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25g Pack Size. Group: Bioactive Small Molecules. Formula: C24H36O5. CAS No. 75330-75-5. Prepack ID 13200962-25g. Molecular Weight 404.54. See USA prepack pricing.
Lovastatin
5g Pack Size. Group: Bioactive Small Molecules. Formula: C24H36O5. CAS No. 75330-75-5. Prepack ID 13200962-5g. Molecular Weight 404.54. See USA prepack pricing.
Lovastatin
Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol. Uses: Scientific research. Group: Natural products. Alternative Names: Mevinolin. CAS No. 75330-75-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0504.
Labelled Lovastatin an antihypercholesterolem ic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Lovastatin-d3 Hydroxy Acid Sodium Salt (Lovastatin-d3 Sodium Salt, MB 530B-d3)
A labeled metabolite of Lovastatin. Group: Biochemicals. Alternative Names: Lovastatin-d3 Sodium Salt;MB 530B-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Lovastatin-D9
Lovastatin-D9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1002346-03-3. Molecular Formula: C24H27D9O5. Mole Weight: 413.6. Catalog: APB1002346033.
An intermediate used for synthesis of Simvastatin precursor. Group: Biochemicals. Alternative Names: (4R, 6R) -4- [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] -6- [2- [ (1S, 2S, 6R, 8S, 8aR) -1, 2, 6, 7, 8, 8a-hexahydro-8-hydroxy-2, 6-dimethyl-1-naphthalenyl] ethyl] tetrahydro-2H-pyran-2-one. Grades: Highly Purified. CAS No. 79902-31-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Lovastatin EP Impurity A (Mevastatin)
Lovastatin EP Impurity A (Mevastatin). Uses: For analytical and research use. Group: Impurity standards. CAS No. 73573-88-3. Molecular Formula: C23H34O5. Mole Weight: 390.52. Catalog: APB73573883.
Lovastatin EP Impurity B
Lovastatin EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 75225-51-3. Molecular Formula: C24H38O6. Mole Weight: 422.56. Catalog: APB75225513.
Lovastatin EP Impurity B-D3 Sodium Salt
Lovastatin EP Impurity B-D3 Sodium Salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1279029-75-2. Molecular Formula: C24H34D3NaO6. Mole Weight: 447.56. Catalog: APB1279029752.
Lovastatin EP Impurity B Sodium Salt
Lovastatin EP Impurity B Sodium Salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 75225-50-2. Molecular Formula: C24H37NaO6. Mole Weight: 444.54. Catalog: APB75225502.
Lovastatin EP Impurity C
Lovastatin EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 109273-98-5. Molecular Formula: C24H34O4. Mole Weight: 386.53. Catalog: APB109273985.
Lovastatin EP Impurity D
Lovastatin EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 149756-62-7. Molecular Formula: C48H72O10. Mole Weight: 809.09. Catalog: APB149756627.
Lovastatin EP Impurity E
Lovastatin EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 77517-29-4. Molecular Formula: C24H38O5. Mole Weight: 406.56. Catalog: APB77517294.
Lovastatin EP Impurity F
Lovastatin EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1048973-04-1. Molecular Formula: C24H34O5. Mole Weight: 402.53. Catalog: APB1048973041.
Lovastatin Hydroxy Acid
Lovastatin Hydroxy Acid is an active metabolite of Lovastatin. Lovastatin is a HMG-CoA reductase inhibitor isolated from cultures of Aspergillus terreus. HMG-CoA reductase plays a role in cholesterol biosynthesis. Synonyms: Lovastatin acid; Mevinolinic acid; Monacolinic K acid; MSD 803 acid; MSD 803 free acid; UNII-5CLV35Y90C; (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid. CAS No. 75225-51-3. Molecular formula: C24H38O6. Mole weight: 422.562.
Lovastatin hydroxy acid, sodium salt
Lovastatin hydroxy acid, sodium salt. Group: Biochemicals. Alternative Names: Lovastatin sodium salt; MB 530B; Mevinolinic acid. Grades: Highly Purified. CAS No. 75225-50-2. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C24H37NaO6. US Biological Life Sciences.
Worldwide
Lovastatin Hydroxy Acid, Sodium Salt
Lovastatin Hydroxy Acid, Sodium Salt is a metabolite of Lovastatin. Synonyms: Lovastatin Sodium Salt; MB 530B; Mevinolinic Acid. Grades: > 95%. CAS No. 75225-50-2. Molecular formula: C24H37O6Na. Mole weight: 444.54.
Lovastatin Hydroxy Acid, Sodium Salt (Lovastatin Sodium Salt, MB 530B)
A metabolite of Lovastatin. Group: Biochemicals. Alternative Names: Lovastatin Sodium Salt; MB 530B. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM, used for lowering cholesterol (hypolipidemic agent). Uses: Antioxidant / antihypercholesterolemic / antiarrhythmic. Synonyms: Mevacor; Monacolin K; Altoprev; MK 803; MK-803; MK803; Monacolin K; QAB149; MSD 803; Simvastatin EP Impurity E; Simvastatin USP Related Compound E; Desmethyl Simvastatin. Grades: >98%. CAS No. 75330-75-5. Molecular formula: C24H36O5. Mole weight: 404.54.
Lovastatin (MK-803, Lovalip, Mevacor, Mevinacor)
An antihypercholesterolem ic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase. Group: Biochemicals. Alternative Names: MK-803, Lovalip, Mevacor, Mevinacor. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
lovastatin nonaketide synthase
This fungal enzyme system comprises a multi-functional polyketide synthase (PKS) and an enoyl reductase. The PKS catalyses many of the chain building reactions of EC 2.3.1.85, fatty-acid synthase, as well as a reductive methylation and a Diels-Alder reaction, while the reductase is responsible for three enoyl reductions that are necessary for dihydromonacolin L acid production. Group: Enzymes. Synonyms: LNKS; LovB; LovC; acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing). Enzyme Commission Number: EC 2.3.1.161. CAS No. 235426-97-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2101; lovastatin nonaketide synthase; EC 2.3.1.161; 235426-97-8; LNKS; LovB; LovC; acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing). Cat No: EXWM-2101.
Lovastatin (Simvastatin EP IMpurity E)
Lovastatin (Simvastatin EP IMpurity E). Uses: For analytical and research use. Group: Impurity standards. CAS No. 75330-75-5. Molecular Formula: C24H36O5. Mole Weight: 404.55. Catalog: APB75330755.
4a,5-Dihydro lovastatin
4a,5-Dihydro lovastatin. Group: Biochemicals. Alternative Names: (2S)-2-Methylbutanoic acid (1S,3S,4aR,7S,8S,8aS)-1,2,3,4,4a,7,8,8a-octahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester; (+)-Dihydromevinolin; Dihydrolovastatin. Grades: Highly Purified. CAS No. 77517-29-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C24H38O5. US Biological Life Sciences.
Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC 50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81189-92-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-126237.
Dihydromonacolin L acid is synthesized while bound to an acyl-carrier protein domain of the lovastatin nonaketide synthase (EC 2.3.1.161). Since that enzyme lacks a thioesterase domain, release of the dihydromonacolin L acid moiety from the polyketide synthase requires this dedicated enzyme. Group: Enzymes. Synonyms: LovG. Enzyme Commission Number: EC 3.1.2.31. GUSB. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3565; dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase; EC 3.1.2.31; LovG. Cat No: EXWM-3565.
Epi Lovastatin
Lovastatin impurity; an antihypercholesterolem ic compound. Group: Biochemicals. Alternative Names: (2R)-. Grades: Highly Purified. CAS No. 79952-44-6. Pack Sizes: 1mg. US Biological Life Sciences.
1, 5-Cyclooctadiene (pyridine) (tri cyclohexylphosphine) iridium (I) Hexafluorophosphate is a catalyst that is used in the synthesis of 4α,5-Dihydro Simvastatin (D450010). 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Grades: Highly Purified. CAS No. 64536-78-3. Pack Sizes: 50mg, 100mg. Molecular Formula: C31H48F6IrNP2. US Biological Life Sciences.
Worldwide
2,2-Dimethylbutanoyl Chloride
2,2-Dimethylbutanoyl chloride is a reagent that is used in the synthesis of 4α,5-Dihydro Simvastatin (D450010). 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Grades: Highly Purified. CAS No. 5856-77-9. Pack Sizes: 1g, 5g. Molecular Formula: C6H11ClO. US Biological Life Sciences.
Worldwide
2'-Ethyl Simvastatin
2'-Ethyl Simvastatin is an impurity of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Grades: Highly Purified. CAS No. 79902-42-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H34O5, Molecular Weight: 390.51. US Biological Life Sciences.
Worldwide
2'-Ethyl Simvastatin-d6
Isotope labelled 2'-Ethyl Simvastatin is an impurity of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H28D6O5, Molecular Weight: 396.55. US Biological Life Sciences.
Worldwide
2-methylbutanoate polyketide synthase
This polyketide synthase enzyme forms the (S)-2-methylbutanoate side chain during lovastatin biosynthesis by the filamentous fungus Aspergillus terreus. The overall reaction comprises a single condensation reaction followed by α-methylation, β-ketoreduction, dehydration, and α,β enoyl reduction. Group: Enzymes. Synonyms: LovF. Enzyme Commission Number: EC 2.3.1.244. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2193; 2-methylbutanoate polyketide synthase; EC 2.3.1.244; LovF. Cat No: EXWM-2193.
An intermediate in the synthesis of labeled Lovastatin an antihypercholesterolem ic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Dihydromevinolin
Dihydromevinolin is an impurity in Lovastatin bulk drug. It is produced by the strain of Aspergollus terreus. Synonyms: 4a,5-Dihydro Lovastatin; (2S)-2-Methylbutanoic Acid (1S,3S,4aR,7S,8S,8aS)-1,2,3,4,4a,7,8,8a-Octahydro- 3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; (+)-Dihydromevinolin; Dihydrolovastatin; Dihydromevinol. Grades: > 95%. CAS No. 77517-29-4. Molecular formula: C24H38O5. Mole weight: 406.56.
γ-Hydroxymevinolin
γ-Hydroxymevinolin is a homolog of lovastatin produced by Aspergillus terreus MF-4833. It has anti-fungal, cholesterol and blood lipid-lowering activities. Synonyms: 3''-Hydroxylovastatin. CAS No. 125638-72-4. Molecular formula: C24H36O6. Mole weight: 420.54.
monacolin J acid methylbutanoate transferase
The enzyme catalyses the ultimate reaction in the lovastatin biosynthesis pathway of the filamentous fungus Aspergillus terreus. Group: Enzymes. Synonyms: LovD. Enzyme Commission Number: EC 2.3.1.238. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2186; monacolin J acid methylbutanoate transferase; EC 2.3.1.238; LovD. Cat No: EXWM-2186.
Pravastatin Sodium Salt
Pravastatin sodium is the sodium salt of pravastatin, a ring- opened member of the statin family. Pravastatin is produced biosynthetically from compactin (mevastatin) by a number of micro-organisms, notablyAbsidia, Cunninghamella, Syncephalastrum, Nocardia or Streptomyces. Typically, statins like compactin, lovastatin and simvastatin possess a b-hydroxy lactone ring which is a pro-drug for the readily ring-opened dihydroxyacid generally regarded as the active HMG-CoA inhibitor. Importantly, the free carboxylic acid enables pravastatin to be freely water soluble within biological pH ranges. Pravastatin is used therapeutically to reduce LDL cholesterol. Group: Biochemicals. Grades: Highly Purified. CAS No. 81131-70-6. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Simvastatin
A competitive inhibitor of HMG-CoA reductase. A synthetic analog of lovastatin. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Alternative Names: 2,2-Dimethylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; (+)-Simvastatin; Cholestat; Lipex; Novo-Simvastatin; Simvotin; Sinvacor; Statin; Zorced; MK-733, Synvinolin, BRN 4768037; Zocor, Liponorm. Grades: Highly Purified. CAS No. 79902-63-9. Pack Sizes: 25g, 50g, 100g, 250g. Molecular Formula: C??H??O?, Molecular Weight: 418.57. US Biological Life Sciences.
Worldwide
Simvastatin-d6
Deuterated Simvastatin, a competitive inhibitor of HMG-CoA reductase. A deuterated synthetic analog of lovastatin. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Alternative Names: 2,2-(Dimethyl-d6)butanoic Acid(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; (+)-Simvastatin-d6; Cholestat-d6; Lipex-d6; Novo-Simvastatin-d6; Simvotin-d6; Sinvacor-d6; Statin-d6; Zocor-d6; Zorced-d6. Grades: Highly Purified. CAS No. 1002347-71-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C??H??D?O?, Molecular Weight: 424.6. US Biological Life Sciences.
Worldwide
Simvastatin EP Impurity F
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Simvastatin USP Related Compound F; epi-Lovastatin; Lovastatin epimer; (2R)-2-Methylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester. Grades: 95%. CAS No. 79952-44-6. Molecular formula: C24H36O5. Mole weight: 404.55.
Simvastatin Impurity K (4alpha,5-Dihydro Simvastatin)
4alpha,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin, a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Alternative Names: (1S,3S,4aR,7S,8S,8aS)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl 2,2-dimethylbutanoate; Simvastatin Impurity K. Grades: Highly Purified. Pack Sizes: 500ug, 1mg, 5mg. Molecular Formula: C25H40O5. US Biological Life Sciences.
Worldwide
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