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| Product | Description | |
|---|---|---|
| Neurotensin | ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Neurotensin | Neurotensin, a gut tridecapeptide, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinity neurotensin receptors ( NTR ). Uses: Scientific research. Group: Peptides. CAS No. 39379-15-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0234. |  |
| Neurotensin | Neurotensin is a neuropeptide found in the central nervous system (CNS) and the gastrointestinal tract. It acts as a neuromodulator to several neurotransmitter systems including dopaminergic, sertonergic, GABAergic, glutamatergic, and cholinergic systems. CAS No. 39379-15-2. |  |
| Neurotensin | Neurotensin is a selective, non-competitive NMDA receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 39379-15-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C78H121N21O20, Molecular Weight: 1672.94. US Biological Life Sciences. |  Worldwide |
| Neurotensin | Neurotensin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NEUROTENSIN, BOVINE;NEUROTENSIN (HUMAN, BOVINE, CANINE);NEUROTENSIN (HUMAN, BOVINE, CANINE) 2ACOH 6H2O;NEUROTENSIN (1-13);NEUROTENSIN;PYR-LYENKPRRPYIL;PYR-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU;PYR-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU. Product Category: Heterocyclic Organic Compound. CAS No. 39379-15-2. Molecular formula: C78H121N21O20. Mole weight: 1672.92. Purity: 0.96. IUPACName: 2-[[2-[[2-[[1-[2-[[2-[[1-[6-amino-2-[[4-amino-2-[[4-carboxy-2-[[3-(4-hydroxyphenyl)-2-[[4-methyl-2-[(5-oxopyrrolidine-2-carbonyl)amino]pentanoyl]amino]propanoyl]amino]butanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomet. Density: 1.46g/cm³. Product ID: ACM39379152. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Neurotensin (1-8) | Neurotensin (1-8). Synonyms: Pglu-leu-tyr-glu-asn-lys-pro-arg; L-Pyr-L-Leu-L-Tyr-L-Glu-L-Asn-L-Lys-L-Pro-L-Arg; 5-oxo-L-prolyl-L-leucyl-L-tyrosyl-L-alpha-glutamyl-L-asparaginyl-L-lysyl-L-prolyl-L-arginine. CAS No. 80887-44-1. Molecular formula: C46H71N13O14. Mole weight: 1030.13. | |
| Neurotensin (8-13) | Neurotensin (8-13), the smallest active fragment of neurotensin, results in a decrease in cell-surface NT1 receptors (NTR1) density. Synonyms: H-Arg-Arg-Pro-Tyr-Ile-Leu-OH; L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine; NT(8-13); Neurotensin Fragment 8-13; N5-(Diaminomethylene)-L-ornithyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine. Grade: >97% by HPLC. CAS No. 60482-95-3. Molecular formula: C38H64N12O8. Mole weight: 816.99. | |
| Neurotensin(8-13) | Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. Uses: Scientific research. Group: Peptides. CAS No. 60482-95-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0251. | |
| Neurotensin - CAS 39379-15-2 | Potent hypothalamic peptide neurotransmitter. Group: Fluorescence/luminescence spectroscopy. | |
| Neurotensin (cattle) | Neurotensin, a gut tridecapeptide with many central and peripheral functions, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinityneurotensin receptors(NTR). Neurotensin also can be used as neuromodulator of dopamine transmission and exerts potent hypothermic and analgesic effects. Synonyms: H-Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH; L-pyroglutamyl-L-leucyl-L-tyrosyl-L-alpha-glutamyl-L-asparagyl-L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine; Neurotensin 1-13; Neurotensin (ox); 5-Oxo-L-prolyl-L-leucyl-L-tyrosyl-L-α-glutamyl-L-asparaginyl-L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine; L-Leucine, 5-oxo-L-prolyl-L-leucyl-L-tyrosyl-L-α-glutamyl-L-asparaginyl-L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-; Bovine neurotensin; Canine neurotensin; Mouse neurotensin; Neurotensin (bovine hypothalamus); Neurotensin (dog); Neurotensin (rat); Ox neurotensin. Grade: ≥97% by HPLC. CAS No. 55508-42-4. Molecular formula: C78H121N21O20. Mole weight: 1672.92. | |
| Neurotensin Fragment 8-13 acetate salt | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Neurotensin TFA salt | Neurotensin TFA salt, a gut tridecapeptide with many central and peripheral functions, is a potent cellular mitogen with a high-affinity neurotensin receptor (NTR) for various colorectal and pancreatic cancers. Synonyms: Neurotensin trifluoroacetate salt; H-Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH.TFA; L-pyroglutamyl-L-leucyl-L-tyrosyl-L-alpha-glutamyl-L-asparagyl-L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine trifluoroacetic acid. Molecular formula: C78H121N21O20.xC2HF3O2. Mole weight: 1672.92 (free base). | |
| (3,5-Dibr-tyr11)-neurotensin | (3,5-Dibr-tyr11)-neurotensin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: [3,5-diBr-Tyr11]-Neurotensin, N3010_SIGMA, 112898-47-2. Product Category: Heterocyclic Organic Compound. CAS No. 112898-47-2. Molecular formula: C78H119Br2N21O20. Mole weight: 1830.72. Purity: 0.96. IUPACName: 2-[[2-[[2-[[1-[2-[[2-[[1-[6-amino-2-[[4-amino-2-[[4-carboxy-2-[[3-(4-hydroxyphenyl)-2-[[4-methyl-2-[(5-oxopyrrolidine-2-carbonyl)amino]pentanoyl]amino]propanoyl]amino]butanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomet. Canonical SMILES: CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CC(=C(C(=C1)Br)O)Br)NC(=O)C2CCCN2C(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CC(C)C)NC(=O)C5CCC(=O)N5. Product ID: ACM112898472. Alfa Chemistry ISO 9001:2015 Certified. | |
| (Boc-Lys9)-Neurotensin (9-13)-methyl ester | (Boc-Lys9)-Neurotensin (9-13)-methyl ester. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| [D-Trp11]-Neurotensin | [D-Trp11]-Neurotensin is an analogue of Neurotensin (NT). It is a selective antagonist of NT in perfused rat hearts but behaves as a full agonist in guinea pig atria and rat stomach strips. [D-Trp11]-Neurotensin can also inhibit NT-induced hypotension. CAS No. 73634-68-1. Molecular formula: C80H122N22O19. Mole weight: 1695.96. | |
| [Gln4]-Neurotensin | Neurotensin induces contractions in smooth muscle cells, playing a role in regulating digestive activity in vitro and in vivo. Synonyms: 4-Gln-neurotensin; H-Pyr-Leu-Tyr-Gln-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH. Grade: 98%. CAS No. 61445-54-3. Molecular formula: C78H122N22O19. Mole weight: 1671.9. | |
| (Lys8,Lys9)-Neurotensin (8-13) | [Lys8, Lys9]-Neurotensin (8-13) is a neurotensin analog. It exerts analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, with Ki values of 0.33 nM and 0.95 nM for hNTS1 and hNTS2 receptors, respectively. Synonyms: JMV438. CAS No. 139026-64-5. Molecular formula: C38H64N8O8. Mole weight: 760.96. | |
| 3-Chloro-4-piperazinobenzoic Acid | 3-Chloro-4-piperazinobenzoic Acid acts as a reagent in the preparation of piperazinyl quinazolines and related compounds as agonist of neurotensin receptor 1. Group: Biochemicals. Grades: Highly Purified. CAS No. 1197193-06-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H13ClN2O2, Molecular Weight: 240.69. US Biological Life Sciences. | Worldwide |
| AC-ARG-ARG-PRO-TYR-ILE-LEU-OH | AC-ARG-ARG-PRO-TYR-ILE-LEU-OH. Synonyms: Acetylneurotensin (8-13); N-Acetyl-neurotensin-(8-13); L-Leucine, N-(N-(N-(1-(N2-(N2-acetyl-L-arginyl)-L-arginyl)-L-prolyl)-L-tyrosyl)-L-isoleucyl)-. CAS No. 74853-69-3. Molecular formula: C40H66N12O9. Mole weight: 859.03. | |
| Dilept | Dilept is an antagonist of neurotensin (NT) and dopamine (DA) receptor used to mitigate positive and negative symptoms of schizophrenia. Uses: Schizophrenia treatment. Synonyms: N-caproyl-l-prolyl-l-tyrosine methyl ester; methyl (2S)-2-[[(2S)-1-hexanoylpyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoate. Grade: 99%. CAS No. 200954-39-8. Molecular formula: C21H30N2O5. Mole weight: 390.47. | |
| Fmoc-N-Me-Arg(Pbf)-OH | Fmoc-N-Me-Arg(Pbf)-OH is an amino acid derivative containing a guanidinium protecting group on the arginine side chain. Fmoc-N-Me-Arg(Pbf)-OH is used in the synthesis of neurotensin-derived NTS1 ligands for PET imaging [1]. Uses: Scientific research. Group: Peptides. CAS No. 913733-27-4. Pack Sizes: 500 mg; 1 g. Product ID: HY-137002. | |
| Glyoxylic Acid (50% aqueous solution) | Glyoxylic Acid is used as a reagent in the synthesis of N-{[6-chloro-4- (2, 6-dimethoxyphenyl) quinazolin-2-yl]carbonyl}-L-leucine, a novel nonpeptide chemotype selective for neurotensin receptor 2. Also used as a reagent in the synthesis of elemonic acid derivatives as Pin1 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 298-12-4. Pack Sizes: 1g, 10g. Molecular Formula: C2H2O3. US Biological Life Sciences. | Worldwide |
| Glyoxylic Acid Hydrate-13C2 | Glyoxylic Acid Hydrate-13C2 is the labelled hydrated analog of Glyoxylic Acid (G754995) which is used as a reagent in the synthesis of N-{[6-chloro-4- (2, 6-dimethoxyphenyl) quinazolin-2-yl]carbonyl}-L-leucine, a novel nonpeptide chemotype selective for neurotensin receptor 2. Also used as a reagent in the synthesis of elemonic acid derivatives as Pin1 inhibitors. Glyoxylic Acid-13C2 was used in the synthesis of carbon labelled 6-N-carboxymethyllysine (CML) which is the most used marker for advanced glycation endproducts in food analysis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: 3C2H4O4, Molecular Weight: 94.04. US Biological Life Sciences. | Worldwide |
| JMV 390-1 | JMV 390-1 has been found to be an inhibitor of the major neurotensin and neuromedin N degrading enzymes and could probably show analgesic activities. Synonyms: Jmv-390-1; Jmv390-1; N-[(2R)-4-Hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-L-isoleucyl-L-leucine. Grade: ≥95% by HPLC. CAS No. 148473-36-3. Molecular formula: C23H35N3O6. Mole weight: 449.54. | |
| JMV 449 | JMV 449 could be a neurotensin receptor agonist peptide and has been found to show hypothermic and analgesic activities in the mouse. Synonyms: JMV-449; JMV449; (S)-1-de-L-lysine-2-[N2-(2,6-diaminohexyl)-L-lysine]-neuromedin N (pig spinal cord); H-Lysy(CH2NH)Lys-Pro-Tyr-Ile-Leu-OH. Grade: ≥95% by HPLC. CAS No. 139026-66-7. Molecular formula: C38H66N8O7. Mole weight: 746.96. | |
| JMV 449 acetate | JMV 449 acetate is a potent neurotensin receptor agonist. JMV 449 acetate shows an IC 50 of 0.15 nM for inhibition of 125 I-neurotensin binding to neonatal mouse brain and an EC 50 of 1.9 nM in contracting the guinea-pig ileum. JMV 449 acetate has highly potent and long-lasting hypothermic and analgesic effects in the mouse [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 141863-45-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1256C. | |
| Kinetensin | Kinetensin (human) is an endogenous neurotensin-like peptide originally isolated from pepsin-treated human plasma. It increases vascular permeability and releases histamine from rat mast cells. It induces histamine release from rat peritoneal mast cells with ED50 value of 10 mM in vitro. Synonyms: Kinetensin (human); Neurotensin-related peptide; H-Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu-OH; L-isoleucyl-L-alanyl-L-arginyl-L-arginyl-L-histidyl-L-prolyl-L-tyrosyl-L-phenylalanyl-L-leucine. Grade: ≥95%. CAS No. 103131-69-7. Molecular formula: C56H85N17O11. Mole weight: 1172.38. | |
| L-Cycloserine | L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase ( GABA-t ) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-Cycloserine; (S)-4-Amino-3-isoxazolidone. CAS No. 339-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1122. | |
| Levocabastine hydrochloride | Levocabastine (R 50547) hydrochloride is a potent and selective histamine H1-receptor antagonist. Levocabastine hydrochloride is also a selective, high affinity neurotensin receptor subtype 2 (NTR2) antagonist, with a K i of 17 nM for mNTR2. Levocabastine hydrochloride can act as a VLA-4 antagonist, interferes with conjunctival eosinophil infiltration in allergic conjunctivitis (AC) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 50547 hydrochloride. CAS No. 79547-78-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-14277A. | |
| neurolysin | No absolute requirement for a prolyl bond: the enzyme acts on some peptides, such as dynorphin 1-8, that do not contain proline, and does not act on some others that do. In peptidase family M3 (thimet oligopeptidase family). Group: Enzymes. Synonyms: neurotensin endopeptidase; endopeptidase 24.16; endo-oligopeptidase B (proline-endopeptidase). Enzyme Commission Number: EC 3.4.24.16. CAS No. 149371-24-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4297; neurolysin; EC 3.4.24.16; 149371-24-4; neurotensin endopeptidase; endopeptidase 24.16; endo-oligopeptidase B (proline-endopeptidase). Cat No: EXWM-4297. |  |
| Neuromedin N (swine spinal cord) | Neuromedin N is a potent modulator of dopamine D2 receptor agonist which binds in rat neostriatal membranes. It produced a significant concentration-related increase in the Kd values of [3H]L-(-)-N-propylnorapomorphine binding sites in the concentration range of 1-10 nM. It is endogenous neurotensin-like neuropeptide isolated from porcine spinal cord. It binds to neurotensin receptors. It regulates guinea pig intestinal smooth muscle contraction and produces hypotension in rats. It also induces hypothermia following central administration in rats in vivo. Synonyms: L-Leucine, L-lysyl-L-isoleucyl-L-prolyl-L-tyrosyl-L-isoleucyl-; L-Lysyl-L-isoleucyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine; Neuromedin N (pig spinal cord); Canine neuromedin N; Mouse neuromedin N; Neuromedin N (dog); Neuromedin N (human); Neuromedin N (ox); Neuromedin N (rat); Porcine neuromedin N; Neuromedin N (rat, mouse, porcine, canine); H-Lys-Ile-Pro-Tyr-Ile-Leu-OH; L-Lys-L-Ile-L-Pro-L-Tyr-L-Ile-L-Leu-OH; Lysyl-isoleucyl-prolyl-tyrosyl-isoleucyl-leucine. Grade: >98%. CAS No. 92169-45-4. Molecular formula: C38H63N7O8. Mole weight: 745.95. | |
| NODAGA-PEG-NT-XII | NODAGA-PEG-NT-XII is a neurotensin analog that can be used as a metal chelator for tumor imaging and drug delivery study. Mole weight: 1436.49. | |
| NTRC-824 | NTRC-824 (Compound 5) is a potent, selective and neurotensin-like nonpeptide neurotensin receptor type 2 (NTS2) antagonist with an IC 50 of 38 nM and a K i of 202 nM. NTRC-824 is >150-fold selectivity for NTS2 over NTS1 (K i >30 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1623002-61-8. Pack Sizes: 1 mg. Product ID: HY-12436. | |
| RP-66453 | RP-66453 is a secondary peptide metabolite produced by Streptomyces sp. A 9738. It can selectively bind to neurotensin receptor. Synonyms: RP 66453; RP66453. Molecular formula: C33H36N4O8. Mole weight: 616.7. | |
| SR 142948 | SR 142948 is an orally active and selective non-peptide neurotensin receptor ( NT ) antagonist with IC 50 s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC50 of 3.9 nM. SR 142948 blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 shows blood-brain permeability and can be used in study of psychiatric disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 184162-64-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107664. | |
| VIP Antagonist | VIP antagonist, a hybrid of neurotensin (6-11) and VIP (7-28), is a competitive antagonist of VIP-binding to glial cells. In rats with reduced masculine potency, it significantly inhibits VIP-stimulated sexual behavior. It antagonizes VIP receptors on non-small cell lung cancer cells, thereby inhibiting tumor growth in vivo and in vitro. Synonyms: [Lys1,Pro2,5,Arg3,4,Tyr6]VIP, human, porcine, rat, ovine; H-Lys-Pro-Arg-Arg-Pro-Tyr-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2; L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-threonyl-L-alpha-aspartyl-L-asparagyl-L-tyrosyl-L-threonyl-L-arginyl-L-leucyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-valyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-asparagyl-L-seryl-L-isoleucyl-L-leucyl-L-asparaginamide; [Lys1,Pro2,5,Arg3,4,Tyr6]-Vasoactive Intestinal Peptide human, porcine, rat. Grade: 95%. CAS No. 125093-93-8. Molecular formula: C154H257N49O40S. Mole weight: 3467.06. | |
| Xenopsin | Xenopsin, the neurotensin-like octapeptide from Xenopusskin at the carboxyl terminus of its precursor, shows sequence homology to mammalian neurotensin and shares a number of its biological properties. Synonyms: H-Pyr-Gly-Lys-Arg-Pro-Trp-Ile-Leu-OH; 5-oxo-L-prolylglycyl-L-lysyl-L-arginyl-L-prolyl-L-tryptophyl-L-isoleucyl-L-leucine. Grade: >98%. CAS No. 51827-01-1. Molecular formula: C47H73N13O10. Mole weight: 980.16. | |
| Xenopsin 2TFA | Xenopsin 2TFA is a neurotensin-like octapeptide previously isolated from amphibian skin. Synonyms: H-Pyr-Gly-Lys-Arg-Pro-Trp-Ile-Leu-OH.2TFA; L-pyroglutamyl-glycyl-L-lysyl-L-arginyl-L-prolyl-L-tryptophyl-L-isoleucyl-L-leucine trifluoroacetic acid; 5-Oxo-L-prolylglycyl-L-lysyl-L-arginyl-L-prolyl-L-tryptophyl-L-isoleucyl-L-leucine trifluoroacetate; Xenopsin trifluoroacetate; L-Leucine, N-[N-[N-[1-[N2-[N2-[N-(5-oxo-L-prolyl)glycyl]-L-lysyl]-L-arginyl]-L-prolyl]-L-tryptophyl]-L-isoleucyl]-, trifluoroacetate (1:2); Xenopsin (Xenopus amieti) trifluoroacetate. Grade: ≥95%. Molecular formula: C51H75F6N13O14. Mole weight: 1208.23. | |
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