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| Product | Description | |
|---|---|---|
| Mucin | porcine Type II. CAS No. 84082-64-4. Product ID: 2-08227. Purity: ~1% bound sialic acid. Reference: toxic solid, light and air sensitive, refrigerate. |  |
| Mucin-1 (950-958) | Mucin-1 (950-958) is a fragment of Mucin-1. The main function of MUC1 is to protect cells from infection by binding to the pathogens with oligosaccharides in the extracellular domain, which prevents the pathogens from reaching the cell surface. It is associated with multiple myeloma. Synonyms: Breast carcinoma-associated antigen DF3 (950-958); Cancer antigen 15-3 (950-958); Carcinoma-associated mucin (950-958). |  |
| Mucin-1 precursor (12-20) | Mucin-1 precursor (12-20) is a fragment of Mucin-1 precursor. The main function of MUC1 is to protect cells from infection by binding to the pathogens with oligosaccharides in the extracellular domain, which prevents the pathogens from reaching the cell surface. It is associated with multiple myeloma. Synonyms: Breast carcinoma-associated antigen DF3 (12-20); Cancer antigen 15-3 (12-20); Carcinoma-associated mucin (12-20). | |
| Mucin-1 (repeated region) | Mucin-1 (repeated region) is a fragment of Mucin-1. The main function of MUC1 is to protect cells from infection by binding to the pathogens with oligosaccharides in the extracellular domain, which prevents the pathogens from reaching the cell surface. It is associated with multiple myeloma. Synonyms: Breast carcinoma-associated antigen DF3 (repeated region); Cancer antigen 15-3 (repeated region); Carcinoma-associated mucin (repeated region). | |
| Mucin-5AC (716-724) | Mucin-5AC (716-724) is a 9-aa peptide. Mucin-5AC is a gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Synonyms: MUC-5AC (716-724); Gastric mucin (716-724); Major airway glycoprotein (716-724). | |
| Mucin from bovine submaxillary glands | Type I-S. Group: Fluorescence/luminescence spectroscopy. |  |
| Gastric mucin | Gastric mucin is a large glycoprotein that is thought to play an important role in protecting the gastrointestinal tract from acids, proteases, pathogenic microorganisms and mechanical damage. Synonyms: Gastron; Mucin type I; ucin type II; ucin type III; ucin type I-S; Gastric Mucin porcine. Grades: ≥97%. CAS No. 84082-64-4. | |
| Gastric mucin | Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 84082-64-4. Pack Sizes: 500 mg; 10 g. Product ID: HY-B2196. |  |
| Gastric Mucin | Gastric Mucin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: mucin from porcine stomach. Appearance: Off White to Light Brown Powder. CAS No. 84082-64-4. Purity: 0.99. Product ID: ACM84082644. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Gastric Mucin powder | Gastric Mucin powder. |  CA, FL & NJ |
| Microbial DNA standard from Akkermansia muciniphila | Suitable for PCR, sequencing and NGS, 10 ng/?L. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-Mucin Gastric antibody produced in mouse | clone 45M1, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| MUC1, mucin core | MUC1, mucin core is the region of the MUC1 mucin core. MUC1 is a type I transmembrane glycoprotein, and is overexpressed and aberrantly glycosylated in carcinoma cells. MUC1, mucin core protein binds to domain 1 of ICAM-1 [1]. Uses: Scientific research. Group: Peptides. CAS No. 149205-73-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2508. | |
| Submandibular mucin | Submandibular mucin is a high molecular weight glycoprotein that is used as a substrate for the viral enzyme neuraminidase [1]. Uses: Scientific research. Group: Peptides. CAS No. 84195-52-8. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-P3008. | |
| 1-Naphthyl Phosphate | 1-Naphthyl Phosphate functions as a substrate in the optimized bioassay for mucin 1 detection in serum samples, and in the analysis and detection of lysozymes in real samples. It also functions as a substrate in the development of automated flow-based electrochemical aptasensor for online detection of ochratoxin A. Group: Biochemicals. Grades: Highly Purified. CAS No. 1136-89-6. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H9O4P, Molecular Weight: 224.15. US Biological Life Sciences. |  Worldwide |
| 4-DAMP | 4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-DAMP methiodide. CAS No. 1952-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100958. | |
| acetylgalactosaminyl-O-glycosyl-glycoprotein β-1,3-N-acetylglucosaminyltransferase | The product of the enzyme is known as core 3, one of the eight core structures of mucin-type O-glycans. O-Linked glycans are polysaccharides or oligosaccharides that are linked to a protein via the oxygen atom in the side chain of an L-serine or L-threonine residue. Group: Enzymes. Synonyms: O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III; uridine diphosphoacetylglucosamine-mucin β(1?3)-acetylglucosaminyltransferase; mucin core 3 &be. Enzyme Commission Number: EC 2.4.1.147. CAS No. 87927-96-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2373; acetylgalactosaminyl-O-glycosyl-glycoprotein β-1,3-N-acetylglucosaminyltransferase; EC 2.4.1.147; 87927-96-6; O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III; uridine diphosphoacetylglucosamine-mucin β(1?3)-acetylglucosaminyltransferase; mucin core 3 β3-GlcNAc-transferase; Core 3β-GlcNAc-transferase; UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R) β-1,3-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-D-glucosamine:N-acetyl-β-D-galactosaminyl-R 3-β-N-acetyl-D-glucosaminyltransferase (incorrect). Cat No: EXWM-2373. |  |
| acetylgalactosaminyl-O-glycosyl-glycoprotein β-1,6-N-acetylglucosaminyltransferase | cf. EC 2.4.1.102 (β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,6-N-acetylglucosaminyltransferase), EC 2.4.1.146 (β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,3-N-acetylglucosaminyltransferase) and EC 2.4.1.147 (acetylgalactosaminyl-O-glycosyl-glycoprotein β-1,3-N-acetylglucosaminyltransferase). Group: Enzymes. Synonyms: O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV; uridine diphosphoacetylglucosamine-mucin β(1?6)-acetylglucosaminyltransferase B; core 4 β. Enzyme Commission Number: EC 2.4.1.148. CAS No. 95978-15-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2374; acetylgalactosaminyl-O-glycosyl-glycoprotein β-1,6-N-acetylglucosaminyltransferase; EC 2.4.1.148; 95978-15-7; O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV; uridine diphosphoacetylglucosamine-mucin β(1?6)-acetylglucosaminyltransferase B; core 4 β6-GalNAc-transferase; core 6β-GalNAc-transferase B; UDP-N-acetyl-D-glucosamine:O-oligosaccharide-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of N-acetyl-β-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R) β-1,6-N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2374. | |
| β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,3-N-acetylglucosaminyltransferase | cf. EC 2.4.1.102 (β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,6-N-acetylglucosaminyltransferase), EC 2.4.1.147 (acetylgalactosaminyl-O-glycosyl-glycoprotein β-1,3-N-acetylglucosaminyltransferase) and EC 2.4.1.148 (acetylgalactosaminyl-O-glycosyl-glycoprotein β-1,6-N-acetylglucosaminyltransferase). Group: Enzymes. Synonyms: O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II; uridine diphosphoacetylglucosamine-mucin β(1?3)-acetylglucosaminyltransferase (elongating); elongation 3&be. Enzyme Commission Number: EC 2.4.1.146. CAS No. 87927-99-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2372; β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,3-N-acetylglucosaminyltransferase; EC 2.4.1.146; 87927-99-9; O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II; uridine diphosphoacetylglucosamine-mucin β(1?3)-acetylglucosaminyltransferase (elongating); elongation 3β-GalNAc-transferase; UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to β-D-galactose of β-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R) β-1,3-N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2372. | |
| β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,6-N-acetylglucosaminyltransferase | The enzyme is involved in O-glycosylation of several proteins, such as mucins. Group: Enzymes. Synonyms: O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; β6-N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-mucin β-(1?6)-acetylglucosaminyltransferase; core 2 acetylglucosaminyltransferase; core 6-β-GlcNAc-transferase A; UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of β-D-. Enzyme Commission Number: EC 2.4.1.102. CAS No. 95978-15-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2330; β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,6-N-acetylglucosaminyltransferase; EC 2.4.1.102; 95978-15-7; O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; β6-N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-mucin β-(1?6)-acetylglucosaminyltransferase; core 2 acetylglucosaminyltransferase; core 6-β-GlcNAc-transferase A; UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of β-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R) β-1,6-N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2330. | |
| β-D-N-Acetylgalactosaminyl 1-3 galactose | β-D-N-Acetylgalactosaminyl 1-3 galactose, the crucial element in the biosynthesis of mucin-type O-glycans, offers pivotal aid in exploring the binding specificity of bacterial toxins and other carbohydrate-binding proteins. As if this isn't compelling enough, the compound also serves in the remedy of multiple sclerosis and other autoimmune diseases. Infused with infinite scientific potential, this product may just be the game-changer in your research endeavors. Synonyms: GalNAcβ1-3Gal; β-D-GalNAc-(1->3)-D-Gal; 3-O-(2-Acetamido-2-desoxy-β-D-galactopyranosyl)-D-galactopyranose; D-Galactopyranose, 3-O-[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]-; 2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->3)-D-galactopyranose; β-D-N-acetylgalactosaminyl-(1->3)-D-galactose. Grades: ≥95%. Molecular formula: C14H25NO11. Mole weight: 383.35. | |
| CaCC Blocker IV, Benzbromarone (CaCC Blocker IV, Calcium-Activated Chloride Channel Blocker IV, TMEM16 Blocker IV, (3,5-dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)methanone, ANO Blocker IV, Anoctamin Blocker IV, BBR) | A cell-permeable uricosuric agent that, in addition to its known efficacy in gout treatment, acts as a reversible CaCC blocker and is reported to be more potent than NFA and NPPB in suppressing 500nM Ionomycin- induced I- influx in TMEM16A-expressing HEK293 cells (IC50 = 9.97, 140, and 150uM, respectively) as well as in blocking voltage-gated Cl- current in TMEM16B-expressing HEK293 cells, while exhibiting much reduced potency against ENaC (alpha, beta, and gamma) or CFTR. Shown to significantly reduce mucin secretion from NHBE (normal human bronchial epithelial) and suppress human ASM (airway smooth muscle) contraction upon muscarinic receptor stimulation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. Molecular Formula: C??H??Br?O?. US Biological Life Sciences. | Worldwide |
| Carboxymethylcellulose Sodium | Carboxymethylcellulose sodium occurs as a white to almost white, odorless, tasteless, granular powder. It is hygroscopic after drying. Synonyms: Akucell; Aqualon CMC; Aquasorb; Blanose; Carbose D; carmellosum natricum; Cel-O-Brandt; cellulose gum; Cethylose; CMC sodium; E466; Finnfix; Glykocellan; Nymcel ZSB; SCMC; sodium carboxymethylcellulose; sodium cellulose glycolate; Sunrose; Tylose CB; Tylose MGA; Walocel C; Xylo-Mucine. CAS No. 9004-32-4. Product ID: PE-0309. Mole weight: 90000~700000. Category: Coating Agents; Stabilizing Agents; Suspending Agents; Tablet and Capsule Disintegrant; Tablet Binder; Viscosity-increasing Agents; water-absorbing Agents. Product Keywords: Binder Excipients; Stabilizers; Suspending Agents; Excipients for Mucosal Drug Delivery Systems Materials; PE-0309; Carboxymethylcellulose Sodium; Coating Agents; Stabilizing Agents; Suspending Agents; Tablet and Capsule Disintegrant; Tablet Binder; Viscosity-increasing Agents; water-absorbing Agents; ; 9004-32-4. UNII: NA. Chemical Name: Cellulose, carboxymethyl ether, sodium salt. Grade: Pharmceutical Excipients. Administration route: Oral, subcutaneous, intramuscular, intraarticular, intrasynovial. Dosage Form: Dental preparations; intraarticular, intrabursal, intradermal, intralesional, and intrasynovial injections; oral drops, solutions, suspensions, syrups and tablets; topical preparations. Stability and Storage Conditions: C |  |
| Clivatuzumab | Clivatuzumab is a humanized anti- mucin monoclonal antibody targeting an epitope in the MUC1 antigen expressed in most pancreatic cancers [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1622075-09-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99968. | |
| Diquafosol tetrasodium | Diquafosol tetrasodium is a P2Y2 receptor agonist that stimulates fluid and mucin secretion on the ocular surface, as a topical treatment of dry eye disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INS365. CAS No. 211427-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0606. | |
| endo-α-N-acetylgalactosaminidase | The enzyme catalyses the liberation of Gal-(1?3)-β-GalNAc α-linked to serine or threonine residues of mucin-type glycoproteins. EngBF from the bacterium Bifidobacterium longum specifically acts on core 1-type O-glycan to release the disaccharide Gal-(1?3)-β-GalNAc. The enzymes from the bacteria Clostridium perfringens, Enterococcus faecalis, Propionibacterium acnes and Alcaligenes faecalis show broader specificity (e.g. they can also release the core 2 trisaccharide Gal-(1?3)-β-(GlcNAc-(1?6)-β)-GalNAc or the core 3 disaccharide GlcNAc-(1?3)-β-GalNAc). The enzyme may play an important role in the degradation and utilization of mucins having co...alactosaminohydrolase. Enzyme Commission Number: EC 3.2.1.97. CAS No. 59793-96-3. O-Glycosidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3960; endo-α-N-acetylgalactosaminidase; EC 3.2.1.97; 59793-96-3; endo-α-acetylgalactosaminidase; endo-α-N-acetyl-D-galactosaminidase; mucinaminylserine mucinaminidase; D-galactosyl-3-(N-acetyl-α-D-galactosaminyl)-L-serine mucinaminohydrolase; endo-α-GalNAc-ase; glycopeptide α-N-acetylgalactosaminidase; D-galactosyl-N-acetyl-α-D-galactosamine D-galactosyl-N-acetyl-galactosaminohydrolase. Cat No: EXWM-3960. | |
| Fudosteine | Fudosteine is a cysteine derivative and a mucoactive agent. Fudosteine inhibits MUC5AC mucin hypersecretion by reducing MUC5AC gene expression [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13189-98-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0393. | |
| Gatipotuzumab | Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 ( TA-MUC1 ). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PankoMab. CAS No. 1264737-26-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99634. | |
| glycoprotein-N-acetylgalactosamine 3-β-galactosyltransferase | The non-reducing O-serine-linked N-acetylgalactosamine residues in mucin glycoproteins can act as acceptors. Group: Enzymes. Synonyms: uridine diphosphogalactose-mucin β-(1?3)-galactosyltransferase; UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-β-D-galactosyltransferase. Enzyme Commission Number: EC 2.4.1.122. CAS No. 97089-61-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2348; glycoprotein-N-acetylgalactosamine 3-β-galactosyltransferase; EC 2.4.1.122; 97089-61-7; uridine diphosphogalactose-mucin β-(1?3)-galactosyltransferase; UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-β-D-galactosyltransferase. Cat No: EXWM-2348. | |
| glycoprotein N-palmitoyltransferase | Acts on mucins. Activated by 1,4-dithiothreitol. Group: Enzymes. Synonyms: mucus glycoprotein fatty acyltransferase. Enzyme Commission Number: EC 2.3.1.96. CAS No. 97162-74-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2278; glycoprotein N-palmitoyltransferase; EC 2.3.1.96; 97162-74-8; mucus glycoprotein fatty acyltransferase. Cat No: EXWM-2278. | |
| Gyki 13324 | GYKI-13324 is bifunctional nitrosoureido derivative and alkylating agent. It can produce long-term or total regression of adenomatous, but only marginal growth delay of mucinous tumors. GYKI-13324, seems to be a candidate in the clinical management of colorectal tumors. Uses: Colorectal tumor. Synonyms: GYKI-13324; GYKI 13324; GYKI13324. N- (2-Chloroethyl) -N'- (4- ( ( ( (2-chloroethyl) amino) carbonyl) nitrosamino) -2, 3-dihydroxybutyl) -N-nitrosourea. Grades: 98%. CAS No. 76123-41-6. Molecular formula: C10H18Cl2N6O6. Mole weight: 389.19. | |
| hyaluronate lyase | The enzyme catalyses the degradation of hyaluronan by a β-elimination reaction. Also acts on chondroitin. The product is more systematically known as 3-(4-deoxy-α-L-threo-hex-4-enopyranosyluronic acid)-2-acetamido-2-deoxy-D-glucose. Group: Enzymes. Synonyms: hyaluronidase (ambiguous); glucuronoglycosaminoglycan lyase (ambiguous); spreading factor; mucinase (ambiguous). Enzyme Commission Number: EC 4.2.2.1. CAS No. 37259-53-3. Hyaluronate Lyase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5084; hyaluronate lyase; EC 4.2.2.1; 37259-53-3; hyaluronidase (ambiguous); glucuronoglycosaminoglycan lyase (ambiguous); spreading factor; mucinase (ambiguous). Cat No: EXWM-5084. | |
| Hyaluronate lyase from Streptococcus equi, Recombinant | Hyaluronate lyase degrades hyaluronate using an elimination reaction to break glycosidic linkages yielding unsaturated disaccharide products. Group: Enzymes. Synonyms: hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase. Enzyme Commission Number: EC 4.2.2.1. CAS No. 37259-53-3. Purity: > 95 % as judged by SDS-PAGE. Hyaluronate Lyase. Mole weight: 38447.1 Da. Activity: 4.6 U/mg. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Streptococcus equi 4047. hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase. Cat No: NATE-1210. | |
| Hyaluronate Lyase from Streptococcus pyogenes, Recombinant | Hyaluronate lyase degrades hyaluronate using an elimination reaction to break glycosidic linkages yielding unsaturated disaccharide products. It is important for the diffusion of toxins and proteins produced by S. pyogenes. Group: Enzymes. Synonyms: hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase. Enzyme Commission Number: EC 4.2.2.1. CAS No. 37259-53-3. Hyaluronate Lyase. Activity: > 8.0 units/mg protein (5.0-15.0 mg/mL). Storage: 2-8°C. Form: ammonium sulfate suspension. Source: E. coli. Species: Streptococcus pyogenes. hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase. Cat No: NATE-0346. | |
| Hyaluronate lyase from Streptomyces coelicolor, Recombinant | Hyaluronate lyase degrades hyaluronate using an elimination reaction to break glycosidic linkages yielding unsaturated disaccharide products. Group: Enzymes. Synonyms: hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase. Enzyme Commission Number: EC 4.2.2.1. CAS No. 37259-53-3. Purity: > 95 % as judged by SDS-PAGE. Hyaluronate Lyase. Mole weight: 82914.2 Da. Activity: 8.1 U/mg. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Streptomyces coelicolor A3(2). hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase. Cat No: NATE-1211. | |
| Hyaluronidase | Hyaluronidase. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EC 4.2.2.1;HYALURONATE LYASE;Hyaluronidase(fromtestes);hyaluronidasefromstreptomyceshyaluro-lyticus;Mucinase;Hyaluronidase Streptomyces hyalurolyticus;HYALURONATE LYASE FROM STREPTOMYCES*HYAL UROLYTICUS;HYALURONIDASE FROM STREPTOMYCES HYALURO- LYTICUS, ~0.1U/VIAL. Product Category: Heterocyclic Organic Compound. Appearance: lyophilized powder. CAS No. 9001-54-1. Molecular formula: n.a. Mole weight: 0. Product ID: ACM9001541. Alfa Chemistry ISO 9001:2015 Certified. | |
| MANS peptide | MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate ( MARCKS ), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis [1]. Uses: Scientific research. Group: Peptides. CAS No. 479482-23-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10218. | |
| MUC5AC motif peptide | MUC5AC motif peptide is a 16-amino acid fragment of mucin 5. Synonyms: Gly-Thr-Thr-Pro-Ser-Pro-Val-Pro-Thr-Thr-Ser-Thr-Thr-Ser-Ala-Pro. Grades: ≥95%. Molecular formula: C63H104N16O26. Mole weight: 1501.62. | |
| Mucicarmine | Mucicarmine is used in the histological visualization of acid mucopolysaccharides in tissue sections. Mucicarmine can identify mucin (deep rose), which is useful in determining the mucin positive cancer (such as liver carcinoma) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 51395-97-2. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-D1542. | |
| Native Aspergillus oryzae Protease | Protease catabolizes proteins by hydrolysis of peptide bonds. Protease, from Aspergillus oryzae, contains both endoprotease and exopeptidase activities. Fungal protease/peptidase complex produced by submerged fermentation of a selected strain of aspergillus oryzae and contains both endoprotease and exopeptidase activities. Applications: Protease is an enzyme used to break down proteins by hydrolyzing peptide bonds. protease is used to degrade proteins, to study protease inhibitors and to study thermal inactivation kinetics. protease is used in nucleic acid isolation procedures in incubations. this product is a fungal protease/peptidase complex produced by submerged fermentation of a selected strain of aspergillus oryzae. it has been injected into flies with a nanoject apparatus for infection and survival experiments. the enzyme from creative enzymes has been used in the semi-purification of mouse colorectal mucins during protein digestion. Group: Enzymes. Synonyms: Protease; Flavourzyme. CAS No. 9001-92-7. Protease. Source: Aspergillus oryzae. Protease; Flavourzyme. Cat No: NATE-0631. | |
| Native Clostridium perfringens (C. welchII) Neuraminidase Agarose | Neuraminidase enzymes are glycoside hydrolase enzymes (EC 3.2.1.18) that cleave the glycosidic linkages of neuraminic acids. Neuraminidase enzymes are a large family, found in a range of organisms. The best-known neuraminidase is the viral neuraminidase, a drug target for the prevention of the spread of influenza infection. The viral neuraminidases are frequently used as antigenic determinants found on the surface of the Influenza virus. Some variants of the influenza neuraminidase confer more virulence to the virus than others. Other homologs are found in mammalian cells, which have a range of functions. Neuraminidase enzymes are hydrolase enzymes that promo...cells. Group: Enzymes. Synonyms: neuraminidase; sialidase; α-neuraminidase; acetylneuraminidase; exo-α-sialidase; EC 3.2.1.18; 9001-67-6. Enzyme Commission Number: EC 3.2.1.18. CAS No. 9001-67-6. Neuraminidase. Activity: Type I, 6-10 units/mg protein (using 4MU-NANA), 2-5 units/mg protein (mucin); Type II, 10-20 units/mg protein (using 4MU-NANA), 3.5-8.0 units/mg protein (mucin); Type III, > 50 units/mg protein (using 4MU-NANA). Storage: -20°C. Form: lyophilized powder. Source: Clostridium perfringens (C. welchII). neuraminidase; sialidase; α-neuraminidase; acetylneuraminidase; exo-α-sialidase; EC 3.2.1.18; 9001-67-6. Cat No: NATE-0479. | |
| Native Human Cancer Antigen 125 | Cancer Antigen 125 (CA125) is a surface antigen associated with epithelial ovarian cancer. In serum, CA125 is associated with a high molecular weight glycoprotein. Published studies have indicated that elevated serum CA125 levels can be found in individuals with serious endometroid, clear-cell and undifferentiated ovarian carcinoma. Applications: Diagnostic controls; calibrators & standards; immunoassays; clinical chemistry; testing/assay validation; life science; elisa; blotting; manufacturing; tumor markers. Group: Others. Synonyms: MUCIN 16; muc16; CA-125; Cancer Antigen 125. Purity: > 95% (SDS-PAGE). Stability: 2 years. Storage: Store at -20°C. Form: Liquid in phosphate buffered saline, pH 7.4 with sucrose. Source: Human Ascites Fluid. Species: Human. MUCIN 16; muc16; CA-125; Cancer Antigen 125; MUC16. Cat No: NATE-0952. | |
| Native Human Cancer Antigen 15-3 | Native Human Cancer Antigen 15-3. Applications: Turbid, light yellow solution. Group: Others. Synonyms: CA 15-3; Tumor Marker 15-3; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Breast Tumor Antigen. CA 15-3. Activity: > 5,000 IU/mL. Stability: 2 years. Storage: at -20°C. Form: Solution in 1 M sodium chloride, 1% Triton(TM) X-100, 0.05% sodium azide, pH 7.4. Source: Human Ascites Fluid. CA 15-3; Tumor Marker 15-3; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Breast Tumor Antigen. Cat No: NATE-1929. | |
| Native Human Cancer Antigen 19-9 | Cancer Antigen 19-9 is a tumor marker elevated in blood of patients with carcinoma of the gastro-intestinal tract. Primarily used distinguishing pancreatic cancer from pancreatitis, CA 19-9 is not sufficiently specific for use as a cancer screening test. The specificity for pancreatic cancer increases with increasing levels, high levels showing a specificity of >97% for tumor presence. CA 19-9 can be elevated in many types of gastrointestinal cancer, such as colorectal cancer, esophageal cancer and hepatocellular carcinoma. A group of mucin type glycoprotein Sialosyl Lewis Antigens (SLA), such as CA19-9 and CA19-5, have come to be recognized as circulating cancer associated a...plications: Diagnostic controls; calibrators & standards; immunoassays; testing/assay validation; life science; validation studies; manufacturing; tumor markers. Group: Others. Synonyms: Tumor Marker 19-9; CA 19-9; Cancer Antigen 19-9; carbohydrate antigen 19-9; Sialylated Lewis (a) Antigen. Purity: High Purity - Low Cross Contamination of other cancer antigens (Gel filtration & ion-exchange chromatography). Activity: Typically > 500 kU/mL. Stability: 2 years. Appearance: Clear and Colorless. Storage: Store at -20°C. Form: Liquid in phosphate buffered saline, pH 7.4 with sucrose and 0.05% sodium azide. Source: Human Liver Metastases. Species: Human. Tumor Marker 19-9; CA 19-9 | |
| Obtusifolin | Obtusifolin, isolated from the seeds of Cassia obtusifolia , regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway [1]. Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein [2]. Uses: Scientific research. Group: Natural products. CAS No. 477-85-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-N2098. | |
| O-Glycosidase from Streptococcus pneumoniae, Recombinant | O-Glycosidase releases unsubstituted Ser-and Thr-linked β-Gal-(1?3)-α-GalNAc (Core 1 type O-glycan) from glycoproteins. Substitutions of the disaccharide core with sialic acid, lactosamine (galactose-N-acetyl glucosamine), or fucose will block hydrolysis and prevent the liberation of the oligosaccharide from the protein. Pretreament with glycolytic enzymes to remove substituent saccharides from the O-glycan may be needed prior to cleavage using O-glycosidase. Group: Enzymes. Synonyms: endo-α-acetylgalactosaminidase; endo-α-N-acetyl-D-galactosaminidase; mucinaminylserine mucinaminidase; D-galactosyl-3-(N-acetyl-α-D-galacto. Enzyme Commission Number: EC 3.2.1.97. CAS No. 9032-92-2. O-Glycosidase. Storage: 2-8°C. Form: buffered aqueous solution; Solution in 50 mM sodium phosphate, pH 7.5. Source: E. coli. Species: Streptococcus pneumoniae. endo-α-acetylgalactosaminidase; endo-α-N-acetyl-D-galactosaminidase; mucinaminylserine mucinaminidase; D-galactosyl-3-(N-acetyl-α-D-galactosaminyl)-L-serine mucinaminohydrolase; endo-α-GalNAc-ase; glycopeptide α-N-acetylgalactosaminidase; D-galactosyl-N-acetyl-α-D-galactosamine D-galactosyl-N-acetyl-galactosaminohydrolase; 9032-92-2; EC 3.2.1.97. Pack: Supplied with 5× Reaction Buffer, 250 mM NaH2PO4 pH 5.0. Cat No: NATE-0497. | |
| OV-1, sheep | OV-1, sheep is an alpha-helical antimicrobial ovispirin peptide derived from SMAP29 peptide (sheep) that inhibits a variety of drug-resistant strains, including mucinous and non-mucinous Pseudomonas aeruginosa. Synonyms: Lys-Asn-Leu-Arg-Arg-Ile-Ile-Arg-Lys-Ile-Ile-His-Ile-Ile-Lys-Lys-Tyr-Gly; L-lysyl-L-asparagyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-arginyl-L-lysyl-L-isoleucyl-L-isoleucyl-L-histidyl-L-isoleucyl-L-isoleucyl-L-lysyl-L-lysyl-L-tyrosyl-glycine. Grades: ≥95%. CAS No. 326855-45-2. Molecular formula: C105H188N34O21. Mole weight: 2262.83. | |
| Ox bile extract powder | Bile Extract Powder (Ox Bile Desiccated), dried or desiccated which contains ox bile acids. This powder is specifically been developed for Pharmaceutical Industry, which is prepared by a low temperature dehydration process which ensures a uniform product. Bile Extract Powder, dried is a mixture of conjugated bile acids (Cholic Acid, Deoxycholic Acid, Taurocholic and Glycocholic Acids). It is a straight forward drying of Ox Bile liquid, which contains all of the constituents characteristics, found in Ox Bile. None of the bile salts, bile pigments cholesterol, mucin, etc. has been removed. Applications: Bile extract powder is used to emulsify lipids in food passing through the intestine to enable fat digestion and absorption through the intestinal wall. bile salts aid in the breakdown of saturated fats that the digestive system has not been able to convert into unsaturated fats. the body uses these unsaturated fats to manufacture essential vitamins and hormones. many individuals without proper gallbladder function find it helpful to supplement with the best bile salts. Group: Others. Synonyms: Ox bile extract; Ox bile; BILE SALT; Ox . Ox bile extract powder. Activity: Cholic acid 40%-55%. Appearance: Greenish to yellowish colour free flowing powder. Source: Ox bile. Ox bile extract powder; Ox bile extract; Ox bile; BILE SALT; Ox bile powder. Cat No: OBE-001. | |
| Platycodin D3 | Platycodin D3 has anti-hepatitis C virus (HCV) activity. It can be used as an expectorant in a variety of lung inflammatory diseases and regulate the production and secretion of mucin in the airway. Platycodin D3 is a triterpenoid compound and an inhibitor of NF-κB. Synonyms: Olean-12-en-28-oic acid, 3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-2,16,23,24-tetrahydroxy-, O-D-apio-β-D-furanosyl-(1?3)-O-β-D-xylopyranosyl-(1?4)-O-6-deoxy-α-L-mannopyranosyl-(1?2)-α-L-arabinopyranosyl ester, (2β,3β,16α)-; 3-O-[(2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-β-D-xylopyranosyl-(1->4)-6-deoxy-α-L-mannopyranosyl-(1->2)-1-O-[(2β,3β,16α)-3-{[6-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl]oxy}-2,16,23,24-tetrahydroxy-28-oxoolean-12-en-28-yl]-α-L-arabinopyranose. Grades: >98%. CAS No. 67884-03-1. Molecular formula: C63H102O33. Mole weight: 1387.46. | |
| polypeptide N-acetylgalactosaminyltransferase | Requires both Mn2+ and Ca2+. The glycosyl residue is transferred to threonine or serine hydroxy groups on the polypeptide core of submaxillary mucin, κ-casein, apofetuin and some other acceptors of high molecular mass. Group: Enzymes. Synonyms: protein-UDP acetylgalactosaminyltransferase; UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase; UDP-N-acetylgalactosamine:κ-casein polypeptide N-acetylgalactosaminyltransferase; uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase; glycoprotein acet. Enzyme Commission Number: EC 2.4.1.41. CAS No. 9075-15-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2588; polypeptide N-acetylgalactosaminyltransferase; EC 2.4.1.41; 9075-15-4; protein-UDP acetylgalactosaminyltransferase; UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase; UDP-N-acetylgalactosamine:κ-casein polypeptide N-acetylgalactosaminyltransferase; uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase; glycoprotein acetylgalactosaminyltransferase; polypeptide-N-acetylgalactosamine transferase; UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase; UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase; UDP-GalNAc:polypeptide N-acetylgalactosami | |
| Recoflavone | Recoflavone, also referred to DA 6034, is a synthetic flavonoid derivative known to possess anti-inflammatory activity in phase ? clinical trials for the treatment of inflammatory bowel disease. With gastroprotective and ulcer healing activity, Recoflavone promotes gastric epithelial cell migration and wound-healing through the mTOR pathway, and induced mucin secretion via Ca2+-dependent pathways through P2Y receptor stimulation. Synonyms: DA-6034; DA 6034; DA6034; Recoflavone; 2-[2-(3,4-dimethoxyphenyl)-5-methoxy-4-oxochromen-7-yl]oxyacetic acid; 7-carboxymethoxyloxy-3',4',5-trimethoxyflavone;recoflavone. Grades: >98%. CAS No. 203191-10-0. Molecular formula: C20H18O8. Mole weight: 386.356. | |
| Ro 106-9920 | Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1 β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS. Group: Biochemicals. Alternative Names: 6- (Phenylsulfinyl) tetrazolo[1, 5-b]pyridazine. Grades: Highly Purified. CAS No. 62645-28-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Sabatolimab | Sabatolimab is a humanized monoclonal antibody directed against human T-cell immunoglobulin domain and mucin domain-3 (TIM-3). Sabatolimab has been approved for the treatment of adult patients with myelodysplastic syndromes (MDS). Synonyms: MBG453; NVP-MBG453. CAS No. 2252262-24-9. | |
| Talniflumate | Talniflumate is a calcium-activated chloride channel (CaCC) (hCLCA1/mCLCA3) blocker. It decreases mucin synthesis and release in cell culture and animal models. Talniflumate inhibits cyclooxygenases and Cl-/HCO3- exchanger activity to produce anti-inflammatory actions. Talniflumate also increases survival in a cystic fibrosis mouse model of distal intestinal obstructive syndrome. Uses: Anti-inflammatory agent. Synonyms: 2-[[3-(Trifluoromethyl)phenyl]amino]-1,3-dihydro-3-oxo-1-isobenzofuranyl 3-pyridinecarboxylic acid ester; Somalgen; Lomucin; (3-oxo-1H-2-benzofuran-1-yl) 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylate. Grades: ≥99% by HPLC. CAS No. 66898-62-2. Molecular formula: C21H13F3N2O4. Mole weight: 414.34. | |
| Ubamatamab | Ubamatamab (REGN4018) is a humanized bispecific antibody targeted against Mucin 16 (MUC16) and CD3. Ubamatamab demonstrates potent antitumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN4018. CAS No. 2305629-50-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99539. | |
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