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A cell-permeable flavone derivative that arrests the proliferation of acute myeloid leukemia cells (NB4, U937, HL-60, OCI AML3), in a dose and time-dependent manner (optimum at ~20uM and 96h) and blocks the colony formation in samples from acute myeloid leukemia patients, without affecting normal blood cells. Shown to reduce mitochondrial membrane potential and Bad phosphorylation (at Ser136), induce Bax and caspase 3, 8, and 9 activation in U937 cells. Does not affect the phosphorylation of Akt1, but significantly reduces the expression and phosphorylation of p70S6 kinase in U937 cells. Reported to inhibit the chymotrypsin-like activity of proteasome (IC50 = 2.0uM) and this effect is synergistic with bortezomib. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
3-Hydroxy-2'-methoxyflavone
3-Hydroxy-2'-methoxyflavone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: METHOXYFLAVONOL, 2'-;3-HYDROXY-2'-METHOXYFLAVONE;2'-METHOXYFLAVONOL. Product Category: Heterocyclic Organic Compound. CAS No. 29219-03-2. Molecular formula: C16H12O4. Mole weight: 268.26. Product ID: ACM29219032. Alfa Chemistry ISO 9001:2015 Certified.
3-Hydroxy-5-methoxyflavone
3-Hydroxy-5-methoxyflavone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: METHOXYFLAVONOL, 5-;5-METHOXYFLAVONOL;3-HYDROXY-5-METHOXYFLAVONE. Product Category: Heterocyclic Organic Compound. CAS No. 6665-81-2. Molecular formula: C16H12O4. Mole weight: 268.26. Product ID: ACM6665812. Alfa Chemistry ISO 9001:2015 Certified.
3-Hydroxy-6-Methoxyflavone
3-Hydroxy-6-Methoxyflavone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-Hydroxy-6-methoxyflavone;6-Methoxyflavonol. Product Category: Heterocyclic Organic Compound. Appearance: Powder. CAS No. 93176-00-2. Molecular formula: C16H12O4. Mole weight: 268.2. Purity: 0.98. Product ID: ACM93176002. Alfa Chemistry ISO 9001:2015 Certified.
4,5-Dihydroxy-7-methoxyflavone
4,5-Dihydroxy-7-methoxyflavone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5,4-DIHYDROXY-7-METHOXYFLAVONE;4,5-DIHYDROXY-7-METHOXYFLAVONE;7-METHOXYAPIGENIN;GENKWANIN;APIGENIN-7-METHYL ETHER;7-Methylapigenin;7-O-Methylapigenin;Apigenin 7-O-Methyl Ether. Product Category: Heterocyclic Organic Compound. CAS No. 437-64-9. Molecular formula: C16H12O5. Mole weight: 284.26. Density: 1.42. Product ID: ACM437649. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4',5-Dihydroxy-7-methoxyflavone.
4'-Methoxyflavone is a flavonoid with antioxidant properties and anti-proliferative activity against cancer cells. 4'-Methoxyflavone can inhibit cycle-dependent kinases leading to cell cycle arrest and regulate cell signaling pathways to influence cell proliferation and apoptosis. 4'-Methoxyflavone can be used in cancer chemoprevention research [1]. Uses: Scientific research. Group: Natural products. CAS No. 4143-74-2. Pack Sizes: 10 mg; 25 mg. Product ID: HY-139054.
5,8,4'-Trihydroxy-7-methoxyflavone 8-O-glucoside
5,8,4'-Trihydroxy-7-Methoxyflavone 8-O-glucoside is a natural flavonoid found in the herbs of Andrographis paniculata. Synonyms: 8-(beta-D-Glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one. Grade: >98%. CAS No. 710952-13-9. Molecular formula: C22H22O11. Mole weight: 462.41.
5-Methoxyflavone
5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-Methoxyflavone, Oprea1_842256, Oprea1_859852, M8422_SIGMA, ghl.PD_Mitscher_leg0.1155, MEGxp0_001704, ACon1_000175, 5-Methoxy-2-phenyl-4-benzopyrone, EINECS 255-652-0, ZINC00005954, NCGC00142613-01, NCGC00142613-02, NCGC00180810-01, ST069360, 42079-78-7. Product Category: Inhibitors. Appearance: powder. CAS No. 42079-78-7. Molecular formula: C16H12O3. Mole weight: 252.26. Purity: 0.97. IUPACName: 5-methoxy-2-phenylchromen-4-one. Canonical SMILES: COC1=CC=CC2=C1C(=O)C=C(O2)C3=CC=CC=C3. Density: 1.24g/cm³. ECNumber: 255-652-0. Product ID: ACM42079787. Alfa Chemistry ISO 9001:2015 Certified.
5-Methoxyflavone
5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABA A receptors. Uses: Scientific research. Group: Signaling pathways. CAS No. 42079-78-7. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-107790.
5-Methoxyflavone
5-Methoxyflavone. Group: Biochemicals. Alternative Names: 5-Methoxy-2-phenyl chromen-4-one. Grades: Highly Purified. CAS No. 42079-78-7. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C16H12O3. US Biological Life Sciences.
Worldwide
5-Methoxyflavone
5-methoxyflavone is a novel DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. Synonyms: 4H-1-Benzopyran-4-one, 5-methoxy-2-phenyl-; 5-Methoxy-2-phenyl-4H-1-benzopyran-4-one; Flavone, 5-methoxy-. Grade: ≥98%. CAS No. 42079-78-7. Molecular formula: C16H12O3. Mole weight: 252.26.
5-Methoxyflavone 98+% (GC)
5-Methoxyflavone 98+% (GC). Group: Biochemicals. Grades: GC. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
6-Methoxyflavone
6-Methoxyflavone is a methoxyflavone that can be isolated from Pimelea simplex F. Muell. and P. decora Domin. 6-Methoxyflavone exhibits anti-inflammatory effects and neuropathic pain relieving properties in chemotherapy-induced peripheral neuropathy (CIPN). 6-Methoxyflavone can be used in the research of nephritis [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 26964-24-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W097625.
7-Methoxyflavone
7-Methoxyflavone is a compound isolated from Zornia brasiliensis. 7-Methoxyflavone has peripheral antinociceptive activity. 7-Methoxyflavone inhibits paw-licking time in the neurogenic phase of the formalin pain response (65.6%) and did not decrease the nociceptive response in the inflammatory phase [1]. Uses: Scientific research. Group: Natural products. CAS No. 22395-22-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N8487.
7-methoxyflavone 98% HPLC
7-methoxyflavone 98% HPLC.
CA, FL & NJ
Genkwanin (4',5-Dihydroxy-7-methoxyflavone)
Atmosphere: Group: Biochemicals. Alternative Names: 4',5-Dihydroxy-7-methoxyflavone. Grades: Highly Purified. CAS No. 437-64-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
3,5,7-Tri-O-hexanoyldiosmetin
Diosmetin derivative. Group: Biochemicals. Alternative Names: 3',5,7-Tri-O-hexanoyl-4'-methoxyflavone. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
3-methylquercetin 7-O-methyltransferase
Involved with EC 2.1.1.76 quercetin 3-O-methyltransferase and EC 2.1.1.83 3,7-dimethylquercetin 4'-O-methyltransferase in the methylation of quercetin to 3,7,4'-trimethylquercetin in Chrysosplenium americanum. Does not act on flavones, dihydroflavonols, or their glucosides. Group: Enzymes. Synonyms: flavonol 7-O-methyltransferase; flavonol 7-methyltransferase; 7-OMT; S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase; 3-methylquercitin 7-O-methyltransferase [mis-spelt]. Enzyme Commission Number: EC 2.1.1.82. CAS No. 97089-67-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1983; 3-methylquercetin 7-O-methyltransferase; EC 2.1.1.82; 97089-67-3; flavonol 7-O-methyltransferase; flavonol 7-methyltransferase; 7-OMT; S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase; 3-methylquercitin 7-O-methyltransferase [mis-spelt]. Cat No: EXWM-1983.
3-O-Methyl Quercetin
A metabolite of the flavanoid Quercetin with inhibitory activity on lipopolysaccharide-induced activation of macrophage U937 cells. Group: Biochemicals. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-1-benzopyran-4-one; 3-Methoxy-3',4',5,7-tetrahydroxyflavone; 3-Methylquercetin; 3-Methylquercetol; 3',4',5,7-Tetrahydroxy-3-methoxyflavone; 5,7,3',4'-Tetrahydroxy-3-methoxyflavone; NSC 154016; Quercetin 3-Methyl Ether; Quercetin-3-O-methyl Ether. Grades: Highly Purified. CAS No. 1486-70-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
4'-Hydroxywogonin
4'-Hydroxywogonin is a flavonoid isolated from the roots of Scutellaria baicalensis Georgi. Synonyms: 5,7,4'-trihydroxy-8-methoxyflavone. Grade: 98%. CAS No. 57096-02-3. Molecular formula: C16H12O6. Mole weight: 300.3.
4'-O-Methyl quercetin
4'-O-Methyl quercetin. Group: Biochemicals. Alternative Names: 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; 3,3',5,7-Tetrahydroxy-4'-methoxyflavone; Tamaraxetin. Grades: Highly Purified. CAS No. 603-61-2. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H12O7. US Biological Life Sciences.
Worldwide
5-O-Methyl Quercetin
O-Methylated analogue of the flavanoid Quercertin. It is a small molecule inhibitor of NADPH Oxidase 4 enzyme. It is used in studies of flavonoid structure requirement for the increment of ocular blood flow in the rabbit and retinal function recovery in rat eyes. Group: Biochemicals. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-5-methoxy-4H-1-benzopyran-4-one; 3,3',4,7-Tetrahydroxy-5-methoxyflavone; Azaleatin; Quercetin 5-Methyl Ether. Grades: Highly Purified. CAS No. 529-51-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
7-O-Methyl Quercetin
O-Methylated metabolite of the flavanoid Quercertin with antioxidant activity. Group: Biochemicals. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-y-methoxy-4H-1-benzopyran-4-one; Rhamnetin; 3,3',4',5-Tetrahydroxy-7-methoxyflavone; 7-Methoxyquercetin; 3,5,3',4'-Tetrahydroxy-7-methoxyflavone; 7-Methylquercetin; C.I. 75690; LY 805921; NSC 19802; Quercetin 7-Methyl Ether; β-Rhamnocitrin. Grades: Highly Purified. CAS No. 90-19-7. Pack Sizes: 5mg. US Biological Life Sciences.
Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an orally active flavonoid derived from Dendranthema morifolium. Acacetin docks in the ATP binding pocket of PI3K&gamma. Acacetin causes cell cycle arrest and induces apoptosis and autophagy in cancer cells. Acacetin has potent anti-cancer and anti-inflammatory activity and has the potential for pain-related diseases research [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 5,7-Dihydroxy-4'-methoxyflavone. CAS No. 480-44-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0451.
Acacetin
VEGF expression inhibitor and tumor angiogenesis. A flavonoid with antiaggregatory activity in human blood. Group: Biochemicals. Alternative Names: 2-(4-Methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one; 4'-O-Methylapigenin; 5,7-Dihydroxy-4'-methoxyflavone; LY 064233; Linarigenin; NSC 76061. Grades: Highly Purified. CAS No. 480-44-4. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Chrysoeriol
A methoxyflavonoid that selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells. A metabolite of Luteolin. Group: Biochemicals. Alternative Names: 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; 4',5,7-Trihydroxy-3'-methoxyflavone; 3'-Methoxy-4',5,7-trihydroxyflavone; 3'-Methoxyapigenin; 3'-O-Methylluteolin; 5,7,4'-Trihydroxy-3'-methoxyflavone; Chrysoriol; Luteolin 3'-Methyl Ether. Grades: Highly Purified. CAS No. 491-71-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??O?, Molecular Weight: 300.26. US Biological Life Sciences.
Worldwide
Chrysoeriol
Chrysoeriol is a natural compound isolated from the herbs of Medicago sativa. Chrysoeriol can potently inhibit the induction of nitric oxide synthase by blocking activator protein 1 (AP-1) activation and its anti-inflammatory effects. Chrysoeriol can induce nod genes in rhizobium meliloti. Chrysoeriol can inhibit the downstream signal transduction pathways of platelet-derived growth factor (PDGF)-Rbeta, including ERK1/2, p38, and Akt phosphorylation, which suggests that chrysoeriol may be used for the prevention and treatment of vascular diseases during restenosis after coronary angioplasty. Synonyms: 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; 4',5,7-Trihydroxy-3'-methoxyflavone; 3'-Methoxy-4',5,7-trihydroxyflavone; 3'-Methoxyapigenin; 3'-O-Methylluteolin; 5,7,4'-Trihydroxy-3'-methoxyflavone; Chrysoriol; Luteolin 3'-Methyl Ether; Scoparol; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-. Grade: 98.0%. CAS No. 491-71-4. Molecular formula: C16H12O6. Mole weight: 300.27.
DD1
DD1 is a proteasome inhibitor that targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis. Synonyms: 3,3'-Diamino-4'-methoxyflavone; 4H-1-Benzopyran-4-one, 3-amino-2-(3-amino-4-methoxyphenyl)-. Grade: >98%. CAS No. 187585-11-1. Molecular formula: C16H14N2O3. Mole weight: 282.29.
Diethyl-[(3-ethyl-7-methoxy-4-oxo-2-phenylchromen-8-yl)methyl]azaniumchloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CID49669, LS-68962, 8-(Diethylaminomethyl)-3-ethyl-7-methoxyflavone hydrochloride, FLAVONE, 8-(DIETHYLAMINOMETHYL)-3-ETHYL-7-METHOXY-, HYDROCHLORIDE, 67238-70-4. Product Category: Heterocyclic Organic Compound. CAS No. 67238-70-4. Molecular formula: C23H28ClNO3. Mole weight: 401.926 g/mol. Purity: 0.96. IUPACName: diethyl-[(3-ethyl-7-methoxy-4-oxo-2-phenylchromen-8-yl)methyl]azanium chloride. Canonical SMILES: CCC1=C(OC2=C(C1=O)C=CC(=C2C[NH+](CC)CC)OC)C3=CC=CC=C3.[Cl-]. Product ID: ACM67238704. Alfa Chemistry ISO 9001:2015 Certified. Categories: DTXSID60986371.
Diosmetin
analytical standard. Group: Chemical classimpurity standards. Alternative Names: Flavone, 3',5,7-trihydroxy-4'-methoxy- (7CI,8CI), Disomin Imp. F (EP), Diosmetol, Luteolin 4'-methyl ether, 3',5,7-Trihydroxy-4'-methoxyflavone, Diosmetine,4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, Diosmetin (6CI), Pillon, 4'-Methylluteolin, 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one, 5,7,3'-Trihydroxy-4'-methoxyflavone.
Diosmetin
Diosmetin - Product ID: NST-10-70. Category: Flavonoids. Alternative Names: 3',5,7-Trihydroxy-4'-methoxyflavone. Purity: 98%. Test method: HPLC. CAS No. 520-34-3. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: Light yellow powder. Molecular formula: C16H12O6. Mole weight: 300.26. Storage: +2 +8 °C.
Diosmetine Triacetate
Diosmetin derivative. A polyphenol found in Honeybush Tea. Group: Biochemicals. Alternative Names: 5,7-Bis(acetyloxy)-2-[3-(acetyloxy)-4-methoxyphenyl]-4H-1-benzopyran-4-one; 3',5,7-Trihydroxy-4'-methoxy-flavone Triacetate; 3',5,7-Triacetoxy-4'-methoxyflavone; Diosmetin Triacetate. Grades: Highly Purified. CAS No. 3162-5-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Diosmetine Tri-O-benzoyl
Diosmetin derivative. Group: Biochemicals. Alternative Names: 3',5,7-Tri-O-benzoyl-4'-methoxy-flavone; 3',5,7-Tri-O-benzoyl-4'-methoxyflavone; Diosmetin Tri-O-benzoyl. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Diosmin is a flavonoid glycoside found in citrus fruits. Diosmin exhibits vasoprotective, anti-inflammatory, free-radical scavenging, and antimutagenic properties via inhibiting prostaglandin E2 and thromboxane A2. It also inhibits the adhesion, migration, and activation of leukocytes at the capillary level. Diosmin can be used in health products. Uses: Vascular protectant. Synonyms: 7-[6-O-Deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl)oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; 3',5,7-Trihydroxy-4'-methoxyflavone 7-rutinoside; Diosmetin 7-b-rutinoside. Grade: ≥ 98%. CAS No. 520-27-4. Molecular formula: C28H32O15. Mole weight: 608.54.
Genkwanin. Group: Biochemicals. Alternative Names: 4',5-Dihydroxy-7-methoxyflavone; 7-Methylapigenin; 7-O-Methylapigenin. Grades: Highly Purified. CAS No. 437-64-9. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C16H12O5. US Biological Life Sciences.
Worldwide
Isorhamnetin 3-O-glucoside
Isorhamnetin-3-O-beta-D-Glucoside is a glycosyloxyflavone found in many vegetables. Uses: For the prevention and/or treatment of diabetes and its complications. Synonyms: 3-(β-D-Glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; Flavone, 3,4',5,7-tetrahydroxy-3'-methoxy-, 3-β-D-glucopyranoside; Isorhamnetin 3-glucoside; 3,4',5,7-Tetrahydroxy-3'-methoxyflavone 3-β-D-glucopyranoside; 3,5,7,4'-Tetrahydroxy-3'-methoxyflavone 3-β-D-glucoside; 3'-O-Methylquercetin 3-glucoside; 5,7,4'-Trihydroxy-3'-methoxyflavone 3-O-β-glucopyranoside; Isorhamnetin 3-D-glucoside; Isorhamnetin 3-O-β-D-glucopyranoside; Isorhamnetin 3-O-β-D-glucoside; Isorhamnetin 3-O-β-glucoside; Isorhamnetin 3-β-D-glucopyranoside; Isorhamnetin 3-β-D-glucoside. Grade: 97%. CAS No. 5041-82-7. Molecular formula: C22H22O12. Mole weight: 478.40.
Kaempferide
Kaempferide is a flavonoid that maintains anti-radical and anti-oxidant capabilities, as well as anti-tumor possibilities. Impurity of Icaritin (I163700). Group: Biochemicals. Alternative Names: 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one, 3,5,7-trihydroxy-4'-methoxy-flavone; 3,5,7-Trihydroxy-4'-methoxyflavone; 4'-Methoxykaempferol; 4'-Methylkaempferol; 4'-O-Methylkaempferol; 5,7-Dihydroxy-4'-methoxyflavonol; Kaempferid; Kaempferol 4'-O-methyl ether; Kaempferol 4'-methyl ether; Kaempherol 4'-O-methyl ether; NSC 407294. Grades: Highly Purified. CAS No. 491-54-3. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Nepetin
Nepetin. Group: Biochemicals. Alternative Names: Nepetin; 6-Methoxyluteolin; 3',4',5,7-Tetrahydroxy-6-methoxyflavone. Grades: Plant Grade. CAS No. 520-11-6. Pack Sizes: 10mg. Molecular Formula: C16H12O7, Molecular Weight: 316.262. US Biological Life Sciences.
Worldwide
Oroxylin A
Oroxylin A is a natural flavonoid found in the seeds of Oraxylum indicum (L.) Kurz. Oroxylin A exhibits anti-inflammation activity, it can inhibit LPS-induced iNOS and COX-2 gene expression by blocking NF-κB activation. Uses: Anticancer,antibacterial;anti-tumor. Synonyms: 5,7-dihydroxy-6-methoxyflavone; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one; 6-Methoxybaicalein; baicalein 6-methyl ether. Grade: 98%. CAS No. 480-11-5. Molecular formula: C16H12O5. Mole weight: 284.26.
Spinosin
Spinosin ameliorated memory impairment induced through AβO, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. Therefore, Spinosin might be a useful agent against the amyloid b protein-induced cognitive dysfunction observed in AD patients. Uses: Anxiolytic. Synonyms: spinosin; 2-(4-Hydroxyphenyl)-5-hydroxy-7-methoxy-6-[2-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl]-4H-1-benzopyran-4-one; 2''-O-β-D-Glucopyranosylswertisin; 6-(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)-4',5-dihydroxy-7-methoxyflavone; 6-(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one; Spinosin A; 6-(2-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one; FlavoayaMenin. Grade: >98%. CAS No. 72063-39-9. Molecular formula: C28H32O15. Mole weight: 608.55.
Tamarixetin
Tamarixetin is a natural flavonoid isolated from the herbs of Heracleum stenopterum with anticancer and antiplasmodial activity. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways. Uses: Anticancer. Synonyms: 4'-Methoxyquercetin; 4'-O-Methyl Quercetin; 4'-O-Methylquercetin; Quercetin 4'-methyl ether; 3,3',5,7-Tetrahydroxy-4'-methoxyflavonel; 3-O-rhamnopyranosyl-1-2-glucopyranoside. Grade: 98%. CAS No. 603-61-2. Molecular formula: C16H12O7. Mole weight: 316.26.
Tectochrysin
Tectochrysin is a flavonoid isolated from the heartwood of Pinus strobus L. It leads to apoptotic cell death in NSCLC cells through activating of DR3 and Fas expression. Uses: Antioxidant. Synonyms: 5-hydroxy-7-methoxyflavone; 5-Hydroxy-7-methoxy-2-phenyl-4H-chromen-4-one. Grade: 99%. CAS No. 520-28-5. Molecular formula: C16H12O4. Mole weight: 268.3.
Wogonin
Anti-inflammatory. Increases nitroc oxide (NO) production. Inhibits PGE2, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOS II). Antioxidant. Anti-viral. Shows anti-hepatitis B virus activity. MCP-1 inhibitor. Shows anxiolytic effect through modulation of the GABA(A) receptor complex. Antifungal. Neuroprotective. Anticancer compound. Apoptosis and cell cycle arrest inducer. Sensitizes TNFalpha- and TRAIL-induced apoptosis. Antiangiogenic. NF-kappaB inhibitor. Telomerase activity inhibitor. CDK9 inhibitor. PI3K-AKT pathway modulator. Autophagy inducer. Group: Biochemicals. Alternative Names: WOG, 5,7-Dihydroxy-8-methoxyflavone, BRN 0287152. Grades: Highly Purified. CAS No. 632-85-9. Pack Sizes: 5mg, 25mg. Molecular Formula: C16H12O5. US Biological Life Sciences.
Worldwide
Wogonin
Wogonin is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties. Uses: Antibacterial; antimicrobial; antioxidant; diuretic; anti-inflammatory; anti-tumor. Synonyms: 5,7-dihydroxy-8-methoxy-2-phenyl-4h-1-benzopyran-4-on; 5,7-dihydroxy-8-methoxyflavone. Grade: >98%. CAS No. 632-85-9. Molecular formula: C16H12O5. Mole weight: 284.26.
1-?[2-?Hydroxy-?4, ?6-?bis[ (2-?methoxyethoxy) ?methoxy]?phenyl]?-?3-?[3-?methoxy-?4-?[ (2-?methoxyethoxy) ?methoxy]?phenyl]?-2-?propen-?1-?one is an intermediate in synthesizing Chrysoeriol (C432820), a methoxyflavonoid that selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells. A metabolite of Luteolin (L475000). Group: Biochemicals. Grades: Highly Purified. CAS No. 1456788-16-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C28H38O12, Molecular Weight: 566.59. US Biological Life Sciences.
1- [2-Hydroxy-4, 6-bis [ (2-methoxyethoxy) methoxy] phenyl] ethanone is an intermediate in synthesizing Chrysoeriol (C432820), a methoxyflavonoid that selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells. A metabolite of Luteolin (L475000). Group: Biochemicals. Grades: Highly Purified. CAS No. 260547-80-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H24O8, Molecular Weight: 344.36. US Biological Life Sciences.
Worldwide
3'-Methoxyflavonol
3'-Methoxyflavonol is a selective agonist of neuromedin U 2 receptor ( NMU2R ). Uses: Scientific research. Group: Natural products. CAS No. 76666-32-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N6629.
4'-Methoxyflavonol
4'-Methoxyflavonol is a synthesized flavone/flavonol with 1, 2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayers [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6889-78-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-111803.
6-Methoxyflavonol
6-Methoxyflavonol (Compound 15) is a natural flavone isolated from the marine-derived fungus Aspergillus candidus [1]. Uses: Scientific research. Group: Natural products. CAS No. 93176-00-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N8571.
Hesperetin 7-O-β-D-glucopyranoside
Hesperetin 7-O-β-D-glucopyranoside is a flavonoid glycoside derived from the enzyme-catalyzed transformation of hesperidin. It serves as a potent inhibitor of human HMG-CoA reductase, which plays a role in cholesterol synthesis, and also exhibits blood pressure-lowering effects. Additionally, it has been shown to effectively inhibit the growth of Helicobacter pylori, a bacterium associated with peptic ulcers and gastritis. It has a wide range of biological activities, including antioxidant, anti-inflammatory, antimicrobial, anti-carcinogenic, cardio-protective, and antidepressant effects. Synonyms: 7-(β-D-Glucopyranosyloxy)-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; Flavanone, 3',5,7-trihydroxy-4'-methoxy-, 7-β-D-glucoside; 5,3'-Dihydroxy-4'-methoxyflavonone-7-O-glucoside; hesperitin-7-O-beta-D-glucoside; 7-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone. Grade: ≥98%. CAS No. 906320-94-3. Molecular formula: C22H24O11. Mole weight: 464.42.
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