Kynurenine Suppliers USA
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Product | Description | |
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KMO Inhibitor I, Ro 61-8048 (Kynurenine-3-Monooxygenase Inhibitor I, Ro 61-8048 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]-benzenesulfonamide Dimethoxy-nitrophenyl-thiazolyl-benzenesulfonamide, Kynurenine-3-Hydroxylase Inhibitor I, Ro 61-8048) Quick inquiry Where to buy Suppliers range | A cell-permeable thiazolyl Benzene sulfonamide compound that acts as a potent, competitive and reversible inhibitor of kynurenine-3-monooxygenase activity (Ki=4.8nM; IC50=37nM). Reported to increase the circulating levels of kynurenic acid (KYNA), an excitatory amino acid receptors antagonist, lower reactive oxygen species [ROS], reduce neuronal loss and enhance the survival rate in several neuronal disease models. An orally bioavilable KMO Inhibitor II, JM6, a prodrug of Ro 61-8048 is also available. Group: Biochemicals. Grades: Highly Purified. CAS No. 199666-03-0. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S?, Molecular Weight: 421.5. US Biological Life Sciences. | Worldwide |
3-Hydroxy-DL-kynurenine Quick inquiry Where to buy Suppliers range | 3-Hydroxy-DL-kynurenine is an active metabolite of tryptophan. Synonyms: Benzenebutanoic acid, α,2-diamino-3-hydroxy-γ-oxo-; Alanine, 3-(3-hydroxyanthraniloyl)-; α,2-Diamino-3-hydroxy-γ-oxobenzenebutanoic acid; 3-Hydroxykynurenine; DL-3-Hydroxykynurenine; Hydroxykynurenine. Grades: ≥98%. CAS No. 484-78-6. Molecular formula: C10H12N2O4. Mole weight: 224.21. | |
3-Hydroxy-DL-kynurenine Quick inquiry Where to buy Suppliers range | 3-Hydroxy-DL-kynurenine. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 484-78-6. Pack Sizes: 25MG, 100MG, 250MG. Mole weight: 224.21. Catalog: AP484786. | |
3-Hydroxy-DL-kynurenine-(α,β,γ-13C3,α-amino-15N) Quick inquiry Where to buy Suppliers range | ≥98 atom %, ≥95% (CP). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 1MG. Mole weight: 228.18. Catalog: IAR42410385. Assay: ≥95% (CP). | |
4-Chloro Kynurenine Quick inquiry Where to buy Suppliers range | 4-Chloro Kynurenine. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS00481. Format: Neat. | |
4-Chloro Kynurenine-13C2,15N Quick inquiry Where to buy Suppliers range | 7-Cl-kynurenic acid (7-Cl-KYNA) is a potent, selective antagonist of the NMDA/glycine receptor but penetrates poorly through the blood-brain barrier. Its prodrug, L-4-Cl-kynurenine (4-Cl-KYN), readily enters the brain from the circulation and provides antiexcitotoxic neuroprotection after systemic application. Group: Biochemicals. Alternative Names: α,2-Diamino-4-chloro-γ-oxobenzenebutanoic Acid-13C2,15N; (+/-)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
D-Kynurenine Quick inquiry Where to buy Suppliers range | D-Kynurenine. Uses: Amino Acids & Derivatives. Product ID: CP22102. | |
D-Kynurenine Quick inquiry Where to buy Suppliers range | a metabolite of D-tryptophan that is also a bioprecursor of two neuroactive compounds kynurenic acid (KYNA) and 3-hydroxykynurenine. Synonyms: (αR)-α,2-Diamino-γ-oxo-benzenebutanoic Acid; D-3-Anthraniloylalanine; (R)-α,2-Diamino-γ-oxo-benzenebutanoic Acid. Grades: > 95%. CAS No. 13441-51-5. Molecular formula: C10H12N2O3. Mole weight: 208.22. | |
DL-Kynurenine Quick inquiry Where to buy Suppliers range | DL-Kynurenine. Group: Biochemicals. Alternative Names: a,2-Diamino-gamma-oxo. Grades: Highly Purified. CAS No. 343-65-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C10H12N2O3. US Biological Life Sciences. | Worldwide |
DL-Kynurenine Quick inquiry Where to buy Suppliers range | DL-Kynurenine. Uses: Amino Acids & Derivatives. Product ID: CP22103. | |
L-Kynurenine Quick inquiry Where to buy Suppliers range | L-Kynurenine. Group: Biochemicals. Grades: Highly Purified. CAS No. 2922-83-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
L-Kynurenine Quick inquiry Where to buy Suppliers range | L-Kynurenine. Uses: Amino Acids & Derivatives. Product ID: CP22101. | |
L-Kynurenine Quick inquiry Where to buy Suppliers range | a product of constitutive tryptophan catabolism via tryptophan-2,3-dioxygenase in the liver and human gliomas that is associated with the suppression of antitumor immune responses. Synonyms: L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid. Grades: > 95%. CAS No. 2922-83-0. Molecular formula: C10H12N2O3. Mole weight: 208.22. | |
L-Kynurenine Quick inquiry Where to buy Suppliers range | L-Kynurenine. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Alternative Names: L-3-(o-Aminobenzoyl)alanine, Alanine, 3-anthraniloyl-, L- (8CI),Benzenebutanoic acid, α,2-diamino-γ-oxo-, (αS)-, L-Kynurenine, Benzenebutanoic acid, α,2-diamino-γ-oxo-, (S)-, (2S)-4-(2-Aminophenyl)-2-azaniumyl-4-oxobutanoate, (αS)-α,2-Diamino-γ-oxobenzenebutanoic acid, Kynurenin, Kynurenine, 3-Anthraniloylalanine, (S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid. CAS No. 2922-83-0. Pack Sizes: 10MG. IUPAC Name: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid. Molecular formula: C10H12N2O3. Mole weight: 208.21. Catalog: APS2922830. SMILES: N[C@@H](CC(=O)c1ccccc1N)C(=O)O. Format: Neat. Product Type: Impurity. Shipping: Room Temperature. | |
L-Kynurenine 98+% Quick inquiry Where to buy Suppliers range | L-Kynurenine 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
L-Kynurenine-d4 TFA Salt Quick inquiry Where to buy Suppliers range | L-Kynurenine-d4 TFA Salt. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS002132. Format: Neat. Product Type: Stable Isotope Labelled. | |
L-Kynurenine-d4 Trifluoroacetic Acid Salt Quick inquiry Where to buy Suppliers range | L-Kynurenine-d4 Trifluoroacetic Acid Salt. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Pack Sizes: 5MG. Catalog: APS009459. Format: Neat. Product Type: Stable Isotope Labelled. Shipping: Room Temperature. | |
N-Formyl Kynurenine Quick inquiry Where to buy Suppliers range | a photooxidation product of Tryptophan. Synonyms: 2-amino-4-(2-formamidophenyl)-4-oxo-butanoic acid; α-Amino-2-(formylamino)-γ-oxo-Benzenebutanoic Acid; 3-(N-Formylanthraniloyl)alanine; Formylkynurenine; N-Formylkynurenine. Grades: > 95%. CAS No. 1022-31-7. Molecular formula: C11H12N2O4. Mole weight: 236.23. | |
N-Formyl-L-kynurenine Quick inquiry Where to buy Suppliers range | N-Formylkynurenine is a L-kynurenine derivative. Synonyms: (S)-2-Amino-4-(2-formamidophenyl)-4-oxobutanoic acid. CAS No. 3978-11-8. Molecular formula: C11H12N2O4. Mole weight: 236.22. | |
rac 3-Hydroxy Kynurenine-13C2,15N Hydrochloride Salt Quick inquiry Where to buy Suppliers range | rac 3-Hydroxy Kynurenine-13C2,15N Hydrochloride Salt. Uses: For analytical and research use. Group: Building Blocks. Catalog: APS002872. Format: Neat. Product Type: Stable Isotope Labelled. | |
rac 3-Hydroxy Kynurenine Hydrochloride Salt Quick inquiry Where to buy Suppliers range | rac 3-Hydroxy Kynurenine Hydrochloride Salt. Uses: For analytical and research use. Group: Building Blocks. Catalog: APS002871. Format: Neat. Product Type: Metabolite. | |
rac α-Methyl Kynurenine Quick inquiry Where to buy Suppliers range | rac α-Methyl Kynurenine is an impurity of rac Kyurenine (K661000), a tryptophan metabolite and the precursor of an antagonist of N-methyl-aspartate receptor, Kynurenic acid (K660500). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
rac Kynurenine Quick inquiry Where to buy Suppliers range | rac Kynurenine. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. CAS No. 343-65-7. Pack Sizes: 5MG. IUPAC Name: 2-amino-4-(2-aminophenyl)-4-oxobutanoic acid. Molecular formula: C10H12N2O3. Mole weight: 208.21. Catalog: APS343657. SMILES: NC(CC(=O)c1ccccc1N)C(=O)O. Format: Neat. Shipping: Room Temperature. | |
rac Kynurenine Quick inquiry Where to buy Suppliers range | A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. Group: Biochemicals. Alternative Names: α,2-Diamino-γ-oxo. Grades: Highly Purified. CAS No. 343-65-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
rac-Kynurenine Quick inquiry Where to buy Suppliers range | A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. Synonyms: 2-Amino-3-(2-aminobenzoyl)propionic acid, 2-Amino-4-(2-aminophenyl)-4-oxobutyric acid; DL-Kynurenine. Grades: > 95%. CAS No. 343-65-7. Molecular formula: C10H12N2O. Mole weight: 208.22. | |
1-[2-Nitro-3- (phenylmethoxy) phenyl]ethanone Quick inquiry Where to buy Suppliers range | 1-[2-Nitro-3- (phenylmethoxy) phenyl]ethanone is an UV degradation product of 3-Hydroxy Kynurenine (H943695), a metabolite of tryptophan. Group: Biochemicals. Grades: Highly Purified. CAS No. 224044-60-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C15H13NO4. US Biological Life Sciences. | Worldwide |
2-Acetamido-2-(2-(2-amino-3-hydroxyphenyl)-2-oxoethyl)malonic Acid Diethyl Ester Quick inquiry Where to buy Suppliers range | 2-Acetamido-2-(2-(2-amino-3-hydroxyphenyl)-2-oxoethyl)malonic Acid Diethyl Ester is an UV degradation product of 3-Hydroxy Kynurenine (H943695), a metabolite of tryptophan. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C17H22N2O7. US Biological Life Sciences. | Worldwide |
2-(Acetylamino)-2-[2-[2-nitro-3-(phenylmethoxy)phenyl]-2-oxoethyl]propanedioic Acid 1,3-Diethyl Ester Quick inquiry Where to buy Suppliers range | 2-(Acetylamino)-2-[2-[2-nitro-3-(phenylmethoxy)phenyl]-2-oxoethyl]propanedioic Acid 1,3-Diethyl Ester is an UV degradation product of 3-Hydroxy Kynurenine (H943695), a metabolite of tryptophan. Group: Biochemicals. Grades: Highly Purified. CAS No. 224044-62-6. Pack Sizes: 5mg, 25mg. Molecular Formula: C24H26N2O9. US Biological Life Sciences. | Worldwide |
2-Amino-3-hydroxybenzoate Potassium Salt Quick inquiry Where to buy Suppliers range | 2-Amino-3-hydroxybenzoate Potassium Salt is an intermediate used in the synthesis of 3-Hydroxyanthranillic Acid-d3 (H801792), which is the labeled analogue of 3-Hydroxyanthranillic Acid, one of the tryptophan metabolites along with the kynurenine pathways. 3-Hydroxyanthranilic Acid has been shown to induce apoptosis in T cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C7H6KNO3, Molecular Weight: 191.23. US Biological Life Sciences. | Worldwide |
2-Amino-5-bromo-3-hydroxybenzoic Acid Quick inquiry Where to buy Suppliers range | 2-Amino-5-bromo-3-hydroxybenzoic Acid is an intermediate used in the synthesis of 3-Hydroxyanthranillic Acid-d3 (H801792), which is the labeled analogue of 3-Hydroxyanthranilic Acid, one of the tryptophan metabolites along the kynurenine pathway. 3-Hydroxyanthranilic Acid has been shown to induce apoptosis in T cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C7H6BrNO3, Molecular Weight: 232.03. US Biological Life Sciences. | Worldwide |
2-Bromo-1-[2-nitro-3- (phenylmethoxy) phenyl]ethanone Quick inquiry Where to buy Suppliers range | 2-Bromo-1-[2-nitro-3- (phenylmethoxy) phenyl]ethanone is an UV degradation product of 3-Hydroxy Kynurenine (H943695), a metabolite of tryptophan. Group: Biochemicals. Grades: Highly Purified. CAS No. 224044-61-5. Pack Sizes: 10mg, 25mg. Molecular Formula: C15H12BrNO4. US Biological Life Sciences. | Worldwide |
2-(Bromomethyl)-1-chloro-3-nitrobenzene Quick inquiry Where to buy Suppliers range | 2-(Bromomethyl)-1-chloro-3-nitrobenzene is a reactant in the synthesis of cyclic hydroxamic acid PF-04859989, a potent and selective inhibitor of human and rat Kynurenine aminotransferase II (KAT II) for treatment of schizophrenia. Group: Biochemicals. Grades: Highly Purified. CAS No. 56433-01-3. Pack Sizes: 100mg, 1g. Molecular Formula: C7H5BrClNO2, Molecular Weight: 250.48. US Biological Life Sciences. | Worldwide |
3-Hydroxyanthranilic Acid Quick inquiry Where to buy Suppliers range | 3-Hydroxy anthranilic acid is an intermediate in the oxidative metabolism of tryptophan in the kynurenine pathway that demonstrates immunoprotective effects. Uses: Free radical scavengers. Synonyms: 2-amino-3-hydroxybenzoic acid; 2-amino-3-hydroxybenzoic acid. Grades: ≥ 98 %. CAS No. 548-93-6. Molecular formula: C7H7NO3. Mole weight: 153.14. | |
BFF 122 Quick inquiry Where to buy Suppliers range | BFF 122 is a potent and selective inhibitor of kynurenine aminotransferase II (IC50 = 1 μM and >30 μM for KAT II and KAT I respectively). Synonyms: BFF122; BFF 122; BFF-122; BF5; (S)-9-(4-Amino-piperazin-1-yl)-8-fluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid. Grades: 99%. CAS No. 1152314-49-2. Molecular formula: C17H19FN4O4. Mole weight: 362.36. | |
Cinnabarinic acid Quick inquiry Where to buy Suppliers range | Cinnabarinic acid is a kynurenine pathway metabolite of tryptophan and is produced by the oxidation of 3-Hydroxyanthranilic acid. It is a metabotropic glutamate receptor (mGlu4R-specific) agonist. It activates mGlu4 receptors in transiently transfected HEK293 cells and is selective over all other mGlu subtypes. It decreases cAMP levels in native cultured cerebellar granule cells. It may be used in studies of the functions of components of the kynurenine metabolic pathway. It leads to loss of apoptosis and mitochondrial respiration. It induces apoptosis in thymocytes by the generation of reactive oxygen species. It also counteracts excitotoxic neuronal cell death induced by NMDA in mixed cultures of cortical cells. It has neuroprotective activity. Synonyms: 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid. Grades: ≥98% by HPLC. CAS No. 606-59-7. Molecular formula: C14H8N2O6. Mole weight: 300.22. | |
INCB024360-analog Quick inquiry Where to buy Suppliers range | Potent competitive inhibitor of IDO1 with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model; This INCB024360-analog decreased kynurenine levels by >50% in plasma and inhibited B16-GM-CSF tumor growth in a dose dependent fashion. Synonyms: INCB-24360; INCB024360; INCB 024360; INCB-024360; indoleamine-2,3-dioxygenase inhibitor INCB024360. Grades: > 98%. CAS No. 914471-09-3. Molecular formula: C9H7ClFN5O2. Mole weight: 271.64. | |
JM-6 Quick inquiry Where to buy Suppliers range | JM6 is a prodrug inhibitor of kynurenine 3-monooxygenase (KMO). It could increase kynurenic acid levels and reduces extracellular glutamate in the brain. It prevents spatial memory deficits, anxiety-related behavior, and synaptic loss in mouse model of Alzheimer disease. It also extends life span, prevents synaptic loss, and decreases microglial activation in a mouse model of Huntington's disease. It also plays an important role in the inhibitory effects towards kynurenine 3-monooxygenase in blood ameliorates neurodegeneration, including Alzheimer's and Huntington's diseases. Uses: Jm6 plays an important role in the inhibitory effects towards kynurenine 3-monooxygenase in blood ameliorates neurodegeneration, including alzheimer's and huntington's diseases. Synonyms: JM6; JM-6; JM 6. 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-2-thiazolyl]-benzenesulfonamide;2-(3,4-Dimethoxybenzenesulfonylamino)-4-(3-nitrophenyl)-5-(piperidin-1-yl)methylthiazole. Grades: >98 %. CAS No. 1008119-83-2. Molecular formula: C23H26N4O6S2. Mole weight: 518.60. | |
NLG-919 Quick inquiry Where to buy Suppliers range | NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), a cytosolic enzyme responsible for the oxidation of the essential amino acid tryptophan into kynurenine. By inhibiting IDO1 and decreasing kynurenine in tumor cells, this agent increases tryptophan levels, restores the proliferation and activation of various immune cells, including dendritic cells (DCs), natural killer (NK) cells, T-lymphocytes, and causes a reduction in tumor-associated regulatory T-cells (Tregs). Synonyms: GDC0919; GDC-0919; GDC 0919; NLG919; NLG 919; NLG-919; RG6078; RG-6078; RG 6078. Grades: > 98%. CAS No. 1402836-58-1. Molecular formula: C18H22N2O. Mole weight: 282.38. | |
Ro 61-8048 Quick inquiry Where to buy Suppliers range | Potent and competitive kynurenine 3-hydroxylase inhibitor (IC50 = 37 nM). Shows antidystonic, anticonvulsant and neuroprotective effects in vivo. Blood-brain barrier permeable. Orally active. Synonyms: Ro61-8048; Ro 61-8048; Ro-61-8048; Ro618048; Ro 618048; Ro-618048. Grades: >98%. CAS No. 199666-03-0. Molecular formula: C17H15N3O6S2. Mole weight: 421.45. | |
UPF-648 Quick inquiry Where to buy Suppliers range | Potent and selective inhibitor of kynurenine-3-monooxygenase (KMO, or kynurenine hydroxylase) activity (IC50: 20 nM); Active (+)-(1S,2S)-enantiomer; Useful tool for research on cognitive enhancement and neuroprotection in the brain. Synonyms: UPF-648; UPF 648; UPF648. Grades: >98%. CAS No. 213400-34-1. Molecular formula: C11H8Cl2O3. Mole weight: 259.09. | |
UPF-648 sodium salt Quick inquiry Where to buy Suppliers range | UPF-648 sodium salt is a potent kynurenine 3-monooxygenase (KMO) inhibitor; exhibits highly active at 1 uM (81 ± 10% KMO inhibition); ineffective at blocking KAT activity. Synonyms: UPF-648 sodium salt; UPF 648 sodium salt; UPF648 sodium salt. Grades: >98%. CAS No. 1465017-87-1. Molecular formula: C11H7Cl2NaO3. Mole weight: 281.07. |