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Ethyl Isobutyrylacetate-d6 (Ethyl 4-Methyl-3-oxopentanoate-d6). Group: Biochemicals. Alternative Names: Ethyl 4-Methyl-3-oxopentanoate-d6. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
methyl 2-fluoro-3-oxopentanoate
One of the impurities of Voriconazole, which has been found to be an ergosterol biosynthesis inhibitor and could be used as an antifungal agent. Synonyms: pentanoic acid, 2-fluoro-3-oxo-, methyl ester; Voriconazole Impurity 23. CAS No. 180287-02-9. Molecular formula: C6H9FO3. Mole weight: 148.13.
Methyl 2-methyl-3-oxopentanoate
Methyl 2-methyl-3-oxopentanoate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Methyl 2-methyl-3-oxopentanoate, Pentanoic acid, 2-methyl-3-oxo-, methyl ester, 17422-12-7, AC1LC0V3, CTK0E4171, MolPort-001-811-915, AKOS010952273, MCULE-2153331264, 2-Methyl-3-oxo-pentanoicacid methyl ester, 2-methyl-3-oxo-pentanoic acid methyl ester, X2072, EN300-80573. Product Category: Heterocyclic Organic Compound. CAS No. 17422-12-7. Molecular formula: C7H12O3. Mole weight: 144.1684. Purity: 0.96. IUPACName: methyl 2-methyl-3-oxopentanoate. Canonical SMILES: CCC(=O)C(C)C(=O)OC. Density: 0.993g/cm³. Product ID: ACM17422127. Alfa Chemistry ISO 9001:2015 Certified.
Methyl 3-oxopentanoate
Methyl 3-oxopentanoate, which is also known as diethyl acetylmalonate or MEAM, Methyl 3-oxopentanoate is commonly used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and flavorings, and it can also Used as a reagent in organic chemical reactions, especially the formation of carbon-carbon bonds through malonate synthesis, the researchers also investigated the potential use of Methyl 3-oxopentanoate in the development of chiral auxiliaries that can aid in the selection of Controlling the stereochemistry of chemical reactions. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 30414-53-0. Pack Sizes: 100 g. Product ID: HY-W010394.
2-acetolactate mutase
Requires ascorbic acid; also converts 2-aceto-2-hydroxybutanoate to 3-hydroxy-3-methyl-2-oxopentanoate. Group: Enzymes. Synonyms: acetolactate mutase; acetohydroxy acid isomerase. Enzyme Commission Number: EC 5.4.99.3. CAS No. 37318-52-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5570; 2-acetolactate mutase; EC 5.4.99.3; 37318-52-8; acetolactate mutase; acetohydroxy acid isomerase. Cat No: EXWM-5570.
Also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-oxopentanoate. Group: Enzymes. Synonyms: 2-oxoisovalerate dehydrogenase; α-ketoisovalerate dehydrogenase. Enzyme Commission Number: EC 1.2.1.25. CAS No. 37211-61-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1131; 2-oxoisovalerate dehydrogenase (acylating); EC 1.2.1.25; 37211-61-3; 2-oxoisovalerate dehydrogenase; α-ketoisovalerate dehydrogenase. Cat No: EXWM-1131.
The product decarboxylates spontaneously to yield 4-methyl-2-oxopentanoate. Group: Enzymes. Synonyms: β-isopropylmalic enzyme; β-isopropylmalate dehydrogenase; threo-Ds-3-isopropylmalate dehydrogenase; 3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase. Enzyme Commission Number: EC 1.1.1.85. CAS No. 9030-97-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0369; 3-isopropylmalate dehydrogenase; EC 1.1.1.85; 9030-97-1; β-isopropylmalic enzyme; β-isopropylmalate dehydrogenase; threo-Ds-3-isopropylmalate dehydrogenase; 3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase. Cat No: EXWM-0369.
Contains thiamine diphosphate. It acts not only on 3-methyl-2-oxobutanaoate, but also on 4-methyl-2-oxopentanoate and (S)-3-methyl-2-oxopentanoate, so that it acts on the 2-oxo acids that derive from the action of transaminases on valine, leucine and isoleucine. It is a component of the multienzyme 3-methyl-2-oxobutanoate dehydrogenase complex in which multiple copies of it are bound to a core of molecules of EC 2.3.1.168, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, which also binds multiple copies of EC 1.8.1.4, dihydrolipoyl dehydrogenase. It does not act on free lipoamide or lipoyllysine, but only on the lipoyllysine residue in EC 2.3.1.168. Group: Enzymes. Synonyms: 2-oxoisocaproate dehydrogenase; 2-oxoisovalerate (lipoate) dehydrogenase; 3-methyl-2-oxobutanoate dehydrogenase (lipoamide); 3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and acceptor-2-methylpropanoylating); α-keto-α-methylvalerate dehydrogenase; α. Enzyme Commission Number: EC 1.2.4.4. CAS No. 9082-72-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1219; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); EC 1.2.4.4; 9082-72-8; 2-oxoisocaproate dehydrogenase; 2-oxoisovalerate (lipo
The enzyme is CoA-dependent and contains thiamine diphosphate and iron-sulfur clusters. Preferentially utilizes 2-oxo-acid derivatives of branched chain amino acids, e.g. 3-methyl-2-oxopentanoate, 4-methyl-2-oxo-pentanoate, 2-oxobutyrate and 3-methylthiopropanamine. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity. For examples of other members of this family, see EC 1.2.7.1, pyruvate synthase, and EC 1.2.7.3, 2-oxoglutarate synthase. Group: Enzymes. Synonyms: 2-ketoisovalerate ferredoxin reductase; 3-methyl-2-oxobutanoate synthase (ferredoxin); VOR; branched-chain ketoacid ferredoxin reductase; branched-chai. Enzyme Commission Number: EC 1.2.7.7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1230; 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); EC 1.2.7.7; 2-ketoisovalerate ferredoxin reductase; 3-methyl-2-oxobutanoate synthase (ferredoxin); VOR; branched-chain ketoacid ferredoxin reductase; branched-chain oxo acid ferredoxin reductase; keto-valine-ferredoxin oxidoreductase; ketoisovalerate ferredoxin reductase; 2-oxoisovalerate ferredoxin reductase. Cat No: EXWM-1230.
3'-O-Levulinoyl-N-benzoyl-2'-deoxyguanosine
3'-O-Levulinoyl-N-benzoyl-2'-deoxyguanosine is a protected nucleotide derivative/building block. Synonyms: 2'-Deoxy-N-isobutyrylguanosine 3'-Levulinate; 3'-(4-Oxopentanoate) 2'-Deoxy-N-(2-methyl-1-oxopropyl)guanosine. CAS No. 93134-41-9. Molecular formula: C19H25N5O7. Mole weight: 435.43.
3-oxoacid CoA-transferase
Acetoacetate and, more slowly, 3-oxopropanoate, 3-oxopentanoate, 3-oxo-4-methylpentanoate or 3-oxohexanoate can act as acceptors; malonyl-CoA can act instead of succinyl-CoA. Group: Enzymes. Synonyms: 3-oxoacid coenzyme A-transferase; 3-ketoacid CoA-transferase; 3-ketoacid coenzyme A transferase; 3-oxo-CoA transferase; 3-oxoacid CoA dehydrogenase; acetoacetate succinyl-CoA transferase; acetoacetyl coenzyme A-succinic thiophorase; succinyl coenzyme A-acetoacetyl coenzyme A-transferase; succinyl-CoA transferase. Enzyme Commission Number: EC 2.8.3.5. CAS No. 9027-43-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3423; 3-oxoacid CoA-transferase; EC 2.8.3.5; 9027-43-4; 3-oxoacid coenzyme A-transferase; 3-ketoacid CoA-transferase; 3-ketoacid coenzyme A transferase; 3-oxo-CoA transferase; 3-oxoacid CoA dehydrogenase; acetoacetate succinyl-CoA transferase; acetoacetyl coenzyme A-succinic thiophorase; succinyl coenzyme A-acetoacetyl coenzyme A-transferase; succinyl-CoA transferase. Cat No: EXWM-3423.
5-Aminolevulinic Acid Methyl Ester Hydrochloride. Group: Biochemicals. Alternative Names: 5-Amino-4-oxopentanoic Acid Methyl Ester Hydrochloride (1:1); Methyl 5-Amino-4-oxopentanoate Hydrochloride; Methyl 5-Aminolevulinate Hydrochloride; Methyl ALA Ester Hydrochloride; Methyl Aminolevulinate Hydrochloride; Metvix; P 1202; δ-Aminolevulinic Acid Methyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 79416-27-6. Pack Sizes: 1g. Molecular Formula: C6H12ClNO3, Molecular Weight: 181.62. US Biological Life Sciences.
Worldwide
5'-Levulinyl-2'-deoxythymidine
5'-Levulinyl-2'-deoxythymidine, a derivative of thymidine, has demonstrated tremendous promise in antiviral therapy through its proven ability to combat HIV-1. Thanks to its unique properties inhibiting reverse transcriptase, it has been identified as a potential critical intervention in HIV-1 infections, providing hope in a world desperately in need of innovative solutions for containing this terrible epidemic. Synonyms: SCHEMBL5179276; 5'-Levulinyl-2'-deoxythymidine; ((2R,3S,5R)-3-Hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl 4-oxopentanoate. Grades: ≥ 98% by HPLC. Molecular formula: C15H20N2O7. Mole weight: 340.33.
5'-O-DMT-3'-O-levulinyl-2'-deoxyadenosine
It is used for conjugation. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-3'-O-levulinyl-2'-deoxyadenosine; [(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-3-yl] 4-oxopentanoate. Grades: ≥95%. CAS No. 2072145-67-4. Molecular formula: C36H37N5O7. Mole weight: 651.71.
5'-O-Levulinoylthymidine 3'-CE phosphoramidite
5'-O-Levulinoylthymidine 3'-CE phosphoramidite, an indispensable asset harnessed within the ever-evolving realms of the biomedical sector, emanates a profound influence upon the synthesis of tailored oligonucleotides. Reverberating as a catalyst for innovation, its innate ability to bestow a 5'-O-levulinoyl modification, combined with its role as a safeguarding entity during solid-phase synthesis, elicits transformative outcomes. Unveiling an extensive repertoire, this wondrous creation orchestrates a symphony of advancements in targeted drug delivery, gene therapy, and the diagnostic landscape. Synonyms: ( (2R, 3S, 5R)-3- ( ( (2-Cyanoethoxy) (diisopropylamino)phosphanyl)oxy)-5- (5-methyl-2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)tetrahydrofuran-2-yl)methyl 4-oxopentanoate. CAS No. 581076-14-4. Molecular formula: C24H37N4O8P. Mole weight: 540.55.
Alectinib Impurity 5
Alectinib Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 4-(4-ethyl-3-iodophenyl)-4-methyl-3-oxopentanoate. CAS No. 1256584-74-3. Molecular formula: C18H25IO3. Mole weight: 416.29. Catalog: APB1256584743.
Boc-Glu(OBzl)-Gly-Arg-AMC HCl
Substrate for coagulation factors IXa and XIIa as well as for trypsin and soybean trypsin-like enzyme. Synonyms: benzyl (4S)-5-[[2-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoate hydrochloride. Grades: ≥ 96% (HPLC). CAS No. 133448-22-3. Molecular formula: C35H45N7O9·HCl. Mole weight: 744.24.
Acts on a number of 2-oxo acids, with a high affinity towards branched-chain substrates. The aldehyde formed may be enzyme-bound, and may be an intermediate in the bacterial system for the biosynthesis of branched-chain fatty acids. Group: Enzymes. Synonyms: branched-chain oxo acid decarboxylase; branched-chain α-keto acid decarboxylase; branched-chain keto acid decarboxylase; BCKA; (3S)-3-methyl-2-oxopentanoate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.72. CAS No. 63653-19-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4820; branched-chain-2-oxoacid decarboxylase; EC 4.1.1.72; 63653-19-0; branched-chain oxo acid decarboxylase; branched-chain α-keto acid decarboxylase; branched-chain keto acid decarboxylase; BCKA; (3S)-3-methyl-2-oxopentanoate carboxy-lyase. Cat No: EXWM-4820.
Calcium 3-methyl-2-oxovalerate
Calcium 3-methyl-2-oxovalerate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Alpha-ketoisoleucine calcium salt. Product Category: Heterocyclic Organic Compound. Appearance: White to off-white solid. CAS No. 66872-75-1. Molecular formula: C12H18CaO6. Mole weight: 298.35. Purity: 0.98. IUPACName: Calcium;3-methyl-2-oxopentanoate. Canonical SMILES: CCC(C)C(=O)C(=O)[O-].CCC(C)C(=O)C(=O)[O-].[Ca+2]. Product ID: ACM66872751. Alfa Chemistry ISO 9001:2015 Certified. Categories: calcium 3-methyl-2-oxopentanoate.
D-2-hydroxyacid dehydrogenase (NAD+)
The enzymes, characterized from bacteria (Peptoclostridium difficile, Enterococcus faecalis and from lactic acid bacteria) prefer substrates with a main chain of 5 carbons (such as 4-methyl-2-oxopentanoate) to those with a shorter chain. It also utilizes phenylpyruvate. The enzyme from the halophilic archaeon Haloferax mediterranei prefers substrates with a main chain of 3-4 carbons (pyruvate and 2-oxobutanoate). cf. EC 1.1.1.272, (D)-2-hydroxyacid dehydrogenase (NADP+). Group: Enzymes. Synonyms: LdhA; HdhD; D-2-hydroxyisocaproate dehydrogenase; R-HicDH; D-HicDH; (R)-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase; (R)-2-hydroxyisocaproate dehydrogenase; D-mandelate dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.1.1.345. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0260; D-2-hydroxyacid dehydrogenase (NAD+); EC 1.1.1.345; LdhA; HdhD; D-2-hydroxyisocaproate dehydrogenase; R-HicDH; D-HicDH; (R)-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase; (R)-2-hydroxyisocaproate dehydrogenase; D-mandelate dehydrogenase (ambiguous). Cat No: EXWM-0260.
D-2-hydroxyacid dehydrogenase (NADP+)
This enzyme, characterized from the halophilic archaeon Haloferax mediterranei and the mold Aspergillus oryzae, catalyses a stereospecific reduction of 2-oxocarboxylic acids into the corresponding D-2-hydroxycarboxylic acids. The enzyme prefers substrates with a main chain of 5 carbons (such as 4-methyl-2-oxopentanoate) to those with a shorter chain, and can use NADH with much lower efficiency. cf. EC 1.1.1.345, (D)-2-hydroxyacid dehydrogenase (NAD+). Group: Enzymes. Synonyms: ddh (gene name). Enzyme Commission Number: EC 1.1.1.272. CAS No. 81210-65-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0179; D-2-hydroxyacid dehydrogenase (NADP+); EC 1.1.1.272; 81210-65-3; ddh (gene name). Cat No: EXWM-0179.
Dl-alpha-keto-beta-methylvaleric acid sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DL-alpha-keto-beta-methylvaleric acid sodium salt;DL-3-Methyl-2-oxovaleric acid. Product Category: Heterocyclic Organic Compound. CAS No. 66872-74-0. Molecular formula: C6H9NaO3. Mole weight: 152.1. Purity: 0.96. IUPACName: sodium 3-methyl-2-oxopentanoate. Canonical SMILES: CCC(C)C(=O)C(=O)[O-].[Na+]. ECNumber: 223-063-8. Product ID: ACM66872740. Alfa Chemistry ISO 9001:2015 Certified.
Ethyl 5-(3-bromo-4-methylphenyl)-5-oxovalerate
Ethyl 5-(3-bromo-4-methylphenyl)-5-oxovalerate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ETHYL 5-(3-BROMO-4-METHYLPHENYL)-5-OXOVALERATE. Product Category: Heterocyclic Organic Compound. CAS No. 898776-84-6. Molecular formula: C14H17BrO3. Mole weight: 313.19. Purity: 0.96. IUPACName: ethyl 5-(3-bromo-4-methylphenyl)-5-oxopentanoate. Canonical SMILES: CCOC(=O)CCCC(=O)C1=CC(=C(C=C1)C)Br. Density: 1.308g/cm³. Product ID: ACM898776846. Alfa Chemistry ISO 9001:2015 Certified.
Ethyl 6-O-benzyl-2-deoxy-4-O-Fmoc-3-O-levulinoyl-2-trichloroacetamido-b-D-thioglucopyranoside is a cutting-edge biomedical product, serving as a potent inhibitor of select enzymes which makes it greatly aid in drug discovery and development. Synonyms: (2R,3S,4R,5R,6S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)oxy)-2-((benzyloxy)methyl)-6-(ethylthio)-5-(2,2,2-trichloroacetamido)tetrahydro-2H-pyran-4-yl 4-oxopentanoate; 1416144-22-3; |A-D-Glucopyranoside, ethyl 2-deoxy-6-O-(phenylmethyl)-1-thio-2-[(2,2,2-trichloroacetyl)amino]-, 4-(9H-fluoren-9-ylmethyl carbonate) 3-(4-oxopentanoate); 1416144-54-1. CAS No. 1416144-54-1. Molecular formula: C37H38Cl3NO9S. Mole weight: 779.1.
Ethyl Isobutyrylacetate
Ethyl Isobutyrylacetate is used in the synthesis of piperazine derivatives as possible multireceptor atypical antipsychotics, affecting dopamine and serotonin receptor properties. Also used in the synthesis of pyrazinecarboxamide DGAT1 (diacylglycerol acyltransferase 1) inhibitors used in the treatment of obesity. Group: Biochemicals. Alternative Names: 3-Oxo-4-methylpentanoic Acid Ethyl Ester; 4-Methyl-3-oxo-pentanoic Acid Ethyl Ester; 4-Methyl-3-oxovaleric Acid Ethyl Ester; Ethyl 2-isobutyrylacetate; Ethyl 3-Isopropyl-3-oxopropanoate; Ethyl 3-oxo-4-methylpentanoate; Ethyl 3-Oxo-4-methylvalerate; Ethyl 4-Methyl-3-oxopentanoate; Ethyl 4-Methyl-3-oxovalerate; Ethyl Isobutyrylacetate; Isobutyrylacetic Acid Ethyl Ester; NSC 62029; γ,γ-Dimethylacetoacetic Acid Ethyl Ester; Ethyl 4-Methyl-3-oxopentanoate. Grades: Highly Purified. CAS No. 7152-15-0. Pack Sizes: 5g. US Biological Life Sciences.
H-Glu(otbu)-leu-ome hcl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-GLUTAMIC ACID TERT-BUTYL ESTER-L-LEUCINE METHYL ESTER HYDROCHLORIDE;H-GLU(OTBU)-LEU-OME HCL;(S)-tert-butyl 4-amino-5-((S)-1-methoxy-4-methyl-1-oxopentan-2-ylamino)-5-oxopentanoate hydrochloride;REF DUPL: H-Glu(OtBu)-Leu-OMe HCl. Product Category: Heterocyclic Organic Compound. CAS No. 85101-25-3. Molecular formula: C16H31ClN2O5. Mole weight: 366.88. Purity: 0.96. IUPACName: methyl(2S)-2-[[(2S)-2-amino-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]amino]-4-methylpentanoate;hydrochloride. Canonical SMILES: CC(C)CC(C(=O)OC)NC(=O)C(CCC(=O)OC(C)(C)C)N.Cl. Product ID: ACM85101253. Alfa Chemistry ISO 9001:2015 Certified.
Leucine dehydrogenase from Microorganism
In enzymology, a leucine dehydrogenase (EC 1.4.1.9) is an enzyme that catalyzes the chemical reaction: L-leucine + H2O + NAD+ ? 4-methyl-2-oxopentanoate + NH3 + NADH + H+. The 3 substrates of this enzyme are L-leucine, H2O, and NAD+, whereas its 4 products are 4-methyl-2-oxopentanoate, NH3, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. This enzyme participates in valine, leucine and isoleucine degradation and valine, leucine and isoleucine biosynthesis. Group: Enzymes. Synonyms: EC 1.4.1.9; Leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); L-leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); LeuDH. Enzyme Commission Number: EC 1.4.1.9. CAS No. 9082-71-7. Mole weight: 43 kDa (SDS-PAGE). Activity: >500U/mg protein. Storage: Store at -20°C. Form: White powder, lyophilized. Source: Microorganism. EC 1.4.1.9; Leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); L-leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); LeuDH; LEDH. Cat No: NATE-1715.
Methyl 4,4-dimethoxy-3-oxovalerate,97%. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Methyl 4,4-dimethoxy-3-oxopentanoate, 62759-83-5, Methy l4,4-dimethoxy-3-oxopentanoate, Methyl 4,4-dimethoxy-3-oxovalerate, Methyl4,4-dimethoxy-3-oxopentanoate, AC1NNSR6, ACMC-1B3OG, KSC615S2D, 343587_ALDRICH, CTK5B5921, MolPort-003-930-646, ANW-48281, AKOS015919513, AK-48402, BR-48402, KB-256844, FT-0660495, W7476, A23160, Pentanoic acid,4,4-dimethoxy-3-oxo-,methyl ester. Product Category: Heterocyclic Organic Compound. CAS No. 62759-83-5. Molecular formula: C8H14O5. Mole weight: 190.19. Purity: 0.96. IUPACName: methyl 4,4-dimethoxy-3-oxopentanoate. Canonical SMILES: CC(C(=O)CC(=O)OC)(OC)OC. Density: 1.111 g/mL at 25ºC(lit.). Product ID: ACM62759835. Alfa Chemistry ISO 9001:2015 Certified.
Methyl Aminolevulinate Hydrochloride
Methyl Aminolevulinate Hydrochloride is the methyl ester of Aminolevulinic Acid, which is a precursor of a photosensitizer and also is used as an add on agent for photodynamic therapy. It shows much higher lipophilicity and highly efficient at inducing protoporphyrin IXproduction in cell culture. Synonyms: Methyl 5-amino-4-oxopentanoate hydrochloride; Methyl 5-Aminolevulinate Hydrochloride; 5-Amino-4-oxopentanoic Acid Methyl Ester Hydrochloride. CAS No. 79416-27-6. Molecular formula: C6H12ClNO3. Mole weight: 181.616.
In enzymology, a leucine dehydrogenase (EC 1.4.1.9) is an enzyme that catalyzes the chemical reaction:L-leucine + H2O + NAD+<-> 4-methyl-2-oxopentanoate + NH3 + NADH + H+. The 3 substrates of this enzyme are L-leucine, H2O, and NAD+, whereas its 4 products are 4-methyl-2-oxopentanoate, NH3, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. This enzyme participates in valine, leucine and isoleucine degradation and valine, leucine and isoleucine biosynthesis. Group: Enzymes. Synonyms: leucine dehydrogenase; L-leucine dehydrogenase; L-leucine:NAD+ oxidoreductase (deaminating); LeuDH; EC 1.4.1.9; 9082-71-7. Enzyme Commission Number: EC 1.4.1.9. CAS No. 9082-71-7. Leucine dehydrogenase. Activity: 60-120 units/mg protein (Lowry). Storage: -20°C. Form: lyophilized powder. Source: Bacillus cereus. leucine dehydrogenase; L-leucine dehydrogenase; L-leucine:NAD+ oxidoreductase (deaminating); LeuDH; EC 1.4.1.9; 9082-71-7. Cat No: NATE-0391.
Native Bacillus sp. Leucine dehydrogenase
In enzymology, a leucine dehydrogenase (EC 1.4.1.9) is an enzyme that catalyzes the chemical reaction: L-leucine + H2O + NAD+ <-> 4-methyl-2-oxopentanoate + NH3 + NADH + H+. The 3 substrates of this enzyme are L-leucine, H2O, and NAD+, whereas its 4 products are 4-methyl-2-oxopentanoate, NH3, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. This enzyme participates in valine, leucine and isoleucine degradation and valine, leucine and isoleucine biosynthesis. Applications: This enzyme is useful for enzyme determination of l-leucine and the activity of leucine amino-peptidase. Group: Enzymes. Synonyms: EC 1.4.1.9; Leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); L-leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); LeuDH. Enzyme Commission Number: EC 1.4.1.9. CAS No. 9082-71-7. Leucine dehydrogenase. Mole weight: 245 kDa. Activity: Grade? 20U/mg-solid or more (containing approx. 70% of stabilizers). Stability: Stable at-20°C for at least one year. Appearance: White amorphous powder, lyophilized. Source: Bacillus sp. EC 1.4.1.9; Leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); L-leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); LeuDH. Cat No: DIA-209.
In enzymology, a leucine dehydrogenase (EC 1.4.1.9) is an enzyme that catalyzes the chemical reaction: L-leucine + H2O + NAD+ <-> 4-methyl-2-oxopentanoate + NH3 + NADH + H+. The 3 substrates of this enzyme are L-leucine, H2O, and NAD+, whereas its 4 products are 4-methyl-2-oxopentanoate, NH3, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. This enzyme participates in valine, leucine and isoleucine degradation and valine, leucine and isoleucine biosynthesis. Applications: The enzyme is useful for determination of l-leucine, l-valine or l-isoleucine. Group: Enzymes. Synonyms: EC 1.4.1.9; Leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); L-leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); LeuDH. Enzyme Commission Number: EC 1.4.1.9. CAS No. 9082-71-7. Leucine dehydrogenase. Mole weight: ca. 300,000; Subunit molecular weight : ca. 49,000. Appearance: Lyophilized. Storage: Stable at -20 °C for at least one year. Source: Bacillus stearothermophilus. EC 1.4.1.9; Leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); L-leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); LeuDH. Cat No: NATE-1905.
N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-tert-Butoxycarbonyl-D-glutamic acid gamma-methyl ester. CAS No. 76379-01-6. Molecular formula: C11H19NO6. Mole weight: 0. Purity: 0.95. IUPACName: (2R)-5-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoate. Canonical SMILES: CC(C)(C)OC(=O)NC(CCC(=O)OC)C(=O)[O-]. Product ID: ACM76379016. Alfa Chemistry ISO 9001:2015 Certified. Categories: 112159-16-7.
Pemetrexed-1-methyl Ester
Pemetrexed-1-methyl ester is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed-1-methyl Ester; Pemetrexed Monomethyl Ester 1; SCHEMBL14331358; 1265908-61-9; (4R)-4-{[4-(2-{2-amino-4-oxo-1H,4H,7H- pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-5-methoxy-5- oxopentanoate; Pemetrexed Impurity 1; 1265908-63-1. Grades: 98%. CAS No. 1265908-63-1. Molecular formula: C21H23N5O6. Mole weight: 441.44.
Pemetrexed Tromethamine Amide
Pemetrexed tromethamine amide is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (S)-tert-Butyl 2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-((1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)-5-oxopentanoate. Molecular formula: C28H38N6O8. Mole weight: 586.64.
(R)-citramalate synthase
One of the enzymes involved in a novel pyruvate pathway for isoleucine biosynthesis that is found in some, mainly archaeal, bacteria. The enzyme can be inhibited by isoleucine, the end-product of the pathway, but not by leucine. The enzyme is highly specific for pyruvate as substrate, as the 2-oxo acids 3-methyl-2-oxobutanoate, 2-oxobutanoate, 4-methyl-2-oxopentanoate, 2-oxohexanoate and 2-oxoglutarate cannot act as substrate. Group: Enzymes. Synonyms: CimA. Enzyme Commission Number: EC 2.3.1.182. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2124; (R)-citramalate synthase; EC 2.3.1.182; CimA. Cat No: EXWM-2124.
(S)-tert-Butyl 5-(((R)-1-(tert-Butoxy)-3-mercapto-1-oxopropan-2-yl)amino)-2-((tert-butoxycarbonyl)amino)-5-oxopentanoate is an intermediate in the synthesis of L-γ-Glutamyl-(S)-Allyl-Cysteine, which is an extract from garlic used in the production of inflammatory mediators. Synonyms: 2-Methyl-2-propanyl (2S)-2-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-5-({(2R)-1-[(2-methyl-2-propanyl)oxy]-1-oxo-3-sulfanyl-2-propanyl}amino)-5-oxopentanoate. CAS No. 2112809-06-8. Molecular formula: C21H38N2O7S. Mole weight: 462.60.
(S)-tert-Butyl 5-(((R)-3-(Allylthio)-1-(tert-butoxy)-1-oxopropan-2-yl)amino)-2-((tert-butoxycarbonyl)amino)-5-oxopentanoate is an intermediate in the synthesis of L-γ-Glutamyl-(S)-Allyl-Cysteine, which is an extract from garlic used in the production of inflammatory mediators. Synonyms: (6S,11R)-2,2-Dimethyl-4,9-dioxo-3-oxa-13-thia-5,10-diazahexadec-15-ene-6,11-dicarboxylate bis(2-methyl-2-propanyl); Bis(2-methyl-2-propanyl) (6S,11R)-2,2-dimethyl-4,9-dioxo-3-oxa-13-thia-5,10-diazahexadec-15-ene-6,11-dicarboxylate. Molecular formula: C24H42N2O7S. Mole weight: 502.66.
Z-LEHD-FMK
Z-LEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-9. Synonyms: Caspase-9 Inhibitor; Methyl (4S) -5-[[ (2S) -1-[[ (3S) -5-fluoro-1-methoxy-1, 4-dioxopentan-3-yl]amino]-3- (1H-imidazol-5-yl) -1-oxopropan-2-yl]amino]-4-[[ (2S) -4-methyl-2- (phenylmethoxycarbonylamino) pentanoyl]amino]-5-oxopentanoate; 2, 2, 2-trifluoroacetic acid. CAS No. 524746-03-0. Molecular formula: C34H44F4N6O12. Mole weight: 804.74.
z-Val-dl-asp-fluoromethylketone
z-Val-dl-asp-fluoromethylketone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBL23453, Z-VAL-DL-ASP -FLUOROMETHYLKETONE, 582317-87-1. Product Category: Heterocyclic Organic Compound. CAS No. 582317-87-1. Molecular formula: C19H25FN2O6. Mole weight: 396.410003 [g/mol]. Purity: 0.96. IUPACName: methyl 5-fluoro-3-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]-4-oxopentanoate. Product ID: ACM582317871. Alfa Chemistry ISO 9001:2015 Certified. Categories: 582316-00-5.
Intermediate in the preparation of an Atorvastatin impurity. Group: Biochemicals. Alternative Names: 2-[2-(2-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic Acid Phenylamide. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
2-Methyl-3-oxopentanoic Acid Methyl Ester
2-Methyl-3-oxopentanoic Acid Methyl Ester is an intermediate in the synthesis of antiproliferative polyketide (+)-R-aureothin. Group: Biochemicals. Grades: Highly Purified. CAS No. 17422-12-7. Pack Sizes: 50mg, 100mg. Molecular Formula: C7H12O3. US Biological Life Sciences.
An Atorvastatin intermediate. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic Acid Phenylamide. Grades: Highly Purified. CAS No. 125971-96-2. Pack Sizes: 1g. US Biological Life Sciences.
An deuterated intermediate of deuterated Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: 2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-d5-ethyl]-4-methyl-3-oxopentanoic Acid Phenylamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
5-(2,4-Dimethylphenyl)-3-methyl-5-oxovaleric acid
5-(2,4-Dimethylphenyl)-3-methyl-5-oxovaleric acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(2,4-DIMETHYLPHENYL)-3-METHYL-5-OXOVALERIC ACID, 92864-22-7, CTK5H1786, AKOS006167818, AG-H-80070, KB-195557. Product Category: Heterocyclic Organic Compound. CAS No. 92864-22-7. Molecular formula: C14H18O3. Mole weight: 234.29776. Purity: 0.96. IUPACName: 5-(2,4-dimethylphenyl)-3-methyl-5-oxopentanoic acid. Canonical SMILES: CC1=CC(=C(C=C1)C(=O)CC(C)CC(=O)O)C. Density: 1.092g/cm³. Product ID: ACM92864227. Alfa Chemistry ISO 9001:2015 Certified.
5-(2-Methoxy-5-methylphenyl)-5-oxovaleric acid
5-(2-Methoxy-5-methylphenyl)-5-oxovaleric acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(2-METHOXY-5-METHYLPHENYL)-5-OXOVALERIC ACID, 71472-14-5, AG-G-80007, CTK5D4236, AKOS009818490, KB-195660. Product Category: Heterocyclic Organic Compound. CAS No. 71472-14-5. Molecular formula: C13H16O4. Mole weight: 236.27007. Purity: 0.96. IUPACName: 5-(2-methoxy-5-methylphenyl)-5-oxopentanoic acid. Canonical SMILES: CC1=CC(=C(C=C1)OC)C(=O)CCCC(=O)O. Density: 1.15g/cm³. Product ID: ACM71472145. Alfa Chemistry ISO 9001:2015 Certified.
5-(3-Bromo-4-methylphenyl)-5-oxovaleric acid
5-(3-Bromo-4-methylphenyl)-5-oxovaleric acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(3-BROMO-4-METHYLPHENYL)-5-OXOVALERIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 898767-16-3. Molecular formula: C12H13BrO3. Mole weight: 285.13. Purity: 0.96. IUPACName: 5-(3-bromo-4-methylphenyl)-5-oxopentanoic acid. Canonical SMILES: CC1=C(C=C(C=C1)C(=O)CCCC(=O)O)Br. Density: 1.443g/cm³. Product ID: ACM898767163. Alfa Chemistry ISO 9001:2015 Certified.
5-(4-Bromo-2-methylphenyl)-5-oxovaleric acid
5-(4-Bromo-2-methylphenyl)-5-oxovaleric acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(4-BROMO-2-METHYLPHENYL)-5-OXOVALERIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 898767-31-2. Molecular formula: C12H13BrO3. Mole weight: 285.13. Purity: 0.96. IUPACName: 5-(4-bromo-2-methylphenyl)-5-oxopentanoic acid. Canonical SMILES: CC1=C(C=CC(=C1)Br)C(=O)CCCC(=O)O. Density: 1.443g/cm³. Product ID: ACM898767312. Alfa Chemistry ISO 9001:2015 Certified.
5-(4-Fluoro-3-methylphenyl)-5-oxovaleric acid
5-(4-Fluoro-3-methylphenyl)-5-oxovaleric acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(4-FLUORO-3-METHYLPHENYL)-5-OXOVALERIC ACID;OTAVA-BB 1043541. Product Category: Heterocyclic Organic Compound. CAS No. 898765-95-2. Molecular formula: C12H13FO3. Mole weight: 224.23. Purity: 0.96. IUPACName: 5-(4-fluoro-3-methylphenyl)-5-oxopentanoic acid. Canonical SMILES: CC1=C(C=CC(=C1)C(=O)CCCC(=O)O)F. Density: 1.208g/cm³. Product ID: ACM898765952. Alfa Chemistry ISO 9001:2015 Certified.
5-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-5-oxopentanoic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: VH 032 amide-alkylC3-acid. Product Category: E3 Ligase Ligand-Linker. CAS No. 2172819-73-5. Molecular formula: C27H36N4O6S. Mole weight: 544.663. Purity: 0.95. IUPACName: 5-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid. Product ID: PR2172819735. Alfa Chemistry ISO 9001:2015 Certified.
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