Ibrutinib Suppliers USA
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Product | Description | |
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Ibrutinib Quick inquiry Where to buy Suppliers range | Ibrutinib is a potent and selective BTK inhibitor (IC50=0.5 nM). Synonyms: PCI-32765; PCI 32765; (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: ≥95%. CAS No. 936563-96-1. Molecular formula: C25H24N6O2. Mole weight: 440.50. | |
Ibrutinib Quick inquiry Where to buy Suppliers range | Ibrutinib Inhibitor. Uses: Scientific use. Product Category: T1835. CAS No. 936563-96-1. | |
Ibrutinib, 98% Quick inquiry Where to buy Suppliers range | Ibrutinib, 98%. Group: Cancer Research. CAS No. 936563-96-1. Pack Sizes: 5mg. ID EBT829. | |
Ibrutinib-d4 Quick inquiry Where to buy Suppliers range | Ibrutinib-d4 is the labelled analogue of Ibrutinib (I124970). Ibrutinib is a highly selective BrutonÂs tyrosine kinase (Btk) irreversible inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H20D4N6O2, Molecular Weight: 444.52. US Biological Life Sciences. | Worldwide |
Ibrutinib-d4 (Major) Quick inquiry Where to buy Suppliers range | Ibrutinib-d4 (Major). Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS001951. Format: Neat. | |
Ibrutinib Dimer Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib impurity MDAEJ; 2-Propen-1-one, 1-[(3R)-3-[4-[[3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-oxopropyl]amino]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-; 1-((R)-3-(4-((3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: ≥95%. CAS No. 2031255-23-7. Molecular formula: C50H48N12O4. Mole weight: 880.99. | |
Ibrutinib Dimer (~90%) Quick inquiry Where to buy Suppliers range | Ibrutinib Dimer (~90%). Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates; Impurity Standards. Catalog: APS001950. Format: Neat. Product Type: Impurity. | |
Ibrutinib, Free Base Quick inquiry Where to buy Suppliers range | Ibrutinib, also known as PCI-32765, is a selective and irreversible inhibitor of the enzyme Bruton's tyrosine kinase (BTK). It inhibited BTK potently, with an IC50 of 0.72 nM in enzymology assays and with an IC50 of 10 nM in cellular assay with Ramos cells. It demonstrated preference toward BTK over closely related kinases, blocked B cell function and BTK-dependent processes, and demonstrated clear efficacy in a mouse arthritis model. Young P.R., et al. "Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase." ChemMedChem. 2: 58-61 (2007). Group: Biochemicals. Alternative Names: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one; PCI 32765; PCI 32765-00; CRA 032765; (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one; Imbruvica. Grades: Purified. CAS No. 936563-96-1. Pack Sizes: 5mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
Ibrutinib Impurity 1 Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 1-Piperidinecarboxylic acid, 3-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-, 1,1-diMethylethyl ester, (3R)-; (R)-tert-Butyl 3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate. Grades: > 95%. CAS No. 1022150-11-3. Molecular formula: C27H30N6O3. Mole weight: 486.58. | |
Ibrutinib Impurity 2 Quick inquiry Where to buy Suppliers range | Grades: > 95%. Molecular formula: C28H26N6O3. Mole weight: 494.56. | |
Ibrutinib Impurity 3 Quick inquiry Where to buy Suppliers range | Synonyms: PCI-45227. Grades: > 95%. CAS No. 1226872-27-0. Molecular formula: C25H26N6O4. Mole weight: 474.52. | |
Ibrutinib Impurity 4 Quick inquiry Where to buy Suppliers range | Grades: > 95%. Molecular formula: C25H24N6O3. Mole weight: 456.51. | |
Ibrutinib Impurity 5 Quick inquiry Where to buy Suppliers range | Ibrutinib Impurity 5 is an impurity in commercial preparation of Ibrutinib. Synonyms: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one. Grades: > 95%. Molecular formula: C25H25ClN6O2. Mole weight: 476.97. | |
Ibrutinib Impurity 6 Quick inquiry Where to buy Suppliers range | Synonyms: Ibrutinib impurity 6; 1987905-93-0; ZPJ4HT8UNA; UNII-ZPJ4HT8UNA; 1,3-Bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one (Imatinib Impurity); 1-Propanone, 1,3-bis((3R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-; 1,3-bis[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one; 3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-1-[(3R)-3-[4-imino-3-(4-phenoxyphenyl)-1H,2H,4H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one; 1,3-bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidin-1-yl)propan-1-one;1,3-Bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one; 1,3-Bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one? (Imatinib Impurity; Ibrutinib Addition Adduct with (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl). Grades: > 95%. Molecular formula: C47H46N12O3. Mole weight: 826.97. | |
Ibrutinib Impurity 8 Quick inquiry Where to buy Suppliers range | Ibrutinib Impurity 8 is a useful synthetic intermediate in the synthesis of Ibrutinib, a highly selective Bruton's tyrosine kinase (BTK) irreversible inhibitor. Synonyms: 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine; 4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-; Ibrutinib intermeidate N-2. Grades: ≥97% by HPLC. CAS No. 330786-24-8. Molecular formula: C17H13N5O. Mole weight: 303.33. | |
Ibrutinib Impurity HNEJ Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C49H46N12O4. Mole weight: 866.99. | |
Ibrutinib Impurity IMYBJ Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C20H19N5O. Mole weight: 345.41. | |
Ibrutinib Impurity JXBJ Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C26H26N6O2. Mole weight: 454.53. | |
Ibrutinib Impurity MDDYH Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. CAS No. 2052279-49-7. Molecular formula: C25H24N6O3. Mole weight: 456.51. | |
Ibrutinib Impurity SMSJ Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C32H24N8O2. Mole weight: 552.60. | |
Ibrutinib Methoxy Impurity Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-methoxypropan-1-one; Ibrutinib impurity JYD. Grades: ≥95%. CAS No. 2031255-26-0. Molecular formula: C26H28N6O3. Mole weight: 472.55. | |
Dihydrodiol Ibrutinib Quick inquiry Where to buy Suppliers range | Dihydrodiol Ibrutinib. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS001536. Format: Neat. | |
N1,N6 [ 1,3-(1-Oxopropylene)] Ibrutinib Quick inquiry Where to buy Suppliers range | N1,N6 [ 1,3-(1-Oxopropylene)] Ibrutinib is an impurity of Ibrutinib (I124970), a highly selective BrutonÂs tyrosine kinase (Btk) irreversible inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C28H26N6O3, Molecular Weight: 494.54. US Biological Life Sciences. | Worldwide |
(R)-N-Desacryloyl N-3-Propionyl Ibrutinib Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one. Grades: ≥95%. CAS No. 1288338-96-4. Molecular formula: C25H25ClN6O2. Mole weight: 476.96. | |
(R)-N-Desacryloyl N-Propionyl Ibrutinib Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 1-Propanone, 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-. Grades: ≥95%. CAS No. 1839099-22-7. Molecular formula: C25H26N6O2. Mole weight: 442.51. | |
(S)-Ibrutinib Quick inquiry Where to buy Suppliers range | (S)-Ibrutinib. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Pack Sizes: 5MG. Catalog: APS003785. Format: Neat. Shipping: Dry ice. | |
(S)-Ibrutinib Quick inquiry Where to buy Suppliers range | (S)-Ibrutinib is a highly selective Bruton's tyrosine kinase (Btk) irreversible inhibitor. Synonyms: 1-[(3S)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one; (S)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: > 95%. CAS No. 936563-97-2. Molecular formula: C25H24N6O2. Mole weight: 440.51. | |
(S)-Ibrutinib Quick inquiry Where to buy Suppliers range | (S)-Ibrutinib. Group: Biochemicals. Alternative Names: 1-[(3S)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one; (S)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: Highly Purified. CAS No. 936563-97-2. Pack Sizes: 5mg. Molecular Formula: C25H24N6O2, Molecular Weight: 440.5. US Biological Life Sciences. | Worldwide |
(S)-Ibrutinib-d5 Quick inquiry Where to buy Suppliers range | (S)-Ibrutinib-d5. Group: Biochemicals. Alternative Names: 1-[(3S)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one-d5; (S)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one-d5. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H19D5N6O2, Molecular Weight: 445.53. US Biological Life Sciences. | Worldwide |
1,3-bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidin-1-yl)propan-1-one Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 1-Propanone, 1,3-bis((3R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-; Ibrutinib impurity PDEJ. Grades: ≥95%. CAS No. 1987905-93-0. Molecular formula: C47H46N12O3. Mole weight: 826.97. | |
1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one Quick inquiry Where to buy Suppliers range | 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one. Group: Biochemicals. Alternative Names: Ibrutinib; PCI-32765. Grades: Highly Purified. CAS No. 936563-96-1. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C25H24O2N6. US Biological Life Sciences. | Worldwide |
1-[4-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 2-Propen-1-one, 1-[4-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-1-piperidinyl]-; Ibrutinib Impurity WZYG. Grades: ≥95%. CAS No. 936563-92-7. Molecular formula: C25H24N6O2. Mole weight: 440.50. | |
1-butyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib Impurity IMDJ. Grades: ≥95%. CAS No. 2213398-77-5. Molecular formula: C21H21N5O. Mole weight: 359.43. | |
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-ethyl-3-(4-phenoxyphenyl)- Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib Impurity IMYJ. Grades: ≥95%. CAS No. 2213398-76-4. Molecular formula: C19H17N5O. Mole weight: 331.37. | |
1-Methyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-methyl-3-(4-phenoxyphenyl)-; Ibrutinib impurity JBZ. Grades: ≥95%. CAS No. 2213398-75-3. Molecular formula: C18H15N5O. Mole weight: 317.34. | |
BGB-3111 Quick inquiry Where to buy Suppliers range | BGB-3111 is a potent, selective and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability, achieving higher exposure and more complete target inhibition in the tissues than ibrutinib. Uses: Antineoplastic agents. Synonyms: 2-(4-phenoxyphenyl)-7-(1-prop-2-enoylpiperidin-4-yl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide; SCHEMBL16208602; BDBM249900; BGB-3111; BGB 3111; BGB3111. CAS No. 1633350-06-7. Molecular formula: C27H29N5O3. Mole weight: 471.55. | |
PCI-32765 Racemate Quick inquiry Where to buy Suppliers range | PCI-32765 Racemate is a potent and highly selective inhibitor of Bruton tyrosine kinase (BTK), modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc. It is a covalent and irreversible inhibitor of BTK through bonding to Cys-481 in the ATP binding domain. It inhibits phosphorylation of BTK in a B cells as well as the downstream substrates phosphoinositide phospholipase Cγ (PLC γ) and ERK in cell assays. It has in vivo efficacy in B cell lymphoma and efficacious in autoimmune disease. It also diminished FcγRIII-induced production of pro-inflammatory cytokines. Synonyms: Ibrutinib Racemate; PCI-32765 Racemate; PCI 32765 Racemate; PCI32765 Racemate. Grades: >98%. CAS No. 936563-87-0. Molecular formula: C25H24N6O2. Mole weight: 440.5. | |
(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethanone Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib impurity YX. Grades: ≥95%. CAS No. 1288338-95-3. Molecular formula: C24H24N6O2. Mole weight: 428.49. | |
(R)-1-((R)-1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine 1-oxide Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib Impurity BZDYH. Grades: ≥95%. CAS No. 2031255-25-9. Molecular formula: C25H24N6O3. Mole weight: 456.51. | |
(R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl acrylate Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 2-Propenoic acid, 3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-oxopropyl ester; Ibrutinib Impurity BXSJC. Grades: ≥95%. CAS No. 2244619-11-0. Molecular formula: C28H28N6O4. Mole weight: 512.56. | |
(R)-8-(1-acryloylpiperidin-3-yl)-10-(4-phenoxyphenyl)-3,4-dihydropyrazolo[4,3-e]pyrimido[1,2-c]pyrimidin-2(8H)-one Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib Impurity MDGH. Grades: ≥95%. CAS No. 1917333-91-5. Molecular formula: C28H26N6O3. Mole weight: 494.54. | |
(S)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Quick inquiry Where to buy Suppliers range | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib impurity SYGIM. Grades: ≥95%. CAS No. 1642630-12-3. Molecular formula: C22H22N6O. Mole weight: 386.45. | |
Zilovertamab Quick inquiry Where to buy Suppliers range | Zilovertamab is a first-in-class humanized monoclonal antibody that binds to ROR1. Zilovertamab has been undergoing clinical trials in combination with ibrutinib for the treatment of mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL). Synonyms: cirmtuzumab; UC-961. CAS No. 2485779-13-1. |