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| Product | Description | |
|---|---|---|
| Mitomycin C | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H18N4O5. CAS No. 50-07-7. Prepack ID 17545348-25mg. Molecular Weight 334.33. See USA prepack pricing. |  |
| Mitomycin C | 2mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H18N4O5. CAS No. 50-07-7. Prepack ID 17545348-2mg. Molecular Weight 334.33. See USA prepack pricing. | |
| Mitomycin C | An antitumor antibiotic. It is used as antineoplastic. Group: Biochemicals. Alternative Names: [1aS-(1aα,8 β , 8aα , 8bα ) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; MMC; Ametycine; Mutamycin; Mitonco; Mitoplus. Grades: Highly Purified. CAS No. 50-07-7. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Mitomycin C | Mitomycin C is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. And it has an inhibitory effect on tumors. Uses: Mitomycin c is also available as a a 4% mixture in nacl. see "mitomycin c+nacl" sample coa. Synonyms: Mitiromycin E; Mutamycin; Ametycine; Zilimeisu. Grades: Assay ≥ 970 mg/g Mitomycin. CAS No. 50-07-7. Molecular formula: C15H18N4O5. Mole weight: 334.33. |  |
| Mitomycin C Pure (NaCl-Free) | Supplied as a pure preparation of Mitomycin C. This preparation contains no sodium chloride. Group: Biochemicals. Alternative Names: Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS- (1aa, 8b, 8aa, 8ba) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Molecular Biology Grade. CAS No. 50-07-7. Pack Sizes: 4mg, 12mg, 24mg, 40mg. US Biological Life Sciences. | Worldwide |
| Mitomycin C w/NaCl | Supplied as a preparation of Mitomycin C with sodium chloride in a ratio of 2mg Mitomycin C and 48mg sodium chloride. Group: Biochemicals. Alternative Names: Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS- (1aa, 8b, 8aa, 8ba) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Molecular Biology Grade. CAS No. 50-07-7. Pack Sizes: 2mg. US Biological Life Sciences. | Worldwide |
| 10-Decarbamoyloxy-9-dehydromitomycin B | 10-Decarbamoyloxy-9-dehydromitomycin B is a mitane antibiotic produced by Streptomyces caespitosus KY 2072. It has anti-Gram-positive bacteria and anti-tumor cell activity. Synonyms: Mitomycin H; Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-1,5-dimethyl-8a-hydroxy-6-methoxy-8-methylene-, (1aS-(1a-alpha,8a-alpha,8b-alpha))-. CAS No. 74148-44-0. Molecular formula: C15H16N2O4. Mole weight: 288.30. | |
| 7-Demethoxy-7-amino-9a-O-methylmitomycin | 7-Demethoxy-7-amino-9a-O-methylmitomycin is a mito-mycin antibiotic produced by Streptomyces caespitosus. It has anti-tumor and gram-positive bacteria activity. Synonyms: Mitomycin E. CAS No. 74707-94-1. Molecular formula: C16H20N4O5. Mole weight: 348.35. | |
| (8aS)-8a-Bromoalbomitomycin A | (8aS)-8a-Bromoalbomitomycin A is an intermediate of Mitomycin A. Synonyms: [1S-(1α, 2α, 4β, 5β, 6α, 6aα, 10aS*, 11R*)]-6-[[(Aminocarbonyl)oxy]methyl]-6a-bromo-2, 3, 6, 6a-tetrahydro-5, 8-dimethoxy-9-methyl-1, 2, 5-metheno-1H, 5H-imidazo[2, 1-i]indole-7, 10-dione; [(1R, 3S, 4R, 7R, 8S, 9S)-9-Bromo-7, 11-dimethoxy-12-methyl-10, 13-dioxo-2, 6-diazapentacyclo[7.4.0.01, 6.02, 4.03, 7]tridec-11-en-8-yl]methyl carbamate; 1,2,5-Metheno-1H,5H-imidazo[2,1-i]indole-7,10-dione, 6-[[(aminocarbonyl)oxy]methyl]-6a-bromo-2,3,6,6a-tetrahydro-5,8-dimethoxy-9-methyl-, (2R,5R,6S,6aS,10aR,11S)-. Grades: ≥90%. CAS No. 132830-44-5. Molecular formula: C16H18BrN3O6. Mole weight: 428.23. | |
| 9-Epimitomycin B | 9-Epimitomycin B is an intermediate in the formation of mitomycin B, an antitumor antibiotic. Synonyms: Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-8-(((aminocarbonyl)oxy)methyl)-1,5-dimethyl-8a-hydroxy-6-methoxy-, (1aS-(1a-alpha,8-beta,8a-alpha,8b-alpha))-; 9-epi-Mitomycin B. Grades: 95%. CAS No. 13164-90-4. Molecular formula: C16H19N3O6. Mole weight: 349.34. | |
| Albomitomycin C | Albomitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells. Synonyms: (1S,2S,4S,5R,6S,6aR,10aS,11S)-8-Amino-6-[[(aminocarbonyl)oxy]methyl]-2,3,6,6a-tetrahydro-5-methoxy-9-methyl-1,2,5-metheno-1H,5H-imidazo[2,1-i]indole-7,10-dione; Antibiotic CX 1; [1S-(1α, 2α, 4β, 5β, 6α, 6aα, 10aR*, 11R*)]-8-amino-6-[[(aminocarbonyl)oxy]methyl]-2, 3, 6, 6a-tetrahydro-5-methoxy-9-methyl-1, 2, 5-Metheno-1H, 5H-imidazo[2, 1-i]indole-7, 10-dione; Mitomycin EP Impurity D. Grades: > 95%. CAS No. 111750-67-5. Molecular formula: C15H18N4O5. Mole weight: 334.33. | |
| Decarbamoyl methyl mitomycin A | Decarbamoyl methyl mitomycin A is an impurity of Mitocycin B (M371895), an antitumor antibiotic used as an antineoplastic agent. Group: Biochemicals. Alternative Names: 1, 1a, 2, 8, 8a, 8b-Hexahydro-8-(hydroxymethyl)-6, 8aα-dimethoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; [1aS-(1aα,8 β, 8aα, 8bα)]-1, 1a, 2, 8, 8a, 8b-Hexahydro-8-(hydroxymethyl)-6, 8a-dimethoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Highly Purified. CAS No. 26909-45-5. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Decarbamoylmethylmitomycin A | Decarbamoylmethylmitomycin A is an impurity of Mitocycin B. Mitomycin is a drug which is used for treatment of malignant neoplasm of lip. Synonyms: 1, 1a, 2, 8, 8a, 8b-Hexahydro-8-(hydroxymethyl)-6, 8aα-dimethoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; [1aS-(1aα, 8β, 8aα, 8bα)]-1, 1a, 2, 8, 8a, 8b-Hexahydro-8-(hydroxymethyl)-6, 8a-dimethoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. CAS No. 26909-45-5. Molecular formula: C16H20N2O5. Mole weight: 320.34. | |
| mitomycin 6-O-methyltransferase | The enzyme, characterized from the bacterium Streptomyces lavendulae, is involved in the biosynthesis of the quinone-containing antibiotics mitomycin A and mitomycin B. Group: Enzymes. Synonyms: MmcR; mitomycin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:7-demethylmitomycin-A 7-O-methyltransferase (incorrect). Enzyme Commission Number: EC 2.1.1.316. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1924; mitomycin 6-O-methyltransferase; EC 2.1.1.316; MmcR; mitomycin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:7-demethylmitomycin-A 7-O-methyltransferase (incorrect). Cat No: EXWM-1924. |  |
| Mitomycin A | Mitomycin A is a bacterial metabolite. Mitomycin A reduces migration inhibition factor ( MIF ) production and can be used for the research of cancer [1]. Uses: Scientific research. Group: Natural products. CAS No. 4055-39-4. Pack Sizes: 500 μg. Product ID: HY-130332. |  |
| Mitomycin A | Mitomycin A is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. It has an inhibitory effect on tumors. Synonyms: Mitomycin EP Impurity B; Mitiromycin B. Grades: > 95%. CAS No. 4055-39-4. Molecular formula: C16H19N3O6. Mole weight: 349.34. | |
| Mitomycin B | Mitomycin B is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. It has an inhibitory effect on tumors. Synonyms: Mitomycin EP Impurity C; (1aS)-8α-[[(Aminocarbonyl)oxy]methyl]-1,1aα,2,8,8aα,8bα-hexahydro-1,5-dimethyl-8a-hydroxy-6-methoxyazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione;[1aS-(1aalpha,8alpha,8aalpha,8balpha)]-8-[[(Aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione. Grades: > 95%. CAS No. 4055-40-7. Molecular formula: C16H19N3O6. Mole weight: 349.34. | |
| Mitomycin d | Heterocyclic Organic Compound. Alternative Names: (1aS, 8R, 8aR, 8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-hydroxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. CAS No. 10169-34-3. Molecular formula: C15H18N4O5. Mole weight: 334.33. Purity: 0.96. IUPACName: Mitomycin D. Canonical SMILES: CC1=C (C (=O)C2=C (C1=O)N3CC4C (C3 (C2COC (=O)N)O)N4C)N. Density: 1.64g/cm³. Catalog: ACM10169343. |  |
| Mitomycin D | Mitomycin D. Group: Biochemicals. Alternative Names: (1aS, 8R, 8aR, 8bS) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-hydroxy-1, 5-dimethylazirino[2', 3': 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Highly Purified. CAS No. 10169-34-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C15H18N4O5. US Biological Life Sciences. | Worldwide |
| Mitomycin D | Mitomycin D is a mito-mycin antibiotic produced by Streptomyces caespitosus with anti-tumor activity. It is also a semi-synthetic antibiotic with anti-leukemic properties. Uses: An antitumor antibiotic. it is used as antineoplastic. Synonyms: 7-Demethoxy-7-aminomitomycin B; (1aS, 8R, 8aR, 8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-hydroxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; [(1aS, 8S, 8aR, 8bS)-6-Amino-8a-hydroxy-1, 5-dimethyl-4, 7-dioxo-1, 1a, 2, 4, 7, 8, 8a, 8b-octahydroazireno[2', 3':3, 4]pyrrolo[1, 2-a]indol-8-yl]methylcarbamate; Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-amino-8-(((aminocarbonyl)oxy)methyl)-1,5-dimethyl-8a-hydroxy-, (1aS-(1a-α,8-β,8a-α,8b-α))-; BRN 4720574; NSC 123106. Grades: 95%. CAS No. 10169-34-3. Molecular formula: C15H18N4O5. Mole weight: 334.33. | |
| Mitomycin EP Impurity A | Mitomycin EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 621-79-4. Molecular Formula: C9H9NO. Mole Weight: 147.17. Catalog: APB621794. |  |
| Mitomycin EP Impurity B | Mitomycin EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4055-39-4. Molecular Formula: C16H19N3O6. Mole Weight: 349.34. Catalog: APB4055394. | |
| Mitomycin EP Impurity C | Mitomycin EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4055-40-7. Molecular Formula: C16H19N3O6. Mole Weight: 349.34. Catalog: APB4055407. | |
| Mitomycin Impurity 1 | Mitomycin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 99745-88-7. Molecular Formula: C14H16N4O5. Mole Weight: 320.31. Catalog: APB99745887. | |
| Mitomycin Impurity 2 | Mitomycin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 98462-75-0. Molecular Formula: C14H16N4O5. Mole Weight: 320.31. Catalog: APB98462750. | |
| N-7-(2-(Nitrophenyldithio)ethyl)mitomycin C | N-7-(2-(Nitrophenyldithio)ethyl)mitomycin C, an analogue of mitomycin C, is active against a range of tumor cell lines and xenografts, including MMC-resistant tumors. Synonyms: (1aS,8R,8aR,8bS)-8-[[(Aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-6-[[2-[(4-nitrophenyl)dithio]ethyl]amino]-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; [1aS-(1aα, 8β, 8aα, 8bα)]-8-[[(Aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methyl-6-[[2-[(4-nitrophenyl)dithio]ethyl]amino]-azirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; BMY 25067; N-7-(2-Nitrophenyldithio)ethyl)mitomycin C. Grades: ≥95%. CAS No. 95056-36-3. Molecular formula: C23H25N5O7S2. Mole weight: 547.60. | |
| N-FMOC Mitomycin C | N-FMOC Mitomycin C. Group: Biochemicals. Alternative Names: N-FMOC [1aS-(1aα,8 β , 8aα , 8bα ) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| N-FMOC Mitomycin C | N-FMOC Mitomycin C is used to protect Mitomycin C, an anti-tumor antibiotic. Synonyms: N-FMOC [1aS-(1aα, 8β, 8aα, 8bα)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, '3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Molecular formula: C30H28N4O7. Mole weight: 556.56. | |
| N-Methyl Mitomycin A | N-Methyl Mitomycin A. Group: Biochemicals. Alternative Names: (1aS, 8S, 8aR, 8bS) -8-[[ (Aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-6, 8a-dimethoxy-1, 5-dimethylazirino[2', 3': 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; [1aS-(1aα,8 β , 8aα , 8bα ) ]-8-[[ (Aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-6, 8a-dimethoxy-1, 5-dimethylazirino[2', 3': 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; Mitomycin F; N-Methylmitomycin A; 1, 1a, 2, 8, 8a, 8b-Hexahydro-8-(hydroxymethyl)-6, 8aα-dimethoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione Carbamate. Grades: Highly Purified. CAS No. 18209-14-8. Pack Sizes: 2.5mg. Molecular Formula: C17H21N3O6, Molecular Weight: 363.37. US Biological Life Sciences. | Worldwide |
| N-Methyl Mitomycin A | N-Methyl Mitomycin A is an intermediate of Mitocycin B. Mitomycin is a drug which is used for treatment of malignant neoplasm of lip. Synonyms: (1aS, 8S, 8aR, 8bS)-8-[[(Aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-6, 8a-dimethoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; [1aS-(1aα, 8β, 8aα, 8bα)]-8-[[(Aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-6, 8a-dimethoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; Mitomycin F; N-Methylmitomycin A; 1, 1a, 2, 8, 8a, 8b-Hexahydro-8-(hydroxymethyl)-6, 8aα-dimethoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione Carbamate. Grades: ≥95%. CAS No. 18209-14-8. Molecular formula: C17H21N3O6. Mole weight: 363.36. | |
| 1-Hydroxy-2,7-diamino Mitosene (Mixture cis/trans) | 1-Hydroxy-2,7-diamino Mitosene (Mixture cis/trans) is a Mitomycin impurity, Mitomycin is a drug which is used for treatment of malignant neoplasm of lip. Uses: Mitomycin (m371900) impurity. Synonyms: (2S)-2,7-Diamino-9-[[(aminocarbonyl)oxy]methyl]-2,3-dihydro-1-hydroxy-6-methyl-1H-pyrrolo[1,2-a]indole-5,8-dione. Grades: 95%. CAS No. 1192552-64-9. Molecular formula: C14H16N4O5. Mole weight: 320.30. | |
| 4-Chlorobutanoyl Chloride | 4-Chlorobutanoyl Chloride is used to prepare mitosene and mitosane analogues of Mitomycin C, an antitumor antibiotic. Synonyms: 4-Chloro-Butanoyl Chloride; 4-Chlorobutanoic Acid Chloride; 4-Chlorobutanoyl Chloride; 4-Chlorobutyric Acid Chloride; 4-Chlorobutyroyl Chloride; 4-Chlorobutyryl Chloride; γ-Chlorobutyroyl Chloride; γ-Chlorobutyryl Chloride; ω-Chlorobutanoyl Chloride; ω-Chlorobutyryl Chloride. Grades: ≥95%. CAS No. 4635-59-0. Molecular formula: C4H6Cl2O. Mole weight: 141.00. | |
| C527 | C527 is an inhibitor of USP1/UAF complex deubiquitinase activity. It is a high potency for the USP1/UAF1 complex with IC50 of 0.88 μM. C527 increases ubiquinated Fanconi anemia complementation group D2 (FANCD2-Ub) and FANCI-Ub levels in a concentration-dependent manner. It also inhibits homologous recombination repair, cell proliferation, and sensitizes HeLa cells to the DNA crosslinker mitomycin C. Synonyms: C-527; C 527. Grades: ≥98%. CAS No. 192718-06-2. Molecular formula: C17H8FNO3. Mole weight: 293.3. | |
| cis-1-Hydroxy-2,7-diamino Mitosene | cis-1-Hydroxy-2,7-diamino Mitosene is derived from Mitomycin C. Mitomycin is a drug which is used for treatment of malignant neoplasm of lip. Synonyms: (1S,2S)-2,7-Diamino-9-[[(aminocarbonyl)oxy]methyl]-2,3-dihydro-1-hydroxy-6-methyl-1H-pyrrolo[1,2-a]indole-5,8-dione; (1S-cis)-2,7-Diamino-9-[[(aminocarbonyl)oxy]methyl]-2,3-dihydro-1-hydroxy-6-methyl-1H-Pyrrolo[1,2-a]indole-5,8-dione; 1,2-cis-1-Hydroxy-2,7-diamino-mitosene; Mitomycin Impurity 7; Mitomycin Related Compound 2. Grades: ≥95%. CAS No. 98462-75-0. Molecular formula: C14H16N4O5. Mole weight: 320.30. | |
| Embryonic Fibroblasts, P3, Irradiated, Mouse (DR4 MEF) | MEF cells serve as feeder cells that support the growth of undifferentiated mouse or human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). MEF cells are isolated from 13.5-day old mouse embryos and should be used at early passages. Before use as feeder cells, MEF cells must be mitotically inactivated by γ-irradiation or mitomycin-C treatment. Group: Biologicals. Grades: Molecular Biology Grade. Pack Sizes: 5Vials. US Biological Life Sciences. | Worldwide |
| FR-900490 | FR-900490 is a new type of immunoactive substance isolated from Disocia sp. F-11809. It is effective in reversing the damage to bone marrow caused by mitomycin C. Uses: Fr-900490 is effective in reversing the damage to bone marrow caused by mitomycin c. Synonyms: FR 900490; FR900490; BMY 28700; BMY28700; BMY-28700; (2S,3R)-2-[(L-Asparaginyl)amino]-3-[[(S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoic acid. Grades: >98%. CAS No. 105424-59-7. Molecular formula: C14H22N6O6. Mole weight: 370.36. | |
| Gentisuric acid | Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 25351-24-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-W338852. | |
| Hydramycin | Hydramycin is an anti-tumor antibiotic produced by Streptomyces purpurea P950-4. It has activity against Gram-positive bacteria. It inhibits B16-F10, Moser and HCT-116 cells with IC50s (μg/mL) of 0.0009, 0.0046 and 0.0026, respectively, which is 300-600 times that of mitomycin C. It has a broad anti-cancer spectrum and has a moderate effect on P388 leukemia, with a T/C of 145%. Molecular formula: C22H16O8. Mole weight: 408.36. | |
| Mitosene | A derived from Mitomycin, which is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cell. Synonyms: 3H-Pyrrolo[1,?2-a]?indole. Grades: > 95%. CAS No. 247-67-6. Molecular formula: C11H9N. Mole weight: 155.2. | |
| Porfiromycin | Antibiotic substance isolated from a Streptomyces ardus fermentation broth. Antibacterial; antineoplastic. Group: Biochemicals. Alternative Names: (1aS, 8S, 8aR, 8bS) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-1, 5-dimethylazirino[2', 3': 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; ENT 50825; Methyl Mitomycin C; Methylmitomycin; N-Methylmitomycin C; NCI 56410; NSC 56410; Porfiromycine; Regamycin; U 14743. Grades: Highly Purified. CAS No. 801-52-5. Pack Sizes: 1mg, 2mg. US Biological Life Sciences. | Worldwide |
| Porfiromycin | Porfiromycin is a quinone antibiotic produced by Str. ardus NRRL 2817. It has anti-Gram-positive and negative bacteria activity. It can inhibit sarcoma-180, Ehrlich ascites carcinoma, L-1210, H leukemia (solid type). The dose of inhibiting KB cell protein synthesis is 0.5 μg/mL. It is a bioreductive DNA alkylating agent that preferentially kills hypoxic tumor cells relative to other aerobic counterparts. Synonyms: N-Methylmitomycin C; NSC-56410; U-14743; Methylmitomycin; Methyl mitomycin C; Regamycin; Mitiromycin D; Porphyromycin; (1aS, 8S, 8aR, 8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: >98%. CAS No. 801-52-5. Molecular formula: C16H20N4O5. Mole weight: 348.35. | |
| RAD51 Inhibitor, B02 ((E)-3-Benzyl-2-(2-(pyridin-3-yl)vinyl)quinazolin-4(3H)-one) | A cell-permeable pyridinylvinyl-quinazolinone compound that is shown to specifically inhibit human RAD51 (IC50=27.4uM). Does not affect RecA even at much higher concentration (~250uM). Directly interacts with RAD51 (=5.6uM), and disrupts its binding to DNA and nucleoprotein filament formation. Blocks double-strand break-induced homologous recombination and enhances sensitivity of cells to Cisplatin and Mitomycin C. Diminishes co-aggregate formation between RAD51-ssDNA filament and dsDNA. RAD51-Stimulatory Compound-1, RS-1 is also available. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| RAD51 Inhibitor, RI-1 | A cell-permeable 1H-Pyrrole-2,3-dione derivative that covalently binds to RAD51 at Cys319 and irreversibly destabilizes a protein-protein interface that is essential for filament formation and recombinase activity. Stimulates single strand annealing at a 5-30uM concentration. Inhibits subnuclear RAD51 foci formation following DNA damage without affecting replication protein A. Also, effectively sensitizes cancer cells to mitomycin C (~25uM) and generate synergistic cell kill in RAD51C mutant cells and with lesser effect on RAD51 complemented cells. Satisfies all four Lipinski rules for predicting drug likeness.CAS No:415713-60-9. Group: Biochemicals. Alternative Names: 3-chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione. Grades: Highly Purified. CAS No. 415713-60-9. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?N?O?, Molecular Weight: 361.6. US Biological Life Sciences. | Worldwide |
| trans-1-Hydroxy-2,7-diamino Mitosene | Trans-1-Hydroxy-2,7-diamino Mitosene is an impurity of Mitocycin. Mitomycin is a drug which is used for treatment of malignant neoplasm of lip. Synonyms: (1R-trans)-2,7-Diamino-9-[[(aminocarbonyl)oxy]methyl]-2,3-dihydro-1-hydroxy-6-methyl-1H-Pyrrolo[1,2-a]indole-5,8-dione. CAS No. 99745-88-7. Molecular formula: C14H16N4O5. Mole weight: 320.30. | |
| WS1279 | WS1279 is a lipopeptide isolated from the fermentation broth of Streptomyces willmorei No. 1279. It stimulated the proliferation of mouse bone marrow cells in vitro and accelerated the recovery of granulocyte counts in bone marrow from leukopenia induced by mitomycin C (MMC) in mice. Synonyms: WS 1279; WS-1279; S-(2,3-bis(palmitoyloxy)propyl)-N-palmitoyl-L-cysteinyl-L-asparaginyl-L-serylglycylglycyl-L-serine. CAS No. 129712-27-2. Molecular formula: C68H125N7O15S. Mole weight: 1312.8. | |
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