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| Product | Description | |
|---|---|---|
| Novobiocin | Novobiocin (Albamycin) is a potent and orally active antibiotic. Novobiocin also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin shows anti-orthopoxvirus activity [1] [2] [3] [4] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Albamycin; Cathomycin. CAS No. 303-81-1. Pack Sizes: 5 mg. Product ID: HY-B0425. |  |
| Novobiocin | Novobiocin (Albamycin) is a potent and orally active antibiotic. Novobiocin also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin shows anti-orthopoxvirus activity. Group: Inhibitors. CAS No. 303-81-1. Molecular formula: C31H36N2O11. Mole weight: 612.628. Catalog: ACM303811. |  |
| Novobiocin | Novobiocin is an aminocoumarin antibiotic isolated from a number of species of Streptomyces. Novobiocin exhibits broad spectrum Gram +ve activity and was used clinically. Novobiocin is a potent inhibitor of bacterial DNA gyrase and acts as a competitive inhibitor of the ATPase reaction catalysed by GyrB. Group: Biochemicals. Grades: Highly Purified. CAS No. 303-81-1. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Novobiocin | Novobiocin is found to bind at a second ATP-binding site in the C-terminal domain of Hsp90, thus disrupting the interaction of both p23 and Hsp70 co-chaperones with the Hsp90 complex. (IC50=700μmol/L). Synonyms: Streptonivicin; Inamycin; Albamycin; Cathomycin; Cardelmycin; Spheromycin; Antibiotic PA-93; Novobiocina; Benzamide, N-(7-((3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-beta-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl)-4-hydroxy-3-(3-methyl-2-butenyl)-. Grades: >95%. CAS No. 303-81-1. Molecular formula: C31H36N2O11. Mole weight: 612.62. |  |
| Novobiocin sodium | Novobiocin (Albamycin) sodium is a potent and orally active antibiotic. Novobiocin sodium also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin sodium has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin sodium shows anti-orthopoxvirus activity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Albamycin sodium; Cathomycin sodium. CAS No. 1476-53-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0425A. | |
| Novobiocin sodium salt | 1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C31H35N2NaO11. CAS No. 1476-53-5. Prepack ID 51758785-1g. Molecular Weight 634.61 g/mol. See USA prepack pricing. |  |
| Novobiocin sodium salt | 5g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C31H35N2NaO11. CAS No. 1476-53-5. Prepack ID 51758785-5g. Molecular Weight 634.61 g/mol. See USA prepack pricing. | |
| Novobiocin Sodium Salt | Novobiocin is an antibiotic that acts as an inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Studies show that Novobiocin is also an inhibitor of retrovirus RNA-dependent DNA-polymerase. Novobiocin is used in the production of positively supercoiled plasmid DNA. Group: Biochemicals. Alternative Names: N-[7-[[3-O-(Aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-α-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-(3-methyl-2-butenyl)benzamide monosodium salt; Albamycin Sodium; Cathomycin Sodium; Cathomycin Sodium Lyovac; NSC 2382; Vulcamycin. Grades: Highly Purified. CAS No. 1476-53-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 11-Hydroxynovobiocin | 11-Hydroxynovobiocin is a novobiocin homolog produced by Sebekia benihana UC 5762 (NRRL 11111). It has anti-gram-negative bacteria effect, and its activity is equivalent to 30% of novobiocin. Molecular formula: C31H36N2O12. Mole weight: 628.62. | |
| decarbamoylnovobiocin carbamoyltransferase | The enzyme catalyses the last step in the biosynthesis of the aminocoumarin antibiotic novobiocin. The reaction is activated by ATP. Group: Enzymes. Synonyms: novN (gene name). Enzyme Commission Number: EC 2.1.3.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2014; decarbamoylnovobiocin carbamoyltransferase; EC 2.1.3.12; novN (gene name). Cat No: EXWM-2014. |  |
| demethyldecarbamoylnovobiocin O-methyltransferase | The enzyme is involved in the biosynthesis of the aminocoumarin antibiotic novobiocin. Group: Enzymes. Synonyms: NovP. Enzyme Commission Number: EC 2.1.1.285. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1892; demethyldecarbamoylnovobiocin O-methyltransferase; EC 2.1.1.285; NovP. Cat No: EXWM-1892. | |
| Descarbamylnovobiocin | Descarbamylnovobiocin is a derivative of novobiocin and it is a hydroxycoumarin that is novobiocin lacking the carbamoyl group from position 3 on the hexose ring. Synonyms: Novclobiocin 103. Grades: >95% by HPLC. CAS No. 75057-97-5. Molecular formula: C30H35NO10. Mole weight: 569.60. | |
| Dihydronovobiocin | Dihydronovobiocin is a derivative of novobiocin. It is active against the bacteria S. aureus, S. haemolyticus, D. pneumoniae, S. typhosa, K. pneumoniae, and P. multocida (MICs = 0.6, 2, 0.6, 10, 10, and 3 μg/ml, respectively). Dihydronovobiocin inhibits DNA gyrase subunit B with an IC50 value of 64.5 nM. Synonyms: N-[7-[[3O-(aminocarbonyl)-6-deoxy-5C-methyl-4O-methyl-α-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1benzopyran-3-yl]-4-hydroxy-3-(3-methylbutyl)-benzamide. Grades: >95% by HPLC. CAS No. 29826-16-2. Molecular formula: C31H38N2O11. Mole weight: 614.64. | |
| 4-hydroxyphenylpyruvate 3-dimethylallyltransferase | The enzyme is involved in the biosynthesis of the 3-dimethylallyl-4-hydroxyphenylpyruvate moiety of the aminocoumarin antibiotics clorobiocin and novobiocin. Group: Enzymes. Synonyms: CloQ; 4HPP dimethylallyltransferase; NovQ. Enzyme Commission Number: EC 2.5.1.111. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2727; 4-hydroxyphenylpyruvate 3-dimethylallyltransferase; EC 2.5.1.111; CloQ; 4HPP dimethylallyltransferase; NovQ. Cat No: EXWM-2727. | |
| 8-demethylnovobiocic acid C8-methyltransferase | The enzyme is involved in the biosynthesis of the aminocoumarin antibiotic novobiocin. Group: Enzymes. Synonyms: NovO. Enzyme Commission Number: EC 2.1.1.284. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1891; 8-demethylnovobiocic acid C8-methyltransferase; EC 2.1.1.284; NovO. Cat No: EXWM-1891. | |
| 8-demethylnovobiocic acid synthase | The enzyme is involved in the biosynthesis of the aminocoumarin antibiotic novobiocin. Group: Enzymes. Synonyms: novL (gene name); novobiocin ligase; novobiocic acid synthetase (misleading); 8-desmethyl-novobiocic acid synthetase; 8-demethylnovobiocic acid synthetase. Enzyme Commission Number: EC 6.3.1.15. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5718; 8-demethylnovobiocic acid synthase; EC 6.3.1.15; novL (gene name); novobiocin ligase; novobiocic acid synthetase (misleading); 8-desmethyl-novobiocic acid synthetase; 8-demethylnovobiocic acid synthetase. Cat No: EXWM-5718. | |
| Acetamidomalonic acid diethyl ester | Acetamidomalonic acid diethyl ester (CAS# 1068-90-2) is a versatile building block used for the synthesis of various pharmaceutical and biologically active compounds. It is an intermediate for the preparation of Novobiocin (N888500) analogues as potential heat shock protein 90 inhibitors. Synonyms: Diethyl acetamidomalonate. Grades: ≥ 99 % (Assay). CAS No. 1068-90-2. Molecular formula: C9H15NO5. Mole weight: 217.20. | |
| Chlorobiocin | Chlorobiocin is produced by the strain of Streptomyces hygroscopicus DS 9751 and Novobiocin. Chlorobiocin is found to bind at a second ATP-binding site in the C-terminal domain of Hsp90, thus disrupting the dimerization of the Hsp90 complex. IC50=60 μmol/L. Synonyms: Clorobiocin; Antibiotic RP 18,631; NSC 227186. Grades: >98%. CAS No. 39868-96-7. Molecular formula: C35H37ClN2O11. Mole weight: 697.13. | |
| Coumermycin A1 | Coumemycin A1 is found to bind at a second ATP-binding site in the C-terminal domain of Hsp90, IC50 70 μmol/L. It is produced by the strain of Streptomyces rishirensis, Str. spinichromogene and Str. Spinicoumarensis. It has anti-gram positive bacteria, negative bacteria, mycobacterium (weak) activity, cross-resistance with Novobiocin. Uses: Topoisomerase ii inhibitors. Synonyms: coumermycin a1; Coumamycine; Coumamycinum; Cumamicina; Notomycin; Coumamycin; Notomycin A1; Sugordomycin D-1a; Sugordomycin; Antibiotic Bu-620. Grades: >98%. CAS No. 4434-5-3. Molecular formula: C55H59N5O20. Mole weight: 1110.09. | |
| Irgasan (5-Chloro-2- (2, 4-dichlorophenoxy) phenol, Triclosan, Trichlorosan) | Irgasan, diphenyl ether derivative, is used as a component of cefsulodin-irgasan-novobiocin selection medium for Yersinia, a human pathogen that may contaminate animal-source food products. Because of its low antigenicity, irgasan is also a component of many antibacterial consumer products. Group: Biochemicals. Alternative Names: 5-Chloro-2-(2,4-dichloro-3,5,6-d3-phenoxy)phenol; 2,4,4'-Trichloro-2'-hydroxydiphenyl ether; Triclosan; Trichlorosan. Grades: Highly Purified. CAS No. 3380-34-5. Pack Sizes: 5g, 25g. Molecular Formula: C12H7Cl3O2, Molecular Weight: 289.54. US Biological Life Sciences. | Worldwide |
| L-demethylnoviosyl transferase | The enzyme is involved in the biosynthesis of the aminocoumarin antibiotic, novobiocin. Group: Enzymes. Synonyms: novM (gene name); dTDP-β-L-noviose:novobiocic acid 7-O-noviosyltransferase; L-noviosyl transferase. Enzyme Commission Number: EC 2.4.1.302. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2537; L-demethylnoviosyl transferase; EC 2.4.1.302; novM (gene name); dTDP-β-L-noviose:novobiocic acid 7-O-noviosyltransferase; L-noviosyl transferase. Cat No: EXWM-2537. | |
| TPU-0031-A | TPU-0031-A is an antibiotic of the novobiocin group produced by Streptomyces sp. TP-A0556. It shows antibiotic activity against Gram-positive and -negative bacteria. Molecular formula: C30H34N2O11. Mole weight: 598.6. | |
| TPU-0031-B | TPU-0031-B is an antibiotic of the novobiocin group produced by Streptomyces sp. TP-A0556. It shows antibiotic activity against Gram-positive and -negative bacteria. Molecular formula: C30H34N2O11. Mole weight: 598.6. | |
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