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A cell-permeable flavone derivative that arrests the proliferation of acute myeloid leukemia cells (NB4, U937, HL-60, OCI AML3), in a dose and time-dependent manner (optimum at ~20uM and 96h) and blocks the colony formation in samples from acute myeloid leukemia patients, without affecting normal blood cells. Shown to reduce mitochondrial membrane potential and Bad phosphorylation (at Ser136), induce Bax and caspase 3, 8, and 9 activation in U937 cells. Does not affect the phosphorylation of Akt1, but significantly reduces the expression and phosphorylation of p70S6 kinase in U937 cells. Reported to inhibit the chymotrypsin-like activity of proteasome (IC50 = 2.0uM) and this effect is synergistic with bortezomib. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
3-Hydroxy-2'-methoxyflavone
3-Hydroxy-2'-methoxyflavone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: METHOXYFLAVONOL, 2'-;3-HYDROXY-2'-METHOXYFLAVONE;2'-METHOXYFLAVONOL. Product Category: Heterocyclic Organic Compound. CAS No. 29219-03-2. Molecular formula: C16H12O4. Mole weight: 268.26. Product ID: ACM29219032. Alfa Chemistry ISO 9001:2015 Certified.
3-Hydroxy-5-methoxyflavone
3-Hydroxy-5-methoxyflavone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: METHOXYFLAVONOL, 5-;5-METHOXYFLAVONOL;3-HYDROXY-5-METHOXYFLAVONE. Product Category: Heterocyclic Organic Compound. CAS No. 6665-81-2. Molecular formula: C16H12O4. Mole weight: 268.26. Product ID: ACM6665812. Alfa Chemistry ISO 9001:2015 Certified.
3-Hydroxy-6-Methoxyflavone
3-Hydroxy-6-Methoxyflavone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-Hydroxy-6-methoxyflavone;6-Methoxyflavonol. Product Category: Heterocyclic Organic Compound. Appearance: Powder. CAS No. 93176-00-2. Molecular formula: C16H12O4. Mole weight: 268.2. Purity: 0.98. Product ID: ACM93176002. Alfa Chemistry ISO 9001:2015 Certified.
4,5-Dihydroxy-7-methoxyflavone
4,5-Dihydroxy-7-methoxyflavone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5,4-DIHYDROXY-7-METHOXYFLAVONE;4,5-DIHYDROXY-7-METHOXYFLAVONE;7-METHOXYAPIGENIN;GENKWANIN;APIGENIN-7-METHYL ETHER;7-Methylapigenin;7-O-Methylapigenin;Apigenin 7-O-Methyl Ether. Product Category: Heterocyclic Organic Compound. CAS No. 437-64-9. Molecular formula: C16H12O5. Mole weight: 284.26. Density: 1.42. Product ID: ACM437649. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4',5-Dihydroxy-7-methoxyflavone.
4'-Methoxyflavone
4'-Methoxyflavone is a flavonoid with antioxidant properties and anti-proliferative activity against cancer cells. 4'-Methoxyflavone can inhibit cycle-dependent kinases leading to cell cycle arrest and regulate cell signaling pathways to influence cell proliferation and apoptosis. 4'-Methoxyflavone can be used in cancer chemoprevention research [1]. Uses: Scientific research. Group: Natural products. CAS No. 4143-74-2. Pack Sizes: 10 mg; 25 mg. Product ID: HY-139054.
5-methoxyflavone
5-methoxyflavone is a novel DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. Synonyms: 4H-1-Benzopyran-4-one, 5-methoxy-2-phenyl-; 5-Methoxy-2-phenyl-4H-1-benzopyran-4-one; Flavone, 5-methoxy-. Grades: ≥98%. CAS No. 42079-78-7. Molecular formula: C16H12O3. Mole weight: 252.26.
5-Methoxyflavone
5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-Methoxyflavone, Oprea1_842256, Oprea1_859852, M8422_SIGMA, ghl.PD_Mitscher_leg0.1155, MEGxp0_001704, ACon1_000175, 5-Methoxy-2-phenyl-4-benzopyrone, EINECS 255-652-0, ZINC00005954, NCGC00142613-01, NCGC00142613-02, NCGC00180810-01, ST069360, 42079-78-7. Product Category: Inhibitors. Appearance: powder. CAS No. 42079-78-7. Molecular formula: C16H12O3. Mole weight: 252.26. Purity: 0.97. IUPACName: 5-methoxy-2-phenylchromen-4-one. Canonical SMILES: COC1=CC=CC2=C1C(=O)C=C(O2)C3=CC=CC=C3. Density: 1.24g/cm³. ECNumber: 255-652-0. Product ID: ACM42079787. Alfa Chemistry ISO 9001:2015 Certified.
5-Methoxyflavone
5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABA A receptors. Uses: Scientific research. Group: Signaling pathways. CAS No. 42079-78-7. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-107790.
5-Methoxyflavone
5-Methoxyflavone. Group: Biochemicals. Alternative Names: 5-Methoxy-2-phenyl chromen-4-one. Grades: Highly Purified. CAS No. 42079-78-7. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C16H12O3. US Biological Life Sciences.
Worldwide
5-Methoxyflavone 98+% (GC)
5-Methoxyflavone 98+% (GC). Group: Biochemicals. Grades: GC. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
6-Methoxyflavone
6-Methoxyflavone is a methoxyflavone that can be isolated from Pimelea simplex F. Muell. and P. decora Domin. 6-Methoxyflavone exhibits anti-inflammatory effects and neuropathic pain relieving properties in chemotherapy-induced peripheral neuropathy (CIPN). 6-Methoxyflavone can be used in the research of nephritis [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 26964-24-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W097625.
7-Methoxyflavone
7-Methoxyflavone is a compound isolated from Zornia brasiliensis. 7-Methoxyflavone has peripheral antinociceptive activity. 7-Methoxyflavone inhibits paw-licking time in the neurogenic phase of the formalin pain response (65.6%) and did not decrease the nociceptive response in the inflammatory phase [1]. Uses: Scientific research. Group: Natural products. CAS No. 22395-22-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N8487.
7-methoxyflavone 98% HPLC
7-methoxyflavone 98% HPLC.
CA, FL & NJ
Genkwanin (4',5-Dihydroxy-7-methoxyflavone)
Atmosphere: Group: Biochemicals. Alternative Names: 4',5-Dihydroxy-7-methoxyflavone. Grades: Highly Purified. CAS No. 437-64-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
3,5,7-Tri-O-hexanoyldiosmetin
Diosmetin derivative. Group: Biochemicals. Alternative Names: 3',5,7-Tri-O-hexanoyl-4'-methoxyflavone. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
3-methylquercetin 7-O-methyltransferase
Involved with EC 2.1.1.76 quercetin 3-O-methyltransferase and EC 2.1.1.83 3,7-dimethylquercetin 4'-O-methyltransferase in the methylation of quercetin to 3,7,4'-trimethylquercetin in Chrysosplenium americanum. Does not act on flavones, dihydroflavonols, or their glucosides. Group: Enzymes. Synonyms: flavonol 7-O-methyltransferase; flavonol 7-methyltransferase; 7-OMT; S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase; 3-methylquercitin 7-O-methyltransferase [mis-spelt]. Enzyme Commission Number: EC 2.1.1.82. CAS No. 97089-67-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1983; 3-methylquercetin 7-O-methyltransferase; EC 2.1.1.82; 97089-67-3; flavonol 7-O-methyltransferase; flavonol 7-methyltransferase; 7-OMT; S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase; 3-methylquercitin 7-O-methyltransferase [mis-spelt]. Cat No: EXWM-1983.
3-O-Methyl Quercetin
A metabolite of the flavanoid Quercetin with inhibitory activity on lipopolysaccharide-induced activation of macrophage U937 cells. Group: Biochemicals. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-1-benzopyran-4-one; 3-Methoxy-3',4',5,7-tetrahydroxyflavone; 3-Methylquercetin; 3-Methylquercetol; 3',4',5,7-Tetrahydroxy-3-methoxyflavone; 5,7,3',4'-Tetrahydroxy-3-methoxyflavone; NSC 154016; Quercetin 3-Methyl Ether; Quercetin-3-O-methyl Ether. Grades: Highly Purified. CAS No. 1486-70-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
4'-O-Methyl quercetin
4'-O-Methyl quercetin. Group: Biochemicals. Alternative Names: 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; 3,3',5,7-Tetrahydroxy-4'-methoxyflavone; Tamaraxetin. Grades: Highly Purified. CAS No. 603-61-2. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H12O7. US Biological Life Sciences.
Worldwide
5-O-Methyl Quercetin
O-Methylated analogue of the flavanoid Quercertin. It is a small molecule inhibitor of NADPH Oxidase 4 enzyme. It is used in studies of flavonoid structure requirement for the increment of ocular blood flow in the rabbit and retinal function recovery in rat eyes. Group: Biochemicals. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-5-methoxy-4H-1-benzopyran-4-one; 3,3',4,7-Tetrahydroxy-5-methoxyflavone; Azaleatin; Quercetin 5-Methyl Ether. Grades: Highly Purified. CAS No. 529-51-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
7-O-Methyl Quercetin
O-Methylated metabolite of the flavanoid Quercertin with antioxidant activity. Group: Biochemicals. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-y-methoxy-4H-1-benzopyran-4-one; Rhamnetin; 3,3',4',5-Tetrahydroxy-7-methoxyflavone; 7-Methoxyquercetin; 3,5,3',4'-Tetrahydroxy-7-methoxyflavone; 7-Methylquercetin; C.I. 75690; LY 805921; NSC 19802; Quercetin 7-Methyl Ether; β-Rhamnocitrin. Grades: Highly Purified. CAS No. 90-19-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Acacetin
Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an orally active flavonoid derived from Dendranthema morifolium. Acacetin docks in the ATP binding pocket of PI3K&gamma. Acacetin causes cell cycle arrest and induces apoptosis and autophagy in cancer cells. Acacetin has potent anti-cancer and anti-inflammatory activity and has the potential for pain-related diseases research [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 5,7-Dihydroxy-4'-methoxyflavone. CAS No. 480-44-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0451.
Acacetin
Acacetin isolated from the bark of Acacia farnesiana. It can inhibit p38 and JNK phosphorylation and reduces MMP-1, MMP-3 and MMP-13 expression in interleukin-1β-induced FLSs. Uses: Anti-inflammatory; anti-plasmodial activity; anti-peroxidant activity; anti-cancer and antitumor activities. Synonyms: 5,7-dihydroxy-4'-methoxyflavone. Grades: 0.985. CAS No. 480-44-4. Molecular formula: C16H12O5. Mole weight: 284.3.
Acacetin
VEGF expression inhibitor and tumor angiogenesis. A flavonoid with antiaggregatory activity in human blood. Group: Biochemicals. Alternative Names: 2-(4-Methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one; 4'-O-Methylapigenin; 5,7-Dihydroxy-4'-methoxyflavone; LY 064233; Linarigenin; NSC 76061. Grades: Highly Purified. CAS No. 480-44-4. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Chrysoeriol
A methoxyflavonoid that selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells. A metabolite of Luteolin. Group: Biochemicals. Alternative Names: 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; 4',5,7-Trihydroxy-3'-methoxyflavone; 3'-Methoxy-4',5,7-trihydroxyflavone; 3'-Methoxyapigenin; 3'-O-Methylluteolin; 5,7,4'-Trihydroxy-3'-methoxyflavone; Chrysoriol; Luteolin 3'-Methyl Ether. Grades: Highly Purified. CAS No. 491-71-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??O?, Molecular Weight: 300.26. US Biological Life Sciences.
Diethyl-[(3-ethyl-7-methoxy-4-oxo-2-phenylchromen-8-yl)methyl]azaniumchloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CID49669, LS-68962, 8-(Diethylaminomethyl)-3-ethyl-7-methoxyflavone hydrochloride, FLAVONE, 8-(DIETHYLAMINOMETHYL)-3-ETHYL-7-METHOXY-, HYDROCHLORIDE, 67238-70-4. Product Category: Heterocyclic Organic Compound. CAS No. 67238-70-4. Molecular formula: C23H28ClNO3. Mole weight: 401.926 g/mol. Purity: 0.96. IUPACName: diethyl-[(3-ethyl-7-methoxy-4-oxo-2-phenylchromen-8-yl)methyl]azanium chloride. Canonical SMILES: CCC1=C(OC2=C(C1=O)C=CC(=C2C[NH+](CC)CC)OC)C3=CC=CC=C3.[Cl-]. Product ID: ACM67238704. Alfa Chemistry ISO 9001:2015 Certified. Categories: DTXSID60986371.
Diosmetin
Diosmetin - Product ID: NST-10-70. Category: Flavonoids. Alternative Names: 3',5,7-Trihydroxy-4'-methoxyflavone. Purity: 98%. Test method: HPLC. CAS No. 520-34-3. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: Light yellow powder. Molecular formula: C16H12O6. Mole weight: 300.26. Storage: +2 +8 °C.
Diosmetine Triacetate
Diosmetin derivative. A polyphenol found in Honeybush Tea. Group: Biochemicals. Alternative Names: 5,7-Bis(acetyloxy)-2-[3-(acetyloxy)-4-methoxyphenyl]-4H-1-benzopyran-4-one; 3',5,7-Trihydroxy-4'-methoxy-flavone Triacetate; 3',5,7-Triacetoxy-4'-methoxyflavone; Diosmetin Triacetate. Grades: Highly Purified. CAS No. 3162-5-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Diosmetine Tri-O-benzoyl
Diosmetin derivative. Group: Biochemicals. Alternative Names: 3',5,7-Tri-O-benzoyl-4'-methoxy-flavone; 3',5,7-Tri-O-benzoyl-4'-methoxyflavone; Diosmetin Tri-O-benzoyl. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Genkwanin
Genkwanin. Group: Biochemicals. Alternative Names: 4',5-Dihydroxy-7-methoxyflavone; 7-Methylapigenin; 7-O-Methylapigenin. Grades: Highly Purified. CAS No. 437-64-9. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C16H12O5. US Biological Life Sciences.
Worldwide
Kaempferide
Kaempferide is a flavonoid that maintains anti-radical and anti-oxidant capabilities, as well as anti-tumor possibilities. Impurity of Icaritin (I163700). Group: Biochemicals. Alternative Names: 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one, 3,5,7-trihydroxy-4'-methoxy-flavone; 3,5,7-Trihydroxy-4'-methoxyflavone; 4'-Methoxykaempferol; 4'-Methylkaempferol; 4'-O-Methylkaempferol; 5,7-Dihydroxy-4'-methoxyflavonol; Kaempferid; Kaempferol 4'-O-methyl ether; Kaempferol 4'-methyl ether; Kaempherol 4'-O-methyl ether; NSC 407294. Grades: Highly Purified. CAS No. 491-54-3. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Kaempferide
Kaempferide is an O-methylated flavonol. It can be found in Kaempferia galanga (aromatic ginger). The enzyme kaempferol 4'-O-methyltransferase uses S-adenosyl-L-methionine and kaempferol to produce S-adenosyl-L-homocysteine and kaempferide. Uses: Antioxidant. Synonyms: 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-methoxyphenyl)-; 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; Flavone, 3,5,7-trihydroxy-4'-methoxy-; 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one; 3,5,7-Trihydroxy-4'-methoxyflavone; 4'-Methoxykaempferol; 4'-Methylkaempferol; 4'-O-Methylkaempferol; 4'-O-Methylkaempherol; 5,7-Dihydroxy-4'-methoxyflavonol; Kaempferid; Kaempferol 4'-methyl ether; Kaempferol 4'-O-methyl ether; Kaempherol 4'-O-methyl ether; NSC 407294. Grades: >98%. CAS No. 491-54-3. Molecular formula: C16H12O6. Mole weight: 300.26.
Negletein
Negletein is a flavonoid with anti-inflammatory and immunomodulatory activities. Synonyms: 5,6-Dihydroxy-7-methoxyflavone; Baicalein-7-methylether; 7-O-Methylbaicalein. Grades: >98%. CAS No. 29550-13-8. Molecular formula: C16H12O5. Mole weight: 284.26.
Nepetin
Nepetin. Group: Biochemicals. Alternative Names: Nepetin; 6-Methoxyluteolin; 3',4',5,7-Tetrahydroxy-6-methoxyflavone. Grades: Plant Grade. CAS No. 520-11-6. Pack Sizes: 10mg. Molecular Formula: C16H12O7, Molecular Weight: 316.262. US Biological Life Sciences.
Worldwide
Wogonin
Anti-inflammatory. Increases nitroc oxide (NO) production. Inhibits PGE2, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOS II). Antioxidant. Anti-viral. Shows anti-hepatitis B virus activity. MCP-1 inhibitor. Shows anxiolytic effect through modulation of the GABA(A) receptor complex. Antifungal. Neuroprotective. Anticancer compound. Apoptosis and cell cycle arrest inducer. Sensitizes TNFalpha- and TRAIL-induced apoptosis. Antiangiogenic. NF-kappaB inhibitor. Telomerase activity inhibitor. CDK9 inhibitor. PI3K-AKT pathway modulator. Autophagy inducer. Group: Biochemicals. Alternative Names: WOG, 5,7-Dihydroxy-8-methoxyflavone, BRN 0287152. Grades: Highly Purified. CAS No. 632-85-9. Pack Sizes: 5mg, 25mg. Molecular Formula: C16H12O5. US Biological Life Sciences.
1-?[2-?Hydroxy-?4, ?6-?bis[ (2-?methoxyethoxy) ?methoxy]?phenyl]?-?3-?[3-?methoxy-?4-?[ (2-?methoxyethoxy) ?methoxy]?phenyl]?-2-?propen-?1-?one is an intermediate in synthesizing Chrysoeriol (C432820), a methoxyflavonoid that selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells. A metabolite of Luteolin (L475000). Group: Biochemicals. Grades: Highly Purified. CAS No. 1456788-16-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C28H38O12, Molecular Weight: 566.59. US Biological Life Sciences.
1- [2-Hydroxy-4, 6-bis [ (2-methoxyethoxy) methoxy] phenyl] ethanone is an intermediate in synthesizing Chrysoeriol (C432820), a methoxyflavonoid that selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells. A metabolite of Luteolin (L475000). Group: Biochemicals. Grades: Highly Purified. CAS No. 260547-80-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H24O8, Molecular Weight: 344.36. US Biological Life Sciences.
Worldwide
3'-Methoxyflavonol
3'-Methoxyflavonol is a selective agonist of neuromedin U 2 receptor ( NMU2R ). Uses: Scientific research. Group: Natural products. CAS No. 76666-32-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N6629.
4'-Methoxyflavonol
4'-Methoxyflavonol is a synthesized flavone/flavonol with 1, 2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayers [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6889-78-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-111803.
6-Methoxyflavonol
6-Methoxyflavonol (Compound 15) is a natural flavone isolated from the marine-derived fungus Aspergillus candidus [1]. Uses: Scientific research. Group: Natural products. CAS No. 93176-00-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N8571.
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