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| Product | Description | |
|---|---|---|
| Phenanthridine | Phenanthridine appears as crystalline needles. Mutagenic. Group: Electroluminescence materials organic light-emitting diode (oled) materials other materials. Alternative Names: Benzo[c]quinoline. CAS No. 229-87-8. Product ID: phenanthridine. Molecular formula: 179.22. Mole weight: C13H9N. c1ccc2c(c1)cnc3ccccc23. 1S/C13H9N/c1-2-6-11-10 (5-1)9-14-13-8-4-3-7-12 (11)13/h1-9H, RDOWQLZANAYVLL-UHFFFAOYSA-N. RDOWQLZANAYVLL-UHFFFAOYSA-N. 98+%. |  |
| 3,8-Dinitro-6-phenyl-phenanthridine (. ) | 3,8-Dinitro-6-phenyl-phenanthridine (). Group: Biochemicals. Alternative Names: Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. |  Worldwide |
| 6-Aminophenanthridine | 6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor agonist guanabenz. Synonyms: 6-phenanthridinamine; phenanthridin-6-amine. Grade: ≥ 95 %. CAS No. 832-68-8. Molecular formula: C13H10N2. Mole weight: 194.23. |  |
| 6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine | 6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine is one of Pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: 9-cyclopropyl-15-fluoro-8-azatetracyclo; Pitavastatin Impurity 3 (PP-3). Grade: 98%. CAS No. 1187966-94-4. Molecular formula: C20H16FN. Mole weight: 289.35. | |
| 6-Cyclopropyl-10-fluorobenzo[k]phenanthridine | 6-Cyclopropyl-10-fluorobenzo[k]phenanthridine is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin Impurity 4 (PP-4). Grade: 98%. CAS No. 1187966-95-5. Molecular formula: C20H14FN. Mole weight: 287.33. | |
| Benzo(l m N)phenanthridine | Benzo(l m N)phenanthridine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: benzo(l m n)phenanthridine;4-Azapyrene;Thebenidine;Brn 0138610;Ccris 1604;Dibenzo(C,D,E)quinoline;Einecs 205-894-8;Pyrenidine. Product Category: Heterocyclic Organic Compound. CAS No. 194-03-6. Molecular formula: C15H9N. Product ID: ACM194036. Alfa Chemistry ISO 9001:2015 Certified. |  |
| N,N'-(6-Phenyl-phenanthridine-3,8-diyl)-bis-ethyl carbamate | N,N'-(6-Phenyl-phenanthridine-3,8-diyl)-bis-ethyl carbamate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,8-DI-(ETHOXYCARBONYLAMINO)-6-PHENYLPHENANTHRIDINE;diethyl (6-phenyl-3,8-phenanthrylene)dicarbamate;N,N'-(6-Phenyl-phenanthridine-3,8-diyl)-bis-ethylCarbamate;3,8-Bis(ethoxycarbonylamino)-6-phenylphenanthridine;N,N'-(6-Phenyl-3,8-phenanthridinediyl)bis(. Product Category: Heterocyclic Organic Compound. Appearance: Pale Yellow Solid. CAS No. 62895-39-0. Molecular formula: C25H23N3O4. Mole weight: 429.47. Product ID: ACM62895390. Alfa Chemistry ISO 9001:2015 Certified. | |
| N,N'-(6-Phenylphenanthridine-3,8-diyl)-bis-ethyl carbamate | N,N'-(6-Phenylphenanthridine-3,8-diyl)-bis-ethyl carbamate. Group: Biochemicals. Alternative Names: 3,8-Bis(carbethoxyamino)-6-phenylphenanthridine; N,N'-(6-Phenyl-3,8-phenanthridinediyl)bis-carbamic acid C,C'-diethyl ester. Grades: Highly Purified. CAS No. 62895-39-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C25H23N3O4. US Biological Life Sciences. | Worldwide |
| N,N'-(6-Phenyl-phenanthridine-3,8-diyl)-bis-ethyl Carbamate. | N,N'-(6-Phenyl-phenanthridine-3,8-diyl)-bis-ethyl Carbamate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 2-Bromo-1-chloro-4-methyl-benzene | 2-Bromo-1-chloro-4-methyl-benzene is a useful synthetic intermediate. It can be used to synthesize N-heterocycle-fused phenanthridines via palladium-catalyzed tandem N-H/C-H arylation of aryl-N-heteroarenes with dihaloarenes. It can also be used to synthesize substituted fluorenes. Group: Biochemicals. Grades: Highly Purified. CAS No. 57310-39-1. Pack Sizes: 1g, 5g. Molecular Formula: C7H6BrCl. US Biological Life Sciences. | Worldwide |
| 3-Bromo-4-chloroanisole | 3-Bromo-4-chloroanisole is a useful synthetic intermediate. It can be used in the synthesis of N-heterocycle-fused phenanthridines as blue-emitting luminophores. It can also be used to prepare indoles (Indole, I577320) by a Pd-Catalyzed Cascade process. Group: Biochemicals. Grades: Highly Purified. CAS No. 2732-80-1. Pack Sizes: 1g, 5g. Molecular Formula: C7H6BrClO. US Biological Life Sciences. | Worldwide |
| (3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt | (3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (βR,δS)-6-Cyclopropyl-10-fluoro-7,8-dihydro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid Sodium Salt. Molecular formula: C25H23FNNaO4. Mole weight: 443.44. | |
| 6-Methoxydihydrosanguinarine | 6-Methoxydihydrosanguinarine is an alkaloid isolated from Hylomecon hylomeconoides. 6-Methoxydihydrosanguinarine exhibits anti-inflammatory activity via inhibition of NO and IL-6 expression, and antibacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA) strains. 6-Methoxydihydrosanguinarine also induces apoptotic cell death in HT29 colon carcinoma cells dose-dependently. Synonyms: [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine, 13,14-dihydro-14-methoxy-13-methyl-, (-)-; (-)-13,14-Dihydro-14-methoxy-13-methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine; (-)-Sanguinarine pseudomethanolate; (-)-6-Methoxydihydrosanguinarine. Grade: ≥95%. CAS No. 72401-54-8. Molecular formula: C21H17NO5. Mole weight: 363.36. | |
| 6-Phenylphenathridine-3,8-diamine | 6-Phenylphenathridine-3,8-diamine. Group: Biochemicals. Alternative Names: 3,8-Diamino-6-phenylphenanthridine6-phenyl-3,8-phenanthridinediamine. Grades: Highly Purified. CAS No. 52009-64-0. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C19H15N3. US Biological Life Sciences. | Worldwide |
| Chelerythrine | Chelerythrine is a benzophenanthridine alkaloid extracted from the plant Greater celandine (Chelidonium majus). It is a potent, selective, and cell-permeable protein kinase C inhibitor. It is also the major active natural product found in the plant Zanthoxylum clava-herculis, exhibiting anti-bacterial activity against Staphylococcus aureus. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 μM and displaces Bax from BclXL. Chelerythrine triggers apoptosis and autophagy. Uses: Antibacterial agent. Synonyms: Toddalin; cheleritrine; broussonpapyrine; Toddaline; [1,3]Benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-; NSC646662; 1,2-Dimethoxy-N-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium chloride. Grade: 98%. CAS No. 34316-15-9. Molecular formula: C21H18NO4+. Mole weight: 348.37. | |
| Corynoline | Corynoline, which is found in the tubers of Corydalis ambigua, is an acetylcholinesterase inhibitor. Uses: Sedative/anti-leptospira. Synonyms: Corynoline; [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-, dimethyl-, (5bR,6S,12bR)-; (5bR)-5bα,13-Dimethyl-5bα,6,7,12bα,13,14-hexahydro[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine-6β-ol; 13-Methylchelidonan-11β-ol. Grade: >98%. CAS No. 18797-79-0. Molecular formula: C21H21NO5. Mole weight: 367.4. | |
| Dihydrexidine | Dihydrexidine. Group: Biochemicals. Alternative Names: (6aR,12bS)-rel-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol; trans-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol. Grades: Highly Purified. CAS No. 123039-93-0. Pack Sizes: 1mg. Molecular Formula: C17H17NO2, Molecular Weight: 267.32. US Biological Life Sciences. | Worldwide |
| Dihydrexidine | Dihydrexidine is a highly potent, selective and full-acting D1-like dopamine receptor (D1/D5) agonist with an IC50 of 10 nM against D1 receptor. It shows potent anti-Parkinson's activity and stimulates YAP phosphorylation. Synonyms: DAR-0100; Benzo(a)phenanthridine-10,11-diol, 5,6,6a,7,8,12b-hexahydro-, (6aR,12bS)-rel-; (6aR,12bS)-rel-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium. Grade: ≥95%. CAS No. 123039-93-0. Molecular formula: C17H17NO2. Mole weight: 267.32. | |
| Dihydrexidine hydrochloride | Dihydrexidine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Dihydrexidine hydrochloride;(+/-)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride. Product Category: Heterocyclic Organic Compound. CAS No. 123039-93-0. Molecular formula: C17H17NO2.HCl. Mole weight: 303.78. Purity: >99 %. Product ID: ACM123039930. Alfa Chemistry ISO 9001:2015 Certified. | |
| Dihydrexidine hydrochloride | The hydrochloride salt form of Dihydrexidine, which has been found to be an effective full efficacy dopamine D1 agonist and show antiparkinsonism effects in vivo. Synonyms: (±)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride. Grade: ≥98% by HPLC. CAS No. 158704-02-0. Molecular formula: C17H17NO2.HCl. Mole weight: 303.79. | |
| Dihydrochelerythrine | Dihydrochelerythrine is a natural compound isolated from Corydalis yanhusuo; has antifungal activity.IC50 value:Target:in vitro: Dihydrochelerythrine showed the highest antifungal activity against B. cinerea Pers, with 98.32% mycelial growth inhibition at 50 μg/mL. Dihydrochelerythrine inhibited spore germination in vitro in a concentration-dependent manner. Dihydrochelerythrine appeared to be less cytotoxic since the viability of cells exposed to 20 microM dihydrochelerythrine for 24h was reduced only to 53%. A dose-dependent induction of apoptosis and necrosis by chelerythrine and dihydrochelerythrine was confirmed by annexin V/propidium iodide dual staining flow cytometry. Dihydrochelerythrine (4) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 12,13-Dihydro-1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridine. Product Category: Inhibitors. Appearance: Solid. CAS No. 6880-91-7. Molecular formula: C21H19NO4. Mole weight: 349.4. Purity: 95%+. Canonical SMILES: CN1C(C2=CC(OCO3)=C3C=C2C=C4)=C4C5=CC=C(OC)C(OC)=C5C1. Product ID: ACM6880917. Alfa Chemistry ISO 9001:2015 Certified. | |
| Dihydroethidium | Dihydroethidium. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,7-Diamino-10-ethyl-9-phenyl-9,10-dihydrophenthridine,3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenthridine. Product Category: Other Fluorophores. Appearance: Pink solid. CAS No. 104821-25-2. Molecular formula: C21H21N3. Mole weight: 315.41. Purity: 95%+. IUPACName: 5-ethyl-6-phenyl-6H-phenanthridine-3,8-diamine. Canonical SMILES: CCN1C(C2=C(C=CC(=C2)N)C3=C1C=C(C=C3)N)C4=CC=CC=C4. Product ID: ACM104821252-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Dihydro sanguinarine | Dihydro sanguinarine. Group: Biochemicals. Alternative Names: 13,14-Dihydro-13-methyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine; 13,14-Dihydrosanguinarine; Hydrosanguinarine. Grades: Highly Purified. CAS No. 3606-45-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H15NO4. US Biological Life Sciences. | Worldwide |
| Dynemicin A | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. Dynemicin A has a strong killing effect on a variety of tumor cells at Pg/mL level. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1S,4R,4aR,14S,14aS)-1,4,4a,7,12,13,14,14a-Octahydro-6,8,11-trihydroxy-3-methoxy-1-methyl-7,12-dioxo-4a,14a-epoxy-4,14-(3-hexene-1,5-diyne-1,6-diyl)naphtho[2,3-c]phenanthridine-2-carboxylicacid; Dynemicin; BU 3420T. Grade: 95%. CAS No. 124412-57-3. Molecular formula: C30H19NO9. Mole weight: 537.47. | |
| Dynemicin M | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a-pentahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione. Grade: ≥98%. CAS No. 127003-54-7. Molecular formula: C29H23NO9. Mole weight: 529.49. | |
| Dynemicin O | It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a,17-hexahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione; (8R-(8alpha,9beta,14beta,17S*,18R*))-8,9,14,15-Tetrahydro-1,4,6,8,10,17-hexahydroxy-20-methoxy-18-methyl-9,8,14-(1)butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione. CAS No. 138370-12-4. Molecular formula: C29H23NO10. Mole weight: 545.49. | |
| Dynemicin P | It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-3β,4a,6,8,11,14a-hexahydroxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione; 9,8,14-(1)Butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione,8,9,14,15-tetrahydro-1,4,6,8,17,20-hexahydroxy-18-methyl-, (8R-(8alpha,9beta,14beta,17S*,18R*))-. CAS No. 138370-13-5. Molecular formula: C28H21NO9. Mole weight: 515.47. | |
| HLY78 | HLY78 is an activator of the Wnt/β-catenin pathway. It targets the DIX domain of Axin and potentiates the Axin-LRP6 association, thus promoting LRP6 phosphorylation and Wnt signaling transduction. In zebrafish embryos, HLY78 was shown to increase the expression of the conserved hematopoietic stem cell (HSC) markers, runx1 and cmyb. Synonyms: 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine. Grade: ≥98%. CAS No. 854847-61-3. Molecular formula: C17H17NO2. Mole weight: 267.3. | |
| Jadomycin B | Jadomycin B is an angucyclic natural product produced by Streptomyces venezuelae ISP5230. It exhibits antimicrobial, antitumor activity and inhibits aurora-B kinase and DNA cleaving. It was also shown to be effective against a variety of staphylococci. Synonyms: 1-(sec-butyl)-12-((4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-7-hydroxy-5-methyl-8H-benzo[b]oxazolo[3,2-f]phenanthridine-2,8,13(1H,3aH)-trione; 8H-Benzo(b)oxazolo(3,2-f)phenanthridine-2,8,13(1H,3aH)-trione, 12-((2,6-dideoxyhexopyranosyl)oxy)-7-hydroxy-5-methyl-1-(1-methylpropyl)-. Grade: ≥98% by HPLC. CAS No. 149633-99-8. Molecular formula: C30H31NO9. Mole weight: 549.6. | |
| Lycorine hydrochloride | Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily , surprise lilies, and daffodils. It may be highly poisonous, or even lethal, when ingested in certain quantities. Symptoms of lycorine toxicity are vomiting, diarrhea, and convulsions. Uses: Adcs cytotoxin. Synonyms: Lycorine hydrochloride; 2188-68-3; Lycorine chloride; Lycorine HCl; Licorin hydrochloride; Lycorine (hydrochloride); 58F70VH0HS; 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-, hydrochloride (1:1), (1S,2S,12bS,12cS)-; (1S,2S,3a1S,12bS)-2,3a1,4,5,7,12b-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol hydrochloride; (1S,17S,18S,19S)-. Grade: 98 %. (NMR). CAS No. 2188-68-3. Molecular formula: C13H19NO4S. Mole weight: 299.45. | |
| Lycorine Hydrochloride | Lycorine Hydrochloride. Group: Biochemicals. Alternative Names: Licorin Hydrochloride; 3,3a-Didehydrolycoran-1α,2 β-diol Hydrochloride; (1α,2 β)-3,12-Didehydro-9,10-[methylenebis(oxy)]-galanthan-1,2-diol; 2,4,5,7,12b,12c-Hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol Hydrochloride; (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-Hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol. Grades: Highly Purified. CAS No. 2188-68-3. Pack Sizes: 50mg. Molecular Formula: C16H18ClNO4, Molecular Weight: 323.77. US Biological Life Sciences. | Worldwide |
| Norchelerythrine | Norchelerythrine is an alkaloid isolated from Chelidonium majus that exhibits antifeeding activity. Synonyms: 1,2-dimethoxy-[1,3]benzodioxolo[5,6-c]phenanthridine. Grade: 98.0%. CAS No. 6900-99-8. Molecular formula: C20H15NO4. Mole weight: 333.343. | |
| Norsanguinarine | Norsanguinarine is an isoquinoline alkaloid isolated from Chelidonium majus. Norsanguinarine exhibits antimicrobial, anti-inflammatory, and anti-oxidant activities. Synonyms: Sanguinarine, 13-demethyl-; (1,3)Benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridine; 1,3-Dioxolo(I)(1,3)dioxolo(4,5)benzo(1,2-c)phenanthridine; 1,3-Dioxolo[i][1,3]dioxolo[4,5]benzo[1,2-c]phenanthridine. Grade: 98.0%. CAS No. 522-30-5. Molecular formula: C19H11NO4. Mole weight: 317.3. | |
| Propidium Iodide ≥95% (HPLC) | Propidium Iodide is a phenanthridine compound, a class of compounds with reported activity against several species of trypanosomes. Propidium iodide may be used in flow cytometry to evaluate cell viability when used with other dyes that stain viable cells or cells that are early in the apoptosis process. Propidium iodide (PI) is a fluorescent dye [FW 668.41] that binds specifically to DNA. This property has led to its common use in evaluation of cell cycle, aneuploidy and apoptosis by flow cytometry. When excited by a laser light at 488nm, PI emits a signal that can be monitored by the red wavelength detector typically reserved for phycoerythrin (usually FL2). Propidium iodide is excluded from viable cells, thus analysis of DNA content in cells requires membrane permeabilization. In evaluation of apoptosis, PI is used to distinguish necrotic cells or cells in late stages of apoptosis, which have permeabilized membranes and thus bind PI, from viable cells or cells in early apoptosis whe Group: Biochemicals. Alternative Names: 3, 8-Diamino-5-[3- (diethylmethylammonio) propyl]-6-phenylphenanthridinium Iodide; 3,8-Diamino-5-(3-diethylaminopropyl)-6-phenylphenanthridinium Iodide Methiodide; [3- (3, 8-Diamino-6-phenyl-5-phenanthridinio) propyl]. Grades: Reagent Grade. CAS No. 25535-16-4. Pack Sizes: 25mg, 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| 2-(2-(4-Phenanthridin-6-yl)piperazin-1-yl)ethoxy)ethanol | A useful synthetic intermediate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C21H25N3O2, Molecular Weight: 351.44. US Biological Life Sciences. | Worldwide |
| 2-(2-(4-Phenanthridin-6-yl)piperazin-1-yl)ethoxy)ethanol-D8 | 2-(2-(4-Phenanthridin-6-yl)piperazin-1-yl)ethoxy)ethanol-D8 is a labelled analogue of 2-(2-(4-Phenanthridin-6-yl)piperazin-1-yl)ethoxy)ethanol (P312650). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C21H17D8N3O2, Molecular Weight: 359.49. US Biological Life Sciences. | Worldwide |
| 2, 3, 7, 8-Tetrahydroxy-5-methyl-benzo [c]phenanthridinium Chloride | 2, 3, 7, 8-Tetrahydroxy-5-methyl-benzo [c]phenanthridinium Chloride is an intermediate in the synthesis of Sanguinarium-13CD3 Chloride (S112502). Sanguinarium-13CD3 Chloride is the labeled analogue of Sanguinarium Chloride (S112500). Sanguinarium Chloride is a natural product with antimicrobial, anti-inflammatory, and anti-oxidant properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 1099740-10-9. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C18H14NO4+ + Cl-, Molecular Weight: 308.313544999999. US Biological Life Sciences. | Worldwide |
| 2-Bromobenzamide | 2-Bromobenzamide has been used in microwave assisted one-pot synthesis of substituted 3- (phenylmethylene) isoindolin-1-ones, palladium-catalyzed synthesis of phenanthridinones and synthesis of new water-soluble iminophosphorane ligand. Group: Biochemicals. Grades: Highly Purified. CAS No. 4001-73-4. Pack Sizes: 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| 2-Bromophenanthridone | 2-Bromophenanthridone is a 2-bromo substituted derivative of phenathridinone that exhibits aryl hydrocarbon (Ah) receptor antagonist activity. It is also used in the preparation of potential HIV-1 integrase inhibitors. Group: Biochemicals. Alternative Names: 2-Bromo-6(5H)-phenanthridinone; NSC 112910; SG 00589. Grades: Highly Purified. CAS No. 27353-48-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 3, 8-Bis (ethoxycarbonylamino)-5- (3-bromopropyl)-6-phenyl-phenanthridinium bromide | 3, 8-Bis (ethoxycarbonylamino)-5- (3-bromopropyl)-6-phenyl-phenanthridinium bromide. Group: Biochemicals. Alternative Names: 5- (3-Bromopropyl)-3, 8-bis[ (ethoxycarbonyl)amino]-6-phenyl-phenanthridinium bromide. Grades: Highly Purified. CAS No. 62113-49-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C28H29Br2N3O4. US Biological Life Sciences. | Worldwide |
| 3,8-Bis-ethoxycarbonylamino-5-(3-bromo-propyl)-6-phenyl-phenanthridinium bromide | 3,8-Bis-ethoxycarbonylamino-5-(3-bromo-propyl)-6-phenyl-phenanthridinium bromide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(3-Bromopropyl)-3,8-bis[(ethoxycarbonyl)amino]-6-phenyl-phenanthridinium Bromide. Product Category: Heterocyclic Organic Compound. Appearance: Yellow Solid. CAS No. 62113-49-9. Molecular formula: C28H29Br2N3O4. Mole weight: 631.3556. Purity: 0.96. IUPACName: ethyl N-[5-(3-bromopropyl)-3-(ethoxycarbonylamino)-6-phenylphenanthridin-5-ium-8-yl]carbamate;bromide. Canonical SMILES: CCOC(=O)NC1=CC2=C([N+](=C3C=C(C=CC3=C2C=C1)NC(=O)OCC)CCCBr)C4=CC=CC=C4.[Br-]. Density: g/cm³. ECNumber: 263-412-1. Product ID: ACM62113499. Alfa Chemistry ISO 9001:2015 Certified. | |
| 3,8-Bis-ethoxycarbonylamino-5-(3-bromo-propyl)-6-phenyl. -phenanthridinium Bromide. | 3,8-Bis-ethoxycarbonylamino-5-(3-bromo-propyl)-6-phenyl-phenanthridinium Bromide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 3,8-Bis-ethoxycarbonylamino-5-(3-diethylamino-propyl)-6-phenyl-. phenanthridinium Chloride. | 3,8-Bis-ethoxycarbonylamino-5-(3-diethylamino-propyl)-6-phenyl-phenanthridinium Chloride. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 6(5H)-phenanthridinone | 6(5H)-phenanthridinone. CAS No: 1015-89-0 |  Sarchem Laboratories New Jersey NJ |
| 6(5H)-Phenanthridinone | 6(5H)-Phenanthridinone is a potent PARP-1 inhibitor and immunomodulator. 6(5H)-Phenanthridinone inhibits cell proliferation and can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1015-89-0. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-34386. |  |
| 6-Phenanthridone | 6-Phenanthridone is a poly(ADP-ribose) polymerase (PARP) inhibitor with immunosuppressive effects. 6-Phenanthridone has been shown to inhibit concanavalin A-induced lymphocyte proliferation. Group: Biochemicals. Alternative Names: 5H-Phenanthridin-6-one; 6-Phenanthridinol; 6-Phenanthridinone; 6-Phenanthridone; NSC 11021; NSC 40943; NSC 61083; PJ 97A; 6(5H)-Phenanthridinone; WD 99-004344. Grades: Highly Purified. CAS No. 1015-89-0. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| a-Allocryptopine | a-Allocryptopine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: HOMOCHELIDONINE;HOMOCHELIDONINE, A-;A-ALLOCRYPTOPINE;A-HOMOCHELIDONINE;ALPHA-HOMOCHELIDONINE;[4bR-(4balpha,5beta,11balpha)]-4b,5,6,11b,12,13-hexahydro-1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-5-ol;HOMOCHELIDONINE, a-(P);(4bR)-4b,5,6,1. Product Category: Heterocyclic Organic Compound. CAS No. 476-33-5. Molecular formula: C21H23NO5. Mole weight: 369.41. Purity: 0.96. IUPACName: (4bR,5S,11bS)-1,2-dimethoxy-12-methyl-5,6,11b,13-tetrahydro-4bH-[1,3]benzodioxolo[5,6-c]phenanthridin-5-ol. Canonical SMILES: CN1CC2=C(C=CC(=C2OC)OC)C3C1C4=CC5=C(C=C4CC3O)OCO5. Density: 1.294g/cm³. ECNumber: 207-505-7. Product ID: ACM476335. Alfa Chemistry ISO 9001:2015 Certified. | |
| Chelerythrine | Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 μM. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 μM and displaces Bax from BclXL. Chelerythrine triggers apoptosis and autophagy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Broussonpapyrine; Cheleritrine; Chelerythrin; Chelerythrine chloride; Chelerythrin-Kation; Chelerythrine; Chelerythrin chlorid. Product Category: Inhibitors. CAS No. 34316-15-9. Molecular formula: C21H18ClNO4. Mole weight: 348.83. Purity: 95%-99%. IUPACName: 1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium. Canonical SMILES: C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5. ECNumber: 251-930-0. Product ID: ACM34316159. Alfa Chemistry ISO 9001:2015 Certified. | |
| Chelerythrine chloride | Cell permeable potent inhibitor of protein kinase C. Does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase or calcium/calmodulin-dependent protein kinase. Antiplatelet, anti-inflammatory, antibacterial and antitumor compound. Apoptosis inducer in cancer cells in vitro and in vivo. Activates MAPK and JUNK signaling pathways. Affects translocation of PKC from cytosol to plasma membrane. Neurite outgrowth stimulator. Inhibits binding of BclXL to Bak (IC50 =1.5uM) or Bad proteins and stimulates apoptosis in several cancer cell lines. Blocks human P2X7 receptor. Induces cell cycle arrest in G1 phase. Specific cyclooxygenase-2 inhibitor. Group: Biochemicals. Alternative Names: NSC 36405, 1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride. Grades: Highly Purified. CAS No. 3895-92-9. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C21H18ClNO4. US Biological Life Sciences. | Worldwide |
| Chelerythrine chloride | Chelerythrine chloride is a potent, cell-permeable inhibitor of protein kinase C, with an IC50 of 660 nM. Chelerythrine chloride inhibits the Bcl-XL-Bak BH3 peptide binding with IC50 of 1.5 μM and displaces Bax from Bcl-XL. Chelerythrine chloride induces apoptosis and autophagy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,2-Dimethoxy-12-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-12-ium chloride. Product Category: Inhibitors. CAS No. 3895-92-9. Mole weight: 383.8. Purity: 95%+. Product ID: ACM3895929. Alfa Chemistry ISO 9001:2015 Certified. | |
| CY 208-243 | CY 208-243 is a D1DR receptor agonist and has been found to show antiparkinsonian activity in animal models. Synonyms: CY 208-243; CY-208-243; CY208243; (-)-(6aR,12bR)-4,6,6a,7,8,12b-Hexahydro-7-methylindolo[4,3-a]phenanthridin. Grade: ≥95% by HPLC. CAS No. 100999-26-6. Molecular formula: C19H18N2. Mole weight: 274.36. | |
| Decarine | Decarine isolated from the roots of Zanthoxylum nitidum. It has low cytotoxicity towards human macrophages. Uses: Antibacterial activity. Synonyms: 1-methoxy-[1,3]benzodioxolo[5,6-c]phenanthridin-2-ol. Grade: 97.5%. CAS No. 54354-62-0. Molecular formula: C19H13NO4. Mole weight: 319.3. | |
| Dimidium Bromide | Dimidium bromide is an inhibitor of L-cell growth. Dimidium Bromide is used as an intercalating probe for nucleic acids. Group: Biochemicals. Alternative Names: 3,8-Diamino-5-methyl-6-phenylphenanthridinium Bromide; Dimidium bromide; Phenanthridinium Compound 1553; Phenanthridium 1553; Trypadine. Grades: Highly Purified. CAS No. 518-67-2. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| Ethidium bromide-N N-bisacrylamide | Ethidium bromide-N N-bisacrylamide. Group: other materials. Alternative Names: ETHIDIUM BROMIDE-N N-BISACRYLAMIDE; 3,8-bisacrylamido-5-ethyl-6-phenylphenanthridinium bromide; 3,8-Bisacrylamido-5-ethyl-6-phenylphenanthridiniumbromide,3,8-Bisacryloylethidiumbromide. CAS No. 480438-67-3. Product ID: N-[5-ethyl-6-phenyl-3-(prop-2-enoylamino)phenanthridin-5-ium-8-yl]prop-2-enamide; bromide. Molecular formula: 502.4g/mol. Mole weight: C27H24BrN3O2. CC[N+]1=C2C=C (C=CC2=C3C=CC (=CC3=C1C4=CC=CC=C4)NC (=O)C=C)NC (=O)C=C. [Br-]. InChI=1S/C27H23N3O2. BrH/c1-4-25 (31)28-19-12-14-21-22-15-13-20 (29-26 (32)5-2)17-24 (22)30 (6-3)27 (23 (21)16-19)18-10-8-7-9-11-18; /h4-5, 7-17H, 1-2, 6H2, 3H3, (H, 28, 31); 1H. VVSGFSHAUFPBFM-UHFFFAOYSA-N. | |
| Glutaminase C-IN-1 | Glutaminase C-IN-1, with effect to suppresse breast cancer cell growth and invasive activity in vitro, it is an allosteric, cell-permeable and reversible inhibitor of lutaminase C (IC50 = ~2.5 μM). Synonyms: GLS-IN-968; GLS IN 968; GLSIN968; Glutaminase inhibitor-968; Glutaminase inhibitor 968; GLS inhibitor 968; Glutaminase inhibitor compound 968; 5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-1,3,5,6-tetrahydrobenzo[a]phenanthridin-4-one5-(3-bromo-4-(dimethylamino)phenyl)-2,2-dimethyl-2,3,5,6-tetrahydrobenzo(a)phenanthridin-4(1H)-one. CAS No. 311795-38-7. Molecular formula: C27H27BrN2O. Mole weight: 475.42. | |
| Glutaminase Inhibitor, Compound 968 (5- (3-Bromo-4- (dimethylamino) phenyl) -2, 2-dimethyl-2, 3, 5, 6-tetrahydrobenzo [a]phenanthridin-4 (1H) -one, GAC Inhibitor, GLS1 Inhibitor I, KGA Inhibitor I, Kidney-Type Glutaminase Inhibitor I) | A cell-permeable benzophenanthridinone compound that acts as an allosteric and reversible inhibitor of mitochondrial glutaminase activity and represses the growth and invasive activity in glutaminase upregulated fibroblasts and in tumor cells (IC50 <10uM in NIH3T3 cells stably expressing Dbl, Cdc42-F28L, Rac-F28L or RhoC-F30L mutants and in SKBR3 and MDA-MB231 cancer cells). Shown to effectively shrink tumor size in P-493 B xenografted mouse model (200 µg per inj. i.p., 12 days). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Macleaya cordata extract | Macleaya cordata extract. Uses: Designed for use in research and industrial production. Additional or Alternative Names: chelerythrine chloride-sanguinarine chloride mixt.;Macleaya cordata extract;13-Methyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium chloride mixt. with 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride;13-Methyl-[1,3]. Product Category: Heterocyclic Organic Compound. CAS No. 112025-60-2. Molecular formula: C20H14NO4.Cl;C21H18NO4.Cl. Mole weight: N/A. Product ID: ACM112025602. Alfa Chemistry ISO 9001:2015 Certified. | |
| Nitidine chloride | Nitidine chloride, that comes from the roots of Zanthoxylum nitidum (Roxb.) DC, could be developed as a potential anticancer agent to renal cancer and worthy of further studies. Nitidine chloride inhibited the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and identified efficacy in vivo in a mouse model of HCC. Uses: Anticancer/anti-metastasis. Synonyms: 2,3-Dimethoxy-12-methyl-(1,3)-benzodioxolo(5,6-c)phenanthridinium chloride; [1,3]Dioxolo[4,5]benzo[1,2-c]phenanthridinium, 2,3-; dimethoxy-12-methyl-,chloride; Angolinine; 2,3-DiMethoxy-12-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-12-ium chloride. Grade: >98%. CAS No. 13063-04-2. Molecular formula: C21H18ClNO4. Mole weight: 383.83. | |
| PJ 34 Hydrochloride | A poly adenosine diphosphate-ribose polymerase inhibitor, attenuates chromate-induced nephrotoxicity. Group: Biochemicals. Alternative Names: N- (5, 6-Dihydro-6-oxo-2-phenanthridinyl) -2- (dimethylamino) acetamide. Grades: Highly Purified. CAS No. 344458-15-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PJ-34 Hydrochloride | A potent, water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC50 = 20nM). Inhibits peroxynitrite-induced cell necrosis and displays significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Suppresses cell growth in liver cancer cells. Group: Biochemicals. Alternative Names: N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| PJ-34 (N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide. HCl) | Potent, water soluble poly(ADP-ribose) polymerase (PARP) inhibitor. Inhibits peroxynitrite-induced cell necrosis. Shows significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Shows protective effects in models of stroke. Suppresses cell growth in liver cancer cells. Group: Biochemicals. Alternative Names: N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide. HCl. Grades: Highly Purified. CAS No. 344458-15-7. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Propidium Iodide Solution, 1mg/ml | Propidium iodide (PI) is a fluorescent dye [FW 668.41] that binds specifically to DNA. This property has led to its common use in evaluation of cell cycle, aneuploidy and apoptosis by flow cytometry. When excited by a laser light at 488 nm, PI emits a signal that can be monitored by the red wavelength detector typically reserved for phycoerythrin (usually FL2). Propidium iodide is excluded from viable cells, thus analysis of DNA content in cells requires membrane permeabilization. In evaluation of apoptosis, PI is used to distinguish necrotic cells or cells in late stages of apoptosis, which have permeabilized membranes and thus bind PI, from viable cells or cells in early apoptosis where membranes are intact and PI is excluded. Group: Biochemicals. Alternative Names: 3, 8-Diamino-5-[3- (diethylmethylammonio) propyl]-6-phenylphenanthridinium Iodide; 3,8-Diamino-5-(3-diethylaminopropyl)-6-phenylphenanthridinium Iodide Methiodide; [3- (3, 8-Diamino-6-phenyl-5-phenanthridinio) propyl] diethylmethylammonium Diiodide; 3, 8-Diamino-5- (diethyl methyl aminopropyl ) -6-phenylphenanthridinium Diiodide; Propidium Diiodide. Grades: Molecular Biology Grade. CAS No. 25535-16-4. Pack Sizes: 10ml. US Biological Life Sciences. | Worldwide |
| Sanguinarium chloride | Sanguinarium chloride. Group: Biochemicals. Alternative Names: 13-Methyl[1, 3]benzodioxolo[5, 6-c]-1, 3-dioxolo[4, 5-i]phenanthridinium chloride; Sanguinarine hydrochloride. Grades: Highly Purified. CAS No. 5578-73-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C20H14ClNO4. US Biological Life Sciences. | Worldwide |
| Sanguinarium Chloride-d4 | Sanguinarium Chloride-d4. Group: Biochemicals. Alternative Names: 13-Methyl[1, 3]benzodioxolo[5, 6-c]-1, 3-dioxolo[4, 5-i]phenanthridinium Chloride-d4; Sanguinarine Hydrochloride-d4. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C20H10D4ClNO4, Molecular Weight: 371.81. US Biological Life Sciences. | Worldwide |
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