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2'-O-(tert-Butyldimethylsilyl)-6α-hydroxy 7-epi-Paclitaxel 2'-O-(tert-Butyldimethylsilyl)-6α-hydroxy 7-epi-Paclitaxel is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Uses: 6α-hydroxypaclitaxel derivative. Synonyms: (3xi, 5beta, 6alpha, 7alpha, 10beta, 13alpha)-4, 10-Bis(acetyloxy)-13-{[(2R, 3S)-3-benzamido-2-{[tert-butyl(dimethyl)silyl]oxy}-3-phenylpropanoyl]oxy}-1, 6, 7-trihydroxy-9-oxo-5, 20-epoxytax-11-en-2-yl benzoate; 2-tert-Pentylcyclopentanon; 2-(1,1-dimethyl-propyl)-cyclopentan-1-one; 2'-NOR THIAMINE; 2-t-Amyl-cyclopentanon; (2aR, 3S, 4S, 4aS, 6S, 9S, 11S, 12S, 12aR, 12bS)-9-(((2R, 3S)-3-benzamido-2-((tert-butyldimethylsilyl)oxy)-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-3, 4, 11-trihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-d3, 4]benzo[1, 2-b]oxete-6, 12b-diyl diacetate. Grades: > 98%. CAS No. 165065-08-7. Molecular formula: C53H65NO15Si. Mole weight: 984.16. BOC Sciences 7
Alarelin acetate Alarelin acetate is a synthetic Gonadotrophin-releasing hormone agonist. It is the acetate form of a hypothalamic peptide. It is a potent LH-RH agonist in rats and mice. It reversibly delays sexual maturation in rats, stimulates spawning activity in fish. It could inducte ovulation and is used to treat endmometriosis. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Uses: Alarelin acetate could inducte ovulation and is used to treat endmometriosis. it is responsible for the secretion of gonadotropins, luteinizing hormone (lh) and follicle-stimulating hormone (fsh), from the pituitary glands. Synonyms: LHRH-A; 6-D-Ala-10-D-gly-LHRH-ethylamide; Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt; 6-D-Ala-10-D-gly-LHRH-ethylamide; (S)-1-((3S,6S,9S,12S,15R,18S,21S)-3-((1H-imidazol-5-yl)methyl)-6-((1H-indol-3-yl)methyl)-21-(3-((diaminomethylene)amino)propyl)-12-(4-hydroxybenzyl)-9-(hydroxymethyl)-18-isobutyl-15-methyl-1,4,7,10,13,16,19-heptaoxo-1-((S)-5-oxopyrrolidin-2-yl)-2,5,8,11,14,17,20-heptaazadocosan-22-oyl)-N-ethylpyrrolidine-2-carboxamide diacetate. Grades: >98%. CAS No. 79561-22-1. Molecular formula: C60H86N16O16. Mole weight: 1287.42. BOC Sciences
BRL-37344 sodium BRL37344 is a selective β3-adrenergic receptor agonist originated by GlaxoSmithKline. Ki value is 287nM for β3 receptor, 1750nM for β1 receptor and 1120nM for β2 receptor. BRL37344 can decrease nerve-evoked contractions in human detrusor smooth muscle isolated strips, it can also stimulate fuel oxidation by soleus muscle in vitro. BRL37344 increases glucose transport into L6 myocytes through a mechanism different from that of insulin. But preclinical for Diabetes mellitus was discontinued. Uses: Diabetes mellitus. Synonyms: BRL-37344 sodium; BRL 37344 sodium; BRL37344 sodium; sodium; 2- [4- [ (2R) -2- [ [ (2R) -2- (3-chlorophenyl) -2-hydroxyethyl] amino] propyl] phenoxy] acetate. Grades: 98 %. CAS No. 127299-93-8. Molecular formula: C19H21ClNNaO4. Mole weight: 385.82. BOC Sciences 10
Zuclopenthixol acetate Zuclopenthixol is a typical antipsychotic drug that belongs to thioxanthene class. Zuclopenthixol is the cis-isomer of clopenthixol. Zuclopenthixol has not been approved for use in the United States. It is a dopamine D1/D2 receptor antagonist used for the treatment of Schizophrenia. Uses: Schizophrenia. Synonyms: (Z)-4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)piperazine-1-ethyl acetate; Clopixol-Acuphase. Grades: 98%. CAS No. 85721-05-7. Molecular formula: C24H27ClN2O2S. Mole weight: 443.01. BOC Sciences 8
2,3,4-Tri-O-acetyl- β-D-glucuronic Acid Methyl Ester Propan-2-ol-D6 2,3,4-Tri-O-acetyl- β-D-glucuronic Acid Methyl Ester Propan-2-ol-D6 is an intermediate in the synthesis of Propylene Glycol-d6 1-Glucuronide (Mixture of Diastereomers) Sodium Salt (P835237). Isotope labelled Propylene Glycol 1-Glucuronide is a metabolite of propylene glycol, used in the synthesis of N-terminal kinase inhibitors with cellular activity. Acts as a solvent for various pharmaceutical compounds. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H18D6O11. US Biological Life Sciences. USBiological 10
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9-Desmethyl-alpha-Dihydro-Tetrabenazine 9-Desmethyl-alpha-Dihydro-Tetrabenazine is one of Tetrabenazine derivatives. Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Synonyms: (+)-9-O-Desmethyl-a-dihydrotetrabenazine; 1H-Naphtho[2,3-c]pyran-3-aceticacid,3,4,5,10-tetrahydro-9-hydroxy-5,10-dioxo-1-propyl-,(1R,3S); Desoxyfrenolicin; (2R,3R,11bR)-9-O-desmethyldihydrotetrabenazine; (+)-deoxyfrenolicin; 1H-Naphtho(2,3-c)pyran-3-acetic acid,3,4,5,10-tetrahydro-9-hydroxy-5,10-dioxo-1-propyl-,(1R-trans); 9-o-Desmethyl-alpha-dihydrotetrabenazine; 3-isobutyl-10-methoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline-2,9-diol. Grades: ≥95%. CAS No. 1065193-59-0. Molecular formula: C18H27NO3. Mole weight: 305.41. BOC Sciences 9
Acetonitrile(cyclopentadienyl)[2-(di-i-propylphosphino)-4-(t-butyl)-1-methyl-1H-imidazole]ruthenium(II) hexafluorophosphate, min. 98% [Alkene Zipper Catalyst] "Zipper" catalyst for alkene isomerization over up to 30 double bond positions. Selective isomerization over one position also possible. Depending on substrate structure, H/D exchange at accessible allylic positions can be accompanied by isomerization. Group: Ruthenium catalysts. Alternative Names: MFCD22666039; 930601-66-4; Acetonitrile(cyclopentadienyl)[2-(di-ipropylphosphino)-4-(t-butyl)-1-Me-1H-imidazole]Ru(II) PF6. CAS No. 930601-66-4. Molecular formula: C21H35F6N3P2Ru. Mole weight: 606.54g/mol. IUPACName: acetonitrile; (4-tert-butyl-1-methylimidazol-2-yl)-di(propan-2-yl)phosphane; cyclopenta-1, 3-diene; ruthenium(1+); hexafluorophosphate. Canonical SMILES: CC#N. CC(C)P(C1=NC(=CN1C)C(C)(C)C)C(C)C. C1=C[CH]C=C1. F[P-](F)(F)(F)(F)F. [Ru+]. Catalog: ACM930601664. Alfa Chemistry. 2
Compstatin Compstatinis, a 13-residue cyclic peptide, is a potent inhibitor of the complement system (IC50= 12 μM) and binds to complement component C3. Synonyms: H-Ile-Cys(1)-Val-Val-Gln-Asp-Trp-Gly-His-His-Arg-Cys(1)-Thr-NH2; L-isoleucyl-L-cysteinyl-L-valyl-L-valyl-L-glutaminyl-L-alpha-aspartyl-L-tryptophyl-glycyl-L-histidyl-L-histidyl-L-arginyl-L-cysteinyl-L-threoninamide (2->12)-disulfide; 2-[(4R, 7S, 10S, 13S, 19S, 22S, 25S, 28S, 31S, 34R)-4-[[(2S, 3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]-34-[[(2S, 3S)-2-amino-3-methylpentanoyl]amino]-25-(3-amino-3-oxopropyl)-7-[3-(diaminomethylideneamino)propyl]-10, 13-bis(1H-imidazol-5-ylmethyl)-19-(1H-indol-3-ylmethyl)-6, 9, 12, 15, 18, 21, 24, 27, 30, 33-decaoxo-28, 31-di(propan-2-yl)-1, 2-dithia-5, 8, 11, 14, 17, 20, 23, 26, 29, 32-decazacyclopentatriacont-22-yl]acetic acid. Grades: 98%. CAS No. 206645-99-0. Molecular formula: C66H99N23O17S2. Mole weight: 1550.77. BOC Sciences 8
Deoxyfrenolicin It is produced by the strain of Streptomyces roseofulvus AM-3867. Deoxyfrenolicin has the ability of anti-fungal and mycoplasma. Synonyms: 2-[(1R,3S)-9-Hydroxy-5,10-Diketo-1-Propyl-3,4-Dihydro-1H-Benzo[G]Isochromen-3-Yl]Acetic Acid. CAS No. 10023-11-7. Molecular formula: C18H18O6. Mole weight: 330.33. BOC Sciences 5
Des-Acety-Cetrorelix Des-Acety-Cetrorelix is an impurity of Cetrorelix, which is a gonadotropin-releasing hormone antagonist used in the treatment of prostate and breast cancers. Synonyms: D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Alanine amide; Cetrorelix Impurity-9; Des-Ac-Cetrorelix; 3-(2-Naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; (S)-N-((R)-1-amino-1-oxopropan-2-yl)-1-((2S,5S,8R,11S,14S,17R,20R,23R)-23-amino-20-(4-chlorobenzyl)-2-(3-((diaminomethylene)amino)propyl)-11-(4-hydroxybenzyl)-14-(hydroxymethyl)-5-isobutyl-24-(naphthalen-2-yl)-4,7,10,13,16,19,22-heptaoxo-17-(pyridin-3-ylmethyl)-8-(3-ureidopropyl)-3,6,9,12,15,18,21-heptaazatetracosanoyl)pyrrolidine-2-carboxamide; D-Alaninamide, 3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-. CAS No. 121081-09-2. Molecular formula: C68H90ClN17O13. Mole weight: 1389.02. BOC Sciences 8
FR 900098 Monosodium Salt The antibiotics Fosmidomycin and FR900098 are members of a unique class of phosphonic acid natural products that inhibit the nonmevalonate pathway for isoprenoid biosynthesis. Both are potent antibacterial and antimalarial compounds. Group: Biochemicals. Alternative Names: P-[3- (Acetylhydroxyamino) propyl]phosphonic Acid Sodium Salt. Grades: Highly Purified. CAS No. 73226-73-0. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
FR900098 sodium salt FR900098 is a derivative of fosmidomycin that displays antimalarial activity. FR900098 is an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Synonyms: (3-(Acetylhydroxyamino)propyl)-phosphonic acid, monosodium salt; BRN 2096083; P-[3-(Acetylhydroxyamino)propyl]-phosphonic acid, monosodium salt. Grades: ≥95%. CAS No. 73226-73-0. Molecular formula: C5H11NO5P·Na. Mole weight: 219.1. BOC Sciences 9
Glycine isopropyl ester hydrochloride Synonyms: Gly-OiPr HCl; Isopropyl glycinate hydrochloride; glycine i-propyl ester hydrochloride; Glycine,1-Methylethyl ester hydrochloride (1:1); Glycine isopropyl ester HCl; Gly-OiPr hydrochloride; amino acetic acid isopropyl ester hydrochloride. Grades: ≥ 98% (HPLC). CAS No. 14019-62-6. Molecular formula: C5H11NO2·HCl. Mole weight: 153.64. BOC Sciences 5
Iloperidone N-Oxide an impurity in the synthesis of Iloperidone. Synonyms: 1-(3-(4-Acetyl-2-methoxyphenoxy)propyl)-4-(6-fluorobenzo[d]isoxazol-3-yl) piperidine 1-oxide. Grades: > 95%. CAS No. 1375651-09-4. Molecular formula: C24H27FN2O5. Mole weight: 442.49. BOC Sciences 7
Iopromide Impurity F Synonyms: N-(2,3-Dihydroxy-propyl)-N'-(2-hydroxymethyl-2-methyl-[1,3]dioxolan-4-ylmethyl)-2,4,6-triiodo-5-(2-methoxy-acetylamino)-N'-methyl-isophthalamide. Grades: > 95%. CAS No. 154361-54-3. Molecular formula: C21H28I3N3O9. Mole weight: 847.19. BOC Sciences 6
Iopromide Impurity G Synonyms: N-(2-Chloro-3-hydroxy-propyl)-N'-(2,3-dihydroxy-propyl)-2,4,6-triiodo-5-(2-methoxy-acetylamino)-N'-methyl-isophthalamide. Grades: > 95%. CAS No. 154361-53-2. Molecular formula: C18H23I3N3O7. Mole weight: 809.57. BOC Sciences 6
Iopromide Impurity H Synonyms: N-(2,3-Dihydroxy-propyl)-2,4,6-triiodo-5-(2-methoxy-acetylamino)-isophthalamic acid. Grades: > 95%. CAS No. 185459-57-8. Molecular formula: C14H15I3N2O7. Mole weight: 704.00. BOC Sciences 6
Isopenillic Acid Isopenillic Acid is found when penicillin G is used for the treatment of citrus greening infected trees. Synonyms: (αS)-4-Carboxy-α-(1-mercapto-1-methylethyl)-2-(phenylmethyl)-1H-imidazole-1-acetic Acid; 2-benzyl-1-((S)-1-carboxy-2-mercapto-2-methyl-propyl)-1H-imidazole-4-carboxylic acid; Benzylpenicillin Impurity 16; 1H-Imidazole-1-acetic acid, 4-carboxy-α-(1-mercapto-1-methylethyl)-2-(phenylmethyl)-, (αS)-; 2-Benzyl-1-[(1S)-1-carboxy-2-methyl-2-sulfanylpropyl]-1H-imidazole-4-carboxylic acid. Grades: 95% by HPLC. CAS No. 90962-63-3. Molecular formula: C16H18N2O4S. Mole weight: 334.39. BOC Sciences 8
Kapurimycin A1 It is originally isolated from Str. sp. DO-15. Kapurimycin A1 can resist gram-positive bacteria and a few gram-negative bacteria. Synonyms: [8-(Acetyloxy)-12-hydroxy-2-(2-methyl-3-propyloxiran-2-yl)-4,11-dioxo-8,9,10,11-tetrahydro-4H-anthra[1,2-b]pyran-5-yl]acetic acid. CAS No. 132412-65-8. Molecular formula: C27H26O9. Mole weight: 494.49. BOC Sciences 5
L-Ala(10)-Cetrorelix L-Ala(10)-Cetrorelix is an impurity of Cetrorelix, which is a gonadotropin-releasing hormone antagonist used in the treatment of prostate and breast cancers. Synonyms: Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-Ala-NH2; (S)-N-((S)-1-amino-1-oxopropan-2-yl)-1-((2S,5S,8R,11S,14S,17R,20R,23R)-20-(4-chlorobenzyl)-2-(3-((diaminomethylene)amino)propyl)-11-(4-hydroxybenzyl)-14-(hydroxymethyl)-5-isobutyl-23-(naphthalen-2-ylmethyl)-4,7,10,13,16,19,22,25-octaoxo-17-(pyridin-3-ylmethyl)-8-(3-ureidopropyl)-3,6,9,12,15,18,21,24-octaazahexacosanoyl)pyrrolidine-2-carboxamide; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-L-alaninamide. CAS No. 2886712-13-4. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06. BOC Sciences 8
Mivacurium Mivacurium is a bisbenzylisoquinolinium based and a short-duration non-depolarizing neuromuscular-blocking drug or skeletal muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, which results in a block of neuromuscular transmission. It is used in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during mechanical ventilation or surgery. Uses: Mivacurium is a short-duration non-depolarizing neuromuscular-blocking drug or skeletal muscle relaxant. Synonyms: 2, 2'-[ (1, 8-Dioxo-4-octene-1, 8-diyl) bis (oxy-3, 1-propanediyl) ]bis[1, 2, 3, 4-tetrahydro-6, 7-dimethoxy-2-methyl-1-[ (3, 4, 5-trimethoxyphenyl) methyl]isoquinolinium; Isoquinolinium, 2,2'-((1,8-dioxo-4-octene-1,8-diyl)bis(oxy-3,1-propanediyl))bis(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-((3,4,5-trimethoxyphenyl)methyl)-;Bis[3-[(1R)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (E)-oct-4-enedioate;BW-B-1090U;Mivacron;(1R,1'R)-2,2'-((((E)-oct-4-enedioyl)bis(oxy))bis(propane-3,1-diyl))bis(6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium). Grades: 95%. CAS No. 106791-40-6. Molecular formula: C58H80N2O14. Mole weight: 1029.28. BOC Sciences 9
Montelukast R, R-Isomer An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 2- (1- ( ( ( (R) -1- (3- ( (R) -1- ( ( (1- (carboxymethyl) cyclopropyl) methyl) thio) -2- (7-chloroquinolin-2-yl) ethyl) phenyl) -3- (2- (2-hydroxypropan-2-yl) phenyl) propyl) thio) methyl) cyclopropyl) acetic acid. Grades: > 95%. Molecular formula: C41H46ClNO5S2. Mole weight: 732.41. BOC Sciences 6
N-Cyclohexylsulphamic acid,compound with alpha-[2- (dimethylamino)propyl]-alpha-isopropylbenzene-1-acetonitrile (1: 1) Heterocyclic Organic Compound. Alternative Names: N-cyclohexylsulphamic acid, compound with alpha-[2- (dimethylamino)propyl]-alpha-isopropylbenzene-1-acetonitrile (1:1);Isoaminile cyclamate. CAS No. 10075-36-2. Molecular formula: C16H24N2.C6H13NO3S. Mole weight: 423.618. Catalog: ACM10075362. Alfa Chemistry. 3
Propranolol N-Acetyl Impurity An impurity of Propranolol.Propranolol is Beta 1 adrenergic receptor antagonist. It can be used for the treatment of high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors. Synonyms: N-Acetylpropranolol; 2007-11-6; Propranolol N-Acetyl Impurity; AW44QKZ2SH; N-(2-hydroxy-3-(naphthalen-1-yloxy)propyl)-n-isopropylacetamide; N-(2-hydroxy-3-naphthalen-1-yloxypropyl)-N-propan-2-ylacetamide; Acetamide, N-(2-hydroxy-3-(1-naphthalenyloxy)propyl)-N-(1-methylethyl)-; UNII-AW44QKZ2SH; SCHEMBL9330158; DTXSID40942091; F19345; N-{2-Hydroxy-3-[(naphthalen-1-yl)oxy]propyl}-N-(propan-2-yl)acetamide. Grades: > 95%. CAS No. 2007-11-6. Molecular formula: C18H23NO3. Mole weight: 301.39. BOC Sciences 7
rac D 617 (verapamil metabolite) A metabolite of Verapamil. Group: Biochemicals. Alternative Names: 3, 4-Dimethoxy-α -[3- (methylamino) propyl]-α - (1-methylethyl) benzeneacetonitrile; 1-Isopropyl-1-N-methylpropylamino- (3, 4-dimethoxyphenyl) acetonitrile; 2- (3, 4-Dimethoxyphenyl) -2-isopropyl-5- (methylamino) valeronitrile; N-Methyl-4-(3,4-dimethoxyphenyl)-4-cyano-5-methylhexylamine. Grades: Highly Purified. CAS No. 34245-14-2. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 290.4. US Biological Life Sciences. USBiological 1
Worldwide
Rifalazil Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase. Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml. Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia?infection, Clostridium difficile?associated diarrhea (CDAD), and tuberculosis (TB). Group: Inhibitors. Alternative Names: RIFALAZIL;KRM 1648; 3-Hydroxy-5- (4-isobutylpiperazinyl) benzoxazinorifamycin; 5, 12-Dihydroxy-2, 4-dimethyl-10-[4- (2-methyl-propyl) -l-piperazinyl]-2, 7-[oxy (5-acetoxy-7, 9-dihydroxy-3-methoxy-4, 6, 8, 10, 14-pentamethyl-15-oxo-l, ll, 13-pentadecatriene-l, 15-diyl) imino]-6H-benzofuro[4, 5-a]phenoxazine-l (2H) , 6-dione; 1-Deoxy-1-dehydro-1-oxo-3-hydroxy-5-[4- (2-methylpropyl) piperazino]rifamycin VIII. CAS No. 129791-92-0. Molecular formula: C51H64N4O13. Mole weight: 941.07. Appearance: Solid. Purity: 0.9806. Canonical SMILES: CC (C)CN (CC1)CCN1C2=CC (O3)=C (C (O)=C2)N=C (C3=C (NC (/C (C)=C\C=C\[C@@H] ([C@H] (O)[C@@H] (C)[C@@H] (O)[C@@H] (C)[C@@H] ([C@@H] ([C@H] (/C=C/O[C@@]4 (C)O5)OC)C)OC (C)=O)C)=O)C6=O)C7=C6C (O)=C (C)C5=C7C4=O. Catalog: ACM129791920. Alfa Chemistry.
(S)-Ranolazine (S)-Ranolazine is the S-isomer of Ranolazine, which is a medication used to treat heart-related chest pain. Synonyms: 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[(2S)-2-hydroxy-3-(2-methoxyphenoxy)propyl]-; N-(2,6-Dimethylphenyl)-2-{4-[(2S)-2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazinyl}acetamide; (-)-Ranolazine. Grades: ≥95%. CAS No. 114246-81-0. Molecular formula: C24H33N3O4. Mole weight: 427.54. BOC Sciences 8
TAK-448 TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin. In animal model, TAK-448 can stimulate LH/FSH release, whereas continuous sc exposure rapidly down-regulates the pituitary-gonadal axis, with rapid reduction of T levels in a dose-dependent manner. Phase II clinical trials for the treatment of Prostate cancer was discontinued. In Dec 2016, Takeda terminated a phase II trial in Hypogonadism (In adults, In the elderly) in USA because the study did not meet the primary endpoints. Uses: Hypogonadism;prostate cancer. Synonyms: MVT-602; Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2; RVT-602; RVT 602; TAK 448; RVT602; TAK448; N-acetyl-D-tyrosyl-(4R)-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl-2-azaglycyl-L-leucyl-N5-(imino(methylamino)methyl)-L-ornithyl-L-Tryptophanamide; Istaroxime; (2S,5S,8S,14S,17S,20S)-20-[({(2S,4R)-1-[(2R)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxy-2-pyrrolidinyl}carbonyl)amino]-14-benzyl-17-(1-hydroxyethyl)-2-(1H-indol-3-ylmethyl)-8-isobutyl-5-[3-(N'-methylcarbamimidamido)propyl]-4,7,10,13,16,19-hexaoxo-3,6,9,11,12,15,18-heptaazadocosane-1,22-diamide. Grades: 98%. CAS No. 1234319-68-6. Molecular formula: C58H80N16O14. Mole weight: 1225.36. BOC Sciences 8
Verapamil Impurity F Verapamil Impurity F is a metabolite of Verapamil. Verapamil is a medication used for the treatment of high blood pressure, chest pain from not enough blood flow to the heart, and supraventricular tachycardia. Synonyms: rac D 617; 3,4-Dimethoxy-α-[3-(methylamino)propyl]-α-(1-methylethyl)benzeneacetonitrile; 1-Isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile; 2-(3,4-Dimethoxyphenyl)-2-isopropyl-5-(methylamino)valeronitrile; N-Methyl-4-(3,4-dimethoxyphenyl)-4-cyano-5-methylhexylamine. CAS No. 34245-14-2. Molecular formula: C17H26N2O2. Mole weight: 290.41. BOC Sciences 7

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