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Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Nicotinic acid; Vitamin B3. CAS No. 59-67-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0143.
Niacinamide
Niacinamide. CAS No: 98-92-0
Sarchem Laboratories New Jersey NJ
Niacinamide
Niacinamide (Nicotinamide) is vitamin B3, an essential nutrient. It provides both nutritional and topical benefits. As a skin care active, niacinamide can improve the appearance of hyperpigmented skin, reduce redness, fine lines and wrinkles, smooth skin texture and enhance skin barrier properties. Uses: Niacinamide is suitable for serums, masks, facial cleansers, lotions, astringents, creams, moisturizers, conditioners, toners, and foundations. Recommended for skin lightening, anti-wrinkle, pore size reduction, anti-inflammatory, anti-acne, and skin barrier improvement. Group: Skin Lightening, Anti-inflammation, Anti-wrinkle, Anti-aging. Alternative Names: Nicotinamide, Vitamin B3. CAS No. 98-92-0. Pack Sizes: 20kg, 3x20kg, 1kg. Categories: 3-pyridinecarboxamide; nicotinic acid amide.
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Niacinamide
Pharmacopeia & Metrological Institutes Standards. Uses: For analytical and research use. Group: Reagents. CAS No. 98-92-0. Pack Sizes: 500MG.
Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver , fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term niacin has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor). Group: Biochemicals. Alternative Names: Nicotinic acid; Vitamin B3; 3-Pyridinecarboxylic Acid; 3-Carboxylpyridine; 3-Carboxypyridine; Akotin; Apelagrin; Niacin; Niacor; Niaspan; Nicacid; Pelonin; Vitamin B5; Wampocap; β-Pyridinecarboxylic Acid. Grades: Cell Culture Grade. CAS No. 59-67-6. Pack Sizes: 100g, 500g, 1Kg. Molecular Formula: C6H5NO2, Molecular Weight: 123.11. US Biological Life Sciences.
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Niacin (standard)
Niacin (Standard) is the analytical standard of Niacin. This product is intended for research and analytical applications. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Nicotinic acid (standard); Vitamin B3 (standard). CAS No. 59-67-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0143R.
Niacin USP (Granular)
Niacin USP (Granular).
CA, FL & NJ
Vitamin B3 Niacinamide Bp
Vitamin B3 Niacinamide Bp - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Vitamin B3-Niacinamide USP
Vitamin B3-Niacinamide USP.
CA, FL & NJ
Vitamin B3 Niacin Bp
Vitamin B3 Niacin Bp - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
1-Methyl-6-oxopyridine-3-carboxylic acid
1-Methyl-6-oxopyridine-3-carboxylic acid is an alkaloid with anti-inflammatory activity. Uses: A metabolite of tryptophan-niacin. Synonyms: 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid; 1,6-dihydro-1-methyl-6-oxo-3-pyridinecarboxylic acid. Grades: ≥95%. CAS No. 3719-45-7. Molecular formula: C7H7NO3. Mole weight: 153.14.
2-(Chloromethyl)-6-methoxy-4-methylpyridine
2-(Chloromethyl)-6-methoxy-4-methylpyridine is a trisubstituted Pyridine based building block. Pyridine (P991280) is a heterocyclic ring base present in many biologically active compounds like the vitamins niacin and pyridoxal. Pyridine is used in dehalogenation reactions and can be used as a base in condensation reactions. Group: Biochemicals. Grades: Highly Purified. CAS No. 100636-47-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H10ClNO, Molecular Weight: 171.62. US Biological Life Sciences.
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2-(Chloromethyl)-6-methoxy-4-methylpyridine-D3
2-(Chloromethyl)-6-methoxy-4-methylpyridine-D3 is a deuterium labelled analogue of 2-(Chloromethyl)-6-methoxy-4-methylpyridine (C587835), which is a trisubstituted Pyridine based building block. Pyridine (P991280) is a heterocyclic ring base present in many biologically active compounds like the vitamins niacin and pyridoxal. Pyridine is used in dehalogenation reactions and can be used as a base in condensation reactions. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C8H7D3ClNO, Molecular Weight: 174.64. US Biological Life Sciences.
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3-(2-Chlorophenyl)-2-cyclohexen-1-one
3-(2-Chlorophenyl)-2-cyclohexen-1-one is a useful synthetic intermediate. it is an analog of 3-Phenyl-2-cyclohexen-1-one (P319925) which is used to prepare niacin receptor agonists for the treatment of dyslipidemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 854726-05-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C12H11ClO, Molecular Weight: 206.67. US Biological Life Sciences.
Worldwide
3-Pyridinecarboxaldehyde
3-Pyridinecarboxaldehyde is a substituted pyridine with niacin activity. 3-Pyridinecarboxaldehyde is a component of tobacco smoke. Group: Biochemicals. Alternative Names: Nicotinaldehyde; 3-Formylpyridine; 3-Pyridinaldehyde; 3-Pyridinealdehyde; 3-Pyridylaldehyde; 3-Pyridylcarboxaldehyde; 3-Pyridylcarboxyalde hyde; NSC 8952; Nicotinealdehyde; Nicotinic aldehyde; Pyridine-3-carbaldehyde; Pyridine-5-carboxaldehyde; Rowalind; m-Formylpyridine; β-Formylpyridine; β -Pyridinecarbonalde hyde. Grades: Highly Purified. CAS No. 500-22-1. Pack Sizes: 100g. US Biological Life Sciences.
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4-Oxocyclohexane-1-Carbonitrile
4-Oxocyclohexane-1-Carbonitrile (CAS# 34916-10-4) is used to prepare nicotinamides as PDE4 D isoenzymes inhibitors. It is also used as an anthranilic acid replacement in niacin receptor agonist. Synonyms: 4-oxocyclohexanecarbonitrile; 4-Oxo-cyclohexanecarbonitrile. CAS No. 34916-10-4. Molecular formula: C7H9NO. Mole weight: 123.15.
6-hydroxynicotinate dehydrogenase
Contains [2Fe-2S] iron-sulfur centres, FAD and molybdenum. It also has a catalytically essential, labile selenium that can be removed by reaction with cyanide. In Bacillus niacini, this enzyme is required for growth on nicotinic acid. Group: Enzymes. Synonyms: 6-hydroxynicotinic acid hydroxylase; 6-hydroxynicotinic acid dehydrogenase; 6-hydroxynicotinate hydroxylase; 6-hydroxynicotinate:O2 oxidoreductase. Enzyme Commission Number: EC 1.17.3.3. CAS No. 122191-32-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1089; 6-hydroxynicotinate dehydrogenase; EC 1.17.3.3; 122191-32-6; 6-hydroxynicotinic acid hydroxylase; 6-hydroxynicotinic acid dehydrogenase; 6-hydroxynicotinate hydroxylase; 6-hydroxynicotinate:O2 oxidoreductase. Cat No: EXWM-1089.
Acerola cherry extract
Acerola cherry extract. Applications: Nutraceutical food, funtional beverage. Group: Others. Purity: 17%, 25% Vitamin C, or 4:1, 10:1. Appearance: Light yellow or Light red Powder. Source: Acerola fruit extract often used in North America because of its high vitamin C content. Until the discovery of the camu-camu plant, the richest known natural source of vitamin C was the extract of the acerola fruit. Acerola fruit extract contains further substances like provitamin A, vitamin B1, vitamin B2, niacin, protein, iron, phosphorus and calcium. Through this unique combination acerolafruitextract is assumed to have a substantially greater anti-oxidative effect as well as bio availablity than that of synthetical vitamin C. Especially for people with allergies against citrus fruits, acerola fruit extract represents a true alternative. Acerola cherry extract. Cat No: EXTC-168.
Acifran
Acifran (AY 25712), an antihyperlipidemic agent, is an orally active agonist of GPR109A (HM74A) and GPR109B, the high and low affinity receptors for Niacin [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AY 25712. CAS No. 72420-38-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107579.
Acipimox
Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, although it is unclear whether the recommended dose is as effective as are standard doses of nicotinic acid. Acipimox inhibits the production of triglycerides by the liver and the secretion ofVLDL cholesterol, which leads indirectly to a modest reduction in LDL and increase in HDL cholesterol. Synonyms: Acipimox; K-9321; K9321; K 9321; Olbemox; Olbetam. Grades: >98%. CAS No. 51037-30-0. Molecular formula: C6H6N2O3. Mole weight: 154.12.
Acipimox-[13C2,15N2]
Acipimox-[13C2,15N2] is the labelled analogue of Acipimox, which is a niacin derivative used as a hypolipidemic agent. Synonyms: Acipimox-13C2,15N2; 5-Methyl-2-pyrazinecarboxylic Acid 4-Oxide-13C2,15N2; 5-Methylpyrazinecarboxylic Acid 4-Oxide-13C2,15N2; Olbemox-13C2,15N2; Olbetam-13C2,15N2. Grades: 95% by HPLC; 98% atom 13C, 98% atom 15N. Molecular formula: C4[13C]2H6[15N]2O3. Mole weight: 158.10.
Adenine Free Base
Constituent of nucleic acids and coenzymes. Useful in cell culture media, dropout media for yeast selection. Widespread throughout animal and plant tissues combined with niacinamide, d-ribose, and phosphoric acids; a constituent of nucleic acids and coenzymes, such as codehydrase I and II, adenylic acid, coalaninedehydrase. It is used in microbial determination of niacin; in research on heredity, virus diseases, and cancer. Group: Biochemicals. Alternative Names: 6-Aminopurine. Grades: Molecular Biology Grade. CAS No. 73-24-5. Pack Sizes: 25g, 100g, 500g, 1Kg. Molecular Formula: C5H5N5, Molecular Weight: 135.13. US Biological Life Sciences.
Worldwide
Adenine Hydrochloride-15N5
Adenine Hydrochloride-15N5 is the labelled salt of Adenine (A280480), which is widespread throughout animal and plant tissues combined with niacinamide, d-ribose, and phosphoric acids; a constituent of nucleic acids and coenzymes, such as codehydrase I and II, adenylic acid, coalaninedehydrase. It is used in microbial determination of niacin; in research on heredity, virus diseases, and cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C5H515N5.HCl. US Biological Life Sciences.
Worldwide
(±)-α-Tocopherol nicotinate
(±)-α-Tocopherol nicotinate. Synonyms: Vitamin E nicotinate. CAS No. 51898-34-1. Pack Sizes: 5, 25, 100 g in glass bottle. Product ID: CDC10-0089. Molecular formula: C35H53NO3. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; (±)-α-Tocopherol nicotinate; CDC10-0089; 51898-34-1; C35H53NO3; Vitamin E nicotinate; 257-501-4; MFCD03548047; 51898-34-1. Purity: ≥98%. Color: White to yellow. EC Number: 257-501-4. Physical State: Solid or Liquid. Quality Level: 100. Storage: 2-8°C. Application: (±)-α-Tocopherol nicotinate has been used in metabolic studies to assess its biological functions in rats. Boiling Point: 649.0±55.0 °C(Predicted). Melting Point: approximate 38°C. Density: 0.9611 g/cm3. Product Description: α-Tocopherol nicotinate is a fat soluble vitamin. It is an ester of tocopherol and niacin. Niacin is linked to the hydroxyl group of active vitamin E in this ester. α-Tocopherol is a form of vitamin E, which is available through dietary sources. RRR-α-tocopherol is a natural form of α-Tocopherol.
β-Nicotinamide Mononucleotide
Nicotinamide mononucleotide ("NMN" and "β-NMN") is a nucleotide derived from ribose and nicotinamide. Niacinamide (nicotinamide,) is a derivative of vitamin B3, also known as niacin.) As a biochemical precursor of NAD+, it may be useful in the prevention of pellagra. Group: Coenzymes. Synonyms: β-NMN; β-Nicotinamide ribose monophosphate; NMN; Nicotinamide ribotide; Nicotinamide-1-ium-1-β-D-ribofuranoside 5'-phosphate. CAS No. 1094-61-7. Purity: >98%. Mole weight: 334.2 (as anhydrous free acid); 357.2 (as monosodium anhydrate). Storage: Keep dry and away from light, long term storage at -25°C to -15°C. Form: White to Yellowish lyophilized powder. β-NMN; β-Nicotinamide ribose monophosphate; NMN; Nicotinamide ribotide; Nicotinamide-1-ium-1-β-D-ribofuranoside 5'-phosphate. Cat No: COE-001.
Etofibrate
Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations. Uses: Anticholesteremic agents. Synonyms: ethofibrate; Etofibrato; 3-Pyridinecarboxylic acid, 2-[2-(4-chlorophenoxy)-2-methyl-1-oxopropoxy]ethyl ester; Lipo-Merz; Tricerol. Grades: >98%. CAS No. 31637-97-5. Molecular formula: C18H18ClNO5. Mole weight: 363.79.
Fmoc-5-benzyloxy-DL-tryptophan
Fmoc-5-benzyloxy-DL-tryptophan is a derivative of tryptophan that can be used as a substrate for protein engineering, drug discovery, and as a building block for the synthesis of complex molecules. Tryptophan is an essential amino acid that plays an important role in the body, including protein synthesis, serotonin production, and as a precursor for niacin. Uses: Fmoc-5-benzyloxy-dl-tryptophan has various applications in scientific experiments, including protein engineering, drug discovery, and synthesizing complex molecules. fmoc-5-benzyloxy-dl-tryptophan can also be used as a building block for the synthesis of peptides, which can be used in drug development. Additional or Alternative Names: 5-(Benzyloxy)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]tryptoph. Product Category: Amino Acids. CAS No. 1219348-47-6. Molecular formula: C33H28N2O5. Mole weight: 532.6. Purity: Peak Area by HPLC ≥95%. IUPACName: 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(5-phenylmethoxy-1H-indol-3-yl)propanoic acid. Canonical SMILES: C1=CC=C(C=C1)COC2=CC3=C(C=C2)NC=C3CC(C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46. Product ID: ACM1219348476. Alfa Chemistry ISO 9001:2015 Certified.
A cell-permeable Niacin triazolo derivative that acts as a potent and selective agonist toward the human orphan G-protein-coupled receptor GPR109b/HM74, but not GPR109a/HM74A or b-adrenergic receptor. Effectively inhibits cAMP elevation induced by forskolin (5uM) and isoproterenol (1uM), respectively, in GPR109b-expressing CHO cells (EC50=400nM) and freshly isolated human adipocytes (EC50 about 1uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 306935-41-1. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
IBC 293
IBC 293, a cell-permeable niacin triazolo derivative, is a potent and highly selective agonist for human orphan G-protein-coupled receptor GPR109b/HM74 expressed in adipocytes with EC50 value of 400 nM. It is selective for GPR109B over niacin receptor GPR109A and β-adrenergic receptor. It inhibits cAMP elevation induced by isoproterenol and forskolin in freshly isolated human adipocytes and GPR109b-expressing CHO cells. It also inhibits forskolin-stimulated cAMP release in Chinese hamster ovary cells. It also inhibits isoproterenol-stimulated lipolysis in vitro in isolated human adipocytes. It may be relevant to atherosclerosis and dyslipidemia. Synonyms: IBC 293; IBC293; IBC-293. 1-Isopropyl-1,2,3-benzotriazole-5-carboxylic acid; 1-(1-Methylethyl)-1H-benzotriazole-5-carboxylic acid. Grades: ≥99% by HPLC. CAS No. 306935-41-1. Molecular formula: C10H11N3O2. Mole weight: 205.22.
Inositol nicotinate (Hexanicit) has vasodilating effects and can be used in research on peripheral arterial disease, showing efficacy when taken orally. Inositol nicotinate does not significantly improve triglyceride levels in mice induced by biphenyl esters [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Inositol niacinate; Hexanicit. CAS No. 6556-11-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-122365.
Inositol nicotinate
Inositol nicotinate, with vasodilatory effect, is used in the study of Peripheral arterial disease (PAD)[1]. Synonyms: Inositol niacinate; myo-Inositol hexanicotinate. CAS No. 6556-11-2. Molecular formula: C42H30N6O12. Mole weight: 810.72.
Laropiprant
a drug used in combination with niacin to reduce blood cholesterol (LDL and VLDL) that is no longer sold. Uses: A potent, selective dp1 receptor antagonist. Synonyms: (3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydro-5-(methylsulfonyl)-cyclopent[b]indole-3-acetic acid. Grades: > 95%. CAS No. 571170-77-9. Molecular formula: C21H19ClFNO4S. Mole weight: 435.91.
L-Tryptophan
L-tryptophan is one of the essential amino acids of the human body, is the precursor of the human body's important neurotransmitter - 5-hydroxytryptophan, used in nutritional supplements for pregnant women and special milk powder for milk children, used in the treatment of niacin deficiency (pellagra), often as a nutritional supplement, antioxidant. CAS No. 73-22-3. Product ID: CDF4-0220. Molecular formula: C11H12N2O2. Category: Amino acid. Product Keywords: Amino Acids; L-Tryptophan; CDF4-0220; Amino acid; C11H12N2O2; 73-22-3. Grade: Food Grade. Color: White to yellow-white. EC Number: 200-795-6. Physical State: powder. Solubility: 20% NH3: 0.1 g/mL at 20 °C, clear, colorless. Storage: 2-8°C. Boiling Point: 342.72°C (rough estimate). Melting Point: 289-290 °C (dec.)(lit.). Density: 1.34.
MK-0354
MK-0354 is a partial agonist of Niacin receptor, G-protein coupled receptor 109a. Its EC50 value is 1.65/1.08 μM for hGPR109a/ mGPR109a, which show no activation of GPR109b in the cAMP assay at any concentration up to 100 μM. It demonstrated clear and statistically significant partial agonism in the cAMP assays for both the mouse and human receptors with efficacy approximately 60-70% of that of either nicotinic acid or β-hydroxy butyrate in vitro. It appeared to be somewhat unique among the members of the pyrazole tetrazole series in having reasonable receptor activity. It retained the plasma free fatty acid lowering effects in mice, but did not induce vasodilation at the maximum feasible dose in vivo. It could activate the antilipolytic pathway in adipocytes. It was developed by Arena pharmaceuticals and Merck Serono together. It had been in the two phase of clinical and been used for the treatment of atherosclerosis, but it was terminated in 2006. Uses: Mk-0354 could activate the antilipolytic pathway in adipocytes. had been used for the treatment of atherosclerosis. Synonyms: MK-0354; MK0354; MK 0354; 3-(1H-tetrazol-5-yl)-1, 4, 5, 6-tetrahydrocyclopenta[c]pyrazole;1, 4, 5, 6-Tetrahydro-3-(1H-tetrazol-5-yl)cyclopenta[c]pyrazole. Grades: >98%. CAS No. 851776-28-8. Molecular formula: C7H8N6. Mole weight: 176.18.
Nicodicosapent is a fatty acid niacin conjugate that is also an inhibitor of the sterol regulatory element binding protein (SREBP) , a key regulator of cholesterol metabolism proteins such as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1. Uses: Scientific research. Group: Signaling pathways. CAS No. 1269181-69-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17640.
Nicotinamide
Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity ( IC 50 : 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD + , ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti- HBV activity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Niacinamide; Nicotinic acid amide. CAS No. 98-92-0. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-B0150.
Nicotinamide
Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Aminicotin. Product Category: Inhibitors. Appearance: White powder. CAS No. 98-92-0. Molecular formula: C6H6N2O. Mole weight: 122.12. Purity: 99%+. IUPACName: Pyridine-3-carboxamide. Canonical SMILES: C1=CC(=CN=C1)C(=O)N. Density: 1.40 g/cm³. ECNumber: 202-713-4. Product ID: ACM98920-1. Alfa Chemistry ISO 9001:2015 Certified.
Nicotinamide
Nicotinamide is a NAD+ and NADP+ coenzyme precursor. Nicotinamide is an antiinflammatory agent and a PARP-1 enzyme inhibitor. Applications: An nad+ and nadp+ coenzyme precursor. Group: Coenzymes. Synonyms: Niacinamide; Nicotinic Acid Amide; Pyridine-3-carboxylic acid amide. CAS No. 98-92-0. Purity: ≥98%. Mole weight: 122.1. Form: Solid. Niacinamide; Nicotinic Acid Amide; Pyridine-3-carboxylic acid amide; Nicotinamide; 98-92-0. Cat No: COEC-008.
Nicotinamide-2,4,5,6-d4
Nicotinamide-2,4,5,6-d4. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Niacinamide; 3-Pyridinecarboxamide; Vitamin B 3. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 347841-88-7. Molecular formula: C6H2D4N2O. Mole weight: 126.15. Purity: 98 atom % D. Product ID: ACM347841887. Alfa Chemistry ISO 9001:2015 Certified.
Nicotinamide hydrochloride
Nicotinamide Hydrochloride is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide Hydrochloride also inhibits SIRT1. Nicotinamide Hydrochloride increases cellular NAD+, ATP, ROS levels. Nicotinamide Hydrochloride inhibits tumor growth and improves survival. Nicotinamide Hydrochloride also has anti-HBV activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NIACINAMIDE HYDROCHLORIDE;NICOTINAMIDE HYDROCHLORIDE;nicotinamideHCl;Einecs 246-862-3. Product Category: Inhibitors. CAS No. 25334-23-0. Molecular formula: C6H7ClN2O. Mole weight: 158.59. Product ID: ACM25334230. Alfa Chemistry ISO 9001:2015 Certified.
Nicotinamide-N-oxide
Nicotinamide N-oxide, a metabolite of Nicotinamide, is a potent, and selective antagonist of the CXCR2 receptor and used in studies of mechanisms of niacin-related granulocyte differentiation of cells. Synonyms: 1-oxidopyridin-1-ium-3-carboxamide; nicotinamide N-oxide. Grades: > 95%. CAS No. 1986-81-8. Molecular formula: C6H6N2O2. Mole weight: 138.12.
Nicotinamide riboside chloride
Nicotinamide riboside Chloride, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities [1]. Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimers disease [2]. Uses: Scientific research. Group: Natural products. CAS No. 23111-00-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-123033A.
The enzyme, which is involved in pyridine nucleotide recycling, can form β-nicotinate D-ribonucleotide and diphosphate from nicotinate and 5-phospho-α-D-ribose 1-diphosphate (PRPP) in the absence of ATP. However, when ATP is available the enzyme is phosphorylated resulting in a much lower Km for nicotinate. The phospho-enzyme is hydrolysed during the transferase reaction, regenerating the low affinity form. The presence of ATP shifts the products/substrates equilibrium from 0.67 to 1100. Group: Enzymes. Synonyms: niacin ribonucleotidase; nicotinic acid mononucleotide glycohydrolase; nicotinic acid mononucleotide pyrophosphorylase; nicotinic acid phosphoribosyltransferase; nicotinate-nucleotide:diphosphate phospho-α-D-ribosyltransferase. Enzyme Commission Number: EC 6.3.4.21. CAS No. 9030-26-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5791; nicotinate phosphoribosyltransferase; EC 6.3.4.21; 9030-26-6; niacin ribonucleotidase; nicotinic acid mononucleotide glycohydrolase; nicotinic acid mononucleotide pyrophosphorylase; nicotinic acid phosphoribosyltransferase; nicotinate-nucleotide:diphosphate phospho-α-D-ribosyltransferase. Cat No: EXWM-5791.
Nicotinic Acid is a major chemical component of coenzymes NAD+ and NADP+ (a major electron acceptor molecule in biological oxidations). Applications: A major chemical component of coenzymes nad+ and nadp+. Group: Coenzymes. Synonyms: Niacin. CAS No. 59-67-6. Purity: 0.99. Mole weight: 123.1. Form: Solid. Niacin; Nicotinic Acid; 59-67-6. Cat No: COEC-010.
Nicotinic Acid-13C6,d4
Labeled Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver, fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term niacin has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor). Group: Biochemicals. Alternative Names: 3-Pyridinecarboxylic Acid-13C6,d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Nicotinic Acid, 99.5-100.5% USP
Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver , fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term niacin has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor). Group: Biochemicals. Alternative Names: Nicotinic acid; Vitamin B3; 3-Pyridinecarboxylic Acid; 3-Carboxylpyridine; 3-Carboxypyridine; Akotin; Apelagrin; Niacin; Niacor; Niaspan; Nicacid; Pelonin; Vitamin B5; Wampocap; β-Pyridinecarboxylic Acid. Grades: USP. CAS No. 59-67-6. Pack Sizes: 100g, 500g, 1Kg. US Biological Life Sciences.
Worldwide
Nicotinic Acid-d1
Labeled Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver, fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term niacin has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor). Group: Biochemicals. Alternative Names: 3-Pyridinecarboxylic Acid-d1; 3-Carboxylpyridine-d1; 3-Carboxypyridine-d1; Akotin-d1; Apelagrin-d1; Niacin-d1; Niacor-d1; Niaspan-d1; Nicacid-d1; Pelonin-d1; Vitamin B3-d1; Vitamin B5-d1; Wampocap-d1; β-Pyridinecarboxylic Acid-d1. Grades: Highly Purified. CAS No. 116975-14-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Nicotinic Acid-d3 (major)
Labeled Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver, fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term niacin has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor). A representative lot contains >20% d4. Group: Biochemicals. Alternative Names: 3-Pyridinecarboxylic Acid-d3; 3-Carboxylpyridine-d3; 3-Carboxypyridine-d3; Akotin-d3; Apelagrin-d3; Niacin-d3; Niacor-d3; Niaspan-d3; Nicacid-d3; Pelonin-d3; Vitamin B3-d3; Vitamin B5-d3; Wampocap-d3; β-Pyridinecarboxylic Acid-d3. Grades: Highly Purified. CAS No. 861405-75-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Nicotinic Acid-d4
Labeled Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver, fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term niacin has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor). Group: Biochemicals. Alternative Names: 3-Pyridinecarboxylic Acid-d4. Grades: Highly Purified. CAS No. 66148-15-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Nicotinuric Acid-d4
A labeled Niacin analog for therapeutic use. Group: Biochemicals. Alternative Names: N-[(3-Pyridinyl-d4)carbonyl]glycine; N-(Nicotinoyl)-d4-glycine; 2-(Nicotinylamino-d4)acetic Acid; NSC 71273-d4; (Nicotinoyl-d4)glycine; (Nicotinyl-d4)glycine. Grades: Highly Purified. CAS No. 1216737-36-8. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C?H?D?N?O?, Molecular Weight: 184.19. US Biological Life Sciences.
Worldwide
Nudifloric Acid
A metabolite of Tryptophan-niacin. Group: Biochemicals. Alternative Names: 1,6-Dihydro-1-methyl-6-oxo-3-pyridinecarboxylic Acid; Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic Acid; 1-Methyl-6-pyridone-3-carboxylic Acid; 1-Methylpyridin-2-one-5-carboxylic Acid. Grades: Highly Purified. CAS No. 3719-45-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Pyridine Hydrochloride
Pyridine Hydrochloride is the hydrochloride salt of pyridine, a basic six-membered heterocyclic ring. Pyridine is a base structure present in many biologically active compounds like the vitamins niacin and pyridoxal. Pyridine is used in dehalogenation reactions and can be used as a base in condensation reactions. Group: Biochemicals. Alternative Names: Pyridinium Chloride. Grades: Highly Purified. CAS No. 628-13-7. Pack Sizes: 100g. US Biological Life Sciences.
Worldwide
Trigonelline Hydrochloride
Trigonelline is a pyridine alkaloid found in various edible seeds and legumes, including coffee. It is a zwitterion formed by the methylation of the nitrogen atom of niacin (vitamin B3; nicotinic acid) and, as a product of niacin metabolism, is excreted in urine of mammals.1 Trigonelline has been used to reduce blood glucose levels and to inhibit PPARγ expression in rat models of diabetes.2,3 It is also reported to inhibit the migration of hepatocarcinoma cells and render them more susceptible to apoptosis by reducing Raf/ERK/Nrf2 protein levels and activities of anti-oxidative enzymes further downstream, such as SOD, catalase, and glutathione peroxidase.4,5. Group: Biochemicals. Alternative Names: 1-Methylpyridinium-3-carboxylate hydrochloride; N-Methylnicotinic acid betaine hydrochloride. Grades: Plant Grade. CAS No. 6138-41-6. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C7H8ClNO2, Molecular Weight: 173.6. US Biological Life Sciences.
Worldwide
Xanthinol Nicotinate
Xanthinol Nicotinate (Xanthinol Niacinate), a vasodilator, can act directly on the smooth muscle of small arteries and capillaries. Xanthinol Nicotinate expands blood vessels, improves blood rheology and reduces peripheral vascular resistance [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Xanthinol Niacinate. CAS No. 437-74-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B1815.