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1-Hexyl-3-methylimidazolium tetrafluoroborate Enzyme catalysis in ionic liquids. Uses: Metal plating, electropolishing, metal reprocessing, phase transfer media, batteries fuel cells, nanomaterials, industrial solvents, nuclear fuel red waste, enzymatic catalysis, lubricants heat transfer and solar energy conversion. Group: Electrolytesbattery materials. Alternative Names: HMIMBF4. CAS No. 244193-50-8. Product ID: 1-hexyl-3-methylimidazol-3-ium; tetrafluoroborate. Molecular formula: 254.08. Mole weight: C10H19BF4N2. [B-](F)(F)(F)F.CCCCCCN1C=C[N+](=C1)C. 1S/C10H19N2. BF4/c1-3-4-5-6-7-12-9-8-11(2)10-12; 2-1(3, 4)5/h8-10H, 3-7H2, 1-2H3; /q+1; -1. MFXLOVLEQJRXFP-UHFFFAOYSA-N. >97.0%(N). Alfa Chemistry Materials 7
1-Hexyl-3-methylimidazolium tetrafluoroborate Enzyme catalysis in ionic liquids. Uses: Metal plating, electropolishing, metal reprocessing, phase transfer media, batteries fuel cells, nanomaterials, industrial solvents, nuclear fuel red waste, enzymatic catalysis, lubricants heat transfer and solar energy conversion. Group: Imidazolium ionic liquids. Alternative Names: HMIMBF4. CAS No. 244193-50-8. Molecular formula: C10H19BF4N2. Mole weight: 254.08. Appearance: Light yellow to Brown clear liquid. Purity: >97.0%(N). IUPACName: 1-hexyl-3-methylimidazol-3-ium;tetrafluoroborate. Canonical SMILES: [B-](F)(F)(F)F.CCCCCCN1C=C[N+](=C1)C. Density: 1.15 g/cm³ (24 °C). Catalog: ACM244193508. Alfa Chemistry.
(24S)-24,25-Epoxycholesterol (24S)-24,25-Epoxycholesterol is a derivative of 4 β-Hydroxy Cholesterol (H917980), a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Group: Biochemicals. Grades: Highly Purified. CAS No. 77058-74-3. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C27H44O2, Molecular Weight: 400.64. US Biological Life Sciences. USBiological 10
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25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt 25-Hydroxy-cholesterol 3-Sulfate Ester is a derivative of 4 β-Hydroxy Cholesterol (H917980), a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Group: Biochemicals. Grades: Highly Purified. CAS No. 1174047-40-5. Pack Sizes: 1mg. Molecular Formula: C27H45NaO5S, Molecular Weight: 504.7. US Biological Life Sciences. USBiological 10
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25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt-d6 25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt-d6 is the isotope labelled analog of 25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt (H825760). 25-Hydroxy-cholesterol 3-Sulfate Ester is a derivative of 4 β-Hydroxy Cholesterol (H917980), a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C27H39D6NaO5S, Molecular Weight: 510.73. US Biological Life Sciences. USBiological 10
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4-beta-Hydroxy Cholesterol 4-beta-Hydroxy Cholesterol is a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. It is also a potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Synonyms: (3β,4β)-Cholest-5-ene-3,4-diol; Cholest-5-ene-3β,4β-diol; 3β,4β-Dihydroxycholest-5-ene; cis-3,4-Dihydroxy-5-cholestene; cis-5-Cholestene-3,4-diol. Grades: > 95%. CAS No. 17320-10-4. Molecular formula: C27H46O2. Mole weight: 402.65. BOC Sciences 7
BGC 20-1531 hydrochloride BGC 20-1531 hydrochloride is a potent and selective EP4 antagonist, which exhibits <50% inhibition at 47 ion channels, cell-surface transporters, enzymes, and nuclear receptors. It has high affinity and selective with Ki of 3 nM for EP4 antagonist. BGC 20-1531 antagonizes PGE2-induced cAMP accumulation in a dose-dependent manner in HEK293 EBNA. It also reverses PGE2-induced vasorelaxation with Kb of 15.85 nM in human middle cerebral and middle meningeal arterial rings. Synonyms: BGC20-1531 HCl; BGC20-1531 hydrochloride; BGC20-1531; BGC 20-1531; BGC-20-1531; BGC201531; BGC 201531; BGC-201531; PGN 1531; PGN-1531; PGN1531. Grades: ≥98%. CAS No. 1962928-26-2. Molecular formula: C26H24N2O6S·HCl. Mole weight: 529. BOC Sciences 10
BMN-673 8R,9S BMN-673 is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity. PARP inhibitor BMN-673 selectively binds to PARP and prevents PARP-mediated DNA repair of single strand DNA breaks via the base-excision repair pathway. This enhances the accumulation of DNA strand breaks, promotes genomic instability and eventually leads to apoptosis. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins that signal and recruit other proteins to repair damaged DNA and is activated by single-strand DNA breaks. BMN-673 has been proven to be highly active in mouse models of human cancer and also appears to be more selectively cytotoxic with a longer half-life and better bioavailability as compared to other compounds in development. Synonyms: Talazoparib (8R,9S); (8R,9S)-BMN-673; BMN673 (8R,9S); BMN 673 (8R,9S). Grades: >98%. CAS No. 1207456-00-5. Molecular formula: C19H14F2N6O. Mole weight: 380.35. BOC Sciences 10
Bromoenol lactone BEL is a selective, potent, irreversible, mechanism-based inhibitor of myocardial cytosolic calcium-independent phospholipase A2 (iPLA2) with a Ki value of 180 nM. BEL induces the proteolysis of procaspase-9 and procaspase-3 and increases cleavage of poly (ADP-ribose) polymerase. BEL also inhibits macrophage iPLA2 in a concentration-dependent manner with an IC50 value of 60 nM and is an effective enzyme-activated irreversible inhibitor of chymotrypsin Ki of 636 nM. Long term treatment with BEL increased annexin-V binding to the cell surface and nuclear DNA damage. Synonyms: BEL; Haloenol lactone; HELSS. Grades: ≥95%. CAS No. 88070-98-8. Molecular formula: C16H13BrO2. Mole weight: 317.2. BOC Sciences 10
Caspase 3 Human, Recombinant Caspase 3 is a member of the CED-3 subfamily of caspases and is responsible for the cleavage of many key proteins such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP), the inhibitor of caspase-activated deoxyribonuclease (ICAD), and gelsolin, a protein involved in apoptosis regulation. Caspase 3 is considered to be an effector caspase, activating pro-caspase 6 and pro-caspase 9 in vitro. Caspase 3 can be activated by caspase 8, caspase 6, and granzyme B. Human recombinant c-terminal histidine tagged caspase 3 is a fully active protein consisting of 17 kda and 13.5 kda subunits; the 13.5 kda subunit contains the histidine tag. Applications: Caspase-3 is a caspase prote...ve enzyme. this protein cleaves and activates caspases 6 and 7; and the protein itself is processed and activated by caspases 8, 9, and 10. it is the predominant caspase involved in the cleavage of amyloid-beta 4a precursor protein, which is associated with neuronal death in alzheimer's disease. alternative splicing of this gene results in two transcript variants that encode the same protein. caspase-3 shares many of the typical characteristics common to all currently-known caspases. for example, its active site contains a cysteine residue (cys-163) and histidine residue (his-121) that stabilize the peptide bond cleavage of a protein sequence to the carboxy-terminal side of an Creative Enzymes
caspase-6 Caspase-6 is an effector/executioner caspase, as are caspase-3 (EC 3.4.22.56) and caspase-7 (EC 3.4.22.60). These caspases are responsible for the proteolysis of the majority of cellular polypeptides [e.g. poly(ADP-ribose) polymerase (PARP)], which leads to the apoptotic phenotype. Caspase-6 can cleave its prodomain to produce mature caspase-6, which directly activates caspase-8 (EC 3.4.22.61) and leads to the release of cytochrome c from the mitochondria. The release of cytochrome c is an essential component of the intrinsic apoptosis pathway. The enzyme can also cleave and inactivate lamins, the intermediate filament scaffold proteins of the nuclear envelope, leading to nuclear fragmentation in the final phases of apoptosis. Belongs in peptidase family C14. Group: Enzymes. Synonyms: CASP-6; apoptotic protease Mch-2; Mch2. Enzyme Commission Number: EC 3.4.22.59. CAS No. 182372-15-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4234; caspase-6; EC 3.4.22.59; 182372-15-2; CASP-6; apoptotic protease Mch-2; Mch2. Cat No: EXWM-4234. Creative Enzymes
CEP-9722 CEP-9722 is a small-molecule prodrug of CEP-8983, a novel 4-methoxy-carbazole inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration and conversion from CEP-9722, CEP-8983 selectively binds to PARP 1 and 2, preventing repair of damaged DNA via base excision repair (BER). This agent enhances the accumulation of DNA strand breaks and promotes genomic instability and apoptosis. CEP-8983 may potentiate the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins that signal and recruit other proteins to repair damaged DNA and can be activated by single strand breaks in DNA. Synonyms: CEP 9722; CEP9722; 11-methoxy-2-((4-methylpiperazin-1-yl)methyl)-4,5,6,7-tetrahydro-1H-cyclopenta[a]pyrrolo[3,4-c]carbazole-1,3(2H)-dione. CAS No. 916574-83-9. Molecular formula: C24H26N4O3. Mole weight: 418.49. BOC Sciences 11
CH-223191 CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist with IC50 of 30 nM.CH223191 can prevent 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a widespread environmental pollutant with many toxic effects, including endocrine disruption, reproductive dysfunction, immunotoxicity, liver damage, and cancer. CH223191 potently inhibits TCDD-induced AhR-dependent transcription. In addition, CH-223191 blocked the binding of TCDD to AhR and inhibited TCDD-mediated nuclear translocation and DNA binding of AhR. These inhibitory effects of CH-223191 prevented the expression of cytochrome P450 enzymes, target genes of the AhR. CH-223191, may be a useful agent for the study of AhR-mediated signal transduction and the prevention of TCDD-associated pathology. Synonyms: CH223191; CH-223191; CH 223191. Grades: >98%. CAS No. 301326-22-7. Molecular formula: C19H19N5O. Mole weight: 333.39. BOC Sciences 11
DACA DACA inhibits two essential nuclear enzymes in vitro, DNA topoisomerase I and DNA topoisomerase (topo) II. DACA stabilises topo I, topo II alpha, and topo II beta cleavable complexes in human leukaemia CCRF-CEM cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 89459-25-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100777. MedChemExpress MCE
Danshensu Danshensu is an active component of Salvia miltiorrhiza that shows wide cardiovascular benefit. It suppresses the formation of reactive oxygen species and inhibits platelet adhesion and aggregation. It also protects myocardium from the reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation. It increases production of collagenin Detroit 551 cells and attenuates the α-MSH-stimulated melanin production of B16 cells. It may be used as active ingredients in would healing, cosmetic treatments or treating hyperpigmentation. It significantly decreased the level of the marker enzymes (creatine kinase and lactate dehydrogenase) from the coronary effluents and myocardial infarction size in vitro. It also had ROS scavenging activity and boosted endogenous antioxidants such as SOD, CAT, MDA, GSH-PX and HO-1 activities by activating nuclear factor erythroid-2-related factor 2 (Nrf2) signaling pathway which was mediated by Akt and ERK1/2 in western blot analysis. It significantly lowered tHcy in rats with elevated tHcy. Danshensu is a natural compound, which can also be used in cosmetics material. Synonyms: Benzenepropanoic acid, α,3,4-trihydroxy-, (αR)-; (αR)-α,3,4-Trihydroxybenzenepropanoic acid; Benzenepropanoic acid, α,3,4-trihydroxy-, (R)-; (R)-(+)-3-(3,4-Dihydroxyphenyl)lactic acid; (R)-3-(3,4-Dihydroxyphenyl)-2-hydroxypropionic acid; 3-(3',4'-Dihydroxyphenyl)-(2R)-lactic acid; D-(+)-β-(3,4-Dihydroxyphenyl)lactic acid; Dan Shen Su; Dan shen suan A; DS 182; Salianic acid A; Salvianic acid A; Tanshinol. Grades: >98%. CAS No. 76822-21-4. Molecular formula: C9H10O5. Mole weight: 198.17. BOC Sciences 10
E7016 E7016 is an inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemo- and/or radiosensitizing activity. PARP inhibitor E7016 selectively binds to PARP and prevents PARP-mediated DNA repair of single strand DNA breaks via the base-excision repair pathway. This enhances the accumulation of DNA strand breaks and promotes genomic instability and eventually leads to apoptosis. In addition, this agent may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell resistance to chemotherapy and radiation therapy. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins that signal and recruit other proteins to repair damaged DNA and is activated by single-strand DNA breaks. Synonyms: E 7016; E-7016; 10-((4-Hydroxypiperidin-1-yl)methyl)chromeno[4,3,2-de]phthalazin-3(2H)-one. Grades: ≥98%. CAS No. 902128-92-1. Molecular formula: C20H19N3O3. Mole weight: 349.39. BOC Sciences 11
eSpCas9-N-NLS Nuclease eSpCas9-N-NLS Nuclease. Espcas9 nuclease is a mutant form of cas9 nuclease. compared with the wild type cas9 nuclease, espcas9 reduces off-target effects by over 10-fold, while maintaining robust on-target genome editing efficiency. genscript has developed a espcas9-n-nls nuclease which contains a nuclear localization sequence (nls) on the n-terminus of the protein to meet all the researchers requirements (e.g. in vitro cleavage assay, rnp complex transfection, and micro injection). Group: Cloning Enzymes. Purity: 100μg; 500μg. Storage: Store at -20 ?. Source: E.coli. Pack: 10 mM Tris, 300 mM NaCl, 0.1 mM EDTA, 1 mM DTT, 50% Glycerol pH7.4, at 25°C. Cat No: CE-3507. Creative Enzymes
Fas-activated serine/threonine kinase This enzyme is activated during Fas-mediated apoptosis. Following Fas ligation, the enzyme, which is constitutively phosphorylated, is dephosphorylated, and it is the dephosphorylated form that causes phosphorylation of TIA-1, a nuclear RNA-binding protein. Phosphorylation of TIA-1 precedes the onset of DNA fragmentation. Group: Enzymes. Synonyms: FAST; FASTK; STK10. Enzyme Commission Number: EC 2.7.11.8. CAS No. 170347-50-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3159; Fas-activated serine/threonine kinase; EC 2.7.11.8; 170347-50-9; FAST; FASTK; STK10. Cat No: EXWM-3159. Creative Enzymes
Genistein Cell-permeable, reversible, substrate competitive tyrosine kinase inhibitor (including EGFR phosphorylation), implicated in almost all cell growth and proliferation signal cascades. Inhibitor of mammalian DNA topoisomerase II. Anticancer agent, inducing cell cycle arrest and apoptosis. Antiangiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis. Binds estrogen receptor beta. Can increase the rate of growth of some ER expressing breast cancers. Potent alpha-glucosidase inhibitor. Anthelmintic. Anti-diabetic. Activates nuclear receptors, oestrogen receptors and peroxisome proliferator-activated receptors (all PPAR isoforms) and it inhibits various enzyme activities. Inhibitor of GLUT4-mediated glucose uptake in 3T3-L1 adipocytes. Stimulator of autophagy vacuolization. Antioxidant. TRAIL sensitizer. Acts as an agonist at the GPR30 receptor. DNA methyltransferase inhibitor. Genistein exhibits synergistic antibacterial effects on MRSA. Group: Biochemicals. Alternative Names: NSC 36586; Baichanin A; Differenol A; 4',5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 446-72-0. Pack Sizes: 10mg, 50mg, 250mg. Molecular Formula: C??H??O?. US Biological Life Sciences. USBiological 4
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Glyceraldehyde-3-phosphate dehydrogenase from Human, Recombinant Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a tetramer of 36 kDa subunits, is a catalytic enzyme involved in glycolysis. GAPDH catalyzes the reversible reduction of glyceraldehyde-3-phosphate to 3-phosphoglycerol phosphate in the presence of NAD+. Besides functioning as a glycolytic enzyme in the cytoplasm, mammalian GAPDH is also involved in a variety of intracellular processes such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. Glyceraldehyde-3-phosphate dehydrogenase was also found to bind to mutant polyglutamine proteins formed in neurodegenerative diseases such as Huntingto...horylating); triosephosphate dehydrogenase; dehydrogenase, glyceraldehyde phosphate; phosphoglyceraldehyde dehydrogenase; 3-phosphoglyceraldehyde dehydrogenase; NAD+-dependent glyceraldehyde phosphate dehydrogenase; glyceraldehyde phosphate dehydrogenase (NAD+); glyceraldehyde-3-phosphate dehydrogenase (NAD+); NADH-glyceraldehyde phosphate dehydrogenase; glyceraldehyde-3-P-dehydrogenase; 9001-50-7. Glyceraldehyde-3-phosphate Dehydrogenase. Mole weight: 37,984 Da. Activity: > 80 units/mg protein. Stability: Store at -20°C. Form: Lyophilized from a buffered solution with stabilizers. Source: E. coli. Species: Human. EC 1.2.1.12; GAPDH; glyceraldehyde-3-phosphate Creative Enzymes
IN01001 INO1001 is an isoindolinone derivative and potent inhibitor of the nuclear enzyme poly (ADP-ribose) polymerase (PARP) with chemosensitization and radiosensitization properties. It inhibits PARP and results in inhibition of tumor cell DNA repair mechanisms. It has tumor cell resistance and may be used to chemotherapy and radiation therapy. Uses: Ino1001 has tumor cell resistance and may be used to chemotherapy and radiation therapy. Synonyms: IN01001; IN 01001; IN-01001; N-(3-morpholin-4-ylpropyl)-5-oxo-6,11-dihydroindeno[1,2-c]isoquinoline-9-sulfonamide;INO-1001;5H-Indeno[1,2-c]isoquinoline-9-sulfonaMide, 6,11-dihydro-N-[3-(4-Morpholinyl)propyl]-5-oxo. Grades: 98%. CAS No. 501364-82-5. Molecular formula: C23H25N3O4S. Mole weight: 439.53. BOC Sciences 10
Iniparib BSI-201 is a small-molecule prodrug inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase-1 (PARP-1) with potential chemosensitizing, radiosensitizing and antineoplastic activities. In vivo, PARP-1 inhibitor BSI-201 is converted to the active drug, which selectively binds to PARP-1 and inhibits PARP-1- mediated DNA repair. Consequently, this agent may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell resistance to chemotherapy and radiation therapy. In addition, PARP-1 inhibitor BSI-201 may exhibit direct antineoplastic activity against cancers defective in DNA repair. PARP-1 catalyzes post-translational ADP-ribosylation of nuclear proteins and is activated by single-strand DNA (ssDNA) breaks. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: BSI-201; BSI201; BSI 201; NSC746045; NSC-746045; NSC 746045; ND-71677; NIBA; INO-2BA; SAR-240550; IND-71677. IND 71677; IND71677; Iniparib. Grades: 99.82%. CAS No. 160003-66-7. Molecular formula: C7H5IN2O3. Mole weight: 292.032. BOC Sciences 10
Jesaconitine Jesaconitine is a natural compound that has been shown to have anti-inflammatory properties. It has been shown to inhibit the activity of cyclooxygenase and lipoxygenase enzymes, which are involved in the production of prostaglandins. Jesaconitine also inhibits the expression of nuclear DNA and suppresses myeloma cells by inhibiting their ability to synthesize proteins. Jesaconitine has also been shown to inhibit chronic arthritis in animal models by suppressing inflammation and preventing joint damage. This compound is not active against nonsteroidal anti-inflammatory drugs such as ibuprofen, diclofenac, and naproxen. Jesaconitine can be extracted from the plant Angelica Dahurica or synthesized in laboratories. It is soluble in trifluoroacetic acid (TFA) and can be analyzed using nuclear magnetic resonance spectroscopy with high values for matrix effect and control analysis. Group: Other alkaloids. Alternative Names: Diesaconitine(1a,3a,6a,14a,15a,16b)-20-Ethyl-1,6,16-triMethoxy-4-(MethoxyMethyl)-aconitane-3,8,13,14,15-pentol 8-Acetate 14-(4-Meth oxybenzoate). CAS No. 16298-90-1. Molecular formula: C35H49NO12. Mole weight: 675.76 g/mol. Canonical SMILES: CCN1C[C@@]2 ([C@@H] (C[C@@H] ([C@@]34[C@@H]2[C@H] ([C@@H] ([C@H]31)[C@@]5 ([C@@H]6[C@H]4C[C@@] ([C@@H]6OC (=O)C7=CC=C (C=C7)OC) ([C@H] ([C@@H]5O)OC)O)OC (=O)C)OC)OC)O)COC. Catalog: ACM16298901. Alfa Chemistry.
Native Rabbit Pyruvate Kinase/Lactic Dehydrogenase enzymes Lactate dehydrogenase from rabbit muscle can be inhibited by ascorbate. Aldolase and actin were shown to block this inhibitory effect. Pyruvate kinase requires bivalent and monovalent cations such as Mg2+ and K+ respectively for activation to occur. Pyruvate kinase from rabbit muscle catalyzes an atp-dependent phosphorylation of glycolate to yield 2-phosphoglycolate. buffered aqueous glycerol solution, 900-1400 units/ml lactic dehydrogenase, 600-1 kda units/ml pyruvate kinase. Applications: Pyruvate kinase from rabbit muscle has been used in a study to assess nuclear magnetic relaxation studies of the conformation of adenosine 5?-triphosphate. it has also been used in a study to investigate heterogeneity of presumably homogeneous protein preparations. Group: Enzymes. Synonyms: Pyruvate Kinase/Lactic Dehydrogenase enzymes; PK/LDH enzymes. PK/LDH enzymes. Activity: 900-1400 units/mL lactic dehydrogenase; 600-1,000 units/mL pyruvate kinase. Stability: -20°C. Form: buffered aqueous glycerol solution. Source: rabbit muscle. Species: Rabbit. Pyruvate Kinase/Lactic Dehydrogenase enzymes; PK/LDH enzymes. Cat No: NATE-0568. Creative Enzymes
NLS-Cas9-EGFP Nuclease NLS-Cas9-EGFP Nuclease. Nls-cas9-egfp is a fusion protein contains a nuclear localization sequence (nls) on its n terminal and egfp on the c terminal. the egfp can be used as a reporter for tracking or sorting transfected cells, which enables the possibility of enriching cell populations for desired genome edits via fluorescence activated cell sorting (facs). it significantly reduces the labor and cost associated with single cell cloning and genotyping in genome editing applications. Group: Cloning Enzymes. Purity: 100μg; 500μg. Storage: Store at -20 ?. Source: E.coli. Pack: 10 mM Tris, 300 mM NaCl, 0.1 mM EDTA,1 mM DTT, 50% Glycerol PH7.4, at 25°C. Cat No: CE-3506. Creative Enzymes
NLS-Cas9-NLS Nuclease NLS-Cas9-NLS Nuclease. Nls-cas9-nls is produced by expression in an e. coli strain carrying a plasmid encoding the cas9 gene from streptococcus pyogenes with a double-ends nuclear localization signal (nls). it can be used for genome editing by inducing site-specific dna double stranded breaks. cas9 protein forms a very stable ribonucleoprotein (rnp) complex with the guide rna (grna) component of the crispr/cas9 system, which can localize to the nucleus immediately once entering the cell with the guide of the nls. compared with the mrna or plasmid systems, transcription and translation processes are not required. this dna-free system avoids the risk of inserting foreign dna into the genome, which can be quite useful for gene editing-based disease therapy. our highly pure and active cas9 nuclease meets all of the researcher´s requirements (e.g. in vitro cleavage assay, rnp complex transfection, micro injection). Group: Cloning Enzymes. Purity: 50μg; 100μg. Storage: Store at -20 ?. Source: E.coli. Pack: 10 mM Tris, 300 mM NaCl, 0.1 mM EDTA, 1 mM DTT, 50% Glycerol pH7.4 at 25?. Cat No: CE-3504. Creative Enzymes
N-Nitrosodiethylamine N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver. Uses: Scientific research. Group: Natural products. Alternative Names: Diethylnitrosamine; DEN. CAS No. 55-18-5. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N7434. MedChemExpress MCE
N-Nitrosodiethylamine-d10 N-Nitrosodiethylamine-d 10 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Diethylnitrosamine-d10; DEN-d10. CAS No. 1219794-54-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N7434S1. MedChemExpress MCE
NSC697923 NSC697923 is a cell-permeable and selective inhibitor of the Ub-conjugating enzyme (E2) complex Ubc13-Uev1A. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity. Synonyms: NSC 697923; NSC-697923; Furan, 2-[(4-methylphenyl)sulfonyl]-5-nitro-; 2-Nitro-5-(toluene-4-sulfonyl)-furan. Grades: >98%. CAS No. 343351-67-7. Molecular formula: C11H9NO5S. Mole weight: 267.26. BOC Sciences 11
nuclear-inclusion-a endopeptidase The potyviruses cause diseases in plants, and inclusion bodies appear in the host cell nuclei; protein a of the inclusion bodies is the endopeptidase. The enzyme finds practical use when encoded in vectors for the artificial expression of recombinant fusion proteins, since it can confer on them the capacity for autolytic cleavage. It is also reported that transgenic plants expressing the enzyme are resistant to viral infection. Type example of peptidase family C4. Group: Enzymes. Synonyms: potyvirus NIa protease. Enzyme Commission Number: EC 3.4.22.44. CAS No. 139946-51-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4219; nuclear-inclusion-a endopeptidase; EC 3.4.22.44; 139946-51-3; potyvirus NIa protease. Cat No: EXWM-4219. Creative Enzymes
nucleoplasmin ATPase An acidic nuclear protein that is active in the ATP-dependent assembly of nucleosome cores, in decondensation of sperm chromatin and in other histone-involving processes. Group: Enzymes. Enzyme Commission Number: EC 3.6.4.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4701; nucleoplasmin ATPase; EC 3.6.4.11. Cat No: EXWM-4701. Creative Enzymes
Olaparib Olaparib, also known as AZD-2281 or KU-59436, is a small-molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Olaparib selectively binds to and inhibits PARP, inhibiting PARP-mediated repair of single strand DNA breaks; PARP inhibition may enhance the cytotoxicity of DNA-damaging agents and may reverse tumor cell chemoresistance and radioresistance. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins and can be activated by single-stranded DNA breaks. Synonyms: AZD2281; AZD-2281; AZD 2281; KU59436; KU-59436; KU 59436; KU0059436; KU-0059436; KU 0059436; Olaparib. trade name Lynparza; 4-[[3-[4-(cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one. Grades: >98%. CAS No. 763113-22-0. Molecular formula: C24H23FN4O3. Mole weight: 434.471. BOC Sciences 8
PF-670462 PF-670462 is a potent and selective inhibitor of CK1ε in isolated enzyme preparations. It inhibits PER protein nuclear translocation causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo. It less effectively inhibits a wide variety of related or common kinases. It disrupts circadian rhythms in cells and animals and blocks the locomotor response to amphetamines in mice. It remains unclear whether one of the kinases has a predominant role in regulating the circadian clock. Synonyms: PF-670462; PF 670462; PF670462;PF-670462 HCl; PF-670462 hydrochloride. Grades: >98%. CAS No. 950912-80-8. Molecular formula: C19H22Cl2FN5. Mole weight: 410.32. BOC Sciences 9
phosphatidylinositol-4,5-bisphosphate 4-phosphatase Two pathways exist in mammalian cells to degrade 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [PtdIns(4,5)P2]. One is catalysed by this enzyme and the other by EC 3.1.3.36, phosphoinositide 5-phosphatase, where the product is PtdIns4P. The enzyme from human is specific for PtdIns(4,5)P2 as substrate, as it cannot use PtdIns(3,4,5)P3, PtdIns(3,4)P2, PtdIns(3,5)P2, PtdIns5P, PtdIns4P or PtdIns3P. In humans, the enzyme is localized to late endosomal/lysosomal membranes. It can control nuclear levels of PtdIns5P and thereby control p53-dependent apoptosis. Group: Enzymes. Synonyms: phosphatidylinositol-4,5-bisphosphate 4-phosphatase I; phosphatidylinositol-4,5-bisphosphate 4-phosphatase II; type I PtdIns-4,5-P2 4-Ptase; type II PtdIns-4,5-P2 . Enzyme Commission Number: EC 3.1.3.78. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3683; phosphatidylinositol-4,5-bisphosphate 4-phosphatase; EC 3.1.3.78; phosphatidylinositol-4,5-bisphosphate 4-phosphatase I; phosphatidylinositol-4,5-bisphosphate 4-phosphatase II; type I PtdIns-4,5-P2 4-Ptase; type II PtdIns-4,5-P2 4-Ptase; IpgD; PtdIns-4,5-P2 4-phosphatase type I; PtdIns-4,5-P2 4-phosphatase type II; type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase; type 1 4-phosphatase. Cat No: EXWM-3683. Creative Enzymes
Poly [ADP-ribose] polymerase 1 from Human, Recombinant PARP-1, a nuclear enzyme that synthesizes ADP-ribose polymers from NAD, specifically binds Zn2+ and DNA, and recognizes single-strand breaks in DNA. It is involved in base excision repair, both short-patch and long-patch, rejoining DNA strand breaks and plays a role in p53 expression and activation. A high level of basal neuronal DNA damage and PARP activity has been reported in rat brain tissue. PARP-1 was shown to be required for HIV-1 integration into DNA. If PARP-1 is deficient there is no productive HIV-1 infection. Applications: Parp-1 is a nuclear enzyme that synthesizes adp-ribose polymers from nad+, specifically binds zn2+ and dna, and recognizes single-st...enosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase; EC 2.4.2.30. Enzyme Commission Number: EC 2.4.2.30. CAS No. 58319-92-9. Poly [ADP-ribose] polymerase 1. Storage: -20°C. Form: Supplied as a solution in 20 mM Tris-HCl, pH 8.0, 200 mM NaCl, 1 mM DTT, 0.1% Triton(TM)-X 100, 50 % glycerol, and 0.1 mg/ml BSA. Source: E. coli. Species: Human. PARP1; poly (ADP-ribose) synthase; ADP-ribosyltransferase (polymerizing); NAD ADP-ribosyltransferase; PARP; PARP-1; NAD+:poly (adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase (incorrect); NAD+:poly (adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase; EC 2.4.2.30. Cat No: NATE-0507. Creative Enzymes
Poly(A) polymerase gamma (724-734) Poly(A) polymerase gamma (724-734) is a peptide corresponding to residues 724-734 of Poly(A) polymerase gamma. Poly(A) polymerase gamma is responsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA. Synonyms: PAP-gamma (724-734); Polynucleotide adenylyltransferase gamma (724-734); Signal recognition particle RNA-adenylating enzyme (724-734). BOC Sciences 3
protein farnesyltransferase This enzyme, along with protein geranylgeranyltransferase types I (EC 2.5.1.59) and II (EC 2.5.1.60), constitutes the protein prenyltransferase family of enzymes. Catalyses the formation of a thioether linkage between the C-1 of an isoprenyl group and a cysteine residue fourth from the C-terminus of the protein. These protein acceptors have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably serine, methionine, alanine or glutamine; leucine makes the protein a substrate for EC 2.5.1.59. The enzymes are relaxed in specificity for A1, but cannot act if A2 is aromatic. Substrates of the prenyltransferases include Ras, Rho, Rab, other Ras-related small GTP-binding proteins, γ-subunits of heterotrimeric G-proteins, nuclear lamins, centromeric proteins and many proteins involved in visual signal transduction. A zinc metalloenzyme that requires Mg2+ for activity. Group: Enzymes. Synonyms: FTase. Enzyme Commission Number: EC 2.5.1.58. CAS No. 131384-38-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2795; protein farnesyltransferase; EC 2.5.1.58; 131384-38-8; FTase. Cat No: EXWM-2795. Creative Enzymes
Rucaparib Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway. So, rucaparib has been also found to be most effective in cells deficient in DNA repair, where the cells deficient are caused by exposure to genotoxic agents, such as irradiation produces DNA damage and its toxicity is augmented when the DNA repair is impaired. Increased radiosensitivity in presence of rucaparib was associated with persistent DNA breaks as determined by gamma-H2AX and p53BP1 foci. Rucaparib radiosensitizes prostate cancer cells, most effectively those that are PTEN-deficient and are expressing ETS gene fusion proteins, which inhibits NHEJ DNA repair. Uses: Cancer therapy. Synonyms: 8-Fluoro-2-(4-((methylamino)methyl)phenyl)-1,3,4,5-tetrahydro-6H-azepino(5,4,3-cd)indol-6-one; Rucaparib free base, AG-14447; AG 14447; AG14447; Rubraca. Grades: >98%. CAS No. 283173-50-2. Molecular formula: C19H18FN3O. Mole weight: 323.36. BOC Sciences 9
SB 706375 SB 706375 is a high affinity and non-peptide antagonist of the mammalian urotensin-II (UT) receptor displaying ≥100-fold selectivity for the human UT receptor over 86 different receptors, ion channels, enzymes, transporters and nuclear hormones. SB 706375 also inhibits binding of radiolabeled urotensin to endogenous human UT receptors (Ki = 5.4 nM in a whole-cell binding assay). Synonyms: SB-706375; SB 706375; SB706375. 2-Bromo-4, 5-dimethoxy-N-[3-[[ (3R) -1-methyl-3-pyrrolidinyl]oxy]-4- (trifluoromethyl) phenyl]benzenesulfonamide. Grades: ≥98% by HPLC. CAS No. 733734-61-7. Molecular formula: C20H22BrF3N2O5S. Mole weight: 539.36. BOC Sciences 10
[Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase Skp1 is a cytoplasmic and nuclear protein required for the ubiquitination of cell cycle regulatory proteins and transcriptional factors. In Dictyostelium Skp1 is modified by the linear pentasaccharide Galα1-6Galα1-L-Fucα1-2Galβ1-3GlcNAc, which is attached to a hydroxyproline residue at position 143. This enzyme catalyses the first step in the building up of the pentasaccharide by attaching an N-acetylglucosaminyl group to the hydroxyproline residue. It requires dithiothreitol and a divalent cation for activity. Group: Enzymes. Synonyms: Skp1-HyPro GlcNAc-transferase; UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase; UDP-GlcNAc:Skp1-hydroxyproline GlcNAc. Enzyme Commission Number: EC 2.4.1.229. CAS No. 256531-81-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2458; [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase; EC 2.4.1.229; 256531-81-4; Skp1-HyPro GlcNAc-transferase; UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase; UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase; UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase; UDP-N-acetyl-D-glucosamine:[Skp1-protein]-hydroxyproline N-acetyl-D-glucosaminyl-transferase. Cat No: EXWM-2458. Creative Enzymes
small monomeric GTPase A family of about 50 enzymes with a molecular mass of 21 kDa that are distantly related to the α-subunit of heterotrimeric G-protein GTPase (EC 3.6.5.1). They are involved in cell-growth regulation (Ras subfamily), membrane vesicle traffic and uncoating (Rab and ARF subfamilies), nuclear protein import (Ran subfamily) and organization of the cytoskeleton (Rho and Rac subfamilies). Group: Enzymes. Enzyme Commission Number: EC 3.6.5.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4713; small monomeric GTPase; EC 3.6.5.2. Cat No: EXWM-4713. Creative Enzymes
Spautin-1 (6-fluoro-N- [4-fluorobenzyl] quinazolin-4-amine, Specific and Potent AUtophagy Inhibitor 1, C43, Autophagy Inhibitor II) A quinazolin compound that acts as a specific and potent inhibitor of autophagy and promotes Vps34 PI 3-kinase complex degradation by blocking the activity of USP 10 (IC50 = 580nM) and USP 13 (IC50 = 690nM) deubiquitinating enzymes. However, it does not affect the lipid kinase activity of Vps34. Also shown to reduce the level of cytoplasmic and nuclear p53. Sensitizes breast cancer cell lines (BCAP37, MCF-7, and BT549) to apoptosis under conditions of nutritional deprivation. Also shown to inhibit etoposide-induced cell death in Bax/Bak double knockout (DKO) cells. Normal cell lines (e.g., MDCK cells) do not undergo autophagy in the presence of Spautin-1. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
Stenoparib Stenoparib, also known as E7449 and 2X-121, is an orally available small molecule inhibitor of the nuclear enzymes poly (ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration, E7449 selectively binds to PARP 1 and 2, thereby preventing the repair of damaged DNA via the base excision repair (BER) pathway. This agent enhances the accumulation of single and double strand DNA breaks and promotes genomic instability eventually leading to apoptosis. PARP 1/2 inhibitor E7449 may enhance the cytotoxicity of DNA-damaging agents and of radiotherapy. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins that signal and recruit other proteins to repair damaged DNA. Group: Inhibitors. Alternative Names: E7449; E 7449; E-7449; 2X-121; 2X 121; 2X121; Stenoparib. CAS No. 1140964-99-3. Molecular formula: C18H15N5O. Mole weight: 317.34. Appearance: Solid powder. Purity: >98%. IUPACName: 8-(isoindolin-2-ylmethyl)-2H-pyridazino[3,4,5-de]quinazolin-3(9H)-one. Canonical SMILES: O=C1NN=C (N2)C3=C (C=CC=C31)N=C2CN (C4)CC5=C4C=CC=C5. Catalog: ACM1140964993. Alfa Chemistry.
Talazoparib Talazoparib, also known as BMN-673, is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity. BMN-673 selectively binds to PARP and prevents PARP-mediated DNA repair of single strand DNA breaks via the base-excision repair pathway. BMN-673 has been proven to be highly active in mouse models of human cancer and also appears to be more selectively cytotoxic with a longer half-life and better bioavailability as compared to other compounds in development. Uses: For research used only. Synonyms: BMN-673; LT-673. BMN 673; LT 673. BMN673; LT673. Grades: 98%. CAS No. 1207456-01-6. Molecular formula: C19H14F2N6O. Mole weight: 380.359. BOC Sciences 9
Tobacco Etch Virus Protease, Recombinant Recombinant TEV Protease is a site-specific protease purified from E. coli by the affinity tag, GST tag. The protease can be used for the removal of affinity tags from fusion proteins. The seven-amino-acid recognition site for TEV protease is Glu-Asn-Leu-Tyr-Phe-Gln-Gly with cleavage occurring between Gln and Gly. The optimal temperature for cleavage is 30°C; however, the enzyme can be used at temperatures as low as 4°C. Following digestion, TEV protease can be removed from the reaction via the GST tag sequence by affinity chromatography. Applications: A number of variables can be changed to optimize the cleavage of any specific protein. the amount of tev protease, the temperature of the incubation, and the time needed for cleavage may be examined. if the protein of interest is heat-labile, then 4°c incubations are recommended. reactions at 4°c will require longerincubation times and/or more tev protease. Group: Enzymes. Synonyms: TEV protease; Tobacco Etch Virus nuclear inclusion a endopeptidase; Tobacco Etch Virus Protease. Purity: >90% by SDS-PAGE. TEV Protease. Appearance: Clear colorless liquid. Storage: Store recombinant TEV protease at -70°C for long term or at -20°C for < 6 months. Source: E. coli. TEV protease; Tobacco Etch Virus nuclear inclusion a endopeptidase; Tobacco Etch Virus Protease. Cat No: NATE-0922. Creative Enzymes
tRNA pseudouridine13 synthase Pseudouridine synthase TruD from Escherichia coli specifically acts on uridine13 in tRNA. The Pus7 protein from Saccharomyces cerevisiae is a multisite-multisubstrate pseudouridine synthase that is able to modify uridine13 in several yeast tRNAs, uridine35 in the pre-tRNATyr, uridine35 in U2 small nuclear RNA, and uridine50 in 5S rRNA. Group: Enzymes. Synonyms: TruD; YgbO; tRNA PSI13 synthase; RNA:PSI-synthase Pus7p; Pus7p; RNA:pseudouridine-synthase Pus7p; Pus7 protein. Enzyme Commission Number: EC 5.4.99.27. CAS No. 430429-15-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5567; tRNA pseudouridine13 synthase; EC 5.4.99.27; 430429-15-5; TruD; YgbO; tRNA PSI13 synthase; RNA:PSI-synthase Pus7p; Pus7p; RNA:pseudouridine-synthase Pus7p; Pus7 protein. Cat No: EXWM-5567. Creative Enzymes
type II protein arginine methyltransferase The enzyme catalyses the methylation of one of the terminal guanidino nitrogen atoms in arginine residues within proteins, forming monomethylarginine, followed by the methylation of the second terminal nitrogen atom to form a symmetrical dimethylarginine. The mammalian enzyme is active in both the nucleus and the cytoplasm, and plays a role in the assembly of snRNP core particles by methylating certain small nuclear ribonucleoproteins. cf. EC 2.1.1.319, type I protein arginine methyltransferase, EC 2.1.1.321, type III protein arginine methyltransferase, and EC 2.1.1.322, type IV protein arginine methyltransferase. Group: Enzymes. Synonyms: PRMT5 (gene name); PRMT9 (gene name). Enzyme Commission Number: EC 2.1.1.320. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1928; type II protein arginine methyltransferase; EC 2.1.1.320; PRMT5 (gene name); PRMT9 (gene name). Cat No: EXWM-1928. Creative Enzymes
1,2,3-trimethylimidazolium methylsulfate 1,2,3-trimethylimidazolium methylsulfate. Uses: Metal plating, electropolishing, metal reprocessing, phase transfer media, batteries fuel cells, nanomaterials, industrial solvents, nuclear fuel red waste, enzymatic catalysis, lubricants heat transfer and solar energy conversion. Group: Electrolytes. CAS No. 65086-12-6. Product ID: methyl sulfate; 1,2,3-trimethylimidazol-1-ium. Molecular formula: 222.26. Mole weight: C7H14N2O4S. CC1=[N+](C=CN1C)C.COS(=O)(=O)[O-]. InChI=1S/C6H11N2. CH4O4S/c1-6-7(2)4-5-8(6)3; 1-5-6(2, 3)4/h4-5H, 1-3H3; 1H3, (H, 2, 3, 4)/q+1; /p-1. OUAUEIYYLHUEPK-UHFFFAOYSA-M. 98% min. Alfa Chemistry Materials 7
1,2,3-trimethylimidazolium trifluoromethanesulfonate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Heterocyclic organic compound. Alternative Names: 1,2,3-Trimethylimidazolium trifluoromethanesulfonate, Trifluoromethanesulfonic acid 1,2,3-Trimethylimidazolium salt, 05942_FLUKA, CTK8F2856, AG-L-62869, 439286-64-3. CAS No. 439286-64-3. Molecular formula: C7H11F3N2O3S. Mole weight: 260.23. Purity: 98% min. IUPACName: trifluoromethanesulfonate;1,2,3-trimethylimidazol-1-ium. Canonical SMILES: CC1=[N+](C=CN1C)C. C(F)(F)(F)S(=O)(=O)[O-]. Catalog: ACM439286643. Alfa Chemistry. 2
1,3-Diisopropylimidazolium Tetrafluoroborate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Heterocyclic organic compound. Alternative Names: 1,3-Diisopropyl-1H-imidazol-3-ium tetrafluoroborate. CAS No. 286014-34-4. Molecular formula: C9H17BF4N2. Mole weight: 240.05. Appearance: White to Brown crystal to powder. Purity: 96%+. IUPACName: 1,3-di(propan-2-yl)imidazol-1-ium;tetrafluoroborate. Canonical SMILES: [B-](F)(F)(F)F. CC(C)N1C=C[N+](=C1)C(C)C. Catalog: ACM286014344-2. Alfa Chemistry. 2
1,3-diMethylImidazolium Bromide Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Other ionic liquids. CAS No. 71027-57-1. Molecular formula: C5H11BrN2. Mole weight: 179.058. Purity: 98% min. Catalog: ACM71027571. Alfa Chemistry. 2
1,3-DIMETHYLIMIDAZOLIUM METHYLSULFATE 1,3-DIMETHYLIMIDAZOLIUM METHYLSULFATE. Uses: Metal plating, electropolishing, metal reprocessing, phase transfer media, batteries fuel cells, nanomaterials, industrial solvents, nuclear fuel red waste, enzymatic catalysis, lubricants heat transfer and solar energy conversion. Group: Battery materials. CAS No. 97345-90-9. Product ID: 1,3-dimethylimidazol-1-ium; methyl sulfate. Molecular formula: 208.24. Mole weight: C6H12N2O4S. CN1C=C[N+](=C1)C.COS(=O)(=O)[O-]. InChI=1S/C5H9N2. CH4O4S/c1-6-3-4-7(2)5-6; 1-5-6(2, 3)4/h3-5H, 1-2H3; 1H3, (H, 2, 3, 4)/q+1; /p-1. WOKQGMYCUGJNIJ-UHFFFAOYSA-M. 98% min. Alfa Chemistry Materials 7
1,3-DIMETHYLIMIDAZOLIUM METHYLSULFATE Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Heterocyclic organic compoundimidazolium ionic liquids. CAS No. 97345-90-9. Molecular formula: C6H12N2O4S. Mole weight: 208.24. Purity: 98% min. IUPACName: 1,3-dimethylimidazol-1-ium;methyl sulfate. Canonical SMILES: CN1C=C[N+](=C1)C.COS(=O)(=O)[O-]. Catalog: ACM97345909. Alfa Chemistry. 2
1,3-diMethylImidazolium Nitrate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Heterocyclic organic compound. CAS No. 941584-21-0. Molecular formula: C5H9N2.NO3. Mole weight: 159.14. Purity: 98% min. Catalog: ACM941584210. Alfa Chemistry. 2
1,3-diMethylImidazolium perchlorate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Other ionic liquids. CAS No. 77381-68-1. Molecular formula: C5H9N2.ClO4. Mole weight: 198.6. Purity: 98% min. Catalog: ACM77381681. Alfa Chemistry. 2
1,3-dimethylimidazolium tetrafluoroborate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Imidazolium ionic liquids. CAS No. 121091-31-4. Molecular formula: C5H9N2BF4. Mole weight: 183.94. Purity: ≥98%. Catalog: ACM121091314. Alfa Chemistry. 2
1,3-diMethylImidazolium triFluoroAcetate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Other ionic liquids. CAS No. 174899-93-5. Molecular formula: C5H9N2.C2F3O2. Purity: 98% min. Catalog: ACM174899935. Alfa Chemistry. 2
1,3-dimethylimidazolium trifluoromethanesulfonate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Imidazolium ionic liquids. CAS No. 121091-30-3. Molecular formula: C6H9F3N2O3S. Mole weight: 246.21. Purity: ≥98%. Catalog: ACM121091303. Alfa Chemistry. 2
1-(9-chloromethyl anthracene)-3-methylimidazolium chloride Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Functionized ionic liquids. CAS No. 61865-02-9. Molecular formula: C19H17N2.Cl. Mole weight: 310.821. Purity: 98% min. Catalog: ACM61865029. Alfa Chemistry. 2
1-Allyl-3-vinylimidazolium bromide Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Imidazolium ionic liquids. CAS No. 1072788-73-8. Molecular formula: C8H11N2Br. Mole weight: 215.0903. Purity: ≥98%. Catalog: ACM1072788738. Alfa Chemistry. 2
1-Allyl-3-vinylimidazolium chloride Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Imidazolium ionic liquids. CAS No. 100894-64-2. Molecular formula: C8H11N2Cl. Mole weight: 170.6393. Purity: ≥98%. Catalog: ACM100894642. Alfa Chemistry. 2
1-Allyl-3-vinylimidazolium tetrafluoroborate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Imidazolium ionic liquids. CAS No. 936030-54-5. Molecular formula: C8H11N2BF4. Mole weight: 221.9909. Purity: ≥98%. Catalog: ACM936030545. Alfa Chemistry. 2
1-benzyl-2,3-methylimidazolium bromide Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Functionized ionic liquids. CAS No. 862999-80-2. Molecular formula: C12H15BrN2. Mole weight: 267.165. Purity: 98% min. Catalog: ACM862999802. Alfa Chemistry. 2
1-benzyl-2,3-methylimidazolium chloride Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Functionized ionic liquids. CAS No. 36443-79-5. Purity: 98% min. Catalog: ACM36443795. Alfa Chemistry. 2
1-benzyl-2,3-methylimidazolium tetrafluoroborate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Functionized ionic liquids. CAS No. 862999-75-5. Purity: 98% min. Catalog: ACM862999755. Alfa Chemistry. 2
1-Benzyl-3-methylimidazolium Hexafluorophosphate 1-Benzyl-3-methylimidazolium Hexafluorophosphate. Uses: Metal plating, electropolishing, metal reprocessing, phase transfer media, batteries fuel cells, nanomaterials, industrial solvents, nuclear fuel red waste, enzymatic catalysis, lubricants heat transfer and solar energy conversion. Group: Electrolytesbattery materials. Alternative Names: BenyMIM PF6. CAS No. 433337-11-2. Product ID: 1-benzyl-3-methylimidazol-3-ium; hexafluorophosphate. Molecular formula: 318.20. Mole weight: C11H13F6N2P. C[N+]1=CN(C=C1)CC2=CC=CC=C2. F[P-](F)(F)(F)(F)F. 1S/C11H13N2. F6P/c1-12-7-8-13 (10-12)9-11-5-3-2-4-6-11; 1-7 (2, 3, 4, 5)6/h2-8, 10H, 9H2, 1H3; /q+1; -1. VVCQOUQQPZPIKL-UHFFFAOYSA-N. >98.0%(HPLC)(N). Alfa Chemistry Materials 7
1-Benzyl-3-methylimidazolium Hexafluorophosphate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Heterocyclic organic compoundfunctionized ionic liquids. Alternative Names: BenyMIM PF6. CAS No. 433337-11-2. Molecular formula: C11H13F6N2P. Mole weight: 318.2. Appearance: White to Light yellow powder to crystal. Purity: >98.0%(HPLC)(N). IUPACName: 1-benzyl-3-methylimidazol-3-ium;hexafluorophosphate. Canonical SMILES: C[N+]1=CN(C=C1)CC2=CC=CC=C2. F[P-](F)(F)(F)(F)F. Catalog: ACM433337112. Alfa Chemistry. 2
1-benzyl-3-methylimidazolium hydrogen sulfate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Other ionic liquids. CAS No. 956597-95-8. Purity: 98% min. Catalog: ACM956597958. Alfa Chemistry. 2
1-Benzyl-3-methylimidazolium methanesulfonate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Other ionic liquids. CAS No. 936014-36-7. Purity: 98% min. Catalog: ACM936014367. Alfa Chemistry. 2
1-benzyl-3-methylimidazolium tosylate Metal Plating, Electropolishing, Metal Reprocessing, Phase transfer media, Batteries Fuel Cells, Nanomaterials, Industrial Solvents, Nuclear Fuel Red Waste, Enzymatic Catalysis, Lubricants Heat Transfer and Solar Energy Conversion. Group: Functionized ionic liquids. CAS No. 52461-83-3. Molecular formula: C18H20N2O3S. Mole weight: 344.428. Purity: ≥98%. Catalog: ACM52461833. Alfa Chemistry. 2

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