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| Product | Description | |
|---|---|---|
| Mellitic acid | 1g Pack Size. Group: Building Blocks, Organics. Formula: C12H6O12. CAS No. 517-60-2. Prepack ID 90027024-1g. Molecular Weight 342.17. See USA prepack pricing. |  |
| 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine | 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: 2,2,2-Trifluoroacetic Acid 2-(2-Chloroacetyl)hydrazide; N'-(chloroacetyl)-2,2,2-trifluoroacetohydrazide. Grade: >95%. CAS No. 762240-99-3. Molecular formula: C4H4ClF3N2O2. Mole weight: 204.53. |  |
| 2,4,5-Trifluoro-L-β-homophenylalanine hydrochloride | 2,4,5-Trifluoro-L-β-homophenylalanine hydrochloride is used as a reagent in the synthesis of valuable β-amylalkyl-β-amino acid enantiomers. It is also an impurity of Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Synonyms: (S)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid hydrochloride. Grade: 95%. CAS No. 1217809-78-3. Molecular formula: C10H11ClF3NO2. Mole weight: 269.65. | |
| 2,4-Difluorophenylacetic acid | 2,4-Difluorophenylacetic acid is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Synonyms: 2-(2,4-difluorophenyl)acetic acid. Grade: 99%. CAS No. 81228-09-3. Molecular formula: C8H6F2O2. Mole weight: 172.13. | |
| 2-Acetamido-3-O-acetyl-4,6-O-benzylidene-N-(tert-butoxycarbonyl)-1,2,5-trideoxy-1,5-imino-D-glucitol | 2-Acetamido-3-O-acetyl-4,6-O-benzylidene-N-(tert-butoxycarbonyl)-1,2,5-trideoxy-1,5-imino-D-glucitol is an intricate compound renowned for its formidable inhibitory prowess against the enzyme glucosidase. This compound holds immense promise in the research of combatting type 2 diabetes mellitus and an array of metabolic maladies. Synonyms: 5H-1,3-Dioxino[5,4-b]pyridine-5-carboxylic acid, 7-(acetylamino)-8-(acetyloxy)hexahydro-2-phenyl-, 1,1-dimethylethyl ester, (4aR,7S,8R,8aR)-. CAS No. 1221795-92-1. Molecular formula: C22H30N2O7. Mole weight: 434.48. | |
| 2-Carboxy-3,4,6-trifluorobenzeneacetic acid | An impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin Impurity 120. Grade: ≥95%. CAS No. 2428591-91-5. Molecular formula: C9H5F3O4. Mole weight: 234.13. | |
| 2-Desisopropyl-2-phenyl Repaglinide (Repaglinide Impurity) | An impurity of Repaglinide. Repaglinide is an antidiabetic drug. Repaglinide is an oral medication used in addition to diet and exercise for blood sugar control in type 2 diabetes mellitus. Synonyms: 2-Ethoxy-4-[2-oxo-2-[[2-phenyl-1-[2-(1-piperidinyl)phenyl]ethyl]amino]ethyl]benzoic Acid. Grade: > 95%. CAS No. 107362-12-9. Molecular formula: C30H34N2O4. Mole weight: 486.62. | |
| 2-Despiperidyl-2-(5-Carboxypentylamine Repaglinide) (M2 Metabolite) | A metabolite of Repaglinide. Repaglinide is an antidiabetic drug. Repaglinide is an oral medication used in addition to diet and exercise for blood sugar control in type 2 diabetes mellitus. Synonyms: 4-[2-[[1-[2-[(4-Carboxybutyl)amino]phenyl]-3-methylbutyl]amino]-2-oxoethyl]-2-ethoxybenzoic Acid; Repaglinide M2 metabolite. Grade: > 95%. CAS No. 874908-12-0. Molecular formula: C27H36N2O6. Mole weight: 484.6. | |
| 2-Ethylphenol-[d10] | 2-Ethylphenol-[d10] is the labelled analogue of 2-Ethylphenol, which is used as a reagent for the synthesis of phenoxyacetic acid derivatives as novel free fatty acid receptor 1 agonists for the treatment of diabetes mellitus. Synonyms: 2-Ethylphenol D10; 1-Ethyl-2-hydroxybenzene-d10; NSC 10112-d10; Phlorol-d10; o-Ethylphenol-d10; o-Hydroxyethylbenzene-d10. Grade: 98%; 99% atom D. CAS No. 721429-63-6. Molecular formula: C8D10O. Mole weight: 132.23. | |
| 2-Keto-D-galactonic acid | 2-Keto-D-galactonic acid is a key compound in the biomedical sphere, assuming a pivotal role in research of conditions like hypertriglyceridemia, diabetes mellitus, and galactosemia. Synonyms: (3S,4S,5R)-3,4,5,6-tetrahydroxy-2-keto-hexanoic acid; L-Xylo-2-Hexulosonic Acid Hydrate; SCHEMBL5807374; AKOS015894428; AC-11922; C03342; (3S,4S,5R)-3,4,5,6-tetrahydroxy-2-oxo-hexanoic acid. CAS No. 16722-49-9. Molecular formula: C6H10O7. Mole weight: 194.14. | |
| 2- methyl enecyclopropaneacetic Acid | 2- methyl enecyclopropaneacetic Acid is an intermediate in the preparation of novel agents for the therapy of non-insulin dependent diabetes mellitus. Group: Biochemicals. Grades: Highly Purified. CAS No. 1073-00-3. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C6H8O2. US Biological Life Sciences. |  Worldwide |
| 3,4:5,6-Di-O-isopropylidene-L-gulonic acid methyl ester | 3,4:5,6-Di-O-isopropylidene-L-gulonic acid methyl ester, a compound of utmost importance within the realm of biomedical research and pharmaceutical progression, serves as a beacon of potential in the treatment and understanding of a myriad of afflictions. With its multifaceted capabilities, it proudly contributes to combating the likes of cardiovascular disorders, diabetes mellitus, and immune-related conditions. Molecular formula: C13H22O7. Mole weight: 290.31. | |
| 3,4-Difluorophenylacetic acid | 3,4-Difluorophenylacetic acid is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Synonyms: 2-(3,4-difluorophenyl)acetic acid. Grade: 99%. CAS No. 658-93-5. Molecular formula: C8H6F2O2. Mole weight: 172.13. | |
| 3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid hydrochloride | An impurity of Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Grade: 95%. CAS No. 1909337-07-0. Molecular formula: C10H11ClF3NO2. Mole weight: 269.65. | |
| 3-(((Benzyloxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid | 3-(((Benzyloxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Molecular formula: C18H16F3NO4. Mole weight: 367.32. | |
| 3-Ethoxy-4-ethoxycarbonyl phenylacetic acid | An intermediate of Repaglinide. Repaglinide is an antidiabetic drug. Repaglinide is an oral medication used in addition to diet and exercise for blood sugar control in type 2 diabetes mellitus. Synonyms: 3-Ethoxy-4-(ethoxycarbonyl)benzeneacetic Acid; [3-Ethoxy-4-(ethoxycarbonyl)phenyl]acetic Acid. Grade: > 95%. CAS No. 99469-99-5. Molecular formula: C13H16O5. Mole weight: 252.27. | |
| 3'-Hydroxy Repaglinide (Mixture of Diastereomers) | A metabolite of Repaglinide. Repaglinide is an antidiabetic drug. Repaglinide is an oral medication used in addition to diet and exercise for blood sugar control in type 2 diabetes mellitus. Synonyms: 2-Ethoxy-4-[2-[[1-[2-(3-hydroxy-1-piperidinyl)phenyl]-3-methylbutyl]amino]-2-oxoethyl]benzoic Acid. Grade: > 95%. CAS No. 874908-14-2. Molecular formula: C27H36N2O5. Mole weight: 468.6. | |
| 3-O-Acetyl-4-O-methyl-D-glucuronic acid | 3-O-Acetyl-4-O-methyl-D-glucuronic acid is a noteworthy chemical entity used in studying multifarious ailments like carcinoma, diabetes mellitus and inflammatory conditions. CAS No. 2892629-39-7. Molecular formula: C9H14O8. Mole weight: 250.20. | |
| (5-Hydroxy rosiglitazone)-b-D-glucuronide | (5-Hydroxy rosiglitazone)-b-D-glucuronide is a biochemical compound used as a metabolite marker in diabetes research. Specifically, it is associated with the study of type 2 diabetes mellitus as a breakdown product of rosiglitazone, an antidiabetic medication. Synonyms: 6-[6-({2-[4-Dioxo-thiazolindin-5-yl-methyl)-phenoxy]ethyl}-methyl-amino)-pyridin-3-yloxy]-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid. CAS No. 288853-59-8. Molecular formula: C24H27N3O10S. Mole weight: 549.55. | |
| 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) TFA | 8-Glycine-36-L-argininamide-7-36-Glucagon-like peptide 1 (Octodon degus) TFA is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2.TFA; L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-argininamide trifluoroacetic acid; 7-36-Glucagon-like peptide 1 (Octodon degus), 8-glycine-36-L-argininamide-, trifluoroacetate; Albiglutide TFA; [Gly8,Arg36]-GLP 1 (7-36) amide (Octodon degus) TFA. Grade: ≥95%. Molecular formula: C150H225F3N40O47. Mole weight: 3397.63. | |
| Adomeglivant | Adomeglivant has been found to be a glucagon receptor antagonist that could probably be effective for both type-I and type-II diabetes mellitus. Synonyms: Adomeglivant; LY-2409021; Adomeglivant [USAN]; UNII-74Z5ZL2KVG; LY2409021; LY 2409021; 3-[[4-[(1S)-1-[4-(4-tert-butylphenyl)-3,5-dimethylphenoxy]-4,4,4-trifluorobutyl]benzoyl]amino]propanoic acid. Grade: 98%. CAS No. 1488363-78-5. Molecular formula: C32H36F3NO4. Mole weight: 555.64. | |
| AS 1842856 | AS 1842856 is a potent and selective inhibitor of Forkhead box protein O1 transcription factor (FoxO1; IC50 = 33 nM). AS 1842856 reduces glucose production in dose manner via the inhibition of glucose-6 phosphatase and phosphoenolpyruvate carboxykinase mRNA levels in a rat hepatic cell line. AS 1842856 is promisingly to be a therapy of type 2 diabetes mellitus and obesity. Uses: Potential treatment of type 2 diabetes mellitus and obesity. Synonyms: AS1842856; AS-1842856; AS 1842856. 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid. Grade: 98%. CAS No. 836620-48-5. Molecular formula: C18H22FN3O3. Mole weight: 347.38. | |
| Benzyl b-D-glucopyranosiduronic acid | Benzyl b-D-glucopyranosiduronic acid is an innovative compound, unveiling immense prospects in research of glucose metabolism disorder, particularly diabetes mellitus. Synonyms: Benzyl Alcohol Glucuronide. CAS No. 5285-2-9. Molecular formula: C13H16O7. Mole weight: 284.26. | |
| Boc-2-fluoro-D-β-homophenylalanine | Boc-2-fluoro-D-β-homophenylalanine is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-3-((tert-butoxycarbonyl)amino)-4-(2-fluorophenyl)butanoic acid; Boc-D-β-HomoPhe(2-F)-OH; Boc-(R)-3-amino-4-(2-fluorophenyl)butyric acid. Grade: >98%. CAS No. 218608-98-1. Molecular formula: C15H20FNO4. Mole weight: 297.32. | |
| Boc-3,4-difluoro-D-beta-homophenylalanine | Boc-3,4-difluoro-D-beta-homophenylalanine is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Boc-(R)-3-amino-4-(3,4-difluoro-phenyl)-butyric acid; (R)-3-((tert-butoxycarbonyl)amino)-4-(3,4-difluorophenyl)butanoic acid. Grade: >90%. CAS No. 269396-59-0. Molecular formula: C15H19F2NO4. Mole weight: 315.31. | |
| CL-316243 sodium | CL-316243 is a highly selective β3-adrenoceptor agonist with EC50 value of 3 nM; > 10000-fold selective over β1 and β2 receptors. CL-316243 can restore the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice and enhance insulin-stimulated glucose disposal in nonobese rats. Preclical trials for the treatment of Obesity, Overactive bladder and Type 2 diabetes mellitus were discontinued. Uses: Obesity; overactive bladder; type 2 diabetes mellitus. Synonyms: CL-316243 sodium; CL 316243 sodium; CL316243 sodium; disodium; 5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate; BTA 243; HP 186; BTA243; HP186; BTA-243; HP-186. Grade: 98%. CAS No. 138908-40-4. Molecular formula: C20H18ClNNa2O7. Mole weight: 465.79. | |
| Dapagliflozin 3-O-β-D-Glucuronide | Dapagliflozin 3-O-β-D-Glucuronide is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3-O-β-D-glucopyranuronosyl-D-glucitol; D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3-O-β-D-glucopyranuronosyl-, (1S)-; (2S,3S,4S,5R,6R)-6-(((2S,3S,4R,5R,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; Dapagliflozin M-15 metabolite; Dapagliflozin 3-O-glucuronide. Grade: ≥95%. CAS No. 1351438-75-9. Molecular formula: C27H33ClO12. Mole weight: 585.00. | |
| Dapagliflozin Impurity 55 | Dapagliflozin Impurity 55 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 2-chloro-5-bromobenzoic acid chloride. Grade: >95%. CAS No. 21900-52-7. Molecular formula: C7H3BrCl2O. Mole weight: 253.91. | |
| Dutogliptin | Dutogliptin is a selective and orally active DPP4 inhibitor. It can improve glycaemic control in patients with type 2 diabetes. But phase III clinical trials for the treatment of type 2 diabetes were discontinued. Uses: Type 2 diabetes mellitus. Synonyms: PHX 1149; PHX1149; PHX-1149; (2R)-1-(((3R)-Pyrrolidin-3-ylamino)acetyl)pyrrolidin-2-yl)boronic acid; 890402-81-0 (tartrate salt). Grade: 98%. CAS No. 852329-66-9. Molecular formula: C10H20BN3O3. Mole weight: 241.10. | |
| Exenatide acetate | Exenatide acetate is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor with Ki value of 136 pM. It is a 39 amino acid peptide, which increases intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. It was first isolated from the venom of H. horridum and consequently synthesized. It stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1 receptor-dependent mechanism. It also stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma βTC-1 cells. It protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neurodegenerative diseases. It also has anxiolytic and anti-depressant effects and induces satiety. It is an incretin mimetic approved for type 2 diabetes mellitus treatment. It also has neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. Synonyms: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-, ac. Grade: >9 | |
| Fmoc-Lys(Pal-Glu-OtBu)-OH | Fmoc-Lys(Pal-Glu-OtBu)-OH is a non-cleavable ADC linker. It can also be used as an alkyl chain-based PROTAC linker. Uses: Fmoc-lys(pal-glu-otbu)-oh is a building block for the synthesis of liraglutide that is used to treat type 2 diabetes mellitus. fmoc-lys (pal-glu-otbu)-oh is a non-cleavable antibody-drug conjugates linker. it can also be used as an alkyl chain-based protac linker. Synonyms: (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-6-[[(4S)-4-(hexadecanoylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]amino]hexanoic acid; Fmoc-l-lys(palm-l-glu-otbu)-OH. CAS No. 1491158-62-3. Molecular formula: C46H69N3O8. Mole weight: 792. | |
| Fmoc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butyric Acid | Fmoc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butyric Acid is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: N-β-(9-Fluorenylmethoxycarbonyl)-2,4,5-trifluoro-D-β-homophenylalanine; (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid. Grade: >95%. CAS No. 1217818-53-5. Molecular formula: C25H20F3NO4. Mole weight: 455.43. | |
| Fructosyl-Amino Acid Oxidase from Corynebacterium sp., Recombinant | Fructosamines are formed when glucose is condensed amino group of amino acids or proteins. Fructosamine oxidases (FAOX) catalyze the oxidative deglycation of low molecular weight fructosamines. Fructosyl amino acid oxidase catalyzes the oxidation of the C-N bond linking the C1 of the fructosyl moiety and the nitrogen of the amino group of fructosyl amino acids. Enzyme commission (e.c.) 1.5.3.x, fructosyl amino acid oxidase [fructosyl-a-l-amino acid:oxygen oxidoreductase] is a flavoprotein that catalyzes the oxidation of fructosyl amino acids to form glucosone, amino acid and hydrogen peroxide. Applications: Fructosyl-amino acid oxidase can be used to detect the levels of glycated proteins, which are markers for diabetes mellitus. Group: Enzymes. Synonyms: Fructosyl-Amino Acid Oxidase. Fructosyl-amino acid oxidase. Mole weight: mol wt ~88 kDa by electrophoresis. Activity: > 0.45 units/mg protein. Storage: -20°C. Form: lyophilized powder. Source: E. coli. Species: Corynebacterium sp. Fructosyl-Amino Acid Oxidase. Cat No: NATE-0258. |  |
| GLP-1 receptor agonist 7 | GLP-1 receptor agonist 7 is a potent glucagon-like peptide-1 (GLP-1) agonist with potential to study GLP-1-related diseases, disorders and conditions, including diabetes mellitus. (Extracted from patent WO2021219019A1, compound 130b). Synonyms: 2-((4-((S)-3-(4-chloro-2-fluorophenyl)-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperidin-1-yl)methyl)-3-(((S)-oxetan-2-yl)methyl)-3H-imidazo[4,5-b]pyridine-5-carboxylic acid. CAS No. 2736447-04-2. Molecular formula: C31H30ClFN4O5. Mole weight: 593.05. | |
| Glucagon receptor antagonists-5 | Glucagon receptor antagonists-5 is a potent and orally bioavailable indazole-based glucagon receptor antagonist (Ki = 32?nM) with potential for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: (S)-3-(4-(1-(5-(2-Chloro-4-(trifluoromethyl)phenyl)-6-methyl-1H-indazol-1-yl)-3-methylbutyl)benzamido)propanoic acid; N-{4-[(1S)-1-{5-[2-Chloro-4-(trifluoromethyl)phenyl]-6-methyl-1H-indazol-1-yl}-3-methylbutyl]benzoyl}-β-alanine. Grade: ≥95%. CAS No. 2200274-63-9. Molecular formula: C30H29ClF3N3O3. Mole weight: 572.02. | |
| GRA Ex-25 | GRA Ex-25 is an orally active human glucagon receptor antagonist in a transgenic murine pharmacodynamic model, with IC50 of 56 and 55 nM for rat and human glucagon receptors, respectively. GCGR has evolved as an attractive therapeutic target for the treatment of type II diabetes mellitus. Synonyms: 3-(4-((1-(4-(tert-butyl)cyclohexyl)-3-(4-(trifluoromethoxy)phenyl)ureido)methyl)benzamido)propanoic acid; GRA Ex-25; GRA Ex 25; GRA Ex25; GRAEx-25; GRAEx 25; GRAEx25. CAS No. 307983-31-9. Molecular formula: C29H36F3N3O5. Mole weight: 563.61. | |
| GSK256073 | GSK256073 is a potent, selective and orally active GPR109A agonist and a long-lasting and non-flushing HCA2 full agonist with a pEC50 of 7.5 (human HCA2). GSK256073 acutely improves glucose homeostasis via inhibition of lipolysis and has the potential for the study of type 2 diabetes mellitus (T2DM)and dyslipidemia[1][2]. GPR109A: G-protein coupled receptor 109A; HCA2: hydroxy-carboxylic acid receptor 2. Uses: Scientific research. Group: Signaling pathways. CAS No. 862892-90-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119222. |  |
| GSK256073 | GSK256073 is a potent, selective and orally active G-protein coupled receptor 109A (GPR109A) agonist and a long-lasting and non-flushing hydroxy-carboxylic acid receptor 2 (HCA2) full agonist with a pEC50 of 7.5 for human HCA2. It acutely improves glucose homeostasis by inhibiting lipid breakdown and has the potential to study type 2 diabetes mellitus (T2DM) and dyslipidemia. Synonyms: 8-Chloro-3-pentyl-1H-purine-2,6(3H,7H)-dione; 1H-Purine-2,6-dione, 8-chloro-3,9-dihydro-3-pentyl-; 8-chloro-3-pentyl-3,7-dihydro-1H-purine-2,6-dione; 8-Chloro-6-hydroxy-3-pentyl-3,9-dihydro-2H-purin-2-one. Grade: ≥95%. CAS No. 862892-90-8. Molecular formula: C10H13ClN4O2. Mole weight: 256.69. | |
| H-Pro-NH2 | An impurity of Vildagliptin. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: L-Prolinamide; (2S)-2-Pyrrolidinecarboxamide; (-)-Prolinamide; (2S)-2-Carbamoylpyrrolidine; (2S)-Pyrrolidine-2-carboxylic acid amide; (S)-2-(Aminocarbonyl)pyrrolidine; (S)-Prolinamide; (S)-Proline Amide; 2-Pyrrolidinecarboxamide, (2S)-; 2-Pyrrolidinecarboxamide, (S)-; Prolinamide, L-; (S)-Pyrrolidine-2-carboxamide; (S)-Pyrrolidine-2-carboxylic acid amide; L-Proline amide. Grade: ≥95%. CAS No. 7531-52-4. Molecular formula: C5H10N2O. Mole weight: 114.10. | |
| LG 100268 | LG 100268 is a potent RXR agonist for evaluation in the treatment of non-insulin-dependent (type II) diabetes mellitus (NIDDM). Group: Biochemicals. Alternative Names: 6-[1- (5, 6, 7, 8-tetrahydro-3, 5, 5, 8, 8-pentamethyl-2-naphthalenyl) cyclopropyl]-3-Pyridinecarboxylic Acid; AGN 192620; ALRT 268; CD 3127; LG 268; LGD 100268; LGD 1268. Grades: Highly Purified. CAS No. 153559-76-3. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??NO?, Molecular Weight: US Biological Life Sciences. | Worldwide |
| Nα-Boc-L-ornithine | Nα-Boc-L-Ornithine, is a boc-protected analogue of L-Orthinine, a non-essential amino acid and intermediate in arginine biosynthesis. It can be used in the enzymatic preparation of N-BOC-5-hydroxy-L-proline, and N-Cbz-5-hydroxy-L-proline, which are alternative key intermediates for the synthesis of Saxagliptin, used for the treatment of type II diabetes mellitus. Synonyms: Boc-L-Orn-OH; (2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid; Boc-Orn-OH; L-5-Amino-2-tert-butoxycarbonylamino-pentanoicacid; Boc-L-ornithine; Nalpha-Boc-L-ornithine; N2-Boc-L-ornithine. Grade: ≥ 99% (HPLC). CAS No. 21887-64-9. Molecular formula: C10H20N2O4. Mole weight: 232.30. | |
| (+)-O,O'-Dibenzoyl-D-tartaric Acid Monohydrate | (+)-Dibenzoyl-D-Tartaric Acid Monohydrate can be used to treat type 2 diabetes mellitus. Synonyms: (2S,3S)-2,3-dibenzoyloxybutanedioic acid; hydrate; (2S,3S)-2,3-dibenzoyloxybutanedioic acid; hydrate. Grade: > 95 %. CAS No. 80822-15-7. Molecular formula: C18H16O9. Mole weight: 376.31. | |
| Pal-Glu(OSu)-OH | Pal-Glu(OSu)-OH is a side chain of Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used for type 2 diabetes mellitus research. Synonyms: (S)-5-((2,5-dioxopyrrolidin-1-yl)oxy)-5-oxo-2-palmitamidopentanoic acid. CAS No. 294855-91-7. Molecular formula: C25H42N2O7. Mole weight: 482.61. | |
| Perindopril-[13C3] | Perindopril-[13C3] is the labelled analogue of Perindopril, which is a long-acting ACE inhibitor used to treat patients with hypertension, diabetes mellitus type 2, coronary heart disease, chronic heart failure or stable coronary artery disease in form of perindopril arginine on the basis of a large evidence. Synonyms: [13C3]-Perindopril; [2S-[1[R*(R*)],2α,3aβ,7aβ]]-1-[2-[[1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl-13C3]octahydro-1H-indole-2-carboxylic Acid; McN-A 2833-13C3. Grade: > 95%. Molecular formula: C16[13C]3H32N2O5. Mole weight: 371.47. | |
| Perindopril Related Compound 6 | An impurity of Perindopril which is used to treat patients with hypertension, diabetes mellitus type 2, coronary heart disease, chronic heart failure or stable coronary artery disease in form of perindopril arginine on the basis of a large evidence. Synonyms: D-Oic-OH; H-D-Oic-OH; D-Octahydroindole-2-carboxylic acid. Grade: > 95%. CAS No. 108507-42-2. Molecular formula: C9H15NO2. Mole weight: 169.22. | |
| Picamilon | Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid. CAS No. 34562-97-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-107482. | |
| Repaglinide ethyl-[d5] | An isotope labelled Repaglinide. Repaglinide is an antidiabetic drug. Repaglinide is an oral medication used in addition to diet and exercise for blood sugar control in type 2 diabetes mellitus. Synonyms: 2-(Ethoxy-d5)-4-[2-[[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic Acid; AG-EE-623-d5; Novonorm-d5; Prandin-d5. Grade: >98%. CAS No. 1217709-85-7. Molecular formula: C27H31D5N2O4. Mole weight: 457.62. | |
| Repaglinide ethyl ester | An impurity of Repaglinide. Repaglinide is an antidiabetic drug. Repaglinide is an oral medication used in addition to diet and exercise for blood sugar control in type 2 diabetes mellitus. Synonyms: 2-Ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic Acid Ethyl Ester; (S)-Ethyl 2-ethoxy-4-[[[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]amino]carbonyl]methyl]benzoate; Repaglinide Impurity. Grade: > 95%. CAS No. 147770-06-7. Molecular formula: C29H40N2O4. Mole weight: 480.65. | |
| (R)-Sitagliptin Defluoro Impurity 3 | Sitagliptin Defluoro Impurity 3 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4-difluorophenyl)butanoic acid; (3R)-3-[(tert-Butoxycarbonyl)amino]-4-(2,4-difluorophenyl)butanoic acid. Grade: >90%. CAS No. 851307-12-5. Molecular formula: C15H19F2NO4. Mole weight: 315.31. | |
| (R)-Sitagliptin Defluoro Impurity 4 | (R)-Sitagliptin Defluoro Impurity 4 is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin impurity R; (R)-beta-(Boc-amino)-2,5-difluorobenzenebutanoic acid; (R)-3-[((tert-Butoxy)carbonyl)amino]-4-(2,5-difluorophenyl)butanoic acid. CAS No. 486459-98-7. Molecular formula: C15H19F2NO4. Mole weight: 315.31. | |
| S-(2-Carboxyethyl)-L-cysteine | An advanced glycation end product, found in elevated concentrations within Diabetes Mellitus patients. Group: Biochemicals. Alternative Names: L-3-[ (2-Carboxyethyl) thio]alanine; 2-Amino-4-thiaheptanedioic Acid; S-(2-Carboxyethyl)cysteine; CEC: Grades: Highly Purified. CAS No. 100429-59-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| (S)-3-((tert-butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic acid | (S)-3-((tert-butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic acid is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin Impurity 24; Benzenebutanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-2,5-difluoro-, (βS)-. CAS No. 2349567-54-8. Molecular formula: C15H19F2NO4. Mole weight: 315.32. | |
| Saroglitazar | Saroglitazar is a drug for the treatment of type 2 diabetes mellitus and dyslipidemia. It is approved for use in India by the Drug Controller General of India. Saroglitazar has demonstrated reduction of triglycerides (TG), LDL cholesterol, VLDL cholesterol, non-HDL cholesterol and an increase in HDL cholesterol a characteristic hallmark of atherogenic diabetic dyslipidemia (ADD). Saroglitazar is novel first in class drug which acts as a dual PPAR agonist at the subtypes α (alpha) and γ (gamma) of the peroxisome proliferator-activated receptor (PPAR). Agonist action at PPARα lowers high blood triglycerides, and agonist action on PPARγ improves insulin resistance and consequently lowers blood sugar. Group: Biochemicals. Alternative Names: (α S) -α -Ethoxy-4- [2- [2-methyl-5- [4- (methylthio) phenyl] -1H-pyrrol-1-yl] ethoxy] benzenepropanoic Acid; ZYH1; ZYH-1; ZYH 1; Lipaglyn. IUPAC/Chemical Name: (S) -2-ethoxy-3- (4- (2- (2-methyl-5- (4- (methylthio) phenyl) -1H-pyrrol-1-yl) ethoxy) phenyl) propanoic acid. Grades: Highly Purified. CAS No. 495399-09-2. Pack Sizes: 25mg. Molecular Formula: C??H??NO?S, Molecular Weight: 439.57. US Biological Life Sciences. | Worldwide |
| Sitagliptin FP Impurity E Hydrochloride | Sitagliptin EP Impurity E is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin Impurity 17 HCl; Sitagliptin Acid Impurity HCl; (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid Hydrochloride; (βR)-β-Amino-2,4,5-trifluorobenzenebutanoic Acid Hydrochloride. Grade: >95%. CAS No. 1204818-19-8. Molecular formula: C10H11ClF3NO2. Mole weight: 269.65. | |
| Sitagliptin Impurity 19 | Sitagliptin Impurity 19 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-Sitagliptin N-Boc-Acid Impurity; (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid; Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid. Grade: >95%. CAS No. 486460-00-8. Molecular formula: C15H18F3NO4. Mole weight: 333.3. | |
| Sitagliptin Impurity 21 | Sitagliptin Impurity 21 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Boc-D-β-homophenylalanine; Boc-D-β-Homophe-OH; (R)-3-(Boc-amino)-4-phenylbutyric acid; N-β-(t-Butoxycarbonyl)-D-β-homophenylalanine. Grade: >97%. CAS No. 101555-61-7. Molecular formula: C15H21NO4. Mole weight: 279.33. | |
| Sitagliptin Related Compound 1 | Sitagliptin Related Compound 1 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-3-((tert-Butoxycarbonyl)amino)-4-(3-fluorophenyl)butanoic acid; Boc-(R)-3-amino-4-(3-fluorophenyl)-butyric acid. Grade: >95%. CAS No. 331763-66-7. Molecular formula: C15H20FNO4. Mole weight: 297.32. | |
| (S)-Methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate Tartaric acid salt | (S)-Methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate Tartaric acid salt is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Benzenebutanoic acid, β-amino-2,4,5-trifluoro-, methyl ester, (βR)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1); Sitagliptin Impurity 85. CAS No. 1384431-02-0. Molecular formula: C15H18F3NO8. Mole weight: 397.30. | |
| (S)-Sitagliptin N-Boc-Acid Impurity | (S)-Sitagliptin N-Boc-Acid Impurity is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin Impurity 41; Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid; (βS)?-β-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-2,?4,?5-trifluoro-benzenebutanoic Acid; (S)-3-((tert-butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid. Grade: >95%. CAS No. 922178-94-7. Molecular formula: C15H18F3NO4. Mole weight: 333.3. | |
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