight: 350.39. | |
TC HSD 21 Quick inquiry Where to buy Suppliers range | TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor (IC50 = 6 and 40 nM at human and mouse 17β-HSD3, respectively) with no activity at 17β-HSD1, 17β-HSD2, ERα, androgen receptors or glucocorticoid receptors. Synonyms: TC HSD 21; TC-HSD-21; TCHSD21; TC-HSD 21; 5-[(3-Bromo-4-hydroxyphenyl)methylene]-3-(4-methoxyphenyl)-2-thioxo-4-thiazolidinone. Grades: ≥99% by HPLC. CAS No. 330203-01-5. Molecular formula: C17H12BrNO3S2. Mole weight: 422.32. | |
TC HSD 21 (5-[ (3-Bromo-4-hydroxyphenyl) methylene]-3- (4-methoxyphenyl) -2-thioxo-4-thiazolidinone) Quick inquiry Where to buy Suppliers range | Potent 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3) inhibitor (IC50 values are 6 and 40nm at human and mouse 17beta-HSD3 respectively). Displays no activity at 17beta-HSD1, 17beta-HSD2, ERalpha, androgen receptors or glucocorticoid receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 330203-01-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Threonine Dehydrogenase Inhibitor, QC1 (N-Benzyl-4-oxo-2-thioxo-3- (3- (trifluoromethyl) phenyl) -1, 2, 3, 4-tetrahydroquinazoline-7-carboxamide) Quick inquiry Where to buy Suppliers range | A cell-permeable quinazolinecarboxamide (QC) compound that acts as a potent, reversible and mixed noncompetitive inhibitor of threonine dehydrogenase activity (IC50 ~ 0.5uM for mTDH) with excellent selectivity over hydroxysteroid, alcohol, lactate, or glucose-6-phosphate dehydrogenases (IC50 >10uM). Shown to block threonine catabolism, induce autophagy and impede the growth of highly proliferating mouse embryonic stem cells (mESCs; EC50 ~3uM) with no effect on ESCs-derived embryoid body cells, 3T3 fibroblasts or tumor cells (EC50 ~1 mM). Group: Biochemicals. Grades: Highly Purified. CAS No. 403718-45-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Trilostane Quick inquiry Where to buy Suppliers range | Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It is used for the treatment of pituitary-dependent adrenocortical hormone hyperplasia in dogs and the treatment of adrenocortical hormone hyperplasia caused by adrenal cortex tumors in dogs. Synonyms: WIN24540; WIN-24540; WIN 24540; Trilostane; DB01108; D-01180; D 01180; Modrastane. Desopan; Modrenal. Grades: >98%. CAS No. 13647-35-3. Molecular formula: C20H27NO3. Mole weight: 329.43. | |
Vibralactone D Quick inquiry Where to buy Suppliers range | Vibralactone D is isolated from Boreostereum vibrans and exhibits weak inhibitory effect against isozymes of 11beta-hydroxysteroid dehydrogenases (HSD). Synonyms: (1S,5R,6S)-6-hydroxy-5-(3-methylbut-2-enyl)-3-oxabicyclo[3.2.1]octan-4-one; 3-Oxabicyclo[3.2.1]octan-2-one, 7-hydroxy-1-(3-methyl-2-buten-1-yl)-, (1R,5S,7S)-. Grades: ≥98%. CAS No. 1251748-32-9. Molecular formula: C12H18O3. Mole weight: 210.27. |