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KN 93. Group: Biochemicals. Grades: Purified. CAS No. 139298-40-1. Pack Sizes: 1mg. US Biological Life Sciences.
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KN 93 phosphate
KN 93 phosphate. Group: Biochemicals. Grades: Purified. CAS No. 1188890-41-6. Pack Sizes: 1mg. US Biological Life Sciences.
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1-Bromo-2,5,8,11,14-heptadecapentayne
1-Bromo-2,5,8,11,14-heptadecapentayne is an unsaturated compound that is related to Arachidonic acid (A3303). Arachidonic acid is membrane phospholipid component of mammalian cells that is known to give the cell membranes their correct fluidity. Arachidonic acid also directly activates potassium channels in smooth muscle. Group: Biochemicals. Grades: Highly Purified. CAS No. 93322-84-0. Pack Sizes: 25mg, 250mg. Molecular Formula: C17H15Br, Molecular Weight: 299.2. US Biological Life Sciences.
Worldwide
2,5,8,11,14-Heptadecapentayn-1-ol
2,5,8,11,14-Heptadecapentayn-1-ol is an unsaturated compound that is related to Arachidonic acid (A3303). Arachidonic acid is membrane phospholipid component of mammalian cells that is known to give the cell membranes their correct fluidity. Arachidonic acid also directly activates potassium channels in smooth muscle. Group: Biochemicals. Grades: Highly Purified. CAS No. 93318-79-7. Pack Sizes: 25mg, 250mg. Molecular Formula: C17H16O, Molecular Weight: 236.31. US Biological Life Sciences.
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8-[(6-Amino)hexyl]-amino-cAMP - ATTO-620
8-[(6-Amino)hexyl]-amino-cAMP - ATTO-620, an exemplary fluorescent labeling probe essential in shedding light on cAMP signaling pathways, is widely used in biomedical research. Labeling of cell membranes and intracellular compartments using this product is indeed suitable, thereby amplifying knowledge about biomedical mechanisms of interest. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 620, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 620 (free acid). Mole weight: 936.39 (free acid).
BI 6015
BI 6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that suppresses expression of known HNF4α target genes. BI 6015 produces cytotoxicity in a range of tumor cell lines, including human hepatocellular carcinoma. Synonyms: BI6015; BI 6015; BI-6015. 2-Methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-1H-benzimidazole. Grade: ≥98% by HPLC. CAS No. 93987-29-2. Molecular formula: C15H13N3O4S. Mole weight: 331.35.
BI-6015
BI-6015 is a hepatocyte nuclear factor 4? (HNF4?) antagonist that can inhibit the expression of known HNF4? target genes. BI6015 represses insulin promoter activity through HNF4? antagonism. BI-6015 can be used for the research of cancer and diabetes[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 93987-29-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108469.
Cobimetinib racemate
Cobimetinib racemate is a selective inhibitor of MEK. It is also known as mitogen activated protein kinase kinase (MAPKK) and is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors. Synonyms: GDC-0973 racemate; XL-518; GDC 0973 racemate; XL 518; GDC0973 racemate; XL518. Grade: >98%. CAS No. 934662-91-6. Molecular formula: C21H21F3IN3O2. Mole weight: 531.31.
Cobimetinib (R-enantiomer)
Cobimetinib (R-enantiomer) is a selective inhibitor of MEK. It is also known as mitogen activated protein kinase kinase (MAPKK) and is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors. Synonyms: GDC-0973 R-enantiomer; XL-518 R-enantiomer; GDC0973 R-enantiomer; XL518 R-enantiomer; GDC 0973 R-enantiomer; XL 518 R-enantiomer. Grade: >98%. CAS No. 934660-94-3. Molecular formula: C21H21F3IN3O2. Mole weight: 531.31.
Elinogrel
Elinogrel, also known as PRT 060128, is P2Y12 inhibitor. Similarly to ticagrelor and in contrast to clopidogrel, elinogrel was a reversible inhibitor that acted fast and short (for about 12 hours), and it was not a prodrug but pharmacologically active itself. The substance was used in form of its potassium salt, intravenously for acute treatment and orally for long-term treatment. Development was terminated in 2012. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PRT 060128; PRT-060128; PRT060128; Elinogrel. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 936500-94-6. Molecular formula: C20H15ClFN5O5S2. Mole weight: 523.94. Purity: >98%. IUPACName: 5-chloro-N-((4-(6-fluoro-7-(methylamino)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)phenyl)carbamoyl)thiophene-2-sulfonamide. Canonical SMILES: O=C(NC1=CC=C(N2C(NC3=C(C=C(F)C(NC)=C3)C2=O)=O)C=C1)NS(=O)(C4=CC=C(Cl)S4)=O. Product ID: ACM936500946-1. Alfa Chemistry ISO 9001:2015 Certified.
Fazarabine
Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis, resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug. Synonyms: CCRIS 93; CCRIS-93; CCRIS93; NSC 281272; NSC-281272; NSC281272; Ara-AC; 5-Azacytosine arabinoside; 1-beta-D-Arabinofuranosyl-5-azacytosine. CAS No. 65886-71-7. Molecular formula: C8H12N4O5. Mole weight: 244.20.
Fluorescent Brightener 71-d10
Fluorescent Brightener 71-d10 is deuterium labelled form of Fluorescent Brightener 71 (F596080). Fluorescent (optical) brighteners are known for their characteristics of protecting baculoviruses against deactivation by UV light and enhancing the activity of these agents as microbial insecticides on hosts and semipermissive hosts. Fluorescent brighteners improve the bioinsecticidal activity of Anticarsia gemmatalis nucleopolyhedrovirus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C40H28D10N12Na2O8S2, Molecular Weight: 934.98. US Biological Life Sciences.
Worldwide
Heparin
Heparin, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. The common form is the sodium salt form. Synonyms: [2-Deoxy-2-sulfoamino-6-O-sulfo-4-O-(2-O-sulfo-a-L-idopyranuronosyl)-a-D-glucopyranose]n; Adomiparin; Ardeparin; Arteven; AVE 5026; Bemiparin; Centaxarin; Certoparin; Clevarin; Clivarin; Clivarine; CY 216; CY 222; Dalteparin; Deligoparin; F 202; Fluxum; FR 860; Fragmin A; Fragmin B; Fraxiparin; Gammaparin; H 5284; H 9399; Hapacarin; Heparin subcutan; Heparin sulfate; Heparinic acid; Heparins; KB 101; Leparan; LipoHep Forte; Livaracine; M 118; M 402 (heparin); Mono-embolex; Multiparin; Nadroparin; Nadroparine; Necuparanib; Novoheparin; Octaparin; OP 386; OP 622; Pabyrn; Parnaparin; Parvoparin; Reviparin; Sandoparin; Semuloparin; Subeparin; Sublingula; Tafoxiparin; Tinzaparin; Triofiban; Vetren; Vitrum AB; α-Heparin. Grade: >98%. CAS No. 9005-49-6.
HT-61
HT-61, also known as HY-50A, is a pyrroloquinolone antibiotic potentially for the treatment of staphylococcal infections. HT61 was effective at reducing biofilm viability and was associated with increased expression of cell wall stress and division proteins, confirming its potential as a treatment for S. aureus biofilm infections. HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: HT-61; HT61; HT 61; HY-50A; HY 50A; HY50A. Product Category: Others. Appearance: Solid powder. CAS No. 936622-80-9. Molecular formula: C26H24N2O. Mole weight: 380.49. Purity: >98%. IUPACName: 4-methyl-1-phenethyl-8-phenoxy-2,3-dihydro-1H-pyrrolo[3,2-c]quinoline. Canonical SMILES: CC1=NC2=CC=C(OC3=CC=CC=C3)C=C2C4=C1CCN4CCC5=CC=CC=C5. Product ID: ACM936622809. Alfa Chemistry ISO 9001:2015 Certified. Categories: HQ-6.
Hydrocinnamic acid-[d9]
Hydrocinnamic acid-[d9] is the labelled analogue of Hydrocinnamic acid. Hydrocinnamic acid, also known as phenylpropanoate or dihydrocinnamate, belongs to the class of organic compounds known as phenylpropanoic acids. Hydrocinnamic acid has a wide variety of uses including cosmetics, food additives, and pharmaceuticals. Synonyms: 3-Phenylpropionic-d9 acid; Hydrocinnamic acid-d9,OH; Benzene-d5-propanoic-d4acid (9CI); hydrocinnamic acid-d9; HYDROCINNAMIC-D9 ACID. Grade: 98% atom D. CAS No. 93131-15-8. Molecular formula: C9HD9O2. Mole weight: 159.23.
Ibrutinib, Free Base
Ibrutinib, also known as PCI-32765, is a selective and irreversible inhibitor of the enzyme Bruton's tyrosine kinase (BTK). It inhibited BTK potently, with an IC50 of 0.72 nM in enzymology assays and with an IC50 of 10 nM in cellular assay with Ramos cells. It demonstrated preference toward BTK over closely related kinases, blocked B cell function and BTK-dependent processes, and demonstrated clear efficacy in a mouse arthritis model. Young P.R., et al. "Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase." ChemMedChem. 2: 58-61 (2007). Group: Biochemicals. Alternative Names: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one; PCI 32765; PCI 32765-00; CRA 032765; (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one; Imbruvica. Grades: Purified. CAS No. 936563-96-1. Pack Sizes: 5mg, 25mg, 50mg. US Biological Life Sciences.
Panax notoginseng extract is prepared from the species of the genus Panax, also known as sanqi extract powder. Panax notoginseng extract powder contain high potency notoginsenoside, Ginsenoside Rb1, Ginsenoside Rg1, Ginsenoside Rd, Ginsenoside Re, and Ginsenoside Rb2, which are most active ingredients impacting on your overall health and nutritionally support healthy heart function, blood circulation, and performance. Group: Others. Mole weight: 933.14. Panax Notoginseng Extract; Panax Pseudo-Ginseng Wall. Var. Cat No: EXTC-016.
scutelarin
From the venom of the Taipan snake (Oxyuranus scutellatus). Converts prothrombin to thrombin. Specificity is similar to that of Factor Xa (EC 3.4.21.6). However, unlike Factor Xa this enzyme can cleave its target in the absence of coagulation Factor Va. Activity is potentiated by phospholipid and Ca2+ which binds via γ-carboxyglutamic acid residues. Similar enzymes are known from the venom of other Australian elapid snakes, including Pseudonaja textilis textilis, Oxyuranus microlepidotus and Demansia nuchalis affinis. Group: Enzymes. Synonyms: taipan activator; Oxyuranus scutellatus prothrombin-activating proteinase. Enzyme Commission Number: EC 3.4.21.60. CAS No. 93389-45-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4151; scutelarin; EC 3.4.21.60; 93389-45-8; taipan activator; Oxyuranus scutellatus prothrombin-activating proteinase. Cat No: EXWM-4151.
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