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| Product | Description | |
|---|---|---|
| Lanosterol | Lanosterol, an amphipathic molecule, that is produced by lanosterol synthase (LSS). It is enriched in the lens. Alternative Names: Lanosta-8,24-dien-3beta-ol. CAS No. 79-63-0. Molecular formula: C30H50O. Mole weight: 426.72. Appearance: White to light-yellow powder. Purity: 0.98. IUPACName: (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol. Canonical SMILES: C[C@H] (CCC=C (C)C)[C@H]1CC[C@@]2 ([C@@]1 (CCC3=C2CC[C@@H]4[C@@]3 (CC[C@@H] (C4 (C)C)O)C)C)C. Density: 0.98g/cm³. ECNumber: 201-214-9. Catalog: ACM79630. |  |
| Lanosterol | Lanosterol Inhibitor. Uses: Scientific use. Product Category: T4970. CAS No. 79-63-0. |  |
| Lanosterol | Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol suppresses the aggregation and cytotoxicity of misfolded proteins linked with neurodegenerative diseases [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 79-63-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W020033. |  |
| Lanosterol | Lanosterol - Product ID: NST-10-82. Category: Triterpens. Alternative Names: Lanosta-8,24-dien-3?-ol. Purity: 98%. Test method: HPLC. CAS No. 79-63-0. Pack Sizes: 10g, 20g, 50g, 100g. Appearance: White to beige coloured Powder. Molecular formula: C30H50O. Mole weight: 426.73. Storage: +2 +8 °C. |  |
| Lanosterol-d6 | Lanosterol-d 6 is deuterium labeled Lanosterol. Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol s. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 28290-39-3. Pack Sizes: 100 μg; 1 mg. Product ID: HY-W020033S. | |
| lanosterol synthase | Lanosterol synthase is an oxidosqualene cyclase (OSC) enzyme that converts (S)-2,3-oxidosqualene to a protosterol cation and finally to lanosterol. Lanosterol is a key four-ringed intermediate in cholesterol biosynthesis. In humans, lanosterol synthase is encoded by the LSS gene. Group: Enzymes. Synonyms: 2,3-epoxysqualene lanosterol cyclase; squalene-2,3-oxide-lanosterol cyclase; lanosterol 2,3-oxidosqualene cyclase; squalene 2,3-epoxide:lanosterol cyclase; 2,3-oxidosqualene sterol cyclase; oxidosqualene cyclase; 2,3-oxidosqualene cyclase; 2,3-oxidosqualene-lanosterol cyclase; oxidosqualene-lanosterol cyclase; squalene epoxidase-cyclase; (S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming). Enzyme Commission Number: EC 5.4.99.7. CAS No. 9032-71-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5607; lanosterol synthase; EC 5.4.99.7; 9032-71-7; 2,3-epoxysqualene lanosterol cyclase; squalene-2,3-oxide-lanosterol cyclase; lanosterol 2,3-oxidosqualene cyclase; squalene 2,3-epoxide:lanosterol cyclase; 2,3-oxidosqualene sterol cyclase; oxidosqualene cyclase; 2,3-oxidosqualene cyclase; 2,3-oxidosqualene-lanosterol cyclase; oxidosqualene-lanosterol cyclase; squalene epoxidase-cyclase; (S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming). Cat No: EXWM-5607. |  |
| 14-Demethyl-lanosterol-d6 | Steroids2H Labeled Compounds. Alternative Names: 26,26,26,27,27,27-Hexadeuterio-dimethyl cholest-8(9),24-dien-3ß-ol (T-MAS-d6). CAS No. 1246298-30-5. Molecular formula: C29H42D6O. Mole weight: 418.73. Catalog: ACM1246298305. | |
| 1,1'-(((2R,2'R,4R,4'R)-4,4'-(oxybis(methylene))bis(2-(2,4-difluoro phenyl)tetrahydrofuran-4,2-diyl))bis(methylene))bis(1H-1,2,4-triazole) | 1,1'-(((2R,2'R,4R,4'R)-4,4'-(oxybis(methylene))bis(2-(2,4-difluoro phenyl)tetrahydrofuran-4,2-diyl))bis(methylene))bis(1H-1,2,4-triazole) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 2256739-22-5. Molecular formula: C28H28F4N6O3. Mole weight: 572.56. |  |
| 1-((2R,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one | 1-((2R,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 2243786-01-6. Molecular formula: C30H35N5O3. Mole weight: 513.64. | |
| 1-((2R,3S)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one | 1-((2R,3S)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 2243786-00-5. Molecular formula: C30H35N5O3. Mole weight: 513.64. | |
| 1-((2S,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one | 1-((2S,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 2243786-02-7. Molecular formula: C30H35N5O3. Mole weight: 513.64. | |
| 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine | 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-[4-(4-Aminophenyl)-1-piperazinyl]phendiamineol; 4-[4-(4-aminophenyl)-1-piperazinyl]phenol. Grades: >95%. CAS No. 74853-08-0. Molecular formula: C16H19N3O. Mole weight: 269.34. | |
| 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-O-methoxymethyl-4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one | 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-O-methoxymethyl-4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: [S-(R*,R*)]-2-[1-Ethyl-2-(phenylmethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-O-methoxymethyl-4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one. CAS No. 1246815-19-9. Molecular formula: C32H39N5O4. Mole weight: 557.68. | |
| (2R,4R)-rel-2,4-Bis(2',4'-difluorophenyl)-2,4-dihydroxypentane | (2R,4R)-rel-2,4-Bis(2',4'-difluorophenyl)-2,4-dihydroxypentane is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: (2R,4R)-rel-2,4-Bis(2',4'-difluorophenyl)-2,4-dihydroxypentane; (2R,4R)-2,4-bis(2,4-difluorophenyl)pentane-2,4-diol. CAS No. 1329616-28-5. Molecular formula: C17H16F4O2. Mole weight: 328.3. | |
| ((3R,5R)-5-(2,4-difluorophenyl)-5-(iodomethyl)tetrahydrofuran-3-yl)methanol | ((3R,5R)-5-(2,4-difluorophenyl)-5-(iodomethyl)tetrahydrofuran-3-yl)methanol is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: (3R-cis)-5-(2,4-difluorophenyl)tetrahydro-5-(iodomethyl)-3-furanmethanol. CAS No. 182210-71-5. Molecular formula: C12H13F2IO2. Mole weight: 354.14. | |
| ((3S,5R)-5-(2,4-difluorophenyl)-5-(iodomethyl)tetrahydrofuran-3-yl)methyl isobutyrate | ((3S,5R)-5-(2,4-difluorophenyl)-5-(iodomethyl)tetrahydrofuran-3-yl)methyl isobutyrate is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: [(3S,5R)-5-(2,4-Difluorophenyl)-5-(iodomethyl)tetrahydro-3-furanyl]methyl 2-methylpropionate. CAS No. 1042398-26-4. Molecular formula: C16H19F2IO3. Mole weight: 424.22. | |
| (3S,5S,2S,3R)-Posaconazole | (3S,5S,2S,3R)-Posaconazole is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3R)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one. CAS No. 2243785-98-8. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. | |
| 4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-1-benzyl-1-(4-(1-((2S,3R)-2-hydroxypentan-3-yl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)phenyl)piperazin-1-ium | 4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-1-benzyl-1-(4-(1-((2S,3R)-2-hydroxypentan-3-yl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)phenyl)piperazin-1-ium is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 1819334-66-1. Molecular formula: C57H70F2N10O42. Mole weight: 997.25. | |
| 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one | 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 171228-51-6. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. | |
| 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one | 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 1229428-91-4. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. | |
| 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one | 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 2243785-96-6. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. | |
| 4-(4-(4-(4-(((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one | 4-(4-(4-(4-(((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 213381-06-7. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. | |
| 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one | 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 2243785-99-9. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. | |
| 4-Desfluoro Posaconazole | 4-Desfluoro Posaconazole is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: Desfluoro Posaconazole. Grades: >95%. Molecular formula: C37H43FN8O4. Mole weight: 682.79. | |
| Benzyl (4-(4-(4-Hydroxyphenyl)piperazin-1-yl)phenyl)carbamate | Benzyl (4-(4-(4-Hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic Acid Phenylmethyl Ester. CAS No. 864685-20-1. Molecular formula: C24H25N3O3. Mole weight: 403.47. | |
| Δ24-sterol reductase | Acts on a range of steroids with a 24(25)-double bond, including lanosterol, desmosterol and zymosterol. Group: Enzymes. Synonyms: lanosterol Δ24-reductase. Enzyme Commission Number: EC 1.3.1.72. CAS No. 9033-57-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1341; Δ24-sterol reductase; EC 1.3.1.72; 9033-57-2; lanosterol Δ24-reductase. Cat No: EXWM-1341. | |
| Diniconazole | Diniconazole is a newly developed fungicide strongly inhibited lanosterol 14 alpha-demethylation catalyzed by a yeast cytochrome P-450. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Rac-diniconazole. CAS No. 83657-24-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1948. | |
| Diniconazole | Diniconazol is a chemical compound belonging to chlorine group of conazole. It is used as a fungicide. It inhibited lanosterol 14 alpha-demethylation catalyzed by a yeast cytochrome P-450 strongly. Uses: Pesticide. Synonyms: (E)-(±)-β-[(2,4-Dichlorophenyl)methylene]-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol; (E)-1-(2,4-Dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)-1-penten-3-ol; (E)-β-[(2,4-Dichlorophenyl)methylene]-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol; Mixor; Nb 2; Rac-diniconazole; S 3308; S 3308-10; S 3308L; Spotless; Sumi; Sumi 8; Sumi 8-020FS; Sumi 8-12.5WP; XE 779; 1H-1,2,4-Triazole-1-ethanol, β-[(2,4-dichlorophenyl)methylene]-α-(1,1-dimethylethyl)-, (βE)-. Grades: ≥95%. CAS No. 83657-24-3. Molecular formula: C15H17Cl2N3O. Mole weight: 326.22. | |
| Efinaconazole | Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14α-demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14α-demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following microorganisms, both in vitro and in clinical infections. Efinaconazole exhibits in vitro minimum inhibitory concentrations (MICs) of 0.06 μg/mL or less against most ( ≥ 90%) isolates of the following microorganisms: Trichophyton rubrum; Trichophyton mentagrophytes. Group: Inhibitors. Alternative Names: KP103; KP-103; KP 103; CTK5J2975; AGJ95634; KB145948; Efinaconazole; trade name: Jublia. CAS No. 164650-44-6. Molecular formula: C18H22F2N4O. Mole weight: 348.39. Appearance: Solid powder. Purity: >98%. IUPACName: (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. Canonical SMILES: C[C@@H] (N1CCC (CC1)=C)[C@@] (O) (C2=CC=C (F)C=C2F)CN3N=CN=C3. Catalog: ACM164650446. | |
| Efinaconazole | Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14α-demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14α-demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following microorganisms, both in vitro and in clinical infections. Efinaconazole exhibits in vitro minimum inhibitory concentrations (MICs) of 0.06 μg/mL or less against most ( ≥ 90%) isolates of the following microorganisms: Trichophyton rubrum; Trichophyton mentagrophytes. Synonyms: KP103; KP-103; KP 103; CTK5J2975; AGJ95634; KB145948; AGJ 95634; KB 145948; AGJ-95634; KB-145948; Efinaconazole; trade name: Jublia. Grades: >98%. CAS No. 164650-44-6. Molecular formula: C18H22F2N4O. Mole weight: 348.39. | |
| Ganoderic Acid A | Ganoderic acids are a class of closely related triterpenoids (derivatives from lanosterol) found in Ganoderma mushrooms. For thousands of years, the fruiting bodies of Ganoderma fungi have been used in traditional medicines in East Asia. Consequently, there have been efforts to identify the chemical constituents that may be responsible for the putative pharmacological effects. There are dozens of ganoderic acids that have been isolated and characterized, of which ganoderic acid A and ganoderic acid B are the most well characterized. Some ganoderic acids have been found to possess biological activities including hepatoprotection, anti-tumor effects, and 5-alpha reductase inhibition. (Source: http://en. wikipedia. org/wiki/Ganoderic_acid). Group: Others. Alternative Names: (25R)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanost-8-en-26-oic acid. CAS No. 81907-62-2. Molecular formula: C30H42O7. Mole weight: 514.65. Appearance: Powder. Purity: 0.98. IUPACName: (2R,6R)-6-[(5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid. Canonical SMILES: C[C@H] (CC (=O)C[C@@H] (C)C (=O)O)[C@H]1C[C@@H] ([C@@]2 ([C@@]1 (CC (=O)C3=C2[C@H] (C[C@@H]4[C@@]3 (CCC (=O)C4 (C)C)C)O)C)C)O. Density: 1.22 g/ml. Catalog: ACM81907622. | |
| Itraconazole | Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC 50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase ( cytochrome P450 enzyme ), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein ( OSBP ) inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: R51211. CAS No. 84625-61-6. Pack Sizes: 100 mg; 500 mg. Product ID: HY-17514. | |
| Itraconazole | Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor. Group: Inhibitors. Alternative Names: 3H-1,2,4-Triazol-3-one, 4-(4-(4-(4-((2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-2,4-dihydro-2-(1-methylpropyl)-;(+-)-1-sec-Butyl-4-(p-(4-(p-(((2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup 2)-1,2,4-triazolin-5-one. CAS No. 84625-61-6. Molecular formula: C35H38Cl2N8O4. Mole weight: 705.63. Appearance: Off-white crystalline solid. Purity: 0.9981. Canonical SMILES: ClC1=C (C=CC (Cl) =C1) [C@@]2 (O[C@@H] (COC3=CC=C (N4CCN (C5=CC=C (N (C=NN6C (C) CC) C6=O) C=C5) CC4) C=C3) CO2) CN7C=NC=N7. Density: 1.4 g/cm³. ECNumber: 283-347-2. Catalog: ACM84625616. | |
| Lanopylin A1 | It is produced by the strain of Streptomyces sp. K99-5041. It can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with IC50 of 15 μmol/L. Synonyms: 2-Methyl-3-[(E)-15-methylhexadecane-1-ylidene]-4,5-dihydro-3H-pyrrole. Molecular formula: C22H41N. Mole weight: 319.57. | |
| Lanopylin A2 | It is produced by the strain of Streptomyces sp. K99-5041. It can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with IC50 of 18 μmol/L. Molecular formula: C24H43N. Mole weight: 345.60. | |
| Lanopylin B1 | It is produced by the strain of Streptomyces sp. K99-5041. It can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with IC50 of 33 μmol/L. Synonyms: 2-Methyl-3-[(E)-heptadecane-1-ylidene]-4,5-dihydro-3H-pyrrole. Molecular formula: C22H41N. Mole weight: 319.57. | |
| Lanopylin B2 | It is produced by the strain of Streptomyces sp. K99-5041. It can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with IC50 of 41 μmol/L. Molecular formula: C24H43N. Mole weight: 345.60. | |
| methylsterol monooxygenase | Requires cytochrome b5. Also acts on 4α-methyl-5α-cholest-7-en-3β-ol. The sterol can be based on cycloartenol as well as lanosterol. Group: Enzymes. Synonyms: methylsterol hydroxylase; 4-methylsterol oxidase; 4,4-dimethyl-5α-cholest-7-en-3β-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating). Enzyme Commission Number: EC 1.14.13.72. CAS No. 37256-80-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0879; methylsterol monooxygenase; EC 1.14.13.72; 37256-80-7; methylsterol hydroxylase; 4-methylsterol oxidase; 4,4-dimethyl-5α-cholest-7-en-3β-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating). Cat No: EXWM-0879. | |
| Mineral Oil & Lanolin Alcohol | Enriched blend of natural free alcohols, principally cholesterol, dihydrocholesterol and lanosterol. It is non-toxic and non-irritating to eyes and skin. It serves as a stabilizer for emulsions, dispersions and suspensions and can serve as the primary and/or auxiliary emulsifier for cold creams, cleansing creams and skin lotions. Because of its natural attributes. It serves as an epidermal moisturizer, lubricant and skin emollient. It reduces stickiness without imparting an oily or greasy feel. As an ingredient in moisturizing creams, it imparts dermatological, as well as cosmetic attributes, that provide the moisturizing, lubricating and emollient qualities of lanolin. Uses: Skin and hair care products, color cosmetics. Group: Surfactants/emulsifiers. CAS No. 8012-95-1 / 8020-83-5 / 8042-47-5 / 8027-33-6. Appearance: Yellow to straw colored liquid. Catalog: CI-SC-0303. | |
| N'-((2R,3R)-2-(Benzyloxy)pentan-3-yl)formohydrazide | N'-((2R,3R)-2-(Benzyloxy)pentan-3-yl)formohydrazide is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 2173414-68-9. Molecular formula: C13H20N2O2. Mole weight: 236.31. | |
| O-Benzyl Posaconazole | O-Benzyl Posaconazole is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Uses: Precursor to the fungicide, posaconazole. Synonyms: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-(phenylmethoxy)propyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol; Benzylposaconazole; Posaconazole O-Benzyl Impurity. Grades: >95%. CAS No. 170985-86-1. Molecular formula: C44H48F2N8O4. Mole weight: 790.9. | |
| Posaconazole | Anti-fungal agent; sterol α-demethylase inhibitor. Posaconazole is a highly potent broadspectrum antifungal drug. It blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase resulting in accumulation of methylated sterol precursors. In contrast to other antifungal azoles, posaconazole has been reported not to induce the efflux pump mechanism. Posaconazole was able to produce a parasitological cure in a mouse model of the chronic stage of Chagas disease. Group: Biochemicals. Alternative Names: 2, 5-Anhydro-1, 3, 4-trideoxy-2-C- (2, 4-difluorophenyl) -4- [ [4- [4- [4- [1- [ (1S, 2S) -1-ethyl-2-hydroxypropyl] -1, 5-dihydro-5-oxo-4H-1, 2, 4-triazol-4-yl] phenyl] -1-piperazinyl] phenoxy] methyl] -1- (1H-1, 2, 4-triazol-1-yl) -D-threo-pentitol; Noxafil; Sch 56592. Grades: Highly Purified. CAS No. 171228-49-2. Pack Sizes: 250mg, 500mg, 1g, 5g. Molecular Formula: C??H??F?N?O?, Molecular Weight: 700.78. US Biological Life Sciences. |  Worldwide |
| Posaconazole | Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Uses: For research used only. Synonyms: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol; Noxafil; Sch 56592. Grades: >98%. CAS No. 171228-49-2. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Diastereoisomer 1 | A diastereoisomer of Posaconazole which is an inhibitor of 14-alpha-demethylase and prevents the conversion of lanosterol to ergosterol, an important component of the fungal cell wall. Grades: > 95%. Molecular formula: C37H42F2N8O4. Mole weight: 700.8. | |
| Posaconazole Diastereoisomer 1 (R,R,R,R) | Posaconazole Diastereoisomer 1 (R,R,R,R) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: Posaconazole Impurity 31; all-(R)-Posaconazole; 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3R)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one; (3R,5R,2R,3R)-posaconazole. Grades: 95%. CAS No. 170985-61-2. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Diastereoisomer 2 (R,S,R,R) | Posaconazole Diastereoisomer 2 (R,S,R,R) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: all-(R)-Posaconazole; 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3R)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one. Grades: > 95%. CAS No. 213381-05-6. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Diastereoisomer 3 (S,R,R,R) | Posaconazole Diastereoisomer 3 (S,R,R,R) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(4-(4-(((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. CAS No. 1229428-89-0. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Diastereoisomer 4 (S,S,R,S) | Posaconazole Diastereoisomer 4 (S,S,R,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Diastereoisomer 5 (S,R,R,S) | Posaconazole Diastereoisomer 5 (S,R,R,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: (3R,5S)Posaconazole; 1229428-90-3. Grades: > 95%. CAS No. 1229428-90-3. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Diastereoisomer 6 (R,R,R,S) | Posaconazole Diastereoisomer 6 (R,R,R,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: D-threo-Pentitol, 2,?5-anhydro-1,?3,?4-trideoxy-2-C-(2,?4-difluorophenyl)?-4-[[4-[4-[4-[1-[(1R,?2S)?-1-ethyl-2-hydroxypropyl]?-1,?5-dihydro-5-oxo-4H-1,?2,?4-triazol-4-yl]?phenyl]?-1-piperazinyl]?phenoxy]?methyl]?-1-(1H-1,?2,?4-triazol-1-yl)?-; 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1R,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol. Grades: > 95%. CAS No. 171228-50-5. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Diastereoisomer 7 (R,S,R,S) | Posaconazole Diastereoisomer 7 (R,S,R,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: (3R,5S,2R,3S)-Posaconazole. Grades: > 95%. CAS No. 213381-04-5. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Diastereoisomer 9 (S,S,S,S) | Posaconazole Diastereoisomer 9 (S,S,S,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: all-(S)-Posaconazole; 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. CAS No. 1246391-73-0. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Diastereoisomer Related Compound 1 | Posaconazole Diastereoisomer Related Compound 1 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: (5R-trans)-Toluene-4-sulfonic Acid 5-(2,4-Difluorophenyl)-5-[1,2,4]triazol-1-ylmethyltetrahydrofuran-3-ylmethyl Ester; 1,4-Anhydro-2,3,5-trideoxy-4-C-(2,4-difluorophenyl)-2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-5-(1H-1,2,4-triazol-1-yl)-D-erythro-pentitol. Grades: > 95%. CAS No. 159811-30-0. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47. | |
| Posaconazole Diastereoisomer Related Compound 2 | Posaconazole Diastereoisomer Related Compound 2 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-erythro-pentitol; D-erythro-Pentitol, 2, ?5-anhydro-1, ?3, ?4-trideoxy-2-C- (2, ?4-difluorophenyl) ?-4-[[[ (4-methylphenyl) ?sulfonyl]?oxy]?methyl]?-1- (1H-1, ?2, ?4-triazol-1-yl) ?-. Grades: > 95%. CAS No. 166583-12-6. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47. | |
| Posaconazole Diastereoisomer Related Compound 3 | Posaconazole Diastereoisomer Related Compound 3 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 2-((2R,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. CAS No. 2185472-85-7. Molecular formula: C30H35N5O3. Mole weight: 513.63. | |
| Posaconazole Diastereoisomer Related Compound 4 | Posaconazole Diastereoisomer Related Compound 4 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 2-((2S,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. CAS No. 2125944-53-6. Molecular formula: C30H35N5O3. Mole weight: 513.63. | |
| Posaconazole Diastereoisomer Related Compound 5 | Posaconazole Diastereoisomer Related Compound 5 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-L-threo-pentitol. Grades: > 95%. CAS No. 149809-42-7. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47. | |
| Posaconazole Diastereoisomer (R,R,S,S) | Posaconazole Diastereoisomer (R,R,S,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(4-(4-(((3R,5R)-5-((4H-1,2,4-Triazol-4-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one; (1,2,4-Triazol-4-yl) Posaconazole. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Diastereoisomer (S,R,S,S) | Posaconazole Diastereoisomer (S,R,S,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: (3S,5R,2S,3S)-Posaconazole. Grades: 95%. CAS No. 213381-02-3. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Enantiomer | Posaconazole Enantiomer is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: ent-Posaconazole. Grades: > 95%. CAS No. 2243785-97-7. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole hydrate | Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole strongly inhibits 14-alpha demethylase, a cytochrome P450-dependent enzyme. Posaconazole is a sterol C14? demethylase inhibitor with an IC50 of 0.25 nM. Inhibition of 14-alpha-demethylase prevents the conversion of lanosterol to ergosterol, an important component of the fungal cell wall. Inhibition of ergosterol synthesis changes the fungal cell membrane composition and integrity, alters membrane permeability and eventually leads to fungal cell lysis. Compared to other azole antifungals, posaconazole is a significantly more potent inhibitor of sterol 14-alpha demethylase. Posaconazole is the most advanced candidate for the treatment of Chagas disease. Posaconazole has entered in a phase II clinical trial in the treatment of mycoses. Synonyms: SCH56592 hydrate; SCH-56592 hydrate; SCH 56592 hydrate. Grades: >98%. CAS No. 1198769-38-8. Molecular formula: C37H44F2N8O5. Mole weight: 718.79. | |
| Posaconazole Impurity 1 | Posaconazole Impurity 1 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: Posaconazole Imidazolidine Impurity; 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[3-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-imidazolidinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol. Grades: > 95%. CAS No. 1388148-29-5. Molecular formula: C36H40F2N8O4. Mole weight: 686.75. | |
| Posaconazole Impurity 10 (POS-A) | Posaconazole Impurity 10 (POS-A) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((R)-2-oxopentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. Molecular formula: C37H40F2N8O4. Mole weight: 698.76. | |
| Posaconazole Impurity 11 (POS-B) | Posaconazole Impurity 11 (POS-B) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)-3-(4-(4-(4-(1-((2S,3R)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazin-1-yl)phenoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. Molecular formula: C60H69F2N13O7. Mole weight: 1122.27. | |
| Posaconazole Impurity 12 (POS-G) | Posaconazole Impurity 12 (POS-G) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. Molecular formula: C37H40F2N8O5. Mole weight: 714.76. | |
| Posaconazole Impurity 13 (POS-H) | Posaconazole Impurity 13 (POS-H) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. Molecular formula: C37H40F2N8O6. Mole weight: 730.76. | |
| Posaconazole Impurity 14 (POS-I) | Posaconazole Impurity 14 (POS-I) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. Molecular formula: C36H40F2N8O5. Mole weight: 702.75. | |
| Posaconazole Impurity 15 | Posaconazole Impurity 15 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. Molecular formula: C20H18ClF2N3O4S. Mole weight: 469.89. | |
| Posaconazole Impurity 16 | Posaconazole Impurity 16 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: ((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-chlorobenzenesulfonate; D-erythro-Pentitol, 1,4-anhydro-2-[[[(4-chlorophenyl)sulfonyl]oxy]methyl]-2,3,5-trideoxy-4-C-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)-; 1,4-Anhydro-2-({[(4-chlorophenyl)sulfonyl]oxy}methyl)-2,3,5-trideoxy-4-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)-D-erythro-pentitol; Posaconazole Intermediate (R-trans isomer). Grades: ≥95%. CAS No. 2243786-07-2. Molecular formula: C20H18ClF2N3O4S. Mole weight: 469.89. | |
| Posaconazole Impurity 17 | Posaconazole Impurity 17 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: ((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methanol. Grades: > 95%. CAS No. 149882-18-8. Molecular formula: C14H15F2N3O2. Mole weight: 295.28. | |
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