Interferon Suppliers USA
Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
Product | Description | |
---|---|---|
Interferon-a-IFNa-R Interaction Inhibitor (N-Methyl-1- (2- (naphthalen-1-ylthio) phenyl) methanamine, HCl, N-Methyl-N- (2- (1-naphthylthio) benzyl) amine, HCl, IFN-alpha Inhibitor) Quick inquiry Where to buy Suppliers range | A nonpeptidic thiophenylmethanamine compound that binds interferon-a (Kd= 4uM for human IFN-a) and prevents IFN-a and IFNAR interaction-dependent IFN-a production in murine BM-pDCs (bone marrow-derived plasmacytoid dendritic cells) cultures upon MVA infection (IC50<4.5uM), while exhibiting no inhibitory effect against IL-12 production in the same cultures when applied at non-toxic concentrations (<4.5uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Interferon alfa-2b Quick inquiry Where to buy Suppliers range | Interferon alfa-2b. Uses: For analytical and research use. Group: European Pharmacopoeia (Ph. Eur.); Pharmacopoeial Standards. CAS No. 98530-12-2. Molecular formula: C860H1353N229O255S9. Mole weight: 19268.91. Catalog: APS98530122. Format: Neat. Product Type: API. Shipping: Dry ice. | |
Interferon beta-1a Quick inquiry Where to buy Suppliers range | Interferon beta-1a. Uses: For analytical and research use. Group: European Pharmacopoeia (Ph. Eur.); Pharmacopoeial Standards. Alternative Names: Neoferon,Interferon β1 (human fibroblast protein moiety), Interferon beta-1a. CAS No. 145258-61-3. Molecular formula: C908H1406N246O252S7. Mole weight: 20024.83. Catalog: APS145258613. Format: Mixture. Product Type: API. Shipping: Dry ice. | |
Interferon Beta-1a Oxidised Peptide Quick inquiry Where to buy Suppliers range | Interferon Beta-1a Oxidised Peptide. Uses: For analytical and research use. Group: British Pharmacopoeia; Pharmacopoeial Standards. Catalog: APS009039. Format: Neat. Product Type: API. | |
Interferon gamma-1b Quick inquiry Where to buy Suppliers range | Interferon gamma-1b. Uses: For analytical and research use. Group: European Pharmacopoeia (Ph. Eur.); Pharmacopoeial Standards. CAS No. 98059-61-1. Molecular formula: C734H1166N204O216S5. Mole weight: 16464.67. Catalog: APS98059611. Format: Mixture. Product Type: API. Shipping: Dry ice. | |
Interferon gamma-1b for system suitability Quick inquiry Where to buy Suppliers range | Interferon gamma-1b for system suitability. Uses: For analytical and research use. Group: European Pharmacopoeia (Ph. Eur.); Pharmacopoeial Standards. CAS No. 98059-61-1. Molecular formula: C734H1166N204O216S5. Mole weight: 16464.67. Catalog: APS98059611A. Format: Mixture. Product Type: Other. Shipping: Ice pack (-20°C). | |
Interferon receptor agonist Quick inquiry Where to buy Suppliers range | Interferon receptor agonist. Group: Pheromone Ingredients. CAS No. 2215120-36-6. Molecular formula: C12H22N4O2. Mole weight: 254.33. | |
2',3'-cGAMP sodium salt Quick inquiry Where to buy Suppliers range | 2',3'-cGAMP sodium is an endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-&beta. 2',3'-cGAMP is an effective adjuvant that boosts the production of antigen-specific antibodies and T cell responses in mice. Synonyms: Cyclic [G(2',5')pA(3',5')p] sodium; cyclic GMP-AMP sodium; 2',3'-cyclic GMP-AMP sodium; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt. Grades: 95%. CAS No. 2734858-36-5. Molecular formula: C20H22N10Na2O13P2. Mole weight: 718.38. | |
AC 264613 Quick inquiry Where to buy Suppliers range | AC 264613 is a potent and selective protease-activated receptor 2 (PAR2) agonist (pEC50 = 7.5). AC 264613 inhibits interferon regulatory factor 5 and decreases interleukin-12p40 production via lipopolysaccharide-stimulated macrophages. PI hydrolysis, Ca2+ mobilization and cellular proliferation are activated by AC 264613 in vitro (pEC50 = 6.9, 7.0 and 7.5, respectively). Synonyms: AC-264613; AC 264613; AC264613; (±)-(3R,4S)-2-Oxo-4-phenyl-3-pyrollidinecarboxylic acid 2-[1-(3-bromophenyl)ethylidene]hydrazide. Grades: ≥98% by HPLC. CAS No. 1051487-82-1. Molecular formula: C19H18BrN3O2. Mole weight: 400.27. | |
ADU-S100 ammonium salt Quick inquiry Where to buy Suppliers range | ML RR-S2 CDA ammonium salt is an inducer of stimulator of interferon genes (STING). It can increases type I interferon production by THP-1 human monocytes relative to unmodified cyclic di-AMP, indicating the ML enhances its action at human STING. Synonyms: MIW815 ammonium salt; ML RR-S2 CDA ammonium salt; [P(R)]-5'-O-[(R)-hydroxymercaptophosphinyl]-P-thioadenylyl-(2'?5')-adenosine, cyclic nucleotide, diammonium salt; STING Inducer-1. Grades: 98%. CAS No. 1638750-96-5. Molecular formula: C20H30N12O10P2S2. Mole weight: 724.6. | |
ADU-S100 disodium salt Quick inquiry Where to buy Suppliers range | ADU-S100 disodium salt (MIW815 disodium salt) is an activator of stimulator of interferon genes (STING) for treating cancer. Synonyms: MIW815 disodium salt; ML RR-S2 CDA disodium salt; 2',3'-c-di-AM(PS)2 (Rp,Rp); Adenosine, [P(R)]-5'-O-[(R)-hydroxymercaptophosphinyl]-P-thioadenylyl-(2'?5')-, cyclic nucleotide, sodium salt (1:2); ADU-S 100; MIW 815. Grades: 98%. CAS No. 1638750-95-4. Molecular formula: C20H22N10Na2O10P2S2. Mole weight: 734.51. | |
Aloeemodin Quick inquiry Where to buy Suppliers range | Aloe-emodin is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71. Aloe-emodin has anti-tumor activity, antibacterial activity, immunosuppressive effect, and purgative effect. It is now widely used as a raw material for medicines and cosmetics. Uses: Antineuroectodermal tumor. Synonyms: 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione; 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone; 3-Hydroxymethylchrysazin; 3-Hydroxymethylchrysazine; Aloe-emodol; NSC 38628; Rhabarberone; Diacerein Impurity B. Grades: >98%. CAS No. 481-72-1. Molecular formula: C15H10O5. Mole weight: 270.24. | |
Aloe-emodin-[d5] Quick inquiry Where to buy Suppliers range | Aloe-emodin-[d5] is a labelled form of Aloe-emodin. Aloe-emodin is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71. Aloe-emodin has anti-tumor activity, antibacterial activity, immunosuppressive effect, and purgative effect. It is now widely used as a raw material for medicines and cosmetics. Synonyms: 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione-d5; 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone-d5; 3-Hydroxymethylchrysazin-d5; 3-Hydroxymethylchrysazine-d5; Aloe-emodol-d5; NSC 38628-d5; Rhabarberone-d5. CAS No. 1286579-72-3. Molecular formula: C15H5D5O5. Mole weight: 275.27. | |
Anifrolumab Quick inquiry Where to buy Suppliers range | Anifrolumab is a monoclonal antibody that blocks the activity of type I interferon (IFN). Anifrolumab has been investigated for the treatment of systemic lupus erythematosus (SLE). Synonyms: Saphnelo. CAS No. 1326232-46-5. | |
AP4A Quick inquiry Where to buy Suppliers range | AP4A is a signal molecule for DNA replication in mammalian cells. AP4A is used as a primer for oligoadenylate synthesis catalyzed by interferon-inducible 2-5A synthetase. AP4A is an inhibitor of eosinophil-derived neurotoxin (EDN). Uses: Ap4a is an inhibitor of eosinophil-derived neurotoxin (edn). Synonyms: (AppppA); P1-(5'-Adenosyl) P4-(5'-adenosyl) tetraphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 5542-28-9. Molecular formula: C20H28N10O19P4 (free acid). Mole weight: 836.39 (free acid). | |
Ascomycin Quick inquiry Where to buy Suppliers range | Ascomycin inhibits the production of T helper type 1 (Th1) (interferon and IL-2) and Th2 (IL-4 and IL-10) cytokines in target cells.Ascomycin (also known as Immunomycin, FR 900520, and FK-520) is an analog of tacrolimus (FK-506) with immunosuppressive, neurotrophic and antifungal activities. Ascomycin can be used to prevent rejection after an organ transplant, and to treat autoimmune diseases and skin diseases.Ascomycin inhibits the production of T helper type 1 (Th1) (interferon and IL-2) and Th2 (IL-4 and IL-10) cytokines in target cells. Paul, C., et al. "Ascomycins: promising agents for the treatment of inflammatory skin diseases." Expert Opin. Investig. Drugs. 9: 69-77 (2000). Mollison, K.W., et al. "A macrolactam inhibitor of T helper type 1 and T helper type 2 cytokine biosynthesis for topical treatment of inflammatory skin diseases." J. Invest. Dermatol. 112: 729-738 (1999).Antimalarial effects of ascomycin appear to be independent of its immunosuppressive properties. Monaghan, P., et al. "Antimalarial effects of macrolactones related to FK520 (ascomycin) are independent of the immunosuppressive properties of the compounds." J. Infect. Dis. 191: 1342-1349 (2005).FK-520 might be a substrate for P-glycoprotein; expression of P-glycoprotein in yeast cells resulted in resistance to growth inhibition by FK-520. Raymond, M., et al. "Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520." Mol. Cell Biol. 14: 277-286 (1994). Group: Biochemicals. Alternative Names: Immunomycin; FK-520; FR-520; NSC-106410; FR 900520; L 683590; Changchuanmycin. Grades: Highly Purified. CAS No. 104987-12-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C43H69NO12, Molecular Weight: 792.01. US Biological Life Sciences. | Worldwide |
Ascomycin (High Purity) (Immunomycin, FK520, Analog of FK-506, FR-900520, L-683590, NSC 106410, WS 7238A) Quick inquiry Where to buy Suppliers range | Macrolide antibiotic. Ethyl analog of FK506. Strong immunosuppressant. Binds to the FK-506-binding protein FKBP12. This complex inhibits calcineurin (protein phosphatase 2B (PP2B)). Suppresses the production of T helper type 1 (Th1) (interferon and IL-2) and Th2 (IL-4 and IL-10) cytokines in T lymphocytes and preferentially inhibits the activation of mast cells. Anti-inflammatory. Used for topical treatment of inflammatory skin diseases. Potently inhibits anti-IgE-induced histamine and cytokine release and reduces IgE-dependent p38 MAPK activation in human basophils. Inhibits basophil degranulation at the initial phase of allergic skin reactions. Antifungal. Antimalaria compound. Anticonvulsant (antiepileptic). Group: Biochemicals. Grades: Highly Purified. CAS No. 104987-12-4. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
Avridine Quick inquiry Where to buy Suppliers range | Avridine is a potent synthetic non-immunogenic adjuvant that used to induce arthritis in Lewis (LEW) and DA rats. Uses: A potent synthetic non-immunogenic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing. Synonyms: CP 20961; CP20961; CP-20961;N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane. Grades: ≥98%. CAS No. 35607-20-6. Molecular formula: C43H90N2O2. Mole weight: 667.19. | |
Avridine Quick inquiry Where to buy Suppliers range | A potent synthetic non-immunogenic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing. Group: Biochemicals. Alternative Names: 2, 2'- [ [3- (Dioctadecylamino) propyl] imino] bisethanol; CP 20961; CP-20961; N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane; N, N-Dioctadecyl-N', N'-bis (2-hydroxyethyl) propanediamine. Grades: Highly Purified. CAS No. 35607-20-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
bevacizumab-awwb Quick inquiry Where to buy Suppliers range | Bevacizumab-awwb is the first anti-cancer biosimilar and the first bevacizumab biosimilar approved for the treatment of five types of cancer, including in combination with chemotherapy for non-squamous non-small cell lung cancer (NSCLC), in combination with chemotherapy for metastatic colorectal cancer (mCRC), in combination with interferon alfa for glioblastoma, metastatic renal cell carcinoma and in combination with chemotherapy for persistent, recurrent, or metastatic carcinoma of the cervix. Uses: The traetment of nsclc, etc. Synonyms: Mvasi. | |
C-176 Quick inquiry Where to buy Suppliers range | C-176 is a highly potent and selective small-molecule antagonist of the stimulator of interferon genes (STING) protein. It is also a central signaling component of the intracellular DNA sensing pathway. Synonyms: STING inhibitor C 176; C176; C 176. Grades: ≥98%. CAS No. 314054-00-7. Molecular formula: C11H7IN2O4. Mole weight: 358.09. | |
C-178 Quick inquiry Where to buy Suppliers range | C-178 is a highly potent and selective small-molecule antagonist of the stimulator of interferon genes (STING) protein. It binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells. C-178 also blocks palmitoylation (PMA)-induced clustering of STING. It inhibits the CMA-induced phosphorylation of TBK1, which is downstream protein kinase of STING. C-178 prevents the increases in Ifnb1 expression in bone marrow-derived macrophages (BMDMs). Synonyms: C178; C 178. Grades: ≥98%. CAS No. 329198-87-0. Molecular formula: C17H10N2O5. Mole weight: 322.27. | |
c-(Ap-8-AET-Gp) Quick inquiry Where to buy Suppliers range | c-(Ap-8-AET-Gp) is an analogue of messenger c-(ApGp), the bacterial second, which is used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. c-(ApGp) plays a role in Vibrio choleraepathogenesis and activates the production of interferon via STING. Synonyms: Cyclic (adenosine monophosphate- 8- (2- aminoethylthio)guanosine monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C22H29N11O13P2S (free acid). Mole weight: 749.6 (free acid). | |
c-(Ap-8-Br-Gp) Quick inquiry Where to buy Suppliers range | c-(Ap-8-Br-Gp) is an analogue of c-(ApGp), the potential bacterial second messenger, which is used for binding studies and as precursor for further modifications with spacers or labels. c-(ApGp) plays a role in Vibrio choleraepathogenesis and activates the production of interferon via STING. Synonyms: Cyclic (adenosine monophosphate- 8- bromoguanosine monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H23BrN10O13P2 (free acid). Mole weight: 753.3 (free acid). | |
c-(Ap-8-Fluo-AET-Gp) Quick inquiry Where to buy Suppliers range | c-(Ap-8-Fluo-AET-Gp) is a fluorescent analogue of c-(ApGp), which can participate in Vibrio choleraepathogenesis and stimulate the production of interferon. Synonyms: Cyclic(adenosine monophosphate-8- (2-[fluoresceinyl]aminoethylthio) guanosine monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C43H39N11O19P2S (free acid). Mole weight: 1107.9 (free acid). | |
c-(ApIp) Quick inquiry Where to buy Suppliers range | c-(ApIp) is a STING (stimulator of interferon genes)-activating synthetic cyclic dinucleotide (CDN). Synonyms: 3'-Inosinic acid, adenylyl-(3'?5')-, cyclic nucleotide; Cyclic (adenosine monophosphate-inosine monophosphate); cAIMP; CL592; 9-((2R, 3R, 3aS, 7aR, 9R, 10R, 10aS, 14aR)-9-(6-amino-9H-purin-9-yl)-3, 5, 10, 12-tetrahydroxy-5, 12-dioxidooctahydro-2H, 7H-difuro[3, 2-d:3', 2'-j][1, 3, 7, 9]tetraoxa[2, 8]diphosphacyclododecin-2-yl)-1, 9-dihydro-6H-purin-6-one; 1-(6-Amino-9H-purine-9-yl)-1'-(6-hydroxy-9H-purine-9-yl)[3-O,5'-O-(hydroxyphosphinylidene)-5-O,3'-O-(hydroxyphosphinylidene)bis(1-deoxy-beta-D-ribofuranose)]; 3',3'-cAIMP; 3',3'-c(ApIp). Grades: ≥ 95% by HPLC. CAS No. 1507367-51-2. Molecular formula: C20H23N9O13P2. Mole weight: 659.40. | |
c-di-AMP Quick inquiry Where to buy Suppliers range | c-di-AMP is an agonist of stimulator of interferon genes (STING) for treating cancer. It is a second messenger in bacteria and archaea that is involved in the maintenance of osmotic pressure, response to DNA damage, and control of central metabolism, biofilm formation, acid stress resistance, and other functions. Synonyms: Cyclic diadenylate monophosphate; Cyclic diadenylate; Adenylic acid, cyclic ester; 3',5'-Cyclic diadenylic acid; Cyclic di-3',5'-adenylate; Cyclic di-AMP; Cyclic-di-AMP; Cyclic diadenosine monophosphate; (2R, 3R, 3aS, 7aR, 9R, 10R, 10aS, 14aR)-2, 9-bis(6-amino-9H-purin-9-yl)-3, 5, 10, 12-tetrahydroxyoctahydro-2H, 7H-difuro[3, 2-d:3', 2'-j][1, 3, 7, 9]tetraoxa[2, 8]diphosphacyclododecine 5,12-dioxide. Grades: ≥95%. CAS No. 54447-84-6. Molecular formula: C20H24N10O12P2. Mole weight: 658.41. | |
Chlorcyclizine hydrochloride Quick inquiry Where to buy Suppliers range | Chlorcyclizine is a phenylpiperazine that acts as a histamine H1 receptor antagonist (Ki = 9 nM). It is believed to be effective against hepatitis C virus (HCV; EC50 = 44 nM in vitro), targeting viral entry into host cells. Chlorcyclizine showed a synergistic effect with other hepatitis C drugs such as ribavirin, interferon, telaprevir, boceprevir, sofosbuvir, daclatasvir, and cyclosporin A. Synonyms: NSC 169496; Chlorcyclizine HCl; 1-[(4-chlorophenyl)phenylmethyl]-4-methyl-piperazine monohydrochloride. Grades: ≥98%. CAS No. 14362-31-3. Molecular formula: C18H21ClN2·HCl. Mole weight: 337.3. | |
CL656 Quick inquiry Where to buy Suppliers range | CL656 is an agonist of stimulator of interferon genes (STING) for treating cancer. Synonyms: c-[2'FdAMP(S)-2'FdIMP(S)]; cAIM(PS)2 Difluor (Rp/Sp); Adenosine, 2'-deoxy-2'-fluoro-5'-O-(hydroxymercaptophosphinyl)-P-thioinosinylyl-(3'?5')-2'-deoxy-2'-fluoro-, cyclic nucleotide; CL 656; CL-656; (Rp/Sp) c-[2'FdAM(PS)-2'FdIM(PS]); 9-((2R, 3R, 3aR, 7aR, 9R, 10R, 10aR, 14aR)-9-(6-amino-9H-purin-9-yl)-3, 10-difluoro-12-hydroxy-5-mercapto-5-oxido-12-sulfidooctahydro-2H, 7H-difuro[3, 2-d:3', 2'-j][1, 3, 7, 9]tetraoxa[2, 8]diphosphacyclododecin-2-yl)-1, 9-dihydro-6H-purin-6-one. Grades: >98%. CAS No. 1951464-79-1. Molecular formula: C20H21F2N9O9P2S2. Mole weight: 695.51. | |
diABZI STING agonist-1 Quick inquiry Where to buy Suppliers range | diABZI STING agonist-1 is a selective agonist of stimulator of interferon genes (STING) receptor, with EC50s of 130, 186 nM for human and mouse, respectively. Synonyms: 1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-[3-(4-morpholinyl)propoxy]-; (E)-1-(4-(5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzo[d]imidazole-5-carboxamide; STING agonist compound 3; 1-[(2E)-4-[5-(Aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-[3-(4-morpholinyl)propoxy]-1H-benzimidazole-5-carboxamide. Grades: >98%. CAS No. 2138299-33-7. Molecular formula: C42H51N13O7. Mole weight: 849.94. | |
Dinactin Quick inquiry Where to buy Suppliers range | A member of the macrotetrolide complex produced by a range of streptomyces species; a monovalent cation ionophore with high selectivity for ammonium and potassium; inhibits T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and interferon-&gamma. It is also resistant to gram-positive bacteria and mycobacteria. Synonyms: GNF-Pf-90; Antibiotic 170t; NSC63925; 4, 13, 22, 31, 37, 38, 39, 40-Octaoxapentacyclo(32.2.1.17, 10.116, 19.125, 28)tetracontane-3, 12, 21, 30-tetrone, 5,23-diethyl-2,11,14,20,29,32-hexamethyl-(VAN) (8CI). Grades: >95% by HPLC. CAS No. 20261-85-2. Molecular formula: C42H68O12. Mole weight: 764.98. | |
Dinactin (Antibiotic AKD 1C, Antibiotic S 3466A) Quick inquiry Where to buy Suppliers range | Dinactin is a member of the macrotetrolide complex produced by a range of Streptomyces species. It is a monovalent cation ionophore with high selectivity for ammonium and potassium. Dinactin inhibited T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and interferon-g. Dinactin has not previously been available for intensive investigation. Group: Biochemicals. Alternative Names: Antibiotic AKD 1C, Antibiotic S 3466A. Grades: Highly Purified. CAS No. 20261-85-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
(D)-(+)-Neopterin Quick inquiry Where to buy Suppliers range | Neopterin, a pyrazino-pyrimidine compound derived from GTP, n is a precursor of tetrahydrobiopterin and can be used as a biochemical marker indicative of cell proliferation. Neopterin is synthesized in response to interferon-γ stimulation, and used as a marker of T helper cell-induced immune activation. Neopterin is also an indicator of oxidative stress, and modulates the effects of reactive oxygen species (ROS). Synonyms: 2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone; Neopterin; 2-Amino-4-hydroxy-6-(1,2,3-trihydroxypropyl)pteridine; 2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)-4(8H)-pteridone; 6-D-erythro-Neopterin; D-(+)-Neopterin; D-erythro-Neopterin. Grades: ≥98% by HPLC. CAS No. 2009-64-5. Molecular formula: C9H11N5O4. Mole weight: 253.21. | |
Emapalumab Quick inquiry Where to buy Suppliers range | Emapalumab is an anti-interferon-gamma (IFNγ) monoclonal antibody approved for the treatment of primary hemophagocytic lymphohistiocytosis (HLH). Synonyms: Gamifant; NI-0501; NI 0501; NI0501. CAS No. 1709815-23-5. | |
Frenlosirsen Quick inquiry Where to buy Suppliers range | Frenlosirsen is an interferon regulatory factor 4 (IRF4) synthesis reducer, with antineoplastic properties. Synonyms: all-P-ambo-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-P-thioadenylyl-(3'?5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-P-thioguanylyl-(3'?5')-P-thiothymidylyl-(3'?5')-P-thiothymidylyl-(3'?5')-2'-deoxy-P-thioguanylyl-(3'?5')-P-thiothymidylyl-(3'?5')-2'-deoxy-P-thioadenylyl-(3'?5')-2'-deoxy-P-thioadenylyl-(3'?5')-2'-deoxy-P-thioadenylyl-(3'?5')-P-thiothymidylyl-(3'?5')-2'-deoxy-P-thioguanylyl-(3'?5')-2'-O-(2-methoxyethyl)-P-thioadenylyl-(3'?5')-2'-O-(2-methoxyethyl)-P-thioguanylyl-(3'?5')-2'-O-(2-methoxyethyl)-5-methyl-P-thiouridylyl-(3'?5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-5-methyl-P-thiocytidylyl-(3'?5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]guanosine; DNA, d(P-thio)((2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-alpha-L-mannofurano)A-(3'->4')-(2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-alpha-L-mannofurano)G-T-T-G-T-A-A-A-T-G-(2'-O-(2-methoxyethyl))rA-(2'-O-(2-methoxyethyl))rG-(2'-O-(2-methoxyethyl))m5rU-(3'->4')-(2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-alpha-L-mannofurano)m5C-(3'->4')-(2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-alpha-L-mannofurano)G). CAS No. 2304711-81-5. Molecular formula: C177H226N63O89P15S15. Mole weight: 5605.71. | |
Golotimod Quick inquiry Where to buy Suppliers range | Golotimod is an orally bioactive synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by a gamma-glutamyl linkage with potential immunostimulating, antimicrobial and antineoplastic activities. Golotimod has been shown to inhibit the expression of STAT-3, reversing immunosuppression and stimulating an anti-tumor immune response. It may stimulate the production of T-lymphocytes (in particular the helper T [Th1] cells), activate macrophages, and increase levels of interleukin 2 and interferon gamma. Synonyms: SCV-07; Gamma-D-Glu-L-trp; SCV07; SCV 07; Gamma-D-Glutamyl-L-tryptophan; (2R)-2-amino-5-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid. Grades: >98%. CAS No. 229305-39-9. Molecular formula: C16H19N3O5. Mole weight: 333.34. | |
IACS-8779 Quick inquiry Where to buy Suppliers range | IACS-8779 is a highly potent agonist of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. IACS-8779 shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma when compared to one of the clinical benchmark compounds. Synonyms: SCHEMBL23046679; 2243079-26-5; AKOS040733407. Grades: >98%. CAS No. 2243079-26-5. Molecular formula: C21H25N9O10P2S2. Mole weight: 689.56. | |
IACS-8803 Quick inquiry Where to buy Suppliers range | IACS-8803 is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. Compared to one of the clinical benchmark compounds, it shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma. Synonyms: CHEMBL4596454; SCHEMBL22930678; SCHEMBL23710564; 2095690-70-1; AKOS040733408. Grades: >98%. CAS No. 2095690-70-1. Molecular formula: C20H23FN10O9P2S2. Mole weight: 692.53. | |
IFN-γ Antagonist Quick inquiry Where to buy Suppliers range | IFN-γ Antagonist, derived from the ligand binding site of human γ-interferon (IFN-γ) receptor, is an antagonist of human IFN-γ, and inhibits human IFN-γ-induced expression of HLR/DR antigen on Colo 205 cells with an IC50 of about 35 μM. Synonyms: (Tyr121,Cys(Acm)122)-IFN-γ Receptor (120-141) (human); L-Isoleucine, L-alanyl-L-tyrosyl-S-[(acetylamino)methyl]-L-cysteinyl-L-arginyl-L-α-aspartylglycyl-L-lysyl-L-isoleucylglycyl-L-prolyl-L-prolyl-L-lysyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-arginyl-L-lysyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-glutaminyl-; L-alanyl-L-tyrosyl-S-acetamidomethyl-L-cysteinyl-L-arginyl-L-alpha-aspartyl-glycyl-L-lysyl-L-isoleucyl-glycyl-L-prolyl-L-prolyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-arginyl-L-lysyl-L-alpha-glutamyl-L-alpha-glutamyl-L-lysyl-L-glutaminyl-L-isoleucine; H-Ala-Tyr-Cys(Acm)-Arg-Asp-Gly-Lys-Ile-Gly-Pro-Pro-Lys-Leu-Asp-Ile-Arg-Lys-Glu-Glu-Lys-Gln-Ile-OH. Grades: ≥95%. CAS No. 158040-83-6. Molecular formula: C115H194N34O34S. Mole weight: 2629.04. | |
Imiquimod Quick inquiry Where to buy Suppliers range | An agonist of TLR7 with immune response modifying activity, Approved for basal cell carcinoma, In Phase III for VIN and CIN, Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells. Uses: An immune response modifier. it stimulates the production of interferon-a. Synonyms: 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; R-837; S-26308; Aldara; TMX-101; 1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-; 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine; 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-ylamine; Aldara; Beselna; Keravort; R 837; R837; S 26308; TMX 101; Zartra; Zyclara. Grades: >98%. CAS No. 99011-02-6. Molecular formula: C14H16N4. Mole weight: 240.30. | |
Imiquimod Quick inquiry Where to buy Suppliers range | Cell-permeable. Topical immune response modifier that displays anti-angiogenic, anti-viral and anti-inflammatory properties. Up-regulates IL-18 and down-regulates MMP-9 through recognition of Toll-like receptor 7 (TLR7) and subsequent activation of MyD88-dependent pathway. Stimulates proinflammatory cytokine production interferon-alpha (IFN-alpha), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) and activates NF-kappaB. Caspase-3 activator that directly induces procaspase-3 cleavage. Anti-cancer compound. Apoptosis inducer. Antiproliferative, independent of immune system activation or function. Approved treatment for external genital warts caused by human papillomavirus infection. Group: Biochemicals. Alternative Names: 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; R-837; S-26308. Grades: Highly Purified. CAS No. 99011-02-6. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C14H16N4. US Biological Life Sciences. | Worldwide |
Imiquimod Impurity 2 Quick inquiry Where to buy Suppliers range | Imiquimod Impurity 2 is an immune response modifier. It stimulates the production of interferon-a. Synonyms: 3-Hydroxy Imiquimod; 4-Amino-β-methyl-1H-imidazo[4,5-c]quinoline-1-propanol. Grades: > 95%. CAS No. 1807606-78-5. Molecular formula: C14H16N4O. Mole weight: 256.30. | |
Imiquimod Impurity 4 Quick inquiry Where to buy Suppliers range | Imiquimod Impurity 4 is one of Imiquimod impurities, Imiquimod is an immune response modifier. It stimulates the production of interferon-a. Molecular formula: C15H16N4O. Mole weight: 268.31. | |
Imiquimod Impurity 5 Quick inquiry Where to buy Suppliers range | Imiquimod Impurity 5 is one of Imiquimod impurities, Imiquimod is an immune response modifier. It stimulates the production of interferon-a. CAS No. 853793-02-9. Molecular formula: C15H18N4. Mole weight: 254.33. | |
Imiquimod Impurity 6 Quick inquiry Where to buy Suppliers range | Imiquimod Impurity 6 is one of Imiquimod impurities, Imiquimod is an immune response modifier. It stimulates the production of interferon-a. CAS No. 99010-99-8. Molecular formula: C14H15N3O. Mole weight: 241.29. | |
Ionomycin (Free Acid) Quick inquiry Where to buy Suppliers range | Antibiotic. Potent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators. Ionomycin also transports Pb2+ and some other divalent cations, as well as several lanthanide series trivalent cations at efficiencies that are greater than or equal to those for Ca2+. Apoptosis inducer. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest at G1 phase and induces central demyelination. Used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2 and IL-4 usually in conjunction with PMA. ADAM10 agonist. Potent inducer of shedding CXCL16. TREK-1 channels inhibitor. PPARy ligand with a unique binding mode. Shows effective glucose-lowering activity in a mouse model of diabetes. Group: Biochemicals. Alternative Names: SQ 23377; EM 94; [2S-[2α[2S*, 5R*(S*)], 5 β(4S*, 6R*, 8R*, 10Z, 12S*, 14S*, 16E, 18S*, 19S*, 20R*, 21R*)]]-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[octahydro-5-(1-hydroxyethyl)-2, 5-dimethyl[2, 2-bifuran]-5-yl]-9-oxo-10, 16-docosadienoic Acid; [2S-[2α[2S*, 5R*(S*)], 5 β(4S*, 6R*, 8R*, 10Z, 12S*, 14S*, 16E, 18S*, 19S*, 20R*, 21R*)]]-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[octahydro-5-(1-hydroxyethyl)-2, 5-dimethyl[2, 2-bifuran]-5-yl]-9-oxo-10, 16-docosadienoic Acid; (4R, 6S, 8S, 10Z, 12R, 14R, 16E, 18R, 19R, 20S, 21S)-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[(2S, 2R, 5S, 5S)-octahydro-5-[(1R)-1-hydroxyethyl]-2, 5-dimethyl[2, 2-bifuran]-5-yl]-9-oxo-10, 16-docosadienoic Acid. Grades: Highly Purified. CAS No. 56092-81-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
Mesopram Quick inquiry Where to buy Suppliers range | Mesopram is an orally active, selective phosphodiesterase (PDE) 4 inhibitor. In vitro, mesopram selectively inhibits the activity of type 1 helper T (Th1) cells without affecting cytokine production or proliferation of type 2 helper T (Th2) cells. It decreases the synthesis of tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma). Some studies conclude that the specific type-4 phosphodiesterase inhibitor mesopram ameliorates murine colitis both in a preventive and a therapeutic setting. Synonyms: (R)-5-(4-Methoxy-3-propoxyphenyl)-5-methyl-2-oxazolidinone. Grades: ≥98% by HPLC. CAS No. 189940-24-7. Molecular formula: C14H19NO4. Mole weight: 265.31. | |
Monactin (5-demethyl-5-ethylnonactin, Antibiotic AKD 1B) Quick inquiry Where to buy Suppliers range | Monactin is a member of the macrotetrolide complex produced by a range of Streptomyces species. Unlike nonactin, monactin has not previously been available for intensive investigation. Early literature reported that the related dinactin is a monovalent cation ionophore with high selectivity for ammonium and potassium. Monactin inhibits T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and interferon-gamma. Group: Biochemicals. Alternative Names: 5-demethyl-5-ethylnonactin, Antibiotic AKD 1B. Grades: Highly Purified. CAS No. 7182-54-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
N-Formyl Imiquimod Quick inquiry Where to buy Suppliers range | N-Formyl Imiquimod is one of Imiquimod impurities, Imiquimod is an immune response modifier. It stimulates the production of interferon-a. Synonyms: N-[1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-yl]-formamide. CAS No. 910644-52-9. Molecular formula: C15H16N4O. Mole weight: 268.31. | |
Polyinosinic-polycytidylic acid sodium salt Quick inquiry Where to buy Suppliers range | Polycytidylic acid sodium salt is a biomedical product used for developing immune stimulant and antiviral drugs. It is commonly used in research to induce interferon production, enabling the study of immune responses in vitro. Additionally, it has potential applications in studying viral infections, such as hepatitand HIV. Synonyms: Poly(I:C) sodium salt; 5'-Inosinic acid, homopolymer, complex with 5'-cytidylic acid homopolymer, sodium salt (1:1:x); 5'-Cytidylic acid, homopolymer, complex with 5'-inosinic acid homopolymer, sodium salt; 5'-Inosinic acid, homopolymer, complex with 5'-cytidylic acid homopolymer, sodium salt; Polyinosinic acid-polycytidylic acid sodium salt; Poly I-poly C sodium salt; Poly(I:C) (Polyinosinic-Polycytidylic) sodium salt. CAS No. 42424-50-0. Molecular formula: (C10H13N4O8P)x.(C9H14N3O8P)x.xNa. | |
Pravastatin Quick inquiry Where to buy Suppliers range | Pravastatin is an antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase with IC50 of 5.6 μM. It is used in combination with diet, exercise, and weight loss for lowering cholesterol and preventing cardiovascular disease. It is a synthetic lipid-lowering agent. It lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing major histocompatibility complex II on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. It is primarily used for the treatment of dyslipidemia and the prevention of cardiovascular disease. It is used to reduce LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease. Uses: Pravastatin acts as a competitive inhibitor of hmg coa reductase. it is a synthetic lipid-lowering agent. it is primarily used for the treatment of dyslipidemia and the prevention of cardiovascular disease. it is used to reduce ldl cholesterol and triglyceride levels and increase hdl cholesterol in the prevention of cardiovascular disease. Synonyms: 1-Naphthaleneheptanoicacid, 1, 2, 6, 7, 8, 8a-hexahydro-b, d, 6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, [1S-[1a(bS*, dS*), 2a, 6a, 8b(R*), 8aa]]-; 3b-Hydroxycompactin; Eptastatin; Mevalothin; Pravastatin acid;Pravachol; Pravastatina; Pravastatine; Pravastatinum; (3R, 5R)-7-[(1S, 2S, 6S, 8S, 8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1, 2, 6, 7, 8, 8a-hexahydronaphthalen-1-yl]-3, 5-dihydroxyheptanoic acid. Grades: 98%. CAS No. 81093-37-0. Molecular formula: C23H36O7. Mole weight: 424.53. | |
RO8191 Quick inquiry Where to buy Suppliers range | RO8191 is an agonist of interferon α receptor type 2 (IFNAR2) effective against HCV with EC50 value of 200 nM. RO8191 phosphorylates STAT1 and STAT2, which functions as a gateway to the type I IFN signal cascade, and stimulates the phosphorylation of STAT3, 5 and 6. Synonyms: Ro 494-8191; 2-[2,4-bis(trifluoromethyl)imidazo[1,2-a]1,8-naphthyridin-8-yl]-1,3,4-oxadiazole; 8-(1,3,4-oxadiazol-2-yl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine. Grades: ≥98%. CAS No. 691868-88-9. Molecular formula: C14H5F6N5O. Mole weight: 373.2. | |
(R)-PK11195 Quick inquiry Where to buy Suppliers range | PK 11195, 85532-75-8, PK11195, 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide, PK-11195, RP 52028, UNII-YNF83VN1RL, YNF83VN1RL, 85340-56-3, BRN 4264456, DTXSID7041097, CHEBI:73290, 3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-, N-butan-2-yl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide, N-sec-butyl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide, PK11195,(R)-(-)-, C21H21ClN2O, N-(butan-2-yl)-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide, N-(sec-Butyl)-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide, (R)-PK11195, SMR000058427, SR-01000076240, 205934-46-9, Biomol-NT_000287, D03NOO, D0VN4K, Lopac0_000198, Interferon alfa (IFN-alpha), MLS000028483, MLS006010699, CHEMBL15313, SCHEMBL117124, BPBio1_001278, CHEMBL481537, GTPL8703, DTXCID5021097, BDBM22032, HMS2234C05, HMS3260H17, HMS3266H15, HMS3372J02, HMS3411O10, HMS3675O10, HMS3870J13, EX-A2448, Tox21_300620, Tox21_500198, HB0922, PDSP1_000637, PDSP2_000632, AKOS024458600, CCG-204293, LP00198, SDCCGSBI-0050186.P002, NCGC00015205-03, NCGC00015205-04, NCGC00015205-05, NCGC00015205-06, NCGC00015205-07, NCGC00015205-08, NCGC00015205-14, NCGC00024720-02, NCGC00024720-03, NCGC00024720-04, NCGC00254354-01, NCGC00260883-01, [3H]PK 11195, BM166506, HY-19567, LS-85394, MS-25479, RP-52028, CAS-85532-75-8, CS-0015789, EU-0100198, FT-0724157, PK-11195; RP-52028, C 0424, E98630, 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl), Q7119490, SR-01000076240-1, SR-01000076240-3, BRD-A41451487-001-01-3, BRD-A41451487-001-04-7, 1-(2-Chloro-phenyl)-isoquinoline-3-carboxylic acid sec-butyl-methyl-amide, N-METHYL-N-(1-METHYLPROPYL)-1-(2-CHLOROPHENYL)ISOQUINOLINE-3-CARBOXAMIDE, (R)PK-11195, N-[(2r)-Butan-2-Yl]-1-(2-Chlorophenyl)-N-Methylisoquinoline-3-Carboxamide, 1-(2-Chlorophenyl)-N-methyl-N-[(1R)-1-methylpropyl]-3-isoquinolinecarboxamide, (R)-PK11195, 205934-46-9, D0O6JQ, CHEMBL416715, SCHEMBL3126094, BDBM50054139, LS-85395, Q27464457, (r)-n-methyl-n-(1-methylpropyl)-1-(2-chlorophenyl)isoquinoline-3-carboxamide, (R)1-(2-Chloro-phenyl)-isoquinoline-3-carboxylic acid sec-butyl-methyl-amide. | |
SR-717 lithium Quick inquiry Where to buy Suppliers range | SR-717 is an agonist of stimulator of interferon genes (STING) for treating cancer. Synonyms: SR 717 lithium; SR717 lithium. Grades: >98%. CAS No. 2375421-09-1. Molecular formula: C15H8F2LiN5O3. Mole weight: 351.2. | |
STING-agonist-3 Quick inquiry Where to buy Suppliers range | STING-agonist-3 is an agonist of stimulator of interferon genes (STING) for treating cancer. Synonyms: (E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-hydroxypropoxy)-1H-benzo[d]imidazole-5-carboxamide. Grades: 99%. CAS No. 2138299-29-1. Molecular formula: C37H42N12O6. Mole weight: 750.8. | |
STING agonist-3-trihydrochloride Quick inquiry Where to buy Suppliers range | STING agonist-3-trihydrochloride is an agonist of stimulator of interferon genes (STING) for treating cancer. Grades: ≥98%. Molecular formula: C37H45Cl3N12O6. Mole weight: 860.19. | |
STING-agonist-4 Quick inquiry Where to buy Suppliers range | STING-agonist-4 is an agonist of stimulator of interferon genes (STING) for treating cancer. Synonyms: 1,1'-(butane-1,4-diyl)bis{2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-1H-benzimidazole-5-carboxamide}. Grades: 99%. CAS No. 213830-40-8. Molecular formula: C34H38N12O4. Mole weight: 678.74. | |
STING Agonist C11 Quick inquiry Where to buy Suppliers range | STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway. It activates IFN-dependent signaling and induces secretion of IFN from human cells. Synonyms: N-(Methylcarbamoyl)-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-2-phenylacetamide. Grades: ≥95%. CAS No. 875863-22-2. Molecular formula: C19H18N4O3S. Mole weight: 382.44. | |
STING-IN-3 Quick inquiry Where to buy Suppliers range | STING-IN-3 is an inhibitor of interferon gene stimulator (STING). Synonyms: 2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro-; N-(4-Hexylphenyl)-5-Nitro-2-Furancarboxamide. Grades: 98%. CAS No. 2244881-69-2. Molecular formula: C17H20N2O4. Mole weight: 316.35. | |
Tilorone dihydrochloride Quick inquiry Where to buy Suppliers range | Tilorone dihydrochloride, as a broad-spectrum, orally active antiviral agent, is an orally active interferon inducer. Synonyms: 2,7-bis[2-(diethylamino)ethoxy]fluoren-9-one;dihydrochloride. Grades: ≥ 98 %. CAS No. 27591-69-1. Molecular formula: C25H34N2O3 · 2HCl. Mole weight: 483.47. | |
Trinactin Quick inquiry Where to buy Suppliers range | Trinactin is a tetracyclic lactone compound produced by Streptomyces. It is a monovalent cation ionophore with high selectivity to ammonium and potassium. It can inhibit the proliferation of T cells induced by IL-2, and inhibit the production of cytokines at nanomolar levels of IL-2, IL-4, IL-5 and interferon-&gamma. Synonyms: AKD-1D; S 3466B. Grades: >95% by HPLC. CAS No. 7561-71-9. Molecular formula: C43H70O12. Mole weight: 779.0. | |
Trinactin (Antibiotic AKD-1D, Antibiotic S 3466B) Quick inquiry Where to buy Suppliers range | Trinactin is a member of the macrotetrolide complex produced by a range of Streptomyces sp. Early literature reported that trinactin is a monovalent cation ionophore with high selectivity for ammonium and potassium. Trinactin inhibited T-cell proliferation induced by IL-2 and cytokine production at nonomolar levels for IL-2, IL-4, IL-5 and interferon-gamma. Trinactin has not previously been available for intensive investigation. Group: Biochemicals. Alternative Names: Antibiotic AKD-1D, Antibiotic S 3466B. Grades: Highly Purified. CAS No. 7561-71-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |