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Leukotriene D4 is a constituent of slow-reacting substance of anaphylaxis (SRS-A) and acts as an agonist of smooth muscle contraction. LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. Synonyms: Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl-; Glycine, N-[S-[1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl]-L-cysteinyl]-, [R-[R*,S*-(E,E,Z,Z)]]-; Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl-; S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinylglycine; Leukotriene D; LTD4. Grades: ≥97%. CAS No. 73836-78-9. Molecular formula: C25H40N2O6S. Mole weight: 496.66.
Leukotriene D4
Leukotriene D4 is a potent bronchoconstrictor. Leukotriene D4 has the potential for the research of asthma. Leukotriene D4 induces edema and increases capillary permeability [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 73836-78-9. Pack Sizes: 10 μg (201.34 μM * 100 μL in Ethanol); 50 μg (201.34 μM * 500 μL in Ethanol). Product ID: HY-113456.
Leukotriene D4 methyl ester
Leukotriene D4 methyl ester is a derivate of Leukotriene D4, which is a constituent of a slow-reacting substance of anaphylaxis (SRS-A) and acts as an agonist of smooth muscle contraction. LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. Synonyms: LTD4 methyl ester; Leukotriene D4 monomethyl ester; Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-1-hydroxy-5-methoxy-5-oxopentyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl-; Glycine, N-[S-[1-(1-hydroxy-5-methoxy-5-oxopentyl)-2,4,6,9-pentadecatetraenyl]-L-cysteinyl]-, [R-[R*,S*-(E,E,Z,Z)]]-; S-((5S,6R,7E,9E,11Z,14Z)-5-hydroxy-1-methoxy-1-oxoicosa-7,9,11,14-tetraen-6-yl)-L-cysteinylglycine. Grades: 95%. CAS No. 103476-23-9. Molecular formula: C26H42N2O6S. Mole weight: 510.69.
11-trans Leukotriene D4
11-trans Leukotriene D4 is a less potent C-11 double bond isomer of LTD4. Group: Biochemicals. Grades: Highly Purified. CAS No. 79768-40-4. Pack Sizes: 25ug, 50ug. Molecular Formula: C25H40N2O6S, Molecular Weight: 496.66. US Biological Life Sciences.
1, 1'-[Dithiobis (methylene) ]biscyclopropaneacetic Acid is an intermediate in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 162515-67-5. Pack Sizes: 50mg. US Biological Life Sciences.
1, 1'-[Dithiobis (methylene)]biscyclopropaneacetic Acid is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 1-[1-Carboxymethyl-cyclopropylmethyldisulfanylmethyl) cyclopropyl]acetic acid; Montelukast Disulfide Impurity; Cyclopropaneacetic acid, 1,1'-[dithiobis(methylene)]bis-; 2,2'-[Disulfanediylbis(methylene-1,1-cyclopropanediyl)]diacetic acid; 2, 2'- ( (Disulfanediylbis (methylene))bis (cyclopropane-1, 1-diyl))diacetic acid. Grades: ≥90%. CAS No. 162515-67-5. Molecular formula: C12H18O4S2. Mole weight: 290.40.
1, 1'-[Dithiobis (methylene) ]biscyclopropaneacetic Acid Methyl Ester is an intermediate in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 1446481-28-2. Pack Sizes: 100mg. US Biological Life Sciences.
1, 1'-[Dithiobis (methylene)]biscyclopropaneacetic Acid Methyl Ester is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: Montelukast Disulfide Dimethyl Ester; Methyl 2- (1- ( (2- ( (1-methoxycarbonylmethylcyclopropyl) methyl) disulfanyl) methyl)cyclopropyl)acetate; Cyclopropaneacetic acid, 1,1'-[dithiobis(methylene)]bis-, 1,1'-dimethyl ester; Dimethyl 2,2'-[disulfanediylbis(methylene-1,1-cyclopropanediyl)]diacetate. Grades: ≥90%. CAS No. 1446481-28-2. Molecular formula: C14H22O4S2. Mole weight: 318.45.
1- [ [ [ (1R) -1- [3- [ (2S, R) -2- [ [ (1-Carboxycyclopropyl) methyl] thio] -2- (7-chloro-2-quinolinyl) ethyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methylcyclopropaneacetic Acid is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C41H46ClNO5S2. Mole weight: 732.39.
1- ( (Benzyloxy) methyl ) cyclopropane carbaldehyde is an protected intermediate used in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
1- ( (Benzyloxy) methyl) cyclopropanecarbaldehyde
1- ( (Benzyloxy) methyl) cyclopropanecarbaldehyde is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: Cyclopropanecarboxaldehyde, 1-[(phenylmethoxy)methyl]-; 1-((Benzyloxy)methyl)cyclopropane-1-carbaldehyde. CAS No. 288401-39-8. Molecular formula: C12H14O2. Mole weight: 190.24.
[1- [ (Benzyloxy) methyl] cyclopropyl] methanol
[1- [ (Benzyloxy) methyl] cyclopropyl] methanol is an protected intermediate used in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Alternative Names: 1- [ (Phenylmethoxy) methyl] cyclopropanemethanol. Grades: Highly Purified. CAS No. 177200-76-9. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
[1-[ (Benzyloxy) methyl]cyclopropyl]methanol
[1-[ (Benzyloxy) methyl]cyclopropyl]methanol is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 1-[ (Phenylmethoxy) methyl]cyclopropanemethanol. Grades: ≥95%. CAS No. 177200-76-9. Molecular formula: C12H16O2. Mole weight: 192.25.
[1- [Bis (Benzyloxy) methyl] cyclopropyl] methanol is an protected intermediate used in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Alternative Names: ( ( (Cyclopropane-1, 1-diylbis (methylene))bis (oxy))bis (methylene))dibenzene. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
(1- (Cyanomethyl) cyclopropyl) methyl Methanesulfonate is an impurity of Montelukast (M568000), a selective leukotriene D4-receptor antagonist. Used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 152922-86-6. Pack Sizes: 100mg, 1g. Molecular Formula: C7H11NO3S, Molecular Weight: 189.23. US Biological Life Sciences.
(1-(Cyanomethyl)cyclopropyl)methyl Methanesulfonate is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 1-[[ (Methylsulfonyl) oxy]methyl]cyclopropaneacetonitrile. CAS No. 152922-86-6. Molecular formula: C7H11NO3S. Mole weight: 189.23.
1-Cyclopentylethanone-d4
1-Cyclopentylethanone-d4, is the labeled analogue of 1-Cyclopentylethanone (C988475), that can be used in the preparation of small molecule inhibitors of rifampicin resistant Staphylococcus aureus. An antibacterial agent. Also used in the synthesis of non-quinoline leukotriene D4 (LTD4) receptor antagonists. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C7H8D4O, Molecular Weight: 116.19. US Biological Life Sciences.
Worldwide
1- (Mercapto methyl ) cyclopropane acetonitrile
1- (Mercapto methyl ) cyclopropane acetonitrile is used as a reagent in the synthesis of Montelukast Sodium Salt (M568000); a selective leukotriene D4-receptor antagonist. Also used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 866923-64-0. Pack Sizes: 100mg, 1g. Molecular Formula: C6H9NS, Molecular Weight: 127.21. US Biological Life Sciences.
Worldwide
21(R)-Hydroxy Montelukast
21(R)-Hydroxy Montelukast is a metabolite of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: [R-[R*, R*- (E) ]]-1-[[[1-[3-[2- (7-Chloro-2-quinolinyl) ethenyl]phenyl]-3-hydroxy-3-[2- (1-hydroxy-1-methylethyl) phenyl]propyl]thio]methyl]-cyclopropaneacetic Acid; Montelukast M5b; {1-[ ({ (1R, 3R) -1-{3-[ (E) -2- (7-Chloro-2-quinolinyl) vinyl]phenyl}-3-hydroxy-3-[2- (2-hydroxy-2-propanyl) phenyl]propyl}sulfanyl) methyl]cyclopropyl}acetic acid; Cyclopropaneacetic acid, 1-[[[ (1R, 3R) -1-[3-[ (E) -2- (7-chloro-2-quinolinyl) ethenyl]phenyl]-3-hydroxy-3-[2- (1-hydroxy-1-methylethyl) phenyl]propyl]thio]methyl]-. Grades: 95%. CAS No. 184763-26-6. Molecular formula: C35H36ClNO4S. Mole weight: 602.18.
21(S)-Hydroxy Montelukast
21(S)-Hydroxy Montelukast is a metabolite of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: [R-[R*, S*- (E) ]]-1-[[[1-[3-[2- (7-Chloro-2-quinolinyl) ethenyl]phenyl]-3-hydroxy-3-[2- (1-hydroxy-1-methylethyl) phenyl]propyl]thio]methyl]-cyclopropaneacetic Acid; Montelukast M5a; {1-[ ({ (1R, 3S) -1-{3-[ (E) -2- (7-Chloro-2-quinolinyl) vinyl]phenyl}-3-hydroxy-3-[2- (2-hydroxy-2-propanyl) phenyl]propyl}sulfanyl) methyl]cyclopropyl}acetic acid; Cyclopropaneacetic acid, 1-[[[ (1R, 3S) -1-[3-[ (E) -2- (7-chloro-2-quinolinyl) ethenyl]phenyl]-3-hydroxy-3-[2- (1-hydroxy-1-methylethyl) phenyl]propyl]thio]methyl]-. Grades: 95%. CAS No. 184763-29-9. Molecular formula: C35H36ClNO4S. Mole weight: 602.18.
2-[2-[ (3S)-3-[3-[ (E)-2- (7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[ (methanesulfonyl)oxy]propyl]phenyl]-2-propanol is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: (αS)-α-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)benzenepropanol α-Methanesulfonate; Montelukast Impurity 35; Benzenepropanol, α-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)-, α-methanesulfonate, (αS)-; 2-[2-[ (3S)-3-[3-[ (E)-2- (7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[ (methanesulfonyl)oxy]propyl]phenyl]-2-propanol. Grades: ≥95%. CAS No. 807638-71-7. Molecular formula: C30H30ClNO4S. Mole weight: 536.08.
2,2-Dimethoxy-d6 Montelukast
2,2-Dimethoxy Montelukast is an intermediate in the synthesis of Methoxy-d3 Montelukast (M264527), a labeled impurity of Montelukast (M568000), a selective leukotriene D4-receptor antagonist. Used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C37H34D6ClNO3S, Molecular Weight: 620.27. US Biological Life Sciences.
2, 2'- ( (Disulfanediylbis (methylene))bis (cyclopropane-1, 1-diyl))bis (2-hydroxyacetic Acid) Diethyl Ester is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: Diethyl 2, 2'- ( (Disulfanediylbis (methylene))bis (cyclopropane-1, 1-diyl))bis (2-hydroxyacetate). Molecular formula: C16H26O6S2. Mole weight: 378.50.
2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol is a montelukast impurity, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: A montelukast impurity. Synonyms: (S)-α-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)benzenepropanol. CAS No. 287930-77-2. Molecular formula: C29H28ClNO2. Mole weight: 457.99.
2-[(3S)-3-(Acetyloxy)-1-bromo-3-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]-benzoic Acid Methyl Ester is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: An intermediate in the synthesis of montelukast. Synonyms: methyl 2-((3S)-3-acetoxy-1-bromo-3-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)benzoate; [3S(E)]-2-[3-(Acetyloxy)-1-bromo-3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]-benzoic Acid Methyl Ester; Benzoic acid, 2-[(3S)-3-(acetyloxy)-1-bromo-3-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]-, methyl ester. CAS No. 184763-69-7. Molecular formula: C30H25BrClNO4. Mole weight: 578.88.
25-Hydroxy Montelukast
25-Hydroxy Montelukast is a metabolite of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: A metabolite of montelukast. Synonyms: 1- [ [ [ (1R) -1- [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [4-hydroxy-2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic Acid; Montelukast M3; Cyclopropaneacetic acid, 1-[[[ (1R) -1-[3-[ (1E) -2- (7-chloro-2-quinolinyl) ethenyl]phenyl]-3-[4-hydroxy-2- (1-hydroxy-1-methylethyl) phenyl]propyl]thio]methyl]-; {1-[ ({ (1R) -1-{3-[ (E) -2- (7-Chloro-2-quinolinyl) vinyl]phenyl}-3-[4-hydroxy-2- (2-hydroxy-2-propanyl) phenyl]propyl}sulfanyl) methyl]cyclopropyl}acetic acid. Grades: ≥95%. CAS No. 200804-28-0. Molecular formula: C35H36ClNO4S. Mole weight: 602.18.
2-Des(1-hydroxy-1-methylethyl)-2-carboxy Montelukast Bissodium Salt
2-Des(1-hydroxy-1-methylethyl)-2-carboxy Montelukast Bissodium Salt is an impurity of Montelukast Sodium Salt (M568000), a selective leukotriene D4-receptor antagonist. Used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 500mg. Molecular Formula: C33H28ClNNa2O4S, Molecular Weight: 616.08. US Biological Life Sciences.
2-Des(1-hydroxy-1-methylethyl)-2-methycarboxy Montelukast Hydrochloride is an impurity of Montelukast (M568000), a selective leukotriene D4-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 906107-37-7. Pack Sizes: 25mg, 100mg. Molecular Formula: C34H33Cl2NO4S. US Biological Life Sciences.
2-((E)-3-((1S)-1-((tert-Butyldimethylsilyl)oxy)-3-(2-(2-((tert-butyldimethylsilyl)oxy)oxiran-2-yl)phenyl)propyl)styryl)-7-chloroquinoline 1-Oxide is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Grades: 98%. Molecular formula: C40H52ClNO4Si2. Mole weight: 702.47.
2-Hydroxy-2- (1- (hydroxymethyl) cyclopropyl) acetamide Benzyl Ester is an protected intermediate used in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
2-Hydroxy-2- (1- (hydroxymethyl) cyclopropyl) acetic Acid Benzyl Ester is an intermediate in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
2-Hydroxy-2- (1- (hydroxymethyl) cyclopropyl) acetonitrile Benzyl Ester is an protected intermediate used in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
2-Hydroxy-2- (1- (mercaptomethyl) cyclopropyl) acetic Acid is an substituent used in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C6H10O3S. US Biological Life Sciences.
2-Hydroxy-2-(1-(mercaptomethyl)cyclopropyl)acetic Acid is a substituent in the synthesis of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Grades: 98%. Molecular formula: C6H10O3S. Mole weight: 162.21.
2-Methoxymethyl Montelukast 1,2-Diol (Mixture of Diastereomers)
2-Methoxymethyl Montelukast 1,2-Diol (Mixture of Diastereomers) is an intermediate in the production of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: Intermediate in the production of montelukast metabolites. Synonyms: [1- ({ [ (1R) -1-{3- [ (E) -2- (7-Chloro-2-quinolinyl) vinyl] phenyl}-3-{2- [2-hydroxy-1- (methoxymethoxy) -2-propanyl] phenyl}propyl] sulfanyl}methyl) cyclopropyl] acetic acid; Cyclopropaneacetic acid, 1- [ [ [ (1R) -1- [3- [ (E) -2- (7-chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- [1-hydroxy-2- (methoxymethoxy) -1-methylethyl] phenyl] propyl] thio] methyl] -; 1- [ [ [ (1R) -1- [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- [1-hydroxy-2- (methoxymethoxy) -1-methylethyl] phenyl] propyl] thio] methyl] cyclopropaneacetic Acid. Grades: ≥95%. CAS No. 184764-27-0. Molecular formula: C37H40ClNO5S. Mole weight: 646.24.
(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-4,5-dihydro-2-benzoxepin-1(3H)-one is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: An impurity formed during the preparation of montelukast. Synonyms: (3S)-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-4,5-dihydro-3H-2-benzoxepin-1-one; (3S)-3-[3-[(1E)-2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-4,5-DIHYDRO-2-BENZOXEPIN-1(3H)-ONE; SCHEMBL2564296; ZINC38601565; HE168455. Grades: 95%. CAS No. 1100617-38-6. Molecular formula: C27H20ClNO2. Mole weight: 425.91.
5- (1- (Hydroxymethyl) cyclopropyl) -2, 2-dimethyl-1, 3-dioxolan-4-one is an intermediate in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
5-(1-(Hydroxymethyl)cyclopropyl)-2,2-dimethyl-1,3-dioxolan-4-one is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C9H14O4. Mole weight: 186.20.
5- (1- (Hydroxymethyl) cyclopropyl) -2, 2-dimethyl-1, 3-dioxolan-4-one Benzyl Ester is an intermediate in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
5-(1-(Hydroxymethyl)cyclopropyl)-2,2-dimethyl-1,3-dioxolan-4-one Benzyl Ester is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C16H20O4. Mole weight: 276.33.
5s-12r-Dihydroxy-6z,8e,10e,14z-eicosatetraenoic-6,7,14,15-d4 acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5S-12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENOIC-6,7,14,15-D4 ACID;LEUKOTRIENE B4-D4. Product Category: Heterocyclic Organic Compound. Appearance: A solution in acetonitrile. CAS No. 124629-74-9. Molecular formula: C20H28D4O4. Mole weight: 340.49. Product ID: ACM124629749. Alfa Chemistry ISO 9001:2015 Certified.
Cilastatin Ammonium Salt
Cilastatin Ammonium Salt is the ammonium salt of Cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Synonyms: (2Z)-7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid Ammonium Salt; MK-791 Ammonium Salt. Grades: > 95%. CAS No. 877674-82-3. Molecular formula: C16H29N3O5S. Mole weight: 375.48.
Cilastatin sodium
Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Synonyms: L 642957; MK 791; L642957; MK791; L-642957; MK-791; [R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt; (2Z) ?-7- [ [ (2R) ?-2-Amino-2-carboxyethyl] ?thio] ?-2- [ [ [ (1S) ?-2, ?2-dimethylcyclopropyl] ?carbonyl] ?amino] ?-2-heptenoic Acid Sodium Salt; sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate. Grades: ≥99% by HPLC. CAS No. 81129-83-1. Molecular formula: C16H25N2NaO5S. Mole weight: 380.43.
Cinalukast
Cinalukast is a selective Leukotriene D4 receptor antagonist originated by Roche and IC 50 value is 6.4 nM. Cinalukast inhibits the actions of Leukotriene D4 at the CysLT1 receptor and it can prevent airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. Treatment for Asthma was discontinued. Uses: Asthma. Synonyms: Ro 24-5913; UNII-5E1O433QAI; CHEMBL283754;4-[[3-[(1E)-2-(4-Cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxo-Butanoic Acid. Grades: 98 %. CAS No. 128312-51-6. Molecular formula: C23H28N2O3S. Mole weight: 412.55.
CP-199330
CP-199330, a chromen derivative, has been found to be a Leukotriene D4 receptor antagonist that was once studied against asthma by Pfizer. Synonyms: CP-199330; CP 199330; CP199330; UNII-V4WYK6T8QA; CHEMBL96206; V4WYK6T8QA; SCHEMBL8890632; BDBM50081532; N-[3-[[(3R,4R)-6-[(7-chloroquinolin-2-yl)methoxy]-4-hydroxy-3,4-dihydro-2H-chromen-3-yl]methyl]-4-methoxyphenyl]-1,1,1-trifluoromethanesulfonamide. Grades: 98%. CAS No. 158102-92-2. Molecular formula: C28H24ClF3N2O6S. Mole weight: 609.01.
CP-199330 Sodium
The sodium salt form of CP-199330 which is a chromen derivative and has been found to be a Leukotriene D4 receptor antagonist that was once studied against asthma by Pfizer. Synonyms: CP-199330 sodium; CP 199330 sodium; CP199330 sodium; CP-199330 monosodium salt; Methanesulfonamide, N-(3-((6-((7-chloro-2-quinolinyl)methoxy)-3,4-dihydro-4-hydroxy-2H-1-benzopyran-3-yl)methyl)-4-methoxyphenyl)-1,1,1-trifluoro-, monosodium salt, (3R-cis)-; UNII-74573Q728X component FZCWCSNK. Grades: 98%. CAS No. 158102-98-8. Molecular formula: C28H23ClF3N2NaO6S. Mole weight: 630.99.
Des[3-[[ (1-Carboxymethyl) cyclopropyl]methyl]thio]-2-propenyl Montelukast Mesylate is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 2-[(2E)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-2-propen-1-yl]-α,α-dimethyl-benzenemethanol Methanesulfonate. CAS No. 1187586-82-8. Molecular formula: C30H30ClNO4S. Mole weight: 536.08.
FPL 55712
FPL 55712 is a leukotriene receptor antagonist that inhibits contraction of guinea pig trachealis induced by leukotrienes C4, D4, E4 and F4. Synonyms: FPL 55712; FPL55712; FPL-55712; 7-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid. Grades: ≥97% by HPLC. CAS No. 40785-97-5. Molecular formula: C27H30O9. Mole weight: 498.52.
Ibudilast-d3 (Major)
Labeled Ibudilast. A leukotriene D4 antagonist. Used as an antiallergic, antiasthmatic, and vasodilator (cerebral). Group: Biochemicals. Alternative Names: 2-Methyl-1-[2- (1-methylethyl) pyrazolo[1, 5-a]pyridin-3-yl]-1-propanone-d3; 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one-d3; 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine-d3; 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine-d3; AV 411-d3; KC 404-d3; Ketas-d3. Grades: Highly Purified. CAS No. 102064-45-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
iralukast
Iralukast is a Leukotriene D4 receptor antagonist originated by Novartis as a a structural analogue of LTD4. It is applicated for the treatment of asthma and inflammatory effects of these leukotrienesand. Uses: Asthma. Synonyms: Cgp 45715A; Cgp-45715A; Cgp45715A;sodium;6-acetyl-3-[(5E,7E,10R)-9-(2-carboxy-4-oxochromen-7-yl)sulfanyl-10-hydroxy-10-[3-(trifluoromethyl)phenyl]deca-5,7-dienoxy]-2-propylphenolate. Grades: 98%. CAS No. 125617-94-9. Molecular formula: C38H36F3NaO8S. Mole weight: 732.74.
LY171883
LY171883 is an orally available leukotriene D4 receptor antagonist. Uses: Leukotriene antagonists. Synonyms: LY-171883; LY 171883; Tomelukast; 1-[2-hydroxy-3-propyl-4-[4-(2H-tetrazol-5-yl)butoxy]phenyl]ethanone. Grades: ≥98%. CAS No. 88107-10-2. Molecular formula: C16H22N4O3. Mole weight: 318.4.
LY 203647
LY 203647 is a a leukotriene D4 and E4 receptor antagonist with a tetrazole nucleus structure originated by Eli Lilly. No development for treatment of Ischaemic heart disorders by LY 203647 has been reported yet. Uses: Ischaemic heart disorders. Synonyms: LY 203647; LY203647; LY-203647; 1-(2-hydroxy-3-propyl-4-(4-(2-(4-(1H-tetrazol-5-yl)butyl)-2H-tetrazol-5-yl)butoxy)phenyl)-Ethanone. Grades: 98%. CAS No. 122009-61-4. Molecular formula: C21H30N8O3. Mole weight: 442.52.
LY 290324
LY 290324, a quinoline derivative, has been found to be a Leukotriene D4 receptor antagonist that could be probably effective as antiallergic and antiasthmatic agent. It has no development-reported since 1998. Synonyms: LY290324; LY-290324; 5-(2-(1-(3-(2-(7-Chloroquinolin-2-yl)ethenyl)benzyl)indol-7-yl)ethyl)-1H-tetrazole. Grades: 98%. CAS No. 146554-87-2. Molecular formula: C29H24Cl2N6. Mole weight: 527.45.
Methoxy Montelukast Methyl Ester
Methoxy Montelukast Methyl Ester is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: methyl 2- [1- [ [ (1R) -1- [3- [ (E) -2- (7-chloroquinolin-2-yl) ethenyl] phenyl] -3- [2- (2-methoxypropan-2-yl) phenyl] propyl] sulfanylmethyl] cyclopropyl] acetate. Molecular formula: C37H40ClNO3S. Mole weight: 614.23.
(S,E)-2-(3-((tert-Butyldimethylsilyl)oxy)-3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)benzoic Acid Methyl Ester is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: methyl 2-[(3S)-3-[tert-butyl(dimethyl)silyl]oxy-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]propyl]benzoate; (S,E)-2-(3-((tert-Butyldimethylsilyl)oxy)-3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)benzoic; (S,E)-2-(3-((tert-Butyldimethylsilyl)oxy)-3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)benzoic Acid Methyl Ester. CAS No. 1772578-77-4. Molecular formula: C34H38ClNO3Si. Mole weight: 572.21.
Montelukast Acyl-β-D-glucuronide Acetic Acid Salt
Montelukast Acyl-β-D-glucuronide Acetic Acid Salt is a metabolite of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 1-O- ({1-[ ({ (1R) -1-{3-[ (E) -2- (7-Chloro-2-quinolinyl) vinyl]phenyl}-3-[2- (2-hydroxy-2-propanyl) phenyl]propyl}sulfanyl) methyl]cyclopropyl}acetyl) -α -D-erythro-hexopyranuronic acid acetate (1:1); α-D-erythro-Hexopyranuronic acid, 1- [2- [1- [ [ [ (1R) -1- [3- [ (E) -2- (7-chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropyl] acetate] , acetate (1:1) (salt); 1- [1- [ [ [ (1R) -1- [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetate] β-D-Glucopyranuronic Acid Acetic Acid Salt; Montelukast M1 Acetic acid Salt. Grades: ≥95%. Molecular formula: C43H48ClNO11S. Mole weight: 822.36.
Montelukast Bis-sulfide (mixture of diastereomers)
Montelukast Bis-sulfide (mixture of diastereomers) is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 1- [ [ [ (1R) -1- [3- [ (1R, S) -1- [ [ [1- (Carboxymethyl) cyclopropyl] methyl] thio] -2- (7-chloro-2-quinolinyl) ethyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic Acid; Montelukast Michael Aduct. CAS No. 1242260-05-4. Molecular formula: C41H46ClNO5S2. Mole weight: 732.39.
A selective leukotriene D4-receptor antagonist. Used as an antiasthmatic. Group: Biochemicals. Alternative Names: 1- [1- [ [ [ (1R) -1- [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl-d6) phenyl] propyl] thio] methyl] cyclopropaneacetic Acid Sodium Salt; MK-476-d6, Singulair. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Montelukast Dicarboxylic Acid (Mixture of Diastereomers)
Montelukast Dicarboxylic Acid (Mixture of Diastereomers) is a metabolite of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 2-[ (3R) -3-[[[1- (Carboxymethyl) cyclopropyl]methyl]thio]-3-[3-[ (1E) -2- (7-chloro-2-quinolinyl) ethenyl]phenyl]propyl]-α -hydroxy-α -methylbenzeneacetic Acid; Benzeneacetic acid, 2-[ (3R) -3-[[[1- (carboxymethyl) cyclopropyl]methyl]thio]-3-[3-[ (E) -2- (7-chloro-2-quinolinyl) ethenyl]phenyl]propyl]-α -hydroxy-α -methyl-. Grades: ≥90%. CAS No. 213380-27-9. Molecular formula: C35H34ClNO5S. Mole weight: 616.17.
Montelukast Dicyclohexylamine Salt
A selective leukotriene D4-receptor antagonist. Used as an antiasthmatic. Group: Biochemicals. Alternative Names: 1- [1- [ [ [ (1R) -1- [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic N-Cyclohexyl cyclohexanamine; Montelukast DCHA. Grades: Highly Purified. CAS No. 577953-88-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Montelukast Dicyclohexylamine Salt
Montelukast is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: A selective leukotriene d4-receptor antagonist. used as an antiasthmatic. Synonyms: 1- [1- [ [ [ (1R) -1- [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic N-Cyclohexylcyclohexanamine; Montelukast DCHA. Grades: 95%. CAS No. 577953-88-9. Molecular formula: C47H59ClN2O3S. Mole weight: 767.50.
Montelukast Gem-dimethylmethylene Analogue
Montelukast Gem-dimethylmethylene Analogue is an analog of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Uses: An analog of montelukast, used for preparation of mk-0476. Synonyms: [R- (E) ]-3-[[[1-[3-[2- (7-Chloro-2-quinolinyl) ethenyl]phenyl]-3-[2- (1-hydroxy-1-methylethyl) phenyl]propyl]thio]methyl]-3-methylbutanoic Acid; 4-({(1R)-1-{3-[(E)-2-(7-Chloro-2-quinolinyl)vinyl]phenyl}-3-[2-(2-hydroxy-2-propanyl)phenyl]propyl}sulfanyl)-3,3-dimethylbutanoic acid; Butanoic acid, 4-[[(1R)-1-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]-3,3-dimethyl-; 4-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanyl}-3,3-dimethyl-butyric acid. Grades: ≥95%. CAS No. 162489-70-5. Molecular formula: C35H38ClNO3S. Mole weight: 588.20.
Montelukast Impurity 11
Montelukast Impurity 11 is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C20H16ClNO. Mole weight: 321.80.
Montelukast Impurity 12
Montelukast Impurity 12 is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Grades: 98%. Molecular formula: C35H32ClNNa2O5S. Mole weight: 660.13.
Montelukast Impurity 14
Montelukast Impurity 14 is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C35H36ClNO4S. Mole weight: 602.18.
Montelukast Impurity 15
Montelukast Impurity 15 is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C35H37NO3S. Mole weight: 551.74.
Montelukast Impurity 16
Montelukast Impurity 16 is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: (R, E) -2- (2- (3- (3- (2- (7-chloroquinolin-2-yl) vinyl) phenyl) -3- ( (2-methylenebutyl) thio) propyl) phenyl) propan-2-ol. Molecular formula: C34H36ClNOS. Mole weight: 542.17.
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