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Deoxyribonucleic acids, known as DNA, assuming a paramount significance within the biomedical industry owing to their indispensable role in genetic inquiry, diagnostics and therapeutics. DNA remarkably contributes to comprehending and studying afflictions like cancer, hereditary disorders and contagious ailments. These remarkable biomolecules serve as imperative instruments in discerning genetic disparities, exploring gene expression intricacies and fostering tailored remedial approaches. Synonyms: Nucleic acids, deoxyribo-; Nucleic acids; Deoxyribonucleic acid; DNAs; DNA (06C, 14C, 15C, 16C). CAS No. 9007-49-2.
Deoxyribonucleic acids, salmon sperm (10C)
Salmon sperm deoxyribonucleic acids, denoted as 10C, are meticulously derived from salmon spermatozoa. Eminent for their immense potential in genetic investigation, encompassing DNA extraction, cloning, and PCR amplification, these nucleic acids also demonstrate indispensability in diagnosing genetic ailments and facilitating sundry molecular biology methodologies. Synonyms: Deoxyribonucleic acids, salmon sperm. CAS No. 68938-01-2.
10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite, an activator for viral RNA replication, is a specialized reagent used in the synthesis of modified oligonucleotides, particularly in the context of creating conjugated or functionalized nucleic acids. This reagent is particularly useful in the development of oligonucleotide-based drugs, where conjugation with lipophilic molecules like cholesterol can significantly improve the drug's performance. Synonyms: 5'-Cholesterol-TEG-CE Phosphoramidite; 10-O-[1-Propyl-3-N-carbamoylcholesteryl]-triethyleneglycol-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Cholest-5-en-3-ol (3β)-, 3-[16-[bis(1-methylethyl)amino]-19-cyano-6,9,12,15,17-pentaoxa-2-aza-16-phosphanonadecanoate]; 5'-Cholesteryl TEG phosphoramidite. Grade: ≥95%. CAS No. 1325147-19-0. Molecular formula: C46H82N3O7P. Mole weight: 820.13.
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 60ul. US Biological Life Sciences.
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11-dATP (Biotin) (Biotin-11-dATP)
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Alternative Names: g-[N-(Biotin-6-amino-hexanoyl)]-7-propargylamino-2-deoxy-7-deaza-adenosine-5-triphosphate, Triethylammonium Salt. Grades: Highly Purified. Pack Sizes: 10ul. US Biological Life Sciences.
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11-dCTP (Biotin)
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Alternative Names: γ-[N-(Biotin-6-amino-hexanoyl)]-5-propargylamino-2-deoxy-cytidine-5-triphosphate, Triethylammonium Salt. Grades: Highly Purified. CAS No. 136632-30-9. Pack Sizes: 200ul, 5x200ul. Molecular Formula: C28H44N7O16P3S, Molecular Weight: 859.67. US Biological Life Sciences.
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25ul, 5x25ul. US Biological Life Sciences.
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11-dUTP (Biotin) (5mM)
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Alternative Names: g-[N-(Biotin-6-amino-hexanoyl)]-5-aminoallyl-2-deoxy-uridine-5-triphosphate, Triethylammonium Salt. Grades: Highly Purified. Pack Sizes: 1ml. US Biological Life Sciences.
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 200ul. US Biological Life Sciences.
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 60ul. US Biological Life Sciences.
Worldwide
1,2,3,4,6-Penta-O-trimethylsilyl-D-glucopyranose
The chemical compound, 1,2,3,4,6-Penta-O-trimethylsilyl-D-glucopyranose, plays a pivotal role as a chemical reagent in the pharmaceutical and biotech industries. Its varied synthesis usage in the creation of nucleosides, peptides, and oligonucleotides reflects its significance in the development of drugs intended to treat and combat nucleic acid-related disorders, such as DNA and RNA implicated ailments. Synonyms: 1,2,3,4,6-Pentakis-O-(trimethylsilyl)-D-glucopyranose; 1,2,3,4,6-Penta-trimethylsilyl Glucopyranose; trimethyl-[[(2R,3R,4S,5R)-3,4,5,6-tetrakis(trimethylsilyloxy)oxan-2-yl]methoxy]silane; D-Glucopyranose, 5TMS. CAS No. 19126-99-9. Molecular formula: C21H52O6Si5. Mole weight: 541.07.
1,2,3,5-Tetra-O-acetyl-L-arabinofuranose
1,2,3,5-Tetra-O-acetyl-L-arabinofuranose is a quintessential precursor in the synthesis of potent antiviral pharmacologics. Its salient role includes versatile adaptability into nucleic acid analogs, facilitating targeted disease research. Synonyms: 1,2,3,5-Tetra-O-acetyl-L-arabinofuranose; 56272-01-6; SCHEMBL7034253; DTXSID201281619; L-Arabinofuranose, 1,2,3,5-tetraacetate. CAS No. 56272-01-6. Molecular formula: C13H18O9. Mole weight: 318.28.
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)uracil (2'-FANA-U) is a uracil nucleoside analogue. In the field of biomedicine, it's used in research of antiviral therapies as it interferes with nucleic acid synthesis, specifically targeting Hepatitis C and other viral infections. Grade: ≥ 97%.
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-β-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is used in the solid-phase synthesis of modified oligonucleotides. The modifications enhance the stability and binding affinity of the oligonucleotides. These modified nucleotides are valuable in various applications, including the development of antisense oligonucleotides, siRNA, and other therapeutic nucleic acids, as well as in research settings where enhanced stability and specific interactions are required. Synonyms: 5'-O-dimethoxytrityl-2'-deoxy-2'-fluoroarabinothymidine-3'-[(2-cyanoethyl)-(N,N-diisopropropyl)]-Phosphoramidite; 2'-F-ANA-T-3'-CE-Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine-3'-CED-phosphoramidite; 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 2'-Deoxy-2'-fluoro-5-Me-ara-U-3'-CED-phosphoramidite. Grade: 97%. CAS No. 208193-48-0. Molecular formula: C40H48FN4O8P. Mole weight: 762.82.
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite is a highly specialized phosphoramidite compound, extensively utilized in nucleic acid synthesis. This intriguing molecule finds widespread application in the realm of biomedicine, particularly for designing therapeutics tailored to combat specific ailments. Grade: 95%. Molecular formula: C39H46FN4O8P. Mole weight: 748.80.
1-(2'-Deoxy-5'-O-DMT-3'-O-nitrophenylsulphonyl-b-D-lyxofuranosyl)thymine is a biochemical reagent used mainly in genetic research. It's typically used in nucleic acid synthesis and can be a component in pharmaceuticals designed to target genetic diseases or disorders. Synonyms: 1-5[5-O-(4,4'-Dimethoxytrityl)-3-O-nitrophenylsulphonyl-2-deoxy-b-D-lyxofuranosyl]thymine; 5'-O-DMT-nosyl-lyxothymidine. Grade: 95%. CAS No. 444717-20-8. Molecular formula: C37H35N3O11S. Mole weight: 729.75.
1-((2R,3R,4R,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, a powerful antimicrobial agent, is renowned for its efficacy in treating a range of bacterial and fungal infections, including those caused by Candida, Aspergillus, and Cryptococcus species. This pharmaceutical marvel works by clobbering the synthesis of crucial nucleic acids in microbes to sabotage their survival. Notably, its phenomenal antibacterial and antifungal activity renders it an essential tool in the battle against streptococcal and staphylococcal infections. Synonyms: Sofosbuvir impurity SA15432. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 25952-53-8. Pack Sizes: 5 g; 10 g. Product ID: HY-D0178.
1,4-Dicyanonaphthalene
1,4-Dicyanonaphthalene is used in biological studies as electron transfer mechanism of nucleic acid precursors and ctDNA with protein enzymes and several fluorescence probes in both static and excited states. Group: Biochemicals. Grades: Highly Purified. CAS No. 3029-30-9. Pack Sizes: 2.5g, 5g. Molecular Formula: C12H6N2, Molecular Weight: 178.19. US Biological Life Sciences.
1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(uracil-1-yl)-D-altro-hexitol, a remarkable biomedical innovation, stands at the forefront of combating viral infections. Leveraging its exceptional potency, it exclusively targets and obstructs viral replication by precisely zeroing in on the nucleic acid synthesis-associated viral enzymes. Its unparalleled success reverberates through the treatment of diverse viral diseases, encompassing the likes of herpes and HIV. CAS No. 215959-64-1. Molecular formula: C24H22N2O7. Mole weight: 450.45.
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 200ul. US Biological Life Sciences.
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16-dUTP (Biotin) g-[N-(Biotin-6-amino-hexanoyl-6-aminobutanoyl)]-5-(3-aminoallyl)-2-deoxy-uridine-5- triphosphate, Triethylammonium Salt
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 200ul. US Biological Life Sciences.
Worldwide
16-UTP (Biotin) (g-[N-(Biotin-6-amino-hexanoyl-6-aminobutanoyl)]-5-(3-aminoallyl)-uridine-5- Triphosphate, Triethylammonium Salt
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 60ul. US Biological Life Sciences.
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18:0 mPEG2000 PE sodium
18:0 mPEG2000 PE sodium can be used for the preparation of stabilized nucleic acid-lipid particllipid particles (SNALPs). SNALPs represent some of the earliest and best functional siRNA-ABC nanoparticles described [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium. CAS No. 247925-28-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112760.
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 60ul. US Biological Life Sciences.
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 200ul. US Biological Life Sciences.
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1ml. US Biological Life Sciences.
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 60ul. US Biological Life Sciences.
Worldwide
1-Acetyl-2-deoxy-3,5-di-O-benzoylribofuranose
1-Acetyl-2-deoxy-3,5-di-O-benzoylribofuranose, a pivotal molecule in the realm of biomedicine, emerges as an indispensable ingredient for constructing nucleotide analogues, encompassing antiviral remedies and anticancer compounds. Noteworthy is its distinctive architecture that readily undergoes alteration and integration into nucleic acids, thereby serving as a priceless asset for scrutinizing DNA and RNA. Synonyms: 2-Deoxy-D-erythro-pentofuranose 1-acetate 3,5-dibenzoate. CAS No. 51255-12-0. Molecular formula: C21H20O7. Mole weight: 384.38.
1-(b-D-2-Deoxyribofuranosyl)-5-nitroindole
1-(b-D-2-Deoxyribofuranosyl)-5-nitroindole is a synthesized analog of nucleoside, typically finding its applications in the sphere of biomedical investigations. It can be employed to dissect the complexities of gene alteration, DNA replication or nucleic acid-drug interactions, its healing potential spans a myriad of diseases, notably encompassing cancerous afflictions and viral onslaughts. Synonyms: 1-(2-Deoxy-b-D-ribofuranosyl)-5-nitroindole; 1-(2-Deoxy-beta-D-ribofuranosyl)-5-nitro-1H-indole; (2R,3S,5R)-2-(hydroxymethyl)-5-(5-nitro-1H-indol-1-yl)tetrahydrofuran-3-ol. Grade: ≥95%. CAS No. 191421-10-0. Molecular formula: C13H14N2O5. Mole weight: 278.26.
1-(b-D-Xylofuranosyl)-5-fluorouracil
1-(b-D-Xylofuranosyl)-5-fluorouracil, also known as Xeloda, is an influential antineoplastic agent used to combat a diverse array of solid tumors and gastrointestinal cancers. Its mechanism of action is to thwart the synthesis of nucleic acids which in turn, allows for the complete nullification of cancer cell development. Synonyms: 1-(beta-D-Xylofuranosyl)-5-fluorouracil; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 5-Fluoro-1-(β-D-xylofuranosyl)-uracil; 5-Fluoro-1-(β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione. Grade: ≥95%. Molecular formula: C9H11FN2O6. Mole weight: 262.19.
1-β-D-Lyxofuranosylcytosine
1-β-D-Lyxofuranosylcytosine is a nucleoside analog where a cytosine base is linked to a β-D-lyxofuranose sugar. Unlike the standard β-D-ribose in natural nucleosides, the lyxofuranose sugar has a different stereochemistry, which can influence its biological interactions. This compound is of interest in medicinal chemistry and biochemical research, where its unique structure may contribute to modified activity or specificity in nucleic acid-related processes, such as enzyme interactions or antiviral applications. Synonyms: Cytarabine impurity 4; 4-Amino-1-β-D-lyxofuranosyl-2(1H)-pyrimidinone; 1-beta-D-Lyxofuranosyl cytosine. Grade: ≥95%. CAS No. 18265-49-1. Molecular formula: C9H13N3O5. Mole weight: 243.22.
Chlorodeoxyribocytidine, known for its antiviral and anticancer properties, has found its use in treating chronic hepatitis B and C as well as several cancer types. Its mechanism of action is attributed to the suppression of viral DNA replication and neoplastic cell proliferation by disrupting nucleic acid biosynthesis. The nucleoside analog serves as a potential candidate for managing tumorigenesis and viral infections.
1-Deaza-6-deamino-6-(thiophen-2-yl)-2'-deoxyadenosine is a modified nucleoside where the adenine base undergoes multiple structural changes. The 1-deaza modification replaces the nitrogen at position 1 of the adenine base with a carbon, while the 6-position is deaminated, removing the amino group. Additionally, a thiophen-2-yl group is introduced at the 6-position, and the nucleoside is further modified with a 2'-deoxy sugar, lacking the 2'-hydroxyl group. These modifications alter the nucleoside's properties, potentially enhancing its stability, altering its interaction with enzymes, and making it useful in nucleic acid-based applications like synthetic oligonucleotide design or research on nucleoside analogs for therapeutic purposes. Synonyms: 3-(2-Deoxy-β-D-erythro-pentofuranosyl)-7-(2-thienyl)-3H-imidazo[4,5-b]pyridine; 2'-Deoxyribo-7-(2-thienyl)-imidazo[4,5-b]pyridine; 7-(2-Thienyl)-3-(2-deoxy-β-D-ribofuranosyl)-3H-imidazo[4,5-b]pyridine. Grade: ≥95%. CAS No. 901130-20-9. Molecular formula: C15H15N3O3S. Mole weight: 317.36.
1-Me-dA-CE Phosphoramidite
1-Me-dA-CE Phosphoramidite, an essential resource in the realm of biomedical research, holds particular significance in the field of DNA synthesis and modification. Its primary purpose lies in integrating 1-Methyladenine (1-Me-dA) modifications into nucleic acid sequences. Its unblemished purity and adaptability to diverse synthesizers empower scientists to effectuate meticulous modifications, fueling the investigation of DNA-protein interactions, epigenetics, and DNA repair mechanisms. Synonyms: 5'-Monomethoxytrityl-N6-chloroacetyl-1-methyl-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-[9-[3-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5-O-(4-methoxytrityl)-2-deoxy-beta-D-ribofuranosyl]-1-methyl-1,6-dihydro-9H-purine-6-ylidene]chloroacetamide. Molecular formula: C42H49ClN7O6P. Mole weight: 814.31.
[2- (2-Aminoethoxy) ethoxy]acetic Acid
[2- (2-Aminoethoxy) ethoxy]acetic Acid is used in the development of chemically modified peptide nucleic acid (PNA) as a probe for qualitative and quantitative detection of DNA. It is also used in the preparation and studies of the biological activities of kappa agonist CovX-bodies. Group: Biochemicals. Grades: Highly Purified. CAS No. 134978-97-5. Pack Sizes: 250mg, 500mg. Molecular Formula: C6H13NO4, Molecular Weight: 163.169999999999. US Biological Life Sciences.
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2,2'-Anhydro-5-methyluridine
2,2'-Anhydro-5-methyluridine is a chemically modified nucleoside derivative of uridine, where the 2' hydroxyl group of the ribose is linked to the 2-position of the uracil ring, forming an anhydro bond. Additionally, the uracil base is methylated at the 5-position. This modification alters the nucleoside's properties, making it useful in biochemical and pharmacological research, particularly in studies focused on nucleic acid chemistry and potential therapeutic applications. Synonyms: O-2,2'-Anhydro-5-methyluridine; 2,2'-Anhydro-5-methyl-D-uridine; 2,2'-Anhydro-(1-b-D-arabinofuranosyl)-5-methyluracil; 2,2'-Anhydro-D-thymidine; 2,2'-Anhydro-5-methyluridine; (2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one; 2,2'-Anhydro-1-beta-arabinofuranosylthymine. Grade: ≥95%. CAS No. 22423-26-3. Molecular formula: C10H12N2O5. Mole weight: 240.21.
2',2'-Difluoro-2'-deoxyuridine 3',5'-Dibenzoate
2',2'-Difluoro-2'-deoxyuridine 3',5'-dibenzoate is a modified nucleoside derivative where the 2'-hydroxyl group of deoxyuridine is replaced by difluoromethylene (-CF2-) and the 3' and 5' positions of the sugar moiety are esterified with dibenzoate groups. This modification enhances the stability and alters the chemical properties of the nucleoside, making it useful in nucleic acid chemistry for applications such as nucleotide analog synthesis and structural studies. Synonyms: 3',5'-Dibenzoate-2',2'-Difluoro-2'-deoxyuridine; 3,5-Dibenzoate-2,2-difluorouridine; 3',5'-Di-O-benzoyl-2'-deoxy-2',2'-difluorouridine; Uridine, 2'-deoxy-2',2'-difluoro-, 3',5'-dibenzoate; ((2R,3R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4,4-difluorotetrahydrofuran-2-yl)methyl benzoate. Grade: ≥98%. CAS No. 143157-27-1. Molecular formula: C23H18F2N2O7. Mole weight: 472.39.
2',3',5'-Tri-O-acetyl Guanosine
2',3',5'-Tri-O-acetyl guanosine is a chemical compound commonly used in organic synthesis and nucleic acid chemistry. It features acetyl groups attached to the 2', 3', and 5' positions of the guanosine molecule. This modification serves to protect the reactive hydroxyl groups of guanosine, allowing for precise control over chemical reactions involving the nucleoside. It is often employed as a building block in the synthesis of modified nucleosides, nucleotides, and oligonucleotides for various research and biotechnological applications, including RNA interference, gene expression modulation, and pharmaceutical development. Synonyms: 2',3',5'-Triacetylguanosine; Guanosine 2',3',5'-triacetate; Guanosine Triacetate; NSC 66387; Triacetylguanosine. Grade: ≥98%. CAS No. 6979-94-8. Molecular formula: C16H19N5O8. Mole weight: 409.35.
2',3',5'-Tri-O-benzoyl-5-iodouridine
2',3',5'-Tri-O-benzoyl-5-iodouridine, a powerful antiviral agent, is utilized in the management of diverse viral infections. This potent compound hinders the viral DNA and RNA synthesis via interfering with its replication, as it incorporates into the viral nucleic acid. Its antiviral properties have been studied and numerous promising results have been reported, especially in influenza A virus and herpes simplex virus. Its low toxicity and high specificity make it a leading candidate for further clinical development as an innovative antiviral drug with great potential. Synonyms: O2',O3',O5'-tribenzoyl-5-iodo-uridine; 2'-O,3'-O,5'-O-Tribenzoyl-5-iodouridine; (2R,3R,4R,5R)-2-((benzoyloxy)methyl)-5-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate. Grade: ≥95%. CAS No. 2880-91-3. Molecular formula: C30H23IN2O9. Mole weight: 682.42.
2,3,5-Tri-O-p-chlorobenzoyl-b-D-ribofuranosyl chloride, a chemical entity involved in the synthesis of nucleoside analogues, exhibits remarkable efficacy in managing viral afflictions and oncogenic growth. The profound bioactivity of this compound is induced by its propensity to integrate with nucleic acids impeding their proliferation. Its indispensability in the development of antiviral and anticancer medications marks it as a crucial pharmaceutical component. Synonyms: Chloro-2,3,5-tri-O-p-chlorobenzoyl-b-D-ribofuranoside. Molecular formula: C26H18Cl4O7. Mole weight: 584.23.
2',3'-ddC frits column (100nmol)
The 2',3'-ddC frits column (100nmol) - a superior and reliable column that serves as a high-performance liquid chromatography (HPLC) tool. Its function is to accurately separate nucleoside analog drugs, enabling the biomedicine industry to detect and quantify 2',3'-dideoxycytidine (ddC) and its metabolites, vital in the treatment of HIV/AIDS. Whether for drug discovery or quality control purposes, this frits column from nucleic acid isolation stands firm as an essential and highly advantageous component. Synonyms: 2',3'-ddC frits column.
2',3'-ddG-CE Phosphoramidite
2',3'-ddG-CE Phosphoramidite is a key product used in the synthesis of modified nucleic acids for biomedical research. Specifically, it is used to introduce 2',3'-dideoxyguanosine (ddG) modifications into DNA or RNA strands. These modified nucleotides are useful in studying nucleic acid structure and function, as well as in developing new therapeutic approaches for diseases such as cancer and viral infections. Synonyms: N2-dimethylaminomethylidene-2',3'-dideoxyGuanosine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C22H35N8O4P. Mole weight: 506.54.
2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer), lithium salt
2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer), lithium salt, an indispensable constituent within the biomedical field, presents its prominence. Its application revolves around nucleic acids synthesis and DNA sequencing. This unique product is exclusively tailored for diligent scientists dedicated to drug investigation, primarily exploring the impact of diverse pharmaceuticals on ailments like cancer, HIV, alongside other viral afflictions. Molecular formula: C8H14N3O12P3S. Mole weight: 469.19.
2`,3`-Dideoxy-5`-guanylic Acid
2`,3`-Dideoxy-5`-guanylic Acid is a component used in pyrophosphorolysis activated polymerization applied to allele-specific amplification and nucleic acid sequence detection. Group: Biochemicals. Grades: Highly Purified. CAS No. 85956-71-4. Pack Sizes: 25mg, 100mg. Molecular Formula: C10H14N5O6P, Molecular Weight: 331.22. US Biological Life Sciences.
Worldwide
2',3'-Di-O-methylguanosine
2',3'-Di-O-methylguanosine, a remarkable biomedicine, takes center stage in the exploration and innovation of antiviral therapeutics, combating an array of viral afflictions. Its indispensability arises from its pivotal contribution to nucleic acid synthesis, with a particularly noteworthy involvement in the assembly of messenger RNA (mRNA) entities. By unraveling the intricate intricacies of viral replication and advancing novel curative measures, this product unfurls new vistas for scientific inquiry and medical breakthroughs. Molecular formula: C12H17N5O5. Mole weight: 311.30.
23-Monoketo Rifabutin
23-Monoketo Rifabutin is an impurity of Rifabutin (R505000), a semisynthetic derivative of Rifamycin S that inhibits nucleic acid synthesis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C46H58N4O11, Molecular Weight: 842.97. US Biological Life Sciences.
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2', 3'-O-Isopropyl ideneguanosine
A useful precursor for the preparation of nucleic acids. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences.
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2',3'-O-Isopropylideneinosine
An inosine derivative as antiviral, bactericidal, and antitumor agent for immunopotentiating uses. A useful precursor for the preparation of nucleic acids. Group: Biochemicals. Grades: Highly Purified. CAS No. 2140-11-6. Pack Sizes: 10g, 25g, 50g, 100g. Molecular Formula: C??H??N?O?, Melting Point: 263-272°C. US Biological Life Sciences.
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2',3'-O-Isopropylideneuridine
A useful precursor for the preparation of nucleic acids. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences.
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2',3'-O-Isopropylideneuridine
A useful precursor for the preparation of nucleic acids. Uses: A useful precursor for the preparation of nucleic acids. Synonyms: 1-((3AR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione; Uridine 2',3'-isopropylidine; Uridine 2',3'-acetonide; Uridine, 2',3'-O-(1-methylethylidene)-; Uridine, 2',3'-O-isopropylidene-; 2',3'-Isopropylideneuridine; 2',3'-O-(1-Methylethylidene)uridine; NSC 520038. Grade: 98%. CAS No. 362-43-6. Molecular formula: C12H16N2O6. Mole weight: 284.27.
2'/3'-O-(N-Methylanthraniloyl)-N6-methyl-adenosine-5'-triphosphate triethylammonium salt
2'/3'-O-(N-Methylanthraniloyl)-N6-methyl-adenosine-5'-triphosphate triethylammonium salt, a vital constituent in biomedical research, exhibits remarkable applications as a fluorescent probe for investigating functional nucleic acids, their interactions, and enzymatic activities. Moreover, it serves as a valuable tool in comprehending RNA dynamics, RNA-protein interactions, and RNA modifications alongside regulatory processes. Its versatility extends to potential therapeutic interventions for an array of ailments, encompassing cancer and neurological disorders. Molecular formula: C19H25N6O14P3·xC6H16N. Mole weight: 654.36 (free acid).
2,4,5-Triamino-6-pyrimidinol-13C2,15N
2,4,5-Triamino-6-pyrimidinol-13C2,15N is an intermediate in the synthesis of labelled Guanine (G836000). Guanine is on one of the five nucleobases incorporated into biological nucleic acids. Guanine, along with adenine and cytosine, is present in both DNA and RNA, whereas thymine is usually seen only in DNA, and uracil only in RNA. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C213C2H7N415NO. US Biological Life Sciences.
2-(4-Bromophenyl)-1-methyl-5-nitro-1H-benzo[d]imidazole has been used in the study of 5-nitrofuran derivatives as an inhibitor of nucleic acid and protein synthesis in Ehrlich ascites tumor cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 20648-12-8. Pack Sizes: 1g, 2.5g. Molecular Formula: C14H10BrN3O2, Molecular Weight: 332.15. US Biological Life Sciences.
2-(4-Bromophenyl)-1-methyl-d3-5-nitro-1H-benzo[d]imidazole is the labeled analogue of 2-(4-Bromophenyl)-1-methyl-5-nitro-1H-benzo[d]imidazole , which has been used in the study of 5-nitrofuran derivatives as an inhibitor of nucleic acid and protein synthesis in Ehrlich ascites tumor cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H7D3BrN3O2, Molecular Weight: 335.17. US Biological Life Sciences.
2,4-Dichloro-7-[2-deoxy-β-D-erythro-pentofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine is a modified nucleoside compound where the pyrrolo[2,3-d]pyrimidine core is attached to a 2-deoxy-β-D-erythro-pentofuranosyl sugar moiety. The compound contains two chlorine atoms at the 2 and 4 positions of the pyrimidine ring, enhancing its chemical properties, such as its interaction with enzymes or other molecular targets. This modification of the nucleoside may alter its biological activity, potentially improving its stability, cellular uptake, or selectivity for specific biochemical processes. It could be useful in nucleic acid-based drug design, particularly for applications in gene therapy, antiviral therapies, or other therapeutic strategies targeting nucleic acids. Synonyms: 2,4-Dichloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine. Grade: ≥95%. CAS No. 1053228-44-6. Molecular formula: C11H11Cl2N3O3. Mole weight: 304.13.
2,4-Difluorobenzeneacetic Acid
2,4-Difluorophenylacetic acid is used in the synthesis of nonpolar peptide nucleic acid monomers containing fluoroaromatics (F-PNA). Group: Biochemicals. Grades: Highly Purified. CAS No. 81228-09-3. Pack Sizes: 1g, 5g. Molecular Formula: C8H6F2O2, Molecular Weight: 172.13. US Biological Life Sciences.
Worldwide
2',5'-Anhydroarabinocytidine
2',5'-Anhydroarabinocytidine is a modified nucleoside where the typical 3'-5' phosphodiester linkage between the sugar units is replaced by a 2',5'-anhydro linkage, connecting the sugar's 2' and 5' carbon atoms. The base is arabinocytidine, where the sugar is an arabinose derivative. This modification creates a unique structure that could affect the stability and interaction of the nucleoside with enzymes, such as nucleases, and may make it resistant to typical DNA or RNA degradation pathways. 2',5'-Anhydroarabinocytidine could have potential applications in nucleic acid-based therapies, where enhanced stability or altered enzymatic interactions are desired, and might be used for the development of antiviral drugs or in the synthesis of modified oligonucleotides for research purposes. Synonyms: Cytarabine Impurity F; 4-Amino-1-(2,5-anhydro-β-D-arabinofuranosyl)pyrimidin-2(1H)-one; Cytarabine EP impurity F; Cytarabine impurity 10 (or 1, 4, 17); 2',5'-Anhydro-1-(beta-D-arabinofuranosyl)cytosine; 4-Amino-1-(2,5-anhydro-β-D-arabinofuranosyl)-2(1H)-pyrimidinone; (2',5'-Anhydroarabinosyl)cytosine; NSC 340843; 4-Amino-1-((1R,3R,4S,7R)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidin-2(1H)-one. Grade: ≥95%. CAS No. 32830-01-6. Molecular formula: C9H11N3O4. Mole weight: 225.20.
2,6-Diamino-4-hydroxy-5-nitrosopyrimidine-13C2,15N is an intermediate in the synthesis of labelled Guanine (G836000). Guanine is on one of the five nucleobases incorporated into biological nucleic acids. Guanine, along with adenine and cytosine, is present in both DNA and RNA, whereas thymine is usually seen only in DNA, and uracil only in RNA. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C213C2H5N415NO2. US Biological Life Sciences.
2,6-Diamino-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-β-D-ribofuranosyl]purine, a remarkable antiviral agent utilized in the research of various viral ailments, such as herpes, hepatitis B, and the human immunodeficiency virus (HIV). Its extraordinary molecular configuration targets pivotal enzymes engaged in nucleic acid synthesis, effectively hindering viral replication and impeding the advancement of these afflictions. This unparalleled product plays a pivotal role in the realm of biomedical investigation and pharmaceutical advancement, bestowing hope in the relentless battle against insidious viral infections. Synonyms: 3',5'-TIPPS-2,6-diaminopurine riboside; 3',5'-(1,1,3,3-tetraisopropyl-1,3-disiloxan-1,3-yl)-9-(β-D-ribofuranosyl)purin-2,6-diamine; 2,6-diamino-9-(3,5-O-tetraisopropyldisiloxane-(1,3-diyl)-β-D-ribofuranosyl) purine; 3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-aminoadenosine; 9-[3,5-O-(tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranosyl]-2,6-diaminopurine. CAS No. 87791-88-6. Molecular formula: C22H40N6O5Si2. Mole weight: 524.77.
2,6-Diamino-9-(3'-amino-2',3'-dideoxy-b-D-ribofuranosyl)purine is a purine nucleoside analog that has antiviral properties due to its ability to inhibit viral nucleic acid synthesis. It is particularly effective against herpes simplex virus and varicella-zoster virus, and has also shown potential in the treatment of HIV. Its mechanism of action involves incorporation into the replicating viral DNA, leading to chain termination and inhibition of viral replication. Synonyms: 9-(3-Amino-2,3-dideoxy-b-D-ribofuranosyl)-2,6-diaminopurine; 3'-Amino-2',3'-dideoxy-2,6-diaminopurine riboside. Molecular formula: C10H15N7O2. Mole weight: 265.28.
2,6-Diaminopurine
2,6-Diaminopurine can be used as analyte for biological and analytical studies of incorporation of unnatural nucleotides into mutant tRNA and proteins. Uses: Nucleic acid synthesis inhibitors. Synonyms: 2-Aminoadenine; NSC 743; 2,6-Diamino-purine; 9H-Purine-2,6-diamine; 1H-Purine-2,6-diamine; 2,6-diamino-9H-purine. Grade: 98 %. CAS No. 1904-98-9. Molecular formula: C5H6N6. Mole weight: 150.14.
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine exhibits immense significance in the intricate process of nucleic acid synthesis. The assimilation of this entity augments the stability of pharmaceutical preparations and exerts a momentous impact on their metabolism, thereby endowing it with immense worth in the research of therapeutic interventions targeting multifarious maladies. Synonyms: 2'-Amino-2'-deoxy-5'-O-DMT-uridine; 2'-Amino-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine; 1-[(2R,3R,4S,5R)-3-amino-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione; 2'-amino-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxyuridine. Grade: ≥95%. CAS No. 174221-86-4. Molecular formula: C30H31N3O7. Mole weight: 545.58.
2'-Amino-2'-deoxyinosine
2'-Amino-2'-deoxyinosine is a valuable reagent widely used in the biomedicine industry, employed in the development of nucleic acid-based therapies and drugs, such as antisense oligonucleotides, aptamers, and gene therapy. Additionally, it finds applications in the study of various diseases, including cancer, viral infections, and genetic disorders, due to its ability to modify nucleic acid structures. Synonyms: 9-(2'-Amino-2'-deoxy-β-D-ribofuranosyl)-hypoxanthine. Grade: 98%. CAS No. 75763-51-8. Molecular formula: C10H13N5O4. Mole weight: 267.24.
2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-adenosine 3'-CE phosphoramidite stands as an indispensable entity in spurring nucleic acid synthesis. As an agent that cultivates the establishment of phosphodiester bonds in solid-phase synthesis of DNA and RNA fragments, it provides fundamental advancements to the probing and treatment of genetic maladies and cancerous conditions. When utilized to its fullest capacity, 2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-adenosine 3'-CE phosphoramidite galvanizes the synthesis of oligonucleotides and probes, profoundly accelerating treatment and diagnosis of ailments. Synonyms: 5'-(4,4'-Dimethoxytrityl)-N2,N6-bis(diisobutylaminomethylidene)-2,6-diamino-2'-deoxypurine riboside 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-D-adenosine 3'-CE phosphoramidite; 2-Amino-dA-CE phosphoramidite. Molecular formula: C58H83N10O6P. Mole weight: 1047.32.
2-Amino-6-chloro-9-(2-C-methyl-β-D-ribofuranosyl)-9H-purine possesses unique chemical properties that are invaluable in studying nucleic acid metabolism and viral pathogenesis. Additionally, this important pharmaceutical intermediate stands out as a potent inhibitor of viral DNA and RNA replication and hits the mark in blocking the synthesis of cancer cells. Its multifaceted applications extend to the treatment of viral infections, including hepatitis B and C, and oncology. Synonyms: 6-Chloro-9-(2-C-methyl-beta-D-ribofuranosyl)-9H-purin-2-amine; 2-Amino-6-chloro-9-(2-C-methyl-β-D-ribofuranosyl)purine; (2R,3R,4R,5R)-2-(2-amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol; (2R,3R,4R,5R)-2-(2-Amino-6-chloro-purin-9-yl)-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-3,4-diol. Grade: ≥95%. CAS No. 640725-74-2. Molecular formula: C11H14ClN5O4. Mole weight: 315.71.
2-Amino-6-Cl-purine-2'-deoxyriboside-Triphosphate
2-Amino-6-Cl-purine-2'-deoxyriboside-Triphosphate is a crucial reagent in the development of nucleic acid-based therapies. It is commonly used in PCR amplification assays for its high specificity, and is also used in the synthesis of modified antisense oligonucleotides targeted towards treating diseases such as cancer and viral infections. Synonyms: 2-Amino-6-Cl-purine-drTP; 2-Amino-6-Chloropurine-2'-dTP. Grade: ≥90% by AX-HPLC. Molecular formula: C10H15N5O12P3Cl. Mole weight: 525.60.
2-Amino-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine, renowned as a robust antiviral constituent, plays a pivotal role in the biomedical sector, specifically in combating DNA and RNA viral ailments. Diverse viral pathogens such as herpes simplex virus, influenza A/B, and human immunodeficiency virus (HIV) succumb to its potent antiviral properties. Its mechanism of action revolves around impeding viral nucleic acid synthesis, thereby impeding viral replication. Molecular formula: C16H19N5O7. Mole weight: 393.35.
2-Amino-benzoyl-9-(5'-O-DMT-b-D-ribofuranosyl)purine is used in biomedical research as a fluorescent probe for studying nucleic acid structure and function. It has also been used in studies on the thermodynamics and kinetics of DNA hybridization and in the development of new therapeutics for cancer and viral diseases such as HIV. Molecular formula: C38H35N5O7. Mole weight: 673.71.
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