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monoamine oxidase A mitochondrial outer-membrane flavoprotein (FAD) that catalyses the oxidative deamination of neurotransmitters and biogenic amines. Acts on primary amines, and also on some secondary and tertiary amines. It differs from EC 1.4.3.21, primary-amine oxidase as it can oxidize secondary and tertiary amines but not methylamine. This enzyme is inhibited byacetylenic compounds such as chlorgyline, 1-deprenyl and pargyline but, unlike EC 1.4.3.21 and EC 1.4.3.22 (diamine oxidase), it is not inhibited by semicarbazide. Group: Enzymes. Synonyms: adrenalin oxidase; adrenaline oxidase; amine oxidase (ambiguous); amine oxidase (flavin-containing); amine:oxygen ox. Enzyme Commission Number: EC 1.4.3.4. CAS No. 9001-66-5. Monoamine Oxidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1481; monoamine oxidase; EC 1.4.3.4; 9001-66-5; adrenalin oxidase; adrenaline oxidase; amine oxidase (ambiguous); amine oxidase (flavin-containing); amine:oxygen oxidoreductase (deaminating) (flavin-containing); epinephrine oxidase; MAO; MAO A; MAO B; MAO-A; MAO-B; monoamine oxidase A; monoamine oxidase B; monoamine:O2 oxidoreductase (deaminating); polyamine oxidase (ambiguous); serotonin deaminase; spermidine oxidase (ambiguous); spermine oxidase (ambiguous); tyraminase; tyramine oxidase. Cat No: EXWM-1481. Creative Enzymes
Monoamine oxidase Monoamine oxidase. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AMINE:OXYGEN OXIDOREDUCTASE [DEAMINATING];TYRAMINE OXIDASE;amine oxidase, flavin-containing;plasma amine oxidase from bovine plasma;tyramine oxidase from arthrobacter*species;Oxidase, monoamine;YRAMINE OXIDASE FROM ARTHROBACTER &;tyramine oxidase fro. Product Category: Heterocyclic Organic Compound. CAS No. 9001-66-5. Purity: 0.96. Product ID: ACM9001665. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
Monoamine Oxidase A from Human, Recombinant MAO's are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo-and xenobiotic amines. Substrate specificity differs for each isozyme. Monoamine oxidase a contains binding sites for 8α-s-cysteinyl-fad. Applications: Monoamine oxidase a has been used in a study to assess abnormal behavior in a large kindred of males where a deficiency of enzymatic activity of monamine oxidase a was found. it has also been used in a study to investigate an ass ociation between smoking and the inhibition of maoa. Group: Enzymes. Synonyms: MAO-A; MAOA; EC 1.4.3.4; Monoamine Oxidase A; adrenalin oxidase; adrenaline oxidase; amine oxidase (ambiguous); amine oxidase (flavin-containing); amine:oxygen oxidoreducta. Enzyme Commission Number: EC 1.4.3.4. CAS No. 231-791-2. Monoamine Oxidase. Storage: -70°C. Source: Baculovirus infected BTI insect cells. Species: Human. MAO-A; MAOA; EC 1.4.3.4; Monoamine Oxidase A; adrenalin oxidase; adrenaline oxidase; amine oxidase (ambiguous); amine oxidase (flavin-containing); amine:oxygen oxidoreductase (deaminating) (flavin-containing); epinephrine oxidase; monoamine:O2 oxidoreductase (deaminating); polyamine oxidase (ambiguous); serotonin deaminase; spermidine oxidase (ambiguous); spermine oxidase (ambiguous); tyraminase; tyramine oxidase. Cat No: NATE-0440. Creative Enzymes
Monoamine Oxidase B from Human, Recombinant MAO's are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo-and xenobiotic amines. Substrate specificity differs for each isozyme. Monoamine oxidase b is a mit ochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs. Applications: Drugs that inhibit monoamine oxidase b activity are used for the treatment of various neurological disorders including depression. monoamine oxidase b has been used in a study to assess the effect of age in 23 different regions of the human brain. it has also been used in a study to determine the specific l ocations of monoamine oxidase in the human brain. Group: Enzymes. Synonyms: MAO-B; MAOB; EC 1.4.3.4; Monoamine Oxida. Enzyme Commission Number: EC 1.4.3.4. CAS No. 231-791-2. Monoamine Oxidase. Storage: -70°C. Source: Baculovirus infected BTI insect cells. Species: Human. MAO-B; MAOB; EC 1.4.3.4; Monoamine Oxidase B; adrenalin oxidase; adrenaline oxidase; amine oxidase (ambiguous); amine oxidase (flavin-containing); amine:oxygen oxidoreductase (deaminating) (flavin-containing); epinephrine oxidase; monoamine:O2 oxidoreductase (deaminating); polyamine oxidase (ambiguous); serotonin deaminase; spermidine oxidase (ambiguous); spermine oxidase (ambiguous); tyraminase; tyramine oxidase. Cat No: NATE-0441. Creative Enzymes
Monoamine Oxidase (Crude Enzyme) L-Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines. They are found bound to the outer membrane of mitochondria in most cell types in the body. The enzyme was originally discovered by Mary Bernheim in the liver and was named tyramine oxidase. They belong to the protein family of flavin-containing amine oxidoreductases. This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Synthesis; drug development; analysis; medicine. Group: Enzymes. Synonyms: equilase; caperase; optidase; catalase-peroxidase; CAT. Enzyme Commission Number: EC 1.4.3.4. CAS No. 9001-66-5. Monoamine Oxidase. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. equilase; caperase; optidase; catalase-peroxidase; CAT. Pack: 100ml. Cat No: NATE-1808. Creative Enzymes
Monoamine oxidase, plasma Monoamine oxidase (EC 1.4.3.4) is an enzyme composed of different polypeptides. Monoamine oxidation catalyzes the oxidative deamination of various biological amines in brain and peripheral tissues by producing hydrogen peroxide. Monoamine oxidase plays an important role in maintaining the regulation of synaptic transmission, emotional behavior and other brain functions [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9001-66-5. Pack Sizes: 100 U. Product ID: HY-E70074. MedChemExpress MCE
Anti-Monoamine Oxidase B antibody produced in rabbit ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
Anti-Monoamine Oxidase B (C-terminal) antibody produced in rabbit affinity isolated antibody, ~1.5 mg/mL, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
1,4-Naphthoquinone 1,4-Naphthoquinone is a potential pharmacophore for inhibition of both MAO (monoamine oxidase) and DNA topoisomerase activities, this latter associated with antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130-15-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W015490. MedChemExpress MCE
1-(5-Bromo-2-pyridyl)ethanone 1-(5-Bromo-2-pyridyl)ethanone is a reagent used to synthesize substituted pyridin-3-yl) phenyloxazolidinones as antibacterial agents with reduced activity against monoamine oxidase A. Group: Biochemicals. Grades: Highly Purified. CAS No. 214701-49-2. Pack Sizes: 2.5g, 10 g. Molecular Formula: C7H6BrNO, Molecular Weight: 200.03. US Biological Life Sciences. USBiological 9
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(1S,2R)-Tranylcypromine-d5 Hydrochloride (1S,2R)-Tranylcypromine Hydrochloride (T715000) is used in the preparation of piperidine derivatives, which serve as LSD1 inhibitors for the treatment of cancer.(1S,2R)-Tranylcypromine Hydrochloride (T715000) has been shown to increase monoamine oxidase inhibition andinhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C9H6D5N.HCl, Molecular Weight: 138.123646. US Biological Life Sciences. USBiological 9
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(2-Bromoethyl-1,1,2,2-d4)-benzene (2-Bromoethyl-1,1,2,2-d4)-benzene is an intermediate used in the synthesis of Phenelzine-d4 Sulfate (P295902), which is a labeled hydrazine derivative that is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) and also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA levels. It is an antidepressant and anxiolytic used in the treatment of major depressive disorder (MDD) as well as other neural disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 1204688-07-2. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C8H5D4Br, Molecular Weight: 189.09. US Biological Life Sciences. USBiological 10
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(2E)-1-(5-Bromo-2-thienyl)-3-[4-(dimethylamino)phenyl]-2-propen-1-one (2E)-1-(5-Bromo-2-thienyl)-3-[4-(dimethylamino)phenyl]-2-propen-1-one is a monoamine oxidase B (MAO-B) inhibitor. Monoamine oxidase B is involved in the metabolism of dopamine. Mao-B inhibitors are potential compounds used to treat Parkinson's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 948841-07-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H14BrNOS, Molecular Weight: 336.25. US Biological Life Sciences. USBiological 10
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2-Phenylethylamine HCl 2-Phenylethylamine is a natural alkaloid. It functions as a neuromodulator and a neurotransmitter in the central nervous system. It is found in several different strains of fungi and bacteria, such as Lactobacillus and Pseudomonas. 2-Phenylethylamine also possesses anti-microbial effects against strains of E. Coli. 2-Phenylethylamine is a substrate of B monoamine oxidase, and derivatives of 2-Phenylethylamine are metabolites in other parts of the central nervous system. Increased levels of 2-Phenylethylamine are found following aerobic exercise. 2-Phenylethylamine is studied to determine the various roles it plays in the central nervous system and other tissues. As a reagent, it has been used in the construction of anti-depressants, inhibitors of leukotrienes and adenosine derivatives. Group: Biochemicals. Alternative Names: Phenethylammonium chloride; Beta-Phenylethylamine hydrochloride; β-Phenylethylamine hydrochloride. Grades: Highly Purified. CAS No. 156-28-5. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C?H??N HCl, Molecular Weight: 121.18. US Biological Life Sciences. USBiological 8
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2-Propynal 2-Propynal is hypothesized to be a possible metabolite of pargyline, a monoamine oxidase inhibitor that is used as an antihypertensive agent. 2-Propynal is also known to induce hepatocyte toxicity in vivo in rats. Group: Biochemicals. Grades: Highly Purified. CAS No. 624-67-9. Pack Sizes: 100mg, 500mg. Molecular Formula: C3H2O. US Biological Life Sciences. USBiological 10
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(2R) -2- [ [4- [ (3-fluorophenyl) methoxy] phenyl] methylamino] propanamide An impurity of safinamide, which is a selective monoamine oxidase B inhibitor reducing degradation of dopamine. Synonyms: Safinamide Impurity 4; (R)-N2-{4-[(3-fluorobenzyl)oxy]benzyl}alaninamide. Grades: ≥ 98%. CAS No. 174756-44-6. Molecular formula: C17H19FN2O2. Mole weight: 302.349. BOC Sciences 8
3-Butyn-2-ol 3-Butyn-2-ol is an intermediate used to prepare aminoindanes with inhibitory activity toward acetylcholine esterase and monoamine oxidase useful as anti-Alzheimer's agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 2028-63-9. Pack Sizes: 1g, 5g. Molecular Formula: C4H6O, Molecular Weight: 70.09. US Biological Life Sciences. USBiological 10
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3- (Pentylamino) propanenitrile 3- (Pentylamino) propanenitrile is a substrate and time-dependent irreversible inactivator of monoamine oxidase B (MAO B). Group: Biochemicals. Grades: Highly Purified. CAS No. 59676-91-4. Pack Sizes: 500mg, 2.5 g. Molecular Formula: C8H16N2, Molecular Weight: 140.229999999999. US Biological Life Sciences. USBiological 10
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(3R)-2,3-Dihydro-3-(2-propyn-1-ylamino)-1H-inden-1-one A building block in the preparation of Rasagiline.Rasagiline is an irreversible inhibitor of monoamine oxidase-B. It can be used as a monotherapy to treat symptoms in early Parkinson's disease or as an adjunct therapy in more advanced cases. Synonyms: 3-keto-Npropargyl-1-aminoindan. Grades: > 95%. Molecular formula: C12H11NO. Mole weight: 185.23. BOC Sciences 7
4-methylaminobutanoate oxidase (methylamine-forming) The enzyme participates in the nicotine degradation pathway of the soil bacterium Arthrobacter nicotinovorans. Has a very weak monoamine oxidase (EC 1.4.3.4) activity with 4-aminobutanoate. Group: Enzymes. Synonyms: mao (gene name, ambiguous). Enzyme Commission Number: EC 1.5.3.21. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1549; 4-methylaminobutanoate oxidase (methylamine-forming); EC 1.5.3.21; mao (gene name, ambiguous). Cat No: EXWM-1549. Creative Enzymes
4-Phenoxyphthalonitrile 4-Phenoxyphthalonitrile is a C4-substituted phthalonitrile with monoamine oxidase inhibitory activity. 4-Phenoxyphthalonitrile is used in organic pigments and dyes. Group: Biochemicals. Alternative Names: 4-Phenoxy-1,2-benzenedicarbonitrile; 4-Phenoxyphthalonitrile; NSC 646245. Grades: Highly Purified. CAS No. 38791-62-7. Pack Sizes: 1g. US Biological Life Sciences. USBiological 2
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5-[[Methyl(2-propyn-1-yl)amino]methyl]-8-quinolinol Dihydrochloride M 30 dihydrochloride is a potent and brain selective inhibitor of monoamine oxidase (MAO) with EC50 values of 37 and 57 nM for MAO-A and MAO-B, respectively. M 30 decreases cell death rates and apoptotic DNA damage, exhibiting neuroprtective properties. Synonyms: 5-[[methyl(prop-2-ynyl)amino]methyl]-8-quinolinol;dihydrochloride; 5-[[methyl(prop-2-ynyl)amino]methyl]quinolin-8-ol;dihydrochloride. Grades: ≥ 98 % by HPLC. CAS No. 64821-19-8. Molecular formula: C14H16Cl2N2O. Mole weight: 299.20. BOC Sciences 10
Amitraz Amitraz is a non-systemic acaricide and insecticide with alpha-adrenergic agonist activity that interacts with octopamine receptors in the central nervous system and inhibits monoamine oxidase and prostaglandin synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BTS-27419. CAS No. 33089-61-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-B1111. MedChemExpress MCE
Aquayamycin Aquayamycin is a quinone antibiotic produced by Streptomyces misawanensis MA944-A5. Aquayamycin has weak antibacterial activity, prolongs the life of mice inoculated with Ehrlich ascites cancer, and inhibits tyrosine hydroxylase and monoamine oxidase. Synonyms: Urdamycinone A; 9-(2,6-Dideoxy-beta-D-arabino-hexopyranosyl)-3,4,4a,12b-tetrahydro-3,4a,8,12b-tetrahydroxy-3-methylbenz(a)anthracene-1,7,12(2H)-trione (3R-(3alpha,4aalpha,12balpha))-. Grades: >98%. CAS No. 26055-63-0. Molecular formula: C25H26O10. Mole weight: 486.47. BOC Sciences
Benzeneethan-α,α, β, β-d4-ol Benzeneethan-α,α, β, β-d4-ol is an intermediate used in the synthesis of Phenelzine-d4 Sulfate (P595902), which is a labeled hydrazine derivative that is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) and also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA levels. It is an antidepressant and anxiolytic used in the treatment of major depressive disorder (MDD) as well as other neural disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 107473-33-6. Pack Sizes: 5mg, 10mg. Molecular Formula: C8H6D4O, Molecular Weight: 126.19. US Biological Life Sciences. USBiological 2
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Benzylamine hydrochloride Benzylamine hydrochloride is a substrate for benzylamine oxidase and monoamine oxidase B. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Phenylmethylamine. CAS No. 3287-99-8. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-76253. MedChemExpress MCE
Bifemelane hydrochloride Bifemelane hydrochloride (MCI-2016) is a potent, selective and competitive inhibitor of monoamine oxidase A (MAO-A) , with a K i of 4.20 μM. Bifemelane hydrochloride also inhibits MAO-B noncompetitively with a K i of 46.0 μM. Bifemelane hydrochloride has a potent antidepressant activity and can be used for the research of cognitive and emotional disturbances related to cerebrovascular disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCI-2016. CAS No. 62232-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1558A. MedChemExpress MCE
Bizine Lysine-specific demethylase 1 (LSD1) is an epigenetic enzyme, which can oxidatively cleave methyl groups from monomethyl and dimethyl Lys4 of histone H3. Bizine is an LSD1 inhibitor, which is a phenelzine analog that inhibits lysine-specific demethylase 1 with ki of 59 nM. It is 23-fold, 63-fold, and >100-fold selective for LSD-1 over monoamine oxidase (MAO) A, MAOB, and LSD2, respectively. Synonyms: BSM-0353. Grades: ≥95%. CAS No. 1591932-50-1. Molecular formula: C18H23N3O. Mole weight: 297.4. BOC Sciences 9
Brofaromine Brofaromine (CGP 11305A) is a monoamine oxidase ( MAO ) inhibitor with IC 50 of 0.2?μM for MAO-A. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 11305A. CAS No. 63638-91-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13339. MedChemExpress MCE
Brofaromine Hydrochloride Brofaromine Hydrochloride is a reversible inhibitor of monoamine oxidase A(RIMA). It acts on norepinephrine, epinephrine, serotonin and dopamine. It was mainly used in the treatment of depression and anxiety. It was developed by Novartis and was in clinic phase 3, but now it was terminated. Uses: Brofaromine hydrochloride was mainly used in the treatment of depression and anxiety. Synonyms: CGP-11305A HCl;CGP11305A HCl;Brofaromine HCl;4-(7-Bromo-5-methoxy-2-benzofuranyl)piperidine hydrochloride;Piperidine, 4-(7-bromo-5-methoxy-2-benzofuranyl)-, monohydrochloride. Grades: 98%. CAS No. 63638-90-4. Molecular formula: C14H17BrClNO2. Mole weight: 346.65. BOC Sciences 10
CAY10680 The monoamine oxidases A and B are the products of two abutting X-linked genes, and play an important role in the metabolism of biogenic amines in the central nervous system. Inhibition of MAO-B is considered as a strategy to treat Parkinson's disease. CAY10680 is a benzothiazinone compound that selectively inhibits MAO-B with IC50 = 34.9 nM in human. The blockade of adenosine A2A receptors has emerged as a potential treatment for Parkinson's disease. CAY10680 has been shown to abolish cAMP accumulation in CHO cells transfected with adenosine A2A receptors. It can selectively inhibits with Ki of 39.5 nM in human. Synonyms: CAY 10680; CAY-10680. Grades: ≥98%. CAS No. 1439488-21-7. Molecular formula: C18H16N2O2S. Mole weight: 324.4. BOC Sciences 9
Chaetoviridin A (CCRIS 7226) Azaphilone antibiotic. Antifungal compound (phytopathogenic fungi). Cholesteryl ester transfer protein (CETP) inhibitor. Improves blood lipid levels. Monoamine oxidase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 128252-98-2. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. USBiological 4
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Cinnamylamine Hydrochloride Cinnamylamine Hydrochloride, can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 5586-89-0. Pack Sizes: 25mg, 100mg. Molecular Formula: C9H12ClN, Molecular Weight: 169.65. US Biological Life Sciences. USBiological 4
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cis-2-Phenylcyclopropane carbohydrazide cis-2-Phenylcyclopropane carbohydrazide can be used with a series of other derivatives of 2-?phenylcyclopropyl amine and analogs in order to study relationships between chemical structure and monoamine oxidase-?inhibiting activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 17364-52-2. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C10H12N2O, Molecular Weight: 176.22. US Biological Life Sciences. USBiological 5
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Clorgyline hydrochloride Clorgyline is a potent monoamine oxidase (MAO) inhibitor that preferentially targets MAO-A over MAO-B (Kis = 0.054 and 58 μM, respectively). This inhibition is irreversible. Clorgyline is without effect on serotonin receptors, but it does inhibit the sigma receptor σ1 on Jurkat human T lymphocyte cells (IC50 = 31 nM). Synonyms: N-2,4-Dichlorophenoxypropyl-N-methylpropargylamine. Grades: ≥98%. CAS No. 17780-75-5. Molecular formula: C13H15Cl2NO·HCl. Mole weight: 308.6. BOC Sciences 10
Contezolid Contezolid (MRX-I), a new and orally active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid (MRX-I) markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MRX-I. CAS No. 1112968-42-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19915. MedChemExpress MCE
diamine oxidase A group of enzymes that oxidize diamines, such as histamine, and also some primary monoamines but have little or no activity towards secondary and tertiary amines. They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone) and, like EC 1.4.3.21 (primary-amine oxidase) but unlike EC 1.4.3.4 (monoamine oxidase), they are sensitive to inhibition by carbonyl-group reagents, such as semicarbazide. Group: Enzymes. Synonyms: amine oxidase (ambiguous); amine oxidase (copper-containing) (ambiguous); CAO (ambiguous); Cu-containing amine oxidase (ambiguous); copper amine oxidase (ambiguous); diamine oxidase (ambiguous); diamino oxhydrase (ambiguous); histaminase; histamine deaminase (incorrect); semicarbazide-sensitive amine oxidase (incorrect); SSAO (incorrect). Enzyme Commission Number: EC 1.4.3.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1477; diamine oxidase; EC 1.4.3.22; amine oxidase (ambiguous); amine oxidase (copper-containing) (ambiguous); CAO (ambiguous); Cu-containing amine oxidase (ambiguous); copper amine oxidase (ambiguous); diamine oxidase (ambiguous); diamino oxhydrase (ambiguous); histaminase; histamine deaminase (incorrect); semicarbazide-sensitive amine oxidase (incorrect); SSAO (incorrect). Cat No: EXWM-1477. Creative Enzymes
(E)-2-Thiopheneacrylic Acid (E)-2-Thiopheneacrylic Acid is used in the synthesis of anti-HIV HEPT analogs. Also used in the synthesis of benzimidazole and caffeine (C080100) analogs as inhibitors of monoamine oxidase B. Group: Biochemicals. Alternative Names: (E)-3-(Thiophen-2-yl)-2-propenoic Acid; (E)-3-(Thiophen-2-yl)acrylic Acid; trans-3-Thiopheneacrylic Acid; (E)-2-Thiopheneacrylic Acid; (E)-3-(2-Thienyl)-2-propenoic Acid. Grades: Highly Purified. CAS No. 15690-25-2. Pack Sizes: 10g. US Biological Life Sciences. USBiological 3
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(E)-N-Methylcinnamylamine (E)-N-Methylcinnamylamine is an 3-amino-1-phenyl-prop-1-ene derivative with potential to inhibit and inactivate monoamine oxidase. Group: Biochemicals. Alternative Names: (2E)-N-Methyl-3-phenyl-2-propen-1-amine; (E)-N-Methyl-3-phenyl-2-propen-1-amine. Grades: Highly Purified. CAS No. 116939-14-1. Pack Sizes: 1g. US Biological Life Sciences. USBiological 2
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Eprobemide Eprobemide is a reversible monoamine oxidase A (MAO-A) inhibitor and can be used as an antidepressant. Synonyms: LIS 630. Grades: 98%. CAS No. 87940-60-1. Molecular formula: C14H19ClN2O2. Mole weight: 282.769. BOC Sciences 10
Escitalopram Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase. Uses: Serotonin uptake inhibitors; antidepressive agents, second-generation. Synonyms: (S)-Citalopram; S-(+)-Citalopram; Seroplex. Grades: >98%. CAS No. 128196-01-0. Molecular formula: C20H21FN2O. Mole weight: 324.39. BOC Sciences 8
Furazolidone Furazolidone is a monoamine oxidase (MAO) inhibitor with antiproliferative, apoptosis-inducing and differentiation-promoting activities. Furazolidone may inhibit leukemia fusion protein-mediated bone marrow transformation by upregulating the stability of the tumor suppressor protein p53. Furazolidone exhibits anti-leukemic activity in acute myeloid leukemia (AML) cell lines and can be used for anti-AML research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67-45-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1336. MedChemExpress MCE
Harmol Harmol is a TFEB activator, an orally active monoamine oxidase inhibitor that has anti-tumor, anti-depressant, and anti-aging effects. Harmol can induce cell mitosis, autophagy and apoptosis. Harmol promotes the degradation of α-synuclein through the regulation of the autophagy-lysosomal pathway, improving motor deficits in mouse models of Parkinson's disease [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 487-03-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107811. MedChemExpress MCE
Homoveratric Acid Homoveratric Acid is a dopamine metabolite that inhibits brain mitochondrial respiration via monoamine oxidase/H2O2-dependent or non-dependent pathway. Group: Biochemicals. Alternative Names: 3,4-Dimethoxyphenylacetic Acid; 2- (3, 4-Dimethoxyphenyl) acetate; 2-(3,4-Dimethoxyphenyl)acetic Acid; 3,4-Dimethoxybenzeneacetic Acid; NSC 2753; NSC 27897. Grades: Highly Purified. CAS No. 93-40-3. Pack Sizes: 2.5g. US Biological Life Sciences. USBiological 2
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Hydroxylamine hydrochloride Hydroxylamine hydrochloride is a selective monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of organic synthesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5470-11-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-Y0882. MedChemExpress MCE
Iproniazid Iproniazid is a hydrazine based drug used as an antidepressant. Iproniazid acts as an irreversible and nonselective monoamine oxidase inhibitor. Group: Biochemicals. Alternative Names: 4-Pyridinecarboxylic Acid 2-(1-Methylethyl)hydrazide; Isonicotinic Acid 2-Isopropylhydrazide; 1-Isonicotinoyl-2-isopropylhydrazine; Euphozid; IPN; Iprazid; Iprazide; Iproniazide; Isonicotinic Acid N'-Isopropyl Hydrazide; Marsalid; Marsilid; N'-Isopropyl isonicotinoylhydrazide . Grades: Highly Purified. CAS No. 54-92-2. Pack Sizes: 500mg. US Biological Life Sciences. USBiological 2
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Iproniazid Iproniazid is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid has antidepressive activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54-92-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0886A. MedChemExpress MCE
Iproniazid-1-oxide a metabolite of the monoamine oxidase inhibitor, Iproniazid. Synonyms: 4-Pyridinecarboxylic Acid 2-(1-Methylethyl)hydrazide 1-Oxide. Grades: > 95%. CAS No. 36781-38-1. Molecular formula: C9H13N3O2. Mole weight: 195.22. BOC Sciences 6
Iproniazid phosphate Iproniazid phosphate is a non-selective, irreversible inhibitor of monoamine oxidase (MAOI) that has potential to treat hypertension. Synonyms: phosphoric acid;N'-propan-2-ylpyridine-4-carbohydrazide Iproniazid phosphate 305-33-9 Iproniazide phosphate Marsilid phosphate Isoproniazid phosphate Iproniazid as phosphate N'-Isopropylisonicotinohydrazide phosphate Iproniazid dihydrogen phosphate Iproni. CAS No. 305-33-9. Molecular formula: C9H16N3O5P. Mole weight: 277.21. BOC Sciences 10
Iproniazid phosphate Iproniazid phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid phosphate has antidepressive activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 305-33-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0886. MedChemExpress MCE
Isatin Isatin (Indoline-2,3-dione) is a potent inhibitor of monoamine oxidase (MAO) with an IC 50 of 3 μM. Also binds to central benzodiazepine receptors (IC 50 against clonazepam, 123 μM) [1]. Also acts as an antagonist of both atrial natriuretic peptide stimulated and nitric oxide-stimulated guanylate cyclase activity [2]. Shows effect on the serotonergic system [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Indoline-2,3-dione. CAS No. 91-56-5. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y0265. MedChemExpress MCE
Isocarboxazid Isocarboxazid is a non-selective and irreversible inhibitor of monoamine oxidase , with an IC 50 of 4.8 μM for rat brain monoamine oxidase in vitro [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59-63-2. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-13929. MedChemExpress MCE
Isocarboxazid Isocarboxazid is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) belonging to the hydrazine class. It is primarily used to treat mood and anxiety disorders. It is also used for the treatment of Parkinson's disease and other dementia-related disorders. It is also effective in the treatment of major depression, dysthymic disorder, and atypical depression. It blocks the breakdown (oxidative deamination) of biogenic amines by inhibiting MAO, thereby increasing the concentrations of norepinephrine and 5-hydroxytrytamine at central aminergic receptors. It was developed by Validus and has been listed. Uses: Isocarboxazid is primarily used to treat mood and anxiety disorders. it is also used for the treatment of parkinson's disease and other dementia-related disorders. it is also effective in the treatment of major depression, dysthymic disorder, and atypical. Synonyms: 1-Benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine;3-Isoxazolecarboxylic acid, 5-methyl-, 2-(phenylmethyl)hydrazide;3-Isoxazolecarboxylic acid, 5-methyl-, 2-benzylhydrazide;5-Methyl-3-isoxazole-carboxylic Acid 2-Benzylhydrazide;3-(N-Benzylhydrazinocarbon. Grades: 95%. CAS No. 59-63-2. Molecular formula: C12H13N3O2. Mole weight: 231.25. BOC Sciences 10
Isocarboxazid (5-Methyl-3-isoxazole-carboxylic Acid 2-Benzylhydrazide, 3- (N-Benzyl hydrazinocarbonyl) -5- methyl isoxazole, Ro-5-0831, Marplan) Monoamine oxidase inhibitor. Antidepressant. Group: Biochemicals. Alternative Names: 5-Methyl-3-isoxazole-carboxylic Acid 2-Benzylhydrazide; 3- (N-Benzyl hydrazinocarbonyl) -5- methyl isoxazole; Ro-5-0831; Marplan. Grades: Highly Purified. CAS No. 59-63-2. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 1
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Isopropylhydrazine Hydrochloride Potent monoamine oxidase inhibitor. Group: Biochemicals. Alternative Names: (1-Methylethyl)hydrazine Monohydrochloride. Grades: Highly Purified. CAS No. 16726-41-3. Pack Sizes: 1g. US Biological Life Sciences. USBiological 2
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J147 J147 is an exceptionally potent, orally active, neuroprotective agent for cognitive enhancement. J147 can pass the blood brain barrier (BBB). J147 can inhibit monoamine oxidase B ( MAO B ) and the dopamine transporter. J147 plays an impotant role in Alzheimers disease (AD) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1807913-16-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-13779A. MedChemExpress MCE
Ladostigil Ladostigil, also called as TV-3,326, is a novel neuroprotective agent developed to treat neurodegenerative disorders sunch as Alzheimer's disease. Ladostigil is a dual acetylcholine-butyrylcholineesterase and brain selective monoamine oxidase (MAO)-A and -B inhibitor in vivo (with little or no MAO inhibitory effect in the liver and small intestine). Synonyms: [(3R)-3-(prop-2-ynylamino)-2,3-dihydro-1H-inden-5-yl] N-ethyl-N-methylcarbamate; (N-propargyl-(3R) aminoindan-5-yl)-ethyl methyl carbamate; Ladostigil; TV 3326; TV3326; TV-3326. Grades: >98%. CAS No. 209394-27-4. Molecular formula: C16H20N2O2. Mole weight: 272.348. BOC Sciences 10
Ladostigil hydrochloride Ladostigil (TV-3326) hydrochloride is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO) , with IC 50 s of 37.1 and 31.8 μM for MAO-B and AChE , respectively. Ladostigil hydrochloride exhibits neuroprotective, antioxidant and anti-inflammatory activities. Ladostigil can be used for the research of depression and Alzheimer's disease [1] [2]. Ladostigil (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TV-3326 hydrochloride. CAS No. 209394-18-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10399A. MedChemExpress MCE
Ladostigil tartrate Ladostigil, also called as TV-3,326, is a novel neuroprotective agent developed to treat neurodegenerative disorders sunch as Alzheimer's disease. Ladostigil is a dual acetylcholine-butyrylcholineesterase and brain selective monoamine oxidase (MAO)-A and -B inhibitor in vivo (with little or no MAO inhibitory effect in the liver and small intestine). Uses: A novel brain-selective mao inhibitor, ladostigil can selectively reverse the behavioral and neurochemical effects induced by prenatal stress without affecting the behavior of controls. antidepressant. Synonyms: ethylmethyl-carbamic acid (3r)-2,3-dihydro-3-(2-propynylamino)-1h-inden-5-yl ester (2r,3r)-2,3-dihydroxybutanedioate (2:1); ladostigil tartrate; Ethylmethyl-carbamic acid (3R)-2,3-dihydro-3-(2-propynylamino)-1H-inden-5-yl ester (2R,3R)-2,3-dihydroxybutaned. Grades: >98%. CAS No. 209394-46-7. Molecular formula: 2(C16H20N2O2).C4H6O6. Mole weight: 694.78. BOC Sciences 10
Lazabemide hydrate Lazabemide, a pyridine derivative, is a reversible and selective monoamine oxidase B inhibitor that has probable effect for Parkinson's disease. IC50: 30 nM. It could also influence the absorption of some monoamines like noradrenalin, serotonin and dopami. Uses: Lazabemide is a reversible and selective monoamine oxidase b inhibitor that has probable effect against parkinson's disease. Synonyms: Lazabemide; Cardaptive; MK-0524; MK 0524; MK0524; Laropiprant; N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrate, Ro 19-6327 hydrate. Grades: 95%. CAS No. 103878-84-8. Molecular formula: C8H10ClN3O. Mole weight: 199.64 (anhydrous basis). BOC Sciences 10
Lazabemide hydrochloride Lazabemide is a monoamine oxidase B inhibitor with IC50 values of 0.03 and > 100 μM for MAO-B and MAO-A. It is potentially an antiparkinsonian agent. Uses: Antiparkinson agents. Synonyms: N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 103878-83-7. Molecular formula: C8H10ClN3O.HCl. Mole weight: 236.1. BOC Sciences 9
MAO-IN-1 An inhibitor of monoamine oxidase B (MAO B) (IC50= 20 nM). Synonyms: (2S)-1-[4-[(3-chlorophenyl)methoxy]phenoxy]-3-methoxypropan-2-ol. CAS No. 124991-40-8. Molecular formula: C17H19ClO4. Mole weight: 322.78. BOC Sciences 9
Methamphetamine (BSA) Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 9
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Methamphetamine-S (HRP) Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase. Group: Biochemicals. Grades: Purified. Pack Sizes: 1ml. US Biological Life Sciences. USBiological 4
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Methyl citrate Methyl citrate is a Monoamine oxidase B ( MAO-B ) inhibitor ( IC 50 =0.23 mM). Methyl citrate is isolated from the fruits of Opuntia ficus-indica var. saboten Makino [1]. Uses: Scientific research. Group: Natural products. CAS No. 26163-61-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N9540. MedChemExpress MCE
Methylene Blue Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC) , monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue is a Tau aggregation inhibitor. Methylene blue reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Basic Blue 9; CI-52015; Methylthioninium chloride. CAS No. 61-73-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-14536. MedChemExpress MCE
Methylene blue hydrate Methylene blue (Basic Blue 9) hydrate is a guanylyl cyclase (sGC) , monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue hydrate through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue hydrate is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue hydrate is a Tau aggregation inhibitor. Methylene blue hydrate reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Basic Blue 9 hydrate; CI-52015 hydrate; Methylthioninium chloride hydrate. CAS No. 122965-43-9. Pack Sizes: 1 g; 5 g. Product ID: HY-D0958. MedChemExpress MCE
Methylene blue hydrate Methylene blue (Basic Blue 9) hydrate is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue hydrate through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue hydrate is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue hydrate is a Tau aggregation inhibitor. Methylene blue hydrate reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 122965-43-9. Molecular formula: C16H18ClN3S.xH2O. Mole weight: 337.87. Canonical SMILES: CN(C1=CC2=[S+]C3=C(C=CC(N(C)C)=C3)N=C2C=C1)C.[x].[Cl-].O. Product ID: ACM122965439. Alfa Chemistry — ISO 9001:2015 Certified. Categories: [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;hydrate. Alfa Chemistry.
Methylene blue trihydrate Methylene blue trihydrate (C.I. Basic Blue 9 trihydrate) is a guanylyl cyclase (sGC) , monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue trihydrate is a vasopressor and is often used as a dye in several medical procedures. Methylene blue trihydrate has antinociception, antimalarial, antidepressant and anxiolytic activity effects. Methylene Blue trihydrate has the potential for methemoglobinemias, neurodegenerative disorders and ifosfamide-induced encephalopathytreatment [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C.I. Basic Blue 9 trihydrate. CAS No. 7220-79-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1359. MedChemExpress MCE
Methylene blue trihydrate Methylene blue trihydrate (C.I. Basic Blue 9 trihydrate) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue trihydrate is a vasopressor and is often used as a dye in several medical procedures. Methylene blue trihydrate has antinociception, antimalarial, antidepressant and anxiolytic activity effects. Methylene Blue trihydrate has the potential for methemoglobinemias, neurodegenerative disorders and ifosfamide-induced encephalopathytreatment. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 7220-79-3. Molecular formula: C16H18ClN3S?3(H2O). Mole weight: 373.9. Purity: ≥98.0%. Product ID: ACM7220793. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.

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