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| Product | Description | |
|---|---|---|
| Phenanthridine | Phenanthridine appears as crystalline needles. Mutagenic. Group: Electroluminescence materials organic light-emitting diode (oled) materials other materials. Alternative Names: Benzo[c]quinoline. CAS No. 229-87-8. Product ID: phenanthridine. Molecular formula: 179.22. Mole weight: C13H9N. c1ccc2c(c1)cnc3ccccc23. 1S/C13H9N/c1-2-6-11-10 (5-1)9-14-13-8-4-3-7-12 (11)13/h1-9H, RDOWQLZANAYVLL-UHFFFAOYSA-N. RDOWQLZANAYVLL-UHFFFAOYSA-N. 98+%. |  |
| 3,8-Dinitro-6-phenyl-phenanthridine (. ) | 3,8-Dinitro-6-phenyl-phenanthridine (). Group: Biochemicals. Alternative Names: Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. |  Worldwide |
| 6-Aminophenanthridine | 6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor agonist guanabenz. Synonyms: 6-phenanthridinamine; phenanthridin-6-amine. Grades: ≥ 95 %. CAS No. 832-68-8. Molecular formula: C13H10N2. Mole weight: 194.23. |  |
| 6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine | 6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine is one of Pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: 9-cyclopropyl-15-fluoro-8-azatetracyclo; Pitavastatin Impurity 3 (PP-3). Grades: 98%. CAS No. 1187966-94-4. Molecular formula: C20H16FN. Mole weight: 289.35. | |
| 6-Cyclopropyl-10-fluorobenzo[k]phenanthridine | 6-Cyclopropyl-10-fluorobenzo[k]phenanthridine is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin Impurity 4 (PP-4). Grades: 98%. CAS No. 1187966-95-5. Molecular formula: C20H14FN. Mole weight: 287.33. | |
| Benzo(l m N)phenanthridine | Benzo(l m N)phenanthridine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: benzo(l m n)phenanthridine;4-Azapyrene;Thebenidine;Brn 0138610;Ccris 1604;Dibenzo(C,D,E)quinoline;Einecs 205-894-8;Pyrenidine. Product Category: Heterocyclic Organic Compound. CAS No. 194-03-6. Molecular formula: C15H9N. Product ID: ACM194036. Alfa Chemistry ISO 9001:2015 Certified. |  |
| N,N'-(6-Phenyl-phenanthridine-3,8-diyl)-bis-ethyl carbamate | N,N'-(6-Phenyl-phenanthridine-3,8-diyl)-bis-ethyl carbamate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,8-DI-(ETHOXYCARBONYLAMINO)-6-PHENYLPHENANTHRIDINE;diethyl (6-phenyl-3,8-phenanthrylene)dicarbamate;N,N'-(6-Phenyl-phenanthridine-3,8-diyl)-bis-ethylCarbamate;3,8-Bis(ethoxycarbonylamino)-6-phenylphenanthridine;N,N'-(6-Phenyl-3,8-phenanthridinediyl)bis(. Product Category: Heterocyclic Organic Compound. Appearance: Pale Yellow Solid. CAS No. 62895-39-0. Molecular formula: C25H23N3O4. Mole weight: 429.47. Product ID: ACM62895390. Alfa Chemistry ISO 9001:2015 Certified. | |
| N,N'-(6-Phenylphenanthridine-3,8-diyl)-bis-ethyl carbamate | N,N'-(6-Phenylphenanthridine-3,8-diyl)-bis-ethyl carbamate. Group: Biochemicals. Alternative Names: 3,8-Bis(carbethoxyamino)-6-phenylphenanthridine; N,N'-(6-Phenyl-3,8-phenanthridinediyl)bis-carbamic acid C,C'-diethyl ester. Grades: Highly Purified. CAS No. 62895-39-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C25H23N3O4. US Biological Life Sciences. | Worldwide |
| N,N'-(6-Phenyl-phenanthridine-3,8-diyl)-bis-ethyl Carbamate. | N,N'-(6-Phenyl-phenanthridine-3,8-diyl)-bis-ethyl Carbamate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 2-Bromo-1-chloro-4-methyl-benzene | 2-Bromo-1-chloro-4-methyl-benzene is a useful synthetic intermediate. It can be used to synthesize N-heterocycle-fused phenanthridines via palladium-catalyzed tandem N-H/C-H arylation of aryl-N-heteroarenes with dihaloarenes. It can also be used to synthesize substituted fluorenes. Group: Biochemicals. Grades: Highly Purified. CAS No. 57310-39-1. Pack Sizes: 1g, 5g. Molecular Formula: C7H6BrCl. US Biological Life Sciences. | Worldwide |
| 3-Bromo-4-chloroanisole | 3-Bromo-4-chloroanisole is a useful synthetic intermediate. It can be used in the synthesis of N-heterocycle-fused phenanthridines as blue-emitting luminophores. It can also be used to prepare indoles (Indole, I577320) by a Pd-Catalyzed Cascade process. Group: Biochemicals. Grades: Highly Purified. CAS No. 2732-80-1. Pack Sizes: 1g, 5g. Molecular Formula: C7H6BrClO. US Biological Life Sciences. | Worldwide |
| (3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt | (3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (βR,δS)-6-Cyclopropyl-10-fluoro-7,8-dihydro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid Sodium Salt. Molecular formula: C25H23FNNaO4. Mole weight: 443.44. | |
| 6-Phenylphenathridine-3,8-diamine | 6-Phenylphenathridine-3,8-diamine. Group: Biochemicals. Alternative Names: 3,8-Diamino-6-phenylphenanthridine6-phenyl-3,8-phenanthridinediamine. Grades: Highly Purified. CAS No. 52009-64-0. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C19H15N3. US Biological Life Sciences. | Worldwide |
| bis[6-(5,6-dihydrochelerythrinyl)]amine | Bis[6-(5,6-dihydrochelerythrinyl)]amine is found in Zanthoxylum nitidum, which shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus. Synonyms: 13,13'-Iminobis(1,2-dimethoxy-12-methyl-12,13-dihydro[1,3]benzodioxolo[5,6-c]phenanthridine); Bis(1,2-dimethoxy-12-methyl-12,13-dihydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-13-yl)amine. Grades: > 95%. CAS No. 165393-48-6. Molecular formula: C42H37N3O8. Mole weight: 711.76. | |
| Dihydrexidine | Dihydrexidine. Group: Biochemicals. Alternative Names: (6aR,12bS)-rel-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol; trans-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol. Grades: Highly Purified. CAS No. 123039-93-0. Pack Sizes: 1mg. Molecular Formula: C17H17NO2, Molecular Weight: 267.32. US Biological Life Sciences. | Worldwide |
| Dihydrexidine hydrochloride | Dihydrexidine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Dihydrexidine hydrochloride;(+/-)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride. Product Category: Heterocyclic Organic Compound. CAS No. 123039-93-0. Molecular formula: C17H17NO2.HCl. Mole weight: 303.78. Purity: >99 %. Product ID: ACM123039930. Alfa Chemistry ISO 9001:2015 Certified. | |
| Dihydrexidine hydrochloride | The hydrochloride salt form of Dihydrexidine, which has been found to be an effective full efficacy dopamine D1 agonist and show antiparkinsonism effects in vivo. Synonyms: (±)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride. Grades: ≥98% by HPLC. CAS No. 158704-02-0. Molecular formula: C17H17NO2.HCl. Mole weight: 303.79. | |
| Dihydrochelerythrine | Dihydrochelerythrine is a natural compound isolated from Corydalis yanhusuo; has antifungal activity.IC50 value:Target:in vitro: Dihydrochelerythrine showed the highest antifungal activity against B. cinerea Pers, with 98.32% mycelial growth inhibition at 50 μg/mL. Dihydrochelerythrine inhibited spore germination in vitro in a concentration-dependent manner. Dihydrochelerythrine appeared to be less cytotoxic since the viability of cells exposed to 20 microM dihydrochelerythrine for 24h was reduced only to 53%. A dose-dependent induction of apoptosis and necrosis by chelerythrine and dihydrochelerythrine was confirmed by annexin V/propidium iodide dual staining flow cytometry. Dihydrochelerythrine (4) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 12,13-Dihydro-1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridine. Product Category: Inhibitors. Appearance: Solid. CAS No. 6880-91-7. Molecular formula: C21H19NO4. Mole weight: 349.4. Purity: 95%+. Canonical SMILES: CN1C(C2=CC(OCO3)=C3C=C2C=C4)=C4C5=CC=C(OC)C(OC)=C5C1. Product ID: ACM6880917. Alfa Chemistry ISO 9001:2015 Certified. | |
| Dihydroethidium | Dihydroethidium is a cell-permeable blue fluorescent dye, which intercalates with nucleic acids and emits a red fluorescence detectable qualitatively by fluorescent microscopy or quantitatively by HPLC. It is a superoxide indicator. It exhibits blue fluorescence in the cytosol until oxidizedto ethidium, where it intercalates within the cell's DNA, staining its nucleus a bright fluorescent red. It is neuroprotective by reducing superoxide in mice after stroke. It has been used to detect reactive oxygen species during the phagocytic respiratory burst and for the detection of intracellular superoxide in cultured cells. Synonyms: Hydroethidine; PD-MY 003; 5-ethyl-5,6-dihydro-6-phenyl-3,8-phenanthridinediamine; 5-Ethyl-6-phenyl-6H-phenanthridine-3,8-diamine. Grades: ≥98%. CAS No. 104821-25-2. Molecular formula: C21H21N3. Mole weight: 315.4. | |
| Dihydroethidium | Dihydroethidium. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,7-Diamino-10-ethyl-9-phenyl-9,10-dihydrophenthridine,3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenthridine. Product Category: Other Fluorophores. Appearance: Pink solid. CAS No. 104821-25-2. Molecular formula: C21H21N3. Mole weight: 315.41. Purity: 95%+. IUPACName: 5-ethyl-6-phenyl-6H-phenanthridine-3,8-diamine. Canonical SMILES: CCN1C(C2=C(C=CC(=C2)N)C3=C1C=C(C=C3)N)C4=CC=CC=C4. Product ID: ACM104821252-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Dihydro sanguinarine | Dihydro sanguinarine. Group: Biochemicals. Alternative Names: 13,14-Dihydro-13-methyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine; 13,14-Dihydrosanguinarine; Hydrosanguinarine. Grades: Highly Purified. CAS No. 3606-45-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H15NO4. US Biological Life Sciences. | Worldwide |
| Dynemicin A | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. Dynemicin A has a strong killing effect on a variety of tumor cells at Pg/mL level. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1S,4R,4aR,14S,14aS)-1,4,4a,7,12,13,14,14a-Octahydro-6,8,11-trihydroxy-3-methoxy-1-methyl-7,12-dioxo-4a,14a-epoxy-4,14-(3-hexene-1,5-diyne-1,6-diyl)naphtho[2,3-c]phenanthridine-2-carboxylicacid; Dynemicin; BU 3420T. Grades: 95%. CAS No. 124412-57-3. Molecular formula: C30H19NO9. Mole weight: 537.47. | |
| Dynemicin M | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a-pentahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione. Grades: ≥98%. CAS No. 127003-54-7. Molecular formula: C29H23NO9. Mole weight: 529.49. | |
| Dynemicin O | It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a,17-hexahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione; (8R-(8alpha,9beta,14beta,17S*,18R*))-8,9,14,15-Tetrahydro-1,4,6,8,10,17-hexahydroxy-20-methoxy-18-methyl-9,8,14-(1)butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione. CAS No. 138370-12-4. Molecular formula: C29H23NO10. Mole weight: 545.49. | |
| Dynemicin P | It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-3β,4a,6,8,11,14a-hexahydroxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione; 9,8,14-(1)Butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione,8,9,14,15-tetrahydro-1,4,6,8,17,20-hexahydroxy-18-methyl-, (8R-(8alpha,9beta,14beta,17S*,18R*))-. CAS No. 138370-13-5. Molecular formula: C28H21NO9. Mole weight: 515.47. | |
| HLY78 | HLY78 is an activator of the Wnt/β-catenin pathway. It targets the DIX domain of Axin and potentiates the Axin-LRP6 association, thus promoting LRP6 phosphorylation and Wnt signaling transduction. In zebrafish embryos, HLY78 was shown to increase the expression of the conserved hematopoietic stem cell (HSC) markers, runx1 and cmyb. Synonyms: 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine. Grades: ≥98%. CAS No. 854847-61-3. Molecular formula: C17H17NO2. Mole weight: 267.3. | |
| Jadomycin B | Jadomycin B is an angucyclic natural product produced by Streptomyces venezuelae ISP5230. It exhibits antimicrobial, antitumor activity and inhibits aurora-B kinase and DNA cleaving. It was also shown to be effective against a variety of staphylococci. Synonyms: 1-(sec-butyl)-12-((4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-7-hydroxy-5-methyl-8H-benzo[b]oxazolo[3,2-f]phenanthridine-2,8,13(1H,3aH)-trione; 8H-Benzo(b)oxazolo(3,2-f)phenanthridine-2,8,13(1H,3aH)-trione, 12-((2,6-dideoxyhexopyranosyl)oxy)-7-hydroxy-5-methyl-1-(1-methylpropyl)-. Grades: ≥98% by HPLC. CAS No. 149633-99-8. Molecular formula: C30H31NO9. Mole weight: 549.6. | |
| Lycorine Hydrochloride | Lycorine Hydrochloride. Group: Biochemicals. Alternative Names: Licorin Hydrochloride; 3,3a-Didehydrolycoran-1α,2 β-diol Hydrochloride; (1α,2 β)-3,12-Didehydro-9,10-[methylenebis(oxy)]-galanthan-1,2-diol; 2,4,5,7,12b,12c-Hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol Hydrochloride; (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-Hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol. Grades: Highly Purified. CAS No. 2188-68-3. Pack Sizes: 50mg. Molecular Formula: C16H18ClNO4, Molecular Weight: 323.77. US Biological Life Sciences. | Worldwide |
| NK314 | NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes. The DNA breaks occurred within 1h after treatment with NK314 even without digestion of topoisomerase II by proteinase K, whereas etoposide required digestion of the enzyme protein in cleavable complex to detect DNA breaks. Pretreatment with topoisomerase II catalytic inhibitors, ICRF-193 and suramin, reduced both cleavable complex-mediated DNA breaks and proteinase K-independent DNA breaks, but protease inhibitors and nuclease inhibitors only decreased the latter. These results indicate that NK314 might affect topoisomerase II in the different manner from cleavable complex formation and activate intracellular proteinase and nuclease to produce DNA fragmentation. As a result of this unique mechanism of DNA breakage, NK314 showed substantial growth inhibition of topoisomerase II inhibitor-resistant tumors. Synonyms: NK-314; NK 314. Grades: 98%. CAS No. 208237-49-4. Molecular formula: C22H18ClNO4. Mole weight: 395.84. | |
| Pitavastatin Impurity 2 | (3R,5S)-5-(6-Cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (βR,δS)-6-Cyclopropyl-10-fluoro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid; Pitavastatin Impurity 2 (PP-2). Grades: 94%. CAS No. 1187966-93-3. Molecular formula: C25H22FNO4. Mole weight: 419.44. | |
| Pitavastatin Impurity 29 | Pitavastatin Impurity 29. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-cyclopropyl-10-fluorobenzo[k]phenanthridine. Molecular Formula: C20H14FN. Mole Weight: 287.33. Catalog: APB01338. |  |
| Pitavastatin Impurity 30 | Pitavastatin Impurity 30. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine. Molecular Formula: C20H16FN. Mole Weight: 289.35. Catalog: APB01334. | |
| Propidium Iodide ≥95% (HPLC) | Propidium Iodide is a phenanthridine compound, a class of compounds with reported activity against several species of trypanosomes. Propidium iodide may be used in flow cytometry to evaluate cell viability when used with other dyes that stain viable cells or cells that are early in the apoptosis process. Propidium iodide (PI) is a fluorescent dye [FW 668.41] that binds specifically to DNA. This property has led to its common use in evaluation of cell cycle, aneuploidy and apoptosis by flow cytometry. When excited by a laser light at 488nm, PI emits a signal that can be monitored by the red wavelength detector typically reserved for phycoerythrin (usually FL2). Propidium iodide is excluded from viable cells, thus analysis of DNA content in cells requires membrane permeabilization. In evaluation of apoptosis, PI is used to distinguish necrotic cells or cells in late stages of apoptosis, which have permeabilized membranes and thus bind PI, from viable cells or cells in early apoptosis whe Group: Biochemicals. Alternative Names: 3, 8-Diamino-5-[3- (diethylmethylammonio) propyl]-6-phenylphenanthridinium Iodide; 3,8-Diamino-5-(3-diethylaminopropyl)-6-phenylphenanthridinium Iodide Methiodide; [3- (3, 8-Diamino-6-phenyl-5-phenanthridinio) propyl]. Grades: Reagent Grade. CAS No. 25535-16-4. Pack Sizes: 25mg, 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| 2-(2-(4-Phenanthridin-6-yl)piperazin-1-yl)ethoxy)ethanol | A useful synthetic intermediate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C21H25N3O2, Molecular Weight: 351.44. US Biological Life Sciences. | Worldwide |
| 2-(2-(4-Phenanthridin-6-yl)piperazin-1-yl)ethoxy)ethanol-D8 | 2-(2-(4-Phenanthridin-6-yl)piperazin-1-yl)ethoxy)ethanol-D8 is a labelled analogue of 2-(2-(4-Phenanthridin-6-yl)piperazin-1-yl)ethoxy)ethanol (P312650). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C21H17D8N3O2, Molecular Weight: 359.49. US Biological Life Sciences. | Worldwide |
| 2, 3, 7, 8-Tetrahydroxy-5-methyl-benzo [c]phenanthridinium Chloride | 2, 3, 7, 8-Tetrahydroxy-5-methyl-benzo [c]phenanthridinium Chloride is an intermediate in the synthesis of Sanguinarium-13CD3 Chloride (S112502). Sanguinarium-13CD3 Chloride is the labeled analogue of Sanguinarium Chloride (S112500). Sanguinarium Chloride is a natural product with antimicrobial, anti-inflammatory, and anti-oxidant properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 1099740-10-9. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C18H14NO4+ + Cl-, Molecular Weight: 308.313544999999. US Biological Life Sciences. | Worldwide |
| 2-Bromobenzamide | 2-Bromobenzamide has been used in microwave assisted one-pot synthesis of substituted 3- (phenylmethylene) isoindolin-1-ones, palladium-catalyzed synthesis of phenanthridinones and synthesis of new water-soluble iminophosphorane ligand. Group: Biochemicals. Grades: Highly Purified. CAS No. 4001-73-4. Pack Sizes: 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| 2-Bromophenanthridone | 2-Bromophenanthridone is a 2-bromo substituted derivative of phenathridinone that exhibits aryl hydrocarbon (Ah) receptor antagonist activity. It is also used in the preparation of potential HIV-1 integrase inhibitors. Group: Biochemicals. Alternative Names: 2-Bromo-6(5H)-phenanthridinone; NSC 112910; SG 00589. Grades: Highly Purified. CAS No. 27353-48-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 3, 8-Bis (ethoxycarbonylamino)-5- (3-bromopropyl)-6-phenyl-phenanthridinium bromide | 3, 8-Bis (ethoxycarbonylamino)-5- (3-bromopropyl)-6-phenyl-phenanthridinium bromide. Group: Biochemicals. Alternative Names: 5- (3-Bromopropyl)-3, 8-bis[ (ethoxycarbonyl)amino]-6-phenyl-phenanthridinium bromide. Grades: Highly Purified. CAS No. 62113-49-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C28H29Br2N3O4. US Biological Life Sciences. | Worldwide |
| 3,8-Bis-ethoxycarbonylamino-5-(3-bromo-propyl)-6-phenyl-phenanthridinium bromide | 3,8-Bis-ethoxycarbonylamino-5-(3-bromo-propyl)-6-phenyl-phenanthridinium bromide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(3-Bromopropyl)-3,8-bis[(ethoxycarbonyl)amino]-6-phenyl-phenanthridinium Bromide. Product Category: Heterocyclic Organic Compound. Appearance: Yellow Solid. CAS No. 62113-49-9. Molecular formula: C28H29Br2N3O4. Mole weight: 631.3556. Purity: 0.96. IUPACName: ethyl N-[5-(3-bromopropyl)-3-(ethoxycarbonylamino)-6-phenylphenanthridin-5-ium-8-yl]carbamate;bromide. Canonical SMILES: CCOC(=O)NC1=CC2=C([N+](=C3C=C(C=CC3=C2C=C1)NC(=O)OCC)CCCBr)C4=CC=CC=C4.[Br-]. Density: g/cm³. ECNumber: 263-412-1. Product ID: ACM62113499. Alfa Chemistry ISO 9001:2015 Certified. | |
| 3,8-Bis-ethoxycarbonylamino-5-(3-bromo-propyl)-6-phenyl. -phenanthridinium Bromide. | 3,8-Bis-ethoxycarbonylamino-5-(3-bromo-propyl)-6-phenyl-phenanthridinium Bromide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 3,8-Bis-ethoxycarbonylamino-5-(3-diethylamino-propyl)-6-phenyl-. phenanthridinium Chloride. | 3,8-Bis-ethoxycarbonylamino-5-(3-diethylamino-propyl)-6-phenyl-phenanthridinium Chloride. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 6(5H)-phenanthridinone | 6(5H)-phenanthridinone. CAS No: 1015-89-0 |  Sarchem Laboratories New Jersey NJ |
| 6(5H)-Phenanthridinone | 6(5H)-Phenanthridinone is a potent PARP-1 inhibitor and immunomodulator. 6(5H)-Phenanthridinone inhibits cell proliferation and can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1015-89-0. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-34386. |  |
| 6-Phenanthridone | 6-Phenanthridone is a poly(ADP-ribose) polymerase (PARP) inhibitor with immunosuppressive effects. 6-Phenanthridone has been shown to inhibit concanavalin A-induced lymphocyte proliferation. Group: Biochemicals. Alternative Names: 5H-Phenanthridin-6-one; 6-Phenanthridinol; 6-Phenanthridinone; 6-Phenanthridone; NSC 11021; NSC 40943; NSC 61083; PJ 97A; 6(5H)-Phenanthridinone; WD 99-004344. Grades: Highly Purified. CAS No. 1015-89-0. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| a-Allocryptopine | a-Allocryptopine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: HOMOCHELIDONINE;HOMOCHELIDONINE, A-;A-ALLOCRYPTOPINE;A-HOMOCHELIDONINE;ALPHA-HOMOCHELIDONINE;[4bR-(4balpha,5beta,11balpha)]-4b,5,6,11b,12,13-hexahydro-1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-5-ol;HOMOCHELIDONINE, a-(P);(4bR)-4b,5,6,1. Product Category: Heterocyclic Organic Compound. CAS No. 476-33-5. Molecular formula: C21H23NO5. Mole weight: 369.41. Purity: 0.96. IUPACName: (4bR,5S,11bS)-1,2-dimethoxy-12-methyl-5,6,11b,13-tetrahydro-4bH-[1,3]benzodioxolo[5,6-c]phenanthridin-5-ol. Canonical SMILES: CN1CC2=C(C=CC(=C2OC)OC)C3C1C4=CC5=C(C=C4CC3O)OCO5. Density: 1.294g/cm³. ECNumber: 207-505-7. Product ID: ACM476335. Alfa Chemistry ISO 9001:2015 Certified. | |
| Acetylcorynoline | Acetylcorynoline, which can be extracted from the tubers of Corydalis ambigua, inhibits the maturing of bone marrow-derived dendritic cells in mice. However, it is only cytotoxic in amounts of greater than 20 μM. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. Acetylcorynoline significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; prevents α-synuclein aggregation; recovers lipid content in OW13 strain; restores food-sensing behavior, and dopamine levels; and prolongs life-span in 6-hydroxydopamine-treated N2 strain, thus showing its potential as a possible antiparkinsonian drug. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes. Uses: Antifungal/anti-inflammatory. Synonyms: (5bR,6S,12bR)-5b,6,7,12b,13,14-Hexahydro-5b,13-dimethyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol 6-acetate; Corynoline acetate; O-Acetylcorynoline; [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, 6-acetate, (5bR,6S,12bR)-. Grades: >98%. CAS No. 18797-80-3. Molecular formula: C23H23NO6. Mole weight: 409.43. | |
| Candesartan Impurity 31 | Candesartan Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(((cyclohexyloxy)carbonyl)oxy)ethyl 2-ethoxy-1-(tetrazolo[1,5-f]phenanthridin-6-ylmethyl)-1H-benzo[d]imidazole-7-carboxylate. CAS No. 1821385-89-0. Molecular Formula: C33H32N6O6. Mole Weight: 608.64. Catalog: APB1821385890. | |
| Candesartan Impurity 32 | Candesartan Impurity 32. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-ethoxy-1-(tetrazolo[1,5-f]phenanthridin-6-ylmethyl)-1H-benzo[d]imidazole-7-carboxylic acid. CAS No. 1821386-35-9. Molecular Formula: C24H18N6O3. Mole Weight: 438.44. Catalog: APB1821386359. | |
| Chelerythrine | Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 μM. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 μM and displaces Bax from BclXL. Chelerythrine triggers apoptosis and autophagy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Broussonpapyrine; Cheleritrine; Chelerythrin; Chelerythrine chloride; Chelerythrin-Kation; Chelerythrine; Chelerythrin chlorid. Product Category: Inhibitors. CAS No. 34316-15-9. Molecular formula: C21H18ClNO4. Mole weight: 348.83. Purity: 95%-99%. IUPACName: 1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium. Canonical SMILES: C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5. ECNumber: 251-930-0. Product ID: ACM34316159. Alfa Chemistry ISO 9001:2015 Certified. | |
| Chelerythrine chloride | Cell permeable potent inhibitor of protein kinase C. Does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase or calcium/calmodulin-dependent protein kinase. Antiplatelet, anti-inflammatory, antibacterial and antitumor compound. Apoptosis inducer in cancer cells in vitro and in vivo. Activates MAPK and JUNK signaling pathways. Affects translocation of PKC from cytosol to plasma membrane. Neurite outgrowth stimulator. Inhibits binding of BclXL to Bak (IC50 =1.5uM) or Bad proteins and stimulates apoptosis in several cancer cell lines. Blocks human P2X7 receptor. Induces cell cycle arrest in G1 phase. Specific cyclooxygenase-2 inhibitor. Group: Biochemicals. Alternative Names: NSC 36405, 1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride. Grades: Highly Purified. CAS No. 3895-92-9. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C21H18ClNO4. US Biological Life Sciences. | Worldwide |
| Chelerythrine chloride | Chelerythrine chloride is a potent, cell-permeable inhibitor of protein kinase C, with an IC50 of 660 nM. Chelerythrine chloride inhibits the Bcl-XL-Bak BH3 peptide binding with IC50 of 1.5 μM and displaces Bax from Bcl-XL. Chelerythrine chloride induces apoptosis and autophagy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,2-Dimethoxy-12-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-12-ium chloride. Product Category: Inhibitors. CAS No. 3895-92-9. Mole weight: 383.8. Purity: 95%+. Product ID: ACM3895929. Alfa Chemistry ISO 9001:2015 Certified. | |
| CY 208-243 | CY 208-243 is a D1DR receptor agonist and has been found to show antiparkinsonian activity in animal models. Synonyms: CY 208-243; CY-208-243; CY208243; (-)-(6aR,12bR)-4,6,6a,7,8,12b-Hexahydro-7-methylindolo[4,3-a]phenanthridin. Grades: ≥95% by HPLC. CAS No. 100999-26-6. Molecular formula: C19H18N2. Mole weight: 274.36. | |
| Dimidium Bromide | Dimidium bromide is an inhibitor of L-cell growth. Dimidium Bromide is used as an intercalating probe for nucleic acids. Group: Biochemicals. Alternative Names: 3,8-Diamino-5-methyl-6-phenylphenanthridinium Bromide; Dimidium bromide; Phenanthridinium Compound 1553; Phenanthridium 1553; Trypadine. Grades: Highly Purified. CAS No. 518-67-2. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| Ethidium bromide-N N-bisacrylamide | Ethidium bromide-N N-bisacrylamide. Group: other materials. Alternative Names: ETHIDIUM BROMIDE-N N-BISACRYLAMIDE; 3,8-bisacrylamido-5-ethyl-6-phenylphenanthridinium bromide; 3,8-Bisacrylamido-5-ethyl-6-phenylphenanthridiniumbromide,3,8-Bisacryloylethidiumbromide. CAS No. 480438-67-3. Product ID: N-[5-ethyl-6-phenyl-3-(prop-2-enoylamino)phenanthridin-5-ium-8-yl]prop-2-enamide; bromide. Molecular formula: 502.4g/mol. Mole weight: C27H24BrN3O2. CC[N+]1=C2C=C (C=CC2=C3C=CC (=CC3=C1C4=CC=CC=C4)NC (=O)C=C)NC (=O)C=C. [Br-]. InChI=1S/C27H23N3O2. BrH/c1-4-25 (31)28-19-12-14-21-22-15-13-20 (29-26 (32)5-2)17-24 (22)30 (6-3)27 (23 (21)16-19)18-10-8-7-9-11-18; /h4-5, 7-17H, 1-2, 6H2, 3H3, (H, 28, 31); 1H. VVSGFSHAUFPBFM-UHFFFAOYSA-N. | |
| Glutaminase C-IN-1 | Glutaminase C-IN-1, with effect to suppresse breast cancer cell growth and invasive activity in vitro, it is an allosteric, cell-permeable and reversible inhibitor of lutaminase C (IC50 = ~2.5 μM). Synonyms: GLS-IN-968; GLS IN 968; GLSIN968; Glutaminase inhibitor-968; Glutaminase inhibitor 968; GLS inhibitor 968; Glutaminase inhibitor compound 968; 5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-1,3,5,6-tetrahydrobenzo[a]phenanthridin-4-one5-(3-bromo-4-(dimethylamino)phenyl)-2,2-dimethyl-2,3,5,6-tetrahydrobenzo(a)phenanthridin-4(1H)-one. CAS No. 311795-38-7. Molecular formula: C27H27BrN2O. Mole weight: 475.42. | |
| Glutaminase Inhibitor, Compound 968 (5- (3-Bromo-4- (dimethylamino) phenyl) -2, 2-dimethyl-2, 3, 5, 6-tetrahydrobenzo [a]phenanthridin-4 (1H) -one, GAC Inhibitor, GLS1 Inhibitor I, KGA Inhibitor I, Kidney-Type Glutaminase Inhibitor I) | A cell-permeable benzophenanthridinone compound that acts as an allosteric and reversible inhibitor of mitochondrial glutaminase activity and represses the growth and invasive activity in glutaminase upregulated fibroblasts and in tumor cells (IC50 <10uM in NIH3T3 cells stably expressing Dbl, Cdc42-F28L, Rac-F28L or RhoC-F30L mutants and in SKBR3 and MDA-MB231 cancer cells). Shown to effectively shrink tumor size in P-493 B xenografted mouse model (200 µg per inj. i.p., 12 days). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Macleaya cordata extract | Macleaya cordata extract. Uses: Designed for use in research and industrial production. Additional or Alternative Names: chelerythrine chloride-sanguinarine chloride mixt.;Macleaya cordata extract;13-Methyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium chloride mixt. with 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride;13-Methyl-[1,3]. Product Category: Heterocyclic Organic Compound. CAS No. 112025-60-2. Molecular formula: C20H14NO4.Cl;C21H18NO4.Cl. Mole weight: N/A. Product ID: ACM112025602. Alfa Chemistry ISO 9001:2015 Certified. | |
| Narciclasine | Narciclasine, which can be found in the tubers of Narcissus tazetta, displays marked proapoptotic and cytotoxic activity, as does pancratistatin, and significant in vivo anticancer effects in various experimental models. It is a potential agent for the treatment of primary brain cancers and various brain metastases. Uses: Anti-inflammatory. Synonyms: (13β)-1,19-Didehydro-2α,3β,4β,7-tetrahydroxy-11,12-dinor-5,19-secocrinan-6-one; (2S)-3,4,4aβ,5-Tetrahydro-2α,3β,4β,7-tetrahydroxy[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one; Lycorcidinol. Grades: ≥95%. CAS No. 29477-83-6. Molecular formula: C14H13NO7. Mole weight: 307.25. | |
| Oxylycorine | Oxylycorine is a selective topoisomerase II beta poison. It inhibits the growth of human tumour cells. It also inhibits the growth of human leukaemia cell lines. Uses: Oxylycorine inhibits the growth of human tumour cells. it also inhibits the growth of human leukaemia cell lines. Synonyms: AT-1840; AT 1840; AT1840; Ungerimine acetate; Lycobetaine acetate; 2-Hydroxy-4,5-dihydro-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridin-6-ium acetate. Grades: 98%. CAS No. 61221-41-8. Molecular formula: C18H15NO5. Mole weight: 325.32. | |
| Pitavastatin Impurity 16 | Pitavastatin Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1187966-93-3(free base); sodium (3R,5S)-5-(6-cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoate. Molecular Formula: C25H21FNO4·Na. Mole Weight: 441.43. Catalog: APB01344. | |
| Pitavastatin Impurity 36 | Pitavastatin Impurity 36. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1187966-91-1 (free acid); sodium (3R,5S)-5-(6-cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoate. Molecular Formula: C25H23FNNaO4. Mole Weight: 443.44. Catalog: APB01330. | |
| Pitavastatin Impurity 39 | Pitavastatin Impurity 39. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4R,6S)-6-((R)-6-cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. Molecular Formula: C32H36FNO4. Mole Weight: 517.63. Catalog: APB01329. | |
| Pitavastatin Impurity 40 | Pitavastatin Impurity 40. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4R,6S)-6-((S)-6-cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. Molecular Formula: C32H36FNO4. Mole Weight: 517.63. Catalog: APB01328. | |
| Pitavastatin Impurity 42 | Pitavastatin Impurity 42. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4R,6S)-6-(6-cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. Molecular Formula: C32H34FNO4. Mole Weight: 515.62. Catalog: APB01327. | |
| Pitavastatin Impurity 49 | Pitavastatin Impurity 49. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,5S)-tert-butyl 5-((R)-6-cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoate. Molecular Formula: C29H32FNO4. Mole Weight: 477.57. Catalog: APB01432. | |
| Pitavastatin Impurity 50 | Pitavastatin Impurity 50. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,5S)-tert-butyl 5-((S)-6-cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoate. Molecular Formula: C29H32FNO4. Mole Weight: 477.57. Catalog: APB01431. | |
| Pitavastatin Impurity 52 | Pitavastatin Impurity 52. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1422058-52-3(free base); calcium (3R,5S)-5-((S)-6-cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoate. Molecular Formula: 2C25H23FNO4·Ca. Mole Weight: 880.98. Catalog: APB01430. | |
| Pitavastatin Impurity 53 | Pitavastatin Impurity 53. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1422058-51-2(free base); monocalcium mono((3R,5S)-5-((R)-6-cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoate). Molecular Formula: 2C25H23FNO4-·Ca. Mole Weight: 880.98. Catalog: APB01428. | |
| PJ 34 Hydrochloride | A poly adenosine diphosphate-ribose polymerase inhibitor, attenuates chromate-induced nephrotoxicity. Group: Biochemicals. Alternative Names: N- (5, 6-Dihydro-6-oxo-2-phenanthridinyl) -2- (dimethylamino) acetamide. Grades: Highly Purified. CAS No. 344458-15-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
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