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| Product | Description | |
|---|---|---|
| Recombinant Aspartate transaminase from Mycobacterium tuberculosis | Aspartate transaminase catalyzes the reversible transfer of an α-amino group between aspartate and glutamate and, as such, is an important enzyme in amino acid metabolism. Group: Enzymes. Synonyms: EC 2.6.1.1; AAT; AspT; AST; GOT (enzyme); oxaloacetate transferase; aspartate:2-oxoglutaRate aminotransferase; glutamate oxaloacetate transaminase; 9000-97-9. Enzyme Commission Number: EC 2.6.1.1. CAS No. 9000-97-9. Purity: > 80 %. AST. Mole weight: 47 kDa. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: Mycobacterium tuberculosis. EC 2.6.1.1; AAT; AspT; AST; GOT (enzyme); oxaloacetate transferase; aspartate:2-oxoglutaRate aminotransferase; glutamate oxaloacetate transaminase; 9000-97-9. Cat No: NATE-1017. |  |
| Recombinant Imidazoleglycerol-phosphate dehydratase from Mycobacterium tuberculosis | Imidazole glycerol-phosphate dehydratase (IGPD) catalyzes the sixth step of histidine biosynthesis. The enzyme is of fundamental biochemical interest, because it catalyzes removal of a non-acidic hydrogen atom in the dehydration reaction. Group: Enzymes. Synonyms: IGPD; EC 4.2.1.19; 9024-35-5; IGP dehydratase; D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase. Enzyme Commission Number: EC 4.2.1.19. CAS No. 9024-35-5. Purity: > 80 %. IGPD. Mole weight: 25 kDa. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: Mycobacterium tuberculosis. IGPD; EC 4.2.1.19; 9024-35-5; IGP dehydratase; D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase. Cat No: NATE-1015. | |
| Recombinant Ketol-acid reductoisomerase from Mycobacterium tuberculosis | Ketol-acid reductoisomerase catalyzes two steps in the biosynthesis of branched-chain amino acids. Group: Enzymes. Synonyms: dihydroxyisovalerate dehydrogenase (isomerizing); acetohydroxy acid isomeroreductase; ketol acid reductoisomerase; alpha-keto-beta-hydroxylacyl reductoisomerase; 2-hydroxy-3-keto acid reductoisomerase; acetohydroxy acid reductoisomerase; acetolactate reductoisomerase; dihydroxyisovalerate (isomerizing) dehydrogenase; isomeroreductase; reductoisomerase; EC 1.1.1.86. Enzyme Commission Number: EC 1.1.1.86. CAS No. 9075-2-9. Purity: > 80 %. Ketol-acid reductoisomerase. Mole weight: 38 kDa. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: Mycobacterium tuberculosis. dihydroxyisovalerate dehydrogenase (isomerizing); acetohydroxy acid isomeroreductase; ketol acid reductoisomerase; alpha-keto-beta-hydroxylacyl reductoisomerase; 2-hydroxy-3-keto acid reductoisomerase; acetohydroxy acid reductoisomerase; acetolactate reductoisomerase; dihydroxyisovalerate (isomerizing) dehydrogenase; isomeroreductase; reductoisomerase; EC 1.1.1.86. Cat No: NATE-1016. | |
| Recombinant phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis | Coenzyme A is involved in a great number of metabolic pathways, in particular it participates in the synthesis of the cell wall components of mycobacteria. Therefore PPAT is a very promising target in the search for antituberculosis drugs. PPAT catalyzes the fourth stage of coenzyme A biosynthesis. Group: Enzymes. Synonyms: 3'-dephospho-CoA pyrophosphorylase; Dephospho-CoA diphosphorylase; Dephospho-CoA pyrophosphorylase; Dephospho-coenzyme A pyrophosphorylase; Phosphopantetheine adenylyltransferase; PPAT; EC 2.7.7.3. Enzyme Commission Number: EC 2.7.7.3. CAS No. 9026-99-7. Purity: > 80 %. PPAT. Mole weight: 17.6 kDa. Activity: 42 U/mg. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: Mycobacterium tuberculosis. 3'-dephospho-CoA pyrophosphorylase; Dephospho-CoA diphosphorylase; Dephospho-CoA pyrophosphorylase; Dephospho-coenzyme A pyrophosphorylase; Phosphopantetheine adenylyltransferase; PPAT; EC 2.7.7.3. Cat No: NATE-1011. | |
| Recombinant Ser/Thr protein kinase from Mycobacterium tuberculosis) | A serine/threonine protein kinase (EC 2.7.11.1) is a kinase enzyme that phosphorylates the OH group of serine or threonine (which have similar sidechains). At least 125 of the 500+ human protein kinases are serine/threonine kinases (STK). Group: Enzymes. Synonyms: Protein phosphokinase; Protein serine kinase; Protein serine-threonine kinase; Protein-serine kinase; Serine kinase; Serine protein kinase; Serine(threonine) protein kinase; Serine-specific protein kinase; Serine/threonine protein kinase; Threonine-specific protein kinase; EC 2.7.11.1; STK. Enzyme Commission Number: EC 2.7.11.1. CAS No. 9026-43-1. Purity: > 95 %. STK. Mole weight: 51 kDa. Activity: 13 U/mg. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: Mycobacterium tuberculosis. Protein phosphokinase; Protein serine kinase; Protein serine-threonine kinase; Protein-serine kinase; Serine kinase; Serine protein kinase; Serine(threonine) protein kinase; Serine-specific protein kinase; Serine/threonine protein kinase; Threonine-specific protein kinase; EC 2.7.11.1; STK. Cat No: NATE-1013. | |
| Trehalose-phosphatase from Mycobacterium tuberculosis, Recombinant | In enzymology, a trehalose-phosphatase (EC 3.1.3.12) is an enzyme that catalyzes the chemical reaction: alpha,alpha-trehalose 6-phosphate + H2O <-> alpha,alpha-trehalose + phosphate. Thus, the two substrates of this enzyme are alpha,alpha'-trehalose 6-phosphate and H2O, whereas its two products are alpha,alpha-trehalose and phosphate. This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. Group: Enzymes. Synonyms: Trehalose 6-phosphatase; trehalose 6-phosphate phosphatase; trehalose-6-phosphate phosphohydrolase; TPP; T6PP. Enzyme Commission Number: EC 3.1.3.12. CAS No. 9025-72-3. Purity: >95 % as judged by SDS-PAGE. T6PP. Mole weight: 61948.7 Da. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Mycobacterium tuberculosis H37Rv. Trehalose 6-phosphatase; trehalose 6-phosphate phosphatase; trehalose-6-phosphate phosphohydrolase; TPP; T6PP. Cat No: NATE-1232. | |
| 1-13C-D-Phenylalanine | 1-13C-D-Phenylalanine is labelled D-Phenylalanine (P319410), the stereoisomer of L-Phenylalanine (P319415) which has been used in the synthesis of Schaeffers acid analogues as important structures in tuberculostatic design. They exhibit the ability to inhibit Mycobacterium tuberculosis type II dehydroquinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1202063-94-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C813CH11NO2, Molecular Weight: 166.18. US Biological Life Sciences. |  Worldwide |
| 1,2,4-Oxadiazole | 1,2,4-Oxadiazole can be used in biological study of antitubercular activity of butyrate-specific oxadiazoles against Mycobacterium tuberculosis and their cytotoxicity on monkey kidney cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 288-90-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C2H2N2O, Molecular Weight: 70.05. US Biological Life Sciences. | Worldwide |
| 1-[4-[ (Tetrahydro-2H-pyran-2-yl) oxy]phenyl]-4-[4- (trifluoromethoxy) phenoxy]piperidine | 1-[4-[ (Tetrahydro-2H-pyran-2-yl) oxy]phenyl]-4-[4- (trifluoromethoxy) phenoxy]piperidine is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 681482-80-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C23H26F3NO4. US Biological Life Sciences. | Worldwide |
| 16S rRNA (cytidine1409-2'-O)-methyltransferase | The bifunctional enzyme from Mycobacterium tuberculosis 2'-O-methylates cytidine1409 in helix 44 of 16S rRNA and cytidine1920 in helix 69 of 23S rRNA (cf. EC 2.1.1.226, 23S rRNA (cytidine1920-2'-O)-methyltransferase). Group: Enzymes. Synonyms: TlyA (ambiguous). Enzyme Commission Number: EC 2.1.1.227. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1830; 16S rRNA (cytidine1409-2'-O)-methyltransferase; EC 2.1.1.227; TlyA (ambiguous). Cat No: EXWM-1830. | |
| 1-Chloro-N,N-2-trimethylpropenylamine | 1-Chloro-N,N-2-trimethylpropenylamine acts as a reagent in the synthesis and antitumor activity of (-)-bassianolide in human cancer cells through cell cycle arrest. Enantioselective total synthesis of nannocystins A and A0 as elongation factor 1 inhibitors. Total synthesis of (-)-caprazamycin A with antibacterial activity against Mycobacterium tuberculosis (TB) via diastereoselective aldol reaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 26189-59-3. Pack Sizes: 500mg, 1g. Molecular Formula: C6H12ClN. US Biological Life Sciences. | Worldwide |
| 2- [ (1, 4-Dioxido-2-quinoxalinyl) methylene] hydrazinecarbonyl-oxy-hexanoic Acid | 2- [ (1, 4-Dioxido-2-quinoxalinyl) methylene] hydrazinecarbonyl-oxy-hexanoic Acid is a derivative of 2- [ (1, 4-Dioxido-2-quinoxalinyl) methylene] hydrazinecarbonyl-oxy-propanoic Acid (D486495), which is a derivative of Quindoxin (Q700325), that is a potential anti-bacterial agent with a wide range biological properties. Also, it potentially display anti-malarial, anti-leishmanial and anti-tuberculosis activity. Potent anti-mycobacterium tuberculosis agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H18N4O6, Molecular Weight: 362.34. US Biological Life Sciences. | Worldwide |
| 2- [ (1, 4-Dioxido-2-quinoxalinyl) methylene] hydrazinecarbonyl-oxy-propanoic Acid | 2- [ (1, 4-Dioxido-2-quinoxalinyl) methylene] hydrazinecarbonyl-oxy-propanoic Acid is a derivative of Quindoxin (Q700325), which is a potential anti-bacterial agent with a wide range biological properties. Also, it potentially display anti-malarial, anti-leishmanial and anti-tuberculosis activity. Potent anti-mycobacterium tuberculosis agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C13H12N4O6, Molecular Weight: 320.26. US Biological Life Sciences. | Worldwide |
| 2- [ (1, 4-Dioxido-2-quinoxalinyl) methylene] hydrazinecarbonyloxy-propyl-amine | 2- [ (1, 4-Dioxido-2-quinoxalinyl) methylene] hydrazinecarbonyloxy-propyl-amine is a derivative of Quindoxin (Q700325), which is a potential anti-bacterial agent with a wide range biological properties. Also, it potentially display anti-malarial, anti-leishmanial and anti-tuberculosis activity. Potent anti-mycobacterium tuberculosis agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C13H15N5O4, Molecular Weight: 305.29. US Biological Life Sciences. | Worldwide |
| 2- [ (1, 4-Dioxido-2-quinoxalinyl) methylene] hydrazinecarbonyloxy-propyl-thiol | 2- [ (1, 4-Dioxido-2-quinoxalinyl) methylene] hydrazinecarbonyloxy-propyl-thiol is a derivative of Quindoxin (Q700325), which is a potential anti-bacterial agent with a wide range biological properties. Also, it potentially display anti-malarial, anti-leishmanial and anti-tuberculosis activity. Potent anti-mycobacterium tuberculosis agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C13H14N4O4S, Molecular Weight: 322.339999999999. US Biological Life Sciences. | Worldwide |
| (21E/Z,36Z)-2-Docosyl-3-hydroxy-21,36-pentapentacontadienoic Acid | (21E/Z,36Z)-2-Docosyl-3-hydroxy-21,36-pentapentacontadienoic Acid is one of many mycolic acids found in the outer membrane of Mycobacterium tuberculosis. These are 2-alkyl, 3-hydroxy long chain fatty acids that are involved in the permeability of the mycobacterial cell envelope, and are essential to the bacterial survival. Group: Biochemicals. Grades: Highly Purified. CAS No. 958726-09-5. Pack Sizes: 500ug, 1mg. Molecular Formula: C77H150O3, Molecular Weight: 1124.01. US Biological Life Sciences. | Worldwide |
| 2,3-Dihydrobenzofuran-4-carbaldehyde | 2,3-Dihydrobenzofuran-4-carbaldehyde is used in the synthesis of macroline derivatives as inhibitors of mycobacterium tuberculosis protein tyrosine phosphatase B. Group: Biochemicals. Grades: Highly Purified. CAS No. 209256-42-8. Pack Sizes: 250mg, 2.5g. Molecular Formula: C9H8O2, Molecular Weight: 148.16. US Biological Life Sciences. | Worldwide |
| 23S rRNA (cytidine1920-2'-O)-methyltransferase | The bifunctional enzyme from Mycobacterium tuberculosis 2'-O-methylates cytidine1920 in helix 69 of 23S rRNA and cytidine1409 in helix 44 of 16S rRNA (cf. EC 2.1.1.227, 16S rRNA (cytidine1409-2'-O)-methyltransferase). These methylations result in increased susceptibility to the antibiotics capreomycin and viomycin. Group: Enzymes. Synonyms: TlyA (ambiguous). Enzyme Commission Number: EC 2.1.1.226. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1829; 23S rRNA (cytidine1920-2'-O)-methyltransferase; EC 2.1.1.226; TlyA (ambiguous). Cat No: EXWM-1829. | |
| 25-Desacetyl Rifampicin | A metabolite of Rifabutin. Rifabutin is an antibiotic used to treat tuberculosis and prevent and treat Mycobacterium avium complex. Synonyms: 25-O-Deacetyl-3-[(E)-[(4-methyl-1-piperazinyl)imino]methyl]rifamycin; 25-Deacetylrifampicin; 25-Desacetylrifampin; 25-O-Deacetylrifampicin; 25-O-Desacetylrifampin; Deacetylrifampicin; Deacetylrifampin; Desacetylrifampicin; Desacetylrifampin. Grades: > 95%. CAS No. 16783-99-6. Molecular formula: C41H56N4O11. Mole weight: 780.92. |  |
| 2,5-Dihydroxybenzaldehyde | 2,5-Dihydroxybenzaldehyde (Gentisaldehyde) is a naturally occurring antimicrobial that inhibits the growth of Mycobacterium avium subsp. paratuberculosis. 2,5-Dihydroxybenzaldehyde is active against S. aureus strains with a MIC 50 of 500 mg/L [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Gentisaldehyde. CAS No. 1194-98-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N1673. |  |
| 2-[[ (5-Nitro-2-thiazolyl) amino]carbonyl]phenyl 2-(acetyloxy)benzoate | 2-[[ (5-Nitro-2-thiazolyl) amino]carbonyl]phenyl 2-(acetyloxy)benzoate is an impurity of Nitazoxanide (N490100), an anthelmintic (cestodes), antiprotozoal (cryptosporidium). Kills Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 952686-58-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C19H13N3O7S. US Biological Life Sciences. | Worldwide |
| 25-O-Deacetyl-23-O-acetyl Rifabutin | A metabolite of Rifabutin. Rifabutin is an antibiotic used to treat tuberculosis and prevent and treat Mycobacterium avium complex. Grades: > 95%. CAS No. 1242076-43-2. Molecular formula: C46H62N4O11. Mole weight: 847.03. | |
| 2-Amino-5-chlorobenzamide | 2-Amino-5-chlorobenzamide can be used in a fragment-based approach to investigate Mycobacterium tuberculosis CYP121 inhibitors. It it also a useful reagent for the enantioselective synthesis of fluoro-dihydroquinazolones and -benzooxazinones. Group: Biochemicals. Grades: Highly Purified. CAS No. 5202-85-7. Pack Sizes: 500mg, 1g. Molecular Formula: C7H7ClN2O, Molecular Weight: 170.6. US Biological Life Sciences. | Worldwide |
| 2-Chloro-1-[[(2R)-2-methyloxiranyl]methyl]-4-nitro-1H-imidazole | 2-Chloro-1-[[(2R)-2-methyloxiranyl]methyl]-4-nitro-1H-imidazole is an intermediate in the synthesis of Delamanid, a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 681490-93-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C7H8ClN3O3. US Biological Life Sciences. | Worldwide |
| 2-Cyano-6-methoxybenzothiazole | 2-Cyano-6-methoxybenzothiazole is a key intermediate in the synthesis of fireflys luciferol, the light emitting chemical. Also a reactant in the preparation of 1,2,4-Oxadiazole EthR inhibitors used in the effort to improve the sensitivity of the human pathogen mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 943-03-3. Pack Sizes: 500mg, 1g. Molecular Formula: C9H6N2OS, Molecular Weight: 190.22. US Biological Life Sciences. | Worldwide |
| 2-Mercaptopyridine N-oxide sodium | 2-Mercaptopyridine N-oxide sodium has bactericidal effect and is against a standard strain of Mycobacterium tuberculosis H37Rv (ATCC 27294) with MIC 90 of 7.20 μM. 2-Mercaptopyridine N-oxide sodium and its complex with iron, gallium, and bismuth have good anti-M. tuberculosis activity. 2-Mercaptopyridine N-oxide sodium has potential for the treatment of tuberculosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3811-73-2. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-125785A. | |
| 2-Methyl-D-phenylalanine | 2-Methyl-D-phenylalanine is a derivative of D-Phenylalanine, the stereoisomer of L-Phenylalanine used in the synthesis of Schaeffer's acid analogs as important structures in tuberculostatic design. These analogs exhibit the ability to inhibit Mycobacterium tuberculosis type II dehydroquinase. Synonyms: D-Phe(2-Me)-OH; o-Methyl-D-phenylalanine; (R)-2-Amino-3-(2-methylphenyl)propanoic acid; 2-Methylphenyl-D-alanine; H O ME D PHE OH; D-2-Methylphenylalanine; D-Phenylalanine, 2-methyl-; D-2-METHYLPHE; H-D-PHE(2-ME)-OH; H-O-ME-D-PHE-OH; D-2-ME-PHE-OH; D-PHE(2-ME)-OH; (2R)-2-amino-3-(2-methylphenyl)propanoic acid. Grades: ≥ 98% (HPLC, Chiral purity). CAS No. 80126-54-1. Molecular formula: C10H13NO2. Mole weight: 179.23. | |
| 2-nitroimidazole nitrohydrolase | The enzyme catalyses the initial step in the biodegradation of 2-nitroimidazole by the soil bacterium Mycobacterium sp. JS330. Group: Enzymes. Synonyms: NnhA; 2NI nitrohydrolase; 2NI denitrase. Enzyme Commission Number: EC 3.5.99.9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4592; 2-nitroimidazole nitrohydrolase; EC 3.5.99.9; NnhA; 2NI nitrohydrolase; 2NI denitrase. Cat No: EXWM-4592. | |
| (2R)-2-Hydroxy-4-[(4-methoxyphenyl)methoxy]-N,N,N-trimethyl-4-oxo-1-butanaminium Chloride | (2R)-2-Hydroxy-4-[(4-methoxyphenyl)methoxy]-N,N,N-trimethyl-4-oxo-1-butanaminium Chloride is an substituent found to improve inhibitory properties of phenothiazine derivatives in Mycobacterium Tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1135366-22-1. Pack Sizes: 100mg, 1g. Molecular Formula: C15H24ClNO4. US Biological Life Sciences. | Worldwide |
| (2R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-1,2-propanediol | (2R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-1,2-propanediol is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 681490-91-5. Pack Sizes: 10mg, 25mg. Molecular Formula: C7H10ClN3O4. US Biological Life Sciences. | Worldwide |
| (2R,5R)-Avibactam Sodium Salt | (2R,5R)-Avibactam Sodium Salt is an isomer of Avibactam Sodium Salt (A794850); a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1797133-98-2. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C7H10N3NaO6S, Molecular Weight: 287.23. US Biological Life Sciences. | Worldwide |
| (2S)-5-[(Phenylmethoxy)imino]-2-piperidinecarboxylic Acid Ethyl Ester | (2S)-5-[(Phenylmethoxy)imino]-2-piperidinecarboxylic Acid Ethyl Ester is an impurity of Avibactam (A794850, Na Salt); a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1416134-60-5. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C15H20N2O3, Molecular Weight: 276.33. US Biological Life Sciences. | Worldwide |
| (2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxamide | (2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxamide is an impurity of Avibactam (A794850, Na Salt); a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1416134-49-0. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C13H19N3O2, Molecular Weight: 249.31. US Biological Life Sciences. | Worldwide |
| (2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxylic Acid Ethyl Ester Ethanedioate | (2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxylic Acid Ethyl Ester Ethanedioate is an impurity of Avibactam (A794850, Na Salt); a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1416134-48-9. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C15H22N2O3 (C2H2O4), Molecular Weight: 278.359002999999. US Biological Life Sciences. | Worldwide |
| (2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxylic Acid Methyl Ester | (2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxylic Acid Methyl Ester is an impurity of Avibactam (A794850, Na Salt); a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1416134-73-0. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C14H20N2O3, Molecular Weight: 264.32. US Biological Life Sciences. | Worldwide |
| (2S, 5R)-6-(Benzyloxy)-7-oxo-1, 6-diazabicyclo[3. 2. 1]octane-2-carboxamide | (2S, 5R)-6-(Benzyloxy)-7-oxo-1, 6-diazabicyclo[3. 2. 1]octane-2-carboxamide is an impurity of Avibactam (A794850, Na Salt); a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1192651-49-2. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C14H17N3O3, Molecular Weight: 275.3. US Biological Life Sciences. | Worldwide |
| (2S, 5R)-6-Hydroxy-7-oxo-1, 6-diazabicyclo[3. 2. 1]octane-2-carboxamide | (2S, 5R)-6-Hydroxy-7-oxo-1, 6-diazabicyclo[3. 2. 1]octane-2-carboxamide is an impurity of Avibactam (A794850, Na Salt); a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1383814-64-9. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C7H11N3O3, Molecular Weight: 185.18. US Biological Life Sciences. | Worldwide |
| (2S,5S)-Avibactam Sodium Salt | (2S,5S)-Avibactam Sodium Salt is an isomer of Avibactam Sodium Salt; a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 2064219-26-5. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C7H10N3NaO6S, Molecular Weight: 287.23. US Biological Life Sciences. | Worldwide |
| 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate-CoA ligase | The enzyme, characterized from actinobacterium Mycobacterium tuberculosis, catalyses a step in the degradation of cholesterol and cholate. The enzyme is very specific for its substrate, and requires that the side chain at C17 is completely removed. Group: Enzymes. Synonyms: fadD3 (gene name); HIP-CoA ligase. Enzyme Commission Number: EC 6.2.1.41. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5700; 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate-CoA ligase; EC 6.2.1.41; fadD3 (gene name); HIP-CoA ligase. Cat No: EXWM-5700. | |
| (3 β ) -24-Bromo-3-[ (tert-butyl) dimethylsilyloxy]-chol-5-ene | (3 β ) -24-Bromo-3-[ (tert-butyl) dimethylsilyloxy]-chol-5-ene is a reactant used in the preparation of series of cholesterol side-chain analogs used in studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P 450 enzymes CYP124A1, CYP125A1 and CYP142A1. Group: Biochemicals. Alternative Names: (3 β ) -24-Bromo-3-[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]-chol-5-ene. Grades: Highly Purified. CAS No. 1384736-07-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (3 β)-24-Bromochol-5-en-3-ol | (3 β)-24-Bromochol-5-en-3-ol is used as an substrate in the study of ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P450 enzymes. Group: Biochemicals. Grades: Highly Purified. CAS No. 74041-57-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (3 β)-3-O-tert-Butyldimethylsilyl-cholest-5-ene-3,24-diol | (3 β)-3-O-tert-Butyldimethylsilyl-cholest-5-ene-3,24-diol is a reactant used in the preparation of series of cholesterol side-chain analogs used in studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P 450 enzymes. It is used in the preparation of (25S)-Δ7-dafachronic acid, (25S)-Δ4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid. Group: Biochemicals. Alternative Names: (3 β ) -3-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-chol-5-en-24-ol. Grades: Highly Purified. CAS No. 84529-86-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 3-Bromobenzaldehyde | 3-Bromobenzaldehyde, is a substituted benzaldehyde, shown to have antibacterial activity against Mycobacterium tuberculosis. It is also a versatile building block, used in the synthesis of more complex pharmaceutical compounds. Group: Biochemicals. Alternative Names: m-Bromobenzaldehyde; 3-Formyl-1-bromobenzene; 3-Formylbromobenzene; 5-Bromobenzaldehyde; NSC 66828. Grades: Highly Purified. CAS No. 3132-99-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 3'-Deoxy-3'-fluorothymidine-5'-monophosphate-d3 Disodium Salt | A thymidine-5'-O-monophosphate analogue, for Mycobacterium tuberculosis thymidylate kinase inhibition. Synonyms: 3'-Deoxy-3'-fluoro-5'-thymidylic Acid-d3 Disodium; 2',3'-Dideoxy-3'-fluoro-5-methyluridine-d3 5'-(Dihydrogen Phosphate) Disodium; 3'-Deoxy-3'-fluoro-thymidine-d3 Monophosphate Disodium; 3'-Fluoro-3'-deoxythymidine-d3 Monophosphate Disodium. Molecular formula: C10H9D33FN2Na2O7P. Mole weight: 371.18. | |
| 3-Deoxy-3-fluorothymidine-5-monophosphate-d3 Disodium Salt | A thymidine-5'-O-monophosphate analogue as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Group: Biochemicals. Alternative Names: 3'-Deoxy-3'-fluoro-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 3'-Deoxy-3'-fluorothymidine-5'-monophosphate Disodium Salt | A thymidine-5'-O-monophosphate analogue as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Synonyms: 3'-Deoxy-3'-fluoro-5'-thymidylic Acid Disodium; 2',3'-Dideoxy-3'-fluoro-5-methyluridine 5'-(Dihydrogen Phosphate) Disodium; 3'-Deoxy-3'-fluorothymidine Monophosphate Disodium; 3'-Fluoro-3'-deoxythymidine Monophosphate Disodium. Grades: 95%. CAS No. 1316845-74-5. Molecular formula: C10H12FN2Na2O7P. Mole weight: 368.16. | |
| 3-Deoxy-3-fluorothymidine-5-monophosphate Disodium Salt | A thymidine-5'-O-monophosphate analogue as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Group: Biochemicals. Alternative Names: 3'-Deoxy-3'-fluoro-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 3-(Hydroxymethyl)phenylboronic acid | Reactant involved in: Copper-mediated trifluoromethylation Copper-catalyzed transformations from arylboronic acids in water Mitsunobu, Suzuki, and amidation reactions with hydroxyphenylamino bromopyrazinecarboxylateReactant involved in the synthesis of biologically active molecules including: Mycobacterium tuberculosis H37Rv chorismate mutase inhibitors via Suzuki coupling reactions HIV protease inhibitors with antiviral activity against drug-resistant viruses Pyrrole derivatives for use as PDE4B inhibitors. Synonyms: 3-Boronobenzyl alcohol; 3-hydroxymethylbenzeneboronic acid; 3-hydroxymethylboronic acid; RARECHEM AH PB 0189; 3-HydroMethylphenylboronicacid; KS-000000LJ; m-(Hydroxymethyl)phenyl boronic acid. Grades: 97%. CAS No. 87199-15-3. Molecular formula: C7H9BO3. Mole weight: 151.96. | |
| 3-ketosteroid 9α-monooxygenase | The enzyme is involved in the cholesterol degradation pathway of several bacterial pathogens, such as Mycobacterium tuberculosis. It is a two-component system consisting of a terminal oxygenase (KshA) and a ferredoxin reductase (KshB). The oxygenase contains a Rieske-type iron-sulfur center and non-heme iron. The reductase component is a flavoprotein containing an NAD-binding domain and a plant-type iron-sulfur cluster. The product of the enzyme is unstable, and spontaneously converts to 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione. Group: Enzymes. Synonyms: KshAB; 3-ketosteroid 9α-hydroxylase. Enzyme Commission Number: EC 1.14.13.142. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0742; 3-ketosteroid 9α-monooxygenase; EC 1.14.13.142; KshAB; 3-ketosteroid 9α-hydroxylase. Cat No: EXWM-0742. | |
| 3-oxocholest-4-en-26-oate-CoA ligase | The enzyme, characterized from actinobacterium Mycobacterium tuberculosis, catalyses a step in the degradation of cholesterol. It is responsible for the activation of the C8 side chain. 3β-hydroxycholest-5-en-26-oate can also be used as substrate. Group: Enzymes. Synonyms: fadD19 (gene name). Enzyme Commission Number: EC 6.2.1.42. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5701; 3-oxocholest-4-en-26-oate-CoA ligase; EC 6.2.1.42; fadD19 (gene name). Cat No: EXWM-5701. | |
| 4-Nitrophenyl a-D-mannopyranoside | 4-Nitrophenyl a-D-mannopyranoside - a sophisticated chemical compound of significance to the biomedical realm. Primarily, it serves as a substrate for β-mannosidase activity detection in biological samples, aiding in the maintenance of optimal health. However, this versatile compound also contributes to the fight against daunting drug-resistant strains of Mycobacterium tuberculosis by facilitating the development of synthetic inhibitors. Its potential for groundbreaking biomedical advancements cannot be overlooked. Synonyms: Man-a-PNP. CAS No. 10357-27-4. Molecular formula: C12H15NO8. Mole weight: 301.25. | |
| 5-Azido-5-deoxy Thymidine | It is a potential inhibitor of mycobacterium tuberculosis monophosphate kinase (TMPKmt). Synonyms: 5'-AZT; 5'-Azido-5'-deoxythymidine; NSC 254064; 5'-N3-5-Me-ddU; 5'-Azido-5-methyl-2',5'-dideoxyuridine; 1-((2R,4S,5R)-5-(azidomethyl)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 19316-85-9. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
| 5-Bromo-2'-deoxy-2'-fluorouridine | 5-Bromo-2'-deoxy-2'-fluorouridine is an analog of Uridine and used as a reagent in the synthesis of β-D-arabinofuranosyl and deoxyfluoro-β-D-ribofuranosyl pyrimidine nucleoside analogs which exhibit antituberculosis activity against Mycobacterium bovis, Mycobacterium tuberculosis and Mycobacterium avium in vitro. Synonyms: 5-Bromo-1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)uracil; 5-Bromo-2'-fluoro-2'-deoxyuridine; 5-Bromo-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 55612-18-5. Molecular formula: C9H10BrFN2O5. Mole weight: 325.09. | |
| 5-Deoxy-2-O-methanesulfonyl-5-tridecyl-D-ribofuranose | 5-Deoxy-2-O-methanesulfonyl-5-tridecyl-D-ribofuranose is a novel and intriguing biomedical compound having applications in research of drug-resistant bacterial infections, including the formidable Mycobacterium tuberculosis. The intricate mechanism of this compound lies in its ability to impede pivotal enzymes crucial to bacterial cell wall bioenhancement, culminating in an irreversible cessation of cellular vitality. Molecular formula: C19H38O6S. Mole weight: 394.57. | |
| 5-Fluoroindole | 5-Fluoroindole is an antibacterial agent, that inhibits Mycobacterium tuberculosis with a MIC of 4.7 μM. 5-Fluoroindole exhibits metabolic stability in rat liver microsomes. 5-Fluoroindole exhibits anti-tuberculosis efficacy in mice [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 399-52-0. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-40156. | |
| 5-Isopropyl-3-methylphenol | 5-Isopropyl-3-methylphenol is a derivative of Carvacrol (C184600); a major phenolic component of oregano oil and a novel inhibitor of the Mycobacterium tuberculosis (MTB) chorismate mutase (CM) enzyme. Group: Biochemicals. Grades: Highly Purified. CAS No. 3228-3-3. Pack Sizes: 2.5g, 25g. Molecular Formula: C10H14O, Molecular Weight: 150.22. US Biological Life Sciences. | Worldwide |
| 6-Deoxy-8-D-methylrabelomycin | 6-Deoxy-8-D-methylrabelomycin is produced by the strain of Streptomyces tsusimaensis M131038F7. It has anti-gram-positive bacteria activity and weak activity of anti-mycobacterium, gram-negative positive bacteria and candida albicans. Molecular formula: C20H16O5. Mole weight: 336.34. | |
| 7,8-dihydroneopterin epimerase | The enzyme, which has been characterized in bacteria and plants, also has the activity of EC 4.1.2.25, dihydroneopterin aldolase. The enzyme from the bacterium Mycobacterium tuberculosis has an additional oxygenase function (EC 1.13.11.81, 7,8-dihydroneopterin oxygenase). Group: Enzymes. Enzyme Commission Number: EC 5.1.99.8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5440; 7,8-dihydroneopterin epimerase; EC 5.1.99.8. Cat No: EXWM-5440. | |
| 7,8-dihydroneopterin oxygenase | The enzyme from the bacterium Mycobacterium tuberculosis is multifunctional and also catalyses the epimerisation of the 2'-hydroxy group of 7,8-dihydroneopterin (EC 5.1.99.8, 7,8-dihydroneopterin epimerase) and the reaction of EC 4.1.2.25 (dihydroneopterin aldolase). Group: Enzymes. Enzyme Commission Number: EC 1.13.11.81. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0602; 7,8-dihydroneopterin oxygenase; EC 1.13.11.81. Cat No: EXWM-0602. | |
| A-500359A | A-500359A is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has the activity of inhibiting translocase-1, IC50 is 0.017 μmol/L, and the IC50 of inhibiting peptidoglycan biosynthesis is 0.68 μmol/L. It also has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. CAS No. 254449-20-2. Molecular formula: C24H33N5O12. Mole weight: 583.54. | |
| A-500359C | A-500359C is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. CAS No. 254449-21-3. Molecular formula: C23H31N5O12. Mole weight: 569.52. | |
| A-500359D | A-500359D is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. CAS No. 254449-22-4. Molecular formula: C24H33N5O11. Mole weight: 567.54. | |
| A-500359E | A-500359E is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Synonyms: A-500359 E. Molecular formula: C18H23N3O12. Mole weight: 473.39. | |
| A-500359F | A-500359F is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Molecular formula: C17H21N3O12. Mole weight: 459.36. | |
| A-500359G | A-500359G is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Molecular formula: C22H29N5O12. Mole weight: 555.49. | |
| A-500359H | A-500359H is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Molecular formula: C16H19N3O12. Mole weight: 445.33. | |
| A-500359 M-1 | A-500359 M-1 is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Synonyms: N-[2- ({2-[ (6-{[ (2S, 3S, 4R, 5R) -5- (2, 4-Dioxo (1, 3-dihydropyrimidinyl) ) -4-hydroxy-3-methoxyoxolan-2-yl]carbamoylmethoxy} (4S, 5S, 6S) -4, 5-dihydroxy-4H-5, 6-dihydropyran-2-yl) carbonylamino]ethyl}disulfanyl) ethyl]acetamide. Molecular formula: C23H33N5O12S2. Mole weight: 635.66. | |
| A-500359 M-2 | A-500359 M-2 is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Synonyms: N-((3R,6R)-3-Methyl-5-oxo(1,4-thiazaperhydroepin-6-yl))(6-{[(2S,3S,4R,5R)-5-(2,4-dioxo(1,3-dihydropyrimidinyl))-4-hydroxy-3-methoxyoxolan-2-yl]carbamoylmethoxy}(4S,5S,6S)-4,5-dihydroxy(4H-5,6-dihydropyran-2-yl))carboxamide. Molecular formula: C23H31N5O12S. Mole weight: 601.58. | |
| Acethydrazide | Acethydrazide (CAS# 1068-57-1) is a metabolite of Isoniazid (I821450) an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Synonyms: acetohydrazide. Grades: 97 %. CAS No. 1068-57-1. Molecular formula: C2H6N2O. Mole weight: 74.08. | |
| Acetohydrazide | Acetohydrazide is a metabolite of Isoniazid (I821450) an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Group: Biochemicals. Alternative Names: Acetic Acid Hydrazide; Acethydrazide; Acetic hydrazide; Acetohydrazine; Acetyl hydrazide; Acetylhydrazine; ENT-61241; Ethanehydrazonic Acid; Monoacetylhydrazine; NSC 2271; NSC 53155. Grades: Highly Purified. CAS No. 1068-57-1. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
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