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10mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C26H40O5. CAS No. 130209-82-4. Prepack ID 89170770-10mg. Molecular Weight 432.59. See USA prepack pricing.
Latanoprost
Latanoprost eye solution is a medication administered into the eyes to control the progression of glaucoma or ocular hypertension by reducing intraocular pressure (IOP). It is a prostaglandin analogue (more specifically an analogue of prostaglandin F2α) that lowers the pressure by increasing the outflow of aqueous fluid from the eyes through the uveoscleral tract. Latanoprost is an isopropyl ester prodrug, meaning it is inactive until it is hydrolyzed by esterases in the cornea to the biologically active acid.Latanoprost was invented by Johan W. Stjernschantz and Bahram Resul, employees of the Pharmacia Corporation of Uppsala, Sweden. It is on the World Health Organizations List of Essential Medicines, a list of the most important medication needed in a basic health system. It is also known by the brand name of Xalatan manufactured by Pfizer. Annual sales are approximately $1.6 billion. The patent for latanoprost expired in March 2011, and at least one generic version is now widely available in the U.S. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Isopropyl (5Z,9Α,11Α,15R)-9,11,15-Trihydroxy-17-Phenyl-18,19,20-Trinor-Prost-5-En-1-Oate. Appearance: Oil. CAS No. 130209-82-4. Molecular formula: C26H40O5. Mole weight: 432.59. Purity: 0.98. Canonical SMILES: CC(C)OC(=O)CCC/C=C\\C[C@H]1[C@H](C[C@H]([C@@H]1CC[C@H](CCC2=CC=CC=C2)O)O)O. Density: 1.093 g/cm³. Product I
Latanoprost
Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2α (17-phenyl-13,14-dihydro PGF2α). It is a prodrug form of the free acid, which is a potent agonist of the FP receptor in the eye. Latanoprost reduces intraocular pressure in glaucoma patients with few side effects. The EC50 value of latanoprost (tested as the free acid) for FP receptors is 3.6 nM. Synonyms: PHXA41; PHXA-41; PHXA 41; XA34; XA-34; XA 34; Latanoprost, Xalatan, Catioprost. Grades: >98%. CAS No. 130209-82-4. Molecular formula: C26H40O5. Mole weight: 432.59.
Latanoprost
Latanoprost (PHXA41) is a prostaglandin F2α analogue and can be used for glaucoma research. Latanoprost can effectively pass through cornea and be hydrolyzed by esterase to latanoprost acid. latanoprost acid is an F-prostaglandin (FP) receptor agonist, and can effectively reduce intraocular pressure (IOP) by increasing the outflow of aqueous humor through uvea [1]. Uses: Scientific research. Group: Natural products. Alternative Names: PHXA41. CAS No. 130209-82-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0577.
Latanoprost
Prostaglandin analog, used to treat glaucoma and other degenerative diseases of the eye. Group: Biochemicals. Alternative Names: (5Z) -7- [ (1R, 2R, 3R, 5S) -3, 5-Dihydroxy-2- [ (3R) -3-hydroxy-5-phenylpentyl] cyclopentyl] -5-heptenoic Acid 1-Methylethyl Ester; Isopropyl- (Z) -7- [ (1R, 2R, 3R, 5S) -3, 5-dihydroxy-2- [ (3R) -3-hydroxy-5-phenylpentyl] cyclopentyl] -5-heptenoate; PhXA-41; GAAP Ofteno; Xalatan; (15R)-Latanoprost. Grades: Highly Purified. CAS No. 130209-82-4. Pack Sizes: 10mg, 25mg. Molecular Formula: C??H??O?, Molecular Weight: 432.59. US Biological Life Sciences.
(5Z,9α,11α,15R)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinorprost-5-en-1-oic acid. PDE5 inhibitor for erectile dysfunction A semisynthetic ansamycin antibiotic, cyclopentyl derivative of Rifamycin. Treatment of pulmonary tuberculosis. CAS No. 41639-83-2. Product ID: 8-01797. Molecular formula: C23H35O5. Mole weight: 390.51. Purity: 0.98. Source :
Latanoprost Acid
A metabolite of Latanoprost. Potent, selective FP prostanoid receptor agonist. F-series Prostaglandin analog. 200 times as potent as isopropyl ester form. Latanoprost USP Related Compound E. Group: Biochemicals. Alternative Names: (5Z) -7- [ (1R, 2R, 3R, 5S) -3, 5-Dihydroxy-2- [ (3R) -3-hydroxy-5-phenylpentyl] cyclopentyl] -5-heptenoic Acid; 13,14-Dihydro-17-phenyl-18,19,20-trinor-PGF2α; PhXA 85; Latanoprost USP Related Compound E. Grades: Highly Purified. CAS No. 41639-83-2. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??O?, Molecular Weight: 390.51. US Biological Life Sciences.
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Latanoprost Acid
A metabolite of Latanoprost. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid. Grades: > 95%. CAS No. 41639-83-2. Molecular formula: C23H34O5. Mole weight: 390.52.
Latanoprost-d4
Latanoprost-d4 is the labeled analogue of Latanoprost (L177280), a Prostaglandin analog, used to treat glaucoma and other degenerative diseases of the eye. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C26H36D4O5, Molecular Weight: 436.62. US Biological Life Sciences.
Worldwide
Latanoprostene bunod
Latanoprostene bunod (LBN), a nitric oxide (NO)-donating prostaglandin F2a analog, is a topical ophthalmic therapeutic for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NCX116; LBN. CAS No. 860005-21-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-19518.
Latanoprostene Bunod
Latanoproste bunod is a nitric oxide-donating prostaglandin F2α (FP) receptor agonist. Under the trade name Vyzulta, it has been approved for the treatment of intraocular pressure in patients with open-angle glaucoma or ocular hypertension in 2017. Synonyms: BOL-303259-X; NCX 116; PF-3187207. Grades: ≥95%. CAS No. 860005-21-6. Molecular formula: C27H41NO8. Mole weight: 507.62.
Latanoprost EP Impurity D
Latanoprost EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2088449-88-9. Molecular Formula: C20H25O3P. Mole Weight: 344.39. Catalog: APB2088449889.
Latanoprost EP Impurity F
Latanoprost EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 913258-34-1. Molecular Formula: C26H40O5. Mole Weight: 432.6. Catalog: APB913258341.
15-Keto latanoprost. Group: Biochemicals. Alternative Names: (5Z) -7-[ (1R, 2R, 3R, 5S) -3, 5-Dihydroxy-2- (3-oxo-5-phenylpentyl) cyclopentyl]-5-heptenoic acid 1-methylethyl ester. Grades: Highly Purified. CAS No. 135646-98-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C26H38O5. US Biological Life Sciences.
Worldwide
15-Keto Latanoprost
a metabolite of Latanoprost. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; [1R-[1α(Z), 2β, 3α, 5α]]-7-[3, 5-Dihydroxy-2-(3-oxo- 5-phenylpentyl)cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester. Grades: > 95%. CAS No. 135646-98-9. Molecular formula: C26H38O5. Mole weight: 430.59.
15-Keto Latanoprost Acid
a potential metabolite of latanoprost when administered to animals. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-5-heptenoic Acid. Grades: > 95%. CAS No. 369585-22-8. Molecular formula: C23H32O5. Mole weight: 388.51.
15(R)-trans-Latanoprost (10.0 mg in 1.0 ml methyl acetate)
An impurity of Latanoprost, a medication used to treat glaucoma and ocular hypertension. Synonyms: (15S)-Latanoprost; Latanoprost USP Related Compound B. Grades: > 95%. CAS No. 145773-22-4. Molecular formula: C26H40O5. Mole weight: 432.61.
(15S)-Latanoprost acid
(15S)-Latanoprost acid. Group: Biochemicals. Alternative Names: [1R-[1a (Z) , 2b (S*) , 3a, 5a]]-7-[3, 5-Dihydroxy-2- (3-hydroxy-5-phenylpentyl) cyclopentyl]-5-heptenoic acid; 15-epi-latanoprost acid. Grades: Highly Purified. CAS No. 41639-84-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C23H34O5. US Biological Life Sciences.
an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Synonyms: (5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester. Grades: > 95%. CAS No. 913258-34-1. Molecular formula: C26H40O5. Mole weight: 432.60.
5-Trans latanoprost
Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Grades: ≥98%. CAS No. 903549-49-5. Molecular formula: C23H34O5. Mole weight: 390.5.
9-Acetyl Latanoprost
An analog of Latanoprost, a prostaglandin analog, used to treat glaucoma and other degenerative diseases of the eye. Grades: > 95%. Molecular formula: C28H42O6. Mole weight: 474.64.
Prostaglandin analog; prodrug of active acid metabolite. It is a synthetic derivative of the natural prostaglandin PGF2α, used as an anti-glaucoma agent that is effective in various types of glaucoma and ocular hypertension. Group: Biochemicals. Alternative Names: (5E) -7- [ (1R, 2R, 3R, 5S) -3, 5-Dihydroxy-2- [ (3R) -3-hydroxy-5-phenylpentyl] cyclopentyl] -5-heptenoic Acid 1-Methylethyl Ester; (5E)-Latanoprost; 5,6-trans-Latanoprost. Grades: Highly Purified. CAS No. 913258-34-1. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
Worldwide
trans-Latanoprost acid
trans-Latanoprost acid. Group: Biochemicals. Alternative Names: (5E) -7- [ (1R, 2R, 3R, 5S) -3, 5-Dihydroxy-2- [ (3R) -3-hydroxy-5-phenylpentyl] cyclopentyl] -5-heptenoic acid. Grades: Highly Purified. CAS No. 903549-49-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C23H34O5. US Biological Life Sciences.
[1,1'-Biphenyl]-4-carboxylic Acid (3aR,4R,5R,6aS)-Hexahydro-2-oxo-4-[(1E)-3-oxo-5-phenyl-1-penten-1-yl]-2H-cyclopenta[b]furan-5-yl ester is an intermediate in the synthesis of Latanoprost (L177280) related analogues used in the treatment of glaucoma and various degenerative eye diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 41639-72-9. Pack Sizes: 50mg, 250mg. Molecular Formula: C31H28O5. US Biological Life Sciences.
[1,1'-Biphenyl]-4-carboxylic Acid (3aR,4R,5R,6aS)-Hexahydro-4-[(3R)-3-hydroxy-5-phenylpentyl]-2-oxo-2H-cyclopenta[b]furan-5-yl Ester is an intermediate in the synthesis of Latanoprost (L177280) related analogues used in the treatment of glaucoma and various degenerative eye diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 145667-74-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C31H32O5. US Biological Life Sciences.
Worldwide
13,14-Dihydro Bimatoprost
13,14-Dihydro Bimatoprost is an impurity of Bimatoprost, which is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethyl-5-heptenamide; N-Ethyl-9-alpha,11-alpha,15R-trihydroxy-17-phenyl-18,19,20-trinor-prost-5Z-en-1-amide; Latanoprost ethyl amide; LAT-NET. Grades: 98%. CAS No. 607351-44-0. Molecular formula: C25H39NO4. Mole weight: 417.58.
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 value for the free acid forms of 15(R)-17-phenyl trinor PGF2α wa determined to be 30 nM in a FP receptor binding assay using the cat iris sphincter muscle. Synonyms: 9α,11α,15R-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester; 15-epi Bimatoprost isopropylester; 15(R)-Bimatoprost isopropyl ester; 15(R)-17-phenyl trinor PGF2α isopropyl ester; Isopropyl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-5-heptenoate; 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-. Grades: 98%. CAS No. 130273-87-9. Molecular formula: C26H38O5. Mole weight: 430.59.
17-Phenyl trinor PGF2α isopropyl ester
17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost.1 The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost.2 This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist.3 In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. The 17-phenyl trinor PGF2α isopropyl ester derivative is examined for IOP-lowering activity during the development of latanoprost.4 At the dose of 3 μg/eye in the monkey, 17-phenyl trinor PGF2α isopropyl ester is the most potent analog tested in reducing IOP, lowering the IOP 1.3 mm Hg below the level achieved by latanoprost. However, this derivative is also significantly more irritating to the eye than latanoprost. Uses: Scientific research. Group: Signaling pathways. CAS No. 130209-76-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116161A.
[1R-[1α(Z),2 β, 3α, 5α]]-7-[3, 5-Dihydroxy-2-[2-[2-(2-phenylethyl)-1, 3-dioxolan-2-yl]ethyl]cyclopentyl]-5-heptenoic Acid is an intermediate in the synthesis of 15-Keto Latanoprost (K195350). 15-Keto Latanoprost is a metabolite of Latanoprost (L177280). Group: Biochemicals. Grades: Highly Purified. CAS No. 59619-40-8. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C25H36O6, Molecular Weight: 432.55. US Biological Life Sciences.
(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Synonyms: 2H-Cyclopenta[b]furan-2,5-diol, hexahydro-4-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]-, (3aR,4R,5R,6aS)-(9CI); (3aR,4R,5R,6aS)-Hexahydro-4-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-2H-cyclopenta[b]furan-2,5-diol; Bimatoprost intermediates; Latanoprost intermediates. Grades: 98%. CAS No. 856240-62-5. Molecular formula: C18H24O4. Mole weight: 304.38.
5-Heptenoicacid,7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-,1-methylethyl ester,(5E)-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (5E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester;(5E)-Latanoprost;5,6-trans-Latanoprost;trans Latanoprost. Product Category: Heterocyclic Organic Compound. Appearance: Colourless Oil. CAS No. 913258-34-1. Molecular formula: C26H40O5. Product ID: ACM913258341. Alfa Chemistry ISO 9001:2015 Certified.
ACS 67
ACS 67 is an analog of latanoprost that contains a hydrogen sulfide releasing component conjugated to the latanoprost carboxyl group. Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug for the treatment of glaucoma. Synonyms: [4-(5-sulfanylidenedithiol-3-yl)phenyl] (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate. Grades: ≥95%. CAS No. 1088434-86-9. Molecular formula: C32H38O5S3. Mole weight: 598.8.
AL 8810 isopropyl ester
AL 8810 is a prostaglandin F2a analog and a selective FP prostanoid receptor antagonist. AL 8810 isopropyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as Latanoprost and Travoprost. Synonyms: AL 8810 isopropyl ester; Propan-2-yl (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoate; 5-Heptenoic acid, 7-[(1R,2R,3S,5S)-2-[(1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl]-3-fluoro-5-hydroxycyclopentyl]-, 1-methylethyl ester, (5Z)-; HMS3648C21; AKOS025294879; SR-01000946200; SR-01000946200-1; 9alpha, 15R- dihydroxy- 11beta- fluoro- 15- (2, 3- dihydro- 1H- inden- 2- yl)- 16, 17, 18, 19, 20- pentanor- prosta- 5Z, 13E- dien- 1- oic acid, isopropyl ester. Grades: ≥98%. CAS No. 208114-93-6. Molecular formula: C27H37FO4. Mole weight: 444.6.
AL 8810 methyl ester
AL 8810 is a prostaglandin F2a analog and a selective FP prostanoid receptor antagonist. AL 8810 methyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as Latanoprost and Travoprost. Synonyms: AL 8810 methyl ester; 1176541-11-9; methyl (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoate; CHEBI:186084; DTXSID001347566; methyl (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-luoro-5-hydroxycyclopentyl]hept-5-enoate. Grades: ≥98%. CAS No. 1176541-11-9. Molecular formula: C25H33FO4. Mole weight: 416.5.
Diphenylphosphine isopropyl ester
Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2&alpha. Diphenylphosphine isopropyl ester is a potential trace impurity in commercial preparations of latanoprost. Synonyms: DPP isopropyl ester. Grades: ≥98%. Molecular formula: C20H25O3P. Mole weight: 344.4.
Misoprostol
Methyl 7-{3-hydroxy-2-[(E)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl}heptanoate. selective FP prostanoid receptor agonist, F-series prostaglandin analog. 200 times as potent as Latanoprost -20ºC. CAS No. 59122-46-2. Product ID: 8-01794. Molecular formula: C22H38O5. Mole weight: 382.5. Source : Reference: Exp. Eye Res. 74, 41-49, 2002.
Polyquaternium 1
Polyquaternium 1 is an antimicrobial preservative used for rabbit ocular surface study on polyquad-preserved travoprost/timolol, benzalkonium chloride-preserved travoprost/timolol, and latanoprost/timolol in fixed combinations. Group: Biochemicals. Alternative Names: α -[4-[Tris (2-hydroxyethyl) ammonio]-2-buten-1-yl]-ω -[tris (2-hydroxyethyl) ammonio]poly[ (dimethyliminio) -2-butene-1, 4-diyl Chloride] Chloride; Onamer M; Onyxsperse 12S; Polidronium Chloride; Polyquad; Polyquat 1. Grades: Highly Purified. CAS No. 75345-27-6. Pack Sizes: 100mg, 500mg, 1g. Molecular Formula: (C?H??ClN)n C??H??Cl?N?O?, Molecular Weight: ~2500. US Biological Life Sciences.
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Polyquaternium 1, 0.38% Sterile Liquid
Polyquaternium 1 is an antimicrobial preservative used for rabbit ocular surface study on polyquad-preserved travoprost/timolol, benzalkonium chloride-preserved travoprost/timolol, and latanoprost/timolol in fixed combinations. Group: Biochemicals. Alternative Names: α -[4-[Tris (2-hydroxyethyl) ammonio]-2-buten-1-yl]-ω -[tris (2-hydroxyethyl) ammonio]poly[ (dimethyliminio) -2-butene-1, 4-diyl Chloride] Chloride; Onamer M; Onyxsperse 12S; Polidronium Chloride; Polyquad; Polyquat 1. Grades: Highly Purified. CAS No. 75345-27-6. Pack Sizes: 10ml, 25ml, 100ml. Molecular Formula: (C?H??ClN)n C??H??Cl?N?O?, Molecular Weight: ~2500. US Biological Life Sciences.