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Isoflavone. Group: Biochemicals. Grades: Highly Purified. CAS No. 574-12-9. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C15H10O2. US Biological Life Sciences.
Worldwide
Isoflavone
Isoflavone is an orally available bioactive component of soy phytoestrogen with lipid-lowering and antioxidant activities. Isoflavone prevents a variety of chronic diseases by regulating fatty acid oxidation in the liver and gene expression in adipose tissue. In addition, isoflavone has important value in the research of cancer and cardiovascular diseases [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 574-12-9. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg. Product ID: HY-W006405.
isoflavone 2'-hydroxylase
A heme-thiolate protein (P-450). Acts on daidzein, formononetin and genistein. EC 1.14.13.53, 4'-methoxyisoflavone 2'-hydroxylase, has the same reaction but is more specific as it requires a 4'-methoxyisoflavone. Group: Enzymes. Synonyms: isoflavone 2'-monooxygenase; CYP81E1; CYP Ge-3. Enzyme Commission Number: EC 1.14.13.89. CAS No. 110183-49-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0897; isoflavone 2'-hydroxylase; EC 1.14.13.89; 110183-49-8; isoflavone 2'-monooxygenase; CYP81E1; CYP Ge-3. Cat No: EXWM-0897.
isoflavone 3'-hydroxylase
A heme-thiolate protein (P-450). Also acts on biochanin A and other isoflavones with a 4'-methoxy group. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. Group: Enzymes. Synonyms: isoflavone 3'-monooxygenase. Enzyme Commission Number: EC 1.14.13.52. CAS No. 110183-50-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0859; isoflavone 3'-hydroxylase; EC 1.14.13.52; 110183-50-1; isoflavone 3'-monooxygenase. Cat No: EXWM-0859.
isoflavone 4'-O-methyltransferase
Requires Mg2+ for activity. The enzyme catalyses the methylation of daidzein and genistein. It does not methylate naringenin, apigenin, luteolin or kaempferol. Group: Enzymes. Synonyms: 4'-hydroxyisoflavone methyltransferase; isoflavone methyltransferase; isoflavone O-methyltransferase. Enzyme Commission Number: EC 2.1.1.46. CAS No. 55071-80-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1950; isoflavone 4'-O-methyltransferase; EC 2.1.1.46; 55071-80-2; 4'-hydroxyisoflavone methyltransferase; isoflavone methyltransferase; isoflavone O-methyltransferase. Cat No: EXWM-1950.
The 6-position of the glucose residue of formononetin can also act as acceptor; some other 7-O-glucosides of isoflavones, flavones and flavonols can also act, but more slowly. Group: Enzymes. Synonyms: flavone/flavonol 7-O-β-D-glucoside malonyltransferase; flavone (flavonol) 7-O-glycoside malonyltransferase; malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase; MAT-7; malonyl-coenzyme A:isoflavone 7-O-glucoside-6''-malonyltransferase; malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase. Enzyme Commission Number: EC 2.3.1.115. CAS No. 93585-97-8, 78413-09-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2054; isoflavone-7-O-β-glucoside 6''-O-malonyltransferase; EC 2.3.1.115; 93585-97-8, 78413-09-9; flavone/flavonol 7-O-β-D-glucoside malonyltransferase; flavone (flavonol) 7-O-glycoside malonyltransferase; malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase; MAT-7; malonyl-coenzyme A:isoflavone 7-O-glucoside-6''-malonyltransferase; malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase. Cat No: EXWM-2054.
isoflavone 7-O-glucosyltransferase
The 4'-methoxy isoflavones biochanin A and formononetin and, more slowly, the 4'-hydroxyisoflavones genistein and daidzein, can act as acceptors. The enzyme does not act on isoflavanones, flavones, flavanones, flavanols or coumarins. Group: Enzymes. Synonyms: uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase; UDPglucose-favonoid 7-O-glucosyltransferase; UDPglucose:isoflavone 7-O-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.170. CAS No. 97089-62-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2395; isoflavone 7-O-glucosyltransferase; EC 2.4.1.170; 97089-62-8; uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase; UDPglucose-favonoid 7-O-glucosyltransferase; UDPglucose:isoflavone 7-O-glucosyltransferase. Cat No: EXWM-2395.
isoflavone 7-O-methyltransferase
The enzyme from alfalfa can methylate daidzein, genistein and 6,7,4'-trihydroxyisoflavone but not flavones or flavanones. Group: Enzymes. Enzyme Commission Number: EC 2.1.1.150. CAS No. 136111-54-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1746; isoflavone 7-O-methyltransferase; EC 2.1.1.150; 136111-54-1. Cat No: EXWM-1746.
2'-hydroxyisoflavone reductase
In the reverse reaction, a 2'-hydroxyisoflavone is reduced to an isoflavanone; 2'-hydroxypseudobaptigenin also acts. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. Group: Enzymes. Synonyms: NADPH:2'-hydroxyisoflavone oxidoreductase; isoflavone reductase; 2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase. Enzyme Commission Number: EC 1.3.1.45. CAS No. 128449-69-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1317; 2'-hydroxyisoflavone reductase; EC 1.3.1.45; 128449-69-4; NADPH:2'-hydroxyisoflavone oxidoreductase; isoflavone reductase; 2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase. Cat No: EXWM-1317.
4',6,7-Trihydroxyisoflavone
4',6,7-Trihydroxyisoflavone is an isoflavone isolated from the seeds of Glycine max with antioxidant activity. It is also a novel inhibitor of PKCα that suppresses solar UV-induced matrix metalloproteinase 1. Synonyms: Demethyltexasin; 6,7,4'-trihydroxyisoflavone; 6-Hydroxydaidzein; 6,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one. Grades: >98%. CAS No. 17817-31-1. Molecular formula: C15H10O5. Mole weight: 270.24.
4'-methoxyisoflavone 2'-hydroxylase
A heme-thiolate protein (P-450). Acts on isoflavones with a 4'-methoxy group, such as formononetin and biochanin A. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. EC 1.14.13.89, isoflavone 2'-hydroxylase, is less specific and acts on other isoflavones as well as 4'-methoxyisoflavones. Group: Enzymes. Synonyms: isoflavone 2'-monooxygenase (ambiguous); isoflavone 2'-hydroxylase (ambiguous). Enzyme Commission Number: EC 1.14.13.53. CAS No. 110183-49-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0860; 4'-methoxyisoflavone 2'-hydroxylase; EC 1.14.13.53; 110183-49-8; isoflavone 2'-monooxygenase (ambiguous); isoflavone 2'-hydroxylase (ambiguous). Cat No: EXWM-0860.
7-Hydroxyisoflavone
7-Hydroxyisoflavone (compound 3) is a natural isoflavone compound [1]. Uses: Scientific research. Group: Natural products. CAS No. 13057-72-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-W031126.
7-Methoxyisoflavone
7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase ( AMPK ). Uses: Scientific research. Group: Signaling pathways. CAS No. 1621-56-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N6631.
Biochanin A (5,7-Dihydroxy-4-methoxyisoflavone)
An isoflavone with anticancer proliferation, differentiation and chemopreventitive properties. Inhibits metabolic activation of benzo[a]pyrene. Group: Biochemicals. Alternative Names: 5,7-Dihydroxy-4-methoxyisoflavone. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Isoflavone derivative found in soy-based food products. Group: Biochemicals. Grades: Highly Purified. CAS No. 40957-83-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
monoprenyl isoflavone epoxidase
A flavoprotein (FAD) with high specificity for monoprenyl isoflavone. The product of the prenyl epoxidation reaction contains an oxygen atom derived from O2, but not from H2O. It is slowly and non-enzymically converted into the corresponding dihydrofurano derivative. The enzyme in the fungus Botrytis cinerea is induced by the substrate analogue, 6-prenylnaringenin. Group: Enzymes. Synonyms: monoprenyl isoflavone monooxygenase; 7-O-methylluteone:O2 oxidoreductase; 7-O-methylluteone,NADPH:O2 oxidoreductase. Enzyme Commission Number: EC 1.14.99.34. CAS No. 198496-86-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1046; monoprenyl isoflavone epoxidase; EC 1.14.99.34; 198496-86-5; monoprenyl isoflavone monooxygenase; 7-O-methylluteone:O2 oxidoreductase; 7-O-methylluteone,NADPH:O2 oxidoreductase. Cat No: EXWM-1046.
Specifically methylates 2,4',7-trihydroxyisoflavanone on the 4'-position. No activity with isoflavones. The enzyme is involved in formononetin biosynthesis in legumes. The protein from pea (Pisum sativum) also methylates (+)-6a-hydroxymaackiain at the 3-position (cf. EC 2.1.1.270, (+)-6a-hydroxymaackiain 3-O-methyltransferase). Group: Enzymes. Synonyms: SAM:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; HI4'OMT; HMM1; MtIOMT5; S-adenosyl-L-methionine:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase. Enzyme Commission Number: EC 2.1.1.212. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1814; 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; EC 2.1.1.212; SAM:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; HI4'OMT; HMM1; MtIOMT5; S-adenosyl-L-methionine:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase. Cat No: EXWM-1814.
2'-hydroxydaidzein reductase
In the reverse reaction, the 2'-hydroxyisoflavone (2'-hydroxydaidzein) is reduced to an isoflavanone. Also acts on 2'-hydroxyformononetin and to a small extent on 2'-hydroxygenistein. Involved in the biosynthesis of the phytoalexin glyceollin. The isoflavones biochanin A, daidzein and genestein as well as the flavonoids apigenin, kaempferol and quercetin do not act as substrates. Group: Enzymes. Synonyms: NADPH:2'-hydroxydaidzein oxidoreductase; HDR; 2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase. Enzyme Commission Number: EC 1.3.1.51. CAS No. 126125-01-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1323; 2'-hydroxydaidzein reductase; EC 1.3.1.51; 126125-01-7; NADPH:2'-hydroxydaidzein oxidoreductase; HDR; 2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase. Cat No: EXWM-1323.
3-(4-Hydroxyphenyl)chroman-7-yl Hexanoate
3-(4-Hydroxyphenyl)chroman-7-yl Hexanoate is an intermediate in the synthesis of glucuronide metabolites of isoflavone Daidzein (D103500). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C21H24O4. US Biological Life Sciences.
3- (4- ( (tert-Butyldimethylsilyl) oxy) phenyl) chroman-7-ol is an protected intermediate in the synthesis of isoflavone Daidzein (D103500) related compounds. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C21H28O3Si, Molecular Weight: 356.53. US Biological Life Sciences.
Worldwide
3'-Methoxydaidzein
3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC 50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels [1]. Uses: Scientific research. Group: Natural products. CAS No. 21913-98-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N1847.
3-Methoxyphenyl acetonitri le
3-Methoxyphenyl acetonitri le is used in the synthesis of isoflavones which inhibit epithelial cell proliferation and induce apoptosis in vitro. Group: Biochemicals. Alternative Names: 3-Methoxy Benzene acetonitrile; (m-Methoxyphenyl) acetonitrile; (3-Methoxyphenyl) acetonitrile; (m-Methoxyphenyl) acetonitrile; 2- (3-Methoxyphenyl) acetonitrile; 3-Methoxy Benzene acetonitrile; 3-Methoxybenzyl Cyanide; Limnanthin Nitrile; NSC 143401; m-Methoxybenzyl Cyanide. Grades: Highly Purified. CAS No. 19924-43-7. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
3'-Methoxypuerarin
3'-Methoxypuerarin (3'-MOP) is an isoflavone extracted from radix puerariae that shows neuron protection activity. Uses: Scientific research. Group: Natural products. CAS No. 117047-07-1. Pack Sizes: 5 mg. Product ID: HY-N1978.
6''-O-Acetylglycitin
6''-O-Acetylglycitin, a acetyl glucoside, is one of the isoflavone isomer in soybeans, shows various extents of content reduction dependent on storage temperature, packaging condition, and its isoflavone isomer kind [1]. Uses: Scientific research. Group: Natural products. CAS No. 134859-96-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N4072.
6''-O-Malonylgenistin
6''-O-Malonylgenistin (Malonylgenistin) is an isoflavone derivative. Uses: A derivative of genistin. inhibitor. Synonyms: Malonylgenistin Genistin 6-O-malonate. Grades: ≥95%. CAS No. 51011-05-3. Molecular formula: C24H22O13. Mole weight: 518.42.
Afromosin
Afromosin is an isoflavone, that can be isolated from Millettia dielsiana Harms. Afromosin exhibits remarkable tumor inhibitory effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 550-79-8. Pack Sizes: 1 mg. Product ID: HY-119846.
Biochanin A b-D-glucuronide
Biochanin A b-D-glucuronide is an esteemed compound, acting as a glucuronide conjugate of Biochanin A, an innate isoflavone sourced from botanical entities. Embracing an antioxidative nature, Biochanin A b-D-glucuronide reigns supreme for its anti-mutagenic as well as estrogenic attributes. Synonyms: Biochanin a 7-glucuronide; 38482-76-7; Biochanin A-7-O-beta-D-glucuronide; (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-3-(4-methoxyphenyl)-4-oxochromen-7-yl]oxyoxane-2-carboxylic acid; Biochanin A beta-D-glucuronide; CHEBI:189737; MFCD31811654; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-((5-hydroxy-3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid. CAS No. 38482-76-7. Molecular formula: C22H20O11. Mole weight: 460.39.
biochanin-A reductase
Some other isoflavones are reduced to the corresponding isoflavanones. Group: Enzymes. Enzyme Commission Number: EC 1.3.1.46. CAS No. 112198-90-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1318; biochanin-A reductase; EC 1.3.1.46; 112198-90-0. Cat No: EXWM-1318.
Daidzein
Daidzein is a soy isoflavone, which acts as a PPAR activator. Uses: Scientific research. Group: Natural products. CAS No. 486-66-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N0019.
Daidzein Diacetate
Protected Daidzein. Group: Biochemicals. Alternative Names: 7-(Acetyloxy)-3-[4-(acetyloxy)phenyl]-4H-1-benzopyran-4-one; 4',7-Dihydroxy-isoflavone Diacetate; 4',7-Diacetyl-O-isoflavone; 7,4'-Diacetoxyisoflavone. Grades: Highly Purified. CAS No. 3682-1-7. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
Daidzein (Standard)
Daidzein (Standard) is the analytical standard of Daidzein. This product is intended for research and analytical applications. Daidzein is a soy isoflavone, which acts as a PPAR activator. Uses: Scientific research. Group: Natural products. CAS No. 486-66-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N0019R.
Daidzin
Daidzin is an isoflavone that has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities; directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic isoflavone. Group: Inhibitors. Alternative Names: Daidzoside. CAS No. 552-66-9. Molecular formula: C21H20O9. Mole weight: 416.38. Appearance: Solid. Purity: 0.9977. Canonical SMILES: OC1=CC=C (C2=COC (C=C (O[C@H]3[C@H] (O)[C@@H] (O)[C@H] (O)[C@@H] (CO)O3)C=C4)=C4C2=O)C=C1. Catalog: ACM552669.
Daidzin
Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Daidzoside; NPI-031D; Daidzein 7-O-glucoside. CAS No. 552-66-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-N0018.
Derrone
Derrone, a prenylated isoflavones, is an Aurora kinase inhibitor, with IC50 values of 6 and 22.3 μM against Aurora B and Aurora A, respectively. Derrone shows anti-tumor activity. Group: Inhibitors. CAS No. 76166-59-1. Molecular formula: C20H16O5. Mole weight: 336.34. Canonical SMILES: O=C1C2=C (O)C=C3C (C=CC (C) (C)O3)=C2OC=C1C4=CC=C (O)C=C4. Catalog: ACM76166591.
Derrubone
Derrubone is a prenylated isoflavone, a type of flavonoid. It was originally isolated from the Indian tree Derris robusta.It has potential application as an inhibitor of Hsp90 to its function as a chaperone protein. Synonyms: 5,7-Dihydroxy-3',4'-methylenedioxy-6-prenylisoflavone. Grades: >98%. CAS No. 22044-58-2. Molecular formula: C21H18O6. Mole weight: 366.37.
Dichotomitin
Dichotomitin is an isoflavonoid isolated from the rhizomes of Belamcanda chinensis (L.) DC. Synonyms: 9-hydroxy-7-(3-hydroxy-4,5-dimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromen-8-one; 5,3'-Dihydroxy-4',5'-dimethoxy-6,7-methylenedioxyisoflavone; 8H-1,3-Dioxolo(4,5-g)(1)benzopyran-8-one, 9-hydroxy-7-(3-hydroxy-4,5-dimethoxyphenyl)-. Grades: >98%. CAS No. 88509-91-5. Molecular formula: C18H14O8. Mole weight: 358.3.
(±)-Equol
(±)-Equol is the racemate of equol. (±)-equol exhibits EC 50 s of 200 and 74 nM for human ERα and ERβ, respectively. Equol is a metabolite of the soy isoflavones, daidzin and daidzein. Uses: Scientific research. Group: Natural products. CAS No. 94105-90-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100583A.
Formononetin
Formononetin is an isoflavone found as one of the main plant estrogens in animal feed. When metabolized in the rumen this compound transforms into a potent estrogen. Group: Biochemicals. Alternative Names: 7-Hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one; 7-Hydroxy-4'-methoxy- isoflavone; 7-Hydroxy-3-(4-methoxyphenyl)chromen-4-one; 7-Hydroxy-4'-methoxyisoflavone; Biochanin B; Daidzein 4'-methyl ether; Flavosil; Formonentin; Formonetin; Formononetol; Myconate; NSC 93360. Grades: Highly Purified. CAS No. 485-72-3. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Formononetin-b-D-glucuronide sodium salt
Formononetin-b-D-glucuronide sodium salt is a bioactive derivative originating from formononetin is an isoflavone occurring naturally in numerous plant species. It is used in the research of osteoporosand estrogen-related disorders. Synonyms: 3-(4-Methoxyphenyl)-4-oxo-4H-1-benzopyran-7-yl b-D-glucuronic acid; 7-Hydroxy-4-methoxyisoflavone-7-O-b-D-glucuronide; Formononetin-7-O-Glucuronide; Biochanin B-7-O-b-D-glucuronide. CAS No. 18524-03-3. Molecular formula: C22H19O10Na. Mole weight: 466.37.
Genistein
Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR ) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis , the cell cycle, and angiogenesis and inhibiting metastasis. Uses: Scientific research. Group: Natural products. Alternative Names: NPI 031L. CAS No. 446-72-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14596.
A derivative of Genistein. Inhibitor. Isoflavone derivative found in soy-based food products. Group: Biochemicals. Alternative Names: Genistein 7-O-Glucoside; Genistein-7-b-O-Glucopyranoside;7-(b-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Genistoside; NSC 5112. Grades: Highly Purified. CAS No. 529-59-9. Pack Sizes: 25mg, 100mg. US Biological Life Sciences.
Worldwide
Genistin
Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Genistine; Genistoside; Genistein 7-O-β-D-glucopyranoside. CAS No. 529-59-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0595.
Glucoerysodine
Glucoerysodine is a pentacyclic triterpene with anticancer activity. It has been shown to have a cytotoxic effect on fibroblast cells, which may be due to its ability to inhibit the synthesis of acetylcholinesterase. Glucoerysodine is also able to suppress the growth of animal tumors and induce apoptosis in cancer cells. The molecular docking analysis of glucoerysodine with the human estrogen receptor alpha (ERα) indicates that it binds to ERα and blocks its transcriptional activity. This drug also contains isoflavones, which are plant-derived compounds that have been shown to inhibit tumor cell proliferation in vitro and in vivo, as well as inhibit DNA methylation. Group: Other alkaloids. CAS No. 509-49-9. Molecular formula: C24H31NO8. Mole weight: 461.5 g/mol. Catalog: ACM509499.
Glycine Soja (Soybean) Germ Extract
Glycine Soja (Soybean) Germ Extract is a natural extract derived from the germ of soybeans. Soybean germ is the part of the soybean that sprouts and grows into a new plant. This extract is rich in nutrients like vitamins, minerals, and antioxidants. It also contains phytochemicals such as isoflavones, which are known to have anti-inflammatory and antioxidant properties. In skincare products, Glycine Soja (Soybean) Germ Extract is often used for its moisturizing properties. It is also believed to help protect the skin against environmental stressors like pollution and UV radiation. Some studies have suggested that isoflavones in soybean germ extract may have anti-aging effects and improve skin elasticity. Uses: 1. anti-inflammatory: glycine soja germ extract has potent anti-inflammatory properties, which makes it beneficial in managing skin conditions associated with inflammation, such as eczema. 2. anti-aging: studies have shown that glycine soja germ extract can reduce the appearance of fine lines and wrinkles, making it an effective ingredient in anti-aging skincare products. 3. moisturizing: glycine. Group: Hair actives. CAS No. 84776-91-0. Appearance: pale-yellow to brownish colored liquid or powder. Catalog: CI-HC-0235.
Glycitein
Glycitein is a soybean (yellow cultivar) isoflavonoid. It may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Uses: The compund shows an anti-cancer activity. Synonyms: 7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-; 7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4-chromenone; 4',7-Dihydroxy-6-methoxyisoflavone. Grades: >98%. CAS No. 40957-83-3. Molecular formula: C16H12O5. Mole weight: 284.26.
Glycitein
Glycitein is a soy isoflavone used to study apoptosis and antioxidant [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Glycetein. CAS No. 40957-83-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0016.
Glycitin
Glycitin (Glycitein 7-O-β-glucoside) is a natural isoflavone with antibacterial, antiviral, anticancer, anti-inflammation, anti-aging and estrogenic effects. Glycitin may regulate osteoblasts through TGF-β or AKT signaling pathways in bone marrow stem cells (BMSCs) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Glycitein 7-O-β-glucoside. CAS No. 40246-10-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0012.
Glycitin
Glycitin is a natural isoflavone isolated from legumes; promotes the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover.Glycitin is antibacterial, antiviral and estrogenic. Group: Inhibitors. CAS No. 40246-10-4. Molecular formula: C22H22O10. Mole weight: 446.4. Appearance: Solid. Purity: 0.9984. Canonical SMILES: O[C@H]1[C@H] (O)[C@@H] (CO)O[C@@H] (OC2=CC (OC=C (C3=CC=C (O)C=C3)C4=O)=C4C=C2OC)[C@@H]1O. Catalog: ACM40246104.
Isoflavone derivative found in soy-based food products. Group: Biochemicals. Grades: Highly Purified. CAS No. 40246-10-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ipriflavone
Ipriflavone is a synthetic isoflavone derivative used to suppress bone resorption. Uses: Scientific research. Group: Signaling pathways. CAS No. 35212-22-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0094.
Iridin
Iridin is an isoflavone isolated from Iris milesii [1]. Uses: Scientific research. Group: Natural products. CAS No. 491-74-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N3011.
Irigenin
Irigenin is identified as an α-glucosidase inhibitors. Also, it is a lead compound to overcome Fibronectin EDA induced metastatic progression in lung carcinoma cells. Group: Biochemicals. Alternative Names: 3',5,7-Trihydroxy-4',5',6-trimethoxy-isoflavone; 5,7-Dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 548-76-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C??H??O?, Molecular Weight: 360.31. US Biological Life Sciences.
Worldwide
Irisflorentin
Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 41743-73-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0268.
kaempferol 4'-O-methyltransferase
The enzyme acts on the hydroxy group in the 4'-position of some flavones, flavanones and isoflavones. Kaempferol, apigenin and kaempferol triglucoside are substrates, as is genistein, which reacts more slowly. Compounds with an hydroxy group in the 3' and 4' positions, such as quercetin and eriodictyol, do not act as substrates. Similar to EC 2.1.1.75, apigenin 4'-O-methyltransferase and EC 2.1.1.83, 3,7-dimethylquercetin 4'-O-methyltransferase. Group: Enzymes. Synonyms: S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase; F 4'-OMT. Enzyme Commission Number: EC 2.1.1.155. CAS No. 80747-20-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1751; kaempferol 4'-O-methyltransferase; EC 2.1.1.155; 80747-20-2; S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase; F 4'-OMT. Cat No: EXWM-1751.
Kudzu Root Extract (Standard)
Kudzu root has been known for centuries in traditional Chinese medicine as ge-gen. The first written mention of the plant as a medicine is in the ancient herbal text of Shen Nong (about A.D.100). In traditional Chinese medicine, kudzu root is used in prescriptions for the treatment of thirst, headache, and stiff neck with pain due to high blood pressure. It is also recommended for allergies, migraine headaches, inadequate measles eruptions in children, and diarrhea It is also used in modern Chinese medicine as a treatment for angina pectoris. Applications: Kudzu root extract is used as remedy for diaphoretic,antispasmodic,muscle relaxant,antipyretic.kudzu root extract is also used for fevers caused by heat in colds and influenza and for stiff neck and shoulders. Group: Others. CAS No. Puerarin: 3681-99-0Genistein: 446-72-0Daidzin: 552-66-9Daidzein: 486-66-8. Purity: 40.0% Isoflavones UV/HPLC. Mole weight: Puerarin: 416.37Genistein: 270.23Daidzin: 416.38Daidzein: 254.23. Kudzu Root Extract (Standard); Puerarin: 3681-99-0Genistein: 446-72-0Daidzin: 552-66-9Daidzein: 486-66-8; Puerarin: C21H20O9Genistein: C15H10O5Daidzin: C21H20O9Daidzein: C10H15O4. Cat No: EXTW-008.
NV-128
NV-128 is a novel isoflavone derivative, which has been shown in pre-clinical studies to promote cancer cell death in multi drug resistant cancer cells by inducing caspase-independent DNA degradation and cancer cell death via the AKT-mTOR pathway. In contrast to phenoxodiol and triphendiol, NV-128 has been shown to induce caspase-independent DNA degradation and cancer cell death. It appears that in conjunction with autophagy induction, NV-128 induces caspase independent cell death via the AKT-mTOR pathway resulting in beclin sequestration of Bcl-2, Bax up-regulation and mitochondrial depolarization. As a consequence, endonuclease G translocates to the nucleus where it initiates DNA degradation and cell death. This offers an opportunity for use as a monotherapy in chemoresistant cancers and enhanced efficacy against cancer targets less susceptible to phenoxodiol. The option for co-administration of combinations of these drugs is also under investigation to extend the potential therapeutic range of this unique class of oncology compounds. Synonyms: NV-128; NV 128; NV128. CAS No. 1210335-22-0.
O-Desmethylangolensin
O-Desmethylangolensin is a metabolite of soy isoflavone, daidzein metabolized by gut microbiota. O-Desmethylangolensin possesses antioxidant activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 21255-69-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N4075.
Ononin
Ononin is an orally active isoflavone. Ononin inhibits the ERK/JNK/p38 and PI3K/Akt/mTOR pathways. Ononin regulates Apoptosis. Ononin has anti-tumor effects on laryngeal cancer and lung cancer. Ononin has neuroprotective effects. Ononin alleviates endoplasmic reticulum stress and diabetic nephropathy [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Ononoside; Formononetin 7-O-β-D-glucopyranoside. CAS No. 486-62-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0270.
Orobol
Orobol is one of the major soy isoflavones and has various pharmacological activities, including anti-skin-aging and anti-obesity effects. Orobol inhibits CK1ε, VEGFR2, MAP4K5, MNK1, MUSK, TOPK, and TNIK (IC50=1.24-4.45 μM). Orobol also inhibits PI3K isoforms (IC50=3.46-5.27 μM for PI3K α/β/γ/K/δ). Group: Inhibitors. CAS No. 480-23-9. Molecular formula: C15H10O6. Mole weight: 286.24. Canonical SMILES: O=C1C2=C (O)C=C (O)C=C2OC=C1C3=CC (O)=C (O)C=C3. Catalog: ACM480239.
Prunetin
Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 552-59-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2597.
Puerarin
Puerarin is an isoflavone extracted from Pueraria root and is a 5-HT2C receptor antagonist. Puerarin inhibits the dorsal motor nucleus of the vagus (DMV)-vagus nerve pathway, which in turn leads to decreased fat absorption [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 3681-99-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0145.
Red Clover Extract
Red clover extract is prepared from trifolium pratense, a perennial herb that commonly grows wild in meadows throughout Europe and Asia. Red clover extract powder is considered to be one of the richest sources of isoflavones. Red clover extract Flavone is used for hot flashes/flushes, PMS, lowering cholesterol, breast enhancement and breast health, improving urine production and improving circulation of the blood. Group: Others. Red Clover Extract; Trifolium Pratente L. Cat No: EXTC-028.
R,S-Equol (4,7-Isoflavandiol)
A human urinary metabolite of Daidzein. Its als a natural estrogenic metabolite from soy isoflavones. Group: Biochemicals. Alternative Names: 4,7-Isoflavandiol. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
R,S-Equol 7-b-D-glucuronide sodium salt
R,S-Equol 7-b-D-glucuronide sodium salt is a sodium salt derivative of R,S-Equol is a soy isoflavone daidzein metabolite. It finds utility within the biomedical sector, primarily focusing on the research of hormone-dependent ailments including breast and prostate cancer. Synonyms: 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-yl-b-D-glucuronide. CAS No. 38482-82-5. Molecular formula: C21H21NaO9. Mole weight: 440.38.
(R,S)-Equol-d4 (Major). (Mixture of Diastereomers)
A deuterated human urinary metabolite of Daidzein. Equol is a natural estrogenic metabolite of soy isoflavones. Group: Biochemicals. Alternative Names: 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol-d4;4,7-Isoflavandiol-d4; (+/-)-Equol-d4; 7,4-Homoisoflavane-d4; NV 07α-d4. Grades: Highly Purified. CAS No. 1216469-13-4. Pack Sizes: 5mg. Molecular Formula: C15H10D4O3, Molecular Weight: 246.29. US Biological Life Sciences.
Worldwide
Sophoricoside
Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects. Uses: Scientific research. Group: Natural products. CAS No. 152-95-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0423.
Soybean Extract
Soybean extract is prepared from natural soy bean, which belongs to Leguminosae Family, annual herb, widely planted in China. Soybean extract contains valuable constituents, including protein, isoflavone, saponins, and phytosterols. In the case of strong estrogen physiological activity, soybean extract isoflavone can play the role of anti-estrogen. Soybean isoflavone has very prominent anti-cancer properties, can hinder the growth and spread of cancer cells and only cancer. Group: Others. Mole weight: 750. Soybean Extract; clycine max (l.) Merr. Cat No: EXTC-039.
Tectoridin
Tectoridin is a isoflavone isolated from Maackia amurensis. Tectoridin is a phytoestrogen and activates estrogen and thyroid hormone receptors. Tectoridin exerts the estrogenic effects via ER-dependent genomic pathway and GPR30-dependent nongenomic pathway [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 611-40-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0791.
2-hydroxyisoflavanone dehydratase
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously. Group: Enzymes. Synonyms: 2,7,4'-trihydroxyisoflavanone hydro-lyase; 2,7,4'-trihydroxyisoflavanone hydro-lyase (daidzein-forming). Enzyme Commission Number: EC 4.2.1.105. CAS No. 166800-10-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4944; 2-hydroxyisoflavanone dehydratase; EC 4.2.1.105; 166800-10-8; 2,7,4'-trihydroxyisoflavanone hydro-lyase; 2,7,4'-trihydroxyisoflavanone hydro-lyase (daidzein-forming). Cat No: EXWM-4944.
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