Inositol Kinase Suppliers USA
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Product | Description | |
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BAMB-4 Quick inquiry Where to buy Suppliers range | BAMB-4 is a new membrane-permeable inhibitor against inositol-1,4,5-trisphosphate-3-kinase A((ITPKA). It exhibits the lowest inhibition frequency among the InsP3-Kinase inhibitors. It is a promising therapeutic approach in lung cancer therapy. Synonyms: Bamb-4; Bamb 4; Bamb4; ITPKA-IN-C14. Grades: >98%. CAS No. 891025-25-5. Molecular formula: C15H12N2O2. Mole weight: 252.27. | |
bpV(phen) potassium hydrate Quick inquiry Where to buy Suppliers range | BpV(phen) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs) with IC50 of 38 nM. It also inhibits the vascular endothelial PTP-β with IC50 of 343 nM and PTP-1β with IC50 of 920 nM. At 0.1 mM, bpV(phen) inhibits SH2 domain-containing inositol 5'-phosphatase-2. Presumably by inhibiting insulin receptor kinase-associated PTPs, bpV(phen) activates the insulin receptor tyrosine kinase and promotes downstream signaling, including activation of PI3-kinase. Synonyms: Bisperoxovanadium(phen); Potassium Bisperoxo(1,10-phenanthroline) oxovanadate (V). Grades: ≥98%. CAS No. 171202-16-7. Molecular formula: C12H8N2O5V·K+(H2O)3. Mole weight: 404.3. | |
D-myo-Inositol-1,3,4,5,6-pentaphosphate ammonium salt Quick inquiry Where to buy Suppliers range | Inositol-1,3,4,5,6-pentaphosphateis one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-kinase/1-phosphatase cycle, as well as with Ins(1,4,5,6)P4 in a 3-kinase/3-phosphatase cycle. Grades: >98%. Molecular formula: C6H7O21P5·10NH4. Mole weight: 750.36. | |
D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium salt Quick inquiry Where to buy Suppliers range | The phosphatidylinositol 3-kinase (PI3K)/Akt signal transduction pathway plays critical roles in cell growth and proliferation making it an attractive target for anticancer agents. Inositol-1,3,4,5,6-pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It exhibits antiangiogenic activity in vitro, blocking capillary tube formation of HUVEC, as well as antitumor effects against cancer xenografts in nude mice. Grades: ≥98%. Molecular formula: C6H12O21P5·5Na. Mole weight: 689.96. | |
D-myo-Inositol-1,3,4,5-tetraphosphate sodium salt Quick inquiry Where to buy Suppliers range | D-myo-Inositol-1,3,4,5-tetraphosphate sodium salt is formed by the phosphorylation of Ins(1,4,5)P4 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)P4 acts in conjunction with IP3 to mobilize intracellular calcium. Synonyms: D-myo-Inositol-1,3,4,5-tetrakis(phosphate) octasodium salt; Ins(1,3,4,5)P4 sodium salt. CAS No. 210488-61-2. Molecular formula: C6H8Na8O18P4. Mole weight: 675.93. | |
D-myo-Inositol-1,3,4-triphosphate sodium salt Quick inquiry Where to buy Suppliers range | D-myo-Inositol-1,3,4-triphosphate (Ins(1,3,4)-P3) is one of several different inositol oligophosphate isomers implicated in signal transduction. Ins(1,3,4)-P3 acts through the inhibition of Ins(3,4,5,6)-P4 kinase activity to increase the cellular level of Ins(3,4,5,6)-P4 and thus inhibit calcium-activated chloride channels. Synonyms: D-myo-Inositol-1,3,5-triphosphate, sodium salt; 1,3,4-IP3 (sodium salt); 1,3,5-IP3 (sodium salt); HMS3650K09; Ins(1,3,5)P3 (sodium salt); Ins(1,3,4)-P3 (sodium salt); PD020265; D-myo-Inositol-1,3,4-triphosphate sodium salt. Grades: ≥98%. Molecular formula: C6H12Na3O15P3. Mole weight: 486.04. | |
IP3(1,3,4) ammonium salt Quick inquiry Where to buy Suppliers range | IP3(1,3,4) ammonium salt is a chemical which occurs naturally in carbachol-stimulated rat parotid glands. Ins(1,3,4)P3 inhibits Ins(3,4,5,6)P4 1-kinase which regulates Ins(3,4,5,6)P4 levels. Synonyms: D-Myo-inositol-1,3,4-triphosphate (ammonium salt); rac-(1R,2R,3R,4R,5S,6S)-3,5,6-Trihydroxycyclohexane-1,2,4-triyl tris(dihydrogen phosphate), Triammonia Salt. Grades: >97%. CAS No. 1246355-66-7. Molecular formula: C6H24N3O15P3. Mole weight: 471.19. | |
L-a-lysophosphatidyl inositol Sodium Salt, Soy (L-a-lysophosphatidyl inositol LPI, Lyso PI, Soy Lyso PI) Quick inquiry Where to buy Suppliers range | A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1uM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55. Group: Biochemicals. Grades: Highly Purified. CAS No. 796963-91-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
m-3M3FBS Quick inquiry Where to buy Suppliers range | m-3M3FBS is a direct activator of phospholipase C (PLC) that stimulates the increase in cytoplasmic calcium, inositol phosphate formation and superoxide generation in a variety of cell types. It is used in biological studies on Ca2+ homeostasis independently of phospholipase C activation. It is also used to study PLC signaling in cells and animals, often in conjunction with the PLC inhibitor U-73122. It has also been used for intracellular calcium analysis and MAP kinase assay in 293T cells. It also inhibits growth of the leukemic cell lines U937 and THP-1. Synonyms: m-3M3FBS; m 3M3FBS; m3M3FBS; 2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]-benzenesulfonamide; N-(3-Trifluoromethylphenyl)-2,4,6-trimethylbenzenesulfonamide. Grades: ≥99% by HPLC. CAS No. 200933-14-8. Molecular formula: C16H16F3NO2S. Mole weight: 343.36. | |
Phytic Acid, 50% Aqueous Solution Quick inquiry Where to buy Suppliers range | The principal storage form of phosphorus in many plant tissues, especially bran and seeds. It has antioxidant effect as well as neuroprotective effect by chelating iron. Inositol hexakisphosphate kinase type 2 (InsP6K2), which converts phytic acid to inositol pyrophosphate diphosphoinositol pentakisphosphate, is believed to induce pathogenesis of Huntington disease (HD). Group: Biochemicals. Alternative Names: myo-Inositol 1,2,3,4,5,6-Hexakis(dihydrogen phosphate); Alkalovert; Dermofeel PA 3; Exfoderm; Exfoderm Forte; Fytic Acid; IP6; Inositol 1,2,3,4,5,6-Hexakisphosphate; Inositol Hexakis(phosphate); Inositol hexaphosphate; InsP6; Phyliance; RP 3000; WHL; meso-Inositol hexaphosphate; myo-Inositol hexakis(phosphate); myo-Inositol hexaphosphate. Grades: Highly Purified. CAS No. 83-86-3. Pack Sizes: 25ml, 100ml, 250ml. Molecular Formula: C?H??O??P?, Molecular Weight: 660.04. US Biological Life Sciences. | Worldwide |
Phytic Acid Hexatriethylammonium Salt Quick inquiry Where to buy Suppliers range | The principal storage form of phosphorus in many plant tissues, especially bran and seeds. It has antioxidant effect as well as neuroprotective effect by chelating iron. Inositol hexakisphosphate kinase type 2 (InsP6K2), which converts phytic acid to inositol pyrophosphate diphosphoinositol pentakisphosphate, is believed to induce pathogenesis of Huntington disease (HD). Group: Biochemicals. Alternative Names: myo-Inositol 1,2,3,4,5,6-Hexakis(dihydrogen phosphate) Hexatriethylammonium Salt; Alkalovert Hexatriethylammonium Salt; Dermofeel PA 3 Hexatriethylammonium Salt; Exfoderm Hexatriethylammonium Salt; Exfoderm Forte Hexatriethylammonium Salt; Fytic Acid Hexatriethylammonium Salt; IP6; Inositol 1,2,3,4,5,6-Hexakisphosphate Hexatriethylammonium Salt; Inositol Hexakis(phosphate) Hexatriethylammonium Salt; Inositol hexaphosphate Hexatriethylammonium Salt; InsP6; Phyliance Hexatriethylammonium Salt; RP 3000 Hexatriethylammonium Salt; WHL Hexatriethylammonium Salt; meso-Inositol hexaphosphate Hexatriethylammonium Salt; myo-Inositol hexakis(phosphate) Hexatriethylammonium Salt; myo-Inositol hexaphosphate Hexatriethylammonium Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
SH-5 Quick inquiry Where to buy Suppliers range | SH-5 is a potent and selective Src kinase inhibitor widely used in biomedical research on multiple diseases, including cancer, osteoporosis and cardiovascular disorders. Synonyms: SH-5, SH 5; SH5; PIA-5; PIA5; PIA 5; L-chiro-Inositol, 1-deoxy-6-O-methyl-, 5-[(2R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate]. Akt inhibitor II. Grades: 98%. CAS No. 701976-54-7. Molecular formula: C29H59O10P. Mole weight: 598.75. | |
SH-5 (D-3-Deoxy-2-O-methyl-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate) Quick inquiry Where to buy Suppliers range | A cell-permeable inhibitor of Akt activation without affecting the activation of the upstream kinase PDK1 or other kinases downstream of Ras such as MAPK. Induces apoptosis and kills a variety of cancer cell lines containing high levels of active Akt. Group: Biochemicals. Alternative Names: D-3-Deoxy-2-O-methyl-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
SH-6 (D-2,3-Dideoxy-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate) Quick inquiry Where to buy Suppliers range | A cell-permeable inhibitor of Akt activation without affecting the activation of the upstream kinase PDK1 or other kinases downstream of Ras such as MAPK. Induces apoptosis and kills a variety of cancer cell lines containing high levels of active Akt. Group: Biochemicals. Alternative Names: D-2,3-Dideoxy-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
TNP Quick inquiry Where to buy Suppliers range | TNP is a reversible and cell-permeable inhibitor of inositol hexakisphosphate kinase (IP6K) (IC50 = 0.47 μM for inhibition of InsP7 formation) and inositol 1,4,5-trisphosphate 3-kinase (IP3K) (IC50 = 10.2 μM). Synonyms: N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine; IP3K Inhibitor; Inositol-1,4,5-trisphosphate 3-Kinase Inhibitor. Grades: ≥97% by HPLC. CAS No. 519178-28-0. Molecular formula: C20H16F3N7O2. Mole weight: 443.38. | |
TNP (N6-[ (4-nitrophenyl) methyl]-N2-[[3- (trifluoromethyl) phenyl]methyl]-9H-Purine-2, 6-diami ne) Quick inquiry Where to buy Suppliers range | Reversible inositol hexakisphosphate kinase (IP6K) inhibitor (IC50 = 0.47um for inhibition of InsP7 formation). Also inhibits inositol 1,4,5-trisphosphate 3-kinase (IP3K) (IC50 = 10.2um). Binds to the ATP binding site of IP3K (Ki = 4.3um). Group: Biochemicals. Grades: Highly Purified. CAS No. 519178-28-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Valiolamine Quick inquiry Where to buy Suppliers range | Valiolamine is an exceptional alkaloid compound, used for studying chronic myeloid leukemia (CML). By virtue of its extraordinary capability to impede tyrosine kinases, Valiolamine demonstrates unparalleled potency in studying leukemic manifestations. Synonyms: D-epi-Inositol, 4-amino-3,4-dideoxy-2-C-(hydroxymethyl)-; 4-Amino-3,4-dideoxy-2-C-(hydroxymethyl)-D-epi-inositol; EB 0155. Grades: ≥95%. CAS No. 83465-22-9. Molecular formula: C7H15NO5. Mole weight: 193.20. | |
Wortmannin Quick inquiry Where to buy Suppliers range | Antibiotic. Potent anti-neutrophil agent with cardioprotective effects. mTOR, DNA-PK, phosphatidylinositol 4-kinases, myosin light chain kinase (MLCK) and mitogen-activated protein kinase (MAPK) inhibitor at high concentrations. Potent cell permeable and selective inhibitor of phosphatidyl-inositol 3-kinase (PI3K). Antitumor compound. Radiosensitizing agent. Adipogenesis inhibitor. Angiogenesis inhibitor. Autophagy inhibitor. DNA repair, receptor-mediated endocytosis and cell proliferation inhibitor. Potentiates the LPS-induced nitric oxide (NO) production from macrophages. Induces in vivo Alzheimer-like hyperphosphorylation in tau. Polo-like kinase family inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 19545-26-7. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C23H24O8. US Biological Life Sciences. | Worldwide |