Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Neurokinin b | Neurokinin b. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NEUROMEDIN K; NEUROKININ B; DMHDFFVGLM-NH2; NEUROKININ K; Neurokinin B NKB; NKB. Product Category: Heterocyclic Organic Compound. CAS No. 86933-75-7. Molecular formula: C55H79N13O14S2. Mole weight: 1210.42. Purity: 0.96. IUPACName: 3-amino-4-[[1-[[1-[[1-[[1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-hydroxy-1,4-. Density: 1.313 g/cm³. Product ID: ACM86933757. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Neurokinin B | Neurokinin B, one of the tachykinin family of peptides, binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R to mediate their biological effect but shows preference for the NK-3 receptor. Uses: Neurotransmitter agents. Synonyms: NKB; H-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2; L-alpha-aspartyl-L-methionyl-L-histidyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide; Neurokinin K; Neurokinin beta; β-Neurokinin; Neuromedin K; (5S,8S,14S,17S,20S,23S,26S,29S,32S)-26-((1H-imidazol-4-yl)methyl)-32-amino-17,20-dibenzyl-5-carbamoyl-23-(carboxymethyl)-8-isobutyl-14-isopropyl-29-(2-(methylthio)ethyl)-7,10,13,16,19,22,25,28,31-nonaoxo-2-thia-6,9,12,15,18,21,24,27,30-nonaazatetratriacontan-34-oic acid. Grades: ≥95%. CAS No. 86933-75-7. Molecular formula: C55H79N13O14S2. Mole weight: 1210.42. |  |
| Neurokinin B acetate | Neurokinin B acetate, one of the tachykinin family of peptides, binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R to mediate their biological effect but shows preference for the NK-3 receptor. Synonyms: H-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2.CH3CO2H; L-alpha-aspartyl-L-methionyl-L-histidyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide acetic acid; Neurokinin B (swine spinal cord) acetate; Neurokinin B (human) acetate; Neurokinin B (pig spinal cord) acetate; Neurokinin B (porcine) acetate; Neurokinin β (pig spinal cord) acetate; Neuromedin K (pig spinal cord) acetate; Porcine neurokinin B acetate; Zneurok1 (human) acetate. Grades: ≥95%. Molecular formula: C57H83N13O16S2. Mole weight: 1270.48. | |
| Neurokinin B TFA | Neurokinin B TFA belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect [1]. Uses: Scientific research. Group: Peptides. CAS No. 101536-55-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0242A. |  |
| [Ala5, beta-Ala8]-Neurokinin A (4-10) | It is a potent and selective agonist of NK-2 receptor. Synonyms: L-alpha-aspartyl-L-alanyl-L-phenylalanyl-L-valyl-beta-alanyl-L-leucyl-L-methioninamide; L-Methioninamide, L-α-aspartyl-L-alanyl-L-phenylalanyl-L-valyl-β-alanyl-L-leucyl-; (5S,8S,15S,18S,21S,24S)-24-Amino-18-benzyl-5-carbamoyl-8-isobutyl-15-isopropyl-21-methyl-7,10,14,17,20,23-hexaoxo-2-thia-6,9,13,16,19,22-hexaazahexacosan-26-oic acid; Asp-Ala-Phe-Val-β-Ala-Leu-Met-NH2; [ala5,β-ala8]-α-neurokinin fragment 4-10. Grades: ≥95%. CAS No. 127633-71-0. Molecular formula: C35H56N8O9S. Mole weight: 764.93. | |
| [bAla8]-Neurokinin A (4-10) | An agonist of neurokinin 2 (NK2) receptor. Synonyms: MEN 10210; H-Asp-Ser-Phe-Val-bAla-Leu-Met-NH2; DSFVXLM; L-alpha-aspartyl-L-seryl-L-phenylalanyl-L-valyl-beta-alanyl-L-leucyl-L-methioninamide. Grades: ≥95%. CAS No. 122063-01-8. Molecular formula: C35H56N8O10S. Mole weight: 780.93. | |
| [bAla8]-Neurokinin A(4-10) | [bAla8]-Neurokinin A(4-10). Group: Biochemicals. Grades: Purified. CAS No. 122063-01-8. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| (N-Me-Phe7)-Neurokinin B | The MePhe-analog of NKB shows high selectivity for NKB receptors. Synonyms: (MePhe7)neurokinin B; L-α-Aspartyl-L-methionyl-L-histidyl-L-α-aspartyl-L-phenylalanyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide. Grades: 95%. CAS No. 110880-53-0. Molecular formula: C60H81N13O14S2. Mole weight: 1272.49. | |
| (Trp7,β-Ala8)-Neurokinin A (4-10) | (Trp7,β-Ala8)-Neurokinin A (4-10) is a potent and selective NK-3 receptor antagonist demonstrated by antagonizing neurokinin B on the NK-3 receptor in the rat portal vein. Synonyms: R486; L-α-Aspartyl-L-seryl-L-phenylalanyl-L-tryptophyl-β-alanyl-L-leucyl-L-methioninamide; L-Methioninamide, L-α-aspartyl-L-seryl-L-phenylalanyl-L-tryptophyl-β-alanyl-L-leucyl-; H-Asp-Ser-Phe-Trp-β-Ala-Leu-Met-NH2. Grades: ≥95%. CAS No. 132041-95-3. Molecular formula: C41H57N9O10S. Mole weight: 868.01. | |
| 1- (3, 5-Bis (trifluoromethyl) phenyl) ethoxy) -3- (p-tolyl) morpholino) methyl) -5-oxo-4, 5-dihydro-1H-1, 2, 4-triazol-1-yl) phosphonic Acid | 1- (3, 5-Bis (trifluoromethyl) phenyl) ethoxy) -3- (p-tolyl) morpholino) methyl) -5-oxo-4, 5-dihydro-1H-1, 2, 4-triazol-1-yl) phosphonic Acid is an impurity of Fosaprepitant (F727300), which a selective neurokinin-1 (NK-1) receptor antagonist, an antiemetic drug, and a Aprepitant (A729800) prodrug. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C31H31F6N4O6P, Molecular Weight: 700.57. US Biological Life Sciences. | Worldwide |
| 1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(p-tolyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid | 1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(p-tolyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: Fosaprepitant Impurity F; (4-Benzyl-3-{[(2S,3R)-2-{(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-methylphenyl)-4-morpholinyl]methyl}-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid; Phosphonic acid, [3-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-methylphenyl)-4-morpholinyl]methyl]-4,5-dihydro-5-oxo-4-(phenylmethyl)-1H-1,2,4-triazol-1-yl]-. Molecular formula: C31H31F6N4O6P. Mole weight: 700.56. | |
| (1'R,2R,3R)-Defluoro Fosaprepitant Dimeglumine | (1'R,2R,3R)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'R,2R,3R)-Fosaprepitant Dimeglumine | (1'R,2R,3R)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2R,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| (1'R,2R,3S)-Defluoro Fosaprepitant Dimeglumine | (1'R,2R,3S)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'R,2S,3R)-Defluoro Fosaprepitant Dimeglumine | (1'R,2S,3R)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'R,2S,3R)-Fosaprepitant Dimeglumine | (1'R,2S,3R)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Uses: Antiemetics. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2S,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| (1'R,2S,3S)-Defluoro Fosaprepitant Dimeglumine | (1'R,2S,3S)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'R,2S,3S)-Fosaprepitant Dimeglumine | (1'R,2S,3S)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2S,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| (1'S,2R,3R)-Defluoro Fosaprepitant Dimeglumine | (1'S,2R,3R)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'S,2R,3R)-Fosaprepitant Dimeglumine | (1'S,2R,3R)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2R,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| (1'S,2R,3S)-Defluoro Fosaprepitant Dimeglumine | (1'S,2R,3S)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'S,2R,3S)-Fosaprepitant Dimeglumine | (1'S,2R,3S)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2R,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| (1'S,2S,3R)-Defluoro Fosaprepitant Dimeglumine | (1'S,2S,3R)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'S,2S,3R)-Fosaprepitant Dimeglumine | (1'S,2S,3R)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| (1'S,2S,3S)-Defluoro Fosaprepitant Dimeglumine | (1'S,2S,3S)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'S,2S,3S)-Fosaprepitant Dimeglumine | (1'S,2S,3S)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2S,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| [1(S)-Phenylethoxy]-Aprepitant | [1(S)-Phenylethoxy]-Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Group: Biochemicals. Grades: Highly Purified. CAS No. 170902-81-5. Pack Sizes: 1mg, 10mg. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.429999999999. US Biological Life Sciences. | Worldwide |
| 2-[(1S)-1-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-2-(4-fluorophenyl)-2-oxoethoxy]acetic Acid Methyl Ester | 2-[(1S)-1-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-2-(4-fluorophenyl)-2-oxoethoxy]acetic Acid Methyl Ester is an intermediate in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: Intermediate in the preparation of aprepitant metabolites. Synonyms: Methyl [(1S)-1-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-2-(4-fluorophenyl)-2-oxoethoxy]acetate; [(1S)-1-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-2-(4-fluorophenyl)-2-oxoethoxy]acetic Acid Methyl Ester; Acetic acid, 2-[(1S)-1-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-2-(4-fluorophenyl)-2-oxoethoxy]-, methyl ester. Grades: ≥95%. CAS No. 419574-29-1. Molecular formula: C21H17F7O5. Mole weight: 482.34. | |
| 2,2-Bis[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)ethanone | 2,2-Bis[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)ethanone is an intermediate in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: Intermediate in the preparation of aprepitant metabolites. Synonyms: Ethanone, 2,2-bis[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)-; 2,2-Bis{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-1-(4-fluorophenyl)ethan-1-one. Grades: ≥95%. CAS No. 419574-40-6. Molecular formula: C28H19F13O3. Mole weight: 650.43. | |
| 2-Hydroxy-4-(phenylmethyl)-3-morpholinone | 2-Hydroxy-4-(phenylmethyl)-3-morpholinone is an intermediate of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-Morpholinone, 2-hydroxy-4-(phenylmethyl)-; Fosaprepitant Impurity 23; 4-Benzyl-2-hydroxy-3-morpholinone; 2-Hydroxy-4-benzylmorpholin-3-one. Grades: 95%. CAS No. 287930-73-8. Molecular formula: C11H13NO3. Mole weight: 207.23. | |
| 2- (R)-[1- (R)- (3, 5-Bis (trifluoromethyl)phenyl)ethoxy]-3- (S)-fluorophenylmorpholine | 2- (R) -[1- (R) - (3, 5-Bis (trifluoromethyl) phenyl) ethoxy]-3- (S) -fluorophenylmorpholine[Aprepitant-M2] is a metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: A metabolite of aprepitant. Synonyms: Aprepitant-M2; (2R, 3S)-2- ( (R)-1- (3, 5-Bis (trifluoromethyl)phenyl)ethoxy)-3- (4-fluorophenyl)morpholine; Morpholine, 2-[ (1R)-1-[3, 5-bis (trifluoromethyl)phenyl]ethoxy]-3- (4-fluorophenyl)-, (2R,3S)-; (2R- (2aR*), 3a)-2- (1- (3, 5-Bis (trifluoromethyl)phenyl)ethoxy)-3- (4-fluorophenyl)morpholine. Grades: 96%. CAS No. 171338-27-5. Molecular formula: C20H18F7NO2. Mole weight: 437.35. | |
| 2- (R)-[1- (S)- (3, 5-Bis (trifluoromethyl)phenyl)ethoxy]-3- (S)-fluorophenylmorpholine | 2- (R)-[1- (S)- (3, 5-Bis (trifluoromethyl)phenyl)ethoxy]-3- (S)-fluorophenylmorpholine is a metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: A metabolite of aprepitant. Synonyms: Fosaprepitant Impurity 32; Morpholine, 2-[ (1S)-1-[3, 5-bis (trifluoromethyl)phenyl]ethoxy]-3- (4-fluorophenyl)-, (2R,3S)-; [2R-[2aR*), 3a]-2-[1-[3, 5-Bis (trifluoromethyl)phenyl]ethoxy]-3- (4-fluorophenyl)morpholine. Grades: 95%. CAS No. 170729-79-0. Molecular formula: C20H18F7NO2. Mole weight: 437.35. | |
| (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine | (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine is an intermediate in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: Intermediate in the preparation of enantiomerically pure aprepitant diastereomers and derivatives. Synonyms: Aprepitant dehydro dealkyl; Desfluro Aprepitant; 2H-1,4-Oxazine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-, (2R)-; (R)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine; 2alpha-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine; Aprepitant Impurity 6. Grades: ≥95%. CAS No. 380499-07-0. Molecular formula: C20H16F7NO2. Mole weight: 435.33. | |
| (2R,3R,1S)-Aprepitant | (2R,3R,1S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1242175-34-3. Pack Sizes: 1mg. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.429999999999. US Biological Life Sciences. | Worldwide |
| (2R,3R)-2-benzhydryl-N-benzylquinuclidin-3-amine-(D)-10-camphorsulfonate | (2R,3R)-2-benzhydryl-N-benzylquinuclidin-3-amine-(D)-10-camphorsulfonate is an impurity of Maropitant. Maropitant is a neurokinin (NK1) receptor antagonist. Synonyms: Maropitant Impurity 1. Grades: 99% by HPLC. CAS No. 2243127-08-2. Molecular formula: C37H46N2O4S. Mole weight: 614.85. | |
| (2S,3R,1R)-Aprepitant | (2S,3R,1R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1185502-97-9. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.429999999999. US Biological Life Sciences. | Worldwide |
| (2S,3S,1R)-Aprepitant | (2S,3S,1R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. (2S,3S,1R)-Aprepitant is also a useful synthetic intermediate in the synthesis of morpholine tachykinin receptor antagonist prodrugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 172822-28-5. Pack Sizes: 1mg. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.429999999999. US Biological Life Sciences. | Worldwide |
| (2S,3S)-2-benzhydryl-N-benzylquinuclidin-3-amine-(1R)-10-camphorsulfonate | (2S,3S)-2-benzhydryl-N-benzylquinuclidin-3-amine-(1R)-10-camphorsulfonate is an impurity of Maropitant. Maropitant is a neurokinin (NK1) receptor antagonist. Synonyms: Maropitant Impurity A; Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1R,4S)-, compd. with (2S,3S)-2-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine (1:1). Grades: 99% by HPLC. CAS No. 862543-55-3. Molecular formula: C37H46N2O4S. Mole weight: 614.85. | |
| 3-Des-(4-fluorophenyl) 3-(4-Fluorobiphen-3-yl) Aprepitant | 3-Des-(4-fluorophenyl) 3-(4-Fluorobiphen-3-yl) is a derivative of Aprepitant, which is a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 5-{[(2R,3S)-2-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-(3-fluoro-4-biphenylyl)-4-morpholinyl]methyl}-2,4-dihydro-3H-1,2,4-triazol-3-one; 3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(3-fluoro[1,1'-biphenyl]-4-yl)-4-morpholinyl]methyl]-2,4-dihydro-. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| 4-Benzyl-2,3-morpholinedione | 4-Benzyl-2,3-morpholinedione is an intermediate of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 4-(Phenylmethyl)-2,3-morpholinedione; 2,3-Morpholinedione, 4-(phenylmethyl)-. Grades: ≥95%. CAS No. 110843-90-8. Molecular formula: C11H11NO3. Mole weight: 205.21. | |
| (5R,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone | (5R,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone is a diastereomeric byproduct in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: A diastereomeric byproduct formed during the synthesis of aprepitant metabolites. Synonyms: 3-Morpholinone, 6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5R,6R)-; Aprepitant M2 Metabolite 5-Epimer. Grades: ≥95%. CAS No. 419574-33-7. Molecular formula: C20H16F7NO3. Mole weight: 451.33. | |
| (5R,6S)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone | (5R,6S)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone is an active metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-Morpholinone, 6-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5R,6S)-; ent-Aprepitant-M3; Aprepitant M3 Metabolite (1S,5R,6S)-Isomer. Molecular formula: C20H16F7NO3. Mole weight: 451.33. | |
| Acetylaszonalenin | Acetylaszonalenin is a fungal metabolite that has been found in A. flavipes. It acts as an antagonist of neurokinin-1 (NK1) receptor. Synonyms: 2-acetoxy-n,n,n-trimethylethanaminium iodide; (+)-Acetylaszonalenin; (5aS,13aR,14aS)-5-acetyl-14a-(1,1-dimethyl-2-propen-1-yl)-5a,13a,14,14a-tetrahydro-indolo[3',2':4,5]pyrrolo[2,1-c][1,4]benzodiazepine-7,13(5H,12H)-dione; LL-S490β; Antibiotic LL-S490&beta. Grades: ≥95%. CAS No. 42230-55-7. Molecular formula: C25H25N3O3. Mole weight: 415.48. | |
| Aprepitant | Aprepitant an antiemetic and antagonist of the neurokinin-1 (NK1) receptor (Ki = 3nM; IC50 = 0.09nM for the human receptor).It is selective for NK1 over NK3 receptors (Ki = 454.1nM for human NK3). In vivo, aprepitant (1mg/Kg) prevents plasma extravasation into the esophagus of guinea pigs induced by substance P. It also reduces NK1-agonist-induced foot tapping in gerbils. Formulations containing aprepitant have been used to prevent chemotherapy-induced nausea and vomiting. Group: Biochemicals. Alternative Names: 5-[[ (2R, 3S) -2-[ (1R) -1-[3, 5-Bis (trifluoromethyl) phenyl]ethoxy]-3- (4-fluorophenyl) -4-morpholinyl]methyl]-1, 2-dihydro-3H-1, 2, 4-triazol-3-one; Emend; L 754030; MK-869; ONO-7436. Grades: Highly Purified. CAS No. 170729-80-3. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.43. US Biological Life Sciences. | Worldwide |
| Aprepitant EP Impurity B | Aprepitant EP Impurity B is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-3-yl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one. CAS No. 2348441-62-1. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| Aprepitant EP Impurity C | Aprepitant EP Impurity C is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-4-yl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one; 4-Defluoro-4-(p-fluorophenyl)aprepitant. CAS No. 2348441-63-2. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| Aprepitant Impurity 10 HCl | Aprepitant Impurity 10 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: (2R,3R)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride; 1447693-83-5. CAS No. 1447693-83-5. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
| Aprepitant Impurity 14 | Aprepitant Impurity 14 is a derivative of Aprepitant, which is a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-Des-(4-fluorophenyl) 3-(R)-(4'-Fluorobiphen-4-yl) Aprepitant. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| Aprepitant Impurity 8 HCl | Aprepitant Impurity 8 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: Fosaprepitant Morpholine Hydrochloride; (2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride. CAS No. 1333998-27-8. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
| Aprepitant Impurity B HCl | Aprepitant Impurity B HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C27H24F7NO2.HCl. Mole weight: 563.93. | |
| Aprepitant-M3 Metabolite | Aprepitant-M3 Metabolite is a metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: An active metabolite of aprepitant. Synonyms: (5S,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone; Aprepitant-M3; 3-Morpholinone, 6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5S,6R)-. Grades: ≥95%. CAS No. 419574-04-2. Molecular formula: C20H16F7NO3. Mole weight: 451.33. | |
| Benzomalvin A | It is produced by the strain of Penicillum sp. Benzomalvin A was isolated as an active inhibitor of substance P binding to mammalian neurokinin NK1 receptors. Benzomalvin A is a fungal metabolite produced by Penicillium. It inhibits yeast α-glucosidase in vitro with IC50 of 383.2 μM. Benzomalvin A also acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P to guinea pig, rat, and human NK1 (Kis = 12, 42, and 43 μM, respectively). Synonyms: (-)-Benzomalvin A; Enzomalvin-A. Grades: ≥95%. CAS No. 157047-96-6. Molecular formula: C24H19N3O2. Mole weight: 381.43. | |
| Benzomalvin B | It is produced by the strain of Penicillum sp. Benzomalvin B was isolated as an active inhibitor of substance P binding to mammalian neurokinin NK1 receptors. Benzomalvin B is a fungal metabolite produced by Penicillium. It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P by 24% in vitro when used at a concentration of 100 μg/ml. Synonyms: (-)-Benzomalvin B; Enzomalvin-B. Grades: ≥95%. CAS No. 157047-97-7. Molecular formula: C24H17N3O2. Mole weight: 379.41. | |
| Benzomalvin C | Benzomalvin C is produced by the strain of Penicillum sp. It is a neurokinin NK1 receptor antagonist and IDO inhibitor. Synonyms: 6'-methyl-3-phenyl-13'h-spiro[oxirane-2,7'-quinazolino[3,2-a][1,4]benzodiazepine]-5',13'(6'h)-dione; GK3542; GK 3542; GK-3542; benzomalvin C. Grades: >98%. CAS No. 157047-98-8. Molecular formula: C24H17N3O3. Mole weight: 395.41. | |
| Boc-3,4-dichloro-D-phenylalanine | Boc-3,4-dichloro-D-phenylalanine is used to prepare fluorinated β-aminoacyl 1,2,4-triazolo[4,3-a]piperazine amides as dipeptidyl peptidase IV inhibitors and antidiabetic agents. It is also used in the synthesis of N-[(R,R)-(E)-1-(3,4-dichlorobenzyl)-3-(2-oxoazepan-3-yl)carbamoyl]allyl-N-methyl-3,5-bis(trifluoromethyl)benzamide as a potent and orally active dual neurokinin NK1/NK2 receptor antagonist. Synonyms: Boc-D-Phe(3,4-DiCl)-OH; Boc-D-Phe(3,4-Cl2)-OH; (R)-Boc-2-amino-3-(3,4-dichlorophenyl)propionic acid; Boc-D-Phe(3,4-Cl2)-OH; (R)-2-((tert-Butoxycarbonyl)amino)-3-(3,4-dichlorophenyl)propanoic acid; D-Phenylalanine, 3,4-dichloro-N-[(1,1-dimethylethoxy)carbonyl]-; Boc-D-3,4-Dichlorophenylalanine; AK162594; N-BOC-3,4-DICHLORO-D-PHENYLALANINE. Grades: ≥ 98% (HPLC). CAS No. 114873-13-1. Molecular formula: C14H17Cl2NO4. Mole weight: 334.20. | |
| Casopitant | Casopitant mesylate is the mesylate salt of a centrally-acting neurokinin 1 (NK1) receptor antagonist with antidepressant and antiemetic activities. Casopitant competitively binds to and blocks the activity of the NK1 receptor, thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in antiemetic effects. SP is found in neurons of vagal afferent fibers innervating the brain-stem nucleus tractus solitarii and the area postrema, which contains the chemoreceptor trigger zone (CTZ), and may be elevated in response to chemotherapy. The NK1 receptor is a G-protein receptor coupled to the inositol phosphate signal-transduction pathway and is found in both the nucleus tractus solitarii and the area postrema. Uses: Antiemetics. Synonyms: GW679769; GW 679769; GW-679769; Zunrisa; Rezonic; 4-(4-Acetylpiperazin-1-yl)-N-{1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide. CAS No. 414910-27-3. Molecular formula: C30H35F7N4O2. Mole weight: 616.62. | |
| Casopitant mesylate | Casopitant mesylate (GW679769B) is a potent, selective, brain permeable and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant mesylate is a second in the class of antiemetics that acts to antagonise the emetogenic effect of Substance P (HY-P0201). Casopitant mesylate is also a substrate and a weak-to-moderate inhibitor of CYP3A4. Casopitant mesylate can be used for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW679769B. CAS No. 414910-30-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14405A. | |
| Casopitant Mesylate | Casopitant Mesylate is a potent, selective and orally active neurokinin 1 (NK1) receptor antagonist binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in antiemetic effects. Uses: Active tachykinin nk1 receptor antagonist. Synonyms: (2R,4S)-4-(4-acetylpiperazin-1-yl)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide;methanesulfonic acid. Grades: ≥98%. CAS No. 414910-30-8. Molecular formula: C31H39F7N4O5S. Mole weight: 712.72. | |
| Clevidipine butyrate | 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-Pyridinedicarboxylic acid methyl (1-oxobutoxy). substance P antagonists (SPA). It mediates its effect by acting on neurokinin 1 receptor. CAS No. 167221-71-8. Product ID: 8-04645. Molecular formula: C21H23NO6Cl2. Mole weight: 456.32. Purity: 0.99. |  |
| CP-100263 Dihydrochloride Hydrate | CP-100263 is an NK-1 neurokinin receptor antagonist as testosterone replacement therapy. Group: Biochemicals. Alternative Names: (2R,3R)-N-[(2-methoxyphenyl)methyl]-2-phenyl-3-piperidinamine Dihydrochloride Hydrate; (2R-cis)-N-[(2-methoxyphenyl)methyl]-2-phenyl-3-piperidinamine Dihydrochloride Hydrate; (-)-CP 99994 Dihydrochloride Hydrate; CP 100263 Dihydrochloride Hydrate. Grades: Highly Purified. CAS No. 872726-33-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'R)-Aprepitant | Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'R)-Aprepitant is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: (2S,3R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. CAS No. 1185503-48-3. Molecular formula: C20H18F7NO7. Mole weight: 517.35. | |
| Desfluoro Fosaprepitant | Desfluoro Fosaprepitant is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (3-{[(2R,3S)-2-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-phenyl-4-morpholinyl]methyl}-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid; Phosphonic acid, [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-phenyl-4-morpholinyl]methyl]-4,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-. Molecular formula: C23H23F6N4O6P. Mole weight: 596.42. | |
| D-Lysine lactam | D-Lysine lactam has been used in the synthesis of a chiral antibiotic synthetic intermediate, as well as in the stereoselective synthesis of neurokinin (NK) receptor antagonists. Synonyms: D-2-aminohexano-6-lactam; (R)-3-Amino-2-azepanone; D-alpha-amino-epsilon-caprolactam; (r)-3-Aminoazepan-2-one; (+)-α-Amino-ε-caprolactam. Grades: 97.0 % (GC). CAS No. 28957-33-7. Molecular formula: C6H12N2O. Mole weight: 128.17. | |
| Eprazinone dihydrochloride | Eprazinone dihydrochloride is a gent with mucolytic, secretolytic, antitussive, and bronchial antispasmodic properties. Eprazinone dihydrochloride is a neurokinin 1 receptor (NK1R) ligand. Eprazinone dihydrochloride has the potential for chronic bronchitis treatment that improved pulmonary function and arterial partial pressure of oxygen [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10402-53-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B2078A. | |
| Eprazinone dihydroChloride | Eprazinone dihydrochloride is a drug with proposed mucolytic, secretolytic, and bronchial antispasmodic properties. Eprazinone dihydrochloride is a neurokinin 1 receptor (NK1R) ligand. It has the potential for chronic bronchitis treatment that improved pulmonary function and arterial partial pressure of oxygen. Uses: Expectorants. Synonyms: 3-[4-(β-Ethoxyphenethyl)-1-piperazinyl]-2-methylpropiophenone, Dihydrochloride; 746CE; Eftapan; Eprazinone Hydrochloride; Mucitux; NSC 317935; Resplen. Grades: >98%. CAS No. 10402-53-6. Molecular formula: C24H34Cl2N2O2. Mole weight: 453.44. | |
| Fezolinetant | Fezolinetant is a neurokinin 3 receptor (NK3R) antagonist used to treat sex hormone-related diseases. Synonyms: Fezolinetant; 1629229-37-3; ESN364ESN-364; UNII-83VNE45KXX. Grades: ≥98% by HPLC. CAS No. 1629229-37-3. Molecular formula: C16H15FN6OS. Mole weight: 358.4. | |
| Fosaprepitant | Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antahonist. It is an antiemetic drug, which is a Aprepitant prodrug. Uses: Antiemetics. Synonyms: P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonic Acid; L 758298; [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)mor. Grades: > 95%. CAS No. 172673-20-0. Molecular formula: C23H22F7N4O6P. Mole weight: 614.42. | |
| Fosaprepitant Dibenzyl Ester | Fosaprepitant Dibenzyl Ester is a reactant in the synthesis of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-phosphonic Acid bis(Phenylmethyl) Ester; Dibenzyl Fosaprepitant; Fosaprepitant Impurity 16; Phosphonic acid, P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-, bis(phenylmethyl) ester; 2-Bis(phenylmethoxy)phosphoryl-5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-4H-1,2,4-triazol-3-one. Grades: >95%. CAS No. 265121-01-5. Molecular formula: C37H34F7N4O6P. Mole weight: 794.65. | |
| Fosaprepitant Dimeglumine | Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antahonist. Fosaprepitant is an antiemetic drug, a Aprepitant prodrug. Group: Biochemicals. Alternative Names: [3-[[ (2R, 3S) -2-[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]-3- (4-fluorophenyl) -4-morpholinyl]methyl]-2, 5-dihydro-5-oxo-1H-1, 2, 4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; MK 0517. Grades: Highly Purified. CAS No. 265121-04-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Fosaprepitant Morpholine | Fosaprepitant Morpholine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: Fosaprepitant Impurity 27; Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3S)-; Aprepitant M2 Metabolite (1R,2S,3S)-Isomer; Aprepitant impurity 20; (2S,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. Grades: ≥95%. CAS No. 170902-80-4. Molecular formula: C20H18F7NO2. Mole weight: 437.35. | |
Our database is helping our users find suppliers everyday.
