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| Product | Description | |
|---|---|---|
| mevalonate 3-kinase | Mevalonate 3-kinase and mevalonate-3-phosphate-5-kinase (EC 2.7.1.186) act sequentially in an alternate mevalonate pathway in the archaeon Thermoplasma acidophilum. Mevalonate 3-kinase is different from mevalonate kinase, EC 2.7.1.36, which transfers phosphate to position 5 of (R)-mevalonate and is part of the classical mevalonate pathway in eukaryotes and archaea. Group: Enzymes. Synonyms: ATP:(R)-MVA 3-phosphotransferase. Enzyme Commission Number: EC 2.7.1.185. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3017; mevalonate 3-kinase; EC 2.7.1.185; ATP:(R)-MVA 3-phosphotransferase. Cat No: EXWM-3017. |  |
| mevalonate-3-phosphate 5-kinase | Mevalonate 3-kinase (EC 2.7.1.185) and mevalonate-3-phosphate-5-kinase act sequentially in an alternate mevalonate pathway in the archaeon Thermoplasma acidophilum. Group: Enzymes. Enzyme Commission Number: EC 2.7.1.186. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3018; mevalonate-3-phosphate 5-kinase; EC 2.7.1.186. Cat No: EXWM-3018. | |
| mevalonate kinase | CTP, GTP and UTP can also act as donors. Group: Enzymes. Synonyms: mevalonate kinase (phosphorylating); mevalonate phosphokinase; mevalonic acid kinase; mevalonic kinase; mevalonate 5-phosphotransferase MVA kinase; ATP:mevalonate 5-phosphotransferase. Enzyme Commission Number: EC 2.7.1.36. CAS No. 9026-52-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3067; mevalonate kinase; EC 2.7.1.36; 9026-52-2; mevalonate kinase (phosphorylating); mevalonate phosphokinase; mevalonic acid kinase; mevalonic kinase; mevalonate 5-phosphotransferase MVA kinase; ATP:mevalonate 5-phosphotransferase. Cat No: EXWM-3067. | |
| diphosphomevalonate decarboxylase | This enzyme converts mevalonate 5-diphosphate (MVAPP) to isopentenyl diphosphate (IPP) through ATP dependent decarboxylation. This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. Group: Enzymes. Synonyms: pyrophosphomevalonate decarboxylase; mevalonate-5-pyrophosphate decarboxylase; pyrophosphomevalonic acid decarboxylase; 5-pyrophosphomevalonate decarboxylase; mevalonate 5-diphosphate decarboxylase; ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating). Enzyme Commission Number: EC 4.1.1.33. CAS No. 9024-66-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4777; diphosphomevalonate decarboxylase; EC 4.1.1.33; 9024-66-2; pyrophosphomevalonate decarboxylase; mevalonate-5-pyrophosphate decarboxylase; pyrophosphomevalonic acid decarboxylase; 5-pyrophosphomevalonate decarboxylase; mevalonate 5-diphosphate decarboxylase; ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating). Cat No: EXWM-4777. | |
| phosphomevalonate decarboxylase | The enzyme is part of the mevalonate pathway in archaea. Group: Enzymes. Enzyme Commission Number: EC 4.1.1.99. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4849; phosphomevalonate decarboxylase; EC 4.1.1.99. Cat No: EXWM-4849. | |
| phosphomevalonate kinase | Phosphomevalonate kinase is an enzyme (EC 2.7.4.2) in the mevalonate pathway. Group: Enzymes. Synonyms: ATP:5-phosphomevalonate phosphotransferase; 5-phosphomevalonate kinase; mevalonate phosphate kinase; mevalonate-5-phosphate kinase; mevalonic acid phosphate kinase. Enzyme Commission Number: EC 2.7.4.2. CAS No. 9026-46-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3201; phosphomevalonate kinase; EC 2.7.4.2; 9026-46-4; ATP:5-phosphomevalonate phosphotransferase; 5-phosphomevalonate kinase; mevalonate phosphate kinase; mevalonate-5-phosphate kinase; mevalonic acid phosphate kinase. Cat No: EXWM-3201. | |
| 2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester | 2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C32H37NO4. Mole weight: 499.64. |  |
| 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester | 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Methyl 2-cyclopropyl-4-phenylquinoline-3-carboxylate; 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester; DTXSID00857071; AKOS022175172; SB72967; Methyl2-cyclopropyl-4-phenylquinoline-3-carboxylate. CAS No. 868536-53-2. Molecular formula: C20H17NO2. Mole weight: 303.35. | |
| (2-Cyclopropyl-4-phenylquinolin-3-yl)methanol | (2-Cyclopropyl-4-phenylquinolin-3-yl)methanol is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (2-CYCLOPROPYL-4-PHENYLQUINOLIN-3-YL)METHANOL; MFCD28384714; SY320331; (2-Cyclopropyl-4-phenyl-3-quinolyl)methanol; F86792. Molecular formula: C19H17NO. Mole weight: 275.34. | |
| 2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde | 2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: 2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde; 2153433-59-9. Grades: 98%. CAS No. 2153433-59-9. Molecular formula: C19H15NO. Mole weight: 273.33. | |
| (3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt | (3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (βR,δS)-6-Cyclopropyl-10-fluoro-7,8-dihydro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid Sodium Salt. Molecular formula: C25H23FNNaO4. Mole weight: 443.44. | |
| (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt | (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Defluoro Pitavastatin. Molecular formula: C25H24NNaO4. Mole weight: 425.45. | |
| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase | An iron-sulfur protein that contains either a [3Fe-4S] or a [4Fe-4S] cluster. This enzyme forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase. This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis. This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts. The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and dimethylallyl diphosphate. Group: Enzymes. Synonyms: isopentenyl-diphosphate:NADP+ oxidoreductase; LytB; (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase; HMBPP reductase; IspH; LytB/IspH. Enzyme Commission Number: EC 1.17.7.4. CAS No. 512789-14-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1099; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase; EC 1.17.7.4; 512789-14-9; isopentenyl-diphosphate:NADP+ oxidoreductase; LytB; (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase; HMBPP reductase; IspH; LytB/IspH. Cat No: EXWM-1099. | |
| (5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Sodium Salt | (5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Sodium Salt is one of pitavastatin derivatives. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: sodium (S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-5-hydroxy-3-oxohept-6-enoate; sodium (E,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-5-hydroxy-3-oxo-hept-6-enoate. Molecular formula: C25H21FNNaO4. Mole weight: 441.43. | |
| 6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine | 6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine is one of Pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: 9-cyclopropyl-15-fluoro-8-azatetracyclo; Pitavastatin Impurity 3 (PP-3). Grades: 98%. CAS No. 1187966-94-4. Molecular formula: C20H16FN. Mole weight: 289.35. | |
| 6-Cyclopropyl-10-fluorobenzo[k]phenanthridine | 6-Cyclopropyl-10-fluorobenzo[k]phenanthridine is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin Impurity 4 (PP-4). Grades: 98%. CAS No. 1187966-95-5. Molecular formula: C20H14FN. Mole weight: 287.33. | |
| 8-Hydroxy Pitavastatin | 8-Hydroxy Pitavastatin is one of Pitavastatin metabolites. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-8-hydroxy-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid; (3R,5S,6E)-7-hydroxy-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid; Pitavastatin 8'-Hydroxy Impurity. Grades: ≥90%. CAS No. 224320-09-6. Molecular formula: C25H24FNO5. Mole weight: 437.46. | |
| Acetoacetyl-CoA | Acetoacetyl-CoA is a derivative of CoA. In the mevalonate pathway, Acetoacetyl-CoA is a precursor of HMG-CoA, and a precursor of poly-beta-hydroxybutyrate. Synonyms: S-Acetoacetate Coenzyme A; Acetoacetylcoenzyme A; S-Acetoacetyl-CoA. Grades: 95%. CAS No. 1420-36-6. Molecular formula: C25H40N7O18P3S. Mole weight: 851.61. | |
| acetoacetyl-CoA synthase | The enzyme from the soil bacterium Streptomyces sp. CL190 produces acetoacetyl-CoA to be used for mevalonate production via the mevalonate pathway.Unlike the homologous EC 2.3.1.180 (β-ketoacyl-[acyl-carrier-protein] synthase III), this enzyme does not accept malonyl-[acyl-carrier-protein] as a substrate. Group: Enzymes. Synonyms: NphT7. Enzyme Commission Number: EC 2.3.1.194. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2137; acetoacetyl-CoA synthase; EC 2.3.1.194; NphT7. Cat No: EXWM-2137. | |
| Apomine | Apomine (SR-45023A) is an antineoplastic agent that inhibits the mevalonate/isoprenoid pathway in cholesterol synthesis. Apomine can accelerate the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR). Apomine can also inhibit the growth of various types of cancer cells, including lung cancer, colon cancer, breast cancer, and skin cancer. In addition, Apomine is able to induce apoptosis in tumor cell lines derived from leukemia, colon cancer, liver cancer, ovarian cancer, and breast cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR-45023A; SR 9223i; SK&F-99085. CAS No. 126411-13-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-19671. |  |
| Chlorothricin | Chlorothricin is produced by the strain of Streptomyces antibioticus Tu 99. Related to kijanimicin, saccharocarcins, tetrocarcins and versipelostatin. It inhibits cholesterol biosynthesis from mevalonate, and inhibits pyruvate carboxylases purified from rat liver, chicken liver and azotobacter vinelandii. Synonyms: (4S, 4aS, 6aR, 11E, 12aR, 15R, 16aS, 21aR, 21bR)-4-[[4-O-[3-O-(3-Chloro-6-methoxy-2-methylbenzoyl)-2, 6-dideoxy-β-D-arabino-hexopyranosyl]-2, 6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1, 2, 3, 4, 4a, 6a, 7, 8, 9, 10, 12a, 15, 16, 21, 21a, 21b-hexadecahydro-22-hydroxy-15, 21a-dimethyl-18, 21-dioxo-18H-16a, 19-metheno-16aH-benzo[e]naphtho[2, 1-m][1, 4]dioxacyclopentadecin-14-carboxylic Acid; [4S-(4R*, 4aR*, 6aS*, 11E, 12aS*, 15S*, 16aR*, 21aS*, 21bS*)]-4-[[4-O-[3-O-(3-Chloro-6-methoxy-2-methylbenzoyl)-2, 6-dideoxy-β-D-arabino-hexopyranosyl]-2, 6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1, 2, 3, 4, 4a, 6a, 7, 8, 9, 10, 12a, 15, 16, 21, 21a, 21b-hexadecahydro-22-hydroxy-15, 21a-dimethyl-18, 21-dioxo-18H-16a, 19-metheno-16aH-benzo[e]naphtho[2, 1-m][1, 4]dioxacyclopentadecin-14-carboxylic Acid. Grades: >99% by HPLC. CAS No. 34707-92-1. Molecular formula: C50H63ClO16. Mole weight: 955.48. | |
| Chlorothricin (Antibiotic K 818A) | The tetronic acid, chlorothricin is an unusual macrocyclic antibiotic from a Streptomyces sp. It shows inhibitory activity against cholesterol biosynthesis from mevalonate and inhibits pyruvate carboxylases purified from rat liver, chicken liver and Azotobacter vinelandii. Group: Biochemicals. Alternative Names: Antibiotic K 818A. Grades: Highly Purified. CAS No. 34707-92-1. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) | An iron-sulfur protein found in plant chloroplasts and cyanobacteria that contains a [4Fe-4S] cluster. Forms part of an alternative non-mevalonate pathway for isoprenoid biosynthesis. Bacteria have a similar enzyme that uses flavodoxin rather than ferredoxin (cf. EC 1.17.7.3). The enzyme from the plant Arabidopsis thaliana is active with photoreduced 5-deazaflavin but not with flavodoxin. Group: Enzymes. Synonyms: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ambiguous); (E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:protein-disulfide oxidoreductase (hydrating) (incorrect); (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (ambiguous); gcpE (gene name); ISPG (gene name); (E)-4-hydroxy-3-methylbut-2-eny. Enzyme Commission Number: EC 1.17.7.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1096; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin); EC 1.17.7.1; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ambiguous); (E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:protein-disulfide oxidoreductase (hydrating) (incorrect); (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (ambiguous); gcpE (gene name); ISPG (gene name); (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase. Cat No: EXWM-1096. | |
| (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) | A bacterial iron-sulfur protein that contains a [4Fe-4S] cluster. Forms part of an alternative non-mevalonate pathway for isoprenoid biosynthesis that is found in most bacteria. Plants and cyanobacteria have a similar enzyme that utilizes ferredoxin rather than flavodoxin (cf. EC 1.17.7.1). Group: Enzymes. Synonyms: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ambiguous); (E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:protein-disulfide oxidoreductase (hydrating) (incorrect); (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (ambiguous); ispG (gene name). Enzyme Commission Number: EC 1.17.7.3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1098; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin); EC 1.17.7.3; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ambiguous); (E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:protein-disulfide oxidoreductase (hydrating) (incorrect); (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (ambiguous); ispG (gene name). Cat No: EXWM-1098. | |
| Farnesyl pyrophosphate ammonium | Farnesyl pyrophosphate ammonium salt, a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. Farnesyl pyrophosphate ammonium salt is a TRPM2 (TRP Channel) agonist, and activates TRPM2 opening for ion influx. Farnesyl pyrophosphate ammonium salt is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Farnesyl diphosphate ammonium. CAS No. 116057-57-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113037C. | |
| Farnesyl Pyrophosphate Triammonium Salt | Isoprenoid from the intracellular mevalonate pathway used for prenylation of several low molecular mass G proteins, including Ras. Group: Biochemicals. Alternative Names: Diphosphoric Acid P-[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl] Ester Ammonium Salt; (E,E)-Diphosphoric Acid Mono(3,7,11-trimethyl-2,6,10-dodecatrienyl) Ester Triammonium Salt. Grades: Highly Purified. CAS No. 116057-57-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Fosmidomycin sodium salt | Fosmidomycin is an antimalarial and antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces and has been used as an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Synonyms: Antibiotic FR31564; FR31564; P-[3-(formylhydroxyamino)propyl]-phosphonic acid, monosodium salt; (3-(N-Hydroxyformamido)propyl)phosphonic acid sodium salt; Phosphonic acid, (3-(formylhydroxyamino)propyl)-, monosodium salt. Grades: ≥95%. CAS No. 66508-37-0. Molecular formula: C4H9NO5P.Na. Mole weight: 205.08. | |
| FR900098 sodium salt | FR900098 is a derivative of fosmidomycin that displays antimalarial activity. FR900098 is an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Synonyms: (3-(Acetylhydroxyamino)propyl)-phosphonic acid, monosodium salt; BRN 2096083; P-[3-(Acetylhydroxyamino)propyl]-phosphonic acid, monosodium salt. Grades: ≥95%. CAS No. 73226-73-0. Molecular formula: C5H11NO5P·Na. Mole weight: 219.1. | |
| Geranylgeraniol | Geranylgeraniol is an orally acitve vitamin K 2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 24034-73-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W011474. | |
| HMG-CoA | HMG-CoA is an intermediate in the mevalonate pathway. Synonyms: S-(Hydrogen 3-Hydroxy-3-methylglutarate) Coenzyme A; 3-Hydroxy-3-methylglutaryl CoA; 3-Hydroxy-3-methylglutaryl Coenzyme A; Hydroxymethylglutaryl CoA; Hydroxymethylglutaryl Coenzyme A; β-Hydroxy-β-methylglutaryl CoA; β-Hydroxy-β-methylglutaryl-coenzyme A. CAS No. 1553-55-5. Molecular formula: C27H44N7O20P3S. Mole weight: 911.66. | |
| hydroxymethylglutaryl-CoA reductase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-mevalonate:NAD+ oxidoreductase (CoA-acylating). Other names in common use include beta-hydroxy-beta-methylglutaryl coenzyme A reductase, beta-hydroxy-beta-methylglutaryl CoA-reductase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and hydroxymethylglutaryl coenzyme A reductase. Group: Enzymes. Synonyms: β-hydroxy-β-methylglutaryl coenzyme A reductase; β-hydroxy-β-methylglutaryl CoA-reductase; 3-hydroxy-3-methylglutaryl coenzyme A reductase; hydroxymethylglutaryl coenzyme A reductase. Enzyme Commission Number: EC 1.1.1.88. CAS No. 37250-24-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0372; hydroxymethylglutaryl-CoA reductase; EC 1.1.1.88; 37250-24-1; β-hydroxy-β-methylglutaryl coenzyme A reductase; β-hydroxy-β-methylglutaryl CoA-reductase; 3-hydroxy-3-methylglutaryl coenzyme A reductase; hydroxymethylglutaryl coenzyme A reductase. Cat No: EXWM-0372. | |
| hydroxymethylglutaryl-CoA reductase (NADPH) | The enzyme is inactivated by EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} and reactivated by EC 3.1.3.47 {[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase}. Group: Enzymes. Synonyms: hydroxymethylglutaryl coenzyme A reductase (reduced nicotinamide adenine dinucleotide phosphate); 3-hydroxy-3-methylglutaryl-CoA reductase; β-hydroxy-β-methylglutaryl coenzyme A reductase; hydroxymethylglutaryl CoA reductase (NADPH); S-3-hydroxy-3-methylglutaryl-CoA reductase; NADPH-hydroxymethylglutaryl-CoA reductase; HMGCoA reductase-mevalonate:NA. Enzyme Commission Number: EC 1.1.1.34. CAS No. 9028-35-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0254; hydroxymethylglutaryl-CoA reductase (NADPH); EC 1.1.1.34; 9028-35-7; hydroxymethylglutaryl coenzyme A reductase (reduced nicotinamide adenine dinucleotide phosphate); 3-hydroxy-3-methylglutaryl-CoA reductase; β-hydroxy-β-methylglutaryl coenzyme A reductase; hydroxymethylglutaryl CoA reductase (NADPH); S-3-hydroxy-3-methylglutaryl-CoA reductase; NADPH-hydroxymethylglutaryl-CoA reductase; HMGCoA reductase-mevalonate:NADP-oxidoreductase (acetylating-CoA); 3-hydroxy-3-methylglutaryl CoA reductase (NADPH); hydroxymethylglutaryl-CoA reductase (NADPH2). Cat No: EXWM-0254. | |
| hydroxymethylglutaryl-CoA synthase | In molecular biology, Hydroxymethylglutaryl-CoA synthase or HMG-CoA synthase EC 2.3.3.10 is an enzyme which catalyzes the reaction in which Acetyl-CoA condenses with acetoacetyl-CoA to form 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA). It is the second reaction in the mevalonate-dependent isoprenoid biosynthesis pathway. Group: Enzymes. Synonyms: (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating); 3-hydroxy-3-methylglutaryl CoA synthetase; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl coenzyme A synthetase; 3-hydroxy-3-methylg. Enzyme Commission Number: EC 2.3.3.10. CAS No. 9027-44-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2311; hydroxymethylglutaryl-CoA synthase; EC 2.3.3.10; 9027-44-5; (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating); 3-hydroxy-3-methylglutaryl CoA synthetase; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl coenzyme A synthetase; 3-hydroxy-3-methylglutaryl-CoA synthase; 3-hydroxy-3-methylglutaryl-coenzyme A synthase; β-hydroxy-β-methylglutaryl-CoA synthase; HMG-CoA synthase; acetoacetyl coenzyme A transacetase; hydroxymethylglutaryl coenzyme A synthase; hydroxymethylglutaryl coenzyme A-condensing enzyme. Cat No: EXWM-2311. | |
| isopentenyl phosphate kinase | The enzyme is involved in the mevalonate pathway in Archaea. The activity has also been identified in the plant Mentha piperita (peppermint). It is strictly specific for ATP but can use other phosphate acceptors such as dimethylallyl phosphate, geranyl phosphate, or fosfomycin. Group: Enzymes. Enzyme Commission Number: EC 2.7.4.26. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3208; isopentenyl phosphate kinase; EC 2.7.4.26. Cat No: EXWM-3208. | |
| mevaldate reductase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-mevalonate:NAD+ oxidoreductase. This enzyme is also called mevalonic dehydrogenase. Group: Enzymes. Synonyms: mevalonic dehydrogenase. Enzyme Commission Number: EC 1.1.1.32. CAS No. 9028-33-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0232; mevaldate reductase; EC 1.1.1.32; 9028-33-5; mevalonic dehydrogenase. Cat No: EXWM-0232. | |
| N6-Isopentenyladenosine | N6-Isopentenyladenosine (Riboprine), an RNA modification found in cytokinins, which regulate plant growth/differentiation, and a subset of tRNAs, where it improves the efficiency and accuracy of translation. N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with an interesting anti-melanoma activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Riboprine. CAS No. 7724-76-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg. Product ID: HY-W011209. | |
| Perillyl Alcohol | Perillyl Alcohol, or POH, a monoterpene derived from the mevalonate pathway in plants, induces apoptosis in colon tumor cells. Synonyms: Perillyl alcohol; Perilla alcohol; Perycorolle; POH; perillol; perillic alcohol; [(4S)-4-prop-1-en-2-ylcyclohexen-1-yl]methanol; (-)-p-mentha-1,8-dien-7-ol; (S)-perillyl alcohol; 1-cyclohexene-1-methanol, 4-(1-methylethenyl)-, (4S)-; 4-isopropenyl-cyclohex-1-ene-1-methanol; cyclohex-1-ene-1-methanol, 4(1-methylethenyl); dihydrocuminyl alcohol; NSC 641066; p-mentha-1,8-dien-7-ol; perilla alcohol. Grades: >98%. CAS No. 18457-55-1. Molecular formula: C10H16O. Mole weight: 152.237. | |
| Pitavastatin | Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. IC50: HepG2=5.8 nM. Synonyms: Zypitamag; (3R,5S,6E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic acid; (3R,5S)-3,5-Dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-6-heptenoic acid; Itavastatin; Livalo; NK 104; itavastatinn; NK-104; NK104; P 872441; P-872441; P872441. Grades: > 98%. CAS No. 147511-69-1. Molecular formula: C25H24FNO4. Mole weight: 421.46. | |
| Pitavastatin 1-Phenylethylamide | Pitavastatin 1-Phenylethylamide is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin Impurity. Molecular formula: C33H33FN2O3. Mole weight: 524.62. | |
| Pitavastatin 3-Ether Glucuronide | Pitavastatin 3-Ether Glucuronide is one of pitavastatin metabolites. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: β-D-Glucopyranosiduronic acid, (1R,3S,4E)-1-(carboxymethyl)-5-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-4-penten-1-yl; (1R,3S,4E)-1-(Carboxymethyl)-5-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-4-penten-1-yl β-D-Glucopyranosiduronic Acid; (2R,4S,5E)-1-Carboxy-6-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-4-hydroxy-5-hexen-2-yl β-D-glucopyranosiduronic acid. Grades: ≥95%. CAS No. 224320-11-0. Molecular formula: C31H32FNO10. Mole weight: 597.58. | |
| Pitavastatin (5R)-Oxo Impurity | An impurity of Pitavastatin which inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Grades: > 95%. Molecular formula: C26H24FNO4. Mole weight: 433.48. | |
| Pitavastatin Defuoro Impurity Calcium Salt | An impurity of Pitavastatin which inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Defluoro Pitavastatin Calcium Salt; CS-0164801; 1258947-30-6; monocalcium mono((3R,5S,E)-7-(2-cyclopropyl-4-phenylquinolin-3-yl)-3,5-dihydroxyhept-6-enoate)? (Pitavastatin Impurity pound(c). Grades: > 95%. CAS No. 1258947-30-6. Molecular formula: C50H48N2O8.Ca. Mole weight: 845.03. | |
| Pitavastatin Impurity 13 | Pitavastatin Impurity 13 (Pitavastatin 2,4,6-Triene Impurity) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin 2,4,6-Triene Impurity. Grades: > 95%. CAS No. 2086271-67-0. Molecular formula: C25H20FNO2. Mole weight: 385.43. | |
| Pitavastatin Impurity 14 | Pitavastatin Impurity 14 (Pitavastatin 2-Fluoro Isomer) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin 2-Fluoro Isomer. Grades: > 95%. Molecular formula: C25H24FNO4. Mole weight: 421.46. | |
| Pitavastatin Impurity 15 | Pitavastatin Impurity 15 (Pitavastatin 4,6-Diene Impurity) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3S,4E,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3-hydroxyhepta-4,6-dienoic acid; Pitavastatin 4,6-Diene Impurity. Molecular formula: C25H22FNO3. Mole weight: 403.44. | |
| Pitavastatin Impurity 16 | Pitavastatin Impurity 16 (Pitavastatin 4-Desfluoro 4-Hydroxy Impurity) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin 4-Desfluoro 4-Hydroxy Impurity. Grades: > 95%. Molecular formula: C25H25NO5. Mole weight: 419.47. | |
| Pitavastatin Impurity 18 Sodium Salt | Pitavastatin Impurity 18 Sodium Salt (Pitavastatin N-Oxide Sodium Salt) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-1-oxido-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid, sodium salt (1:1); Pitavastatin N-Oxide Sodium Salt. CAS No. 2276678-27-2. Molecular formula: C25H23FNO5Na. Mole weight: 459.44. | |
| Pitavastatin Impurity 19 Sodium Salt (Mixture of Diastereomers) | Pitavastatin Impurity 19 Sodium Salt (Mixture of Diastereomers) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3R,5S)-5-(3-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)oxiran-2-yl)--dihydroxyhept-6-enoic acid. Molecular formula: C25H23FNO5Na. Mole weight: 459.44. | |
| Pitavastatin Impurity 1 Calcium Salt | Pitavastatin Impurity 1 Calcium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.49. | |
| Pitavastatin Impurity 2 | (3R,5S)-5-(6-Cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (βR,δS)-6-Cyclopropyl-10-fluoro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid; Pitavastatin Impurity 2 (PP-2). Grades: 94%. CAS No. 1187966-93-3. Molecular formula: C25H22FNO4. Mole weight: 419.44. | |
| Pitavastatin Impurity 20 | Pitavastatin Impurity 20 is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Uses: A hmg-coa reductase inhibitor intermediate. Synonyms: (4R-cis)-6-Chloromethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester; tert-butyl syn-(3R,5S)-6-chloro-3,5-(isopropylidenedioxy)-hexanoate; (4R-cis)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid; t-butyl (4R-cis)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxan-4-ylacetate; (4R,6S)-6-(Chloromethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. Grades: 96%. CAS No. 154026-94-5. Molecular formula: C13H23ClO4. Mole weight: 278.77. | |
| Pitavastatin Impurity 22 | Pitavastatin Impurity 22 is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C32H36FNO4. Mole weight: 517.63. | |
| Pitavastatin Impurity 5 | Pitavastatin Impurity 5 is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate; (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester; Pitavastatin Impurity 21. Grades: 98%. CAS No. 147489-06-3. Molecular formula: C32H36FNO4. Mole weight: 517.63. | |
| R-Mevalonic Acid, Lithium Salt | Mevalonic acid is an intermediate in the mevalonate pathway, producing terpenes and steroids. This function provides treatment options metabolic disorders, R-mevalonate accumulates in patients with the autosomal recessively inherited mevalonic acidurias, an inborn error of cholesterol and nonsterol isoprene biosynthesis. Group: Biochemicals. Alternative Names: Lithium (R)-3,5-dihydroxy-3-methylpentanoate, Lithium (R)-3,5-dihydroxy-3-methylvalerate, R-MVA-Li. Grades: Highly Purified. CAS No. 1255502-07-8. Pack Sizes: 10mg. Molecular Formula: C6H11LiO4, Molecular Weight: 154.09. US Biological Life Sciences. | Worldwide |
| (R,R)-Hymeglusin | beta-Lactone antibiotic. Antibacterial and antifungal. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. Mevalonate biosynthesis inhibitor. Group: Biochemicals. Alternative Names: 1233A, F-244, L-659-699. Grades: Highly Purified. CAS No. 29066-42-0. Pack Sizes: 500ug, 1mg, 2.5mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
| Zoledronic Acid | Zoledronic acid induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. Synonyms: Zoledronate, CGP-4244; CGP 4244; CGP4244. Grades: >98%. CAS No. 118072-93-8. Molecular formula: C5H10N2O7P2. Mole weight: 272.09. | |
| 1-Methoxy-4-[(3-methyl-3-buten-1-yl)oxy]benzene | 1-Methoxy-4-[(3-methyl-3-buten-1-yl)oxy]benzene is an intermediate in the synthesis of L-Isomer of Mevalonic acid (M339020), a precursor in the biosynthesis of cholesterol (C432501). Group: Biochemicals. Grades: Highly Purified. CAS No. 169310-73-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C12H16O2. US Biological Life Sciences. | Worldwide |
| 4-(1-Ethoxyethoxy)-2-methyl-1,2-butanediol | 4-(1-Ethoxyethoxy)-2-methyl-1,2-butanediol is an intermediate in the synthesis of Mevalonolactone, which is a key intermediate in the synthesis of vitamin E-related compounds. Synonyms: 1,2-Butanediol, 4-(1-ethoxyethoxy)-2-methyl-. Molecular formula: C9H20O4. Mole weight: 192.25. | |
| 4-(1-Ethoxyethoxy)-2-methyl-1,2-butanediol 1-(4-Methylbenzenesulfonate) | 4-(1-Ethoxyethoxy)-2-methyl-1,2-butanediol 1-(4-Methylbenzenesulfonate) is an intermediate in the synthesis of Mevalonolactone, which is a key intermediate in the synthesis of vitamin E-related compounds. Synonyms: 1,2-Butanediol, 4-(1-ethoxyethoxy)-2-methyl-, 1-(4-methylbenzenesulfonate)-. Molecular formula: C16H26O6S. Mole weight: 346.44. | |
| 4-(1-Ethoxyethoxy)-2-methyl-1-butene | 4-(1-Ethoxyethoxy)-2-methyl-1-butene is an intermediate in the synthesis of Mevalonolactone, which is a key intermediate in the synthesis of vitamin E-related compounds. Synonyms: 1-Butene, 4-(1-ethoxyethoxy)-2-methyl-; 1-Ethoxy-1-[(3-methylbut-3-en-1-yl)oxy]ethane; 2,6-Dimethyl-5,7-dioxa-1-nonene. CAS No. 261378-88-5. Molecular formula: C9H18O2. Mole weight: 158.24. | |
| 5-(1-Ethoxyethoxy)-3-hydroxy-3-methylpentanenitrile | 5-(1-Ethoxyethoxy)-3-hydroxy-3-methylpentanenitrile is an intermediate in the synthesis of Mevalonolactone, which is a key intermediate in the synthesis of vitamin E-related compounds. Synonyms: Pentanenitrile, 5-(1-ethoxyethoxy)-3-hydroxy-3-methyl-. Molecular formula: C10H19NO3. Mole weight: 201.26. | |
| D,L-Mevalonic Acid-d3 Dicyclohexylamine Salt | Labeled Mevalonic Acid. Precursor in the biosynthesis of cholesterol. Occurs in equilibrium with the δ-lactone. Group: Biochemicals. Alternative Names: 3,5-Dihydroxy-3-(methyl-d3) Pentanoic Acid Dicyclohexylamine Salt; Hiochic Acid-d3 Dicyclohexylamine Salt; 3,5-Dihydroxy-3-(methyl-d3)valeric Acid Dicyclohexylamine Salt; 2,4-Dideoxy-3-C-(methyl-d3)pentonic Acid Dicyclohexylamine Salt; Mevalonic Acid-d3 Dicyclohexylamine Salt; (RS)-Mevalonic Acid-d3 Dicyclohexylamine Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| D,L-Mevalonic Acid Dicyclohexylammonium Salt | Precursor in the biosynthesis of cholesterol. Occurs in equilibrium with the δ-lactone. Group: Biochemicals. Alternative Names: 3,5-Dihydroxy-3-(methyl) Pentanoic Acid Dicyclohexylammonium Salt; Hiochic Acid Dicyclohexylammonium Salt; 3,5-Dihydroxy-3-(methyl)valeric Acid Dicyclohexylammonium Salt; MK 91; MVA; MVS; (RS)-Mevalonic Acid Dicyclohexylammonium Salt. Grades: Highly Purified. CAS No. 1215802-31-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| D,L-Mevalonic acid lactone | D,L-Mevalonic acid lactone. Group: Biochemicals. Alternative Names: Tetrahydro-4-hydroxy-4-methyl-2H-pyran-2-one. Grades: Highly Purified. CAS No. 674-26-0. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C6H10O3. US Biological Life Sciences. | Worldwide |
| d,l-Mevalonic acid lactone-d3 | d,l-Mevalonic acid lactone-d3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MEVALONOLACTONE-(METHYL-D3);MEVALONOLACTONE-D3 (METHYL-D3);DL-MEVALONOLACTONE-D3;DL-MEVALONIC-METHYL-D3 LACTONE;D,L--Hydroxy--(methyl-d3)--valerolactone;D,L-Mevalonic Acid Lactone-d3;Mevalonic Lactone-d3;Mevalonolactone-d3. Product Category: Heterocyclic Organic Compound. Appearance: Pale Yellow Oil. CAS No. 61219-76-9. Molecular formula: C6H7D3O3. Mole weight: 133.16. Purity: 99 atom % D. Product ID: ACM61219769. Alfa Chemistry ISO 9001:2015 Certified. |  |
| D,L-Mevalonic Acid Lactone-d3 | A labeled metabolite from endophytes of the medicinal plant Erythrina crista-galli. Group: Biochemicals. Alternative Names: Tetrahydro-4-hydroxy-4-(methyl-d3)-evalonolactone-d3. Grades: Highly Purified. CAS No. 61219-76-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| D,L-Mevalonic Acid Lactone (D,L-b-Hydroxy-b-methyl-?-valerolactone) | A metabolite from endophytes of the medicinal plant Erythrina crista-galli. Group: Biochemicals. Alternative Names: D,L-b-Hydroxy-b-methyl-?-valerolactone. Grades: Highly Purified. CAS No. 674-26-0. Pack Sizes: 500mg, 1g, 2g. US Biological Life Sciences. | Worldwide |
| Dl-Mevalonolactone | Dl-Mevalonolactone. Group: Monomers. Alternative Names: Tetrahydro-4-hydroxy-4-methylpyran-2-one. CAS No. 674-26-0. Pack Sizes: 1 kg. Product ID: 4-Hydroxy-4-methyloxan-2-one. Molecular formula: 130.14. Mole weight: C6H10O3. CC1(CCOC(=O)C1)O. InChI=1S/C6H10O3/c1-6 (8)2-3-9-5 (7)4-6/h8H, 2-4H2, 1H3. JYVXNLLUYHCIIH-UHFFFAOYSA-N. 95%+. |  |
| MC-031 | MC-031, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 10.6×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: O-Demethylchlorothricin. CAS No. 134637-04-0. Molecular formula: C49H61ClO16. Mole weight: 941.45. | |
| MC-032 | MC-032, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 10.5×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: O-Demethylhydroxychlorothricin. CAS No. 134615-17-1. Molecular formula: C49H61ClO17. Mole weight: 957.45. | |
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