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| Product | Description | |
|---|---|---|
| Lipoic acid | Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-(+)-α-Lipoic acid; R-(+)-Thioctic acid. CAS No. 1200-22-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-18733. |  |
| Lipoic acid, reduced | Lipoic acid, reduced. Group: Biochemicals. Alternative Names: (±)-6,8-Dimercaptooctanoic acid; (±)-Dihydrolipoic acid. Grades: Highly Purified. CAS No. 462-20-4. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C8H16O2S2. US Biological Life Sciences. |  Worldwide |
| Lipoic Acid (Thioctic Acid, Alpha Lipoic Acid) | Coenzyme in the oxidative decarboxylation reactions of glucose metabolism and the citric acid cycle. Although it is an essential growth factor for various micro-organisms. a-Lipoic acid, is a naturally occuring coenzyme containing a disulfide that has been used to treat polyneuropathies and hepatic disorders. a-Lipoic acid is a potent inhibitor of NFKB activation and HIV-1 tat driven gene expression. Group: Biochemicals. Alternative Names: (+/-)-1,2-Dithiolane-3-pentanoic Acid; (+/-)-1,2-Dithiolane-3-valeric Acid; (+/-)-Thioctic Acid; (RS)-α-Lipoic Acid; DL-Thioctic Acid; Liposan; Lipothion; NSC 628502; NSC 90788; Protogen A; Thioctsan; Tioctacid. Grades: Cell Culture Grade. CAS No. 1077-28-7. Pack Sizes: 10g, 25g, 100g, 500g. Molecular Formula: C8H14O2S2, Molecular Weight: 206.3. US Biological Life Sciences. | Worldwide |
| (±)-α-Lipoic Acid Methyl Ester-d5 | (±)-α-Lipoic Acid Methyl Ester-d5 is an intermediate used in the synthesis of rac α-Lipoic Acid-d5 (L468752), which is a fat-metabolism stimulator. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C9H11D5O2S2, Molecular Weight: 225.38. US Biological Life Sciences. | Worldwide |
| a-Lipoic acid | a-Lipoic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 62-46-4. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C8H14O2S2. US Biological Life Sciences. | Worldwide |
| (+)-a-Lipoic Acid ((R)-(+)-1,2-Dithiolane-3-pentanoic Acid,) | (+)-a-Lipoic Acid ((R)-(+)-1,2-Dithiolane-3-pentanoic Acid,). Group: Biochemicals. Alternative Names: (R)-(+)-1,2-Dithiolane-3-pentanoic Acid. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| a-Lipoic Acid (Thioctic Acid) | a-Lipoic Acid (Thioctic Acid). Group: Biochemicals. Alternative Names: Thioctic Acid. Grades: Highly Purified. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| α-Lipoic acid | α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DL-6-Thioctic acid. Product Category: Inhibitors. Appearance: Yellow powder. CAS No. 1077-28-7. Molecular formula: C8H14O2S2. Mole weight: 206.33. Purity: 0.98. IUPACName: 5-(Dithiolan-3-yl)pentanoic acid. Canonical SMILES: C1CSSC1CCCCC(=O)O. Density: 1.2888 g/cm³. Product ID: ACM1077287-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| α-Lipoic Acid | α-Lipoic Acid is a metabolic antioxidant that regulates NFκB signal transduction and can protect against oxidative injury. The exogenous compound is reduced intracellularly by enzymes. Its reduced form is involved in radical scavenging, recycling of other antioxidants, accelerating GSH synthesis, and regulating transcription factor activity, specifically NFkappaB. It also acts as a conenzyme that is required for the activity of pyruvate dehydrogenase and glycine decarboxylase, among other enzyme complexes. Studies show that it can prevent a decrease in the renal antioxidant defense system and prevent the increase of lipid peroxidation, platinum content and plasma creatinine concentrations. In other studies, lipoic acid decreased the phagocytosis of myelin by macrophages, acting as a non-specific scavenger of reactive oxygen species (ROS). Applications: A metabolic antioxidant that regulates nf-κb signal transduction. Group: Coenzymes. Synonyms: DL-Thioctic Acid; DL-6,8-Dithiooctanoic acid; 1,2-Dithiolane-3-valeric acid. CAS No. 1077-28-7. Purity: ≥95%. Mole weight: 206.32. Form: Solid. DL-Thioctic Acid; DL-6,8-Dithiooctanoic acid; 1,2-Dithiolane-3-valeric acid; α-Lipoic Acid; 1077-28-7. Cat No: COEC-041. |  |
| α-Lipoic Acid | α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB -dependent HIV-1 LTR activation [1] [2] [3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells [4]. α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Thioctic acid; (±)-α-Lipoic acid; DL-α-Lipoic acid. CAS No. 1077-28-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N0492. | |
| Alpha Lipoic Acid | Alpha Lipoic Acid or ALA, is found in healthy foods such as spinach, chard, collard greens and broccoli, foods often deficient in standard American diets. It is an antioxidant that is found in every human cell. ALA at 5 % has been shown to reduce fine lines caused by sun damage. Uses: Anti-oxidants. Group: Skin Care Active Ingredients. INCI Name: Thioctic Acid. CAS Number: 1077-28-7. |  United States and all of its trading partners.. |
| Alpha Lipoic Acid | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. |  |
| α-Lipoic acid-NHS | ?-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DL-?-Lipoic acid-NHS. CAS No. 40846-94-4. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-141336. | |
| α-Lipoic Acid sodium | α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB -dependent HIV-1 LTR activation [1] [2] [3]. α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells [4]. α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Thioctic acid sodium; (±)-α-Lipoic acid sodium; DL-α-Lipoic acid sodium. CAS No. 2319-84-8. Pack Sizes: 100 mg; 250 mg. Product ID: HY-N0492A. | |
| α-Lipoic Acid (Standard) | α-Lipoic Acid (Standard) is the analytical standard of α-Lipoic Acid. This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB -dependent HIV-1 LTR activation [1] [2] [3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells [4]. α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Thioctic acid (Standard); (±)-α-Lipoic acid (Standard); DL-α-Lipoic acid (Standard). CAS No. 1077-28-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0492R. | |
| Alpha-lipoic Acid USP | Alpha-lipoic Acid USP. CAS No. 1077-28-7. Molecular formula: C8H14O2S2. |  |
| Alpha Lipoic Acid USP | Alpha Lipoic Acid USP. |  CA, FL & NJ |
| DL-a-Lipoic acid NHS 99+% (NMR) | DL-a-Lipoic acid NHS 99+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| DL-alpha-Lipoic acid (DL Thioctic acid) | 25g Pack Size. Group: Bioactive Small Molecules, Building Blocks, Chiral Compounds, Flavours and Fragrance Materials. Formula: C8H14O2S2. CAS No. 1077-28-7. Prepack ID 27534819-25g. Molecular Weight 206.33. See USA prepack pricing. |  |
| DL-alpha-Lipoic acid (DL Thioctic acid) | 5g Pack Size. Group: Bioactive Small Molecules, Building Blocks, Chiral Compounds, Flavours and Fragrance Materials. Formula: C8H14O2S2. CAS No. 1077-28-7. Prepack ID 27534819-5g. Molecular Weight 206.33. See USA prepack pricing. | |
| DL-alpha-Lipoic acid NHS | DL-alpha-Lipoic acid NHS. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| γ-Lipoic Acid | γ-Lipoic Acid. Group: Biochemicals. Alternative Names: 6,8-Dimercaptooctanoic Acid; (±)-Dihydro-α-lipoic Acid; (±)-Dihydrolipoic Acid; DL-Dihydro-α-lipoic Acid; Dihydrolipoic Acid; Dihydrothioctic Acid; Reduced Lipoic Acid; Reduced Thioctic Acid; Dihydrothioctic Acid; dl-Dihydrolipoic Acid. Grades: Highly Purified. CAS No. 462-20-4. Pack Sizes: 500mg. Molecular Formula: C8H16O2S2, Molecular Weight: 208.34. US Biological Life Sciences. | Worldwide |
| Homo-a-lipoic acid | Homo-a-lipoic acid. Group: Biochemicals. Alternative Names: 1,2-Dithiolane-3-hexanoic acid; 1,2-Dithiolane-3-caproic acid. Grades: Highly Purified. CAS No. 5616-71-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C9H16O2S2. US Biological Life Sciences. | Worldwide |
| ?-Lipoic acid | ?-Lipoic acid. CAS No: 1077-28-7 |  Sarchem Laboratories New Jersey NJ |
| (±)-?-Lipoic acid | synthetic, ?99% (titration), powder. Group: Fluorescence/luminescence spectroscopy. | |
| rac a-lipoic acid | rac a-lipoic acid. Group: Biochemicals. Alternative Names: (+/-)-1,2-Dithiolane-3-pentanoic acid; (+/-)-1,2-Dithiolane-3-valeric acid; (+/-)-Thioctic acid. Grades: Highly Purified. CAS No. 1077-28-7. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C8H14O2S2. US Biological Life Sciences. | Worldwide |
| rac α-Lipoic Acid-d5 | A fat-metabolism stimulator. Group: Biochemicals. Alternative Names: (+/-)-1,2-Dithiolane-3-pentanoic Acid-d5; (+/-)-1,2-Dithiolane-3-valeric Acid-d5; (+/-)-Thioctic Acid-d5; (RS)-α-Lipoic Acid-d5;DL-Thioctic Acid-d5; Liposan-d5; Lipothion-d5; NSC 628502-d5; NSC 90788-d5; Protogen A-d5; Thioctsan-d5; Tioctacid-d5. Grades: Highly Purified. CAS No. 1189471-66-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| rac α-Lipoic Acid-d5 | rac α-Lipoic Acid-d5. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (+/-)-1,2-Dithiolane-3-pentanoic Acid-d5; (+/-)-1,2-Dithiolane-3-valeric Acid-d5; (+/-)-Thioctic Acid-d5; (RS)-α-Lipoic Acid-d5;DL-Thioctic Acid-d5; Liposan-d5; Lipothion-d5; NSC 628502-d5; NSC 90788-d5; Protogen A-d5; Thioctsan-d5; Tioctacid-d5. Product Category: Heterocyclic Organic Compound. Appearance: Pale Yellow Solid. CAS No. 1189471-66-6. Molecular formula: C8H9D5O2S2. Mole weight: 211.36. Purity: 0.96. IUPACName: 5,5-dideuterio-5-(3,4,4-trideuteriodithiolan-3-yl)pentanoic acid. Canonical SMILES: C1CSSC1CCCCC(=O)O. Product ID: ACM1189471666. Alfa Chemistry ISO 9001:2015 Certified. | |
| rac α-Lipoic Acid-[d5] | rac α-Lipoic Acid-[d5] is the labelled analogue of rac α-Lipoic Acid, which is a fat-metabolism stimulator. Synonyms: Alpha Lipoic acid-d5; rac α-Lipoic Acid-d5; (+/-)-1,2-Dithiolane-3-pentanoic Acid-d5; (+/-)-1,2-Dithiolane-3-valeric Acid-d5; (+/-)-Thioctic Acid-d5; (RS)-α-Lipoic Acid-d5; DL-Thioctic Acid-d5; Liposan-d5; Lipothion-d5; NSC 628502-d5; NSC 90788-d5; Protogen A-d5; Thioctsan-d5; Tioctacid-d5. Grade: ≥96% by HPLC; 99% atom D. CAS No. 1189471-66-6. Molecular formula: C8H9D5O2S2. Mole weight: 211.35. |  |
| (R)-(+)-a-Lipoic acid | (R)-(+)-a-Lipoic acid. Group: Biochemicals. Alternative Names: (3R)-1,2-Dithiolane-3-pentanoic acid; (R)-(+)-1,2-Dithiolane-3-pentanoic acid; (+)-1,2-Dithiolane-3-valeric acid. Grades: Highly Purified. CAS No. 1200-22-2. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C8H14O2S2. US Biological Life Sciences. | Worldwide |
| (R)-alpha-Lipoic Acid | (R)-alpha-Lipoic Acid, a vitamin-like organosulfur compound, is widely used as a dietary supplement and antioxidant. It has been also found to influence the activity of nuclear factor kappa-B (NF-κB). Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: (R)-lipoic acid; (+)-alpha-Lipoic acid; (R)-5-(1,2-Dithiolan-3-yl)pentanoic acid; R-(+)-alpha-Lipoic acid; 5-[(3R)-dithiolan-3-yl]pentanoic acid. Grade: 98%. CAS No. 1200-22-2. Molecular formula: C8H14O2S2. Mole weight: 206.318. | |
| R-Alpha Lipoic Acid Sodium Salt | R-Alpha Lipoic Acid Sodium Salt. CAS No. 176110-81-9. | CA, FL & NJ |
| (R)-(+)-?-Lipoic acid | analytical standard. Group: Application areas. | |
| (S)-(-)-a-Lipoic acid | (S)-(-)-a-Lipoic acid. Group: Biochemicals. Alternative Names: (3S)-1,2-Dithiolane-3-pentanoic acid; (S)-(-)-Thioctic acid. Grades: Highly Purified. CAS No. 1077-27-6. Pack Sizes: 500mg, 1g. Molecular Formula: C8H14O2S2. US Biological Life Sciences. | Worldwide |
| 6,8-Dichlorooctanoic Acid Ethyl Ester | 6,8-Dichlorooctanoic Acid Ethyl Ester is an industrial toxin as well as an intermediate product of lipoic acid synthesis. Group: Biochemicals. Alternative Names: Ethyl 6,8-Dichlorooctanoate. Grades: Highly Purified. CAS No. 1070-64-0. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| 6-Hydroxy-8-[(phenylmethyl)thio]-octanoic Acid Methyl Ester-d5 | Used in the preparation of Lipoic Acid and its derivatives. Group: Biochemicals. Alternative Names: 8-(Benzylthio)-6-hydroxy-octanoic Acid Methyl Ester-d5. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 8-(Benzylthio)-6-oxo-octanoic Acid Methyl Ester-d4 | Used in the preparation of Lipoic Acid and its derivatives. Group: Biochemicals. Alternative Names: 6-Oxo-8-[(phenylmethyl)thio]-octanoic Acid Methyl Ester-d4. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 8-Chloro-6-oxo-octanoic Acid Ethyl Ester | Intermediate in the synthesis of Lipoic Acid and its derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 50628-91-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 8-Methoxy-6-oxo-octanoic Acid Methyl Ester-d4 | Used in the synthesis of Lipoic Acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (+/-)-alpha-Lipoamide | (+/-)-alpha-Lipoamide is a coenzyme, which transfer acetyl and hydrogen in Pyruvate deacylation oxidation process. It may be used in treatment of insulin resistance by stimulating mitochondrial biogenesis. It has shown to have a good therapeutic effect on early diabetic nephropathy when used in combination with Alprostadil. Uses: (+/-)-alpha-lipoamide may be used in treatment of insulin resistance by stimulating mitochondrial biogenesis. it has shown to have a good therapeutic effect on early diabetic nephropathy. Synonyms: Lipoamide; Lipoacin; NSC 90787; NSC-90787; NSC90787; Lipoamide; Thioctamide; Thioctic acid amide; Vitamin N; Alpha-Lipoic acid amide; 5-(Dithiolan-3-yl)pentanamide; (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide; 1,2-Dithiolane-3-pentanamide. Grade: >98 %. CAS No. 940-69-2. Molecular formula: C8H15NOS2. Mole weight: 205.34. | |
| CAY10506 | Peroxisome proliferator-activated receptor gamma (PPARγ), also known as the glitazone receptor, or NR1C3, is a type II nuclear receptor that in humans is encoded by the PPARG gene. CAY10506 is a PPARγ agonist, which is a nuclear transcription factor that controls lipid homeostasis and glucose metabolism. It is a hybrid lipoic acid (anti-diabetic drugs of the thiazolidinedione) TZD derivative that transactivates human PPARγ with an EC50 value of 10 μM. Synonyms: CAY 10506; CAY-10506. Grade: ≥98%. CAS No. 292615-75-9. Molecular formula: C20H26N2O4S3. Mole weight: 454.6. | |
| CPI-613 | CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities. Although the exact mechanism of action is unknown, alpha-lipoic acid analogue CPI-613 has been shown to inhibit metabolic and regulatory processes required for cell growth in solid tumors. Both enantiomers in the racemic mixture exhibit antineoplastic activity. The mechanism-of-action of CPI-613 appears distinct from the current classes of anti-cancer agents used in the clinic. CPI-613 demonstrates both in vitro and in vivo anti-tumor activity. CPI-613 was known to strongly disrupt tumor mitochondrial metabolism. CPI-613 disruption of tumor mitochondrial metabolism is followed by efficient commitment to cell death by multiple, apparently redundant pathways, including apoptosis, in all tested cancer cell lines. Further, CPI-613 shows strong antitumor activity in vivo against human non-small cell lung and pancreatic cancers in xenograft models with low side-effect toxicity. Synonyms: CPI613; CPI 613; Devimistat; 6,8-bis(benzylthio)octanoic acid. Grade: 98%. CAS No. 95809-78-2. Molecular formula: C22H28O2S2. Mole weight: 388.59. | |
| Devimistat | Devimistat (CPI-613) is a mitochondrial metabolism inhibitor. Devimistat is a lipoic acid antagonist that abrogates mitochondrial energy metabolism to induce apoptosis in various cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPI-613. CAS No. 95809-78-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15453. | |
| Diaphorase 22 from Recombinant E.coli | A flavoprotein (FAD). A component of the multienzyme 2-oxo-acid dehydrogenase complexes. In the pyruvate dehydrogenase complex, it binds to the core of EC 2.3.1.12, dihydrolipoyllysine-residue acetyltransferase, and catalyses oxidation of its dihydrolipoyl groups. It plays a similar role in the oxoglutarate and 3-methyl-2-oxobutanoate dehydrogenase complexes. Another substrate is the dihydrolipoyl group in the H-protein of the glycine-cleavage system (click here for diagram), in which it acts, together with EC 1.4.4.2, glycine dehydrogenase (decarboxylating), and EC 2.1.2.10, aminomethyltransferase, to break down glycine. It can also use free dihydrolipoate, dihydrolipoami...(NADH); lipoamide reductase; lipoamide reductase (NADH); lipoate dehydrogenase; lipoic acid dehydrogenase; lipoyl dehydrogenase; protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase. Enzyme Commission Number: EC 1.8.1.4. CAS No. 9001-18-7. Diaphorase. Mole weight: ca. 110,000. Activity: >150 U/mg protein. Storage: Store at -20°C. Form: Lyophilized. Source: E. coli. LDP-Glc; LDP-Val; dehydrolipoate dehydrogenase; diaphorase; dihydrolipoamide dehydrogenase; dihydrolipoamide:NAD+ oxidoreductase; dihydrolipoic dehydrogenase; dihydrothioctic dehydrogenase; lipoamide dehydrogenase (NADH); lipoamide oxidoreductase (NADH); lipoamide reductase; lipoamide reductase (NADH); lipoate d | |
| Diaphorase from microorganism | Diaphorase from microorganism. Better stability and reactivity than dia-187. Group: Enzymes. Synonyms: dehydrolipoate dehydrogenase; diaphorase; dihydrolipoamide dehydrogenase; dihydrolipoamide:NAD+ oxidoreductase; dihydrolipoic dehydrogenase; dihydrothioctic dehydrogenase; lipoamide dehydrogenase (NADH); lipoamide oxidoreductase (NADH); lipoamide reductase; lipoamide reductase (NADH); lipoate dehydrogenase; lipoic acid dehydrogenase; lipoyl dehydrogenase; dihydrolipoyl dehydrogenase; Lipoamide Dehydrogenase. Enzyme Commission Number: EC 1.6.99.-. Diaphorase. Source: Microorganism. dehydrolipoate dehydrogenase; diaphorase; dihydrolipoamide dehydrogenase; dihydrolipoamide:NAD+ oxidoreductase; dihydrolipoic dehydrogenase; dihydrothioctic dehydrogenase; lipoamide dehydrogenase (NADH); lipoamide oxidoreductase (NADH); lipoamide reductase; lipoamide reductase (NADH); lipoate dehydrogenase; lipoic acid dehydrogenase; lipoyl dehydrogenase; dihydrolipoyl dehydrogenase; EC 1.8.1.4; 9001-18-7; Lipoamide Dehydrogenase. Cat No: DIA-275. | |
| dihydrolipoyl dehydrogenase | A flavoprotein (FAD). A component of the multienzyme 2-oxo-acid dehydrogenase complexes. In the pyruvate dehydrogenase complex, it binds to the core of EC 2.3.1.12, dihydrolipoyllysine-residue acetyltransferase, and catalyses oxidation of its dihydrolipoyl groups. It plays a similar role in the oxoglutarate and 3-methyl-2-oxobutanoate dehydrogenase complexes. Another substrate is the dihydrolipoyl group in the H-protein of the glycine-cleavage system (click here for diagram), in which it acts, together with EC 1.4.4.2, glycine dehydrogenase (decarboxylating), and EC 2.1.2.10, aminomethyltransferase, to break down glycine. It can also use free dihydrolipoate, dihydrolipoamide or...tase (NADH); lipoamide reductase; lipoamide reductase (NADH); lipoate dehydrogenase; lipoic acid dehydrogenase; lipoyl dehydrogenase; protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase. Enzyme Commission Number: EC 1.8.1.4. CAS No. 9001-18-7. Diaphorase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1648; dihydrolipoyl dehydrogenase; EC 1.8.1.4; 9001-18-7; LDP-Glc; LDP-Val; dehydrolipoate dehydrogenase; diaphorase; dihydrolipoamide dehydrogenase; dihydrolipoamide:NAD+ oxidoreductase; dihydrolipoic dehydrogenase; dihydrothioctic dehydrogenase; lipoamide dehydrogenase (NADH); lipoamide oxido | |
| dihydrolipoyllysine-residue acetyltransferase | A multimer (24-mer or 60-mer, depending on the source) of this enzyme forms the core of the pyruvate dehydrogenase multienzyme complex, and binds tightly both EC 1.2.4.1, pyruvate dehydrogenase (acetyl-transferring) and EC 1.8.1.4, dihydrolipoyl dehydrogenase. The lipoyl group of this enzyme is reductively acetylated by EC 1.2.4.1, and the only observed direction catalysed by EC 2.3.1.12 is that where the acetyl group is passed to coenzyme A. Group: Enzymes. Synonyms: acetyl-CoA:dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase; d. Enzyme Commission Number: EC 2.3.1.12. CAS No. 9032-29-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2058; dihydrolipoyllysine-residue acetyltransferase; EC 2.3.1.12; 9032-29-5; acetyl-CoA:dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase; dihydrolipoate acetyltransferase; dihydrolipoic transacetylase; dihydrolipoyl acetyltransferase; lipoate acetyltransferase; lipoate transacetylase; lipoic acetyltransferase; lipoic acid acetyltransferase; lipoic transacetylase; lipoylacetyltransferase; thioltransacetylase A; transacetylase X; enzyme-dihydrolipoyllysine:acetyl-CoA S-acetyltransferase; acetyl-CoA:enzyme 6-N-(dihydrolipoyl)lysine S-acetyltransferase. Cat No: EXWM-2058. | |
| DL-Thioctic acid | Lipoic acid is a very excellent natural antioxidant, with free radical scavenging effect, its ability to remove free radicals is more than 100 times that of vitamin C, especially suitable for anti-aging products. It has the effect of chelating metal ions, can bind to copper ions in tyrosinase, is a competitive inhibitor of tyrosinase, and has good whitening effect. However, lipoic acid has the problems of low solubility, poor stability and significant odor, which limits its application in cosmetics. The shortcomings of lipoic acid can be solved by supramolecular inclusion technology. It can be widely used in anti-aging, wrinkle removal, whitening, spot lightening, anti-inflammatory and anti-sensitivity, acne treatment, scar reduction, damage repair and other products, and it is compatible with lotion cream formula, gel formula and water formula. Synonyms: Thioctic acid; alpha-Lipoic acid; (+/-)-2-dithiolane-3-pentanoic acid; 1,2-Dithiolane-3-pentanoic acid; (RS)-Lipoic acid; (RS)-α-Lipoic acid; 5-(1,2-Dithiolan-3-yl)pentanoic acid. Grade: ≥98%. CAS No. 1077-28-7. Molecular formula: C8H14O2S2. Mole weight: 206.32. | |
| Lipoamide | Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide. CAS No. 940-69-2. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B1142. | |
| Lipoamide-PEG-Biotin, MW 1K-5K | Lipoamide-PEG-Biotin, MW 1,000 is a lipoic acid polyPEG which can bind to metallic surface through disulfide bond. The PEG derivative can be used for biotinylation due to its strong binding with avidin/streptavidin. Please contact us for GMP-grade inquiries. | |
| lipoate-protein ligase | Requires Mg2+. This enzyme participates in lipoate salvage, and is responsible for lipoylation in the presence of exogenous lipoic acid. The enzyme attaches lipoic acid to the lipoyl domains of certain key enzymes involved in oxidative metabolism, including pyruvate dehydrogenase (E2 domain), 2-oxoglutarate dehydrogenase (E2 domain), the branched-chain 2-oxoacid dehydrogenases and the glycine cleavage system (H protein). Lipoylation is essential for the function of these enzymes. The enzyme can also use octanoate instead of lipoate. Group: Enzymes. Synonyms: lplA (gene name); lplJ (gene name); lipoate protein ligase; lipoate-protein ligase A; LPL; LPL-B. Enzyme Commission Number: EC 6.3.1.20. CAS No. 144114-18-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5723; lipoate-protein ligase; EC 6.3.1.20; 144114-18-1; lplA (gene name); lplJ (gene name); lipoate protein ligase; lipoate-protein ligase A; LPL; LPL-B. Cat No: EXWM-5723. | |
| lipoyl amidotransferase | In the bacterium Listeria monocytogenes the enzyme takes part in a pathway for scavenging of lipoic acid. The enzyme is bound to 2-oxo-acid dehydrogenases such as the pyruvate dehydrogenase complex, where it transfers the lipoyl moiety from lipoyl-[glycine cleavage system H] to the E2 subunits of the complexes. Group: Enzymes. Synonyms: LipL (gene name, ambiguous). Enzyme Commission Number: EC 2.3.1.200. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2145; lipoyl amidotransferase; EC 2.3.1.200; LipL (gene name, ambiguous). Cat No: EXWM-2145. | |
| lipoyl synthase | This enzyme is a member of the 'AdoMet radical' (radical SAM) family, all members of which produce the 5'-deoxyadenosin-5'-yl radical and methionine from AdoMet [i.e. S-adenosylmethionine, or S-(5'-deoxyadenosin-5'-yl)methionine], by the addition of an electron from an iron-sulfur centre. The radical is converted into 5'-deoxyadenosine when it abstracts a hydrogen atom from C-6 and C-8, leaving reactive radicals at these positions so that they can add sulfur, with inversion of configuration. This enzyme catalyses the final step in the de-novo biosynthesis of the lipoyl cofactor, with the other enzyme involved being EC 2.3.1.181, lipoyl(octanoyl) transferase. Lipoylation is essential ...pathway involves EC 2.7.7.63, lipoate-protein ligase, which can lipoylate apoproteins using exogenous lipoic acid (or its analogues). Group: Enzymes. Synonyms: LS; LipA; lipoate synthase; protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase; protein N6-(octanoyl)lysine:sulfur sulfurtransferase. Enzyme Commission Number: EC 2.8.1.8. CAS No. 189398-80-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3366; lipoyl synthase; EC 2.8.1.8; 189398-80-9; LS; LipA; lipoate synthase; protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase; protein N6-(octanoyl)lysine:sulfur sulfurtransferase. Cat No: EXWM-3366. | |
| Native Clostridium kluyveri Diaphorase | Native Clostridium kluyveri Diaphorase. Applications: Diaphorase from clostridium kluyveri, or lipoyl dehydrogenase, has been used in a study to assess the protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism. lipoyl dehydrogenase has also been used in a study to investigate the redox regulation of tyrosine nitration and 3-nitrotyrosine reduction by antioxidants. Group: Enzymes. Synonyms: dehydrolipoate dehydrogenase; diaphorase; dihydrolipoamide dehydrogenase; dihydrolipoamide:NAD+ oxidoreductase; dihydrolipoic dehydrogenase; dihydrothioctic dehydrogenase; lipoamide dehydrogenase (NADH); lipoamide oxidoreductase (NADH); lipoamide reductase; lipo. Enzyme Commission Number: EC 1.8.1.4. CAS No. 9001-18-7. Diaphorase. Activity: 3.0-20.0 units/mg protein (biuret). Storage: Store at -20°C. Form: Lyophilized powder. Source: Clostridium kluyveri. dehydrolipoate dehydrogenase; diaphorase; dihydrolipoamide dehydrogenase; dihydrolipoamide:NAD+ oxidoreductase; dihydrolipoic dehydrogenase; dihydrothioctic dehydrogenase; lipoamide dehydrogenase (NADH); lipoamide oxidoreductase (NADH); lipoamide reductase; lipoamide reductase (NADH); lipoate dehydrogenase; lipoic acid dehydrogenase; lipoyl dehydrogenase; dihydrolipoyl dehydrogenase; EC 1.8.1.4; 9001-18-7; Lipoamide Dehydrogenase. Cat No: NATE-0875. | |
| Native Escherichia coli Thioredoxin Reductase | Thioredoxin reductase (TrxR) is an NADPH-dependent oxidoreductase containing one FAD per subunit that reduces the active site disulfide in oxidised thioredoxin (Trx). The molecular weight of the isozymes from mammalian sources vary between 55-67 kDa as compared with 35 kDa in prokaryotes, plants or yeast. The substrate specificity of the mammalian enzyme is much broader than the prokaryotic enzyme reducing both mammalian and E. coli thioredoxins as well as well as non-disulfide substrates such selenite, lipoic acids, lipid hydroperoxides and hydrogen peroxide. Applications: Thioredoxin reductase from escherichia coli can be used in peroxidase-coupled thioredoxin system assay for assessing the peroxidase activitiy of cys-based thiol peroxidases. the product was used for determining the enzymatic activity of his6-ahp1p. Group: Enzymes. Synonyms: NADP-thioredoxi. Enzyme Commission Number: EC 1.8.1.9. CAS No. 9074-14-0. TrxR. Activity: >25 units/mg protein (Bradford). Storage: 2-8°C. Form: ammonium sulfate suspension; Suspension in 3.6 M (NH4)2SO4 containing 30 mM potassium phosphate buffer, pH 7.5, and 2 mM EDTA. Source: Escherichia coli. NADP-thioredoxin reductase; NADPH-thioredoxin reductase; thioredoxin reductase (NADPH); NADPH2:oxidized thioredoxin oxidoreductase; thioredoxin-disulfide reductase; EC 1.8.1.9; TrxR. Cat No: NATE-0718. | |
| Native Rat Thioredoxin Reductase | Thioredoxin reductase (TrxR) is an NADPH-dependent oxidoreductase containing one FAD per subunit that reduces the active site disulfide in oxidised thioredoxin (Trx). The molecular weight of the isozymes from mammalian sources vary between 55-67 kDa as compared with 35 kDa in prokaryotes, plants or yeast. The substrate specificity of the mammalian enzyme is much broader than the prokaryotic enzyme reducing both mammalian and E. coli thioredoxins as well as well as non-disulfide substrates such selenite, lipoic acids, lipid hydroperoxides and hydrogen peroxide. Applications: Thioredoxin reductase from rat liver can be used for studying the uptake and reduction of a-lipoic acid... NADP-thioredoxin reductase; NADPH-thioredoxin reductase; thioredoxin reductase (NADPH); NADPH2:oxidized thioredoxin oxidoreductase; thioredoxin-disulfide reductase; EC 1.8.1.9; TrxR; 9074-14-0. Enzyme Commission Number: EC 1.8.1.9. CAS No. 9074-14-0. TrxR. Activity: > 100 units/mg protein (Bradford). Storage: -20°C. Form: buffered aqueous glycerol solution; Solution in 50 mM Tris-HCl, pH 7.5, 300 mM NaCl, 1 mM EDTA, and 10% glycerol. Source: Rat liver. Species: Rat. NADP-thioredoxin reductase; NADPH-thioredoxin reductase; thioredoxin reductase (NADPH); NADPH2:oxidized thioredoxin oxidoreductase; thioredoxin-disulfide reductase; EC 1.8.1.9; TrxR; 9074-14-0. Cat No: NATE-0713. | |
| (R)-(+)-α-Lipoic Amide | (R)-(+)-α-Lipoic Amide is amide form of rac α-Lipoic Acid (L468725) and is useful for the prevention of primary hypertension. Group: Biochemicals. Grades: Highly Purified. CAS No. 122999-10-4. Pack Sizes: 10mg, 100mg. Molecular Formula: C8H15NOS2, Molecular Weight: 205.34. US Biological Life Sciences. | Worldwide |
| (S)-Thioctic acid | (S)-Thioctic acid ((S)-lipoic acid; (S)-5-(1,2-Dithiolan-3-yl)pentanoic acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (S)-lipoic acid; (S)-5-(1,2-Dithiolan-3-yl)pentanoic acid. CAS No. 1077-27-6. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-W014590. | |
| Thioctic acid | Supplement. CAS No. 1077-28-7. Categories: dl- alpha-lipoic acid, 5-(1,2-dithiolan-3-yl)pentanoic acid, 1. |  US, Austria, Lithuania |
| Thioctic acid | Thioctic acid. Uses: For analytical and research use. Group: Pharma & vet compounds & metabolites; pharma & vet compounds & metabolites; api standards; european pharmacopoeia (ph. eur.); pharmaceutical toxicology; pharmacopoeial standards. Alternative Names: 6,8-Thioctic acid, DL-6,8-Thioctic acid, Espa-lipon, Liposan, 1,2-Dithiolane-3-valeric acid, (+/-)-1,2-Dithiolane-3-pentanoic acid, 6-Thioctic acid, DL-alpha-Lipoic acid, 5-(1,2-Dithiolan-3-yl)valeric acid, DL-Thioctic acid, NSC 628502, Tioctidasi, DL-6-Thioctic acid, Tioctidasi acetate replacing factor, (RS)-alpha-Lipoic acid, Lipothion, NSC 90788, dl-Thioctic acid, Protogen A, (+/-)-1,2-Dithiolane-3-valeric acid, (+/-)-alpha-Lipoic acid, alpha-Liponic acid, Biletan, Tioctacid, Thioctacid,Thioctic Acid, 5-(1,2-Dithiolan-3-yl)pentanoic acid, Pyruvate oxidation factor, dl-Lipoic acid, (RS)-Lipoic acid, (+/-)-Lipoic acid, Thioctsan, Thiotacid, Alipure, 1,2-Dithiolane-3-pentanoic acid, (+/-)-Thioctic acid, Thioctic acid. CAS No. 1077-28-7. IUPAC Name: 5-(dithiolan-3-yl)pentanoic acid. Molecular formula: C8H14O2S2. Mole weight: 206.33. Catalog: APS1077287. SMILES: OC(=O)CCCCC1CCSS1. Format: Neat. | |
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