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| Product | Description | |
|---|---|---|
| 27-Carboxy-7-keto cholesterol | 27-Carboxy-7-keto cholesterol. Group: Biochemicals. Alternative Names: (3b)-3-Hydroxy-7-oxocholest-5-en-26-oic acid. Grades: Highly Purified. CAS No. 148988-30-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C27H42O4. US Biological Life Sciences. |  Worldwide |
| 27-Carboxy-7-keto Cholesterol | 27-Carboxy-7-keto Cholesterol is a cytostatic sterol for treatment of cancer and other conditions associated with rapidly growing cells. Synonyms: (3β)-3-Hydroxy-7-oxocholest-5-en-26-oic Acid. Grades: > 95%. CAS No. 148988-30-1. Molecular formula: C27H42O4. Mole weight: 430.63. |  |
| 27-Hydroxy-7-keto cholesterol | 27-Hydroxy-7-keto cholesterol. Group: Biochemicals. Alternative Names: (3b)-3,26-Dihydroxycholest-5-en-7-one. Grades: Highly Purified. CAS No. 148988-28-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C27H44O3. US Biological Life Sciences. | Worldwide |
| 27-Hydroxy-7-keto Cholesterol | 27-Hydroxy-7-keto Cholesterol is a cytostatic sterol for treatment of cancer and other conditions associated with rapidly growing cells. Synonyms: (3β)-3,26-Dihydroxycholest-5-en-7-one. Grades: > 95%. CAS No. 148988-28-7. Molecular formula: C27H44O3. Mole weight: 416.64. | |
| 27-Nor-25-ketocholesterol | 27-Nor-25-ketocholesterol is an intermediate in the synthesis of hydroxy derivatives of cholesterol (C432501). Group: Biochemicals. Grades: Highly Purified. CAS No. 7494-34-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C26H42O2. US Biological Life Sciences. | Worldwide |
| 3-Keto Cholesterol | A metabolite of Cholesterol. Group: Biochemicals. Alternative Names: Cholest-5-en-3-one; ?5-Cholesten-3-one;3-Oxocholest-5-ene; 5-Cholestenone; NSC 118979. Grades: Highly Purified. CAS No. 601-54-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 7Keto-25-hydroxy cholesterol | 7-Keto-25-Hydroxy cholesterol is an oxysterol and a proposed metabolite of 7-keto cholesterol and 7-dehydro cholesterol. Synonyms: 25-hydroxy 7-keto cholesterol; 7-keto-25-hydroxycholesterol; cholest-5-ene-7-one-3ß,25-diol; 3β,25-dihydroxy-cholest-5-en-7-one. Grades: ≥95%. CAS No. 64907-23-9. Molecular formula: C27H44O3. Mole weight: 416.64. | |
| 7-Ketocholesterol | 7-Ketocholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL. It is also a metabolite of Cholesterol. Synonyms: (3β)-3-Hydroxycholest-5-en-7-one; 3β-Hydroxycholest-5-en-7-one; 7-Oxocholesterol; Cholest-5-en-3β-ol-7-one; 7-Oxocholesterol; 7-oxo-cholesterol. Grades: > 95%. CAS No. 566-28-9. Molecular formula: C27H44O2. Mole weight: 400.64. | |
| 7-Ketocholesterol | 7-Ketocholesterol is an oxidation product of cholesterol, widely present in atherosclerotic plaques, and has a stronger atherogenic effect than cholesterol. 7-Ketocholesterol can inhibit the rate-limiting enzymes involved in bile acid and cholesterol synthesis, such as cholesterol 7α-hydroxylase and HMG-CoA reductase. 7-Ketocholesterol exhibits pro-inflammatory effects both in vivo and in vitro and can induce cell apoptosis ( apoptosis ) [1]. Uses: Scientific research. Group: Natural products. CAS No. 566-28-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113342. |  |
| 7-Keto Cholesterol | A metabolite of Cholesterol. Group: Biochemicals. Alternative Names: (3 β)-. Grades: Highly Purified. CAS No. 566-28-9. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 7-Keto Cholesterol-d7 | 7-Keto Cholesterol-d 7 is the deuterium labeled 7-Keto Cholesterol[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 127684-08-6. Pack Sizes: 1 mg. Product ID: HY-113342S. | |
| 12-Ketochenodeoxycholic acid | 12-Ketochenodeoxycholic acid 12 is a direct precursor of cholodeoxycholic acid (CDCA). Cholodeoxycholic acid is used to cholesterol gallstones and has chemotherapeutic properties that dissolve gallstones [1]. Uses: Scientific research. Group: Natural products. CAS No. 2458-8-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W403933. | |
| 2-Hexadecanone | 2-Hexadecanone (CAS# 18787-63-8) is a saturated long chain alkyl ketone. Studies show that 2-Hexadecanone is an excellent anticholesteremic that reduces serum cholesterol levels significantly without altering triglyceride levels. 2-Hexadecanone is a volatile constituent found in cooked meats as well as in essential oils from various flowers and plants. Synonyms: hexadecan-2-one. CAS No. 18787-63-8. Molecular formula: C16H32O. Mole weight: 240.42. | |
| 3β-hydroxysteroid 3-dehydrogenase | The enzyme acts on multiple 3β-hydroxysteroids. Participates in the biosynthesis of zemosterol and cholesterol, where it catalyses the reaction in the opposite direction to that shown. The mammalian enzyme is bifunctional and also catalyses EC 1.1.1.62, 17β-estradiol 17-dehydrogenase. Group: Enzymes. Synonyms: 3-keto-steroid reductase; 3-KSR; HSD17B7 (gene name); ERG27 (gene name). Enzyme Commission Number: EC 1.1.1.270. CAS No. 42616-29-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0177; 3β-hydroxysteroid 3-dehydrogenase; EC 1.1.1.270; 42616-29-5; 3-keto-steroid reductase; 3-KSR; HSD17B7 (gene name); ERG27 (gene name). Cat No: EXWM-0177. |  |
| 3-ketosteroid 9α-monooxygenase | The enzyme is involved in the cholesterol degradation pathway of several bacterial pathogens, such as Mycobacterium tuberculosis. It is a two-component system consisting of a terminal oxygenase (KshA) and a ferredoxin reductase (KshB). The oxygenase contains a Rieske-type iron-sulfur center and non-heme iron. The reductase component is a flavoprotein containing an NAD-binding domain and a plant-type iron-sulfur cluster. The product of the enzyme is unstable, and spontaneously converts to 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione. Group: Enzymes. Synonyms: KshAB; 3-ketosteroid 9α-hydroxylase. Enzyme Commission Number: EC 1.14.13.142. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0742; 3-ketosteroid 9α-monooxygenase; EC 1.14.13.142; KshAB; 3-ketosteroid 9α-hydroxylase. Cat No: EXWM-0742. | |
| 6-Oxolithocholic acid | 6-Oxolithocholic acid is a bile acid metabolite derived from Lithocholic acid (HY-B0172). 6-Oxolithocholic acid has high cytotoxicity and can induce apoptosis , especially in hepatocytes. 6-Oxolithocholic acid can participate in the regulation of bile acid metabolism and synthesis and affect the metabolic pathway of cholesterol. 6-Oxolithocholic acid can be used to study the role of bile acids in health and disease, especially in the context of digestive and liver diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 6-Ketolithocholic acid. CAS No. 2393-61-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-W587530. | |
| 7-Ketolithocholic acid | 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 3α-Hydroxy-7-oxo-5β-cholanic acid. CAS No. 4651-67-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W018512. | |
| 7-Oxo Cholesterol 3-Acetate | Intermediate in the preparation of various Cholesterol derivatives and metabolites. Group: Biochemicals. Alternative Names: (3 β)-3-(Acetyloxy)cholest-5-en-7-one; 3 β-Hydroxy-cholest-5-en-7-one Acetate; 7-Ketocholesteryl Acetate; 7-Oxocholest-5-en-3 β-yl Acetate; 7-Oxocholesteryl Acetate; NSC 59469. Grades: Highly Purified. CAS No. 809-51-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 7-Oxo Cholesterol-d7 3-Acetate | Intermediate in the preparation of various Cholesterol derivatives and metabolites. Group: Biochemicals. Alternative Names: (3 β)-3-(Acetyloxy)cholest-5-en-7-one-d7; 3 β-Hydroxy-cholest-5-en-7-one-d7 Acetate; 7-Ketocholesteryl-d7 Acetate; 7-Oxocholest-5-en-3 β-yl-d7 Acetate; 7-Oxocholesteryl-d7 Acetate; NSC 59469-d7. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Acetyl coenzyme A | Acetyl coenzyme A is the precursor to HMG CoA, an essential component in the synthesis of cholesterol and ketone. Synonyms: Acetyl-CoA; S-Acetyl coenzyme A; AcCoA; Coenzyme A, S-acetate; S-acetyl-CoA. CAS No. 72-89-9. Molecular formula: C23H38N7O17P3S. Mole weight: 809.57. | |
| cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming] | This enzyme, found in several bacterial pathogens, is involved in degradation of the host's cholesterol. It catalyses the hydroxylation of the C-26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate, initiating the degradation of the alkyl side-chain of cholesterol. The products are exclusively in the (25S) configuration. It is a two-component system consisting of a P-450 (heme thiolate) oxygenase (Cyp125) and a ferredoxin reductase (most likely KshB, which is also a part of EC 1.14.13.142, 3-ketosteroid 9α-monooxygenase). The enzyme also accepts cholesterol as a substrate. cf. EC 1.14.13.221, cholest-4-en-3-one 27-monooxygenase. Group: Enzymes. Synonyms: CYP125; CYP125A1; cholest-4-en-3-one 27-monooxygenase (misleading); cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxyl. Enzyme Commission Number: EC 1.14.13.141. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0741; cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]; EC 1.14.13.141; CYP125; CYP125A1; cholest-4-en-3-one 27-monooxygenase (misleading); cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxylating); cholest-4-en-3-one 26-monooxygenase (ambiguous). Cat No: EXWM-0741. | |
| Cholesterol Dehydrogenase from Nocardia sp. | Cholesterol dehydrogenase is an enzyme that uses nicotinamide adenine dinucleotide/nicotinamide adenine dinucleotide phosphate (NAD(P)) as its cofactor in oxidizing cholesterol to form cholest-4-en-3-one. This enzyme oxidizes the hydroxyl group at the 3 position of the sterol ring to form a ketone. Group: Enzymes. Synonyms: Cholesterol Dehydrogenase; CDH. CAS No. 67775-34-2. Activity: 10U/mg-solid or more. Storage: at -20°C. Form: Freeze dried powder. Source: Nocardia sp. Cholesterol Dehydrogenase; CDH. Cat No: NATE-0892. | |
| cholesterol oxidase | Contains FAD. Cholesterol oxidases are secreted bacterial bifunctional enzymes that catalyse the first two steps in the degradation of cholesterol. The enzyme catalyses the oxidation of the 3β-hydroxyl group to a keto group, and the isomerization of the double bond in the oxidized steroid ring system from the Δ5 position to Δ6 position (cf. EC 5.3.3.1, steroid Δ-isomerase). Group: Enzymes. Synonyms: cholesterol- O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase. Enzyme Commission Number: EC 1.1.3.6. CAS No. 9028-76-6. CHOD. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0424; cholesterol oxidase; EC 1.1.3.6; 9028-76-6; cholesterol- O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase. Cat No: EXWM-0424. | |
| DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt | DL-3-Hydroxy-3-methylglutaryl coenzyme is a trisodium salt key intermediate in the biosynthesis of cholesterol, ketone bodies and terpenes. Applications: An intermediate in biosynthesis. Group: Coenzymes. Synonyms: DL-3-Hydroxy-3-methylglutaryl coenzyme A sodium salt. CAS No. 103476-21-7. Purity: ≥95%. Mole weight: 977.62. Appearance: Crystalline. Form: Solid. DL-3-Hydroxy-3-methylglutaryl coenzyme A sodium salt; DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt; 103476-21-7. Cat No: COEC-042. | |
| Ezetimibe ketone | Ezetimibe ketone (EZM-K) is a phase-I metabolite of Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 ( NPC1L1 ) inhibitor, and is a potent Nrf2 activator. Ezetimibe is a potent cholesterol absorption inhibitor [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EZM-K. CAS No. 191330-56-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-133114. | |
| Native Nocardia sp. Cholesterol Dehydrogenase | Cholesterol dehydrogenase is an enzyme that uses nicotinamide adenine dinucleotide/nicotinamide adenine dinucleotide phosphate (NAD(P)) as its cofactor in oxidizing cholesterol to form cholest-4-en-3-one. This enzyme oxidizes the hydroxyl group at the 3 position of the sterol ring to form a ketone. Applications: Used in the formulation of cholesterol testing reagents or in biosensor applications. Group: Enzymes. Synonyms: Cholesterol Dehydrogenase; CDH. CDH. Mole weight: 37 kDa (SDS-PAGE). Activity: > 5 U/mg. Appearance: Light yellow to brown powder. Form: Freeze dried powder. Source: Nocardia sp. Cholesterol Dehydrogenase; CDH. Cat No: NATE-0892. | |
| steroid Δ-isomerase | This activity is catalysed by several distinct enzymes (cf. EC 1.1.3.6, cholesterol oxidase and EC 1.1.1.145, 3-hydroxy-5-steroid dehydrogenase). Group: Enzymes. Synonyms: hydroxysteroid isomerase; steroid isomerase; Δ5-ketosteroid isomerase; Δ5(or Δ4)-3-keto steroid isomerase; Δ5-steroid isomerase; 3-oxosteroid isomerase; Δ5-3-keto steroid isomerase; Δ5-3-oxosteroid isomerase. Enzyme Commission Number: EC 5.3.3.1. CAS No. 9031-36-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5489; steroid Δ-isomerase; EC 5.3.3.1; 9031-36-1; hydroxysteroid isomerase; steroid isomerase; Δ5-ketosteroid isomerase; Δ5(or Δ4)-3-keto steroid isomerase; Δ5-steroid isomerase; 3-oxosteroid isomerase; Δ5-3-keto steroid isomerase; Δ5-3-oxosteroid isomerase. Cat No: EXWM-5489. | |
| 6-Ketocholestanol (5a-Cholestan-6-one) | An oxygenated cholesterol which can be used as a ligand for cytosolic-nuclear tumor promoter binding protein. Group: Biochemicals. Alternative Names: 5a-Cholestan-6-one. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Ezetimibe Ketone | Phase-I metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: > 95%. CAS No. 191330-56-0. Molecular formula: C24H19F2NO3. Mole weight: 407.42. | |
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