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3-(4-Amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dione. antitussive. CAS No. 191732-72-6. Product ID: 8-01777. Molecular formula: C13H13N3O3. Mole weight: 259.26. Reference: Bull World Health Org 72: 729-35.1994 Pharmacol Biochem Behav 67, 37-44, 2000 Trans R Soc Trop Med Hyg Z 101.
Lenalidomide
Cereblon binder; induces ubiquitination and degradation of CK1a and transcription factors IKZF1, IKZF3 and SALL4 by E3 ubiquitin ligase. Synonyms: CC5013; CC-5013; CC 5013; IMiD1; Lenalidomide; US brand name: Revlimid. Grades: ≥98% (HPLC). CAS No. 191732-72-6. Molecular formula: C13H13N3O3. Mole weight: 259.26.
Lenalidomide
Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-5013. CAS No. 191732-72-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-A0003.
Lenalidomide
Lenalidomide is an immunomodulatory drug; analog of Thalidomide. Group: Biochemicals. Alternative Names: 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione; 1-Oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline; CC-5013. Grades: Highly Purified. CAS No. 191732-72-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Lenalidomide-F
Lenalidomide-F is a E3 ligase ligand for LWY713. LWY713 is a PROTAC-class FLT3 degrader (DC 50 = 0.64 nM), which selectively induces FLT3 degradation via cereblon and proteasome-dependent pathways [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2359705-88-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W039233.
Lenalidomide hemihydrate
Lenalidomide hemihydrate (CC-5013 hemihydrate) is a derivative of Thalidomide and functions as an orally active immunomodulator. It acts through cereblon-mediated selective ubiquitination and degradation of IKZF1 and IKZF3 lymphocyte transcription factors, inhibiting the growth of mature B-cell lymphomas including multiple myeloma, and inducing interleukin-2 (IL-2) release from T cells. Synonyms: Revlimid hemihydrate; CC-5013 hemihydrate. Grades: >98%. CAS No. 847871-99-2. Molecular formula: C26H28N6O7. Mole weight: 268.27.
Lenalidomide hydrochloride
Lenalidomide hydrochloride (CC-5013 hydrochloride) is a derivative of Thalidomide and functions as an orally active immunomodulator. It acts through cereblon-mediated selective ubiquitination and degradation of IKZF1 and IKZF3 lymphocyte transcription factors, inhibiting the growth of mature B-cell lymphomas including multiple myeloma, and inducing interleukin-2 (IL-2) release from T cells. Synonyms: Revlimid hydrochloride; CC-5013 hydrochloride; CC5013 hydrochloride; CC 5013 hydrochloride. Grades: >98%. CAS No. 1243329-97-6. Molecular formula: C13H14ClN3O3. Mole weight: 295.72.
Lenalidomide-I
Lenalidomide-I (Compound 72), an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, is used in the recruitment of CRBN protein. Lenalidomide-I can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC BET degrader QCA570 (HY-112609) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2207541-30-6. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-131318.
Lenalidomide Impurity 1
Lenalidomide Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C13H11N3O4. Mole Weight: 273.25. Catalog: APB08385.
Lenalidomide Impurity 10
Lenalidomide Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-amino-4-(4-amino-1-oxoisoindolin-2-yl)-5-oxopentanoic acid. CAS No. 2197414-57-4. Molecular Formula: C13H15N3O4. Mole Weight: 277.28. Catalog: APB2197414574.
Lenalidomide Impurity 11
Lenalidomide Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 48103-74-8. Molecular Formula: C5H7NO3. Mole Weight: 129.11. Catalog: APB48103748.
Lenalidomide Impurity 12
Lenalidomide Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 295357-72-1. Molecular Formula: C13H12N2O7. Mole Weight: 308.25. Catalog: APB295357721.
Lenalidomide Impurity 13
Lenalidomide Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 874760-71-1. Molecular Formula: C13H13N3O6. Mole Weight: 307.26. Catalog: APB874760711.
Lenalidomide Impurity 16
Lenalidomide Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133446-99-8. Molecular Formula: C9H8BrNO4. Mole Weight: 274.07. Catalog: APB133446998.
Lenalidomide Impurity 17
Lenalidomide Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 90725-68-1. Molecular Formula: C9H8BrNO4. Mole Weight: 274.07. Catalog: APB90725681.
Lenalidomide Impurity 18
Lenalidomide Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 61940-21-4. Molecular Formula: C9H8BrNO4. Mole Weight: 274.07. Catalog: APB61940214.
Lenalidomide Impurity 19
Lenalidomide Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1421593-80-7. Molecular Formula: C15H15N3O4. Mole Weight: 301.3. Catalog: APB1421593807.
Lenalidomide Impurity 2
Lenalidomide Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2717380-87-3. Molecular Formula: C13H13N3O4. Mole Weight: 275.26. Catalog: APB2717380873.
Lenalidomide Impurity 21
Lenalidomide Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2089206-55-1. Molecular Formula: C14H17N3O4. Mole Weight: 291.31. Catalog: APB2089206551.
Lenalidomide Impurity 23
Lenalidomide Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 6810-78-2. Molecular Formula: C5H7NO3. Mole Weight: 129.12. Catalog: APB6810782.
Lenalidomide Impurity 24
Lenalidomide Impurity 24. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(4-amino-1-oxoisoindolin-2-yl)-5-methoxy-5-oxopentanoic acid. Molecular Formula: C14H16N2O5. Mole Weight: 292.29. Catalog: APB01598.
Lenalidomide Impurity 27
Lenalidomide Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18583-89-6. Molecular Formula: C9H11NO2. Mole Weight: 165.19. Catalog: APB18583896.
Lenalidomide Impurity 4
Lenalidomide Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(4-amino-1-oxoisoindolin-2-yl)pentanediamide. Molecular Formula: C13H16N4O3. Mole Weight: 276.29. Catalog: APB01599.
Lenalidomide Impurity 41
Lenalidomide Impurity 41. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1975-51-5. Molecular Formula: C8H7NO4. Mole Weight: 181.15. Catalog: APB1975515.
Lenalidomide Impurity 42
Lenalidomide Impurity 42. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1975-50-4. Molecular Formula: C8H7NO4. Mole Weight: 181.15. Catalog: APB1975504.
Lenalidomide Impurity 43
Lenalidomide Impurity 43. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2197414-56-3. Molecular Formula: C14H13N3O4. Mole Weight: 287.27. Catalog: APB2197414563.
Lenalidomide Impurity 44
Lenalidomide Impurity 44. Uses: For analytical and research use. Group: Impurity standards. CAS No. 290366-59-5. Molecular Formula: C8H8N2O3. Mole Weight: 180.16. Catalog: APB290366595.
Lenalidomide Impurity 45
Lenalidomide Impurity 45. Uses: For analytical and research use. Group: Impurity standards. CAS No. 99584-16-4. Molecular Formula: C8H8N2O3. Mole Weight: 180.16. Catalog: APB99584164.
Lenalidomide Impurity 46
Lenalidomide Impurity 46. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H22ClN5O5. Mole Weight: 423.85. Catalog: APB08386.
Lenalidomide Impurity 47
Lenalidomide Impurity 47. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1630974-89-8. Molecular Formula: C9H7Br2NO4. Mole Weight: 352.97. Catalog: APB1630974898.
Lenalidomide Impurity 48
Lenalidomide Impurity 48. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1063995-41-4. Molecular Formula: C17H22N2O5. Mole Weight: 334.37. Catalog: APB1063995414.
Lenalidomide Impurity 49
Lenalidomide Impurity 49. Uses: For analytical and research use. Group: Impurity standards. CAS No. 88071-90-3. Molecular Formula: C9H8BrNO4. Mole Weight: 274.07. Catalog: APB88071903.
Lenalidomide Impurity 5
Lenalidomide Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(4-amino-1-oxoisoindolin-2-yl)pentanedioic acid. CAS No. 295357-66-3. Molecular Formula: C13H14N2O5. Mole Weight: 278.26. Catalog: APB295357663.
Lenalidomide Impurity 50
Lenalidomide Impurity 50. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132874-06-7. Molecular Formula: C9H8BrNO4. Mole Weight: 274.07. Catalog: APB132874067.
Lenalidomide Impurity 51
Lenalidomide Impurity 51. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H19N3O4. Mole Weight: 305.33. Catalog: APB08388.
Lenalidomide Impurity 52
Lenalidomide Impurity 52. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H19N3O4. Mole Weight: 305.33. Catalog: APB08387.
Lenalidomide Impurity 55
Lenalidomide Impurity 55. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2197420-75-8. Molecular Formula: C13H15N3O4. Mole Weight: 277.28. Catalog: APB2197420758.
Lenalidomide Impurity B
An impurity of Lenalidomide, a medication used for the treatment of myelodysplastic syndrome (MDS), multiple myeloma, and mantle cell lymphoma (MCL). Synonyms: 3-(1,3-Dihydro-4-nitro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione; 3-(4-Nitro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione; 4-Nitro Lenalidomide. Grades: > 95%. CAS No. 827026-45-9. Molecular formula: C13H11N3O5. Mole weight: 289.25.
Lenalidomide Lactosamine Adduct
Lenalidomide Lactosamine Adduct is a derivative of Lenalidomide (L328000), an oral immunomodulatory agent for the management of myelodysplastic syndromes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C25H33N3O13. US Biological Life Sciences.
Worldwide
Lenalidomide N(imido)-Glucoside
Lenalidomide N(imido)-Glucoside is a derivative of Lenalidomide; an immunomodulatory drug and analog of Thalidomide. Synonyms: 3-(4-Amino-1-oxoisoindolin-2-yl)-1-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)piperidine-2,6-dione. Molecular formula: C19H23N3O8. Mole weight: 421.4.
Lenalidomide (Standard)
Lenalidomide (Standard) is the analytical standard of Lenalidomide. This product is intended for research and analytical applications. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191732-72-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0003R.
4-Nitro lenalidomide
4-Nitro lenalidomide. Group: Biochemicals. Alternative Names: 3-(1,3-Dihydro-4-nitro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione; 3-(4-Nitro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione; 3-(4-Nitro-1-oxo-1,3-dihydroisoindol-2-yl)piperidine-2,6-dione. Grades: Highly Purified. CAS No. 827026-45-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C13H11N3O5. US Biological Life Sciences.
Worldwide
N-Methyl Lenalidomide
N-Methyl Lenalidomide. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS010634. Format: Neat. Shipping: Room Temperature.
rac Lenalidomide-13C5
Labeled Lenalidomide. Immunomodulatory drug; analog of Thalidomide. Group: Biochemicals. Alternative Names: 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione-13C5; 1-Oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline-13C5; CC-5013-13C5. Grades: Highly Purified. CAS No. 1219332-91-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
(R,S)-Lenalidomide, Free Base (3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione, CC-5013, CDC-501, ENMD-0997, Revamid, Revimid)
Cell-permeable. An analog of thalidomide that was originally found based on its ability to effectively inhibit tumor necrosis factor production. Lenalidomide is 50,000 times more potent than thalidomide in inhibiting Tumor Necrosis Factor-a (TNF-a). Displays potent anti-tumor and anti-inflammatory effects as well as modulates and potentiates host immune responses against multiple myeloma. Group: Biochemicals. Grades: Highly Purified. CAS No. 191732-72-6. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
2-(4-Amino-1-oxoisoindolin-2-yl)pentanediamide
2-(4-Amino-1-oxoisoindolin-2-yl)pentanediamide is an impurity of Lenalidomide (L328000), an immunomodulatory drug; analog of Thalidomide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. Molecular Formula: C13H16N4O3, Molecular Weight: 276.29. US Biological Life Sciences.
Worldwide
2-(4-Nitro-1-oxoisoindolin-2-yl)pentanedioic Acid
2-(4-Nitro-1-oxoisoindolin-2-yl)pentanedioic Acid is an impurity of Lenalidomide (L328000), an immunomodulatory drug; analog of Thalidomide. Group: Biochemicals. Grades: Highly Purified. CAS No. 295357-72-1. Pack Sizes: 10mg, 50mg. Molecular Formula: C13H12N2O7, Molecular Weight: 308.24. US Biological Life Sciences.
2-(Hydroxymethyl)-3-nitrobenzoic Acid Methyl Ester is used in the synthesis of Lenalidomide (L328000) and its intermediates. Group: Biochemicals. Grades: Highly Purified. CAS No. 1628915-10-5. Pack Sizes: 5mg, 10mg. Molecular Formula: C9H9NO5, Molecular Weight: 211.17. US Biological Life Sciences.
3-(4-Amino-1,3-dihydro-5-hydroxy-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione is a related compound of Lenalidomide (L328000), an immunomodulatory drug and an analog of Thalidomide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1421593-78-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C13H13N3O4, Molecular Weight: 275.26. US Biological Life Sciences.
3-(4-fluoro-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Lenalidomide-F. Product Category: E3 Ligase Ligand. CAS No. 2359705-88-5. Molecular formula: C13H11FN2O3. Mole weight: 262.2365. Purity: 0.95. IUPACName: 3-(7-fluoro-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione. Product ID: PR2359705885. Alfa Chemistry ISO 9001:2015 Certified. Categories: 3-(4-Fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione.
3-(5-bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Lenalidomide-5-Br. Product Category: PROTAC Library. CAS No. 1010100-26-1. Molecular formula: C13H11BrN2O3. Mole weight: 323.142. Purity: 0.96. IUPACName: 3-(6-bromo-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione. Product ID: PR1010100261. Alfa Chemistry ISO 9001:2015 Certified.
3-amino-2,6-piperidinedione hydrochloride
3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del(5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. Synonyms: 3-Amino-2,6-piperidinedione Monohydrochloride; 2-Amino-glutarimide Hydrochloride; 3-Amino-2,6-dioxopiperidine Hydrochloride; 3-Aminopiperidine-2,6-dione Monohydrochloride; DL-Glutamic Acid Imide Hydrochloride; Glutamimide Hydrochloride; 2,6-dioxopiperidine-3-ammonium chloride; Glutamic acid imide hydrochloride; Glutamic acid imide-DL-hydrochloride; ACMC-20a23n; (+-)-3-Amino-2,6-piperidinedione monohydrochloride; AMPD00004; 3-Aminopiperidine-2,6-dione, HCl. Grades: > 99 %. CAS No. 24666-56-6. Molecular formula: C5H9ClN2O2. Mole weight: 164.59.
An impurity of Lenalidomide, a medication used for the treatment of myelodysplastic syndrome (MDS), multiple myeloma, and mantle cell lymphoma (MCL). Synonyms: 5-Amino-4-(4-amino-1-oxoisoindolin-2-yl)-5-oxopentanoic acid. CAS No. 2197414-57-4. Molecular formula: C13H15N3O4. Mole weight: 277.28.
Angiogenesis related Compound Library
A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); - Targets include angiogenesis signaling, and related targets such as S1P, VEGFR, PDGF, etc. ; - Includes approved drugs targeting angiogenesis, such as Sunitinib Malate, Lenalidomide, sorafenib, Erlotinib; drugs in clinical development with the most potential targeting angiogenesis, such as Vatalanib, Orantinib, 2-Methoxyestradiol (Panzem), Celecoxib; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4800. Categories: Angiogenesis related Compounds Libraries.
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