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| Product | Description | |
|---|---|---|
| 2-Methyl-5-hydroxytryptamine hydrochloride | 2-Methyl-5-hydroxytryptamine hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 845861-49-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| 2-Methyl-5-hydroxytryptamine hydrochloride | 2-Methyl-5-hydroxytryptamine hydrochloride is a 5-HT3 agonist (Ki = 1200 nM) and potent 5-HT6 ligand (Ki = 46 nM). It affects the gut functions including secretion, muscle contraction and enteric nervous activity. Synonyms: 2-Me-5-HT Hydrochloride; 2-Methyl-5-HT Hydrochloride; 2-Methyl-5-hydroxytryptamine Hydrochloride; 2-Methylserotonin Hydrochloride. Grades: ≥98% by HPLC. CAS No. 845861-49-6. Molecular formula: C11H14N2O.HCl. Mole weight: 226.71. |  |
| 4-Hydroxytryptamine, Creatine Sulfate | 4-Hydroxytryptamine, Creatine Sulfate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 5-Hydroxytryptamine | 5-Hydroxytryptamine. Uses: For analytical and research use. Group: Impurity standards. CAS No. 50-67-9. Molecular Formula: C10H12N2O. Mole Weight: 176.22. Catalog: APB50679. |  |
| 5-Hydroxytryptamine 98+% | 5-Hydroxytryptamine 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| 5-Hydroxytryptamine, Creatine Sulfate | 5-Hydroxytryptamine, Creatine Sulfate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 5-Hydroxytryptamine creatine sulfate monohydrate | 5-Hydroxytryptamine creatine sulfate monohydrate. Group: Biochemicals. Alternative Names: Serotonin creatinine sulfate. Grades: Highly Purified. CAS No. 61-47-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C14H19N5O2·H2SO4·H2O. US Biological Life Sciences. | Worldwide |
| 5-Hydroxytryptamine creatinine sulfate monohydrate | 5-Hydroxytryptamine creatinine sulfate monohydrate is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 61-47-2. Pack Sizes: 100 mg. Product ID: HY-W010973. |  |
| 5-Hydroxytryptamine (Serotonin) | Serotonin also called 5-hydroxytryptamine, is primarily found in the gastrointestinal (GI) tract and central nervous system (CNS) of animals. Approximately 80 percent of the human body's total serotonin is located in the enterochromaffin cells in the gut, where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic neurons in the CNS where it has various functions, including the regulation of mood, appetite, sleep, muscle contraction, and some cognitive functions including memory and learning; and in blood platelets where it helps to regulate hemostasis and blood clotting. In addition to animals, serotonin is also found in fungi and plants. 5-hydroxytryptamine(5-HT) is an important neurotransmitter made by neurons in the central nervous system. These functions are mediated by a large number of receptors.After it is released by a neuron, 5-HT activates receptors located on nearby neurons. Group: Biochemicals. Alternative Names: 3-(2-Aminoethyl)-5-hydroxyindole; 3-(2-Amino-ethyl)-1H-indol-5-ol; Serotonin. Grades: Highly Purified. CAS No. 50-67-9. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C10H12N2O, Molecular Weight: 176.22. US Biological Life Sciences. | Worldwide |
| 6-Hydroxytryptamine creatinine sulfate | 6-Hydroxytryptamine creatinine sulfate. Group: Biochemicals. Alternative Names: 3-(2-Aminoethyl)-indol-6-ol Creatinine Sulfate. Grades: Highly Purified. CAS No. 39929-25-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C14H21N5O6S. US Biological Life Sciences. | Worldwide |
| 6-Hydroxytryptamine, Creatinine Sulfate | 6-Hydroxytryptamine, Creatinine Sulfate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| α-Methyl-5-hydroxytryptamine maleate | α-Methyl-5-hydroxytryptamine maleate, a salt of α-Methylserotonin maleate, is a 5-HT2B receptor selective agonist with pKi values of 8.4, 6.1 and 7.3 at 5-HT2B, 5-HT2A and 5-HT2C receptors respectively. It is used for forskolin-free cAMP assay for Gi-coupled receptors. Synonyms: 1H-Indol-5-ol, 3-(2-aminopropyl)-, (2Z)-2-butenedioate (1:1); 1H-Indol-5-ol, 3-(2-aminopropyl)-, (Z)-2-butenedioate (1:1) (salt); Indol-5-ol, 3-(2-aminopropyl)-, maleate; 2-Methyl-5-hydroxytryptamine maleate; 5-Hydroxy-α-methyltryptamine maleate; α-Methylserotonin maleate. Grades: ≥98% by HPLC. CAS No. 97469-12-0. Molecular formula: C11H14N2O.C4H4O4. Mole weight: 306.32. | |
| a-Methyl-5-hydroxytryptaminemaleate | a-Methyl-5-hydroxytryptaminemaleate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 304-52-9. Molecular Formula: C11H14N2O. Mole Weight: 190.25. Catalog: APB304529. | |
| N-Acetyl-5-hydroxytryptamine | A metabolite of Melatonin. Group: Biochemicals. Alternative Names: N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]acetamide; 5-Hydroxy-N-acetyltryptamine; 5-Hydroxymelatonin; N-Acetylserotonin; Normelatonin. Grades: Highly Purified. CAS No. 1210-83-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| N-Acetyl-5-hydroxytryptamine | N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor. Uses: Scientific research. Group: Natural products. Alternative Names: N-Acetylserotonin; Normelatonin; O-Demethylmelatonin. CAS No. 1210-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-107854. | |
| Serotonin O-Sulfate (5-Hydroxytryptamine O-Sulfate) | Serotonin O-Sulfate (5-Hydroxytryptamine O-Sulfate). Group: Biochemicals. Alternative Names: 5-Hydroxytryptamine O-Sulfate. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 1-(1-Naphthyl)piperazine hydrochloride | 1-(1-Naphthyl)piperazine (1-NP) is a ligand for serotonin (5-hydroxytryptamine, 5-HT) receptors. It acts as an antagonist for 5-HT at 5-HT1 and 5-HT2 in rat cortical membranes with IC50 values of 6 and 1 nM, respectively. Synonyms: Piperazine, 1-(1-naphthalenyl)-, hydrochloride (1:1); Piperazine, 1-(1-naphthalenyl)-, monohydrochloride; 1-(Naphthalen-1-yl)piperazine hydrochloride; 1-NP hydrochloride; 1-(1-Naphthyl) piperazine monohydrochloride. Grades: ≥98%. CAS No. 104113-71-5. Molecular formula: C14H16N2.HCl. Mole weight: 248.75. | |
| 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one | 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one was used to prepare a congener of Trazadone which was found to be a potent and selective inhibitor of synaptosomal uptake of 5-hydroxytryptamine. Group: Biochemicals. Alternative Names: s-Triazolo[4,3-a]pyridin-3-ol; 3-Hydroxytriazolo[4,3-a]pyridine; NSC 68462. Grades: Highly Purified. CAS No. 6969-71-7. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| 1- (2-Chlorophenyl) piperazine Hydrochloride | 1- (2-Chlorophenyl) piperazine Hydrochloride is a reactant used in the preparation of piperazinyl, phenylpiperidinyl, tetrahydropyridinyl, and tetra hydropyridoindolyl butyl benzindoles with 5-hydroxytryptamine receptor antagonist activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 41202-32-8. Pack Sizes: 500mg, 1g. Molecular Formula: C10H14Cl2N2. US Biological Life Sciences. | Worldwide |
| 1-Phenylbiguanide | 1-Phenylbiguanide is a 5-hydroxytryptamine receptor agonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 102-02-3. Pack Sizes: 25g, 50g. Molecular Formula: C8H11N5, Molecular Weight: 177.21. US Biological Life Sciences. | Worldwide |
| 2,2'-(4,4'-(Oxybis(butane-4,1-diyl))bis(piperazine-4,1-diyl))dipyrimidine-D16 Dihydrochloride | 2,2'-(4,4'-(Oxybis(butane-4,1-diyl))bis(piperazine-4,1-diyl))dipyrimidine-D16 Dihydrochloride is deuterium labelled analogue of 2,2'-(4,4'-(Oxybis(butane-4,1-diyl))bis(piperazine-4,1-diyl))dipyrimidine Dihydrochloride (O868540), which is an impurity of anxiolytic drug Buspirone (B689855) that acts as 5-hydroxytryptamine (5-HT1) receptor agonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H22D16N8O; 2(HCl), Molecular Weight: 470.7123646. US Biological Life Sciences. | Worldwide |
| 2,2'-(4,4'-(Oxybis(butane-4,1-diyl))bis(piperazine-4,1-diyl))dipyrimidine Dihydrochloride | 2,2'-(4,4'-(Oxybis(butane-4,1-diyl))bis(piperazine-4,1-diyl))dipyrimidine is an impurity of anxiolytic drug Buspirone (B689855) that acts as 5-hydroxytryptamine (5-HT1) receptor agonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C24H38N8O; 2(HCl), Molecular Weight: 454.612364599999. US Biological Life Sciences. | Worldwide |
| 2,2'-[Butane-1,4-diylbis(piperazine-1,4-diyl)]dipyrimidine | 2,2'-[Butane-1,4-diylbis(piperazine-1,4-diyl)]dipyrimidine is compatible with some pharmaceutical excipients, also a derivative compound of Buspirone hydrochloride (B689850) which is a Non-benzodiazepine anxiolytic; 5-hydroxytryptamine (5-HT1) receptor agonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 257877-45-5. Pack Sizes: 25mg, 50mg. Molecular Formula: C20H30N8, Molecular Weight: 382.51. US Biological Life Sciences. | Worldwide |
| 2-(4-Benzyloxy-indol-3-yl)ethanamine Hemisulfate Salt | A tryptamine derivative, also an intermediate in the synthesis of the neurotransmitter agonist 4-Hydroxytryptamine Creatinine. Group: Biochemicals. Alternative Names: 2-(4-Benzyloxy-1H-indol-3-yl)ethylamine; 4-(Phenylmethoxy)-1H-indole-3-ethanamine Hemisulfate Salt. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 2-(4-Benzyloxy-indol-3-yl)-N,N,N-trimethylethanammonium Iodide | A tryptamine derivative, also an intermediate in the synthesis of the neurotransmitter agonist 4-Hydroxytryptamine Creatinine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| [2-(5-Benzyloxy-1H-indol-3-yl)ethyl]dimethylamine | [2-(5-Benzyloxy-1H-indol-3-yl)ethyl]dimethylamine has a potential ability to inhibit the oxidation of tryptamine and 5-hydroxytryptamine by suspensions of guinea-pig liver and rat fundus. Also, it is an intermediate used in the synthesis of Bufotenine Hydrochloride (B689465), which is a weak hallucinogenic agent active by intravenous injection. It is a constituent of toad poison. Group: Biochemicals. Grades: Highly Purified. CAS No. 25390-67-4. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H22N2O, Molecular Weight: 294.39. US Biological Life Sciences. | Worldwide |
| 2-Methyl-5-HT | 2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT 3 receptor agonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Methyl-5-hydroxytryptamine; 2-Methylserotonin; 2-Me-5-HT. CAS No. 78263-90-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19358. | |
| 2-Methylserotonin | 2-Methylserotonin. Group: Biochemicals. Alternative Names: 3-(2-Aminoethyl)-2-methylindole; 3-(2-Aminoethyl)-2-methyl-1H-indol-5-ol; 2-Me-5-HT; 2-Methyl-5-HT; 2-Methyl-5-hydroxytryptamine. Grades: Highly Purified. CAS No. 78263-90-8. Pack Sizes: 10mg. Molecular Formula: C11H14N2O, Molecular Weight: 190.24. US Biological Life Sciences. | Worldwide |
| 4-Benzyloxygramine | A A benzyloxyindole derivative, also an intermediate in the synthesis of the neurotransmitter agonist 4-Hydroxytryptamine Creatinine. Group: Biochemicals. Alternative Names: N,N-Dimethyl-4-(phenylmethoxy)-1H-indole-3-methanamine. Grades: Highly Purified. CAS No. 13523-95-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 4-Benzyloxyindole-3-acetonitrile | A tryptamine derivative, also an intermediate in the synthesis of the neurotransmitter agonist 4-Hydroxytryptamine Creatinine. Group: Biochemicals. Alternative Names: 4-Benzyloxy-3-indoleacetonitrile; 4-(Phenylmethoxy)-1H-indole-3-acetonitrile. Grades: Highly Purified. CAS No. 1464-11-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 5-Chloro Bifeprunox Mesylate | Used as an antipsychotic compound. Activates the serotonin 5-hydroxytryptamine (5-HT)1A receptor. Group: Biochemicals. Alternative Names: 7-[4-([1,1'-Biphenyl]-3-ylmethyl)-1-piperazinyl]-5-chloro-2(3H)-benzoxazolone Mesylate. Grades: Highly Purified. CAS No. 1217042-05-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 5-Hydroxytryptophan | 5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 5-HTP; DL-5-Hydroxytryptophan. CAS No. 56-69-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0122. | |
| Adenoregulin | Adenoregulin is an antimicrobial peptide produced by Phyllomedusa bicolor (Two-colored leaf frog, Rana bicolor). It has antibacterial and antifungal activity. It enhances binding of agonists to adenosine A1 receptors, adenosine A2a receptors, alpha-2 adrenergic receptors and 5-hydroxytryptamine 1A receptors. Synonyms: Dermaseptin BII; Dermaseptin B2; ADR; H-Gly-Leu-Trp-Ser-Lys-Ile-Lys-Glu-Val-Gly-Lys-Glu-Ala-Ala-Lys-Ala-Ala-Ala-Lys-Ala-Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala-Val-Ser-Glu-Ala-Val-OH; glycyl-L-leucyl-L-tryptophyl-L-seryl-L-lysyl-L-isoleucyl-L-lysyl-L-alpha-glutamyl-L-valyl-glycyl-L-lysyl-L-alpha-glutamyl-L-alanyl-L-alanyl-L-lysyl-L-alanyl-L-alanyl-L-alanyl-L-lysyl-L-alanyl-L-alanyl-glycyl-L-lysyl-L-alanyl-L-alanyl-L-leucyl-glycyl-L-alanyl-L-valyl-L-seryl-L-alpha-glutamyl-L-alanyl-L-valine. Grades: >85%. CAS No. 149260-68-4. Molecular formula: C142H242N40O42. Mole weight: 3181.73. | |
| Agomelatine | Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. Synonyms: AGO 178; AGO-178; AGO178; N-(2-(7-methoxy-1-naphthyl)ethyl)acetamide; S 20098; S-20098; S20098. trade names: Valdoxan, Melitor, Thymanax. Grades: 0.99. CAS No. 138112-76-2. Molecular formula: C15H17NO2. Mole weight: 243.31. | |
| Agomelatine-d6 | Agomelatine-d6 is labelled Agomelatine (A430000) which is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 1079389-42-6. Pack Sizes: 1mg. Molecular Formula: C15H11D6NO2, Molecular Weight: 249.34. US Biological Life Sciences. | Worldwide |
| Allura Red AC | Allura Red AC is a food colorant, appearing as a deep red water-soluble powder or granules, used in various applications such as beverages, syrups, candies, and cereals. Allura Red AC can statically quench the intrinsic fluorescence of HSA. Additionally, Allura Red AC is a 5-hydroxytryptamine ( 5-HT ) pathway-associated pro-inflammatory agent, capable of exacerbating experimental colitis. Allura Red AC holds potential for research in inflammatory bowel disease (IBD), intestinal barrier function, and food additive safety [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: FD&C RED NO. 40; CI 16035. CAS No. 25956-17-6. Pack Sizes: 50 mg; 100 mg. Product ID: HY-123630. | |
| Almotriptan Malate | Almotriptan Malate is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults. Uses: Serotonin receptor agonists. Synonyms: LAS 31416; LAS31416; LAS-31416. Grades: >98%. CAS No. 181183-52-8. Molecular formula: C17H25N3O2S.C4H6O5. Mole weight: 469.55. | |
| aralkylamine N-acetyltransferase | Narrow specificity towards 2-arylethylamines, including serotonin (5-hydroxytryptamine), tryptamine, 5-methoxytryptamine and phenylethylamine. This is the penultimate enzyme in the production of melatonin (5-methoxy-N-acetyltryptamine) and controls its synthesis (cf. EC 2.1.1.4, acetylserotonin O-methyltransferase). Differs from EC 2.3.1.5 arylamine N-acetyltransferase. Group: Enzymes. Synonyms: serotonin acetyltransferase; serotonin acetylase; arylalkylamine N-acetyltransferase; serotonin N-acetyltransferase; AANAT; melatonin rhythm enzyme. Enzyme Commission Number: EC 2.3.1.87. CAS No. 92941-56-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2268; aralkylamine N-acetyltransferase; EC 2.3.1.87; 92941-56-5; serotonin acetyltransferase; serotonin acetylase; arylalkylamine N-acetyltransferase; serotonin N-acetyltransferase; AANAT; melatonin rhythm enzyme. Cat No: EXWM-2268. |  |
| Bifeprunox Mesylate | Used as an antipsychotic compound. Activates the serotonin 5-hydroxytryptamine (5-HT)1A receptor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Buspirone Hydrochloride | Non-benzodiazepine anxiolytic; 5-hydroxytryptamine (5-HT1) receptor agonist. Group: Biochemicals. Alternative Names: 8-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione; Ansial; Ansiced. Grades: Highly Purified. CAS No. 33386-08-2. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C??H??ClN?O?, Molecular Weight: 421.96. US Biological Life Sciences. | Worldwide |
| Buspirone N-Oxide | Buspirone N-Oxide (Buspirone N Oxide Impurity) is a metabolite of Buspirone (B689850), a 5-hydroxytryptamine (5-HT1) receptor agonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 220747-81-9. Pack Sizes: 100mg, 1g. Molecular Formula: C21H31N5O3. US Biological Life Sciences. | Worldwide |
| Buspirone N-Oxide | Buspirone N-Oxide is a metabolite of Buspirone, a 5-hydroxytryptamine (5-HT1) receptor agonist. Synonyms: 8-[4-[1-Oxido-4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione. Grades: > 95%. CAS No. 220747-81-9. Molecular formula: C21H31N5O3. Mole weight: 401.51. | |
| Elzasonan | Elzasonan is a selective 5-hydroxytryptamine 1B receptor antagonist that was developed by Pfizer (and then later discontinued in 2008) to treat patients with major depressive disorder and obsessive compulsive disorder. Group: Biochemicals. Grades: Highly Purified. CAS No. 361343-19-3. Pack Sizes: 50mg, 500mg. Molecular Formula: C22H23Cl2N3OS, Molecular Weight: 448.41. US Biological Life Sciences. | Worldwide |
| Elzasonan citrate | Elzasonan citrate is a selective 5-hydroxytryptamine 1B receptor antagonist for treat patients with major depressive disorder and obsessive compulsive disorder. Uses: Serotonin 1b receptor antagonists; serotonin 1d receptor antagonists. Synonyms: (2Z)-4-(3,4-dichlorophenyl)-2-[[2-(4-methylpiperazin-1-yl)phenyl]methylidene]thiomorpholin-3-one;2-hydroxypropane-1,2,3-tricarboxylic acid. Grades: ≥98%. CAS No. 361343-20-6. Molecular formula: C28H31Cl2N3O8S. Mole weight: 640.53. | |
| Flesinoxan | Flesinoxan is a hypotensive agent and a potent, high affinity and selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist with an EC 50 value of 24 nM. Flesinoxan also has effective anxiolytic/antidepressant effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 98206-10-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-121653. | |
| GSK215083 | GSK215083 is a PET radioligand for the 5-hydroxytrypamine-6 (5HT6) receptor. It is a quinoline based compounds that acts by antagonising the 5-HT6 receptor. It binds to receptors 5HT6 in the striatum and 5-hydroxytryptamine-2A (5HT2A) in the frontal cortex. It is used for the treatment of Alzheimer's disease and used as a PET ligand for identification of occupancy of the 5HT6 receptor coupled with 11C. Uses: Gsk215083 is used for the treatment of alzheimer's disease and used as a pet ligand for identification of occupancy of the 5ht6 receptor coupled with 11c. Synonyms: GSK-215083; GSK 215083; GSK215083; 3-(3-Fluoro-benzenesulfonyl)-8-(4-Methyl-piperazin-1-yl)-quinoline;GSK-215083;Quinoline, 3-((3-fluorophenyl)sulfonyl)-8-(4-methyl-1-piperazinyl)-. Grades: 98%. CAS No. 607742-80-3. Molecular formula: C20H20FN3O2S. Mole weight: 385.46. | |
| Indatraline hydrochloride | Indatraline hydrochloride is the hydrobromide salt of indatraline, which is a potent monoamine uptake inhibitor. It inhibits the synaptosomal uptake of noradrenaline, 3,4-dihydroxyphenylethylamine and 5-hydroxytryptamine with Ki values of 5.8, 1.7 and 0.42 nM respectively. It is centrally active following systemic administration in vivo. Synonyms: 1H-Inden-1-amine, 3-(3,4-dichlorophenyl)-2,3-dihydro-N-methyl-, hydrochloride (1:1), (1R,3S)-rel-; 1H-Inden-1-amine, 3-(3,4-dichlorophenyl)-2,3-dihydro-N-methyl-, monohydrochloride, (1R,3S)-rel-; 1H-Inden-1-amine, 3-(3,4-dichlorophenyl)-2,3-dihydro-N-methyl-, hydrochloride, trans-(±)-; 1H-Inden-1-amine, 3-(3,4-dichlorophenyl)-2,3-dihydro-N-methyl-, hydrochloride, trans-; Indatraline monohydrochloride; Lu 19-005. Grades: ≥99% by HPLC. CAS No. 96850-13-4. Molecular formula: C16H16Cl3N. Mole weight: 328.67. | |
| Indole-5-carboxylic acid, 98% | Indole-5-carboxylic acid, 98% is an oxytocin that interacts with serotonin receptors and gamma-aminobutyric acid (GABA) receptors. It has also been reported to interact with various enzymes such as cyclooxygenase-2 (COX-2) and 5-hydroxytryptamine (5-HT) receptors. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1670-81-1. Pack Sizes: 5 g. Product ID: HY-59302. | |
| JNJ-18038683 | JNJ-18038683 is a 5-Hydroxytryptamine Type 7 ( 5-HT 7 ) receptor antagonist, with pK i s of 8.19, 8.20 for rat and human 5-HT 7 in HEK293 cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 851376-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19889. | |
| Lofepramine | Lofepramine (Lopramine) is a modified tricyclic and orally active antidepressant. Lofepramine inhibits the uptake of Noradrenaline (NA) (HY-13715) and 5-hydroxytryptamine (5-HT) with IC 50 s of 2.7 μM and 11 μM, respectively. Lofepramine exerts its antidepressant activity by promoting noradrenergic neurotransmission. Lofepramine also enhances serotonergic neurotransmission by inhibiting neuronal uptake of 5-HT and tryptophan pyrrolase. Lofepramine exhibits significant anxiolytic properties. [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lopramine. CAS No. 23047-25-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12390. | |
| ML 10302 | ML 10302 is a potent agonist 5-HT4 receptor with K i of 1.07 nM. 5-Hydroxytryptamine (5-HT4) receptor agonists stimulate gut motility through cholinergic pathways. ML10302 induces significant prokinesia both in the small bowel and colon through activation of cholinergic pathways. ML 10302 also has the potential for the research of neurology diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 148868-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14441. | |
| N-Methyl Serotonin | N-Methylserotonin is the N-methylated derivative of serotonin with similar activity. Studies have identified N-Methylserotonin as a potential active constituent that contributes to the serotonergic activity of black cohosh. Group: Biochemicals. Alternative Names: 3-[2-(Methylamino)ethyl]-1H-indol-5-ol; 3-[2- (Methylamino) ethyl]indol-5-ol; 5-Hydroxy-N-methyltryptamine; 5-Hydroxy-Nω-methyltryptamine; N-Methyl-5-hydroxytryptamine; N-Methylserotonin. Grades: Highly Purified. CAS No. 1134-01-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| N,O-Diacetyl Serotonin | An impurity of serotonin. Serotonin is a monoamine neurotransmitter and popularly thought to be a contributor to feelings of well-being and happiness. Synonyms: Acetamide, N-[2-[5-(acetyloxy)?-1H-indol-3-yl]?ethyl]?-; Acetamide, N-[2-(5-hydroxyindol-3-yl)ethyl]-, acetate (7CI);Acetamide, N-[2-(5-hydroxyindol-3-yl)ethyl]-, acetate (ester) (8CI);N-[2-[5-(Acetyloxy)-1H-indol-3-yl]ethyl]acetamide;Diacetyl-5-hydroxytryptamine;N-Acetyl-2-(5-acetoxyindol-3-yl)ethylamine. Grades: > 95%. CAS No. 28026-16-6. Molecular formula: C14H16N2O3. Mole weight: 260.29. | |
| PRX 08066 | PRX 08066, a selective 5-hydroxytryptamine receptor 2B(5-HT2BR) antagonist, causes selective vasodilation of pulmonary arteries. Its IC50 value is 3.4 nM. It can potentially inhibit the pathologic 5-HT-induced vascular muscularization and is developed to treat for pulmonary arterial hypertension (PAH). It reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. It shows effects on the vascular muscularization induced by 5-HT in the in vitro studies. It inhibits 5-HT-induced mitogen-activated protein kinase activation and markedly reduces thymidine incorporation in Chinese hamster ovary cells expressing the human 5-HT2BR in vitro. It decrea...ts and mice without affecting the systemic mean arterial pressure in the animals. It is also found to have anti-proliferative and anti-fibrotic effects. It was developed by Allergan company and is in clinical phase 2 with no progression. Uses: Prx 08066 can potentially inhibit the pathologic 5-ht-induced vascular muscularization and is developed to treat for pulmonary arterial hypertension (pah). it is also found to have anti-proliferative and anti-fibrotic effects. Synonyms: PRX-08066; PRX 08066; PRX08066. 5-[[4-[(6-chlorothieno[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]methyl]-2-fluorobenzonitrile. Grades: >98%. CAS No. 866206-54-4. Molecular formula: C19H17ClFN5S. Mole weight: 401.89. | |
| PRX-08066 | PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3. Uses: Scientific research. Group: Signaling pathways. CAS No. 866206-54-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15472. | |
| RuBi-5-HT | RuBi-5-HT, a highly water-soluble caged-serotonin (5-HT) compound based on ruthenium photochemistry, is a monoamine neurotransmitter and has no effect on firing of pyramidal neurons in mice; uncaging with blue light alters firing rate of COM and CPn neurons, which is blocked by MDL 100907. Synonyms: (bis(2,2'-Bipyridine-N,N')trimethylphosphine)-5-hydroxytryptamine ruthenium(2+) dihexafluorophosphate complex. Molecular formula: C33H37F12N6OP3Ru. Mole weight: 955.66. | |
| Sapropterin Dihydrochloride | Tetrahydrobiopterin (BH4, THB), also known as sapropterin, is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin (5-hydroxytryptamine, 5-HT), melatonin, dopamine, norepinephrine (noradrenaline), epinephrine (adrenaline), and is a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases.[1] Chemically, its structure is that of a reduced pteridine derivative. Group: Biochemicals. Alternative Names: (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride; 6R-BH4. CAS No. 17528-72-2. Pack Sizes: 50mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| SB 271046 Hydrochloride | SB 271046 Hydrochloride is the hydrochloride salt form of SB 271046. SB 271046 is an orally-available and selective antagonist of the serotonin (5-hydroxytryptamine or 5-HT) receptor 5-HT6 with at least 100-fold selective for 5-HT6 (pKi = 9.02-8.92) over. Synonyms: 5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methyl-benzo[b]thiophene-2-sulfonamide Hydrochloride; SB 271046A. CAS No. 209481-24-3. Molecular formula: C20H23Cl2N3O3S2. Mole weight: 488.45. | |
| Serotonin | Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase ( COMT ) inhibitor with a K i of 44 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 5-Hydroxytryptamine; 5-HT. CAS No. 50-67-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1473A. | |
| Serotonin Glucuronide | A metabolite of serotonin. Serotonin is a monoamine neurotransmitter and popularly thought to be a contributor to feelings of well-being and happiness. Synonyms: 3-(2-Aminoethyl)-1H-indol-5-yl β-D-Glucopyranosiduronic acid; 5-Hydroxytryptamine O-Glucuronide; 5-Hydroxytryptamine Glucuronide; Serotonin β-D-Glucuronide. Grades: > 95%. CAS No. 18186-43-1. Molecular formula: C16H20N2O7. Mole weight: 352.35. | |
| Serotonin hydrochloride | Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase ( COMT ) inhibitor with a K i of 44 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 5-Hydroxytryptamine hydrochloride; 5-HT hydrochloride. CAS No. 153-98-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-B1473. | |
| Serotonin Hydrochloride | Serotonin is a monoamine neurotransmitter. Group: Biochemicals. Alternative Names: 3-(2-Aminoethyl)-1H-indol-5-ol Hydrochloride; 5-Hydroxytryptamine Hydrochloride; Hippophaine Hydrochloride. Grades: Highly Purified. CAS No. 153-98-0. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| Serotonin O-Ethyl-methanethiosulfonate Hydrochloride | An methantiosulfonate (MTS) derivative of the neurotransmitter Serotonin. Group: Biochemicals. Alternative Names: 5-Hydroxytryptamine O-Ethyl-methanethiosulfonate Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Vabicaserin hydrochloride | Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C ( 5-HT 2C ) receptor -selective agonist with an EC 50 of 8 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCA 136. CAS No. 887258-94-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111200. | |
| Vortioxetine hydrobromide | Vortioxetine (Lu AA 21004) hydrobromide is an antagonist of 5-HT 3A and 5-HT 7 receptors (K i : 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (K i : 1.6 nM), as well as a 5-HT 1A agonist and a partial 5-HT 1B agonist (K i : 15 nM, 33 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu AA21004 hydrobromide. CAS No. 960203-27-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15414A. | |
| WAY-100635 | WAY-100635 is a potent and selective 5-HT 1A Receptor antagonist with a pIC 50 of 8.87, an apparent pA 2 of 9.71. WAY-100635 is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC 50 value of 0.91 nM and K i value of 0.39 nM. WAY-100635 has pIC 50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 is also a potent dopamine D 4 receptor agonist [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 162760-96-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10349. | |
| WAY-100635 maleate | WAY-100635 maleate is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC 50 value of 0.91 nM and K i value of 0.39 nM. WAY-100635 maleate has pIC 50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 maleate is also a potent dopamine D 4 receptor agonist [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092679-51-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10349A. | |
| WAY-100635 maleate | WAY-100635 maleate is a potent and selective 5-hydroxytryptamine1A antagonist for 5-HT ( IC50= 0.95 ± 0.12 nM ), and also exhibits agonist activity at dopamine D4 receptors. Uses: Potent, silent antagonist of 5-ht1a receptors. Synonyms: WAY-100635 maleate; WAY 100635 maleate; WAY100635 maleate; (Z)-but-2-enedioic acid;N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylcyclohexanecarboxamide. Grades: ≥98%. CAS No. 634908-75-1. Molecular formula: C29H38N4O6. Mole weight: 538.64. | |
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